2023 University of Michigan Kellogg Eye Center Annual Report

Page 26

David Antonetti, Ph.D., Shahzad Mian, M.D., David Zacks, M.D., Ph.D., Patrice Fort, Ph.D., M.S.

Institutional Grants Anchor Research Infrastructure, Training

The P30 center grant funds state-of-the-science instrumentation, services and training for vision researchers to connect and pursue cutting edge ideas. The center has research cores, each supervised by faculty and staffed by technical experts:

Functional Assessment—This core, directed by P30 Kellogg researchers are among the most productive, Principal Investigator David Antonetti, Ph.D., provides grant-supported, published and cited in all of ophthaltraining and support to investigators performing nonmology. How do we attract and retain the best and the lethal measures of ocular structure and function, includbrightest? With a structure and culture that fosters ining optical coherence tomography, electroretinography, novation and collaboration. fundus imaging, and pupillometry. “Our research program is designed to be both a magnet for the most creative minds, and an incubator Instrument and Electronics— for their most original ideas,” says Directed by James Weiland, Ph.D., OUR RESEARCH PROGRAM IS Kellogg Interim Chair Shahzad Mian, this core provides and maintains M.D. “We’re continuously improvDESIGNED TO BE BOTH A MAGNET specialized instrumentation — ing the fundamentals— our mix of FOR THE MOST CREATIVE MINDS, both commercially available and technologies and resources, training custom built—for use by NEIAND AN INCUBATOR FOR THEIR and support—to meet the changing funded investigators. MOST ORIGINAL IDEAS. needs of researchers from dozens Molecular Biology— directed by of specialties, pursuing hundreds of — Shahzad Mian, M.D. Steven Abcouwer, Ph.D., this core lines of investigation.” offers services, equipment and support for projects Kellogg’s research enterprise is anchored by four involving molecular biology, statistical genetics, and interconnected institutional grants, supporting basic, bioinformatics. clinical and translational investigators at every career stage. All four grants were renewed this fiscal year, and a new core facility was added.

National Institutes of Health (NIH) / National Eye Institute (NEI) University of Michigan Vision Research Center (UMVRC) Grant (P30) The University of Michigan holds one of the longest standing P30 Center Grants in ophthalmology and visual sciences. Center grants provide resources and facilities for core services shared by researchers across the University that carry out vision research. 24

Morphology and Imaging— this core, directed by Jillian Pearring, Ph.D., processes ocular and brain tissue samples for light microscopy, immunocytochemistry and in situ hybridization, and fixes specimens for electron microscopy. Assistance in analysis and presentation of imaging results is also available, and the core is a hub for training investigators in tissue processing, microtomy, staining and immunohistology techniques.


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Articles inside

Partnership between U-M Med School, Business School, and the Kellogg Eye Center Drives Latest Kenya

4min
pages 38-39

The Edna H. Perkiss Research Professorship in Ophthalmology and Visual Sciences

3min
page 37

Honoring the Visionary Leadership of Paul P. Lee, M.D., J.D.

3min
page 36

The Alan Sugar, M.D., Research Professorship in Ophthalmology

3min
page 35

Mark W. Johnson, M.D., Honored with Heed-Gutman Award

2min
page 34

Protecting Retinal Neurons from Diabetes

2min
page 34

Mining Big Data for Novel Glaucoma Genes

3min
page 33

Beyond the Electronic Health Record

5min
pages 32-33

Applauding a Good Catch

2min
page 31

Microneedles for Sustained Retinal Drug Delivery

2min
page 30

Alumni Highlights

4min
pages 29-30

Lecture in Professionalism and Ethics

1min
page 29

Molecular Imaging of Macular Degeneration

2min
page 28

Institutional Grants Anchor Research Infrastructure, Training

5min
pages 26-27

2023-2024 Heed Fellows

5min
pages 24-25

Pre-Med Awarded NIH Research Supplement

2min
page 23

Kellogg PGY4 Sole Resident on ACGME Residency Program Review Committee

2min
page 22

Kellogg Post-Doc Receives Prestigious NIH Grant

2min
page 21

An Out-of-This-World Perspective on Residency from one of Forbes’ Thirty-Under-Thirty

3min
page 20

Expanding Personalized Treatment and Clinical Research in Uveitis

3min
page 19

KCRC Assists in Michigan Medicine Research with Consequences for Eyes

3min
page 18

Editing Genes to Treat Corneal Dystrophies

3min
page 17

Using Artificial Intelligence to Improve IOL Formulas

3min
page 16

Selfless Service Beyond Kellogg’s Walls

1min
page 15

The Genes That Drive Eye Size

2min
page 15

Image-Guided Medical Robotics Comes to Kellogg

3min
page 14

How Inflammation Triggers Photoreceptor Regeneration

2min
page 13

The Molecular Physiology of the Blood-Retinal Barrier

3min
page 12

Prioritizing Patient Wellness—and Our Own

3min
page 11

Michigan's 15th President Joins the Department

3min
page 10

Patent Issued for Photo-Mediated Ultrasound Therapy

1min
page 9

Unlocking the Therapeutic Potential of Tears

2min
page 9

Oculoplastics: Building on an Extraordinary Legacy

3min
page 8

Assessing Age-Related Vision Impairment

3min
page 7

For IRD Patients, Tailored Interventions Address Impaired Vision and Related Distress

3min
page 6

A Rare Syndrome, A Team Approach

4min
pages 4-5

2023 University of Michigan Kellogg Eye Center Annual Report

3min
page 3
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