August 2013 Refill

08 AUGUST 2013

E-NEWSLETTER OF THE NATIONALLY RANKED UNIVERSITY OF TOLEDO COLLEGE OF PHARMACY AND PHARMACEUTICAL SCIENCES

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Dr. Wayne Hoss Retires

In Memoriam: Dr. Miles Hacker P.2

Dr. Wayne Hoss, executive associate dean of the College of Pharmacy and Pharmaceutical Sciences, will retire in June 2013 after 28 years of service to the university.

Dr. Hoss joined the faculty of The University of Toledo in 1985 as a professor of medicinal chemistry. He later added the responsibility of codirecting the Center for Drug Design and Development for a brief period before spending nearly a decade as the university‟s associate vice president for research and development. Dr. Hoss returned to the College of Pharmacy and Pharmaceutical Sciences in 1999 as the interim dean before taking on the role of associate dean and later executive associate dean, the position he now holds.

Best Postgrad Paper at APhA P.4

Meet Dr. Salah Ahmed P.3

Students of the Month P.5 Photo by Dan Miller

Upcoming Events P.5

New leadership appointments reflect growth in the College of Pharmacy and Pharmaceutical Sciences The College of Pharmacy and Pharmaceutical Sciences at The University of Toledo is pleased to announce new administrative appointments that affect the college‟s governance.

Executive Associate Dean

Dr. Hoss‟s leadership and vision have been a driving factor behind many of the

The college‟s newly appointed executive associate dean is Christine Hinko, PhD. Dr. Hinko has also been the associate dean for Student Affairs in the College of Pharmacy and Pharmaceutical Sciences for thirteen years and is a professor of pharmacology. She and the Student Affairs staff have been recognized repeatedly by the university for outstanding advising and for the expert management of student affairs on two campuses. The success of the Office of Student Affairs was recently commended by the Accreditation Council for Pharmacy Education. Dr. Hinko‟s new role will allow continuous college-level decision making while the dean addresses outreach and engagement and capital campaign assignments.

continued on page 2

Dr. Hinko assumes the role of executive

associate dean following the recent retirement of Dr. Wayne Hoss, who served as the college‟s executive associate dean for ten years.

Associate Dean for Research and Graduate Programs Marcia McInerney, PhD is the new associate dean for Research and Graduate Programs. Dr. McInerney, whose most recent role was that of chair of the Department of Medicinal Chemistry, is a Distinguished University Professor who has been part of The University of Toledo‟s faculty since 1991.

Her research on Type 1 and Type 2 diabetes has earned her multiple awards and national recognition in addition to millions of dollars in grant funding from private and federal agencies. Dr. McInerney will lead the highly attractive graduate programs in the pharmaceutical sciences, to which Learners from a multitude of domestic and international institutions seek admission in numbers that exceed our current capacity. The graduate programs in the College of Pharmacy and continued on page 6

Dr. Hoss

In Memoriam: Dr. Miles Hacker Dr. Miles P. Hacker passed away in July of 2013, having served on The University of Toledo College of Pharmacy and Pharmaceutical Sciences faculty for more than ten years as a professor of pharmacology and a master teacher. During his service on the faculty, Dr. Hacker was named Professor of the Year, an award indicative of the admiration students had for him. Dr. Hacker is one of the authors of Pharmacology: Principles and Practice, a textbook that represents the tremendous and universally recognized expertise of faculty members at The University of Toledo. An advisor for the college‟s Bachelor of Science in Pharmaceutical Sciences program, he was instrumental in establishing the program and developing its curriculum. Dr. Hacker also made substantial contributions toward the establishment of the doctoral degree in experimental therapeutics.

Among his research accomplishments, Dr. Hacker developed pixantrone, a cancer medication that inhibits DNA synthesis of cancer cells, contributing to the field of cancer research and treatment worldwide. His vast knowledge of pharmacology has benefitted and continues to enrich the students, alumni and faculty of The University of Toledo College of Pharmacy and Pharmaceutical Sciences.

continued from page 1 college‟s successes over the years. He is involved in every aspect of the college, from research and graduate studies to ensuring that the college‟s facilities are the best in the region and that the college exceeds the standards set by its accrediting body.

In addition to his roles in academia, Dr. Hoss remains closely involved in research.

He is a director at Mithridion, Inc., a biopharmaceutical company that focuses on treatments for neurological and psychiatric disorders, including Alzheimer's disease and schizophrenia.

Alumna Krystalyn Weaver accepts NASPA position

Weaver, far right, with (L-R) UT alumni Ken Hohmeier, PharmD „10; David Bright, PharmD „08; and Andrea Brookhart, PharmD „12 on the terrace at the American Pharmacists Association headquarters.

The National Alliance of State Pharmacy Associations (NASPA) recently announced the hiring of Krystalyn Weaver, for the newly created position of Director of Policy and State Relations.

She graduated in 2012 from The University of Toledo College of Pharmacy and Pharmaceutical Sciences with a Doctor of Pharmacy degree.

She is a member of the Ohio and Virginia Pharmacists Associations, APhA, ASAE, ASHP, and NCPA. Weaver served as the executive

resident of the APhA Foundation from July 2012 to present.

Rebecca Snead, NASPA EVP/ CEO.

While enrolled at The University of Toledo, she served as Student Body President and as a Student Trustee on the UT Board of Trustees. She also completed a community pharmacy internship with Giant Eagle Pharmacy.

“We are thrilled that Krystalyn accepted the opportunity to work with state pharmacy associations, NASPA associate members and our national partners on these important issues,” said Snead.

Regarding her new position, Weaver said, "I'm honored and excited to have the opportunity to work with NASPA to assist the state associations in their efforts to advance pharmacy and serve their members."

The National Alliance of State Pharmacy Associations (NASPA) promotes leadership, sharing, learning, and policy exchange among state pharmacy associations and pharmacy leaders nationwide, and provides education and advocacy to support pharmacists, patients, and communities working together to improve public health. NASPA was founded in 1927 as the National Council of State Pharmacy Association Executives (NCSPAE).

In her role with NASPA, Weaver will focus on state healthcare policy, tracking emerging healthcare trends affecting pharmacy and the patients they serve, and working with all partners to accelerate the spread of practice innovation and pharmacist provided patient care services. Weaver will report to

Research Publications for recent grad

Meet Dr. Salah Ahmed

Dr. Ahmed, far right, with students Maria Beamer, Sharaya Riegsecker, Wylie Wingerter, Karissa Kottier, and Yeahwa Hong. Sharayah Riegsecker, a graduate student, received the prestigious ACR/REF Abbott Health Graduate Research Preceptorship Award.

Dr. Salah Ahmed is an assistant professor in the Department of Pharmacology.

Dr. Ahmed‟s Arthritis Research lab is funded by the grants from NIH and pharmaceutical industry. His group has published research work in high-impact journals including Proceedings of the National Academy of Sciences, USA, Arthritis & Rheumatism, Journal of Pharmacology & Experimental Therapeutics, Molecular Interventions, and Frontiers in Immunology.

Dr. Ahmed has been invited to serve as a reviewer for the NIH and Arthritis Foundation grants. Currently, he also serves as a Lead Guest Editor on the Special Issue of the journal Mediators of Inflammation and as an expert reviewer for several journals.

Dr. Ahmed has received awards from the American Society for Pharmacology and Experimental Therapeutics (ASPET), the American College of Rheumatology (ACR), and the International Union of Pharmacology

(IUPHAR).

Rheumatoid arthritis (RA), a chronic inflammatory joint disorder, is a leading cause of work-related disabilities and a significant socio-economic health challenge due to expensive, yet incomplete, conventional therapies. Using synovial fibroblasts isolated from RA patients and animal models of human RA, we are testing the efficacy of epigallocatechin-3-gallate (EGCG), a potential antiinflammatory molecule found in green tea, in regulating the synthesis and detrimental effects of interleukin-6 (IL-6) in RA. The success of the proposed experiments may lead to a significant advancement in the development of EGCG as a potentially safe and inexpensive treatment option for RA. Dr. Ahmed has received a fiveyear R01 NIH funding to study the mechanisms through which EGCG inhibits inflammation and tissue destruction in RA. Patients suffering from RA

tend to develop cardiovascular complications. His research focus in this area is to study the role of pro-inflammatory cytokines and downstream inflammatory mediators in the manifestation of cardiovascular complications in RA. Based on these findings, his lab plans to test potential novel antiinflammatory molecules in clinical intervention studies.

The success of these studies may lead to a significant advancement in the development of EGCG or structurally related molecules as potential treatment options for RA and possibly other autoimmune diseases.

Dr. Ahmed‟s most rewarding contribution has been the training of undergraduates and graduates for research careers in pharmacology and experimental therapeutics. He has trained students who went on to publish research and review articles, present posters at the scientific meetings, and successfully enter PhD programs of various research universities.

Shao

Lo,

PharmD

’13, has worked with Dr. Surya Nauli in the research field of cilia biology and polycystic kidney disease (PKD).

PKD is a devastating genetic disease that is characterized

by

various cardiovascular abnormalities, including hypertension.

The

research

accomplishments

of

Dr. Lo are reflected by three

prominent

publications Sensors

in journal,

Faseb Journal and a book

chapter

in

Mechanosensitivity and Mechanotransduction (ISBN:

978-90-481-

9880-1). Dr. Lo intends pursue

a

academic with

career

in

pharmacy

involvement

hospital pharmacy.

in

Alumni at OSHP Annual Meeting

Best Postgraduate Paper at APhA

L-R: Cappelletty, Moorman, Frazee and Zaucha

At the 2013 Ohio Society of Health-System Pharmacists (OSHP) Annual Meeting, UT pharmacy alumni were honored for their work in academia and in the local and global communities.

Dr. Diane Cappelletty, associate professor of Pharmacy Practice, received the OSHP Humanitarian Award for her years of service through area free clinics and international medical mission trips to Central and South America and Africa. Dr. Cappelletty was featured in the June 2013 issue of Refill.

John Moorman, PharmD ‟09, was named Health System Pharmacist of the Year.

Larry Frazee, PharmD ‟93 and current UT CPPS preceptor, received the Health System Pharmacy Practice Researcher of the Year Award.

Julie Zaucha, BS Pharm ‟92, received the OSHP Timothy D. Moore Pharmacy Management Award.

Monita Karmakar, a graduate of the Health Outcomes and Socioeconomic Sciences graduate program, won the award for the Best Postgraduate Paper in the Economic Social and Administrative Science category at the American Pharmacists Association meeting. Monita completed her research with Dr. Sharrel Pinto, director of the Pharmaceutical Care and Outcomes Research lab in the Department of Pharmacy Practice. The paper, entitled “Predicting Adherence to Aromatase Inhibitor Therapy in Patients with Breast Cancer Using Protection Motivation

Theory,” was one of 69 accepted for presentation in this category and was a result of Monita‟s thesis research. Co-authors are Dr. Pinto, Dr. Monica Holiday-Goodman, Dr. Timothy Jordan from Health Education and Dr. Iman Mohamed from the College of Medicine.

This award is remarkable because of the hearty competition in the category from colleges of pharmacy across the country, nonacademic pharmacy-based institutions such as hospitals and long-term care facilities, and pharmacy chains. While a nomination in itself is rare, it

is uncommon for work done in a master‟s program to win such an award when competing with doctoral dissertations and institutions that have considerable resources. A paper from UT also earned this award in 2009. This recognition by APhA validates the high quality of research done in the College of Pharmacy and Pharmaceutical Sciences.

Monita Karmakar, pictured above (left) with Dr. Sharrel Pinto, is currently pursuing a PhD in The Health Education department at UT.

Dean’s Commission on Pharmacy Education The Dean‟s Commission on Pharmacy Education, an advisory group that focuses on the intersection of pharmacy education and the pharmacy industry, meets twice annually to discuss current issues with the college‟s leadership team. A highlight of the biannual meetings is the Starving Student Dinner, during which students network with Commission members.

Rewarding Excellence: 2013 Students of the Month The College of Pharmacy and Pharmaceutical Sciences Student of the Month Award was initiated in January 2013 and has allowed the college to recognize outstanding students. Full time students in the preprofessional division, professional division, or MS or PhD programs were eligible to be nominated by CPPS students, faculty, staff or preceptors.

Students with a cumulative grade point average of 3.0 or greater were eligible for the award, and the college‟s Professional Conduct Committee made the final decisions. This award recognizes students who served as a role models of professionalism to the student body; display a strong commitment to leadership in the College, University, community and/ or chosen profession; and dedicate their time and talents to help others through volunteering.

The Student of the Month for January 2013 was Sarah Breen, a BS in Pharmaceutical Sciences student who is majoring in Cosmetic Science.

Sarah is recognized for her strong work ethic, commitment to the success of the Cosmetic Science program and active participation in student organizations.

Her tremendous work with Lambda Kappa Sigma to organize the First

Aid activities for the Girl Scouts and her continual high achievement were among the cited reasons that earned her the Student of the Month award.

Michelle Carey earned the February 2013 Student of the Month award because of her exceptional work in coordinating the college's Script Your Future Challenge, a national campaign to improve medication adherence. The challenge took place during the month of February, and Michelle coordinated events and engaged students from the College of Pharmacy and Pharmaceutical Sciences as well as the College of Medicine and Life Sciences. By involving the college in this national challenge, Michelle encouraged interactions with patients and promoted patient counseling. Michelle was one of two valedictorians for the 2013 Doctor of Pharmacy graduating class.

Pranav Patel was the March 2013 Student of the Month award because of his engagement with managed care pharmacy. During a recent rotation in the UTMC pharmacy, he completed multiple medication therapy

management projects, helped to develop the cost saving Nexium program, and worked on the development of business plans for the transplant program. He has helped to increase student awareness and interest in managed care pharmacy, and he is engaged in community outreach. He was also commended for being both personable and professional.

Sarah Milkovich was the April 2013 Student of the Month.

She showed leadership and professionalism in planning the Mr. PharmD pageant, which raised over $1100 for the Make-A-Wish foundation. Sarah‟s efforts drew together pharmacy students, students from outside the college, parents and siblings, faculty, and others from the surrounding community. In addition to her role in this event, Sarah is also vice-president of the American Pharmacists Association – Academy of Student Pharmacists; she was very involved in coordinating the patient counseling competition at UT. The Student of the Month award will continue to be awarded during the 2013-2014 academic year, offering the opportunity to recognize the efforts and service of several more of the college‟s outstanding students.

Upcoming Events PROFESSIONAL ADVANCEMENT CEREMONY Friday, August 16, 2013 at 4:30 PM in Nitschke Auditorium on Main Campus The college welcomes its 2013 P1 class to the professional division in this annual ceremony.

HOMECOMING 2013 October 4-6 The events include the annual Homecoming Gala, the College of Pharmacy and Pharmaceutical Sciences Alumni Affiliate luncheon, and the Sunday CE session. The Rockets face off against Western Michigan in the Glass Bowl at 3pm.

P4 Student wins ASHP Student Leadership Award Abby Rabatin, a P4 pharmacy student, was among eleven pharmacy students nationwide who were recently recognized by the American Society of Health-System Pharmacists (ASHP) for their achievement in health-system pharmacy practice and campus leadership with the ASHP Student Leadership Award.

The award, sponsored by ASHP and the ASHP Research and Education Foundation, is given to student members in their second through fourth professional years of pharmacy school. The award winners receive a plaque, an ASHP drug information reference library, and a $2,500 cash award.

ASHP is the national professional organization whose 40,000 members include pharmacists, pharmacy technicians, and pharmacy students who provide patient care services in hospitals, health systems, and ambulatory clinics. For 70 years, the Society has been on the forefront of efforts to improve medication use and enhance patient safety.

Leadership Appointments continued from page 1 Pharmaceutical Sciences encompass six curricula inclusive of the PhD in Medicinal Chemistry and the PhD in Experimental Therapeutics, the latter of which will enroll its inaugural learners in August 2013.

among those who founded the Doctor of Pharmacy program, for which the pharmacy and pharmaceutical sciences industries have a high and sustained affinity.

Assistant Dean for Academic Affairs

Department Chair, Medicinal Biological Chemistry

and

Laurie Mauro, PharmD has been appointed to the position of assistant dean for Academic Affairs. This position, which is new to the college, focuses on addressing accreditation standards and assessment. Dr. Mauro has ably led the college‟s assessment program, which guides improvement of the college‟s 12 distinct curricula.

Dr. Mauro‟s experience also includes her role as a critical care practitioner.

Dr. Mauro is one of two clinicians hired in 1985 to spearhead the clinical training of pharmacists in the former Medical College Hospital. She was

The Department of Medicinal Chemistry is now chaired by Katherine Wall, PhD, professor of Medicinal and Biological Chemistry, following the appointment of former chair, Dr. Marcia McInerney, to associate dean for Research and Graduate Studies. Dr. Wall, who was the vice chair of the department, will lead the department for a fixed term of three years. Highly regarded for her funded research in cytokines in myasthenia gravis, and currently NIH funded for research in GlycopeptideBased Cancer Antigen Vaccines and CD38 and NAD Metabolites in

Lymphocyte Signaling, she brings to the role of chair her rich and vibrant leadership experience. Dr. Wall presided over the graduate program in the Department of Medicinal and Biological Chemistry and currently directs the college‟s Honors program.

Vice Chair, Department of Medicinal and Biological Chemistry Hermann von Grafenstein, PhD, MD will have primary responsibility for the graduate program in medicinal chemistry during his three-year term. The graduate program entails the college‟s oldest PhD degree program, the MS degree and the inaugural BS in Pharmaceutical Sciences/MS in Medicinal Chemistry program. Dr. von Grafenstein‟s research is in immunology and structural biochemistry.

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