Appendices Annual Report 2015
Annual Report 2015 - Appendices
Appendices 1.
Scientific input ..................................................................................................................................................................... 2
3.
Scientific output ................................................................................................................................................................ 14
2. 4. 5. 6.
Newly started PhD projects in 2015 ......................................................................................................................... 12 Marks of recognition from peers and societal groups ...................................................................................... 79 A. B.
Demonstrable use of research products by peers and by societal groups ................................ 98
Research products for peers and societal target groups and outreach activities ................109
Acquisition per type of funding ...............................................................................................................................122
1
Annual Repprt 2015 - Appendices
Appendix 1: Scientific input Funding type (gs): 2 is NWO/KNAW funded research, 3 is project funding from non-profit, ministries, FES & EU, and 4 is based on a mix of contract-research (for profit/industry) and donations/philanthropy.
Brain Imaging Technology Name Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students
Barkhof Boellaard Boer Groot Gunst Iannuzzi Lammertsma Mansvelder Peterman Stam Veltman Verdaasdonk Windhorst Wuite Molthoff Munck Bijma Pouwels Toonen Vrenken Vugts Werf Kuzmin Adriaanse Adriaanse Amiri Doumari Beaino Berckel Bie Cheng Cover Demuru Eersels Gerrits Heuvel Heuvel Hillebrand Hofman Huisman Kuijer Liu Steenwijk Yaqub Avramiea Bartel Filp Gerrits Golla Janssen Kloet Mansor Nissen Raaphorst Visser Wildt
Department F. R. J. M.L. M.C.M. D. A.A. H.D. E.J.G. C.J. D.J. R.M. A.D. G. C.F.M. J.C. F. P.J.W. R.F.G. H. D.J. Y.D. N S.M. S.M. H. W. B.N.M. H.M.A. J.C. K.S. M. J.L.H. N.J.H.M. O.A. O.A. A. M.B.M. M.C. J.P.A. Y. M.D. M A.E. F. U.R. N.J.H.M. S.V.S. B. S. M.S.B. I.A. R.M. M. B.
de de
de
van der
van de
van den van den
de
van der
2
VUmc, Radiology VUmc, Nuclear Medicine FEW, Physics of Life and Health FEW, Physics of Life and Health FEW, Mathematics FEW, Physics of Life and Health VUmc, Nuclear Medicine FALW, Integrative FEW, Physics of Life and Health VUmc, Neurology Psychiatry GGZ inGeest VUmc, Physics and Medical VUmc, Nuclear Medicine FEW, Physics of Life and Health VUmc, Nuclear Medicine VUmc, Physics and Medical FEW, Mathematics VUmc, Physics and Medical FALW, Functional Genomics VUmc, Physics and Medical VUmc, Nuclear Medicine VUmc, Anatomy and FEW, Physics of Life and Health VUmc, Nuclear Medicine VUmc, Nuclear Medicine VUmc, Physics and Medical VUmc, Nuclear Medicine VUmc, Nuclear Medicine VUmc, Paediatrics VUmc, Nuclear Medicine VUmc, Physics and Medical VUmc, Neurology VUmc, Nuclear Medicine VUmc, Anatomy and VUmc, Psychiatry VUmc, Psychiatry VUmc, Neurology VUmc, Physics and Medical VUmc, Nuclear Medicine VUmc, Physics and Medical VUmc, Radiology VUmc, Physics and Medical VUmc, Nuclear Medicine FALW, Integrative VUmc, Physics and Medical VUmc, Nuclear Medicine VUmc, Anatomy and VUmc, Nuclear Medicine VUmc, Radiology FALW, Integrative VUmc, Nuclear Medicine VUmc, Neurology VUmc, Nuclear Medicine VUmc, Physics and Medical VUmc, Nuclear Medicine
Funding type 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 3 1 1 1 2 1 3 4 1 1 1 2 2 1 3 1 1 2 1 1 1 1 3 4 1 2 2 3 1 3 3 2 3 3 3 3 4
fte 0,10 0,19 0,20 0,20 0,07 0,10 0,20 0,05 0,10 0,20 0,20 0,05 0,30 0,10 0,05 0,40 0,15 0,20 0,14 0,40 0,30 0,21 0,50 0,37 0,23 0,00 0,25 0,10 0,00 0,33 0,30 0,58 0,20 0,58 0,10 0,10 0,20 0,08 0,10 0,15 0,50 0,25 0,15 0,28 0,75 0,75 0,31 0,75 0,75 0,69 0,01 0,75 0,75 0,50 0,75
Annual Report 2015 - Appendices
Brain Mechanisms in Health & Disease Name
Department
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Barkhof Blankenstein Gunst Heutink Jonge Knaap Lambalk Mansvelder
F. M.A. M.C.M. P. R. M.S. C.B. H.D.
Tenured staff Tenured staff Tenured staff
Posthuma Salomons Smit
D. G.S. A.B.
Tenured staff
Spijker
S.
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Verhage Verhage Verhage Verhage Wiel Posthuma Wiel
M. M. M. M. M.A. D. M.A.
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Abbink Bochdanovits Groffen Heine Jonker
G.E.M. Z. A.J.A. V.M. M.A.
Tenured staff
Kesteren
R.E.
van
Tenured staff
Kock
C.
de
Tenured staff
Li
K.W.
Tenured staff
K.
Tenured staff
LinkenkaerHansen Meredith
Tenured staff
Pouwels
P.J.W.
Tenured staff Tenured staff Tenured staff
Stiedl Toonen Verheijen
R.O. R.F.G. M.H.G.
Tenured staff
Wieringen
W.N.
van
Tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff
Wieringen BonouvriĂŠ Brink Broeke Bugiani Bugiani Cornelisse Das
W. L.A. H.J. J.H.P. M. M. L.N. S.
van der
Non-tenured staff Non-tenured staff Non-tenured staff
Dominguez Reyes Farina Hardstone
N. M. R.E.
de de van der
van der van de
R.M.
ten
3
VUmc, Radiology VUmc, Clinical Chemistry FEW, Mathematics VUmc, Clinical Genetics VUmc, Clinical Chemistry VUmc, Child Neurology VUmc, Reproductive Medicine FALW, Integrative Neurophysiology FALW, Complex Trait Genetics VUmc, Clinical Chemistry FALW, Molecular and Cellular Neurobiology FALW, Molecular and Cellular Neurobiology FALW, Functional Genomics FALW, Functional Genomics VUmc, Clinical Genetics VUmc, Clinical Genetics FEW, Mathematics VUmc, Clinical Genetics VUmc, Epidemiology and Biostatistics VUmc, Child Neurology VUmc, Clinical Genetics VUmc, Clinical Genetics VUmc, Child Neurology VUmc, Epidemiology and Biostatistics FALW, Molecular and Cellular Neurobiology FALW, Integrative Neurophysiology FALW, Molecular and Cellular Neurobiology FALW, Integrative Neurophysiology FALW, Integrative Neurophysiology VUmc, Physics and Medical Technology FALW, Functional Genomics FALW, Functional Genomics FALW, Molecular and Cellular Neurobiology VUmc, Epidemiology and Biostatistics FEW, Mathematics VUmc, Rehabilitation Medicine VUmc, Clinical Chemistry VUmc, Clinical Genetics VUmc, Child Neurology VUmc, Child Neurology VUmc, Clinical Genetics FALW, Integrative Neurophysiology VUmc, Clinical Genetics VUmc, Clinical Genetics FALW, Integrative Neurophysiology
Funding type 1 1 1 1 1 1 1 2
fte
2 1 1
0,25 0,40 0,20
1
0,30
1 3 1 2 1 1 1
0,11 0,03 0,01 0,04 0,03 0,50 0,00
1 1 1 2 1
0,50 0,75 0,40 1,00 0,13
1
0,25
1
0,50
1
0,35
1
0,50
1
0,50
1
0,15
1 1 1
0,20 0,26 0,50
1
0,00
1 1 1 1 1 4 1 3
0,02 0,25 0,00 0,50 0,33 0,33 0,40 0,30
2 4 2
0,53 0,22 0,13
0,10 0,04 0,07 0,01 0,03 0,60 0,30 0,05
Annual Repprt 2015 - Appendices
Non-tenured staff
Heistek
T.
Non-tenured staff
Klaassen
R.V.
Non-tenured staff Non-tenured staff
Klok Kortleven
M.D. C.A.
Non-tenured staff Non-tenured staff
Leeuw Luccicchi
C.A. A.
Non-tenured staff Non-tenured staff
Meijer Mnie Filalie
M. O.
Non-tenured staff
Nierop
P.
Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff PhD student PhD student PhD students
Nรถlle Nota Peters Scheper Sluis Smith Sniekers Spaendonk Stringer Struijs Taskesen Taskesen Trotsenburg Voorn Wamelink Weering Wit Wolf Aflakparast Aflakparast Agra de Almeida Quadros Arora Badia Soteras
A. B. H.E. W. S. D.E.C. S. R.M.L. S. E.A. E. E. M.A.A. J.P. M.M.C. J.R.T. H. N.I. M. M. A.R.
C.
PhD students PhD students PhD students PhD students PhD students
Berenguer Escuder Bourgeois Brouwer Brouwers Brouwers Bruinsma
PhD students PhD students PhD students
Buttler Cerveira Cetereisi
R.M. T. D.
PhD students PhD students
Classen Deijk
J.A. A
PhD students PhD students
Diez Arazola Doreswamy
R. K.K.
PhD students
Dubey
M.
PhD students PhD students PhD students PhD students PhD students
Dubey Emperado Melero Erbrink Farzana Farzana
M. J. R.M. F. F.
PhD students PhD students PhD students
de
van
van der
van
van van der van de
S. A
Q.T. M. E. E. B.
van
4
FALW, Integrative Neurophysiology FALW, Molecular and Cellular Neurobiology VUmc, Child Neurology FALW, Integrative Neurophysiology FALW, Complex Trait Genetics FALW, Integrative Neurophysiology VUmc, Clinical Genetics FALW, Integrative Neurophysiology FALW, Molecular and Cellular Neurobiology VUmc, Clinical Genetics VUmc, Clinical Chemistry VUmc, Reproductive Medicine VUmc, Clinical Genetics VUmc, Clinical Genetics VUmc, Clinical Chemistry FALW, Complex Trait Genetics VUmc, Clinical Genetics FALW, Complex Trait Genetics VUmc, Clinical Chemistry FALW, Complex Trait Genetics VUmc, Clinical Genetics VUmc, Gynaecology VUmc, Pathology VUmc, Clinical Chemistry VUmc, Clinical Genetics VUmc, Clinical Genetics VUmc, Child Neurology FEW, Mathematics FEW, Mathematics FALW, Functional Genomics
2
0,90
1
0,90
1 2
1,00 0,90
2 2
0,30 0,90
1 3
0,60 0,90
1
0,90
3 3 4 1 2 1 3 1 2 1 2 3 1 1 1 1 3 1 1 2 3
0,45 0,04 0,38 0,20 0,72 0,20 0,23 0,10 0,90 0,60 0,23 0,22 0,00 0,10 0,20 0,60 0,40 0,30 0,35 0,03 0,25
FALW, Functional Genomics FALW, Molecular and Cellular Neurobiology FALW, Molecular and Cellular Neurobiology FALW, Functional Genomics VUmc, Clinical Genetics VUmc, Child Neurology VUmc, Child Neurology FALW, Integrative Neurophysiology VUmc, Clinical Chemistry FALW, Functional Genomics FALW, Molecular and Cellular Neurobiology FALW, Functional Genomics FALW, Molecular and Cellular Neurobiology FALW, Functional Genomics FALW, Integrative Neurophysiology FALW, Integrative Neurophysiology VUmc, Child Neurology FALW, Functional Genomics VUmc, Clinical Genetics FALW, Functional Genomics FALW, Functional Genomics
3 3
0,75 0,18
3
0,56
3 1 1 2 2
0,30 0,75 0,37 0,38 0,75
4 3 3
0,31 0,75 0,75
3 2
0,13 0,30
4 3
0,06 0,75
2
0,19
3 1 1 1 3
0,56 0,75 0,75 0,19 0,06
Annual Report 2015 - Appendices
PhD students
A.
PhD students PhD students
Geeyarpuram Nadadhur Geytenbeek Haan
PhD students PhD students PhD students PhD students PhD students
Hamilton Hammerschlag He He Heldring
E.M.C. A. E. E. C
PhD students PhD students PhD students PhD students PhD students
Hinz Hoekstra Holmes Huson Irrmischer
L. S.D. D. V.W.J. M.
PhD students PhD students PhD students PhD students
Jansen Kedar Keimpema Kerkhofs
A.G. G.H. L. A.
PhD students PhD students PhD students PhD students
S.H.G. F.T.W. F.T.W. J.
PhD students
Kevelam Koopmans Koopmans KovacevicDivljakovic Kramvis
PhD students
Kroon
T.
PhD students PhD students
Leferink Lenselink
P.S. M
PhD students PhD students
Mancini Mohan
R. H.
PhD students PhD students PhD students
Moro Nagel Negrean
A. M. A.
PhD students
Obermaijer
J.M.G.
PhD students
Pandya
N.J.
PhD students PhD students PhD students PhD students
Persoon Rappard Sigurdsson Silva Dias Pires
C.M. D.F. S.V. J.
PhD students
Simpraga
S.
PhD students
Terra
H.
PhD students PhD students PhD students PhD students PhD students
Vazquez Sanchez Vroom Wiersma Wisse Ziel
S. C. V.I. L.E. A.M.
J.J.M. R.
de
van
I.
van
van
5
FALW, Functional Genomics
3
0,75
VUmc, Rehabilitation Medicine FALW, Integrative Neurophysiology VUmc, Child Neurology FALW, Complex Trait Genetics FALW, Functional Genomics FALW, Functional Genomics FALW, Molecular and Cellular Neurobiology FALW, Complex Trait Genetics FALW, Complex Trait Genetics VUmc, Child Neurology VUmc, Clinical Genetics FALW, Integrative Neurophysiology FALW, Complex Trait Genetics FALW, Functional Genomics FALW, Functional Genomics FALW, Integrative Neurophysiology VUmc, Child Neurology FALW, Functional Genomics FALW, Functional Genomics FALW, Functional Genomics
3 2
0,03 0,75
3 3 1 3 3
0,56 0,75 0,38 0,38 0,75
3 2 3 1 2
0,75 0,75 0,75 0,75 0,75
2 3 3 3
0,31 0,44 0,75 0,75
2 2 3 3
0,75 0,25 0,50 0,75
FALW, Integrative Neurophysiology FALW, Integrative Neurophysiology VUmc, Child Neurology FALW, Molecular and Cellular Neurobiology FALW, Functional Genomics FALW, Integrative Neurophysiology VUmc, Clinical Genetics VUmc, Clinical Genetics FALW, Integrative Neurophysiology FALW, Integrative Neurophysiology FALW, Molecular and Cellular Neurobiology VUmc, Clinical Genetics VUmc, Child Neurology VUmc, Clinical Genetics FALW, Integrative Neurophysiology FALW, Integrative Neurophysiology FALW, Integrative Neurophysiology FALW, Functional Genomics VUmc, Clinical Genetics VUmc, Clinical Genetics VUmc, Child Neurology VUmc, Clinical Genetics
3
0,75
2
0,75
2 2
0,75 0,75
3 3
0,75 0,75
1 2 2
0,75 0,75 0,75
3
0,75
3
0,75
2 3 2 3
0,60 0,60 0,16 0,75
3
0,75
2
0,75
3 2 2 2 2
0,75 0,75 0,15 0,75 0,38
Annual Repprt 2015 - Appendices
Neurodegeneration Name
Department
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Barkhof Berendse Blankenstein Flier Groenewegen
F. H.W. M.A. W.M. H.J.
Tenured staff Tenured staff Tenured staff Tenured staff
Heutink Jonge Lammertsma Mansvelder
P. R. A.A. H.D.
Tenured staff Tenured staff Tenured staff
Rozemuller Scheltens Smit
A.J.M. P. A.B.
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Stam Swieten Vies Weinstein Drukarch
C.J. J.C. S.M. H. B.
Tenured staff Tenured staff Tenured staff
Flier Teunissen Voorn
W.M. C.E. P.
Tenured staff
Wouterlood
F.G.
Tenured staff
Berg
W.D.J.
van de
Tenured staff
Dam
A.M.W.
van
Tenured staff
Heuvel
O.A.
van den
Tenured staff Tenured staff Tenured staff Tenured staff
Holstege Hoozemans Hoozemans Kesteren
H. J.J.M. J.J.M. R.E.
Tenured staff
Li
K.W.
Tenured staff
Vrenken
H.
Tenured staff
Werf
Y.D.
Tenured staff
Wilhelmus
M.M.M.
Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff
Adriaanse Assema Beek Berckel Braber Del Campo Milan Dijk Farina Foncke Groot Haan Hooghiemstra Kester Lemstra Mishra
S.M. D.M.E. J.H.G.M. B.N.M. A. M. K.D. M. E.M.J. M. W. A.M. M.I. A.W. A.
van der
de
van van der
van der
van
van der
van van van den van
de de
6
VUmc, Radiology VUmc, Neurology VUmc, Clinical Chemistry VUmc, Neurology VUmc, Anatomy and Neurosciences VUmc, Clinical Genetics VUmc, Clinical Chemistry VUmc, Nuclear Medicine FALW, Integrative Neurophysiology VUmc, Pathology VUmc, Neurology FALW, Molecular and Cellular Neurobiology VUmc, Neurology VUmc, Clinical Genetics VUmc, Pathology VUmc, Neurology VUmc, Anatomy and Neurosciences VUmc, Neurology VUmc, Clinical Chemistry VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Clinical Genetics VUmc, Pathology VUmc, Pathology FALW, Molecular and Cellular Neurobiology FALW, Molecular and Cellular Neurobiology VUmc, Physics and Medical Technology VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Nuclear Medicine VUmc, Neurology VUmc, Clinical Genetics VUmc, Nuclear Medicine VUmc, Neurology VUmc, Clinical Chemistry VUmc, Neurology VUmc, Clinical Genetics VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology FALW, Complex Trait Genetics
Funding type 1 1 1 1 1
fte
1 1 1 1
0,01 0,05 0,15 0,05
1 1 1
0,20 0,40 0,10
1 1 1 1 1
0,20 0,20 0,50 0,00 0,50
1 1 1
0,70 0,40 0,50
1
0,20
1
0,80
1
0,20
1
0,10
1 1 3 1
1,00 0,30 0,50 0,25
1
0,05
3
0,20
1
0,29
1
0,90
1 3 1 1 3 3 1 4 1 3 3 3 3 3 3
0,15 0,00 0,40 0,30 0,83 1,00 0,00 0,23 0,30 0,12 0,35 1,00 0,18 0,38 0,90
0,20 0,30 0,09 0,10 0,10
Annual Report 2015 - Appendices
Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students
Mulder Nรถlle Ossenkoppele Pijnenburg Prins Scheper Sikkes Staekenborg Straaten Swieten Tijms Veerhuis Verwey Visser Visser Vlies Vriend Wilde Beker Benedictus Bertens Boon Dhingra Duits Engels Ganz
S.D. A. R. Y.A.L. N.D. W. S.A.M. S.S. E.C.W. J.C. B.M. R. N.A. M.C. P.J. A.E. C. A. N. M.R. D. B.D.C. A. F.H. M.M.A. A
PhD students PhD students
Haan Hijazi
J. S
PhD students PhD students PhD students
Hokke Hondius Jager
P.E. D.C. A.M.
PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students
Jansen Kate Konijnenberg Krudop Leeuwis Legdeur Leijenaar Loenhoud Louwersheimer Maurik Moors
I.E. M. E. W.A. A.E. N. J.F. A.C. E. I.S. T.
PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students PhD students
Oort Orasji Pike Rhodius-Meester Rosenberger Scheltens Slot Snkhchyan Spek
Q. S.S.S.M. A.F. H.F.M. A. N.M.E. R.E.R. H. S.J.F.
PhD students PhD students PhD students
Steenoven Timmers Tolboom
I. T. S.
van
PhD students
Veij Mestdagh
C
de
PhD students PhD students PhD students
Verfaillie Vermunt Wiersma
S.C.J. L. V.I.
van van
van der de
den
de ten
van van
van der
7
VUmc, Clinical Chemistry VUmc, Clinical Genetics VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Clinical Genetics VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Clinical Chemistry VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Clinical Genetics VUmc, Neurology VUmc, Neurology FALW, Molecular and Cellular Neurobiology VUmc, Neurology FALW, Molecular and Cellular Neurobiology VUmc, Clinical Genetics VUmc, Pathology VUmc, Anatomy and Neurosciences VUmc, Clinical Genetics VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Anatomy and Neurosciences VUmc, Neurology VUmc, Neurology VUmc, Clinical Chemistry VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Neurology VUmc, Pathology FALW, Molecular and Cellular Neurobiology VUmc, Neurology VUmc, Neurology FALW, Molecular and Cellular Neurobiology FALW, Molecular and Cellular Neurobiology VUmc, Neurology VUmc, Neurology VUmc, Clinical Genetics
3 3 3 1 3 4 3 3 1 3 3 1 3 1 2 3 3 3 3 3 3 3 3 3 3 4
1,00 0,45 0,75 0,30 0,80 0,20 0,50 0,25 0,20 0,00 0,33 0,70 0,35 0,10 0,30 1,00 1,00 0,75 0,31 0,75 0,75 0,25 0,69 0,75 0,75 0,25
3 3
0,75 0,75
1 3 1
0,20 0,75 0,03
3 3 3 3 3 3 3 3 3 3 3
0,75 0,75 0,75 0,31 0,75 0,69 0,53 0,75 0,75 0,38 0,75
3 3 3 3 2 3 3 3 2
0,31 0,75 0,25 0,75 0,75 0,75 0,75 0,66 0,75
3 3 2
0,53 0,56 0,24
4
0,25
3 3 2
0,75 0,53 0,16
Annual Repprt 2015 - Appendices
PhD students PhD students
Willemse Zwan
E.A.J. M.D.
VUmc, Clinical Chemistry VUmc, Neurology
3 2
0,62 0,75
Department
Funding type 1 1 1 1 1
fte
1 1 1 1 1 1 1
0,10 0,40 0,20 0,20 0,60 0,80 0,10
3 1 1
0,85 0,25 0,60
2
1,00
1
0,15
1
0,10
3 1
0,20 0,20
3 3
0,00 0,90
1 1 3
0,89 0,40 0,17
3
0,83
3 1
1,00 0,04
3
0,60
3 1 3 3
0,25 0,20 0,10 0,50
1
1,00
3 4
0,44 0,25
4 1 1 3 3 2
0,37 0,20 0,20 0,38 0,50 0,75
Neuroinflammation Name Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Barkhof Castelijns Dijkstra Elsen Geurts
F. J.A. C.D. P.J. J.J.G.
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Kooijk Polman Uitdehaag Valk Vries Amor Drukarch
Y. C.H. B.M.J. P. H.E. S. B.
van
Tenured staff Tenured staff Tenured staff
Horssen Teunissen Dam
J. C.E. A.M.W.
van
Tenured staff
Douw
L.
Tenured staff
Pouwels
P.J.W.
Tenured staff
Vrenken
H.
Non-tenured staff Non-tenured staff
Bechten Dijk
A.K. B.W.
Non-tenured staff Non-tenured staff
Groeneveld Hulst
G.J. H.E.
Non-tenured staff Non-tenured staff Non-tenured staff
Kamphuis Killestein Klauser
W.W. J. A.M.
Non-tenured staff
Klaver
R.
Non-tenured staff Non-tenured staff
Kooij Linden
G. F.A.H.
Non-tenured staff
Mokkink
L.B.
Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff
Nijland Oosten Petzold Schenk
P.G. B.W. A.F.S. G.J.
Non-tenured staff
Schoonheim
M.M.
Non-tenured staff Non-tenured staff
Sonder Steenwijk
J.M. M.D.
Non-tenured staff Non-tenured staff Non-tenured staff PhD students PhD students PhD students
Strijbis Verbraak Wattjes Balk Burggraaff Chakraborty
E.M.M. F.D. M.P. L.J. J. A.
van den
van der de
van
van
van der
van
8
VUmc, Radiology VUmc, Radiology VUmc, Molecular Cell Biology VUmc, Pathology VUmc, Anatomy and Neurosciences VUmc, Molecular Cell Biology VUmc, Neurology VUmc, Neurology VUmc, Pathology VUmc, Molecular Cell Biology VUmc, Pathology VUmc, Anatomy and Neurosciences VUmc, Molecular Cell Biology VUmc, Clinical Chemistry VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Physics and Medical Technology VUmc, Physics and Medical Technology VUmc, Radiology VUmc, Physics and Medical Technology VUmc, Neurology VUmc, Anatomy and Neurosciences VUmc, Molecular Cell Biology VUmc, Neurology VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Molecular Cell Biology VUmc, Epidemiology and Biostatistics VUmc, Epidemiology and Biostatistics VUmc, Molecular Cell Biology VUmc, Neurology Vumc, Ophthalmology VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Neurology VUmc, Physics and Medical Technology VUmc, Neurology Vumc, Ophthalmology VUmc, Radiology VUmc, Neurology VUmc, Neurology VUmc, Molecular Cell Biology
0,20 0,20 0,40 0,10 0,80
Annual Report 2015 - Appendices
PhD students
Chrobok
N.
PhD students PhD students PhD students PhD students PhD students
Coric Daams Dekker Derada Troletti Derks
D. M. I. C. J.M.M.
PhD students
Eijlers
A.J.C.
PhD students
Espitia Pinz贸n
N.
PhD students
Geest
Q.
PhD students PhD students
Hagens Jonkman
M.H.J. L.E.
PhD students PhD students
Kamermans Kiljan
A. S.
PhD students
Klaver
R.
PhD students PhD students PhD students
Leurs Malekzadeh Meijer
C.E. A. K.A.
PhD students PhD students PhD students
Nij Bijvank Peferoen Sestito
J.A. L.A.N. C.
PhD students PhD students PhD students PhD students PhD students
Steenwijk Tewarie Vogel Wijburg Wit
M.D. P.K. D.Y.S. M.T. N.M.
van
de
VUmc, Anatomy and Neurosciences VUmc, Neurology VUmc, Radiology VUmc, Radiology VUmc, Molecular Cell Biology VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Neurology VUmc, Anatomy and Neurosciences VUmc, Molecular Cell Biology VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Neurology VUmc, Clinical Chemistry VUmc, Anatomy and Neurosciences Vumc, Ophthalmology VUmc, Pathology VUmc, Anatomy and Neurosciences VUmc, Radiology VUmc, Neurology VUmc, Molecular Cell Biology VUmc, Neurology VUmc, Molecular Cell Biology
2
0,75
3 3 3 2 3
0,56 0,10 0,38 0,75 0,75
3
0,69
3
0,05
3
0,75
3 3
0,75 0,75
3 3
0,75 0,50
3
0,12
3 3 3
0,75 0,28 0,75
3 3 2
0,62 0,75 0,75
3 3 3 3 2
0,19 0,49 0,13 0,75 0,75
Department
Funding type 1 3 1 3 1 1 1 1 1 1 2
fte
1 1
0,40 0,00
1
0,20
1 1
0,20 0,20
1 1 1
0,20 0,02 0,10
Neurobiology of Mental Health Name Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff
Bartels, M. Bartels, M. Boomsma, D.I. Boomsma, D.I. Dolan, C.V. Geus, E.J.C. de Gunst Heutink Klein Lammertsma Mansvelder
M. M. D.I. D.I. C.V. E.J.C. M.C.M. P. M. A.A. H.D.
Tenured staff Tenured staff
Penninx Schoffelmeer
B.W.J.H. A.N.M.
Tenured staff
Smit
A.B.
Tenured staff Tenured staff
Smit Spijker
J.H. S.
Tenured staff Tenured staff Tenured staff
Veltman Wiel Drukarch
D.J. M.A. B.
den de
van der
9
FGB, Biological Psychology FGB, Biological Psychology FGB, Biological Psychology FGB, Biological Psychology FGB, Biological Psychology FGB, Biological Psychology FEW, Mathematics VUmc, Clinical Genetics VUmc, Medical Psychology VUmc, Nuclear Medicine FALW, Integrative Neurophysiology VUmc, Psychiatry VUmc, Anatomy and Neurosciences FALW, Molecular and Cellular Neurobiology Psychiatry GGZ inGeest FALW, Molecular and Cellular Neurobiology Psychiatry GGZ inGeest FEW, Mathematics VUmc, Anatomy and Neurosciences
0,15 0,15 0,13 0,12 0,35 0,15 0,06 0,01 0,15 0,05 0,05
Annual Repprt 2015 - Appendices
Tenured staff Tenured staff Tenured staff
Koellinger Middeldorp, C.M. Pattij
P.D. C.M. T.
Tenured staff Tenured staff
Vink, J.M. Voorn
J.M. P.
Tenured staff
Vries
T.J.
Tenured staff
Diergaarde
L.
Tenured staff Tenured staff Tenured staff
Ent van 't, D. Gerritsen Heuvel
D. L. O.A.
Tenured staff Tenured staff
Lamers Li
F. K.W.
Tenured staff Tenured staff Tenured staff Tenured staff Tenured staff Non tenured staff Non-tenured staff Non-tenured staff
Polderman Schmaal Smit, D.J.A. Smit, D.J.A. Wieringen Abdellaoui, A. Arwert Bet
J.C. L. D.J.A. D.J.A. W. A. L.I. P.M.
Non-tenured staff Non tenured staff Non-tenured staff Non-tenured staff Non-tenured staff
Bot Draisma, H.H.M. Drent Exel Goriounova
M. H.H.M. M.L. E. N.A.
Non-tenured staff Non-tenured staff Non-tenured staff Non tenured staff Non-tenured staff Non tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non tenured staff Non-tenured staff
Heuvel Heuvel Hoogendoorn Hottenga, J.J. Jansen Kan, K.J. Klumpers Koene Marle Micha Milaneschi Nivard, M.G. Oever
O.A. O.A. A.W. J.J. R. K.J. U.M.H. T. H. D. Y. M.G. M.C.
Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff Non-tenured staff
Oostrom Ouwendijk Reuling Rotteveel Sistermans Someren Thomaes Veerhuis Veltman
K.J. M. I.E.W. J. E.A. E.J.W. K. R. D.J.
Non tenured staff Non-tenured staff Non-tenured staff PhD student PhD student PhD students PhD students PhD students
Verweij, C.J.H. Vriend Weissenbruch Aflakparast Aflakparast Bloemendaal Boedhoe Brรถring
C.J.H. C. M.M. M. M. L. P.S. T.
de
van 't van den
van der
van
van den van den
van
van den
van
van
van
10
FALW, Complex Trait Genetics FGB, Biological Psychology VUmc, Anatomy and Neurosciences FGB, Biological Psychology VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences VUmc, Anatomy and Neurosciences FGB, Biological Psychology VUmc, Psychiatry VUmc, Anatomy and Neurosciences VUmc, Psychiatry FALW, Molecular and Cellular Neurobiology FALW, Complex Trait Genetics VUmc, Psychiatry FGB, Biological Psychology FGB, Biological Psychology FEW, Mathematics FGB, Biological Psychology VUmc, Endocrinology VUmc, Clinical Pharmacology and Pharmacy Psychiatry GGZ inGeest FGB, Biological Psychology VUmc, Endocrinology VUmc, Psychiatry FALW, Integrative Neurophysiology VUmc, Psychiatry VUmc, Psychiatry Psychiatry GGZ inGeest FGB, Biological Psychology VUmc, Psychiatry FGB, Biological Psychology Psychiatry GGZ inGeest VUmc, Medical Psychology Psychiatry GGZ inGeest VUmc, Clinical Genetics VUmc, Psychiatry FGB, Biological Psychology FALW, Molecular and Cellular Neurobiology VUmc, Medical Psychology VUmc, Medical Psychology VUmc, Medical Psychology VUmc, Endocrinology-Children VUmc, Clinical Genetics VUmc, Medical Psychology Psychiatry GGZ inGeest Psychiatry GGZ inGeest VUmc, Anatomy and Neurosciences FGB, Biological Psychology VUmc, Psychiatry VUmc, Neonatology FEW, Mathematics FEW, Mathematics VUmc, Endocrinology VUmc, Psychiatry VUmc, Medical Psychology
3 1 1
0,17 0,4 0,70
3 1
0,3 0,10
1
0,60
1
0,10
1 2 1
0,4 0,50 0,10
2 1
0,20 0,10
1 1 1 3 1 3 1 1
0,40 1,00 0,3 0,3 0,03 0,80 0,20 0,10
2 3 1 1 3
0,20 0,8 0,80 0,10 0,72
1 2 1 1 2 1 1 3 1 3 1 2 2
0,10 0,10 0,20 0,4 1,00 0,5 0,20 0,06 0,20 0,00 0,50 0,8 0,90
3 3 3 1 1 1 1 1 1
0,20 0,20 0,06 0,05 0,10 0,20 0,20 0,30 0,00
3 3 1 1 2 4 3 3
0,3 0,40 0,10 0,34 0,03 0,50 0,75 0,00
Annual Report 2015 - Appendices
PhD students
Carr
M.R.
PhD students PhD students PhD students
Chavarria-Siles Dinga Fan
I.M. R. S.
PhD students
Gonzalez Lozano
M.A.
PhD students PhD students PhD students PhD students PhD students
Gossink Grootheest Hu Karlsson Linner Koskinen
F.T. G. X. R. M.
PhD students PhD students PhD students
Kulve Linthorst Marchisella
J.S. J. E.
PhD students PhD students PhD students PhD students PhD students
S.F.W. C.C. M.L. W. M.
PhD students
Meddens Minica, C.C. Oudega Peyrot Raimundo Pinto de Matos Riga
PhD students
Rosato
M.
PhD students PhD students
Rutten Schmitz
S. L.J.M.
PhD students PhD students PhD students PhD students PhD students
Straver Swagerman, S.C. Varsseveld Velzen Vries
R. S.C. N.C. L. F.E.
van van de
PhD students PhD students PhD students
Vries Wit Ziel
F.E. S.J. A.M.
de de van
VUmc, Anatomy and Neurosciences FALW, Complex Trait Genetics VUmc, Psychiatry VUmc, Anatomy and Neurosciences FALW, Molecular and Cellular Neurobiology Psychiatry GGZ inGeest Psychiatry GGZ inGeest VUmc, Psychiatry FALW, Complex Trait Genetics FALW, Molecular and Cellular Neurobiology VUmc, Endocrinology VUmc, Clinical Genetics FALW, Molecular and Cellular Neurobiology FALW, Complex Trait Genetics FGB, Biological Psychology Psychiatry GGZ inGeest Psychiatry GGZ inGeest FALW, Molecular and Cellular Neurobiology FALW, Molecular and Cellular Neurobiology FALW, Molecular and Cellular Neurobiology Psychiatry GGZ inGeest FALW, Molecular and Cellular Neurobiology VUmc, Clinical Genetics FGB, Biological Psychology VUmc, Endocrinology Psychiatry GGZ inGeest VUmc, Anatomy and Neurosciences Psychiatry GGZ inGeest VUmc, Psychiatry VUmc, Clinical Genetics
ten
D.
11
3
0,75
2 3 3
0,38 0,38 0,00
3
0,75
2 1 1 3 3
0,50 0,40 0,50 0,25 0,75
4 1 1
0,38 0,75 0,75
3 3 2 1 3
0,25 0,85 0,20 0,50 0,75
2
0,75
3
0,75
2 3
0,20 0,75
3 2 4 2 3
0,75 0,57 0,75 0,50 0,00
2 3 2
0,20 0,20 0,37
Annual Repprt 2015 - Appendices
Appendix 2: Newly started PhD projects 2015 PhD student
Department
Avramiea, A.E.
Integrative Neurophysiology
Badia Soteras, A.
Molecular and Cellular Neurobiology
Balkom, T. van
Anatomy and Neurosciences
Beker, N.
Neurology
Boedhoe, P.
Psychiatry
Boon, B.
Neurology
Classen, J.A. Coric, D. Dekker, I.
Functional Genomics Neurology Radiology
Dinga, R.
Psychiatry
Eijlers, A.J.C. Fathy, Y. Galle, S. Ganz, A
Anatomy and Neurosciences Anatomy and Neurosciences Clinical Neuropsychology Molecular and Cellular Neurobiology
Jansen, A,G,
Complex Trait Genetics
Joling, M.
Neurology
Kamermans, A.
Molecular Cell Biology
Karlsson Linner, R.
Complex Trait Genetics
Kiljan, S. Kloet, S.F. de
Anatomy and Neurosciences Integrative Neurophysiology
Koopman, T.
Nuclear Medicine
Kramer, G.
Legdeur, N.
Physics of Living Systems Biophotonics and Medical Imaging Ophthalmology Integrative Neurophysiology Neurology
Leijenaar, J.
Neurology
Kreeke, J.A. van Krugten, J. van
Project Multi-level brain criticality as a mechanism of complex variability in perception and learning Improving Neuron-ECM-Glia interactions in mental disorders Role of cognition on neuropsychiatry in Parkinson’s disease and the effect of cognitive rehabilitation Cognitive performance in centenarians Structure of the OCD brain (including ENIGMA) Pathological substrate of clinical variability in AD Project Classen Afferent neuro-ophthalmology in MS
Program VUmc NCA-BIT VUmc NCA-BMHD VUmc NCA-ND VUmc NCA-ND VUmc NCA-NMH VUmc NCA-ND VUmc NCA-BMHD VUmc NCA-NI VUmc NCA-NI
Machine learning applications in mood disorders'
VUmc NCA-NMH
Cognitive phenotypes in MS
VUmc NCA-ND
The role of the insula in cognitive symptoms in early Parkinson’s disease Physical activity and cognitive aging proteomics of 100-plus Study brain tissues Presynaptic gene networks for ADHD, anxiety disorders and other common psychiatric disorders in children and adolescents Extrastriatal FP-CIT binding in parkinsonism Unraveling the role of reactive glia in neurodegeneration Essays in genoeconomics and empirical research practices Histopathological correlates of network changes and cognition in MS
VUmc NCA-ND VUmc NCA-NMH VUmc NCA-ND VUmc NCA-BMHD VUmc NCA-ND VUmc NCA-NI VUmc NCA-NMH VUmc NCA-NI VUmc NCA-BIT
Multimodality and multi-parametric PET/MRI analysis for enhancing diagnosis, prognosis and response prediction in advanced stage head and neck cancer. IFT in C. elegans Polarization-sensitive Doppler Optical Coherence Tomography in Neurodegenerative Disease The link between single cell activity and cognitive performance Resilience to dementia at old age Symptomatic treatment of vascular cognitive impairments
12
VUmc NCA-BIT
VUmc NCA-BIT VUmc NCA-BIT VUmc NCA-BMHD VUmc NCA-ND VUmc NCA-ND
Annual Report 2015 - Appendices
Maurik, I. van
Neurology
Meddens, F.
Complex Trait Genetics
Nij Bijvank, J.A. Oort, Q.
Biophotonics and Medical Imaging Ophthalmology Neurology
Pike, A.F.
Clinical Chemistry
Rhodius-Meester, H.
Neurology
Moooij, B.
Risk estimates and algorithms to predict dementia in MCI Genoeconomics: Research at the Boundaries of Genetics and Economics
VUmc NCA-ND VUmc NCA-NMH
Extraterestial life
VUmc NCA-BIT
Afferent neuro-ophthalmology in MS
VUmc NCA-NI VUmc NCA-ND
Innate Immune Activation in Neurodegenerative Disease” Improvingclinical diagnosis in neurodegenerative diseases
VUmc NCA-ND VUmc NCA-ND
Sigurdsson, S.V. Steenoven, I. van
Biophotonics and Medical Imaging Clinical Genetics Neurology
Timmers, T
Neurology
Veij Mestdagh, C.
Molecular and Cellular Neurobiology
Vermunt, L.
Neurology
Alzheimer prevention studies, trial design and subject selection
VUmc NCA-ND
Vienola, K.
Biophotonics and Medical Imaging
Retinal imaging
VUmc NCA-BIT
Vijverberg, J.
Neurology
Neuropsychiatry of the frontal lobe syndrome
VUmc NCA-ND
Visser, M.
Physics and Medical Technology
PICTURE
VUmc NCA-BIT
Wesselman, L.
Neurology
Subjective cognitive decline in preclinical Alzheimer’s Disease: European initiative on a lifestyle-based prevention strategy
VUmc NCA-ND
Wiersma, V.I.
Functional Genomics
The UPR in the cell-to-cell spreading of tau pathology in dementia
Wit, N.M. de Zande, J. van der
Molecular Cell Biology Neurology
Sphingolipids in AD DLB: SPECT and EEG
Santen, J. van
Wavefront shaping
VUmc NCA-BIT
Biomarkers for Lewy Body dementia Tau imaging with [18F]T807 PET: the new frontier
VUmc NCA-BMHD VUmc NCA-ND VUmc NCA-ND, VUmc NCA-BIT VUmc NCA-ND
13
VUmc NCABMHD, VUmc NCA-ND VUmc NCA-NI VUmc NCA-ND
Annual Repprt 2015 - Appendices
Appendix 3: Scientific output Brain Imaging Technology Theses VU/VUmc PhD-student at VU (A) Diaz, B.A. (2015, November 10). The Amsterdam Resting-State Questionnaire. Measuring and characterizing resting-state cognition and its neural correlates. VU Vrije Universiteit (166 pag.) (Amsterdam: Gildeprint). Prom./coprom.: prof. dr. H.D. Mansvelder, Dr. K. Linkenkaer-Hansen & dr. E.J.W. van Someren. Folkersma, I.H. (2015, Maart 13). Activated Microglia After Traumatic Brain Injury. The Neuroinflammatory Mastermind. VU University. Prom./coprom.: prof. dr. W.P. Vandertop, prof. dr. A.A. Lammertsma, prof. dr. R. Boellaard & dr. B.N.M. van Berckel. Gerrits, N.J.H.M. (2015, September 11). Understanding cognitive heterogeneity in Parkinson's disease: An imaging approach. VU University. Prom./coprom.: prof. dr. D.J. Veltman, prof. dr. H.W. Berendse, dr. Y.D. van der Werf & dr. O.A. van den Heuvel. Kropholler, M.A. (2015, Mei 18). Quantification of (R)-[11C]PK11195 binding in man. VU University. Prom./coprom.: prof. dr. A.A. Lammertsma, prof. dr. R. Boellaard & dr. B.N.M. van Berckel. Ros, B.P. (2015, November 13). Stochastic modeling and statistical analysis of EEG-fMRI data. VU University. Prom./coprom.: prof. dr. M.C.M. de Gunst, dr. F. Bijma & dr. J.C. de Munck.
Scientific papers refereed Almasi, A., Brax, P., Iannuzzi, D. & Sedmik, R. (2015). Force sensor for chameleon and Casimir force experiments with parallel-plate configuration. Physical Review D, 91 (10), 102002. doi: 10.1103/PhysRevD.91.102002 Bakker, G., Vingerhoets, W.A., Wieringen, J.P. van, Bruin, K. de, Eersels, J.L.H., Jong, J. de, Chahid, Y., Rutten, B.P., DuBois, S., Watson, M., Mogg, A.J., Xiao, H., Crabtree, M., Collier, D. A., Felder, C.C., Barth, V.N., Broad, L.M., Bloemen, O.J., Amelsvoort, T.A. van & Booij, J. (2015). 123Iiododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo. Journal of Nuclear Medicine, 56 (2), 317-322. doi: 10.2967/jnumed.114.147488 Tewarie, P., Schoonheim, M.M., Schouten, D.I., Polman, C.H., Balk, L.J., Uitdehaag, B.M.J., Geurts, J.J.G., Hillebrand, A., Barkhof, F. & Stam, C.J. (2015). Functional Brain Networks: Linking Thalamic Atrophy to Clinical Disability in Multiple Sclerosis, A Multimodal fMRI and MEG Study. Human Brain Mapping, 36 (2), 603-618. doi: 10.1002/hbm.22650 Tewarie, P., Dellen, E. van, Hillebrand, A. & Stam, C.J. (2015). The minimum spanning tree: An unbiased method for brain network analysis. NeuroImage, 104, 177-188. doi: 10.1016/j.neuroimage.2014.10.015 Beekmans, S.V. & Iannuzzi, D. (2015). A metrological approach for the calibration of force transducers with interferometric readout. Surface Topography: Metrology and Properties, 3 (2). doi: 10.1088/2051-672X/3/2/025004 Biebricher, A.S., Heller, I., Roijmans, R.F.H., Hoekstra, T.P., Peterman, E.J.G. & Wuite, G.J.L. (2015). The impact of DNA intercalators on DNA and DNA-processing enzymes elucidated through forcedependent binding kinetics. Nature Communications, 6, 7304. doi: 10.1038/ncomms8304 Bijma, F. & Mc Assey, M.P. (2015). A clustering coefficient for complete weighted networks. Network Science. doi: 10.1017/nws.2014.26 Boellaard, R. & Quick, H.H. (2015). Current Image Acquisition Options in PET/MR. Seminars in Nuclear Medicine, 45 (3), 192-200. doi: 10.1053/j.semnuclmed.2014.12.001 Boellaard, R., Rausch, I., Beyer, T., Delso, G., Yaqub, M., Quick, H.H. & Sattler, B. (2015). Quality control for quantitative multicenter whole-body PET/MR studies: A NEMA image quality phantom study with three current PET/MR systems. Medical Physics, 42 (10), 5961-5969. doi: 10.1118/1.4930962
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Annual Report 2015 - Appendices
Bossong, M.G., Mehta, M.A., Berckel, B.N.M. van, Howes, O.D., Kahn, R. S. & Stokes, P.R.A. (2015). Further human evidence for striatal dopamine release induced by administration of a dagger 9tetrahydrocannabinol (THC): selectivity to limbic striatum. Psychopharmacology, 232 (15), 27232729. doi: 10.1007/s00213-015-3915-0 Bron, E.E., Smits, M., Flier, W.M. van der, Vrenken, H., Barkhof, F., Scheltens, P., Papma, J.M., Steketee, R.M.E., Orellana, C.M., Meijboom, R., Pinto, M., Meireles, J.R., Garrett, C., Bastos-Leite, A.J., Abdulkadir, A., Ronneberger, O., Amoroso, N., Bellotti, R., Cardenas-Pena, D., Alvarez-Meza, A.M., Dolph, C.V., Iftekharuddin, K.M., Eskildsen, S.F., Coupe, P., Fonov, V.S., Franke, K., Gaser, C., Ledig, C., Guerrero, R., Tong, T., Gray, K.R., Moradi, E., Tohka, J., Routier, A., Durrleman, S., Sarica, A., Fatta, G. Di, Sensi, F., Chincarini, A., Smith, G.M., Stoyanov, Z.V., Sorensen, L., Nielsen, M., Tangaro, S., Inglese, P., Wachinger, C., Reuter, M., Swieten, J.C. van, Niessen, W.J. & Klein, S. (2015). Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge. NeuroImage, 111, 562-579. doi: 10.1016/j.neuroimage.2015.01.048 Brouwer, I., Giniatullina, A., Laurens, N., Weering, J.R.T. van, Bald, D., Wuite, G.J.L. & Groffen, A.J.A. (2015). Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes. Nature Communications, 6, 8387. doi: 10.1038/ncomms9387 Brouwer, R.M., Koenis, M.M.G., Schnack, H.G., Baal, G.C.M. van, Soelen, I.L.C. van, Boomsma, D.I. & Hulshoff Pol, H.E. (2015). Longitudinal Development of Hormone Levels and Grey Matter Density in 9 and 12-Year-Old Twins. Behavior Genetics, 45 (3), 313-323. doi: 10.1007/s10519-015-9708-8 Cabanas Danes, J., Hoekstra, T.P., Heller, I., Peterman, E.J.G. & Wuite, G.J.L. (2015). Unraveling the Interplay between Single-Stranded DNA-Binding Protein, DNA Polymerase and Single-Stranded DNA. Biophysical Journal, 108 (2), 67A-67A. Candelli, A., Brouwer, I., Sitters, G., Heerema, S., Modesti, M., Peterman, E.J.G. & Wuite, G.J.L. (2015). DNA Translocations in Real-Time: Insights into Non-Homologous End Joining Pathway. Biophysical Journal, 108 (2), 507A-507A. Cheng, J.C., Boellaard, R. & Laforest, R. (2015). Evaluation of the Effect of Magnetic Field on PET Spatial Resolution and Contrast Recovery Using Clinical PET Scanners and EGSnrc Simulations. IEEE Transactions on Nuclear Science, 62 (1), 101-110. doi: 10.1109/TNS.2014.2373147 Diessen, E. van, Numan, T., Dellen, E. van, Kooi, A.W. van der, Boersma, M., Hofman, D., Lutterveld, R. van, Dijk, B.W. van, Straaten, E.C.W. van, Hillebrand, A. & Stam, C.J. (2015). Opportunities and methodological challenges in EEG and MEG resting state functional brain network research. Clinical Neurophysiology, 126 (8), 1468-1481. doi: 10.1016/j.clinph.2014.11.018 Donato, M. di & Groot, M.L. (2015). Ultrafast infrared spectroscopy in photosynthesis. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1847 (1), 2-11. doi: 10.1016/j.bbabio.2014.06.006 Dyrba, M., Barkhof, F., Fellgiebel, A., Filippi, M., Hausner, L., Hauenstein, K., Kirste, T. & Teipel, S.J (2015). Predicting Prodromal Alzheimer's Disease in Subjects with Mild Cognitive Impairment Using Machine Learning Classification of Multimodal Multicenter Diffusion-Tensor and Magnetic Resonance Imaging Data. Journal of Neuroimaging, 25 (5), 738-747. doi: 10.1111/jon.12214 Enzinger, C., Barkhof, F., Ciccarelli, O., Filippi, M., Kappos, L., Rocca, M.A., Ropele, S., Rovira, A., Schneider, T., Stefano, N. De, Vrenken, H., Wheeler-Kingshott, C., Wuerfel, J. & Fazekas, F. (2015). Nonconventional MRI and microstructural cerebral changes in multiple sclerosis. Nature Reviews Neurology, 11 (12), 676-686. doi: 10.1038/nrneurol.2015.194 Fraschini, M., Hillebrand, A., Demuru, M., Didaci, L. & Marcialis, G.L. (2015). An EEG-Based Biometric System Using Eigenvector Centrality in Resting State Brain Networks. Ieee signal processing letters, 22 (6), 666-670. doi: 10.1109/LSP.2014.2367091 Frisoni, G. B., Jack, C.R., Bocchetta, M., Bauer, C., Frederiksen, K.S., Liu, Y.W., Preboske, G., Swihart, T., Blair, M., Cavedo, E., Grothe, M.J., Lanfredi, M., Martinez, O., Nishikawa, M., Portegies, M., Stoub, T., Ward, C., Apostolova, L.G., Ganzola, R., Wolf, D., Barkhof, F., Bartzokis, G., deCarli, C., Csernansky, J.G., DeToledo-Morrell, L., Geerlings, M.I., Kaye, J., Killiany, R.J., Lehericy, S., Matsuda, H., O'Brien, J., Silbert, L.C., Scheltens, P., Soininen, H., Teipel, S., Waldemar, G., Fellgiebel, A., Barnes, J., Firbank, M., Gerritsen, L., Henneman, W., Malykhin, N., Pruessner, J.C., Wang, L., Watson, C., Wolf, H, deLeon, M., Pantel, J., Ferrari, C., Bosco, P., Pasqualetti, P., Duchesne, S., Duvernoy, H. & Boccardi, M. (2015). The EADC-ADNI Harmonized Protocol for manual hippocampal
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segmentation on magnetic resonance: Evidence of validity. Alzheimers & Dementia, 11 (2), 111125. doi: 10.1016/j.jalz.2014.05.1756 Froklage, E.A.M., Boellaard, R., Bakker, E.N., Hendrikse, N.H., Reijneveld, J.C., Schuit, R.C., Windhorst, A.D., Schober, P., Berckel, B.N.M. van, Lammertsma, A.A. & Postnov, A. (2015). Quantification of C11-Laniquidar Kinetics in the Brain. Journal of Nuclear Medicine, 56 (11), 1730-1735. doi: 10.2967/jnumed.115.157586 Gass, A., Rocca, M.A., Agosta, F., Ciccarelli, O., Chard, D., Valsasina, P., Brooks, J.C.W., Bischof, A., Eisele, P., Kappos, L., Barkhof, F., Filippi, M. & Vrenken, H. (2015). MRI monitoring of pathological changes in the spinal cord in patients with multiple sclerosis. Lancet Neurology, 14 (4), 443-454. doi: 10.1016/S1474-4422(14)70294-7 Gee, A.D. & Windhorst, A.D. (2015). Bengt Langstrom-a pioneer in carbon-11 radiochemistry. Journal of Labelled Compounds and Radiopharmaceuticals, 58 (3), 47-48. doi: 10.1002/jlcr.3278 Golla, S.V.V., Klein, P.J., Bakker, J., Schuit, R.C., Christiaans, J.A.M., Geest, L. van der, Kooijman, E.J.M., Oropeza-Seguias, G.M., Langermans, J.A.M., Leysen, J.E., Boellaard, R., Windhorst, A.D., Berckel, B.N.M. van & Metaxas, A. (2015). Preclinical evaluation of [F-18]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors. Nuclear Medicine and Biology, 42 (2), 205-212. doi: 10.1016/j.nucmedbio.2014.09.006 Golla, S.V.V., Boellaard, R., Oikonen, V., Hoffmann, A., Berckel, B.N.M. van, Windhorst, A.D., Virta, J., Haaparanta-Solin, M., Luoto, P., Savisto, N., Solin, O., Valencia, R., Thiele, A., Eriksson, J., Schuit, R.C., Lammertsma, A.A. & Rinne, J.O. (2015). Quantification of [F-18]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients. Journal of Cerebral Blood Flow and Metabolism, 35 (5), 766-772. doi: 10.1038/jcbfm.2014.261 Hacker, M., Beyer, T., Baum, R.P., Kalemis, A., Lammertsma, A.A., Lewington, V., Talbot, J.N. & Verzijlbergen, F. (2015). Nuclear medicine innovations help (drive) healthcare (benefits). European Journal of Nuclear Medicine and Molecular Imaging, 42 (2), 173-175. doi: 10.1007/s00259-0142957-6 Hermans, K, Ossenblok, P., Houdt, P.J. van, Geerts, L., Verdaasdonk, R.M., Boon, P., Colon, A. & Munck, J.C. de (2015). Network analysis of EEG related functional MRI changes due to medication withdrawal in focal epilepsy. 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Jr., Kochunov, P., Kwok, J.B., Lawrie, S.M., Liu, X., Longo, D.L., McMahon, K.L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G.W., Mostert, J.C., Mühleisen, T.W., Nalls, M.A., Nichols, T.E., Nilsson, L.G., Nöthen, M.M., Ohi, K., Olvera, R.L., Perez-Iglesias, R., Pike, G.B., Potkin, S.G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G.D., Rujescu, D., Schnell, K., Schofield, P.R., Smith, C., Steen, V.M., Sussmann, J.E., Thalamuthu, A., Toga, A.W., Traynor, B.J., Troncoso, J., Turner, J.A., Valdés Hernández, M.C., Ent, D. van t, Brug, M. van der, Wee, N.J.A. van der, Tol, M.J. van, Veltman, D.J., Wassink, T.H., Westmann, E., Zielke, R.H.,
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Zonderman, A.B., Ashbrook, D.G., Hager, R., Lu, L., McMahon, F.J., Morris, D.W., Williams, R.W., Brunner, H.G., Buckner, R.L., Buitelaar, J.K., Cahn, W., Calhoun, V.D., Cavalleri, G.L., CrespoFacorro, B., Dale, A.M., Davies, G.E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W.C., Espeseth, T., Gollub, R.L., Ho, B.C., Hoffmann, W., Hosten, N., Kahn, R.S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B.W.J.H., Roffman, J.L., Sisodiya, SM, Smoller, J.W., Bokhoven, H. van, Haren, N.E.M. van, Völzke, H., Walter, H., Weiner, M.W., Wen, W., White, T., Agartz, I., Andreassen, O.A., Blangero, J., Boomsma, D.I., Brouwer, R.M., Cannon, D.M., Cookson, M.R., Geus, E.J.C. de, Deary, I.J., Donohoe, G., Fernandez, G., Fisher, S.E., Francks, C., Glahn, D.C., Grabe, H.J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H.E., Jönsson, E.G., Kloszewska, I., Lovestone, S., Mattay, V.S., Mecocci, P., McDonald, C., McIntosh, A.M., Ophoff, R.A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P.S., Saykin, A.J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J.M., Weale, M.E., Weinberger, D.R., Adams, H.H.H., Launer, L.J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C.L., Becker, J.T., Yanek, L., Lee, S.J. van der, Ebling, M., Fischl, B., Longstreth, Jr. W.T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L.N., Duijn, C.M. van, Xue, L., Mazoyer, B., Bis, J.C., Gudnason, V., Seshadri, S., Arfan Ikram, M., Martin, N.G., Wright, M.J., Schumann, G., Franke, B., Thompson, P.M. & Medland, S.E. (2015). Common genetic variants influence human subcortical brain structures. Nature, 520 (7546), 224-229. doi: 10.1038/nature14101 Hinz, R. & Boellaard, R. (2015). Challenges of quantification of TSPO in the human brain. Clinical and Translational Imaging, 3 (6), 403-416. doi: 10.1007/s40336-015-0138-7 Hoekzema, E., Schagen, S.E.E., Kreukels, B.P.C., Veltman, D.J., Cohen-Kettenis, P.T., Waal, H.A. Delemarrevan d & Bakkera, J. (2015). Regional volumes and spatial volumetric distribution of gray matter in the gender dysphoric brain. Psychoneuroendocrinology, 55, 59-71. doi: 10.1016/j.psyneuen.2015.01.016 Hoorn, C.H. van, Ariese, F., Iannuzzi, D. & Mank, A.J.G. (2015). Using ferrule-top opto-mechanical probes as a new tool in VCSEL reliability experiments. Optics Express, 23 (23), 30318-30328. doi: 10.1364/OE.23.030318 Houdt, P.J. van, Ossenblok, P.P.W., Colon, A.J., Hermans, K.H.M., Verdaasdonk, R.M., Boon, P.A.J.M. & Munck, J.C. de (2015). Are Epilepsy-Related fMRI Components Dependent on the Presence of Interictal Epileptic Discharges in Scalp EEG? Brain Topography, 28 (4), 606-618. doi: 10.1007/s10548-014-0407-1 Jain, S., Sima, D.M., Ribbens, A., Cambron, M., Maertens, A., Van Hecke, W., De Meij, J., Barkhof, F., Steenwijk, M.D., Daams, M., Maes, F., Van Huffel, S., Vrenken, H. & Smeets, D. (2015). Automatic segmentation and volumetry of multiple sclerosis brain lesions from MR images. NeuroImage: Clinical, 8, 367-375. doi: 10.1016/j.nicl.2015.05.003 Kamsma, D., Sitters, G., Thalhammer, G., Ritsch-Marte, M., Peterman, E.J.G. & Wuite, G.J.L. (2015). Acoustic Force Spectroscopy. Biophysical Journal, 108 (2), 355A-355A. King, G.A., Peterman, E.J.G. & Wuite, G.J.L. (2015). Tension-Dependent Stability of Torsionally Constrained DNA: Melting Precedes Overwinding. Biophysical Journal, 108 (2), 233A-233A. Klein, P.J., Christiaans, J.A.M., Metaxas, A., Schuit, R.C., Lammertsma, A.A., Berckel, B.N.M. van & Windhorst, A.D. (2015). Synthesis, structure activity relationship, radiolabeling and preclinical evaluation of high affinity ligands for the ion channel of the N-methyl-D-aspartate receptor as potential imaging probes for positron emission tomography. Bioorganic and Medicinal Chemistry, 23 (5), 1189-1206. doi: 10.1016/j.bmc.2014.12.029 Kloet, S.F. de, Mansvelder, H.D. & Vries, T.J. de (2015). Cholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors. Biochemical Pharmacology, 97 (4), 425-438. doi: 10.1016/j.bcp.2015.07.014 Klooster, M.A. Van't, Leijten, F.S.S., Huiskamp, G., Ronner, H.E., Baayen, J.C., Rijen, P.C. van, Eijkemans, M.J.C., Braun, K.P.J. & Zijlmans, M. (2015). High frequency oscillations in the intra-operative ECoG to guide epilepsy surgery ("The HFO Trial"): study protocol for a randomized controlled trial. Trials, 16, 422. doi: 10.1186/s13063-015-0932-6 Kloosterman, N.A., Meindertsma, T., Hillebrand, A., Dijk, B.W. van, Lamme, V.A.F. & Donner, T.H. (2015). Top-down modulation in human visual cortex predicts the stability of a perceptual illusion. Journal of Neurophysiology, 113 (4), 1063-1076. doi: 10.1152/jn.00338.2014
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Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T.E., Wright, S.N., Hong, L.E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S.N., Brouwer, R.M., Landman, B., Lemaitre, H., Braber, A. den, Zwiers, M.P., Ritchie, S., Hulzen, K.J.E. van, Almasy, L., Curran, J., Zubicaray, G.I. de, Duggirala, R., Fox, P., Martin, N.G., McMahon, K.L., Mitchell, B., Olvera, R.L., Peterson, C., Starr, J., Sussmann, J.E., Wardlaw, J.M., Wright, M., Boomsma, D.I., Kahn, R.S., Geus, E.J.C. de, Williamson, D.E., Hariri, A., Ent, D. van t, Bastin, M.E., McIntosh, A., Deary, I.J., Hulshoff Pol, H.E., Blangero, J., Thompson, P.M., Glahn, D.C. & Essen, D.C. van (2015). Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data. NeuroImage, 111, 300-311. doi: 10.1016/j.neuroimage.2015.02.050 Koenis, M.M.G., Brouwer, R.M., Heuvel, M.P., Mandl, R.C.W., Soelen, I.L.C. van, Kahn, R.S., Boomsma, D.I. & Hulshoff Pol, H.E. (2015). Development of the Brain’s Structural Network Efficiency in Early Adolescence: A Longitudinal DTI Twin Study. Human Brain Mapping, 36 (12), 4938-4953. doi: 10.1002/hbm.22988 Kolff-Gart, A.S., Pouwels, P.J.W., Noij, D.P., Ljumanovic, R., Vandecaveye, V., Keyzer, F. de, Bree, R. de, Graaf, P. de, Knol, D.L. & Castelijns, J.A. (2015). Diffusion-Weighted Imaging of the Head and Neck in Healthy Subjects: Reproducibility of ADC Values in Different MRI Systems and Repeat Sessions. American Journal of Neuroradiology, 36 (2), 384-390. doi: 10.3174/ajnr.A4114 Lin, S., Cabanas Danes, J., Hoekstra, T.P., Kamsma, D., Sitters, G., Depken, S.M., Dame, R.T. & Wuite, G.J.L. (2015). Resolving the Kinetic States of a Proofreading DNA Polymerase. Biophysical Journal, 108 (2), 70A-70A. Liu, Y., Fu, Y., Schoonheim, M.M., Zhang, N., Fan, M.L., Su, L., Shen, Y., Yan, Y.P., Yang, L., Wang, Q.H., Zhang, N.N.N., Yu, C.S., Barkhof, F. & Shi, F.D. (2015). Structural MRI substrates of cognitive impairment in neuromyelitis optica. Neurology, 85 (17), 1491-1499. doi: 10.1212/WNL.0000000000002067 Liu, Y.O., Duan, Y.Y., Huang, J., Ren, Z.Q., Ye, J., Dong, H.Q., Shi, F.D., Barkhof, F., Vrenken, H., Wattjes, M.P., Wang, J.H. & Li, K.C. (2015). Multimodal Quantitative MR Imaging of the Thalamus in Multiple Sclerosis and Neuromyelitis Optica. Radiology, 277 (3), 784-792. doi: 10.1148/radiol.2015142786 Mansor, S., Boellaard, R., Froklage, F.E., Bakker, E.D.M., Yaqub, M., Voskuyl, R.A., Schwarte, L.A., Verbeek, J., Windhorst, A.D. & Lammertsma, A.A. (2015). Quantification of Dynamic C-11-Phenytoin PET Studies. Journal of Nuclear Medicine, 56 (9), 1372-1377. doi: 10.2967/jnumed.115.158055 Marizzoni, M., Antelmi, L., Bosch, B., Bartres-Faz, D., Muller, B.W., Wiltfang, J., Fiedler, U., Roccatagliata, L., Picco, A., Nobili, F., Blin, O., Bombois, S., Lopes, R., Sein, J., Ranjeva, J.P., Didic, M., Gros-Dagnac, H., Payoux, P., Zoccatelli, G., Alessandrini, F., Beltramello, A., Bargallo, N., Ferretti, A., Caulo, M., Aiello, M., Cavaliere, C., Soricelli, A., Salvadori, N., Parnetti, L., Tarducci, R., Floridi, P., Tsolaki, M., Constantinidis, M., Drevelegas, A., Rossini, P.M., Marra, C., Hoffmann, K.T., Hensch, T., Schonknecht, P., Kuijer, J.P., Visser, P.J., Barkhof, F., Bordet, R., Frisoni, G. B. & Jovicich, J. (2015). Longitudinal reproducibility of automatically segmented hippocampal subfields: A multisite European 3T study on healthy elderly. Human Brain Mapping, 36 (9), 3516-3527. doi: 10.1002/hbm.22859 Menning, S., Ruiter, M.B. de, Veltman, D.J., Koppelmans, V., Kirschbaum, C., Boogerd, W., Reneman, L. & Schagen, S.B. (2015). Multimodal MRI and cognitive function in patients with breast cancer prior to adjuvant treatment--the role of fatigue. NeuroImage: Clinical, 7, 547-554. doi: 10.1016/j.nicl.2015.02.005 Mijalkovic, J., Prevo, B., Oswald, F., Mangeol, P.J.J. & Peterman, E.J.G. (2015). Quantification of IFT-Dynein Dynamics in C. elegans. Biophysical Journal, 108 (2), 134A-134A. Morbelli, S., Garibotto, V., Giessen, E. van der, Arbizu, J., Chetelat, G., Drezgza, A., Hesse, S., Lammertsma, A.A., Law, I., Pappata, S., Payoux, P. & Pagani, M. (2015). A Cochrane review on brain [F-18]FDG PET in dementia: limitations and future perspectives. European Journal of Nuclear Medicine and Molecular Imaging, 42 (10), 1487-1491. doi: 10.1007/s00259-015-3098-2 Mutsaerts, H.J.M.M., Steketee, R.M.E., Heijtel, D.F.R., Kuijer, J.P.A., Osch, M.J.P. van, Majoie, C.B.L.M., Smits, M. & Nederveen, A.J. (2015). Reproducibility of pharmacological ASL using sequences from
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different vendors: implications for multicenter drug studies. Magnetic resonance materials in physics biology and medicine, 28 (5), 427-436. doi: 10.1007/s10334-014-0480-1 Onuki, Y., Someren, E.J.W. van, Zeeuw, C.I. & Werf, Y.D. van der (2015). Hippocampal–Cerebellar Interaction During Spatio-Temporal Prediction. Cerebral Cortex, 25 (2), 313-321. doi: 10.1093/cercor/bht221 Otte, W.M., Diessen, E. van, Paul, S., Ramaswamy, R., Rallabandi, V.P.S., Stam, C.J. & Roy, P.K. (2015). Aging alterations in whole-brain networks during adulthood mapped with the minimum spanning tree indices: The interplay of density, connectivity cost and life-time trajectory. NeuroImage, 109, 171-189. doi: 10.1016/j.neuroimage.2015.01.011 Pekosak, A., Filp, U.R., Rotteveel, L., Poot, A.J. & Windhorst, A.D. (2015). Improved synthesis and application of [C-11]benzyl iodide in positron emission tomography radiotracer production. Journal of Labelled Compounds and Radiopharmaceuticals, 58 (8), 342-348. doi: 10.1002/jlcr.3307 Piantoni, G., Werf, Y.D. van der, Jensen, O. & Someren, E.J.W. van (2015). Memory Traces of Long-Range Coordinated Oscillations in the Sleeping Human Brain. Human Brain Mapping, 36 (1), 67-84. doi: 10.1002/hbm.22613 Prevo, B. & Peterman, E.J.G. (2015). Small steps and giant leaps. eLife, 4, e08366. doi: 10.7554/eLife.08366 Raaphorst, R.M., Windhorst, A.D., Elsinga, P.H., Colabufo, N.A., Lammertsma, A.A. & Luurtsema, G (2015). Radiopharmaceuticals for Assessing ABC Transporters at the Blood-Brain Barrier. Clinical Pharmacology & Therapeutics, 97 (4), 362-371. doi: 10.1002/cpt.73 Radue, E.W., Barkhof, F., Kappos, L., Sprenger, T., Haring, D.A., Vera, A. de, Rosenstiel, P. von, Bright, J.R., Francis, G. & Cohen, J.A. (2015). Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. Neurology, 84 (8), 784-793. doi: 10.1212/WNL.0000000000001281 Redolfi, A., Manset, D., Barkhof, F., Wahlund, L.O., Glatard, T., Mangin, J.F. & Frisoni, G. B. (2015). Headto-Head Comparison of Two Popular Cortical Thickness Extraction Algorithms: A Cross-Sectional and Longitudinal Study. PLoS One, 10 (3):e0117692. doi: 10.1371/journal.pone.0117692 Ros, B.P., Bijma, F., Gunst, M.C.M. de & Munck, J.C. de (2015). A three domain covariance framework for EEG/MEG data. NeuroImage, 119, 305-315. doi: 10.1016/j.neuroimage.2015.06.020 Rosmalen, M.G.M. van, Biebricher, A.S., Kamsma, D., Zlotnick, A., Wuite, G.J.L. & Roos, W.H. (2015). DNAInduced Viral Assembly Studied in Real-Time by Optical Tweezers, Acoustic Force Spectroscopy and Atomic Force Microscopy. Biophysical Journal, 108 (2), 170A-170A. Rosmalen, M.G.M. van, Roos, W.H. & Wuite, G.J.L. (2015). Material properties of viral nanocages explored by atomic force microscopy. Methods in Molecular Biology, 1252, 115-137. doi: 10.1007/978-14939-2131-7_11 Rovira, A., Wattjes, M.P., Tintore, M., Tur, C., Yousry, T.A., Sormani, M.P., Stefano, N. De, Filippi, M., Auger, C., Rocca, M.A., Barkhof, F., Fazekas, F., Kappos, L., Polman, C., Miller, D. & Montalban, X. (2015). MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-clinical implementation in the diagnostic process. Nature Reviews Neurology, 11 (8), 471-482. doi: 10.1038/nrneurol.2015.106 Savolainen, H., Cantore, M., Colabufo, N.A., Elsinga, P.H., Windhorst, A.D. & Luurtsema, G (2015). Synthesis and Preclinical Evaluation of Three Novel Fluorine-18 Labeled Radiopharmaceuticals for P-Glycoprotein PET Imaging at the Blood-Brain Barrier. Molecular Pharmaceutics, 12 (7), 22652275. doi: 10.1021/mp5008103 Schmid, S., Heijtel, D.F.R., Mutsaerts, H.J.M.M., Boellaard, R., Lammertsma, A.A., Nederveen, A.J. & Osch, M.J.P. van (2015). Comparison of velocity- and acceleration-selective arterial spin labeling with [O15]H2O positron emission tomography. Journal of Cerebral Blood Flow and Metabolism, 35 (8), 1296-1303. doi: 10.1038/jcbfm.2015.42 Schnack, H.G., Haren, N.E.M. van, Brouwer, R.M., Evans, A., Durston, S., Boomsma, D.I., Kahn, R.S. & Hulshoff Pol, H.E. (2015). Changes in Thickness and Surface Area of the Human Cortex and Their Relationship with Intelligence. Cerebral Cortex, 25 (6), 1608-1617. doi: 10.1093/cercor/bht357 Sitters, G., Kamsma, D., Thalhammer, G., Ritsch-Marte, M., Peterman, E.J.G. & Wuite, G.J.L. (2015). Acoustic force spectroscopy. Nature Methods, 12 (1), 47-50. Staphorsius, A.S., Kreukels, B.P.C., Cohen-Kettenis, P.T., Veltman, D.J., Burke, S.M., Schagen, S.E.E., Wouters, F.M., Waal, H.A. Delemarre-van d & Bakker, J. (2015). Puberty suppression and executive
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functioning: An fMRI-study in adolescents with gender dysphoria. Psychoneuroendocrinology, 56, 190-199. doi: 10.1016/j.psyneuen.2015.03.007 Stoffers, D., Diaz, B.A., Cheng, G., Braber, A. den, Ent, D. van t, Boomsma, D.I., Mansvelder, H.D., Geus, E.J.C. de, Someren, E.J.W. van & Linkenkaer-Hansen, K. (2015). Resting-State fMRI Functional Connectivity Is Associated with Sleepiness, Imagery, and Discontinuity of Mind. PLoS One, 10 (11):e0142014. doi: 10.1371/journal.pone.0142014 Tolboom, N., Berendse, H.W., Leysen, J.E., Yaqub, M., Berckel, B.N.M. van, Schuit, R.C., Ponsen, M.M., Bakker, E., Hoetjes, N.J., Windhorst, A.D., Carlsson, M.L., Lammertsma, A.A. & Carlsson, A. (2015). The Dopamine Stabilizer (-)-OSU6162 Occupies a Subpopulation of Striatal Dopamine D2/D3 Receptors: An [C-11] Raclopride PET Study in Healthy Human Subjects. Neuropsychopharmacology, 40 (2), 472-479. doi: 10.1038/npp.2014.195 Varadarajan, A., Oswald, F., Bollen, Y.J.M. & Peterman, E.J.G. (2015). Membrane-Protein Diffusion in E. coli: A Random Walk in a Heterogeneous Landscape. Biophysical Journal, 108 (2), 323A-323A. Varrone, A. & Lammertsma, A.A. (2015). Imaging of neuroinflammation: TSPO and beyond. Clinical and Translational Imaging, 3 (6), 389-390. doi: 10.1007/s40336-015-0149-4 Velden, F.H.P. van, Mansor, M.S.B., Assema, D.M.E. van, Berckel, B.N.M. van, Froklage, F.E., Wang, S.N., Schuit, R.C., Asselin, M.C., Lammertsma, A.A., Boellaard, R. & Huisman, M.C. (2015). Comparison of HRRT and HR plus Scanners for Quantitative (R)-[C-11]verapamil, [C-11]raclopride and [C11]flumazenil Brain Studies. Molecular Imaging and Biology, 17 (1), 129-139. doi: 10.1007/s11307014-0766-8 Ven, R.M. van de, Schmand, B., Groet, E., Veltman, D.J. & Murre, J.M.J. (2015). The effect of computerbased cognitive flexibility training on recovery of executive function after stroke: rationale, design and methods of the TAPASS study. BMC Neurology, 15, 144. doi: 10.1186/s12883-015-0397-y Waelbers, T., Polis, I., Vermeire, S., Dobbeleir, A., Eersels, J.L.H., Spiegeleer, B. De, Audenaert, K. & Peremans, K. (2015). Effect of ketamine on the regional cerebral blood flow and binding index of the 5-HT2A receptor radioligand I-123-R91150 in the canine brain. Journal of veterinary behaviorclinical applications and research, 10 (4), 332-337. doi: 10.1016/j.jveb.2015.03.009 Wattjes, M.P., Rovira, A., Miller, D., Yousry, T.A., Sormani, M.P., Stefano, N. De, Tintore, M., Auger, C., Tur, C., Filippi, M., Rocca, M.A., Fazekas, F., Kappos, L., Polman, C., Barkhof, F. & Montalban, X. (2015). Evidence-Based Guidelines Magnims Consensus Guidelines on the Use of Mri in Multiple Sclerosis-Establishing Disease Prognosis and Monitoring Patients. Nature Reviews Neurology, 11 (10), 597-606. doi: 10.1038/nrneurol.2015.157 Wattjes, M.P., Vennegoor, A., Steenwijk, M.D., Vos, M., Killestein, J., Oosten, B.W. van, Mostert, J., Siepman, D.A., Moll, W., Golde, A.E.L. van, Frequin, S.T.F.M., Richert, N.D. & Barkhof, F. (2015). MRI pattern in asymptomatic natalizumab-associated PML. Journal of Neurology, Neurosurgery and Psychiatry, 86 (7), 793-798. doi: 10.1136/jnnp-2014-308630 Willemse, R.B., Hillebrand, A., Ronner, H.E., Vandertop, W.P. & Stam, C.J. (2015). Magnetoencephalographic study of hand and foot sensorimotor organization in 325 consecutive patients evaluated for tumor or epilepsy surgery. NeuroImage: Clinical, 10, 46-53. doi: 10.1016/j.nicl.2015.11.002 Winfield, J.M., Papoutsaki, M.V., Ragheb, H., Morris, D.M., Heerschap, A., Voert, E.G.W. ter, Kuijer, J.P.A., Pieters, I.C., Douglas, N.H.M., Orton, M. & Souza, N.M. de (2015). Development of a diffusionweighted MRI protocol for multicentre abdominal imaging and evaluation of the effects of fasting on measurement of apparent diffusion coefficients (ADCs) in healthy liver. British Journal of Radiology, 88 (1049), 20140717. doi: 10.1259/bjr.20140717 Wuite, G.J.L. & Peterman, E.J.G. (2015). Grab & Watch: Correlative Optical Tweezers-Fluorescence Microscopy (CTFM) as a Versatile Tool for Biological Studies. Biophysical Journal, 108 (2), 166A166A. Xekardaki, A., Rodriguez, C., Montandon, M.L., Toma, S., Tombeur, E., Herrmann, F.R., Zekry, D., Lovblad, K.O., Barkhof, F., Giannakopoulos, P. & Haller, S. (2015). Arterial Spin Labeling May Contribute to the Prediction of Cognitive Deterioration in Healthy Elderly Individuals. Radiology, 274 (2), 490499. doi: 10.1148/radiol.14140680 Yu, M.C., Hillebrand, A., Tewarie, P., Meier, J., Dijk, B. van, Mieghem, P. Van & Stam, C.J. (2015). Hierarchical clustering in minimum spanning trees. Chaos, 25 (2), 023107. doi: 10.1063/1.4908014
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Zhang, L.J., Zhao, N., Fu, Y., Zhang, D.Q., Wang, J., Qin, W., Zhang, N.N.N., Wood, K., Liu, Y., Yu, C.S., Shi, F.D. & Yang, L. (2015). Olfactory dysfunction in neuromyelitis optica spectrum disorders. Journal of Neurology, 262 (8), 1890-1898. doi: 10.1007/s00415-015-7787-3
Scientific papers non-refereed Numan, T., Stam, C.J., Slooter, A.J.C. & Dellen, E. van (2015). Being Conscious of Methodological Pitfalls in Functional Brain Network Analysis. Anesthesiology, 123 (2), 484-485. doi: 10.1097/ALN.0000000000000750
Scientific publications (books, monographs, book chapters, proceedings) Berckel, B.N.M. van, Lammertsma, A.A. & Boellaard, R. (2015). Positron emission tomography. In M. Filippi (Ed.), Oxford Textbooks in Clinical Neurology (Oxford Textbooks in Clinical Neurology, 9) (pp. 90-96). Oxford: Oxford University Press. Iannuzzi, D. & Sedmik, R. (2015). Van der Waals and Casimir forces. In G. Chiarotti & P., Chiaradia (Eds.), Physics of Solid Surfaces: Subvolume A. Chapter 13 (pp. 692-750. Springer.
Professional publications Kamer, J. Van de & Lammertsma, A.A. (2015). Stralingsrisico moet anders beoordeeld. Medisch Contact, 22, 1095-1095.
Brain Mechanisms in Health & Disease Theses VU/VUmc PhD-student at VU (A) Astill-Schutte, R.G. (2015, April 22). Don't let the bedbugs bite: Sleep's beneficial effects on childhood cognitive development. VU University. Prom./coprom.: prof. dr. E.J.W. Someren & dr. Y.D. van der Werf. Boudewijns, Z.S.R.M. (2015, April 21). Integrative properties of cortical pyramidal neurons--Linking structure to function. VU Vrije Universiteit (160 pag.). Prom./coprom.: prof. dr. H.D. Mansvelder & Dr. C.P.J. de Kock. Bugiani, M. (2015, Juni 30). Comparing and contrasting white matter disorders: a neuropathological approach to pathophysiology. VU University. Prom./coprom.: prof. dr. M.S. van der Knaap & prof. dr. P. van der Valk. Dawitz, J. (2015, September 29). From Neurodevelopment to Neurodevelopmental Disorders: Glutamatergic Networks in Health and Disease. VU Vrije Universiteit (195 pag.). Prom./coprom.: prof. dr. H.D. Mansvelder & dr. R.M. Meredith. Geytenbeek, J.J.M. (2015, April 01). Comprehension of spoken language in non-speaking children with severe cerebral palsy: Development and application of a newly developed Computer-Based instrument for low motor language testing (C-BiLLT). VU University. Prom./coprom.: prof.dr. J.G. Becher, prof. dr. M.S. van der Knaap, dr. R.J. Vermeulen & dr. K.J. Oostrom. Giniatullina, A. (2015, September 23). C2 domain function in healthy and diseases brain. VU Vrije Universiteit. Prom./coprom.: prof. dr. M. Verhage & dr. ir. A.J.A. Groffen. Goudriaan, A. (2015, December 16). Glial Genetics in Central Nervous System Connectivity and Psychiatric Diseases. VU Vrije Universiteit. Prom./coprom.: prof. dr. A.B. Smit & dr. M.H.G. Verheijen. Hager, T. (2015, September 29). Advanced autonomic and behavioral phenotyping of emotional behavior of mice. VU University. Prom./coprom.: prof. dr. M. Verhage & Dr. O. Stiedl. Kerkoerle, T.J. van (2015, December 03). Feedforward and Feedback Processing in Monkey Visual Cortex. VU University. Prom./coprom.: prof. dr. P.R. Roelfsema.
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Kurps, J. (2015, September 29). Organizing Sites for Regulated Secretion in Adrenal Chromaffin Cells. VU University. Prom./coprom.: prof. dr. M. Verhage & J.R.T. van Weering. Lei, H.D.W. van der (2015, December 01). Vanishing white matter: A study of phenotypic variation and the relationship between genotype and phenotype. VU University. Prom./coprom.: prof. dr. M.S. van der Knaap, dr. ir. G.C. Scheper & G.E.M. Abbink. Steenweg, M.E. (2015, April 04). Childhood white matter disorders: Research at the interface of MRI, clinical phenotype and genetics. VU University. Prom./coprom.: prof. dr. M.S. van der Knaap, prof. dr. F. Barkhof & dr. P.J.W. Pouwels. Stroeder, J. (2015, Juni 18). Shisa proteins and AMPA-receptor fuction. VU Vrije Universiteit (148 pag.). Prom./coprom.: prof. dr. H.D. Mansvelder & prof. dr. A.B. Smit.
Theses external PhD-student at VU (B) Rombouts, J.O. (2015, September 04). Biologically Plausible Reinforcement Learning. VU University. Prom./coprom.: prof. dr. P.R. Roelfsema & S.M. Bohte. Seol, M. (2015, September 29). Molecular and cellular determinants of mouse corticothalamic giant terminals. VU Vrije Universiteit. Prom./coprom.: prof.dr. T.H Kuner & prof. dr. M. Verhage. Tang, D.T.P. (2015, September 28). High-throughout transcriptome sequencing: data analysis and methods development of large expression data sets. VU University. Prom./coprom.: prof. dr. A.B. Smit & P. Carninci.
Scientific papers refereed Aarts, E., Dolan, C.V., Verhage, M. & Sluis, S. van der (2015). Multilevel analysis quantifies variation in the experimental effect while optimizing power and preventing false positives. BMC Neuroscience, 16:94. doi: 10.1186/s12868-015-0228-5. Aarts, E., Maroteaux, G.P., Loos, M., Koopmans, B., Kovacevic, J., Smit, A.B., Verhage, M. & Sluis, S. van der (2015). The light spot test: Measuring anxiety in mice in an automated home-cage environment. Behavioural Brain Research, 294, 123-130. doi: 10.1016/j.bbr.2015.06.011 Agorastos, A., Kellner, M., Stiedl, O., Muhtz, C. & Demiralay, C. (2015). Blunted autonomic reactivity to pharmacological panic challenge under long-term escitalopram treatment in healthy men. International Journal of Neuropsychopharmacology, 18 (5):pyu053. doi: 10.1093/ijnp/pyu053 Andreassen, O.A., Harbo, H.F., Wang, Y., Thompson, W.K., Schork, A.J., Mattingsdal, M., Zuber, V., Bettella, F., Ripke, S., Kelsoe, J.R., Kendler, K.S., O'Donovan, M.C., Sklar, P., McEvoy, L.K., Desikan, R.S., Lie, B.A., Djurovic, S., Posthuma, D. & Dale, A.M. (2015). Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Molecular Psychiatry, 20, 207-214. doi: 10.1038/mp.2013.195 Avella Gonzalez, O.J., Mansvelder, H.D., Pelt, J. van & Ooyen, A. van (2015). H-Channels Affect Frequency, Power and Amplitude Fluctuations of Neuronal Network Oscillations. Frontiers in Computational Neuroscience, 2015 (9):141. doi: 10.3389/fncom.2015.00141 Bennis, A., Gorgels, T.G.M.F., Brink, J.B. ten, Spek, P.J. van der, Bossers, K., Heine, V.M. & Bergen, A.A. (2015). Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration. PLoS One, 10 (10):e0141597. doi: 10.1371/journal.pone.0141597 Bettencourt, C., Yebenes, J.G., Lopez-Sendon, J.L., Shomroni, O., Zhang, X.Q., Qian, S.B., Bakker, I.M.C., Heetveld, S., Ros, R., Quintans, B., Sobrido, M.J., Bevova, M.R., Jain, S., Bugiani, M., Heutink, P. & Rizzu, P. (2015). Clinical and Neuropathological Features of Spastic Ataxia in a Spanish Family with Novel Compound Heterozygous Mutations in STUB1. Cerebellum, 14 (3), 378-381. doi: 10.1007/s12311-014-0643-7 Beunders, G., Munnik, S.A. de, Aa, N.E. van der, Ceulemans, B., Voorhoeve, E., Groffen, A.J.A., Nillesen, W.M., Meijers-Heijboer, E.J., Kooy, F.R., Yntema, H.G. & Sistermans, E.A. (2015). Two male adults with pathogenic AUTS2 variants, including a two-base pair deletion, further delineate the AUTS2 syndrome. European Journal of Human Genetics, 23 (6), 803-807. doi: 10.1038/ejhg.2014.173
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Bijma, F. & Mc Assey, M.P. (2015). A clustering coefficient for complete weighted networks. Network Science. doi: 10.1017/nws.2014.26 Blankenstein, M.A. (2015). Reference intervals - ever met a normal person? Annals of Clinical Biochemistry, 52 (1), 5-6. doi: 10.1177/0004563214561563 Broek, E. van den, Dijkstra, M.J.J., Krijgsman, O., Sie, D.L.S., Haan, J.C., Traets, J.J.H., Wiel, M.A. van de, Nagtegaal, I.D., Punt, C.J.A., Carvalho, B., Ylstra, B., Abeln, S., Meijer, G.A. & Fijneman, R.J.A. (2015). High Prevalence and Clinical Relevance of Genes Affected by Chromosomal Breaks in Colorectal Cancer. PLoS One, 10 (9):e0138141. doi: 10.1371/journal.pone.0138141 Brosch, T., Neumann, H. & Roelfsema, P.R. (2015). Reinforcement Learning of Linking and Tracing Contours in Recurrent Neural Networks. PLoS Computational Biology, 11 (10):e1004489. doi: 10.1371/journal.pcbi.1004489 Brouwer, I., Giniatullina, A., Laurens, N., Weering, J.R.T. van, Bald, D., Wuite, G.J.L. & Groffen, A.J.A. (2015). Direct quantitative detection of Doc2b-induced hemifusion in optically trapped membranes. Nature Communications, 6, 8387. doi: 10.1038/ncomms9387 Bruining, H., Matsui, A, Oguro-Ando, A, Kahn, R. S., Spijker, H.M. van 't, Akkermans, G., Stiedl, O., Engeland, H. van, Koopmans, B., Lith, H.A. van, Oppelaar, H., Tieland, L, Nonkes, LJ, Yagi, T, Kaneko, R, Burbach, J.P., Yamamoto, N & Kas, M.J. (2015). Genetic mapping in mice reveals the involvement of Pcdh9 in long-term social and object recognition and sensorimotor development. Biological Psychiatry, 78 (7), 485-495. doi: 10.1016/j.biopsych.2015.01.017 Bruining, H., Passtoors, L., Goriounova, N.A., Jansen, F., Hakvoort, B., Jonge, M. de & Poil, S.S. (2015). Paradoxical Benzodiazepine Response: A Rationale for Bumetanide in Neurodevelopmental Disorders? Pediatrics, 136 (2), E539-E543. doi: 10.1542/peds.2014-4133 Bui, H.N., Sluss, P.M., Hayes, F.J., Blincko, S., Knol, D.L., Blankenstein, M.A. & Heijboer, A.C. (2015). Testosterone, free testosterone, and free androgen index in women: Reference intervals, biological variation, and diagnostic value in polycystic ovary syndrome. Clinica Chimica Acta, 450, 227-232. doi: 10.1016/j.cca.2015.08.019 Bulik-Sullivan, B.K., Loh, P.R., Finucane, H.K., Ripke, S., Yang, J., Schizophrenia Working Group of the Psychiatric Genomics Consortium, .., Posthuma, D., Patterson, N., Daly, M. J., Price, A.L. & Neale, B.M. (2015). LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nature Genetics, 47 (3), 291-295. doi: 10.1038/ng.3211 Buttler, R.M., Martens, F., Fanelli, F., Pham, H.T., Kushnir, M.M., Janssen, M.J.W., Owen, L., Taylor, A.E., Soeborg, T., Blankenstein, M.A. & Heijboer, A.C. (2015). Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone, Androstenedione, and Dehydroepiandrosterone in Serum. Clinical Chemistry, 61 (12), 1475-1483. doi: 10.1373/clinchem.2015.242859 Buttler, R.M., Martens, F., Kushnir, M.M., Ackermans, M.T., Blankenstein, M.A. & Heijboer, A.C. (2015). Simultaneous measurement of testosterone, androstenedione and dehydroepiandrosterone (DHEA) in serum and plasma using Isotope-Dilution 2-Dimension Ultra High Performance LiquidChromatography Tandem Mass Spectrometry (ID-LC-MS/MS). Clinica Chimica Acta, 438, 157-159. doi: 10.1016/j.cca.2014.08.023 Cayami, F.K., Piana, R. La, Spaendonk, R.M.L. van, Nickel, M., Bley, A., Guerrero, K., Tran, L.T., Knaap, M., Bernard, G. & Wolf, N.I. (2015). POLR3A and POLR3B Mutations in Unclassified Hypomyelination. Neuropediatrics, 46 (3), 221-227. doi: 10.1055/s-0035-1550148 Chen, N., Koopmans, F.T.W., Gordon, A, Paliukhovich, I., Klaassen, R.V., Schors, R.C. van der, Peles, E, Verhage, M., Smit, A.B. & Li, K.W. (2015). Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes. Biochimica et Biophysica Acta, 1854 (7), 827-833. doi: 10.1016/j.bbapap.2015.02.008 Crow, Y.J., Chase, D.S., Schmidt, J.L., Szynkiewicz, M., Forte, G.M.A., Gornall, H.L., Oojageer, A., Anderson, B., Pizzino, A., Helman, G., Abdel-Hamid, M.S., Abdel-Salam, G.M., Ackroyd, S., Aeby, A., Agosta, G., Albin, C., Allon-Shalev, S., Arellano, M., Ariaudo, G., Aswani, V., Babul-Hirji, R., Baildam, E.M., BahiBuisson, N., Bailey, K.M., Barnerias, C., Barth, M., Battini, R., Beresford, M.W., Bernard, G., Bianchi, M., Villemeur, T.B. de, Blair, E.M., Bloom, M., Burlina, A.B., Carpanelli, M.L., Carvalho, D.R., CastroGago, M., Cavallini, A., Cereda, C., Chandler, K.E., Chitayat, D.A., Collins, A.E., Corcoles, C.S., Cordeiro, N.J.V., Crichiutti, G., Dabydeen, L., Dale, R.C., D'Arrigo, S., Goede, C.G.E.L. De, Laet, C. de,
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Waele, L.M.H. De, Denzler, I., Desguerre, I., Devriendt, K., Rocco, M. Di, Fahey, M.C., Fazzi, E., Ferrie, C.D., Figueiredo, A., Gener, B., Goizet, C., Gowrinathan, N.R., Gowrishankar, K., Hanrahan, D., Isidor, B., Kara, L., Khan, N., King, M.D., Kirk, E.P., Kumar, R., Lagae, L., Landrieu, P., Lauffer, H., Laugel, V., Piana, R. La, Lim, M.J., Lin, J.P.S.M., Linnankivi, T., Mackay, M.T., Marom, D.R., Lourenco, C.M., McKee, S.A., Moroni, I., Morton, J.E.V., Moutard, M.L., Murray, K., Nabbout, R., Nampoothiri, S., Nunez-Enamorado, N., Oades, P.J., Olivieri, I., Ostergaard, J.R., Perez-Duenas, B., Prendiville, J.S., Ramesh, V., Rasmussen, M., Regal, L., Ricci, F., Rio, M., Knaap, M., Orcesi, S. & Rice, G.I. (2015). Characterization of Human Disease Phenotypes Associated with Mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1. American Journal of Medical Genetics Part A, 167 (2), 296-312. doi: 10.1002/ajmg.a.36887 Dagnino, B., Gariel-Mathis, M.A. & Roelfsema, P.R. (2015). Microstimulation of area V4 has little effect on spatial attention and on perception of phosphenes evoked in area V1. Journal of Neurophysiology, 113 (3), 730-739. doi: 10.1152/jn.00645.2014 Del Campo Milan, M., Oliveira, C.R., Scheper, W., Zwart, R., Korth, C., Muller-Schiffmann, A., Kostallas, G, Biverstal, H, Presto, J, Johansson, J., Hoozemans, J.J., Pereira, C.F. & Teunissen, C.E. (2015). BRI2 ectodomain affects Aβ42 fibrillation and tau truncation in human neuroblastoma cells. Cellular and Molecular Life Sciences, 72 (8), 1599-1611. doi: 10.1007/s00018-014-1769-y Desroches, C.L., Patel, J., Wang, P.X., Minassian, B., Marshall, C.R., Salomons, G. & MercimekMahmutoglu, S. (2015). Carrier frequency of guanidinoacetate methyltransferase deficiency in the general population by functional characterization of missense variants in the GAMT gene. Molecular Genetics and Genomics, 290 (6), 2163-2171. doi: 10.1007/s00438-015-1067-x Desroches, C.L., Patel, J., Wang, P.X., Minassian, B., Salomons, G., Marshall, C.R. & MercimekMahmutoglu, S. (2015). Estimated carrier frequency of creatine transporter deficiency in females in the general population using functional characterization of novel missense variants in the SLC6A8 gene. Gene, 565 (2), 187-191. doi: 10.1016/j.gene.2015.04.011 Dilekoz, E., Houben, T., Eikermann-Hearter, K., Balkaya, M., Lenselink, A.M., Whalen, M.J., Spijker, S., Ferrari, M.D., Maagdenberg, A.M.J.M. van den & Ayate, C. (2015). Migraine mutations impair hippocampal learning despite enhanced long-term potentiation. Journal of Neuroscience, 35 (8), 3397-3402. doi: 10.1523/JNEUROSCI.2630-14.2015 Dolan, C.V., Nivard, M.G., Dongen, J. van, Sluis, S. van der & Boomsma, D.I. (2015). Methylation as an epigenetic source of random genetic effects in the classical twin design. Advances in Genomics and Genetics, 5, 305-315. doi: 10.2147/AGG.S46909 Donze, S.H., Meijer, C.R., Kant, S.G., Zandwijken, G.R.J., Hout, A.H. van der, Spaendonk, R.M.L. van, Ouweland, A.M.W. van den, Wit, J.M., Losekoot, M. & Oostdijk, W. (2015). The growth response to GH treatment is greater in patients with SHOX enhancer deletions compared to SHOX defects. European Journal of Endocrinology, 173 (5), 611-621. doi: 10.1530/EJE-15-0451 Dubey, M., Bugiani, M., Ridder, M.C., Postma, N.L., Brouwers, E., Polder, E., Jacobs, J.G., Baaijen, J.C., Klooster, J., Kamermans, M., Aardse, R., Kock, C.P.J. de, Dekker, M.P, Weering, J.R.T. van, Heine, V.M., Abbink, T.E.M., Scheper, G.C., Boor, P.K.I., Lodder, J.C., Mansvelder, H.D. & Knaap, M. (2015). Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle. Annals of Neurology, 77 (11), 114-131. doi: 10.1002/ana.24307 Farina, M., Bospoort, R. van de, He, E., Persoon, C.M., Weering, J.R.T. van, Broeke, J.H.P., Verhage, M. & Toonen, R.F.G. (2015). CAPS-1 promotes fusion competence of stationary dense-core vesicles in presynaptic terminals of mammalian neurons. eLife, 4:e05438. doi: 10.7554/eLife.05438 Fernandez, E., Li, K.W., Rajan, N., Rubeis, S. de, Fiers, M., Smit, A.B., Achsel, T. & Bagni, C. (2015). FXR2P Exerts a Positive Translational Control and Is Required for the Activity-Dependent Increase of PSD95 Expression. Journal of Neuroscience, 35 (25), 9402-9408. doi: 10.1523/JNEUROSCI.480014.2015 Ferrreira, J.S., Schmidt, J, Rio, P., Aguas, R, Rooyakkers, A., Li, K.W., Smit, A.B., Graig, O.E. & Carvalho, A.L. (2015). GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. Journal of Neuroscience, 35 (22), 8462-8479. doi: 10.1523/JNEUROSCI.3567-14.2015.
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Flohr, E.L.R., Boesveldt, S., Haehner, A., Iannilli, E., Sinding, C. & Hummel, T. (2015). Time-course of trigeminal versus olfactory stimulation: Evidence from chemosensory evoked potentials. International Journal of Psychophysiology, 95 (3), 388-394. doi: 10.1016/j.ijpsycho.2015.01.014 Franic, S., Blokhuis, M.M., Dolan, C.V., Kattenberg, V.M., Pool, R., Xiao, X., Scheet, P., Ehli, E.A., Davies, G.E., Sluis, S. van der, Abdellaoui, A., Hansell, N.K., Martin, N.G., Hudziak, J.J., Beijsterveldt, C.E.M. van, Swagerman, S.C., Hulshoff Pol, H.E., Geus, E.J.C. de, Bartels, M., Ropers, H.-H., Hottenga, J.J. & Boomsma, D.I. (2015). Intelligence: shared genetic basis between Mendelian disorders and a polygenic trait. European Journal of Human Genetics, 23 (10), 1378-1383. doi: 10.1038/ejhg.2015.3 Geerts, C.J., Plomp, J.J., Koopmans, B., Loos, M., Pijl, EM van der, Valk, M.A. van der, Verhage, M. & Groffen, A.J.A. (2015). Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates. Brain Structure and Function, 220 (4), 1971-1982. doi: 10.1007/s00429-014-0766-0 Geytenbeek, J.J.M., Vermeulen, R.J., Becher, J.G. & Oostrom, K.J. (2015). Comprehension of spoken language in non-speaking children with severe cerebral palsy: an explorative study on associations with motor type and disabilities. Developmental Medicine and Child Neurology, 57 (3), 294-300. doi: 10.1111/dmcn.12619 Geytenbeek, J.J., Oostrom, K.J., Harlaar, L., Becher, J.G., Knol, D.L., Barkhof, F., Pinto, P.S. & Vermeulen, R.J. (2015). Language comprehension in nonspeaking children with severe cerebral palsy: Neuroanatomical substrate? European Journal of Paediatric Neurology, 19 (5), 510-520. doi: 10.1016/j.ejpn.2015.06.001 Geytenbeek, J.J.M., Heim, M.J.M., Knol, D.L., Vermeulen, R.J. & Oostrom, K.J. (2015). Spoken language comprehension of phrases, simple and compound-active sentences in non-speaking children with severe cerebral palsy. International Journal of Language and Communication Disorders, 50 (4), 499-515. doi: 10.1111/1460-6984.12151 Giniatullina, A., Maroteaux, G.P., Geerts, C.J., Koopmans, B., Loos, M., Klaassen, R.V., Chen, N., Schors, R.C. van der, Nierop, P. van, Li, K.W., Jong, A.P.H. de, Altrock, W.D., Cornelisse, L.N., Toonen, R.F.G., Sluis, S. van der, Sullivan, P.F., Stiedl, O., Posthuma, D., Smit, A.B., Groffen, A.J.A. & Verhage, M. (2015). Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences. Neuroscience, 300, 518538. doi: 10.1016/j.neuroscience.2015.05.047 Golovko, T., Min, R., Lozovaya, N., Falconer, C., Yatsenko, N., Tsintsadze, T., Tsintsadze, V., Ledent, C., Harvey, R.J., Belelli, D., Lambert, J.J., Rozov, A. & Burnashev, N. (2015). Control of Inhibition by the Direct Action of Cannabinoids on GABA(A) Receptors. Cerebral Cortex, 25 (9), 2440-2455. doi: 10.1093/cercor/bhu045 Gutierrez, M., Thiffault, I., Guerrero, K., Martos-Moreno, G.A., Tran, L.T., Benko, W., Knaap, M., Spaendonk, R.M.L. van, Wolf, N.I. & Bernard, G. (2015). Large exonic deletions in POLR3B gene cause POLR3-related leukodystrophy. Orphanet journal of rare diseases, 10, 69. doi: 10.1186/s13023-015-0279-9 Hamilton, E.M.C., Wolf, N.I. & Knaap, M.S. van der (2015). Reply: A novel TUBB4A mutation suggests that genotype-phenotype correlation of H-ABC syndrome needs to be revisited. Brain, 138:E371. doi: 10.1093/brain/awu404 Hamilton, E.M.C., Wolf, N.I. & Knaap, M.S. van der (2015). Reply: TUBB4A novel mutation reinforces the genotype-phenotype correlation of hypomyelination with atrophy of the basal ganglia and cerebellum. Brain, 138:e328. doi: 10.1093/brain/awu243 Hanagasi, H.A., Bilgic, B., Abbink, T.E.M., Hanagasi, F., Tufekcioglu, Z., Gurvit, H., Basak, N., Knaap, M. & Emre, M. (2015). Secondary paroxysmal kinesigenic dyskinesia associated with CLCN2 gene mutation. Parkinsonism and Related Disorders, 21 (5), 544-546. doi: 10.1016/j.parkreldis.2015.02.013 Helman, G., Haren, K. van, Bonkowsky, J.L., Bernard, G., Pizzino, A., Braverman, N., Suhr, D., Patterson, M.C., Fatemi, S.A., Leonard, J., Knaap, M., Back, S.A., Damiani, S., Goldman, S.A., Takanohashi, A., Petryniak, M., Rowitch, D., Messing, A., Wrabetz, L., Schiffmann, R., Eichler, F., Escolar, M.L. & Vanderver, A. (2015). Disease specific therapies in leukodystrophies and leukoencephalopathies. Molecular Genetics and Metabolism, 114 (4), 527-536. doi: 10.1016/j.ymgme.2015.01.014
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Mohan, H., Verhoog, M.B., Doreswamy, K.K., Eyal, G., Aardse, R., Lodder, B.N., Goriounova, N.A., Asamoah, B., Brakspear, A.B., Groot, C., Sluis, S. van der, Testa-Silva, G., Obermayer, J.M.G., Boudewijns, Z.S.R.M., Narayanan, R.T., Baayen, J.C., Segev, I, Mansvelder, H.D. & Kock, C.P.J. de (2015). Dendritic and Axonal Architecture of Individual Pyramidal Neurons across Layers of Adult Human Neocortex. Cerebral Cortex, 25 (12), 4839-4853. doi: 10.1093/cercor/bhv188 Huemer, M., Karall, D., Schossig, A., Abdenur, J.E., Jasmi, F. Al, Biagosch, C., Distelmaier, F., Freisinger, P., Graham, B.H., Haack, T.B., Hauser, N., Hertecant, J., Ebrahimi-Fakhari, D., Konstantopoulou, V., Leydiker, K., Lourenco, C.M., Scholl-Burgi, S., Wilichowski, E., Wolf, N.I., Wortmann, S.B., Taylor, R.W., Mayr, J.A., Bonnen, P.E., Sperl, W., Prokisch, H. & McFarland, R. (2015). Clinical, morphological, biochemical, imaging and outcome parameters in 21 individuals with mitochondrial maintenance defect related to FBXL4 mutations. Journal of Inherited Metabolic Disease, 38 (5), 905-914. doi: 10.1007/s10545-015-9836-6 Jacobsen, K.K., Nievergelt, C.M., Zayats, T., Greenwood, T.A., Anttila, V., Akiskal, H.S., Ligthart, R.S.L., Hottenga, J.J., Vink, J.M., Penninx, B.W.J.H., Boomsma, D.I., Haavik, J., Fasmer, O.B., Kelsoe, J.R., Johansson, S. & Oedegaard, K.J. (2015). Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder. Journal of Affective Disorders, 172, 453-461. doi: 10.1016/j.jad.2014.10.004 Jansen, A.G., Mous, S.E., White, T., Posthuma, D. & Polderman, J.C. (2015). What twin studies tell us about the heritability of brain development, morphology, and function: a review. Neuropsychology Review, 25 (1), 27-46. doi: 10.1007/s11065-015-9278-9 Jany, P.L., Agosta, G.E., Benko, W.S., Eickhoff, J.C., Keller, S.R., Koehler, W., Koeller, D., Mar, S., Naidu, S., Ness, J. Marie, Pareyson, D., Renaud, D.L., Salsano, E., Schiffmann, R., Simon, J., Vanderver, A., Eichler, F., Knaap, M. & Messing, A. (2015). CSF and Blood Levels of GFAP in Alexander Disease(1,2,3). eNeuro, 2 (5), ENEURO.0080-15.2015. doi: 10.1523/ENEURO.0080-15.2015 Kallen, L.R. van der, Eggers, R., Ehlert, E.M., Verhaagen, J., Smit, A.B. & Kesteren, R.E. van (2015). Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo. PLoS One, 10 (5):e0127163. doi: 10.1371/journal.pone.0127163 Kamp, J.M. van de, Errami, A., Howidi, M., Anselm, I., Winter, S., Phalin-Roque, J., Osaka, H., Dooren, S.J.M. van, Mancini, G.M., Steinberg, S.J. & Salomons, G. (2015). Genotype-phenotype correlation of contiguous gene deletions of SLC6A8, BCAP31 and ABCD1. Clinical Genetics, 87 (2), 141-147. doi: 10.1111/cge.12355 Kariminejad, A., Rajaee, A., Ashrafi, M.R., Alizadeh, H., Tonekaboni, S.H., Malamiri, R.A., Ghofrani, M., Karimzadeh, P., Mohammadi, M.M., Baghalshooshtari, A., Bozorgmehr, B., Kariminejad, M.H., Postma, N., Abbink, G.E.M. & Knaap, M. (2015). Eight novel mutations in MLC1 from 18 Iranian patients with megalencephalic leukoencephalopathy with subcortical cysts. European Journal of Medical Genetics, 58 (2), 71-74. doi: 10.1016/j.ejmg.2014.12.004 Kedar, G.H., Munch, A.S., Weering, J.R.T. van, Malsam, J., Scheutzow, A., Wit, H. de, Houy, S., Tawfik, B., Sollner, T.H., Sorensen, J.B. & Verhage, M. (2015). A Post-Docking Role of Synaptotagmin 1-C2B Domain Bottom Residues R398/399 in Mouse Chromaffin Cells. Journal of Neuroscience, 35 (42), 14172-14182. doi: 10.1523/JNEUROSCI.1911-15.2015 Kelmemi, W., Teeuw, M.E., Bochdanovits, Z., Ouburg, S., Jonker, M.A., Alkuraya, F., Hashem, M., Kayserili, H., Haeringen, A. van, Sheridan, E., Masri, A., Cobben, J.M., Rizzu, P., Kostense, P.J., Dommering, C.J., Henneman, L., Bouhamed-Chaabouni, H., Heutink, P., Kate, L.P. ten & Cornel, M.C. (2015). Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome. BMC Medical Genetics, 16:50. doi: 10.1186/s12881-015-0191-0 Kevelam, S.H., Taube, J.R., Spaendonk, R.M.L. van, Bertini, E., Sperle, K., Tarnopolsky, M., Tonduti, D., Valente, E.M., Travaglini, L., Sistermans, E.A., Bernard, G., Catsman-Berrevoets, C.E., Karnebeek, C.D.M. van, Ostergaard, J.R., Friederich, R.L., Elsaid, M.F., Schieving, J.H., Tarailo-Graovac, M., Orcesi, S., Steenweg, M.E., Berkel, C.G.M. van, Waisfisz, Q., Abbink, G.E.M., Knaap, M., Hobson, G.M. & Wolf, N.I. (2015). Altered PLP1 splicing causes hypomyelination of early myelinating structures. Annals of Clinical and Translational Neurology, 2 (6), 648-661. doi: 10.1002/acn3.203
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Kevelam, S.H., Bierau, J., Salvarinova, R., Agrawal, S., Honzik, T., Visser, D., Weiss, M.M., Salomons, G., Abbink, T.E.M., Waisfisz, Q. & Knaap, M.S. van der (2015). Recessive ITPA Mutations Cause an Early Infantile Encephalopathy. Annals of Neurology, 78 (4), 649-658. doi: 10.1002/ana.24496 Klok, M.D., Bakels, H.S., Postma, N.L., Spaendonk, R.M.L. van, Knaap, M.S. van der & Bugiani, M. (2015). Interferon-alpha and the calcifying microangiopathy in Aicardi-Goutieres syndrome. Annals of Clinical and Translational Neurology, 2 (7), 774-779. doi: 10.1002/acn3.213 Konigs, M., Weeda, W.D., Heurn, L.W.E. van, Vermeulen, R.J., Goslings, J.C., Luitse, J.S.K., Poll-The, B.T., Beelen, A., Wees, M., Kemps, R.J.J.K., Catsman-Berrevoets, C.E. & Oosterlaan, J. (2015). Impaired visual integration in children with traumatic brain injury: an observational study. PLoS One, 10 (12):e0144395. doi: 10.1371/journal.pone.0144395 Konigs, M., Heij, H.A., Sluijs, J.A. van der, Vermeulen, R.J., Goslings, J.C., Luitse, J.S.K., Beelen, A., Wees, M., Kemps, R.J.J.K., Catsman-Berrevoets, C.E. & Oosterlaan, J. (2015). Pediatric Traumatic Brain Injury and Attention Deficit. Pediatrics, 136 (3), 534-541. doi: 10.1542/peds.2015-0437 Lapalme-Remis, S., Lewis, E.C., Meulemeester, C. De, Chakraborty, P., Gibson, K.M., Torres, C., Guberman, A., Salomons, G., Jakobs, C., Ali-Ridha, A., Parviz, M. & Pearl, P.L. (2015). Natural history of succinic semialdehyde dehydrogenase deficiency through adulthood. Neurology, 85 (10), 861-865. doi: 10.1212/WNL.0000000000001906 Lee, S.H., Byrne, E.M., Hultman, C. M., K채hler, A., Vinkhuyzen, A.A.E., Ripke, S., Andreassen, O.A., Frisell, T., Gusev, A., Hu, X., Karlsson, R., Mantzioris, V., McGrath, J.J., Mehta, D., Stahl, E.A., Zhao, G., Kendler, K.S., Sullivan, P.F., Price, A.L., O'Donovan, M., Okada, Y., Mowry, B. J., Raychaudhuri, S., Wray, N.R. & Posthuma, D. (2015). New data an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology, 44 (5), 1706-1721. doi: 10.1093/ije/dyv136 Leeuw, C.A. de, Goudriaan, A., Smit, A.B., Yu, D., Mathews, C.A., Scharf, J.M., Verheijen, M.H.G. & Posthuma, D. (2015). Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis. European Journal of Human Genetics, 23 (11), 1519-1522. doi: 10.1038/ejhg.2015.22 Leeuw, C.A. de, Mooij, J.M., Heskes, T. & Posthuma, D. (2015). MAGMA: generalized gene-set analysis of GWAS data. PLoS Computational Biology, 11 (4):e1004219. doi: 10.1371/journal.pcbi.1004219 Lenselink, A.M., Rotaru-Marcu, D.C., Li, K.W., Nierop, P. van, Rao-Ruiz, P., Loos, M., Schors, R.C. van der, Gouwenberg, Y., Wortel, J., Mansvelder, H.D., Smit, A.B. & Spijker, S. (2015). Strain Differences in Presynaptic Function: Proteomics, Ultrastructure, and Physiology of Hippocampal Synapses in DBA/2J AND C57Bl/6J mice.. Journal of Biological Chemistry, 290 (25), 15635-15645. doi: 10.1074/jbc.M114.628776 Lips, E.S., Kooyman, M., Leeuw, C.A. de & Posthuma, D. (2015). JAG: A Computational Tool to Evaluate the Role of Gene-Sets in Complex Traits. Genes, 6 (2), 238-251. doi: 10.3390/genes6020238 Loos, M., Koopmans, B., Aarts, E., Sluis, S. van der, Smit, A.B. & Verhage, M. (2015). Within-strain variation in behavior differs consistently between common inbred strains of mice. Genome Research, 26 (7-8), 348-354. doi: 10.1007/s00335-015-9578-7 Lorteije, J.A.M., Zylberberg, A., Ouellette, B.G., Zeeuw, C.I., Sigman, M. & Roelfsema, P.R. (2015). The Formation of Hierarchical Decisions in the Visual Cortex. Neuron, 87 (6), 1344-1356. doi: 10.1016/j.neuron.2015.08.015 Meijer, M., Cijsouw, A., Toonen, R.F.G. & Verhage, M. (2015). Synaptic Effects of Munc18-1 Alternative Splicing in Excitatory Hippocampal. PLoS One, 10 (9):e0138950. doi: 10.1371/journal.pone.0138950 Mendes, M.I.S., Smith, D.E.C., Vicente, J.B., Almeida, I. Tavares de, Ben-Omran, T., Salomons, G., Rivera, I.A., Leandro, P. & Blom, H.J. (2015). Small aminothiol compounds improve the function of Arg to Cys variant proteins: effect on the human cystathionine beta-synthase p.R336C. Human Molecular Genetics, 24 (25), 7339-7348. doi: 10.1093/hmg/ddv431 Meng, B., Ip, N.C., Prestwood, L.J., Abbink, G.E.M. & Lever, A.M.L. (2015). Evidence that the endosomal sorting complex required for transport-II (ESCRT-II) is required for efficient human immunodeficiency virus-1 (HIV-1) production. Retrovirology, 12:72. doi: 10.1186/s12977-0150197-x
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Meredith, R.M. (2015). Sensitive and critical periods during neurotypical and aberrant neurodevelopment: A framework for neurodevelopmental disorders. Neuroscience and Biobehavioral Reviews, 50, 180-188. doi: 10.1016/j.neubiorev.2014.12.001 Meuwissen, M.E.C., Halley, D.J.J., Smit, L.S., Lequin, M.H., Cobben, J.M., Coo, R. de, Harssel, J. van, Sallevelt, S., Woldringh, G., Knaap, M., Vries, L.S. de & Mancini, G.M.S. (2015). The expanding phenotype of COL4A1 and COL4A2 mutations: clinical data on 13 newly identified families and a review of the literature. Genetics in Medicine, 17 (11), 843-853. doi: 10.1038/gim.2014.210 Michel, S., Keller, M.A., Wamelink, M.M.C. & Ralser, M. (2015). A haploproficient interaction of the transaldolase paralogue NQM1 with the transcription factor VHR1 affects stationary phase survival and oxidative stress resistance. Bmc genetics, 16:13. doi: 10.1186/s12863-015-0171-6 Morkrid, L., Rowe, A.D., Elgstoen, K.B.P., Olesen, J.H., Ruijter, G., Hall, P.L., Tortorelli, S., Schulze, A., Kyriakopoulou, L., Wamelink, M.M.C., Kamp, J.M. van de, Salomons, G.S. & Rinaldo, P. (2015). Continuous Age- and Sex-Adjusted Reference Intervals of Urinary Markers for Cerebral Creatine Deficiency Syndromes: A Novel Approach to the Definition of Reference Intervals. Clinical Chemistry, 61 (5), 760-768. doi: 10.1373/clinchem.2014.235564 Narayanan, R.T., Egger, R., Johnson, A.S., Mansvelder, H.D., Sakmann, B., Kock, C.P.J. de & Oberlaender, M. (2015). Beyond Columnar Organization: Cell Type- and Target Layer-Specific Principles of Horizontal Axon Projection Patterns in Rat Vibrissal Cortex. Cerebral Cortex, 25 (11), 4450-4468. doi: 10.1093/cercor/bhv053 Neerincx, M., Sie, D.L.S., Wiel, M.A. van de, Grieken, N.C.T. van, Burggraaf, J.D., Dekker, H., Eijk, P.P., Ylstra, B., Verhoef, C., Meijer, G.A., Buffart, T.E. & Verheul, H.M.W. (2015). MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing. Oncogenesis, 4:e170. doi: 10.1038/oncsis.2015.29 Nefs, G., Donga, E., Someren, E.J.W. van, Bot, M., Speight, J. & Pouwer, F. (2015). Subjective sleep impairment in adults with type 1 or type 2 diabetes: Results from Diabetes MILES-The Netherlands. Diabetes Research and Clinical Practice, 109 (3), 466-475. doi: 10.1016/j.diabres.2015.07.008 Nienborg, H. & Roelfsema, P.R. (2015). Belief states as a framework to explain extra-retinal influences in visual cortex. Current Opinion in Neurobiology, 32, 45-52. doi: 10.1016/j.conb.2014.10.013 Obulkasim, A., Meijer, G.A. & Wiel, M.A. van de (2015). Semi-supervised adaptive-height snipping of the hierarchical clustering tree. BMC Bioinformatics, 16:15. doi: 10.1186/s12859-014-0448-1 Omrani, A., Vaart, A. Van der, Mientjes, E., Woerden, G.M., Hojjati, M.R., Li, K.W., Gutmann, D.H., Levelt, C.N., Smit, A.B., Silva, A.J., Kushner, S.A. & Elgersma, Y. (2015). HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1. Molecular Psychiatry, 20 (11), 1311-1321. doi: 10.1038/mp.2015.48. Onuki, Y., Someren, E.J.W. van, Zeeuw, C.I. & Werf, Y.D. van der (2015). Hippocampal–Cerebellar Interaction During Spatio-Temporal Prediction. Cerebral Cortex, 25 (2), 313-321. doi: 10.1093/cercor/bht221 Otvos, R.A., Iyer, J.K., Elk, R. van, Ulens, C., Niessen, W.M., Somsen, G.W., Kini, R.M., Smit, A.B. & Kool, J. (2015). Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Toxins, 7 (7), 2336-2353. doi: 10.3390/toxins7072336 O’Dushlaine, C., Rossin, L., Lee, P.H., Duncan, L., Parikshak, N.N., Newhouse, S., Ripke, S., Neale, B.M., Purcell, S.M., Posthuma, D., Boomsma, D.I., Geus, E.J.C. de, Hottenga, J.J., Krabbendam, A.C., Middeldorp, C.M., Penninx, B.W.J.H., Sergeant, J.A., Smit, J.H., Grootheest, G., Willemsen, G., Holmes, P. & Breen, G. (2015). Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience, 18 (2), 199-209. doi: 10.1038/nn.3922 Parikh, S., Bernard, G., Leventer, R.J., Knaap, M., Hove, J. ten, Pizzino, A., McNeill, N.H., Helman, G., Simons, C., Schmidt, J.L., Rizzo, W.B., Patterson, M.C., Taft, R.J. & Vanderver, A. (2015). A clinical approach to the diagnosis of patients with leukodystrophies and genetic leukoencephelopathies. Molecular Genetics and Metabolism, 114 (4), 501-515. doi: 10.1016/j.ymgme.2014.12.434 Pol, L.A. van de, Wolf, N.I., Weissenbruch, M.M. van, Stam, C.J., Weiss, J.M., Waisfisz, Q., Kevelam, S.H., Bugiani, M., Kamp, J.M. van de & Knaap, M. (2015). Early-Onset Severe Encephalopathy with
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Epilepsy: The BRAT1 Gene Should Be Added to the List of Causes. Neuropediatrics, 46 (6), 392-400. doi: 10.1055/s-0035-1564791 Pol, L.A. van de, Doeveren, T.E.M. van, Kuip, M. van der, Wolf, N.I. & Vermeulen, R.J. (2015). Pediatric Neurocysticercosis: Three Cases Presented in the Netherlands with Divergent Clinical Presentations. Neuropediatrics, 46 (2), 130-133. doi: 10.1055/s-0034-1399753 Pol, R.J. van der, Benninga, M., Magre, J., Maldergem, L. van, Rotteveel, J., Knaap, M. & Meij, T.G. de (2015). Berardinelli-Seip syndrome and achalasia: a shared pathomechanism? European Journal of Pediatrics, 174 (7), 975-980. doi: 10.1007/s00431-015-2556-y Polderman, J.C., Benyamin, B., Leeuw, C.A. de, Sullivan, P.F., Bochoven, A., Visscher, P. M. & Posthuma, D. (2015). Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nature Genetics, 47 (7), 702-709. doi: 10.1038/ng.3285 Poretti, A., Wolf, N.I. & Boltshauser, E. (2015). Differential Diagnosis of Cerebellar Atrophy in Childhood: An Update. Neuropediatrics, 46 (6), 359-370. doi: 10.1055/s-0035-1564620 Posset, R., Opp, S., Struys, E.A., Volkl, A., Mohr, H., Hoffmann, G.F., Kolker, S., Sauer, S.W. & Okun, J.G. (2015). Understanding cerebral L-lysine metabolism: the role of L-pipecolate metabolism in Gcdhdeficient mice as a model for glutaric aciduria type I. Journal of Inherited Metabolic Disease, 38 (2), 265-272. doi: 10.1007/s10545-014-9762-z Prasun, P., Young, S., Salomons, G., Werneke, A., Jiang, Y.H., Struijs, E.A., Paige, M., Avantaggiati, M.L. & McDonald, M. (2015). Expanding the Clinical Spectrum of Mitochondrial Citrate Carrier (SLC25A1) Deficiency: Facial Dysmorphism in Siblings with Epileptic Encephalopathy and Combined D,L-2Hydroxyglutaric Aciduria. JIMD Reports, 19, 111-115. doi: 10.1007/8904_2014_378 Rao-Ruiz, P., Carney, K.E., Pandya, N.J., Loo, R.J., Verheijen, M.H.G., Nierop, P. van, Smit, A.B. & Spijker, S. (2015). Time-dependent changes in the mouse hippocampal synaptic membrane proteome after contextual fear conditioning. Hippocampus, 25 (11), 1250-1261. doi: 10.1002/hipo.22432. Rappard, D.F. van, Boelens, J.J. & Wolf, N.I. (2015). Metachromatic leukodystrophy: Disease spectrum and approaches for treatment. Baillière's Best Practice and Research. Clinical Endocrinology and Metabolism, 29 (2), 261-273. doi: 10.1016/j.beem.2014.10.001 Reddy, L., Poncet, M., Self, M.W., Peters, J.C., Douw, L., Dellen, E. van, Claus, S., Reijneveld, J.C., Baayen, J.C. & Roelfsema, P.R. (2015). Learning of anticipatory responses in single neurons of the human medial temporal lobe. Nature Communications, 6:8556. doi: 10.1038/ncomms9556 Remmelink, E., Loos, M., Koopmans, B., Aarts, E., Sluis, S. van der, Smit, A.B. & Verhage, M. (2015). A 1night operant learning task without food-restriction differentiates among mouse strains in an automated home-cage environment. Behavioural Brain Research, 283, 53-60. doi: 10.1016/j.bbr.2015.01.020 Romani, M., Mancini, F., Micalizzi, A., Poretti, A., Miccinilli, E., Accorsi, P., Avola, E., Bertini, E., Borgatti, R., Romaniello, R., Ceylaner, S., Coppola, G., D'Arrigo, S., Giordano, L., Janecke, A.R., Lituania, M., Ludwig, K., Martorell, L., Mazza, T., Odent, S., Pinelli, L., Poo, P., Santucci, M., Signorini, S., Simonati, A., Spiegel, R., Stanzial, F., Steinlin, M., Tabarki, B., Wolf, N.I., Zibordi, F., Boltshauser, E. & Valente, E.M. (2015). Oral-facial-digital syndrome type VI: is C5orf42 really the major gene? Human Genetics, 134 (1), 123-126. doi: 10.1007/s00439-014-1508-3 Rombouts, J.O., Bohte, S.M., Martinez-Trujillo, J. & Roelfsema, P.R. (2015). A learning rule that explains how rewards teach attention. Visual Cognition, 23 (1-2), 179-205. doi: 10.1080/13506285.2015.1010462 Rombouts, J.O., Bohte, S.M. & Roelfsema, P.R. (2015). How Attention Can Create Synaptic Tags for the Learning of Working Memories in Sequential Tasks. PLoS Computational Biology, 11 (3):e1004060. doi: 10.1371/journal.pcbi.1004060 Saiepour, M.H., Rajendran, R., Omrani, A., Ma, W., Tao, H.W., Heimel, J.A. & Levelt, C.N. (2015). Ocular Dominance Plasticity Disrupts Binocular Inhibition-Excitation Matching in Visual Cortex. Current Biology, 25 (6), 713-721. doi: 10.1016/j.cub.2015.01.024 Schotten, S., Meijer, M., Walter, A.M., Huson, V.W.J., Mamer, L., Kalogreades, L., Veer, M.T., Ruiter, M., Brose, N., Rosenmund, C., Sorensen, J.B., Verhage, M. & Cornelisse, L.N. (2015). Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate. eLife, 4:e05531. doi: 10.7554/eLife.09036.
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Schreiber, J., Végh, M.J., Dawitz, J., Kroon, T., Loos, M., Labonté, D., Li, K.W., Nierop, P. van, Diepen, M.T. van, Zeeuw, C.I., Kneussel, M., Meredith, R.M., Smit, A.B. & Kesteren, R.E. van (2015). Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels. Journal of Cell Biology, 211, 569-586. doi: 10.1083/jcb.201506048 Seigers, R., Loos, M., Tellingen, O. van, Boogerd, W., Smit, A.B. & Schagen, S.B. (2015). Cognitive impact of cytotoxic agents in mice. Psychopharmacology, 232 (1), 17-37. doi: 10.1007/s00213-014-3636-9 Self, M.W., Mookhoek, A., Tjalma, N. & Roelfsema, P.R. (2015). Contextual effects on perceived contrast: Figure-ground assignment and orientation contrast. Journal of Vision, 15 (2):2. doi: 10.1167/15.2.2 Self, M.W. & Roelfsema, P.R. (2015). Scene perception in early vision: Figure-ground organization in the lateral geniculate nucleus. Proceedings of the National Academy of Sciences of the United States of America, 112 (22), 6784-6785. doi: 10.1073/pnas.1507097112 Sluis, S. van der, Dolan, C.V., Li, J., Song, Y., Sham, P., Posthuma, D. & Li, M. (2015). MGAS: a powerful tool for multivariate gene-based genome-wide association analysis. Bioinformatics, 31 (7), 1007-1015. doi: 10.1093/bioinformatics/btu783 Someren, E.J. van, Cirelli, C., Dijk, D.J., Cauter, E. Van, Schwartz, S. & Chee, M.W.L. (2015). Disrupted Sleep: From Molecules to Cognition. Journal of Neuroscience, 35 (41), 13889-13895. doi: 10.1523/JNEUROSCI.2592-15.2015 Stiedl, O., Pappa, E., Konradssson-Geuken, A. & Ogren, S.O. (2015). The role of the serotonin receptor subtypes 5-HT1A and 5-HT7 and its interaction in emotional learning and memory. Frontiers in Pharmacology, 6:162. doi: 10.3389/fphar.2015.00162 Stincone, A., Prigione, A., Cramer, T., Wamelink, M.M.C., Campbell, K., Cheung, E., Olin-Sandoval, V., Gruning, N.M., Kruger, A., Alam, M.T., Keller, M.A., Breitenbach, M., Brindle, K.M., Rabinowitz, J.D. & Ralser, M. (2015). The return of metabolism: biochemistry and physiology of the pentose phosphate pathway. Biological Reviews, 90 (3), 927-963. doi: 10.1111/brv.12140 Tan-Sindhunata, M.B., Matthijssen, I.B., Smit, M., Baas, F., Vries, J.I.P. de, Voorn, J.P. van der, Kluijt, I., Hagen, M.A., Blom, E.W., Sistermans, E.A., Heijboer-Meijers, J.E., Waisfisz, Q., Weiss, M.M. & Groffen, A.J.A. (2015). Identification of a Dutch founder mutation in MUSK causing fetal akinesia deformation sequence. European Journal of Human Genetics, 23 (9), 1151-1157. doi: 10.1038/ejhg.2014.273 Thiffault, I., Wolf, N.I., Forget, D., Guerrero, K., Tran, L.T., Choquet, K., Lavalleee-Adam, M., Poitras, C., Brais, B., Yoon, G., Sztriha, L., Webster, R.I., Timmann, D., Warrenburg, B.P.V. de, Seeger, J., Zimmermann, A., Mate, A., Goizet, C., Fung, E., Knaap, M., Fribourg, S., Vanderver, A., Simons, C., Taft, R.J., Yates, J.R., Coulombe, B. & Bernard, G. (2015). Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III. Nature Communications, 6, 7623. doi: 10.1038/ncomms8623 Tillema, J.M., Derks, M.G.M., Pouwels, P.J.W., Graaf, P. de, Rappard, D.F. van, Barkhof, F., Steenweg, M.E., Knaap, M.S. van der & Wolf, N.I. (2015). Volumetric MRI data correlate to disease severity in metachromatic leukodystrophy. Annals of Clinical and Translational Neurology, 2 (9), 932-940. doi: 10.1002/acn3.232 Upton, K.R., Gerhardt, D.J., Jesuadian, J.S., Richardson, S.R., Sanchez-Luque, F.J., Bodea, G.O., Ewing, A.D., Salvador-Palomeque, C., Knaap, M., Brennan, P.M., Vanderver, A. & Faulkner, G.J. (2015). Ubiquitous L1 Mosaicism in Hippocampal Neurons. Cell, 161 (2), 228-239. doi: 10.1016/j.cell.2015.03.026 Vanderver, A., Prust, M., Tonduti, D., Mochel, F., Hussey, H.M., Helman, G., Garbern, J., Eichler, F., Labauge, P., Aubourg, P., Rodriguez, D., Patterson, M.C., Hove, J.LK. van, Schmidt, J, Wolf, N.I., Boespflug-Tanguy, O., Schiffmann, R. & Knaap, M. (2015). Case definition and classification of leukodystrophies and leukoencephalopathies. Molecular Genetics and Metabolism, 114 (4), 494500. doi: 10.1016/j.ymgme.2015.01.006 Vanderver, A., Prust, M., Kadom, N., Demarest, S., Crow, Y.J., Helman, G., Orcesi, S., Piana, R. La, Uggetti, C., Wang, J.C., Gordisch-Dressman, H., Knaap, M. & Livingston, J.H. (2015). Early-Onset AicardiGoutieres Syndrome: Magnetic Resonance Imaging (MRI) Pattern Recognition. Journal of Child Neurology, 30 (10), 1343-1348. doi: 10.1177/0883073814562252 Verbeek, N.E., Maas, N.A.T. van der, Sonsma, A.C.M., Ippel, E., Bondt, P.E.V.D., Hagebeuk, E., Jansen, F.E., Geesink, H.H., Braun, K.P., Louw, A. de, Augustijn, P.B., Neuteboom, R.F., Schieving, J.H., Stroink,
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H., Vermeulen, R.J., Nicolai, J., Brouwer, O.F., Kempen, M. van, Kovel, C.G.F. de, Kemmeren, J.M., Koeleman, B.P.C., Knoers, N.V., Lindhout, D., Gunning, W.B. & Brilstra, E.H. (2015). Effect of vaccinations on seizure risk and disease course in Dravet syndrome. Neurology, 85 (7), 596-603. doi: 10.1212/WNL.0000000000001855 Vogel, K.R., Ainslie, G.R., Jansen, E.E.W., Salomons, G. & Gibson, K.M. (2015). Torin 1 partially corrects vigabatrin-induced mitochondrial increase in mouse. Annals of Clinical and Translational Neurology, 2 (6), 699-706. doi: 10.1002/acn3.200 Vries, T.J. de, Schoenmaker, T., Aerts, D., Grevers, L.C., Souza, P.P.C., Nazmi, K., Wiel, M.A. van de, Ylstra, B., Lent, P.L. van, Leenen, P.J.M. & Everts, V. (2015). M-CSF Priming of Osteoclast Precursors Can Cause Osteoclastogenesis-Insensitivity, Which Can be Prevented and Overcome on Bone. Journal of Cellular Physiology, 230 (1), 210-225. doi: 10.1002/jcp.24702 Wamelink, M.M.C., Ramos, R.J.J.F., Elzen, A.P.M. van den, Ruijter, G.J.G., Bonte, R., Diogo, L., Garcia, P., Neves, N., Nota, B., Haschemi, A., Almeida, I.T. de & Salomons, G. (2015). First two unrelated cases of isolated sedoheptulokinase deficiency: A benign disorder? Journal of Inherited Metabolic Disease, 38 (5), 889-894. doi: 10.1007/s10545-014-9809-1 Wiemhoefer, A, Stargardt, A, Linden, W.A., Renner, M.C., Kesteren, R.E. van, Stap, J., Raspe, M.A., Tomkinson, B., Kessels, H.W., Ovaa, H., Overkleeft, H.S., Florea, B. & Reits, E.A. (2015). Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2. Molecular and Cellular Proteomics, 14, 2177-2193. doi: 10.1074/mcp.M114.043331 Williams, C.A., Abbink, G.E.M., Jeang, K.T. & Lever, A.M.L. (2015). Identification of RNA helicases in human immunodeficiency virus 1 (HIV-1) replication - a targeted small interfering RNA library screen using pseudotyped and WT HIV-1. Journal of General Virology, 96 (Pt 6), 1484-1489. doi: 10.1099/vir.0.000092 Wolf, N.I., Toro, C., Kister, I., Latif, K. Abd, Leventer, R., Pizzino, A., Simons, C., Abbink, G.E.M., Taft, R.J., Knaap, M.S. van der & Vanderver, A. (2015). DARS-associated leukoencephalopathy can mimic a steroid-responsive neuroinflammatory disorder. Neurology, 84 (3), 226-230. doi: 10.1212/WNL.0000000000001157 Wolf, N.I. & Bernard, G. (2015). Mutations in RNF216 do not cause 4H syndrome. Parkinsonism and Related Disorders, 21 (11), 1387-1388. doi: 10.1016/j.parkreldis.2015.09.014 Wortmann, S.B., Hasselt, P.M. van, Baric, I., Burlina, A., Darin, N., Horster, F., Coker, M., Ucar, S.K., Krumina, Z., Naess, K., Ngu, L.H., Pronicka, E., Riordan, G., Santer, R., Wassmer, E., Zschocke, J., Schiff, M., Meirleir, L. de, Alowain, M.A., Smeitink, J.A.M., Morava, E., Kozicz, T., Wevers, R.A., Wolf, N.I. & Willemsen, M.A. (2015). Eyes on MEGDEL: Distinctive Basal Ganglia Involvement in Dystonia Deafness Syndrome. Neuropediatrics, 46 (2), 98-103. doi: 10.1055/s-0034-1399755 Zuurbier, L.A., Ikram, M.A., Luik, A.I., Hofman, A., Someren, E.J.W. van, Vernooij, M.W. & Tiemeier, H. (2015). Cerebral small vessel disease is related to disturbed 24-h activity rhythms: a populationbased study. European Journal of Neurology, 22 (11), 1482-1487. doi: 10.1111/ene.12775
Scientific papers non-refereed Rauscher, C., Vervenne van Spandonk, R.M., Boltshauser, E. & Wolf, N.I. (2015). 4H-Syndrom - eine häufige Ursache für Hypomyelinisering. Neuropädiatrie in Klinik und Praxis, 14, 98-100. Scientific publications (books, monographs, book chapters, proceedings) Agorastos, A., Kellner, M., Baker, D.G. & Stiedl, O. (2015). Diminished vagal and/or increased sympathetic activity in Post-Traumatic Stress Disorder. pp. 1-15. In C.R. Martin, V.R. Preedy & V.B. Patel (Eds.), Comprehensive Guide to Post-Traumatic Stress Disorder (pp. 1-15). Switzerland: Springer International Publishing. Biancheri, R., Zara, F., Bruno, C., Gazzerro, E., Rossi, A., Knaap, M. & Minetti, C. (2015). Hypomyelination and Congenital Cataract. In R.A. Pagon, M.P. Adam & H.H. Ardinger (Eds.), GeneReviews® [internet]. Seattle (WA): University of Washington. Burke, S.M. & Bakker, J. (2015). The Role of Pubertal Hormones in the Development of Gender Identity: fMRI Studies. In Brain Crosstalk in Puberty and Adolescence (pp. 29-43).
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Knaap, M., Depienne, C., Sedel, F. & Abbink, T.E.M. (2015). CLCN2-Related Leukoencephalopathy. In R.A. Pagon, M.P. Adam & H.H. Ardinger (Eds.), GeneReviews® [internet]. Seattle (WA): University of Washington. Mahmutoglu, S. & Salomons, G.S. (2015). Creatine Deficiency Syndromes. In R.A. Pagon, M.P. Adam & H.H. Ardinger (Eds.), GeneReviews® [internet]. Seattle (WA): University of Washington. Ogren, S.O. & Stiedl, O. (2015). Passive avoidance. In I.P. Stolerman & L.H. Price (Eds.), Encyclopedia of Psychopharmacology (pp. 1220-1228). Berlin Heidelberg: Springer-Verlag. Vujacic, I. & Gunst, M.C.M. de (2015). Simultaneous perturbation gradient approximation based Metropolis adjusted Langevin Markov chain Monte Carlo for inference of ordinary differential equations. In S. Nagy (Ed.), Proceedings of the 19th European Young Statisticians Meeting (pp. 160-165). Prague. Wal, C.N. van der & Irrmischer, M. (2015). Measuring Emotion Regulation with Single Dry Electrode Brain Computer Interface. In Y. Guo, K. Friston, A. Faisal, S. Hill & H. Peng (Eds.), Brain Informatics and Health; Proceedings of the Brain Informatics and Health Conference 2015 (pp. 181-191). Switzerland: Springer International Publishing. Wal, C.N. van der & Irrmischer, M. (2015). Myndplay: Measuring Attention Regulation with Single Dry Electrode Brain Computer Interface. In Y. Guo, K. Friston, A. Faisal, S. Hill & H. Peng (Eds.), Brain Informatics and Health; Proceedings of the Brain Informatics and Health Conference 2015 (pp. 192-201). Switzerland: Springer International Publishing.
Professional publications König, T.E., Lee, J. van der, Schats, R. & Lambalk, C.B. (2015). Relatie FSHR-polymorfisme op positie 680 en doorgaande zwangerschap bij IVF/ICSI. Nederlands tijdschrift voor obstetrie & gynaecologie, 128 (3), 124-126. Scholten, I., Zijl, M. van, Custers, I.M., Brandes, M., Gianotten, J., Linden, P.J.Q. van der, Hompes, P.G.A., Veen, F. van der & Mol, B.W.J. (2015). Intra-uteriene inseminatie vs. afwachten bij paren met een slechte prognose op een spontane zwangerschap. Nederlands tijdschrift voor obstetrie & gynaecologie, 125 (3), 127-130.
Inaugural lecture Lambalk, C.B. (2015). Drempels meten en nemen (15-09-2015). Amsterdam: Vrije Universiteit.
Farewell lecture Blankenstein, M.A. (2015). Het bloed was weg (12-06-2015). Amsterdam: Vrije Universiteit.
Neurodegeneration Theses VU/VUmc PhD-student at VU (A) Adriaanse, S.M. (2015, April 07). Integrating functional and molecular imaging in Alzheimer's disease. VU University. Prom./coprom.: prof. dr. F. Barkhof, prof. dr. P. Scheltens, dr. B.N.M. van Berckel & dr. ing. A.M. Wink. Del Campo Milan, M. (2015, Juni 19). Novel Biochemical Signatures of Early Stages of Alzheimer's Disease. VU University. Prom./coprom.: prof. dr. M.A. Blankenstein, prof. dr. P. Scheltens, dr. ir. C.E. Teunissen & dr. C.R. Jimenez.
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Duits, F.H. (2015, April 01). Biomarkers for Alzheimer s disease: Current practice and new perspectives. VU University. Prom./coprom.: prof. dr. P. Scheltens, prof. dr. M.A. Blankenstein, prof. dr. W.M. van der Flier & dr. ir. C.E. Teunissen. Gerrits, N.J.H.M. (2015, September 11). Understanding cognitive heterogeneity in Parkinson's disease: An imaging approach. VU University. Prom./coprom.: prof. dr. D.J. Veltman, prof. dr. H.W. Berendse, dr. Y.D. van der Werf & dr. O.A. van den Heuvel. Moller, C. (2015, Mei 01). Imaging patterns of tissue destruction. Towards a better discrimination between types of dementia. VU University. Prom./coprom.: prof. dr. P. Scheltens, prof. dr. F. Barkhof, prof. dr. W.M. van der Flier & dr. ir. H. Vrenken. Smits, L.L. (2015, Maart 20). A cognitive perspective on clinical manifestations of Alzheimer s disease. VU University. Prom./coprom.: prof. dr. P. Scheltens, prof. dr. W.M. van der Flier & dr. Y.A.L. Pijnenburg. Verhaar, R. (2015, Oktober 19). Endoplasmic reticulum-stress and protein aggregation in Parkinson's disease: elucidating the contribution of tissue transglutaminase. VU University. Prom./coprom.: prof. dr. H.J. Groenewegen, dr. B. Drukarch & dr. M.M.M. Wilhelmus. Vriend, C. (2015, April 29). (Dis)Inhibition Imaging Neuropsychiatry in Parkinson's disease. VU University. Prom./coprom.: prof. dr. H.W. Berendse, prof. dr. J.H. Smit, dr. O.A. van den Heuvel & dr. Y.D. van der Werf.
Theses external PhD-student at VU (B) Kasius, K.M. (2015, November 05). Diagnostic considerations in carpal tunnel syndrome. VU University. Prom./coprom.: prof. dr. H.C. Weinstein, J. Meulstee & W.I.M. Verhagen. Moloney, E.B. (2015, Oktober 02). Semaphorin 3A in injury an disease: its role a the neuromuscular junction. VU Vrije Universiteit. Prom./coprom.: prof. dr. J. Verhaagen & Dr. F. de Winter.
Theses VU/VUmc PhD-student at other university (C) Doorn, K.J. (2015, Juni 30). Brain Region-Specific Microglial Phenotypes and Responses in Parkinson’s Disease. Universiteit van Amsterdam. Prom./coprom.: P.J. Lucassen, dr. A.M.W. van Dam & dr. B. Drukarch.
Theses external PhD-student at other university (D) Hamel, R. (2015, Juli 03). The course of mild cognitive impairment and the role of comorbidity. Universiteit Maastricht. Prom./coprom.: F.R.J. Verhey, I.H.G.B. Ramakers & dr. P.J. Visser.
Scientific papers refereed Abheiden, C.N.H., Doornik, R. van, Aukes, A.M., Flier, W.M. van der, Scheltens, P. & Groot, C.J.M. de (2015). Hypertensive Disorders of Pregnancy Appear Not to Be Associated with Alzheimer's Disease Later in Life. Dementia and Geriatric Cognitive Disorders EXTRA, 5 (3), 375-385. doi: 10.1159/000439043 Alafuzoff, I., Pikkarainen, M., Neumann, M., Arzberger, T., Al-Sarraj, S., Bodi, I., Bogdanovic, N., Bugiani, O., Ferrer, I., Gelpi, E., Gentleman, S., Giaccone, G., Graeber, M.B., Hortobagyi, T., Ince, P.G., Ironside, J.W., Kavantzas, N., King, A., Korkolopoulou, P., Kovacs, G.G., Meyronet, D., Monoranu, C., Nilsson, T., Parchi, P., Patsouris, E., Revesz, T., Roggendorf, W., Rozemuller, A.J.M., Seilhean, D., Streichenberger, N., Thal, D.R., Wharton, S.B. & Kretzschmar, H. (2015). Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium. Journal of Neural Transmission, 122 (7), 957-972. doi: 10.1007/s00702-014-1304-1 33
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Alders, D.J., Groeneveld, A.B.J., Binsl, T. W. & Beek, J.H.G.M. van (2015). Progressively heterogeneous mismatch of regional oxygen delivery to consumption during graded coronary stenosis in pig left ventricle. American Journal of Physiology. Heart and Circulatory Physiology, 309 (10), H1708H1719. doi: 10.1152/ajpheart.00657.2014 Amami, P., Dekker, I., Piacentini, S., Ferre, F., Romito, L.M., Franzini, A., Foncke, E.M.J. & Albanese, A. (2015). Impulse control behaviours in patients with Parkinson's disease after subthalamic deep brain stimulation: de novo cases and 3-year follow-up. Journal of Neurology, Neurosurgery and Psychiatry, 86 (5), 562-564. doi: 10.1136/jnnp-2013-307214 Andreasson, U., Perret-Liaudet, A., Doorn, L.J.C.V. van, Blennow, K., Chiasserini, D., Engelborghs, S., Fladby, T., Genc, S., Kruse, N., Kuipenj, H.B., Kulic, L., Lewczuk, P., Mollenhauer, B., Mroczko, B., Pametti, L., Vanmechelen, E., Verbeek, M.M., Winblad, B., Zetterberg, H., Koel-Simmelink, M.J.A. & Teunissen, C.E. (2015). A practical guide to immunoassay method validation. Frontiers in Neurology, 6, 179. doi: 10.3389/fneur.2015.00179 Barnes, J., Dickerson, B.C., Frost, C., Jiskoot, L.C., Wolk, D. & Flier, W.M. van der (2015). Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset. Alzheimers & Dementia, 11 (11), 1349-1357. doi: 10.1016/j.jalz.2014.12.007 Benedictus, M.R., Prins, N.D., Goos, J.D.C., Scheltens, P., Barkhof, F. & Flier, W.M. van der (2015). Microbleeds, Mortality, and Stroke in Alzheimer Disease The MISTRAL Study. JAMA Neurology, 72 (5), 539-545. doi: 10.1001/jamaneurol.2015.14 Benedictus, M.R., Hochart, A., Rossi, C., Boulouis, G., Henon, H., Flier, W.M. van der & Cordonnier, C. (2015). Prognostic Factors for Cognitive Decline After Intracerebral Hemorrhage. Stroke, 46 (10), 2773-2778. doi: 10.1161/STROKEAHA.115.010200 Benedictus, M.R., Harten, A.C. van, Leeuwis, A.E., Koene, T., Scheltens, P., Barkhof, F., Prins, N.D. & Flier, W.M. van der (2015). White Matter Hyperintensities Relate to Clinical Progression in Subjective Cognitive Decline. Stroke, 46 (9), 2661-2664. doi: 10.1161/STROKEAHA.115.009475 Bergen, AA, Kaing, S., Brink, J.B. ten, Gorgels, T.G. & Janssen, S.F. (2015). Gene expression and functional annotation of human choroid plexus epithelium failure in Alzheimer's disease. BMC Genomics, 16:956. doi: 10.1186/s12864-015-2159-z Bertens, D., Knol, D.L., Scheltens, P. & Visser, P.J. (2015). Temporal evolution of biomarkers and cognitive markers in the asymptomatic, MCI, and dementia stage of Alzheimer's disease. Alzheimers & Dementia, 11 (5), 511-522. doi: 10.1016/j.jalz.2014.05.1754 Bocchetta, M., Galluzzi, S., Kehoe, P.G., Aguera, E., Bernabei, R., Bullock, R., Ceccaldi, M., Dartigues, J.F., Mendonca, A. de, Didic, M., Eriksdotter, M., Felician, O., Frolich, L., Gertz, H.J., Hallikainen, M., Hasselbalch, S.G., Hausner, L., Heuser, I., Jessen, F., Jones, R.W., Kurz, A., Lawlor, B., Lleo, A., Martinez-Lage, P., Mecocci, P., Mehrabian, S., Monsch, A., Nobili, F., Nordberg, A., Rikkert, M.O., Orgogozo, J.M., Pasquier, F., Peters, O., Salmon, E., Sanchez-Castellano, C., Santana, I., Sarazin, M., Traykov, L., Tsolaki, M., Visser, P.J., Wallin, A.K., Wilcock, G., Wilkinson, D., Wolf, H, Yener, G., Zekry, D. & Frisoni, G. B. (2015). The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey. Alzheimers & Dementia, 11 (2), 195-206. doi: 10.1016/j.jalz.2014.06.006 Bour, L.J., Ackermans, L., Foncke, E.M.J., Cath, D., Linden, C. van der, Vandewalle, V.V. & Tijssen, M.A. (2015). Tic related local field potentials in the thalamus and the effect of deep brain stimulation in Tourette syndrome: Report of three cases. Clinical Neurophysiology, 126 (8), 1578-1588. doi: 10.1016/j.clinph.2014.10.217 Bron, E.E., Smits, M., Flier, W.M. van der, Vrenken, H., Barkhof, F., Scheltens, P., Papma, J.M., Steketee, R.M.E., Orellana, C.M., Meijboom, R., Pinto, M., Meireles, J.R., Garrett, C., Bastos-Leite, A.J., Abdulkadir, A., Ronneberger, O., Amoroso, N., Bellotti, R., Cardenas-Pena, D., Alvarez-Meza, A.M., Dolph, C.V., Iftekharuddin, K.M., Eskildsen, S.F., Coupe, P., Fonov, V.S., Franke, K., Gaser, C., Ledig, C., Guerrero, R., Tong, T., Gray, K.R., Moradi, E., Tohka, J., Routier, A., Durrleman, S., Sarica, A., Fatta, G. Di, Sensi, F., Chincarini, A., Smith, G.M., Stoyanov, Z.V., Sorensen, L., Nielsen, M., Tangaro, S., Inglese, P., Wachinger, C., Reuter, M., Swieten, J.C. van, Niessen, W.J. & Klein, S. (2015). Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge. NeuroImage, 111, 562-579. doi: 10.1016/j.neuroimage.2015.01.048
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Brueggen, K., Dyrba, M., Barkhof, F., Hausner, L., Filippi, M., Nestor, P.J., Hauenstein, K., Kloppel, S., Grothe, M.J., Kasper, E. & Teipel, S.J (2015). Basal Forebrain and Hippocampus as Predictors of Conversion to Alzheimer's Disease in Patients with Mild Cognitive Impairment - A Multicenter DTI and Volumetry Study. Journal of Alzheimer's Disease, 48 (1), 197-204. doi: 10.3233/JAD-150063 Bruggink, K.A., Kuiperij, H.B., Gloerich, J., Otte-Holler, I., Rozemuller, A.J.M., Claassen, J.A.H.R., Kusters, B. & Verbeek, M.M. (2015). Dickkopf-related protein 3 is a potential A beta-associated protein in Alzheimer's Disease. Journal of Neurochemistry, 134 (6), 1152-1162. doi: 10.1111/jnc.13216 Caroli, A., Prestia, A., Galluzzi, S., Ferrari, C., Flier, W.M. van der, Ossenkoppele, R., Berckel, B. van, Barkhof, F., Teunissen, C., Wall, A.E., Carter, S.F., Scholl, M., Choo, I.H., Grimmer, T., Redolfi, A., Nordberg, A., Scheltens, P., Drzezga, A. & Frisoni, G. B. (2015). Mild cognitive impairment with suspected nonamyloid pathology (SNAP) Prediction of progression. Neurology, 84 (5), 508-515. doi: 10.1212/WNL.0000000000001209 Chouliaras, L., Kenis, G., Visser, P.J., Scheltens, P., Tsolaki, M., Jones, R.W., Kehoe, P.G., Graff, C., Girtler, N.G., Wallin, A.K., Rikkert, M.O., Spiru, L., Elias-Sonnenschein, L.S., Ramakers, I.H.G.B., Pishva, E., Os, J van, Steinbusch, H.W.M., Verhey, F. R. J., Hove, D.L.A. van der & Rutten, B.P.F. (2015). DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts. Epigenomics, 7 (4), 533-537. doi: 10.2217/EPI.15.22 Coart, E., Barrado, L.G., Duits, F.H., Scheltens, P., Flier, W.M. van der, Teunissen, C.E., Vies, S.M. van der & Burzykowski, T. (2015). Correcting for the Absence of a Gold Standard Improves Diagnostic Accuracy of Biomarkers in Alzheimer's Disease. Journal of Alzheimer's Disease, 46 (4), 889-899. doi: 10.3233/JAD-142886 Del Campo Milan, M., Stargardt, A, Veerhuis, R., Reits, E. & Teunissen, C.E. (2015). Accumulation of BRI2BRICHOS ectodomain correlates with a decreased clearance of A beta by insulin degrading enzyme (IDE) in Alzheimer's disease. Neuroscience Letters, 589, 47-51. doi: 10.1016/j.neulet.2015.01.036 Del Campo Milan, M., Zuroff, L., Jimenez, C.R., Scheltens, P. & Teunissen, C.E. (2015). Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease? Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 1 (1), 75-80. doi: 10.1016/j.dadm.2014.11.008 Del Campo Milan, M., Jongbloed, W., Twaalfhoven, H.A.M., Veerhuis, R., Blankenstein, M.A. & Teunissen, C.E. (2015). Facilitating the validation of novel protein biomarkers for dementia: an optimal workflow for the development of sandwich immunoassays. Frontiers in Neurology, 6, 202. doi: 10.3389/fneur.2015.00202 Dellen, E. van, Waal, H. de, Flier, W.M. van der, Lemstra, A.W., Slooter, A.J.C., Smits, L.L., Straaten, E.C.W. van, Stam, C.J. & Scheltens, P. (2015). Loss of EEG Network Efficiency Is Related to Cognitive Impairment in Dementia With Lewy Bodies. Movement Disorders, 30 (13), 1785-1793. doi: 10.1002/mds.26309 Dijkstra, A.A., Ingrassia, A., Menezes, R.X., Kesteren, R.E. van, Rozemuller, A.J., Heutink, P. & Berg, W.D.J. van de (2015). Evidence for Immune Response, Axonal Dysfunction and Reduced Endocytosis in the Substantia Nigra in Early Stage Parkinson's Disease. PLoS One, 10 (6):e0128651. doi: 10.1371/journal.pone.0128651 Doorn, K.J., Breve, J.J.P., Drukarch, B., Boddeke, HW, Huitinga, I., Lucassen, P.J. & Dam, A.M. van (2015). Brain region-specific gene expression profiles in freshly isolated rat microglia. Frontiers in Cellular Neuroscience, 9, 84. doi: 10.3339/fncel.2015.00084 Douglas, C.M.W. & Scheltens, P. (2015). Rethinking biobanking and translational medicine in the Netherlands: how the research process stands to matter for patient care. European Journal of Human Genetics, 23 (6), 736-738. doi: 10.1038/ejhg.2014.186 Dubois, B., Padovani, A., Scheltens, P., Rossi, A. & Dell'Agnello, G. (2015). Timely Diagnosis for Alzheimer's Disease: A Literature Review on Benefits and Challenges. Journal of Alzheimer's Disease, 49 (3), 617-631. doi: 10.3233/JAD-150692 Duits, F.H., Prins, N.D., Lemstra, A.W., Pijnenburg, Y.A.L., Bouwman, F.H., Teunissen, C.E., Scheltens, P. & Flier, W.M. van der (2015). Diagnostic impact of CSF biomarkers for Alzheimer's disease in a tertiary memory clinic. Alzheimers & Dementia, 11 (5), 523-532. doi: 10.1016/j.jalz.2014.05.1753
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Duits, F.H., Hernandez-Guillamon, M., Montaner, J., Goos, J.D.C., Montanola, A., Wattjes, M.P., Barkhof, F., Scheltens, P., Teunissen, C.E. & Flier, W.M. van der (2015). Matrix Metalloproteinases in Alzheimer's Disease and Concurrent Cerebral Microbleeds. Journal of Alzheimer's Disease, 48 (3), 711-720. doi: 10.3233/JAD-143186 Javor-Duray, B.N., Vinck, M., Roest, M. van der, Mulder, A.B., Stam, C.J., Berendse, H.W. & Voorn, P. (2015). Early-onset cortico-cortical synchronization in the hemiparkinsonian rat model. Journal of Neurophysiology, 113 (3), 925-936. doi: 10.1152/jn.00690.2014 Dyrba, M., Barkhof, F., Fellgiebel, A., Filippi, M., Hausner, L., Hauenstein, K., Kirste, T. & Teipel, S.J (2015). Predicting Prodromal Alzheimer's Disease in Subjects with Mild Cognitive Impairment Using Machine Learning Classification of Multimodal Multicenter Diffusion-Tensor and Magnetic Resonance Imaging Data. Journal of Neuroimaging, 25 (5), 738-747. doi: 10.1111/jon.12214 Elbers, R.G., Verhoef, J., Wegen, E.E.H. van, Berendse, H.W. & Kwakkel, G. (2015). Interventions for fatigue in Parkinson's disease. Cochrane Database of Systematic Reviews, CD010925. doi: 10.1002/14651858.CD010925.pub2 Pijnenburg, Y.A.L., Verwey, N.A., Flier, W.M. van der, Scheltens, P. & Teunissen, C.E. (2015). Discriminative and prognostic potential of cerebrospinal fluid phosphoTau/tau ratio and neurofilaments for frontotemporal dementia subtypes. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 1 (4), 505-512. doi: 10.1016/j.dadm.2015.11.001 Engels, M.M.A., Stam, C.J., Flier, W.M. van der, Scheltens, P., Waal, H. de & Straaten, E.C.W. van (2015). Declining functional connectivity and changing hub locations in Alzheimer's disease: an EEG study. BMC Neurology, 15, 145. doi: 10.1186/s12883-015-0400-7 Exalto, L.G., Flier, W.M. van der, Boheemen, C.J.M. van, Kappelle, L.J., Vrenken, H., Teunissen, C., Koene, T., Scheltens, P. & Biessels, G.J. (2015). The metabolic syndrome in a memory clinic population: Relation with clinical profile and prognosis. Journal of the Neurological Sciences, 351 (1-2), 18-23. doi: 10.1016/j.jns.2015.02.004 Fagoe, N.D., Attwell, C.L., Kouwenhoven, D., Verhaagen, J. & Mason, M.R.J. (2015). Overexpression of ATF3 or the combination of ATF3, c-Jun, STAT3 and Smad1 promotes regeneration of the central axon branch of sensory neurons but without synergistic effects. Human Molecular Genetics, 24 (23), 6788-6800. doi: 10.1093/hmg/ddv383 Frederiksen, K.S., Verdelho, A., Madureira, S., Bazner, H., O'Brien, J. T., Fazekas, F., Scheltens, P., Schmidt, R., Wallin, A., Wahlund, L.O., Erkinjunttii, T., Poggesi, A., Pantoni, L., Inzitari, D. & Waldemar, G. (2015). Physical activity in the elderly is associated with improved executive function and processing speed: the LADIS Study. International Journal of Geriatric Psychiatry, 30 (7), 744-750. doi: 10.1002/gps.4220 Frisoni, G. B. & Visser, P.J. (2015). Biomarkers for Alzheimer's disease: a controversial topic. Lancet Neurology, 14 (8), 781-783. doi: 10.1016/S1474-4422(15)00150-7 Frisoni, G. B., Jack, C.R., Bocchetta, M., Bauer, C., Frederiksen, K.S., Liu, Y.W., Preboske, G., Swihart, T., Blair, M., Cavedo, E., Grothe, M.J., Lanfredi, M., Martinez, O., Nishikawa, M., Portegies, M., Stoub, T., Ward, C., Apostolova, L.G., Ganzola, R., Wolf, D., Barkhof, F., Bartzokis, G., deCarli, C., Csernansky, J.G., DeToledo-Morrell, L., Geerlings, M.I., Kaye, J., Killiany, R.J., Lehericy, S., Matsuda, H., O'Brien, J., Silbert, L.C., Scheltens, P., Soininen, H., Teipel, S., Waldemar, G., Fellgiebel, A., Barnes, J., Firbank, M., Gerritsen, L., Henneman, W., Malykhin, N., Pruessner, J.C., Wang, L., Watson, C., Wolf, H, deLeon, M., Pantel, J., Ferrari, C., Bosco, P., Pasqualetti, P., Duchesne, S., Duvernoy, H. & Boccardi, M. (2015). The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: Evidence of validity. Alzheimers & Dementia, 11 (2), 111125. doi: 10.1016/j.jalz.2014.05.1756 Gavai, A.K., Supandi, F.B., Hettling, H., Murell, P., Leunissen, J.A.M. & Beek, J.H. van (2015). Using bioconductor package BiGGR for metabolic flux estimation based on gene expression changes in brain. PLoS One, 10 (3):e0119016. doi: 10.1371/journal.pone.0119016 Gerrits, N.J.H.M., Werf, Y.D. van der, Verhoef, K.M.W., Veltman, D.J., Groenewegen, H.J., Berendse, H.W. & Heuvel, O.A. van den (2015). Compensatory fronto-parietal hyperactivation during set-shifting in unmedicated patients with Parkinson's disease. Neuropsychologia, 68, 107-116. doi: 10.1016/j.neuropsychologia.2014.12.022
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Gerrits, N.J.H.M., Heuvel, O.A. van den & Werf, Y.D. van der (2015). Decreased neural activity and neural connectivity while performing a set-shifting task after inhibiting repetitive transcranial magnetic stimulation on the left dorsal prefrontal cortex. BMC Neuroscience, 16, 45. doi: 10.1186/s12868015-0181-3 Ghielen, I., Heuvel, O.A. van den, Goede, C.J.T. de, Gier, M. de, Collette, E.H., Burgers-Bots, I.A.L., Rutten, S., Kwakkel, G., Vermunt, K., Vliet, B. van, Berendse, H.W. & Wegen, E.E.H. van (2015). BEWARE: Body awareness training in the treatment of wearing-off related anxiety in patients with Parkinson's disease: study protocol for a randomized controlled trial. Trials, 16, 283. doi: 10.1186/s13063-015-0804-0 Golla, S.V.V., Boellaard, R., Oikonen, V., Hoffmann, A., Berckel, B.N.M. van, Windhorst, A.D., Virta, J., Haaparanta-Solin, M., Luoto, P., Savisto, N., Solin, O., Valencia, R., Thiele, A., Eriksson, J., Schuit, R.C., Lammertsma, A.A. & Rinne, J.O. (2015). Quantification of [F-18]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients. Journal of Cerebral Blood Flow and Metabolism, 35 (5), 766-772. doi: 10.1038/jcbfm.2014.261 Grinberg, L.T., Jimenez, C.R. & Li, K.W. (2015). Neuroproteomics: Applications in Neuroscience and Neurology. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1854 (7), 703-704. doi: 10.1016/j.bbapap.2015.04.001 Hafkemeijer, A., Mรถller, C., Dopper, E.G.P., Jiskoot, L.C., Schouten, T.M., Swieten, J.C. van, Flier, W.M. van der, Vrenken, H., Pijnenburg, Y.A.L., Barkhof, F., Scheltens, P., Grond, J. van der & Rombouts, S.A.R.B. (2015). Resting state functional connectivity differences between behavioral variant frontotemporal dementia and Alzheimer's disease. Frontiers in Human Neuroscience, 9, 474. doi: 10.3389/fnhum.2015.00474 Hall, A., Munoz-Ruiz, M., Mattila, J., Koikkalainen, J., Tsolaki, M., Mecocci, P., Kloszewska, I., Vellas, B., Lovestone, S., Visser, P.J., Lotjonen, J. & Soininen, H. (2015). Generalizability of the Disease State Index Prediction Model for Identifying Patients Progressing from Mild Cognitive Impairment to Alzheimer's Disease. Journal of Alzheimer's Disease, 44 (1), 79-92. doi: 10.3233/JAD-140942 Hall, A., Mattila, J., Koikkalainen, J., Lojonen, J., Wolz, R., Scheltens, P., Frisoni, G., Tsolaki, M., Nobili, F., Freund-Levi, Y., Minthon, L., Froelich, L., Hampel, H., Visser, P.J. & Soininen, H. (2015). Predicting Progression from Cognitive Impairment to Alzheimer's Disease with the Disease State Index. Current Alzheimer Research, 12 (1), 69-79. doi: 10.2174/1567205012666141218123829 Hamel, R., Kohler, S., Sistermans, N., Koene, T., Pijnenburg, Y., Flier, W.M. van der, Scheltens, P., Aalten, P., Verhey, F., Visser, P.J. & Ramakers, I. (2015). The trajectory of cognitive decline in the predementia phase in memory clinic visitors: findings from the 4C-MCI study. Psychological Medicine, 45 (7), 1509-1519. doi: 10.1017/S0033291714002645 Harg, J.M. van der, Eggels, L., Ruigrok, S.R., Hoozemans, J.J., Fleur, S.E. la & Scheper, W. (2015). Neuroinflammation is not a Prerequisite for Diabetes-induced Tau Phosphorylation. Frontiers in Neuroscience, 9:432. doi: 10.3389/fnins.2015.00432 Harper, L., Barkhof, F., Fox, N.C. & Schott, J.M. (2015). Using visual rating to diagnose dementia: a critical evaluation of MRI atrophy scales. Journal of Neurology, Neurosurgery and Psychiatry, 86 (11), 1225-1233. doi: 10.1136/jnnp-2014-310090 Harten, A.C. van, Mulders, J, Scheltens, P., Flier, W.M. van der & Oudejans, C.B.M. (2015). Differential Expression of microRNA in Cerebrospinal Fluid as a Potential Novel Biomarker for Alzheimer's Disease. Journal of Alzheimer's Disease, 47 (1), 243-252. doi: 10.3233/JAD-140075 Harting, I., Boy, N., Heringer, J., Seitz, A., Bendszus, M., Pouwels, P.J.W. & Kolker, S. (2015). H-1-MRS in glutaric aciduria type 1: impact of biochemical phenotype and age on the cerebral accumulation of neurotoxic metabolites. Journal of Inherited Metabolic Disease, 38 (5), 829-838. doi: 10.1007/s10545-015-9826-8 Hooghiemstra, A.M., Eggermont, L.H.P., Scheltens, P., Flier, W.M. van der & Scherder, E.J.A. (2015). The Rest-Activity Rhythm and Physical Activity in Early-Onset Dementia. Alzheimer Disease and Associated Disorders, 29 (1), 45-49. doi: 10.1097/WAD.0000000000000037 Hoyng, S.A., Winter, F. de, Gnavi, S., Egmond, L. van, Attwell, C.L., Tannemaat, M.R., Verhaagen, J. & Malessy, M.J.A. (2015). Gene delivery to rat and human Schwann cells and nerve segments: a comparison of AAV 1-9 and lentiviral vectors. Gene Therapy, 22 (10), 767-780. doi: 10.1038/gt.2015.47
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Jager, M., Drukarch, B., Hofstee, M., Breve, J., Jongenelen, C.A.M., Bol, J.G.J.M. & Wilhelmus, M.M.M. (2015). Tissue transglutaminase-catalysed cross-linking induces Apolipoprotein E multimers inhibiting Apolipoprotein E's protective effects towards amyloid-beta-induced toxicity. Journal of Neurochemistry, 134 (6), 1116-1128. doi: 10.1111/jnc.13203 Jahn, N., Lamberts, R.R., Busch, C.J., Voelker, M.T., Busch, T., Koel-Simmelink, M.J.A., Teunissen, C.E., Oswald, D.D., Loer, S.A., Kaisers, U.X. & Weimann, J. (2015). Inhaled carbon monoxide protects time-dependently from loss of hypoxic pulmonary vasoconstriction in endotoxemic mice. Respiration Research, 16, 119. doi: 10.1186/s12931-015-0274-7 Jansen, I.E., Bras, J.M., Lesage, S., Schulte, C., Gibbs, J.R., Nalls, M.A., Brice, A., Wood, N.W., Morris, H., Hardy, J.A., Singleton, A.B., Gasser, T., Heutink, P. & Sharma, M. (2015). CHCHD2 and Parkinson's disease. Lancet Neurology, 14 (7), 678-679. doi: 10.1016/S1474-4422(15)00094-0 Jansen, W.J., Ossenkoppele, R. & Visser, P.J. (2015). Amyloid Pathology, Cognitive Impairment, and Alzheimer Disease Risk Reply. JAMA, 314 (11), 1177-1178. doi: 10.1001/jama.2015.9719 Jansen, W.J., Ossenkoppele, R., Knol, D.L., Tijms, B.M., Scheltens, P., Verhey, F. R. J. & Visser, P.J. (2015). Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia A Meta-analysis. JAMA, 313 (19), 1924-1938. doi: 10.1001/jama.2015.4668 Janssen, S.F., Jansonius, N.M., Bouwman, F., Verbraak, F.D. & Bergen, AA (2015). Systematic review of the association between Alzheimer's disease and chronic glaucoma. Clinical ophthalmology, 9, 783784. doi: 10.2147/OPTH.S83197 Jochemsen, H.M., Flier, W.M. van der, Ashby, E.L., Teunissen, C.E., Jones, R.E., Wattjes, M.P., Scheltens, P., Geerlings, M.I., Kehoe, P.G. & Muller, M. (2015). Angiotensin-Converting Enzyme in Cerebrospinal Fluid and Risk of Brain Atrophy. Journal of Alzheimer's Disease, 44 (1), 153-162. doi: 10.3233/JAD-131496 Jochemsen, H.M., Muller, M., Bots, M.L., Scheltens, P., Vincken, K.L., Mali, W.P.T.M., Graaf, Y. van der & Geerlings, M.I. (2015). Arterial stiffness and progression of structural brain changes The SMARTMR study. Neurology, 84 (5), 448-455. doi: 10.1212/WNL.0000000000001201 Jongbloed, W., Bruggink, K.A., Kester, M.I., Visser, P.J., Scheltens, P., Blankenstein, M.A., Verbeek, M.M., Teunissen, C.E. & Veerhuis, R. (2015). Amyloid-beta Oligomers Relate to Cognitive Decline in Alzheimer's Disease. Journal of Alzheimer's Disease, 45 (1), 35-43. doi: 10.3233/JAD-142136 Jongbloed, W., Dijk, K.D. van, Mulder, S.D., Berg, W.D.J. van de, Blankenstein, M.A., Flier, W.M. van der & Veerhuis, R. (2015). Clusterin Levels in Plasma Predict Cognitive Decline and Progression to Alzheimer's Disease. Journal of Alzheimer's Disease, 46 (4), 1103-1110. doi: 10.3233/JAD-150036 Jonker, F.A., Jonker, C., Scheltens, P. & Scherder, E.J.A. (2015). The role of the orbitofrontal cortex in cognition and behavior. Reviews in the Neurosciences, 26 (1), 1-11. doi: 10.1515/revneuro-20140043 Kester, M.I., Teunissen, C.E., Sutphen, C., Herries, E.M., Ladenson, J.H., Xiong, C.J., Scheltens, P., Flier, W.M. van der, Morris, J.C., Holtzman, D.M. & Fagan, A.M. (2015). Cerebrospinal fluid VILIP-1 and YKL-40, candidate biomarkers to diagnose, predict and monitor Alzheimer's disease in a memory clinic cohort. Alzheimer's Research & Therapy, 7, 59. doi: 10.1186/s13195-015-0142-1 Kester, M.I., Teunissen, C.E., Crimmins, D.L., Herries, E.M., Ladenson, J.H., Scheltens, P., Flier, W.M. van der, Morris, J.C., Holtzman, D.M. & Fagan, A.M. (2015). Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease. JAMA Neurology, 72 (11), 12751280. doi: 10.1001/jamaneurol.2015.1867 Koster, N., Knol, D.L., Uitdehaag, B.M.J., Scheltens, P. & Sikkes, S.A.M. (2015). The sensitivity to change over time of the Amsterdam IADL Questionnaire(C). Alzheimers & Dementia, 11 (10), 1231-1240. doi: 10.1016/j.jalz.2014.10.006 Krudop, W.A., Bosman, S., Geurts, J.J.G., Sikkes, S.A.M., Verwey, N.A., Stek, M.L., Scheltens, P., Rozemuller, A.J.M. & Pijnenburg, Y.A.L. (2015). Clinico-Pathological Correlations of the Frontal Lobe Syndrome: Results of a Large Brain Bank Study. Dementia and Geriatric Cognitive Disorders, 40 (3-4), 121-129. doi: 10.1159/000430460 Krudop, W.A. & Pijnenburg, Y.A.L. (2015). Historical Evolution of the Frontal Lobe Syndrome. Psychopathology, 48 (4), 222-229. doi: 10.1159/000381986 Krudop, W.A., Kerssens, C.J., Dols, A., Prins, N.D., Moller, C., Schouws, S., Flier, W.M. van der, Scheltens, P., Sikkes, S.A.M., Stek, M.L. & Pijnenburg, Y.A.L. (2015). Identifying bvFTD Within the Wide
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Spectrum of Late Onset Frontal Lobe Syndrome: A Clinical Approach. American Journal of Geriatric Psychiatry, 23 (10), 1056-1066. doi: 10.1016/j.jagp.2015.04.002 Kvartsberg, H., Duits, F.H., Ingelsson, M., Andreasen, N., Ohrfelt, A., Andersson, K., Brinkmalm, G., Lannfelt, L., Minthon, L., Hansson, O., Andreasson, U., Teunissen, C.E., Scheltens, P., Flier, W.M. van der, Zetterberg, H., Portelius, E. & Blennow, K. (2015). Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease. Alzheimers & Dementia, 11 (10), 1180-1190. doi: 10.1016/j.jalz.2014.10.009 Lee, S.J. van der, Holstege, H., Wong, T.H., Jakobsdottir, J., Bis, J.C., Chouraki, V., Rooij, J.G.J. van, Grove, M.L., Smith, A.V., Amin, N., Choi, S.H., Beiser, A.S., Garcia, M.E., Ijcken, W.F.J. van, Pijnenburg, Y.A.L., Louwersheimer, E., Brouwer, R.W.W., Hout, M.C.G.N. van den, Oole, E., Eirkisdottir, G., Levy, D., Rotter, J.I., Emilsson, V., O'Donnell, C.J., Aspelund, T., Uitterlinden, A. G., Launer, L.J., Hofman, A., Boerwinkle, E., Psaty, B.M., DeStefano, A.L., Scheltens, P., Seshadri, S., Swieten, J.C. van, Gudnason, V., Flier, W.M. van der, Ikram, M.A. & Duijn, C.M. van (2015). PLD3 variants in population studies. Nature, 520 (7545), E2-E3. doi: 10.1038/nature14038 Leeuwen, L.A.G. van & Hoozemans, J.J.M. (2015). Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer's disease. Acta Neuropathologica, 129 (4), 511-525. doi: 10.1007/s00401-015-1382-7 Lerche, S., Liepelt-Scarfone, I., Alves, G., Barone, P., Behnke, S., Ben-Shlomo, Y., Berendse, H.W., Burn, D., Dodel, R., Grosset, D., Heinzel, S., Hu, M., Kasten, M., Kruger, R., Maetzler, W., Moccia, M., Mollenhauer, B., Oertel, W., Roeben, B., Sunkel, U., Walter, U., Wirdefeldt, K. & Berg, D. (2015). Methods in Neuroepidemiology Characterization of European Longitudinal Cohort Studies in Parkinson's Disease - Report of the JPND Working Group BioLoC-PD. Neuroepidemiology, 45 (4), 282-297. doi: 10.1159/000439221 Limpens, J.H.W., Damsteegt, R., Broekhoven, M.H., Voorn, P. & Vanderschuren, L.J.M.J. (2015). Pharmacological inactivation of the prelimbic cortex emulates compulsive reward seeking in rats. Brain Research, 1628, 210-218. doi: 10.1016/j.brainres.2014.10.045 Lleo, A., Cavedo, E., Parnetti, L., Vanderstichele, H., Herukka, S.K., Andreasen, N., Ghidoni, R., Lewczuk, P., Jeromin, A., Winblad, B., Tsolaki, M., Mroczko, B., Visser, P.J., Santana, I., Svenningsson, P., Blennow, K., Aarsland, D., Molinuevo, J.L., Zetterberg, H. & Mollenhauer, B. (2015). Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases. Nature Reviews Neurology, 11 (1), 41-55. doi: 10.1038/nrneurol.2014.232 Louwersheimer, E., Ramirez, A., Cruchaga, C., Becker, T., Kornhuber, J., Peters, O., Heilmann, S., Wiltfang, J., Jessen, F., Visser, P.J., Scheltens, P., Pijnenburg, Y.A.L., Teunissen, C.E., Barkhof, F., Swieten, J.C. van, Holstege, H. & Flier, W.M. van der (2015). The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease. Neurobiology of Aging, 36 (3), 1605-1620. doi: 10.1016/j.neurobiolaging.2014.12.007 Luik, A.I., Zuurbier, L.A., Hofman, A., Someren, E.J.W. van, Ikram, M.A. & Tiemeier, H. (2015). Associations of the 24-h activity rhythm and sleep with cognition: a population-based study of middle-aged and elderly persons. Sleep Medicine, 16 (7), 850-855. doi: 10.1016/j.sleep.2015.03.012 Maat, P., Beukelaar, J.W. de, Jansen, C., Schuur, M., Duijn, C.M. van, Coevorden, M.H. van, Graaff, E. de, Titulaer, E., Rozemuller, A.J.M. & Smitt, P. Sillevis (2015). Pathologically confirmed autoimmune encephalitis in suspected Creutzfeldt-Jakob disease. Neurology neuroimmunology & neuroinflammation, 2 (6), e178. doi: 10.1212/NXI.0000000000000178 Rhodius-Meester, H.F.M., Koikkalainen, J., Mattila, J., Teunissen, C.E., Barkhof, F., Lemstra, A.W., Scheltens, P., Lotjonen, J. & Flier, W.M. van der (2015). Integrating Biomarkers for Underlying Alzheimer’s Disease in Mild Cognitive Impairment in Daily Practice: Comparison of a Clinical Decision Support System with Individual Biomarkers. Journal of Alzheimer's Disease, 50 (1), 261270. doi: 10.3233/JAD-150548 Mierlo, T.J.M. van, Chung, C., Foncke, E.M., Berendse, H.W. & Heuvel, O.A. van den (2015). Depressive Symptoms in Parkinson's Disease Are Related to Decreased Hippocampus and Amygdala Volume. Movement Disorders, 30 (2), 245-252. doi: 10.1002/mds.26112 Mohedano-Moriano, A., Munoz-Lopez, M., Sanz-Arigita, E.J., Pro-Sistiaga, P., Martinez-Marcos, A., Legidos-Garcia, M.E., Insausti, A.M., Cebada-Sanchez, S., Arroyo-Jimenez, M.D., Marcos, P., Artacho-Perula, E. & Insausti, R. (2015). Prefrontal cortex afferents to the anterior temporal lobe in
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the Macaca fascicularis monkey. Journal of Comparative Neurology, 523 (17), 2570-2598. doi: 10.1002/cne.23805 Mรถller, C., Hafkemeijer, A., Pijnenburg, Y.A., Rombouts, S.A.R.B., Grond, J. van der, Dopper, E.G.P., Swieten, J.C. van, Versteeg, A., Pouwels, P.J.W., Barkhof, F., Scheltens, P., Vrenken, H. & Flier, W.M. van der (2015). Joint assessment of white matter integrity, cortical and subcortical atrophy to distinguish AD from behavioral variant FTD: A two-center study. NeuroImage: Clinical, 9, 418429. doi: 10.1016/j.nicl.2015.08.022 Mรถller, C., Dieleman, N., Flier, W.M. van der, Versteeg, A., Pijnenburg, Y., Scheltens, P., Barkhof, F. & Vrenken, H. (2015). More Atrophy of Deep Gray Matter Structures in Frontotemporal Dementia Compared to Alzheimer's Disease. Journal of Alzheimer's Disease, 44 (2), 635-647. doi: 10.3233/JAD-141230 Morbelli, S., Brugnolo, A., Bossert, I., Buschiazzo, A., Frisoni, G. B., Galluzzi, S., Berckel, B.N.M. van, Ossenkoppele, R., Perneczkyf, R., Drzezga, A., Didic, M., Guedj, E., Sambuceti, G., Bottoni, G., Arnaldi, D., Picco, A., Carli, F. De, Pagani, M. & Nobili, F. (2015). Visual Versus Semi-Quantitative Analysis of F-18-FDG-PET in Amnestic MCI: An European Alzheimer's Disease Consortium (EADC) Project. Journal of Alzheimer's Disease, 44 (3), 815-826. doi: 10.3233/JAD-142229 Morley, J.E., Morris, J.C., Berg-Weger, M., Borson, S., Carpenter, B.D., Campo, N. del, Dubois, B., Fargo, K., Fitten, L.J., Flaherty, J.H., Ganguli, M., Grossberg, G.T., Malmstrom, T.K., Petersen, R.D., Rodriguez, C., Saykin, A.J., Scheltens, P., Tangalos, E.G., Verghese, J., Wilcock, G., Winblad, B., Woo, J. & Vellas, B. (2015). Brain Health: The Importance of Recognizing Cognitive Impairment: An IAGG Consensus Conference. Journal of the American Medical Directors Association, 16 (9), 731-739. doi: 10.1016/j.jamda.2015.06.017 Nalls, M.A., Bras, J., Hernandez, D.G., Keller, M.F., Majounie, E., Renton, A.E., Saad, M., Jansen, I.E., Guerreiro, R., Lubbe, S., Plagnol, V., Gibbs, J.R., Schulte, C., Pankratz, N., Sutherland, M., Bertram, L., Lill, C.M., DeStefano, A.L., Faroud, T., Eriksson, N., Tung, J.Y., Edsall, C., Nichols, N., Brooks, J., Arepalli, S., Pliner, H., Letson, C., Heutink, P., Martinez, M., Gasser, T., Traynor, B.J., Wood, N., Hardy, J. & Singleton, A.B. (2015). NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases. Neurobiology of Aging, 36 (3), 1605.e7-1605.e12. doi: 10.1016/j.neurobiolaging.2014.07.028 Nichols, N., Bras, J.M., Hernandez, D.G., Jansen, I.E., Lesage, S., Lubbe, S. & Singleton, A.B. (2015). EIF4G1 mutations do not cause Parkinson's disease. Neurobiology of Aging, 36 (8), 2444. doi: 10.1016/j.neurobiolaging.2015.04.017 Ossenkoppele, R., Cohn-Sheehy, B.I., Joie, R. La, Vogel, J.W., Moller, C., Lehmann, M., Berckel, B.N.M. van, Seeley, W.W., Pijnenburg, Y.A., Gorno-Tempini, M.L., Kramer, J.H., Barkhof, F., Rosen, H.J., Flier, W.M. van der, Jagust, W.J., Miller, B.L., Scheltens, P. & Rabinovici, G.D. (2015). Atrophy patterns in early clinical stages across distinct phenotypes of Alzheimer's disease. Human Brain Mapping, 36 (11), 4421-4437. doi: 10.1002/hbm.22927 Ossenkoppele, R., Mattsson, N., Teunissen, C.E., Barkhof, F., Pijnenburg, Y., Scheltens, P., Flier, W.M. van der & Rabinovici, G.D. (2015). Cerebrospinal fluid biomarkers and cerebral atrophy in distinct clinical variants of probable Alzheimer's disease. Neurobiology of Aging, 36 (8), 2340-2347. doi: 10.1016/j.neurobiolaging.2015.04.011 Ossenkoppele, R., Jansen, W.J., Rabinovici, G.D., Knol, D.L., Flier, W.M. van der, Berckel, B.N.M. van, Scheltens, P. & Visser, P.J. (2015). Prevalence of Amyloid PET Positivity in Dementia Syndromes A Meta-analysis. JAMA, 313 (19), 1939-1949. doi: 10.1001/jama.2015.4669 Ossenkoppele, R., Schonhaut, D.R., Baker, S.L., O'Neil, J.P., Janabi, M., Ghosh, P.M., Santos, M., Miller, Z.A., Bettcher, B.M., Gorno-Tempini, M.L., Miller, B.L., Jagust, W.J. & Rabinovici, G.D. (2015). Tau, Amyloid, and Hypometabolism in a Patient with Posterior Cortical Atrophy. Annals of Neurology, 77 (2), 338-342. doi: 10.1002/ana.24321 Ossenkoppele, R., Pijnenburg, Y.A.L., Perry, D.C., Cohn-Sheehy, B.I., Scheltens, N.M.E., Vogel, J.W., Kramer, J.H., Vlies, A.E. van der, Joie, R. La, Rosen, H.J., Flier, W.M. van der, Grinberg, L.T., Rozemuller, A.J.M., Huang, E.J., Berckel, B.N.M. van, Miller, B.L., Barkhof, F., Jagust, W.J., Scheltens, P., Seeley, W.W. & Rabinovici, G.D. (2015). The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features. Brain, 138, 2732-2749. doi: 10.1093/brain/awv191
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Pagani, M., Carli, F. De, Morbelli, S., Oberg, J., Chincarini, A., Frisoni, G. B., Galluzzi, S., Perneczky, R., Drzezga, A., Berckel, B.N.M. van, Ossenkoppele, R., Didic, M., Guedj, E., Brugnolo, A., Picco, A., Arnaldi, D., Ferrara, M., Buschiazzo, A., Sambuceti, G. & Nobili, F. (2015). Volume of interest-based [18F]fluorodeoxyglucose PET discriminates MCI converting to Alzheimer's disease from healthy controls. A European Alzheimer's Disease Consortium (EADC) study. NeuroImage: Clinical, 7, 34-42. doi: 10.1016/j.nicl.2014.11.007 Petzold, A.F.S. (2015). Glial fibrillary acidic protein is a body fluid biomarker for glial pathology in human disease. Brain Research, 1600, 17-31. doi: 10.1016/j.brainres.2014.12.027 Prestia, A., Caroli, A., Wade, S.K., Flier, W.M. van der, Ossenkoppele, R., Berckel, B. van, Barkhof, F., Teunissen, C.E., Wall, A., Carter, S.F., Scholl, M., Choo, I.H., Nordberg, A., Scheltens, P. & Frisoni, G. B. (2015). Prediction of AD dementia by biomarkers following the NIA-AA and IWG diagnostic criteria in MCI patients from three European memory clinics. Alzheimers & Dementia, 11 (10), 1191-1201. doi: 10.1016/j.jalz.2014.12.001 Prins, N.D. & Scheltens, P. (2015). White matter hyperintensities, cognitive impairment and dementia: an update. Nature Reviews Neurology, 11 (3), 157-165. doi: 10.1038/nrneurol.2015.10 Rabin, L.A., Smart, C.M., Crane, P.K., Amariglio, R.E., Berman, L.M., Boada, M., Buckley, R.F., Chetelat, G., Dubois, B., Ellis, K.A., Gifford, K.A., Jefferson, A.L., Jessen, F., Katz, M.J., Lipton, R.B., Luck, T., Maruff, P., Mielke, M.M., Molinuevo, J.L., Naeem, F., Perrotin, A., Petersen, R.C., Rami, L., Reisberg, B., Rentz, D.M., Riedel-Heller, S.G., Risacher, S.L., Rodriguez, O., Sachdev, P.S., Saykin, A.J., Slavin, M.J., Snitz, B.E., Sperling, R.A., Tandetnik, C., Flier, W.M. van der, Wagner, M., Wolfsgruber, S. & Sikkes, S.A.M. (2015). Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies. Journal of Alzheimer's Disease, 48, S63-S86. doi: 10.3233/JAD-150154 Ramakers, I.H.G.B., Honings, S.T.H., Ponds, R.W., Aalten, P., Kohler, S., Verhey, F. R. J. & Visser, P.J. (2015). The Effect of Psychological Distress and Personality Traits on Cognitive Performances and the Risk of Dementia in Patients with Mild Cognitive Impairment. Journal of Alzheimer's Disease, 46 (3), 805-812. doi: 10.3233/JAD-142493 Reijs, B.L.R., Teunissen, C.E., Goncharenko, N., Betsou, F., Blennow, K., Baldeiras, I., Brosseron, F., Cavedo, E., Fladby, T., Froelich, L., Gabryelewicz, T., Gurvit, H., Kapaki, E., Koson, P., Kulic, L., Lehmann, S., Lewczuk, P., Lleo, A., Maetzler, W., Mendonca, A. de, Miller, A.M., Molinuevo, J.L., Mollenhauer, B., Parnetti, L., Rot, U., Schneider, A., Simonsen, A.H., Tagliavini, F., Tsolaki, M., Verbeek, M.M., Verhey, F. R. J., Zboch, M., Winblad, B., Scheltens, P., Zetterberg, H. & Visser, P.J. (2015). The central biobank and virtual biobank of BiOMarKaPD: a resource for studies on neurodegenerative diseases. Frontiers in Neurology, 6, 216. doi: 10.3389/fneur.2015.00216 Riaz, M., Raz, Y., Moloney, E.B., Putten, M., Krom, Y.D., Maarel, S.M. van der, Verhaagen, J. & Raz, V. (2015). Differential myofiber-type transduction preference of adeno-associated virus serotypes 6 and 9. Skeletal Muscle, 5, 37-37. doi: 10.1186/s13395-015-0064-4 Richiardi, J., Monsch, A.U., Haas, T., Barkhof, F., Ville, D. Van de, Radu, E.W., Kressig, R.W. & Haller, S. (2015). Altered cerebrovascular reactivity velocity in mild cognitive impairment and Alzheimer's disease. Neurobiology of Aging, 36 (1), 33-41. doi: 10.1016/j.neurobiolaging.2014.07.020 Rijpma, A., Meulenbroek, O., Hees, A.M.J. van, Sijben, J.W.C., Vellas, B., Shah, R.C., Bennett, D.A., Scheltens, P. & Rikkert, M.G.M.O. (2015). Effects of Souvenaid on plasma micronutrient levels and fatty acid profiles in mild and mild-to-moderate Alzheimer's disease. Alzheimer's Research & Therapy, 7, 51. doi: 10.1186/s13195-015-0134-1 Rikkert, M.G.M.O., Verhey, F. R., Blesa, R., Arnim, C.A.F. von, Bongers, A., Harrison, J., Sijben, J., Scarpini, E., Vandewoude, M.F.J., Vellas, B., Witkamp, R., Kamphuis, P.J.G.H. & Scheltens, P. (2015). Tolerability and Safety of Souvenaid in Patients with Mild Alzheimer's Disease: Results of MultiCenter, 24-Week, Open-Label Extension Study. Journal of Alzheimer's Disease, 44 (2), 471-480. doi: 10.3233/JAD-141305 Rooden, S. van, Doan, N.T., Versluis, M.J., Goos, J.D.C., Webb, A.G., Oleksik, A.M., Flier, W.M. van der, Scheltens, P., Barkhof, F., Weverlinge-Rynsburger, A.W.E., Blauw, G. J., Reiber, J.H.C., Buchem, M.A. van, Milles, J. & Grond, J. van der (2015). 7T T-2*-weighted magnetic resonance imaging reveals cortical phase differences between early- and late-onset Alzheimer's disease. Neurobiology of Aging, 36 (1), 20-26. doi: 10.1016/j.neurobiolaging.2014.07.006
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Rosenberger, A.F.N., Hilhorst, R., Coart, E., Barrado, L. Garcia, Naji, F., Rozemuller, A.J.M., Flier, W.M. van der, Scheltens, P., Hoozemans, J.J.M. & Vies, S.M. van der (2015). Protein Kinase Activity Decreases with Higher Braak Stages of Alzheimer's Disease Pathology. Journal of Alzheimer's Disease, 49 (4), 927-943. doi: 10.3233/JAD-150429 Rutten, S., Ghielen, I., Vriend, C., Hoogendoorn, A.W., Berendse, H.W., Leentjens, A.F.G., Werf, Y.D. van der, Smit, J.H. & Heuvel, O.A. van den (2015). Anxiety in Parkinson's disease: Symptom dimensions and overlap with depression and autonomic failure. Parkinsonism and Related Disorders, 21 (3), 189-193. doi: 10.1016/j.parkreldis.2014.11.019 Scheper, W. & Hoozemans, J.J. (2015). The unfolded protein response in neurodegenerative diseases: a neuropathological perspective. Acta Neuropathologica Communinications, 130 (3), 315-331. doi: 10.1007/s00401-015-1462-8 Schmidt, R., Hofer, E., Bouwman, F.H., Buerger, K, Cordonnier, C., Fladby, T., Galimberti, D., Georges, J., Heneka, M.T., Hort, J., Laczo, J., Molinuevo, J.L., O'Brien, J. T., Religa, D., Scheltens, P., Schott, J.M. & Sorbi, S. (2015). EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease. European Journal of Neurology, 22 (6), 889-898. doi: 10.1111/ene.12707 Smits, L.L., Pijnenburg, Y.A.L., Vlies, A.E. van der, Koedam, E.L.G.E., Bouwman, F.H., Reuling, I.E.W., Scheltens, P. & Flier, W.M. van der (2015). Early onset APOE E4-negative Alzheimer's disease patients show faster cognitive decline on non-memory domains. European Neuropsychopharmacology, 25 (7), 1010-1017. doi: 10.1016/j.euroneuro.2015.03.014 Smits, L.L., Harten, A.C. van, Pijnenburg, Y.A.L., Koedam, E.L.G.E., Bouwman, F.H., Sistermans, N., Reuling, I.E.W., Prins, N.D., Lemstra, A.W., Scheltens, P. & Flier, W.M. van der (2015). Trajectories of cognitive decline in different types of dementia. Psychological Medicine, 45 (5), 1051-1059. doi: 10.1017/S0033291714002153 Steenoven, I. van, Aarsland, D. & Weintraub, D. (2015). Reply to letter to the editor "Independent application of MoCA/MMSE conversion' by Armstrong et al. Movement Disorders, 30 (12), 17111711. doi: 10.1002/mds.26367 Straaten, E.C.W. van, Haan, J. den, Waal, H. de, Flier, W.M. van der, Barkhof, F., Prins, N.D. & Stam, C.J. (2015). Disturbed phase relations in white matter hyperintensity based vascular dementia: An EEG directed connectivity study. Clinical Neurophysiology, 126 (3), 497-504. doi: 10.1016/j.clinph.2014.05.018 Tang, E.Y.H., Harrison, S.L., Errington, L., Gordon, M.F., Visser, P.J., Novak, G., Dufouil, C., Brayne, C., Robinson, L., Launer, L.J. & Stephan, B.C.M. (2015). Current Developments in Dementia Risk Prediction Modelling: An Updated Systematic Review. PLoS One, 10 (9), 1. doi: 10.1371/journal.pone.0136181 Teunissen, C.E., Flier, W.M. van der, Scheltens, P., Duits, A., Wijnstok, N.J, Nijpels, G., Dekker, J.M., Blankenstein, M.A. & Heijboer, A.C. (2015). Serum Leptin is not Altered nor Related to Cognitive Decline in Alzheimer's Disease. Journal of Alzheimer's Disease, 44 (3), 809-813. doi: 10.3233/JAD141503 Tijms, B.M., Sprooten, E., Job, D., Johnstone, E.C., Owens, D.G.C., Willshaw, D., Series, P. & Lawrie, S.M. (2015). Grey matter networks in people at increased familial risk for schizophrenia. Schizophrenia Research, 168 (1-2), 1-8. doi: 10.1016/j.schres.2015.08.025 Tolboom, N., Berendse, H.W., Leysen, J.E., Yaqub, M., Berckel, B.N.M. van, Schuit, R.C., Ponsen, M.M., Bakker, E., Hoetjes, N.J., Windhorst, A.D., Carlsson, M.L., Lammertsma, A.A. & Carlsson, A. (2015). The Dopamine Stabilizer (-)-OSU6162 Occupies a Subpopulation of Striatal Dopamine D2/D3 Receptors: An [C-11] Raclopride PET Study in Healthy Human Subjects. Neuropsychopharmacology, 40 (2), 472-479. doi: 10.1038/npp.2014.195 Toledo, J.B., Zetterberg, H., Harten, A.C. van, Glodzik, L., Martinez-Lage, P., Bocchio-Chiavetto, L., Rami, L., Hansson, O., Sperling, R., Engelborghs, S., Osorio, R.S., Vanderstichele, H., Vandijck, M., Hampel, H., Teipl, S., Moghekar, A., Albert, M., Hu, W.T., Argiles, J.A.M., Gorostidi, A., Teunissen, C.E., Deyn, P.P. de, Hyman, B.T., Molinuevo, J.L., Frisoni, G. B., Linazasoro, G., Leon, M.J. de, Flier, W.M. van der, Scheltens, P., Blennow, K., Shaw, L.M. & Trojanowski, J.Q. (2015). Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain, 138, 2701-2715. doi: 10.1093/brain/awv199
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Trujillo, J.P., Gerrits, N.J.H.M., Vriend, C., Berendse, H.W., Heuvel, O.A. van den & Werf, Y.D. van der (2015). Impaired planning in Parkinson's disease is reflected by reduced brain activation and connectivity. Human Brain Mapping, 36 (9), 3703-3715. doi: 10.1002/hbm.22873 Trujillo, J.P., Gerrits, N.J.H.M., Veltman, D.J., Berendse, H.W., Werf, Y.D. van der & Heuvel, O.A. van den (2015). Reduced Neural Connectivity But Increased Task-Related Activity During Working Memory in De Novo Parkinson Patients. Human Brain Mapping, 36 (4), 1554-1566. doi: 10.1002/hbm.22723 Vaikath, N.N., Majbour, N.K., Paleologou, K.E., Ardah, M.T., Dam, E. van, Berg, W.D.J. van de, Forrest, S.L., Parkkinen, L., Gai, W.P., Hattori, N., Takanashi, M., Lee, S.J. van der, Mann, D.M.A., Imai, Y., Halliday, G.M., Li, J.Y. & El-Agnaf, O.M.A. (2015). Generation and characterization of novel conformation-specific monoclonal antibodies for alpha-synuclein pathology. Neurobiology of Disease, 79, 81-99. doi: 10.1016/j.nbd.2015.04.009 Verfaillie, S.C.J., Adriaanse, S.M., Binnewijzend, M.A.A., Benedictus, M.R., Ossenkoppele, R., Wattjes, M.P., Pijnenburg, Y.A.L., Flier, W.M. van der, Lammertsma, A.A., Kuijer, J.P.A., Boellaard, R., Scheltens, P., Berckel, B.N.M. van & Barkhof, F. (2015). Cerebral perfusion and glucose metabolism in Alzheimer's disease and frontotemporal dementia: two sides of the same coin? European Radiology, 25 (10), 3050-3059. doi: 10.1007/s00330-015-3696-1 Vliet, A.C. van, Tannemaat, M.R., Duinen, S.G. van, Verhaagen, J., Malessy, M.J.A. & Winter, F. de (2015). Human Neuroma-in-Continuity Contains Focal Deficits in Myelination. Journal of Neuropathology and Experimental Neurology, 74 (9), 901-911. doi: 10.1097/NEN.0000000000000229 Vos, S.J.B., Verhey, F., Frolich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Ruther, E., Nobili, F., Morbelli, S., Frisoni, G. B., Drzezga, A., Didic, M., Berckel, B.N.M. van, Simmons, A., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Muscio, C., Herukka, S.K., Salmon, E., Bastin, C., Wallin, A., Nordlund, A., Mendonca, A. de, Silva, D., Santana, I., Lemos, R., Engelborghs, S., Mussele, S. Van der, Freund-Levi, Y., Wallin, A.K., Hampel, H., Flier, W.M. van der, Scheltens, P. & Visser, P.J. (2015). Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. Brain, 138, 1327-1338. doi: 10.1093/brain/awv029 Vriend, C., Gerrits, N.J.H.M., Berendse, H.W., Veltman, D.J., Heuvel, O.A. van den & Werf, Y.D. van der (2015). Failure of stop and go in de novo Parkinson's disease-a functional magnetic resonance imaging study. Neurobiology of Aging, 36 (1), 470-475. doi: 10.1016/j.neurobiolaging.2014.07.031 Willemse, E.A.J. & Teunissen, C.E. (2015). Biobanking of Cerebrospinal Fluid for Biomarker Analysis in Neurological Diseases. Advances in Experimental Medicine and Biology, 864, 79-93. doi: 10.1007/978-3-319-20579-3_7 Willemse, E.A.J., Koel-Simmelink, M.J.A., Durieux-Lu, S., Flier, W.M. van der & Teunissen, C.E. (2015). Standard biobanking conditions prevent evaporation of body fluid samples. Clinica Chimica Acta, 442, 141-145. doi: 10.1016/j.cca.2015.01.036 Wong, T.H., Verkerk, A.J.M.H., Rozemuller, A.J.M., Willemsen, R., Neumann, M., Bonifati, V. & Swieten, J. (2015). Reply: PRKAR1B mutations are a rare cause of FUS negative neuronal intermediate filament inclusion disease. Brain, 138, e358. doi: 10.1093/brain/awu333 Wu, Y.H., Vidal, J.S., Rotrou, J. de, Sikkes, S.A.M., Rigaud, A.S. & Plichart, M. (2015). A Tablet-PC-Based Cancellation Test Assessing Executive Functions in Older Adults. American Journal of Geriatric Psychiatry, 23 (11), 1154-1161. doi: 10.1016/j.jagp.2015.05.012 Zuurbier, L.A., Luik, A.I., Hofman, A., Franco, O.H., Someren, E.J.W. van & Tiemeier, H. (2015). Fragmentation and Stability of Circadian Activity Rhythms Predict Mortality The Rotterdam Study. American Journal of Epidemiology, 181 (1), 54-63. doi: 10.1093/aje/kwu245 Zwan, M.D., Villemagne, V.L., Dore, V., Buckley, R., Bourgeat, P., Veljanoski, R., Salvado, O., Williams, R., Margison, L., Rembach, A., Macaulay, S.L., Martins, R., Amesh, D., Flier, W.M. van der, Ellis, K.A., Scheltens, P., Masters, C.L. & Rowe, C.C. (2015). Subjective Memory Complaints in APOE epsilon 4 Carriers are Associated with High Amyloid-beta Burden. Journal of Alzheimer's Disease, 49 (4), 1115-1122. doi: 10.3233/JAD-150446
Scientific papers non-refereed Vaudano, E., Vannieuwenhuyse, B., Geyten, S. Van Der, Lei, J. van der, Visser, P.J., Streffer, J., Ritchie, C., McHale, D., Lovestone, S., Hofmann-Apitius, M., Truyen, L. & Goldman, M. (2015). Boosting 43
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translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform. Alzheimers & Dementia, 11 (9), 1121-1122. doi: 10.1016/j.jalz.2015.02.002
Scientific publications (books, monographs, book chapters, proceedings) Anson, B.G. & Barkhof, F. (2015). Neurodegenerative Diseases and Epilepsy. In Grainger & Allison's Diagnostic Radiology: Neuroimaging, 6th Edition (pp. -6). Deisenhammer, F., Sellebjerg, F., Teunissen, C.E. & Tumani, H. (Eds.). (2015). Cerebrospinal Fluid in Research. Heidelberg New York Dordrecht London: Springer. DrĂśes, R.M., Schols, P. & Scheltens, P. (Eds.). (2015). Meer kwaliteit van leven. Integratieve persoonsgerichte dementiezorg. Leusden: Diagnosis Uitgevers. Hegen, H., Teunissen, C.E., Sellebjerg, F., Tumani, H. & Deisenhammer, F. (2015). Guidelines on Cerebrospinal Fluid Analysis. In F. Deisenhammer, F. Sellebjerg, C.E. Teunissen & H. Tumani (Eds.), Cerebrospinal Fluidin Clinical Neurology (pp. 407-428). Heidelberg New York Dordrecht London: Springer. Niemantsverdriet, E., Struyfs, H., Duits, F.H., Teunissen, C.E. & Engelborghs, S. (2015). Techniques, Contraindications, and Complications of CSF Collection Procedures. In F. Deisenhammer, F. Sellebjerg & C.E. Teunissen (Eds.), Cerebrospinal Fluidin Clinical Neurology (pp. 35-57). Heidelberg New York Dordrecht London: Springer. Ossenkoppele, R. & Berckel, B.N.M. van (2015). Hersenen en veroudering. In A. Aleman & P.H. Hulshoff (Eds.), Beeldvorming van het brein (pp. 141-154). Utrecht: de Tijdstroom. Scheltens, P. (2015). Diagnostiek en classificatie van dementie. In Meer kwaliteit van leven. Integratieve persoonsgerichte dementiezorg (pp. -1). Willemse, E.A.J. & Teunissen, C.E. (2015). Importance of Pre-analytical Stability for CSF Biomarker Testing. In F. Deisenhammer, F. Sellebjerg, C.E. Teunissen & H. Tumani (Eds.), Cerebrospinal Fluidin Clinical Neurology (pp. 59-77). Heidelberg New York Dordrecht London: Springer. Wouterlood, F.G. (2015). A Survey of Current Neuroanatomical Tracing Techniques. In Neural Tracing Methods (pp. 1-49).
Professional publications Beer, M.H. de, Leeuwis, A.E. & Pijnenburg, Y. (2015). Een patient met visuele problemen: Eerste uiting van neurodegeneratieve aandoening. Nederlands Tijdschrift voor Geneeskunde, 159:A8878. Flier, W.M. van der, Prins, N.D., Hooghiemstra, A.M. & Leeuwis, A.E. (2015). Vasculaire dementie. In J.A.M. Vandermeulen & M.M.A. Derix (Eds.), Neuropsychologische casuistiek: Verdieping en praktijkgerichte gevalsbeschrijvingen (pp. 225-13). Hepp, D.H., Dijk, K. van, Stam, C.J., Oosten, B.W. van & Foncke, E.M.J. (2015). Progressieve cognitieve stoornissen bij een 17-jarige. Nederlands Tijdschrift voor Geneeskunde, 159:A8490. Hoog, A. van 't & Wilhelmus, M.M.M. (2015). Eiwitvouwing. Chemische Feitelijkheden, 77:314. Leentjens, A.F.G. & Heuvel, O.A. van den (2015). Dilemma's bij de behandeling van psychiatrische symptomen bij patiĂŤnten met de ziekte van Parkinson. Tijdschrift voor psychiatrie, 57 (2), 138-142.
Publications for the general public Scheltens, P. & Flier, W.M. van der (2015). Het alzheimermysterie. Amsterdam: de Arbeiderspers.
Inaugural lecture Flier, W.M. van der (2015). Het alzheimermysterie (23-09-2015). Amsterdam: Vrije Universiteit.
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Farewell lecture Blankenstein, M.A. (2015). Het bloed was weg (12-06-2015). Amsterdam: Vrije Universiteit.
Neuroinflammation Theses VU/VUmc PhD-student at VU (A) Nijland, P.G. (2015, April 02). Astrocytes in multiple sclerosis associated neurodegeneration: a star is born. VU University. Prom./coprom.: prof. dr. P. van der Valk, prof .dr. H.E. de Vries & dr. J. van Horssen. Popescu, V. (2015, Juni 29). Brain atrophy in multiple sclerosis: quantification, pathological substrate and clinical relevance. VU University. Prom./coprom.: prof. dr. F. Barkhof, dr. ir. H. Vrenken & prof. dr. B.M.J. Uitdehaag. Vogel, D.Y.S. (2015, Februari 20). Macrophage/Microglia Plasticity in Multiple Sclerosis. VU University. Prom./coprom.: prof. dr. C.D. Dijkstra & dr. S. Amor.
Theses external PhD-student at VU (B) Hagemeier, J. (2015, Januari 15). The Irony of Iron: MRI and Brain Iron in Multiple Sclerosis. VU University. Prom./coprom.: prof. dr. J.J.G. Geurts, prof. dr. F. Barkhof & R. Zivadinov.
Scientific papers refereed Asztely, F., Gilland, E., Wattjes, M.P. & Lycke, J. (2015). Rituximab treatment did not aggravate ongoing progressive multifocal leukoencephalopathy in a patient with multiple sclerosis. Journal of the Neurological Sciences, 353 (1-2), 155-157. doi: 10.1016/j.jns.2015.04.010 Baker, D. & Amor, S. (2015). Mouse Models of Multiple Sclerosis: Lost in Translation? Current Pharmaceutical Design, 21 (18), 2440-2452. doi: 10.2174/1381612821666150316122706 Tewarie, P., Schoonheim, M.M., Schouten, D.I., Polman, C.H., Balk, L.J., Uitdehaag, B.M.J., Geurts, J.J.G., Hillebrand, A., Barkhof, F. & Stam, C.J. (2015). Functional Brain Networks: Linking Thalamic Atrophy to Clinical Disability in Multiple Sclerosis, A Multimodal fMRI and MEG Study. Human Brain Mapping, 36 (2), 603-618. doi: 10.1002/hbm.22650 Balk, L.J., Steenwijk, M.D., Tewarie, P., Daams, M., Killestein, J., Wattjes, M.P., Vrenken, H., Barkhof, F., Polman, C.H., Uitdehaag, B.M.J. & Petzold, A.F.S. (2015). Bidirectional trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 86 (4), 419-424. doi: 10.1136/jnnp-2014-308189 Barkhof, F. & Reich, D.S. (2015). Can leptomeningeal enhancement be linked to multiple sclerosis? Neurology, 84 (8), 762-763. doi: 10.1212/WNL.0000000000001292 Barkhof, F. & Geurts, J.J.G. (2015). Laminar cortical damage in multiple sclerosis. Brain, 138, 828-829. doi: 10.1093/brain/awv031 Bisecco, A., Rocca, M.A., Pagani, E., Mancini, L., Enzinger, C., Gallo, A., Vrenken, H., Stromillo, M.L., Copetti, M., Thomas, D.L., Fazekas, F., Tedeschi, G., Barkhof, F., Stefano, N. De & Filippi, M. (2015). Connectivity-based parcellation of the thalamus in multiple sclerosis and its implications for cognitive impairment: A multicenter study. Human Brain Mapping, 36 (7), 2809-2825. doi: 10.1002/hbm.22809 Blezer, E.L.A., Deddens, L.H., Kooij, G., Drexhage, J., Pol, S.M.A. van der, Reijerkerk, A., Dijkhuizen, R.M. & Vries, H.E. de (2015). In vivo MR imaging of intercellular adhesion molecule-1 expression in an animal model of multiple sclerosis. Contrast media & molecular imaging, 10 (2), 111-121. doi: 10.1002/cmmi.1602
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Bosma, L.V.A.E., Sonder, J.M., Kragt, J.J., Polman, C.H. & Uitdehaag, B.M.J. (2015). Detecting clinicallyrelevant changes in progressive multiple sclerosis. Multiple Sclerosis, 21 (2), 171-179. doi: 10.1177/1352458514540969 Broux, B., Mizee, M.R., Vanheusden, M., Pol, S. van der, Horssen, J. van, Wijmeersch, B. Van, Somers, V., Vries, H.E. de, Stinissen, P. & Hellings, N. (2015). IL-15 Amplifies the Pathogenic Properties of CD4(+)CD28(-) T Cells in Multiple Sclerosis. Journal of Immunology, 194 (5), 2099-2109. doi: 10.4049/jimmunol.1401547 Bustamante, M.F., Morcillo-Suarez, C., Malhotra, S., Rio, J., Leyva, L., Fernandez, O., Zettl, U.K., Killestein, J., Brassat, D., Garcia-Merino, J.A., Sanchez, A.J., Urcelay, E, Villar, L.M., Alvarez-Cermeno, J.C., Farre, X., Lechner-Scott, J., Vandenbroeck, K., Rodriguez-Antiguedad, A., Drulovic, J.S., MartinelliBoneschi, F., Chan, A., Oksenberg, J., Navarro, A., Montalban, X. & Comabella, M. (2015). Pharmacogenomic study in patients with multiple sclerosis: Responders and nonresponders to IFNbeta. Neurology neuroimmunology & neuroinflammation, 2 (5), e154. doi: 10.1212/NXI.0000000000000154 Calabrese, M., Magliozzi, R., Ciccarelli, O., Geurts, J.J.G., Reynolds, R. & Martin, R. (2015). Exploring the origins of grey matter damage in multiple sclerosis. Nature Reviews Neuroscience, 16 (3), 147-158. doi: 10.1038/nrn3900 Canto, E., Tintore, M., Villar, L.M., Costa, C., Nurtdinov, R., Alvarez-Cermeno, J.C., Arrambide, G., Reverter, F., Deisenhammer, F., Hegen, H., Khademi, M., Olsson, T., Tumani, H., Rodriguez-Martin, E., Piehl, F., Bartos, A., Zimova, D., Kotoucova, J., Kuhle, J., Kappos, L., Garcia-Merino, J.A., Sanchez, A.J., Saiz, A., Blanco, Y., Hintzen, R., Jafari, N., Brassat, D., Lauda, F., Roesler, R., Rejdak, K., Papuc, E., Andres, C. de, Rauch, S., Khalil, M., Enzinger, C., Galimberti, D., Scarpini, E., Teunissen, C., Sanchez, A., Rovira, A., Montalban, X. & Comabella, M. (2015). Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes. Brain, 138, 918-931. doi: 10.1093/brain/awv017 Clarner, T., Janssen, K., Nellessen, L., Stangel, M., Skripuletz, T., Krauspe, B., Hess, F.M., Denecke, B., Beutner, C., Linnartz-Gerlach, B., Neumann, H., Vallieres, L., Amor, S., Ohl, K., Tenbrock, K., Beyer, C. & Kipp, M. (2015). CXCL10 Triggers Early Microglial Activation in the Cuprizone Model. Journal of Immunology, 194 (7), 3400-3413. doi: 10.4049/jimmunol.1401459 Cohen, A.F., Burggraaf, J., Gerven, J.M.A. van, Moerland, M. & Groeneveld, G.J. (2015). The Use of Biomarkers in Human Pharmacology (Phase I) Studies. Annual Review of Pharmacology and Toxicology, 55, 55-74. doi: 10.1146/annurev-pharmtox-011613-135918 Cohen, J., Belova, A., Selmaj, K., Wolf, C., Sormani, M.P., Oberye, J., Tweel, E. van den, Mulder, R., Koper, N., Voortman, G. & Barkhof, F. (2015). Equivalence of Generic Glatiramer Acetate in Multiple Sclerosis A Randomized Clinical Trial. JAMA Neurology, 72 (12), 1433-1441. doi: 10.1001/jamaneurol.2015.2154 Coppens, S., Petzold, A.F.S. & Knoppert, W.A.E.J. (2015). Pain in Optic Perineuritis: Author Response. Neuro-ophthalmology, 39 (2), 101-102. doi: 10.3109/01658107.2015.1004589 Daams, M., Steenwijk, M.D., Wattjes, M.P., Geurts, J.J.G., Uitdehaag, B.M.J., Tewarie, P.K., Balk, L.J., Pouwels, P.J.W., Killestein, J. & Barkhof, F. (2015). Unraveling the neuroimaging predictors for motor dysfunction in long- standing multiple sclerosis. Neurology, 85 (3), 248-255. doi: 10.1212/WNL.0000000000001756 Douw, L., DeSalvo, M.N., Tanaka, N., Cole, A.J., Liu, H.S., Reinsberger, C. & Stufflebeam, S.M. (2015). Dissociated multimodal hubs and seizures in temporal lobe epilepsy. Annals of Clinical and Translational Neurology, 2 (4), 338-352. doi: 10.1002/acn3.173 Douw, L., Leveroni, C.L., Tanaka, N., Emerton, B.C., Cole, A.C., Reinsberger, C. & Stufflebeam, S.M. (2015). Loss of Resting-State Posterior Cingulate Flexibility Is Associated with Memory Disturbance in Left Temporal Lobe Epilepsy. PLoS One, 10 (6):e0131209. doi: 10.1371/journal.pone.0131209 Enzinger, C., Barkhof, F., Ciccarelli, O., Filippi, M., Kappos, L., Rocca, M.A., Ropele, S., Rovira, A., Schneider, T., Stefano, N. De, Vrenken, H., Wheeler-Kingshott, C., Wuerfel, J. & Fazekas, F. (2015). Nonconventional MRI and microstructural cerebral changes in multiple sclerosis. Nature Reviews Neurology, 11 (12), 676-686. doi: 10.1038/nrneurol.2015.194 Esposito, E., Vries, H.E. de, Pol, S.M.A. van der, Boschi, F., Calderan, L., Mannucci, S., Drechsler, M., Contado, C., Cortesi, R. & Nastruzzi, C. (2015). Production, Physico-Chemical Characterization and
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Biodistribution Studies of Lipid Nanoparticles. Journal of Nanomedicine & Nanotechnology, 6 (1), 256. doi: 10.4172/2157-7439.1000256 Gass, A., Rocca, M.A., Agosta, F., Ciccarelli, O., Chard, D., Valsasina, P., Brooks, J.C.W., Bischof, A., Eisele, P., Kappos, L., Barkhof, F., Filippi, M. & Vrenken, H. (2015). MRI monitoring of pathological changes in the spinal cord in patients with multiple sclerosis. Lancet Neurology, 14 (4), 443-454. doi: 10.1016/S1474-4422(14)70294-7 Haarmann, A., Nowak, E., Deiss, A., Pol, S. van der, Monoranu, C.M., Kooij, G., Muller, N., Valk, P. van der, Stoll, G., Vries, H.E. de, Berberich-Siebelt, F. & Buttmann, M. (2015). Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin alpha-4-transduced outside-in signalling. Acta Neuropathologica, 129 (5), 639-652. doi: 10.1007/s00401-015-1417-0 Haller, S., Barkhof, F., Wattjes, M.P. & Lalive, P.H. (2015). Transient gadolinium leakage in natalizumabtreated multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 86 (4), 475-476. doi: 10.1136/jnnp-2014-309069 Hart, B.A. 't, Kooyk, Y. van, Geurts, J.J.G. & Gran, B. (2015). The primate autoimmune encephalomyelitis model; a bridge between mouse and man. Annals of Clinical and Translational Neurology, 2 (5), 581-593. doi: 10.1002/acn3.194 Heide, A., Donjacour, C.E.H.M., Pijl, H., Reijntjes, R.H.A.M., Overeem, S., Lammers, G.J., Someren, E.J.W. van & Fronczek, R. (2015). The effects of sodium oxybate on core body and skin temperature regulation in narcolepsy. Journal of Sleep Research, 24 (5), 566-575. doi: 10.1111/jsr.12303 Hulst, H.E., Schoonheim, M.M., Geest, Q. van, Uitdehaag, B.M.J., Barkhof, F. & Geurts, J.J.G. (2015). Memory impairment in multiple sclerosis: Relevance of hippocampal activation and hippocampal connectivity. Multiple Sclerosis, 21 (13), 1705-1712. doi: 10.1177/1352458514567727 Jain, S., Sima, D.M., Ribbens, A., Cambron, M., Maertens, A., Van Hecke, W., De Meij, J., Barkhof, F., Steenwijk, M.D., Daams, M., Maes, F., Van Huffel, S., Vrenken, H. & Smeets, D. (2015). Automatic segmentation and volumetry of multiple sclerosis brain lesions from MR images. NeuroImage: Clinical, 8, 367-375. doi: 10.1016/j.nicl.2015.05.003 Janssens, K., Haute, C. Van den, Baekelandt, V., Lucas, S., Horssen, J. van, Somers, V., Wijmeersch, B. Van, Stinissen, P., Hendriks, J.J.A., Slaets, H. & Hellings, N. (2015). Leukemia inhibitory factor tips the immune balance towards regulatory T cells in multiple sclerosis. Brain Behavior and Immunity, 45, 180-188. doi: 10.1016/j.bbi.2014.11.010 Jokinen, H., Goncalves, N., Vigario, R., Lipsanen, J., Fazekas, F., Schmidt, R., Barkhof, F., Madureira, S., Verdelho, A., Inzitari, D., Pantoni, L. & Erkinjuntti, T. (2015). Early-Stage White Matter Lesions Detected by Multispectral MRI Segmentation Predict Progressive Cognitive Decline. Frontiers in Neuroscience, 9, 455. doi: 10.3389/fnins.2015.00455 Jonkman, L.E., Lopez Soriano, A., Amor, S., Barkhof, F., Valk, P. van der, Vrenken, H. & Geurts, J.J.G. (2015). Can MS lesion stages be distinguished with MRI? A postmortem MRI and histopathology study. Journal of Neurology, 262 (4), 1074-1080. doi: 10.1007/s00415-015-7689-4 Jonkman, L.E., Rosenthal, D.M., Sormani, M.P., Miles, L., Herbert, J., Grossman, R.I. & Inglese, M. (2015). Gray Matter Correlates of Cognitive Performance Differ between Relapsing-Remitting and PrimaryProgressive Multiple Sclerosis. PLoS One, 10 (10):e0129380. doi: 10.1371/journal.pone.0129380 Jonkman, L.E., Klaver, R., Fleysher, L., Inglese, M. & Geurts, J.J.G. (2015). Ultra-High-Field MRI Visualization of Cortical Multiple Sclerosis Lesions with T2 and T2*: A Postmortem MRI and Histopathology Study. American Journal of Neuroradiology, 36 (11), 2062-2067. doi: 10.3174/ajnr.A4418 Junemann, A.G.M., Rejdak, R., Huchzermeyer, C., Maciejewski, R., Grieb, P., Kruse, F.E., Zrenner, E., Rejdak, K. & Petzold, A.F.S. (2015). Elevated vitreous body glial fibrillary acidic protein in retinal diseases. Graefe's Archive for Clinical and Experimental Ophthalmology, 253 (12), 2181-2186. doi: 10.1007/s00417-015-3127-7 Kamphuis, W.W., Troletti, C.D., Reijerkerk, A., Romero, I.A. & Vries, H.E. de (2015). The Blood-Brain Barrier in Multiple Sclerosis: microRNAs as Key Regulators. CNS and Neurological Disorders. Drug Targets, 14 (2), 157-167. doi: 10.2174/1871527314666150116125246 Kappos, L., Kuhle, J., Multanen, J., Kremenchutzky, M., Cantogno, E.V. di, Cornelisse, P., Lehr, L., CassetSemanaz, F., Issard, D. & Uitdehaag, B.M.J. (2015). Factors influencing long-term outcomes in
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relapsing-remitting multiple sclerosis: PRISMS-15. Journal of Neurology, Neurosurgery and Psychiatry, 86 (11), 1202-1207. doi: 10.1136/jnnp-2014-310024 Kappos, L., O'Connor, P., Radue, E.W., Polman, C., Hohlfeld, R., Selmaj, K., Ritter, S., Schlosshauer, R., Rosenstiel, P. von, Zhang-Auberson, L. & Francis, G. (2015). Long-term effects of fingolimod in multiple sclerosis The randomized FREEDOMS extension trial. Neurology, 84 (15), 1582-1591. doi: 10.1212/WNL.0000000000001462 Killestein, J. & Wattjes, M.P. (2015). Low JC virus antibody index during natalizumab treatment less safe than assumed? Multiple Sclerosis, 21 (14), 1753-1754. doi: 10.1177/1352458515611499 Kilsdonk, I.D., Steenwijk, M.D., Pouwels, P.J.W., Zwanenburg, J.J.M., Visser, F., Luijten, P.R., Geurts, J.J.G., Barkhof, F. & Wattjes, M.P. (2015). Perivascular spaces in MS patients at 7 Tesla MRI: A marker of neurodegeneration? Multiple Sclerosis, 21 (2), 155-162. doi: 10.1177/1352458514540358 Klaver, R., Popescu, V., Voorn, P., Graaf, Y. van der, Valk, P. van der, Vries, H.E. de, Schenk, G.J. & Geurts, J.J.G. (2015). Neuronal and Axonal Loss in Normal-Appearing Gray Matter and Subpial Lesions in Multiple Sclerosis. Journal of Neuropathology and Experimental Neurology, 74 (5), 453-458. doi: 10.1097/NEN.0000000000000189 Kooij, G. & Vries, H.E. de (2015). The best basic science paper in multiple sclerosis in 2014: Important role for the choroid plexus in the central nervous system entry of leukocytes. Multiple Sclerosis, 21 (4), 372-373. doi: 10.1177/1352458515573095 Kooij, G., Braster, R., Koning, J.J., Laan, L.C., Vliet, S.J. van, Los, T., Eveleens, A.M., Pol, S.M.A. van der, Forster-Waldl, E., Boztug, K., Belot, A., Szilagyi, K., Berg, T.K. van den, Buul, J.D. van, Egmond, M. van, Vries, H.E. de, Cummings, R.D., Dijkstra, C.D. & Die, I. van (2015). Trichuris suis induces human non-classical patrolling monocytes via the mannose receptor and PKC: implications for multiple sclerosis. Acta Neuropathologica Communinications, 3, 45. doi: 10.1186/s40478-015-0223-1 Kroksveen, A.C., Jaffe, J.D., Aasebo, E., Barsnes, H., Bjorlykke, Y., Franciotta, D., Keshishian, H., Myhr, K.M., Opsahl, J.A., Pesch, V. van, Teunissen, C.E., Torkildsen, O., Ulvik, R.J., Vethe, H., Carr, S.A. & Berven, F.S. (2015). Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis. Proteomics, 15 (19), 3361-3369. doi: 10.1002/pmic.201400142 Kuhle, J., Disanto, G., Dobson, R., Adiutori, R., Bianchi, L., Topping, J., Bestwick, J.P., Meier, U.C., Marta, M., Costa, G. Dalla, Runia, T., Evdoshenko, E., Lazareva, N., Thouvenot, E., Iaffaldano, P., Direnzo, V., Khademi, M., Piehl, F., Comabella, M., Sombekke, M., Killestein, J., Hegen, H., Rauch, S., D'Alfonso, S., Alvarez-Cermeno, J.C., Kleinova, P., Horakova, D., Roesler, R., Lauda, F., Llufriu, S., Avsar, T., Uygunoglu, U., Altintas, A., Saip, S., Menge, T., Rajda, C., Bergamaschi, R., Moll, N., Khalil, M., Marignier, R., Dujmovic, I., Larsson, H., Malmestrom, C., Scarpini, E., Fenoglio, C., Wergeland, S., Laroni, A., Annibali, V., Romano, S., Martinez, A.D., Carra, A., Salvetti, M., Uccelli, A., Torkildsen, O., Myhr, K.M., Galimberti, D., Rejdak, K., Lycke, J., Frederiksen, J.L., Drulovic, J., Confavreux, C., Brassat, D., Enzinger, C., Fuchs, S., Bosca, I., Pelletier, J., Picard, C., Colombo, E., Franciotta, D., Derfuss, T., Lindberg, R.L.P., Yaldizli, O., Vecsei, L., Kieseier, B.C., Hartung, H.P., Villoslada, P., Siva, A., Saiz, A., Tumani, H., Havrdova, E., Villar, L.M., Leone, M., Barizzone, N., Deisenhammer, F., Teunissen, C., Montalban, X., Tintore, M., Olsson, T., Trojano, M., Lehmann, S., Castelnovo, G., Lapin, S., Hintzen, R., Kappos, L., Furlan, R., Martinelli, V., Comi, G., Ramagopalan, S.V. & Giovannoni, G. (2015). Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study. Multiple Sclerosis, 21 (8), 1013-1024. doi: 10.1177/1352458514568827 Lalive, P.H., Bridel, C., Ferfoglia, R.I., Kaiser, L., Pasquier, R. Du, Barkhof, F. & Haller, S. (2015). Minimal supportive treatment in natalizumab-related PML in a MS patient. Journal of Neurology, Neurosurgery and Psychiatry, 86 (3), 354-355. doi: 10.1136/jnnp-2014-308154 Lim, J.L., Pol, S.M.A. van der, Di Dio, F., Hof, B. van het, Kooij, G., Vries, H.E. de & Horssen, J. van (2015). Protective effects of monomethyl fumarate at the inflamed blood-brain barrier. Microvascular Research, 105, 61-68. doi: 10.1016/j.mvr.2015.12.003 Liu, Y., Wang, J.H., Daams, M., Weiler, F., Hahn, H.K., Duan, Y.Y., Huang, J., Ren, Z.Q., Ye, J., Dong, H.Q., Vrenken, H., Wattjes, M.P., Shi, F.D., Li, K.C. & Barkhof, F. (2015). Differential patterns of spinal cord and brain atrophy in NMO and MS. Neurology, 84 (14), 1465-1472. doi: 10.1212/WNL.0000000000001441
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Liu, Y., Fu, Y., Schoonheim, M.M., Zhang, N., Fan, M.L., Su, L., Shen, Y., Yan, Y.P., Yang, L., Wang, Q.H., Zhang, N.N.N., Yu, C.S., Barkhof, F. & Shi, F.D. (2015). Structural MRI substrates of cognitive impairment in neuromyelitis optica. Neurology, 85 (17), 1491-1499. doi: 10.1212/WNL.0000000000002067 Liu, Y.O., Duan, Y.Y., Huang, J., Ren, Z.Q., Ye, J., Dong, H.Q., Shi, F.D., Barkhof, F., Vrenken, H., Wattjes, M.P., Wang, J.H. & Li, K.C. (2015). Multimodal Quantitative MR Imaging of the Thalamus in Multiple Sclerosis and Neuromyelitis Optica. Radiology, 277 (3), 784-792. doi: 10.1148/radiol.2015142786 Loram, L.C., Strand, K.A., Taylor, F.R., Sloane, E., Dam, A.M. van, Rieger, J., Maier, S.F. & Watkins, L.R. (2015). Adenosine 2A receptor agonism: A single intrathecal administration attenuates motor paralysis in experimental autoimmune encephalopathy in rats. Brain Behavior and Immunity, 46, 50-54. doi: 10.1016/j.bbi.2015.01.014 Lucassen, P.J., Oomen, C.A., Naninck, E.F.G., Fitzsimons, C.P., Dam, A.M. van, Czeh, B. & Korosi, A. (2015). Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation. Cold Spring Harbor Perspectives in Biology, 7 (9), a021303. doi: 10.1101/cshperspect.a021303 Lukas, C., Knol, D.L., Sombekke, M.H., Bellenberg, B., Hahn, H.K., Popescu, V., Weier, K., Radue, E.W., Gass, A., Kappos, L., Naegelin, Y., Uitdehaag, B.M.J., Geurts, J.J.G., Barkhof, F. & Vrenken, H. (2015). Cervical spinal cord volume loss is related to clinical disability progression in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry, 86 (4), 410-418. doi: 10.1136/jnnp-2014308021 Malaspina, A., Puentes, F. & Amor, S. (2015). Disease origin and progression in amyotrophic lateral sclerosis: an immunology perspective. International Immunology, 27 (3), 117-129. doi: 10.1093/intimm/dxu099 Malekzadeh, A., Geer-Peeters, W.V. de, Groot, V. de, Teunissen, C.E. & Beckerman, H. (2015). Fatigue in Patients with Multiple Sclerosis: Is It Related to Pro- and Anti-Inflammatory Cytokines? Disease markers, 2015, 1-7. doi: 10.1155/2015/758314 Malhotra, S., Rio, J., Urcelay, E, Nurtdinov, R., Bustamante, M.F., Fernandez, O., Oliver, B., Zettl, U., Brassat, D., Killestein, J., Lechner-Scott, J., Drulovic, J., Chan, A., Martinelli-Boneschi, F., GarciaMerino, A., Montalban, X. & Comabella, M. (2015). NLRP3 inflammasome is associated with the response to IFN-beta in patients with multiple sclerosis. Brain, 138, 644-652. doi: 10.1093/brain/awu388 Michailidou, I., Vries, H.E. de, Hol, E.M. & Strien, M.E. van (2015). Activation of endogenous neural stem cells for multiple sclerosis therapy. Frontiers in Neuroscience, 8, 454. doi: 10.3389/fnins.2014.00454 Michailidou, I., Willems, J.G.P., Kooi, E.J., Eden, C. van, Gold, S.M., Geurts, J.J.G., Baas, F., Huitinga, I. & Ramaglia, V. (2015). Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus. Annals of Neurology, 77 (6), 1007-1026. doi: 10.1002/ana.24398 Munger, K.L., Fitzgerald, K.C., Freedman, M.S., Hartung, H.P., Miller, D. H., Montalban, X., Edan, G., Barkhof, F., Suarez, G., Radue, E.W., Sandbrink, R., Kappos, L., Pohl, C. & Ascherio, A. (2015). No association of multiple sclerosis activity and progression with EBV or tobacco use in BENEFIT. Neurology, 85 (19), 1694-1701. doi: 10.1212/WNL.0000000000002099 Munster, C.E.P. van, Jonkman, L.E., Weinstein, H.C., Uitdehaag, B.M.J. & Geurts, J.J.G. (2015). Grey matter damage in multiple sclerosis: Impact on clinical symptoms. Neuroscience, 303, 446-461. doi: 10.1016/j.neuroscience.2015.07.006 Nieuwkamp, D.J., Murk, J.L. & Oosten, B.W. van (2015). PML in a Patient without Severe Lymphocytopenia Receiving Dimethyl Fumarate. New England Journal of Medicine, 372 (15), 14741476. doi: 10.1056/NEJMc1413724 Nijland, P.G., Molenaar, R.J., Pol, S.M.A. van der, Valk, P. van der, Noorden, C.J.F. van, Vries, H.E. de & Horssen, J. van (2015). Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions. Acta Neuropathologica Communinications, 3, 79. doi: 10.1186/s40478-015-02618 Overvliet, G.M., Vries, M. de, Wattjes, M.P. & Vermeulen, R.J. (2015). Cervical Synovial Cyst in a 16-YearOld Girl. Pediatric Neurology, 53 (2), 173-174. doi: 10.1016/j.pediatrneurol.2015.02.025
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Pedrini, M.J.F., Seewann, A., Bennett, K.A., Wood, A.J.T., James, I., Burton, J., Marshall, B.J., Carroll, W.M. & Kermode, A.G. (2015). Helicobacter pylori infection as a protective factor against multiple sclerosis risk in females. Journal of Neurology, Neurosurgery and Psychiatry, 86 (6), 603-607. doi: 10.1136/jnnp-2014-309495 Peferoen, L.A.N., Vogel, D.Y.S., Ummenthum, K., Breur, M., Heijnen, P.D.A.M., Gerritsen, W.H., PeferoenBaert, R.M.B., Valk, P. van der, Dijkstra, C.D. & Amor, S. (2015). Activation Status of Human Microglia Is Dependent on Lesion Formation Stage and Remyelination in Multiple Sclerosis. Journal of Neuropathology and Experimental Neurology, 74 (1), 48-63. doi: 10.1097/NEN.0000000000000149 Peferoen, L.A.N., Gerritsen, W.H., Breur, M., Ummenthum, K.M.D., Peferoen-Baert, R.M.B., Valk, P. van der, Noort, J.M. van & Amor, S. (2015). Small heat shock proteins are induced during multiple sclerosis lesion development in white but not grey matter. Acta Neuropathologica Communinications, 3 (1), 87. doi: 10.1186/s40478-015-0267-2 Petzold, A.F.S. (2015). The prognostic value of CSF neurofilaments in multiple sclerosis at 15-year followup. Journal of Neurology, Neurosurgery and Psychiatry, 86 (12), 1388-1390. doi: 10.1136/jnnp2014-309827 Petzold, A.F.S., Nijland, P.G., Balk, L.J., Amorini, A.M., Lazzarino, G., Wattjes, M.P., Gasperini, C., Valk, P. van der, Tavazzi, B., Lazzarino, G. & Horssen, J. van (2015). Visual pathway neurodegeneration winged by mitochondrial dysfunction. Annals of Clinical and Translational Neurology, 2 (2), 140150. doi: 10.1002/acn3.157 Poon, K.W., Brideau, C., Schenk, G.J., Klaver, R., Klauser, A.M., Kawasoe, J., Geurts, J.J.G. & Stys, P.K. (2015). Quantitative biochemical investigation of various neuropathologies using high-resolution spectral CARS microscopy. Proceedings of SPIE - International Society for Optical Engineering, 9305:930504. doi: 10.1117/12.2076654 Popescu, V., Klaver, R., Voorn, P., Graaf, Y. van der, Knol, D.L., Twisk, J.W.R., Versteeg, A., Schenk, G.J., Valk, P. van der, Barkhof, F., Vries, H.E. de, Vrenken, H. & Geurts, J.J.G. (2015). What drives MRImeasured cortical atrophy in multiple sclerosis? Multiple Sclerosis, 21 (10), 1280-1290. doi: 10.1177/1352458514562440 Prins, M., Schul, E., Geurts, J., Valk, P. van der, Drukarch, B. & Dam, A.M. van (2015). Pathological differences between white and grey matter multiple sclerosis lesions. Annals of the New York Academy of Sciences, 1351, 99-113. doi: 10.1111/nyas.12841 Radue, E.W., Barkhof, F., Kappos, L., Sprenger, T., Haring, D.A., Vera, A. de, Rosenstiel, P. von, Bright, J.R., Francis, G. & Cohen, J.A. (2015). Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. Neurology, 84 (8), 784-793. doi: 10.1212/WNL.0000000000001281 Raj, D.D., Moser, J., Pol, S.M.A. van der, Os, R.P. van, Holtman, I.R., Brouwer, N., Oeseburg, H., Schaafsma, W., Wesseling, E.M., Dunnen, W. den, Biber, K.P., Vries, H.E. de, Eggen, B.J. & Boddeke, H.W.G.M. (2015). Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood-brain barrier dysregulation in a mouse model of telomere shortening. Aging Cell, 14 (6), 1003-1013. doi: 10.1111/acel.12370 Rao-Ruiz, P., Carney, K.E., Pandya, N.J., Loo, R.J., Verheijen, M.H.G., Nierop, P. van, Smit, A.B. & Spijker, S. (2015). Time-dependent changes in the mouse hippocampal synaptic membrane proteome after contextual fear conditioning. Hippocampus, 25 (11), 1250-1261. doi: 10.1002/hipo.22432. Reuter, E., Weber, J., Paterka, M., Ploen, R., Breiderhoff, T., Horssen, J. van, Willnow, T.E., Siffrin, V. & Zipp, F. (2015). Role of Sortilin in Models of Autoimmune Neuroinflammation. Journal of Immunology, 195 (12), 5762-5769. doi: 10.4049/jimmunol.1403156 Rocca, M.A., Amato, M.P., Stefano, N. De, Enzinger, C., Geurts, J.J., Penner, I.K., Rovira, A., Sumowski, J.F., Valsasina, P. & Filippi, M. (2015). Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis. Lancet Neurology, 14 (3), 302-317. doi: 10.1016/S1474-4422(14)70250-9 Roosendaal, S.D. & Barkhof, F. (2015). Imaging Phenotypes in Multiple Sclerosis. Neuroimaging Clinics of North America, 25 (1), 83-96. doi: 10.1016/j.nic.2014.09.008 Rovira, A., Wattjes, M.P., Tintore, M., Tur, C., Yousry, T.A., Sormani, M.P., Stefano, N. De, Filippi, M., Auger, C., Rocca, M.A., Barkhof, F., Fazekas, F., Kappos, L., Polman, C., Miller, D. & Montalban, X. (2015). MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis-clinical
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implementation in the diagnostic process. Nature Reviews Neurology, 11 (8), 471-482. doi: 10.1038/nrneurol.2015.106 Schaafsma, W., Zhang, X., Zomeren, K.C. van, Jacobs, S., Georgieva, P.B., Wolf, S.A., Kettenmann, H., Janova, H., Saiepour, N., Hanisch, U.K., Meerlo, P., Elsen, P.J. van den, Brouwer, N., Boddeke, H.W.G.M. & Eggen, B.J.L. (2015). Long-lasting pro-inflammatory suppression of microglia by LPSpreconditioning is mediated by RelB-dependent epigenetic silencing. Brain Behavior and Immunity, 48, 205-221. doi: 10.1016/j.bbi.2015.03.013 Schippling, S., Balk, L.J., Costello, F., Albrecht, P., Balcer, L., Calabresi, P.A., Frederiksen, J., Frohman, E., Green, A.J., Klistorner, A., Outteryck, O., Paul, F., Plant, G.T., Traber, G., Vermersch, P., Villoslada, P., Wolf, S. & Petzold, A.F.S. (2015). Quality control for retinal OCT in multiple sclerosis: validation of the OSCAR-IB criteria. Multiple Sclerosis, 21 (2), 163-170. doi: 10.1177/1352458514538110 Schoonheim, M.M., Meijer, K.A. & Geurts, J.J.G. (2015). Network collapse and cognitive impairment in multiple sclerosis. Frontiers in Neurology, 6, 82. doi: 10.3389/fneur.2015.00082 Schoonheim, M.M., Hulst, H.E., Brandt, R.B., Strik, M., Wink, A.M., Uitdehaag, B.M.J., Barkhof, F. & Geurts, J.J.G. (2015). Thalamus structure and function determine severity of cognitive impairment in multiple sclerosis. Neurology, 84 (8), 776-783. doi: 10.1212/WNL.0000000000001285 Schottlaender, L.V., Petzold, A.F.S., Wood, N. & Houlden, H. (2015). Diagnostic clues and manifesting carriers in fukutin-related protein (FKRP) limb-girdle muscular dystrophy. Journal of the Neurological Sciences, 348 (1-2), 266-268. doi: 10.1016/j.jns.2014.12.008 Slowik, A., Schmidt, T., Beyer, C., Amor, S., Clarner, T. & Kipp, M. (2015). The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. British Journal of Pharmacology, 172 (1), 80-92. doi: 10.1111/bph.12938 Sonder, J.M., Balk, L.J., Linden, F.A.H. van der, Bosma, L.V.A.E., Polman, C.H. & Uitdehaag, B.M.J. (2015). Toward the use of proxy reports for estimating long-term patient-reported outcomes in multiple sclerosis. Multiple Sclerosis, 21 (14), 1865-1871. doi: 10.1177/1352458514544078 Steenwijk, M.D., Daams, M., Pouwels, P.J.W., Balk, L.J., Tewarie, P.K., Geurts, J.J.G., Barkhof, F. & Vrenken, H. (2015). Unraveling the Relationship Between Regional Gray Matter Atrophy and Pathology in Connected White Matter Tracts in Long-Standing Multiple Sclerosis. Human Brain Mapping, 36 (5), 1796-1807. doi: 10.1002/hbm.22738 Strien, M.E. van, Vries, H.E. de, Chrobok, N.L., Bol, J.G.J.M., Breve, J.J.P., Pol, S.M.A. van der, Kooij, G., Buul, J.D. van, Karpuj, M., Steinman, L., Wilhelmus, M.M., Sestito, C., Drukarch, B. & Dam, A.M. van (2015). Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration. Brain Behavior and Immunity, 50, 141-154. doi: 10.1016/j.bbi.2015.06.023 Tellingen, O. van, Yetkin-Arik, B., Gooijer, M.C. de, Wesseling, P., Wurdinger, T. & Vries, H.E. de (2015). Overcoming the blood-brain tumor barrier for effective glioblastoma treatment. Drug Resistance Updates, 19, 1-12. doi: 10.1016/j.drup.2015.02.002 Teunissen, C.E., Malekzadeh, A., Leurs, C., Bridel, C. & Killestein, J. (2015). Body fluid biomarkers for multiple sclerosis-the long road to clinical application. Nature Reviews Neurology, 11 (10), 585596. doi: 10.1038/nrneurol.2015.173 Vennegoor, A., Rispens, T., Oosten, B.W. van, Wattjes, M.P., Wondergem, M.J., Teunissen, C.E., Kleij, D. van der, Uitdehaag, B.M.J., Polman, C.H. & Killestein, J. (2015). Application of serum natalizumab levels during plasma exchange in MS patients with progressive multifocal leukoencephalopathy. Multiple Sclerosis, 21 (4), 481-484. doi: 10.1177/1352458514541507 Vennegoor, A., Rossum, J.A. van, Polman, C.H., Wattjes, M.P. & Killestein, J. (2015). Longitudinal JCV serology in multiple sclerosis patients preceding natalizumab-associated progressive multifocal leukoencephalopathy. Multiple Sclerosis, 21 (12), 1600-1603. doi: 10.1177/1352458514567728 Vogel, D.Y.S., Kooij, G., Heijnen, P.D.A.M., Breur, M., Peferoen, L.A.N., Valk, P. van der, Vries, H.E. de, Amor, S. & Dijkstra, C.D. (2015). GM-CSF promotes migration of human monocytes across the blood brain barrier. European Journal of Immunology, 45 (6), 1808-1819. doi: 10.1002/eji.201444960 Warnke, C., Stettner, M., Lehmensiek, V., Dehmel, T., Mausberg, A.K., Geldern, G. von, Gold, R., Kumpfel, T., Hohlfeld, R., Maurer, M., Stangel, M., Straeten, V., Limmroth, V., Weber, T., Kleinschnitz, C., Wattjes, M.P., Svenningsson, A., Olsson, T., Hartung, H.P., Hermsen, D., Tumani, H., Adams, O. &
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Kieseier, B.C. (2015). Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF. Multiple Sclerosis, 21 (8), 1036-1044. doi: 10.1177/1352458514556296 Wattjes, M.P., Rovira, A., Miller, D., Yousry, T.A., Sormani, M.P., Stefano, N. De, Tintore, M., Auger, C., Tur, C., Filippi, M., Rocca, M.A., Fazekas, F., Kappos, L., Polman, C., Barkhof, F. & Montalban, X. (2015). Evidence-Based Guidelines Magnims Consensus Guidelines on the Use of Mri in Multiple Sclerosis-Establishing Disease Prognosis and Monitoring Patients. Nature Reviews Neurology, 11 (10), 597-606. doi: 10.1038/nrneurol.2015.157 Wattjes, M.P. (2015). Left atrial myxoma presenting with white matter lesions suggestive of multiple sclerosis: The differential diagnosis goes beyond MRI. Multiple Sclerosis, 21 (2), 255-255. doi: 10.1177/1352458514543342 Wattjes, M.P., Steenwijk, M.D. & Stangel, M. (2015). MRI in the Diagnosis and Monitoring of Multiple Sclerosis: An Update. Clinical neuroradiology, 25, 157-165. doi: 10.1007/s00062-015-0430-y Wattjes, M.P., Vennegoor, A., Steenwijk, M.D., Vos, M., Killestein, J., Oosten, B.W. van, Mostert, J., Siepman, D.A., Moll, W., Golde, A.E.L. van, Frequin, S.T.F.M., Richert, N.D. & Barkhof, F. (2015). MRI pattern in asymptomatic natalizumab-associated PML. Journal of Neurology, Neurosurgery and Psychiatry, 86 (7), 793-798. doi: 10.1136/jnnp-2014-308630 Weiler, F., Daams, M., Lukas, C., Barkhof, F. & Hahn, H.K. (2015). Highly accurate volumetry of the spinal cord. Proceedings of SPIE - International Society for Optical Engineering, 9413:941302. doi: 10.1117/12.2080803 Wiebenga, O.T., Klauser, A.M., Schoonheim, M.M., Nagtegaal, G.J.A., Steenwijk, M.D., Rossum, J.A. van, Polman, C.H., Barkhof, F., Pouwels, P.J.W. & Geurts, J.J.G. (2015). Enhanced Axonal Metabolism during Early Natalizumab Treatment in Relapsing-Remitting Multiple Sclerosis. American Journal of Neuroradiology, 36 (6), 1116-1123. doi: 10.3174/ajnr.A4252 Wierda, R.J., Rietveld, I.M., Eggermond, M.C.J.A. van, Belien, J.A.M., Zwet, E.W. van, Lindeman, J.H.N. & Elsen, P.J. van den (2015). Global histone H3 lysine 27 triple methylation levels are reduced in vessels with advanced atherosclerotic plaques. Life Sciences, 129, 3-9. doi: 10.1016/j.lfs.2014.10.010 Wijburg, M.T., Oosten, B.W. van, Murk, J.L., Karimi, O., Killestein, J. & Wattjes, M.P. (2015). Heterogeneous imaging characteristics of JC virus granule cell neuronopathy (GCN): a case series and review of the literature. Journal of Neurology, 262 (1), 65-73. doi: 10.1007/s00415-014-7530-5 Wu, D.S., Cerutti, C., Lopez-Ramirez, M.A., Pryce, G., King-Robson, J., Simpson, J.E., Pol, S.M.A. van der, Hirst, M.C., Vries, H.E. de, Sharrack, B., Baker, D., Male, D.K., Michael, G.J. & Romero, I.A. (2015). Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-kappa B activation. Journal of Cerebral Blood Flow and Metabolism, 35 (3), 412-423. doi: 10.1038/jcbfm.2014.207 Zhang, N., Li, Y.J., Fu, Y., Shao, J.H., Luo, L.L., Yang, L., Shi, F.D. & Liu, Y. (2015). Cognitive impairment in Chinese neuromyelitis optica. Multiple Sclerosis, 21 (14), 1839-1846. doi: 10.1177/1352458515576982
Scientific publications (books, monographs, book chapters, proceedings) Cummings, T.J. & Valk, P. van der (2015). Optic Nerve. In Eye Pathology (pp. 233-246). Mizee, M.R., Doorn, R.P. van, Prat, A. & Vries, H.E. de (2015). Blood-brain barrier disruption in multiple sclerosis. In K. Dorovini-Zis (Ed.), The Blood-Brain Barrier in Health and Disease, Volume Two: Pathophysiology and Pathology Ch. 1 (pp. 1, 1-22). Boca Raton, London, New York: CRC Press.
Professional publications Alleman, T. & Oosten, B.W. van (2015). Multipele sclerose in de huisartsenpraktijk. Huisarts en Wetenschap, 58 (5), 258-263. doi: 10.1007/s12445-015-0137-y Meijer, K.A., Schoonheim, M.M. & Geurts, J.J.G. (2015). Cognitieve stoornissen bij multiple sclerose patiĂŤnten verklaard vanuit een netwerkperspectief. Neuropraxis, 19 (2), 31-38. doi: 10.1007/s12474-015-0077-0
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Publications for the general public Geurts, J.J.G. & Hulst, H.E. (2015). Cognitie. Zeist: Regalis. Geurts, J.J.G. & Gaag, H. van der (2015). Het zingende paard. Amsterdam: Prometheus Bert Bakker.
Inaugural lecture Groot, V. de (2015). Gericht aan de slag (19-03-2015). Amsterdam: Vrije Universiteit.
Neurobiology in Mental Health Theses VU/VUmc PhD-student at VU (A) Bloemendaal, L. van (2015, Augustus 25). GLP-1 and the neuroendocrine control of feeding in obesity and type 2 diabetes: food for thought. Vrije Universiteit. Prom./coprom.: prof. dr. M.L. Drent, dr. R.G. IJzerman & prof. dr. D.J. Veltman. Nivard, M.G. (2015, Oktober 01). Developmental genetics of psychopathology. VU University. Prom./coprom.: prof. dr. D.I. Boomsma, dr. C.V. Dolan & dr. C.M. Middeldorp. Vriend, C. (2015, April 29). (Dis)Inhibition Imaging Neuropsychiatry in Parkinson's disease. VU University. Prom./coprom.: prof. dr. H.W. Berendse, prof. dr. J.H. Smit, dr. O.A. van den Heuvel & dr. Y.D. van der Werf.
Theses external PhD-student at VU (B) Koch, H. (2015, November 23). Modulation and Plasticity of Rhythm-Generating Networks. VU Vrije Universiteit (115 pag.). Prom./coprom.: prof. dr. H.D. Mansvelder & Dr. J.M. Ramirez.
Theses VU/VUmc PhD-student at other university (C) Mous, S.E. (2015, September 01). The Distracted Brain. The neurobiology and neuropsychology of attention-deficit/hyperactivity problems in the general population. Erasmus Universiteit Rotterdam (191 pag.). Prom./coprom.: H. Tiemeier, A. van der Lugt & prof. dr. D. Posthuma.
Scientific papers refereed Abdellaoui, A., Ehli, E.A., Hottenga, J.J., Weber, Z., Mbarek, H., Willemsen, G., Beijsterveldt, C.E.M. van, Brooks, A., Hudziak, J.J., Sullivan, P.F., Geus, E.J.C. de, Davies, G.E. & Boomsma, D.I. (2015). CNV Concordance in 1,097 MZ Twin Pairs. Twin Research and Human Genetics, 18 (1), 1-12. doi: 10.1017/thg.2014.86 Abdellaoui, A., Hottenga, J.J., Willemsen, G., Bartels, M., Beijsterveldt, C.E.M. van, Ehli, E.A., Davies, G.E., Brooks, A., Sullivan, P.F., Penninx, B.W.J.H., Geus, E.J.C. de & Boomsma, D.I. (2015). Educational Attainment Influences Levels of Homozygosity through Migration and Assortative Mating. PLoS One, 10 (3):e0118935. doi: 10.1371/journal.pone.0118935 Ai, H., Opmeer, E.M., Veltman, D.J., Wee, N.J. van der, Buchem, M.A. van, Aleman, A. & Tol, M.J. van (2015). Brain activation during emotional memory processing associated with subsequent course of depression. Neuropsychopharmacology, 40 (10), 2454-2463. doi: 10.1038/npp.2015.96 Arloth, J., Bogdan, R., Weber, P., Frishman, G., Menke, A., Wagner, K.V., Balsevich, G., Schmidt, M.V., Karbalai, N., Czamara, D., Altmann, A., Tr端mbach, D., Wurst, W., Mehta, D., Uhr, M., Klengel, T., Erhardt, A., Carey, C.E., Drabant Conley, E., Boomsma, D.I., Penninx, B.W.J.H., Geus, E.J.C. de, Hottenga, J.J., Middeldorp, C.M., Willemsen, G., Smit, J.H., Ruepp, A., M端ller-Myhsok, B., Hariri, A.
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& Binder, E.B. (2015). Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron, 86, 1189-1202. doi: 10.1016/j.neuron.2015.05.034 Aten, J.J., Oudega, M., Exel, E. van, Stek, M.L. & Waarde, J.A. van (2015). Repeated dose titration versus age-based method in electroconvulsive therapy: a pilot study. European Archives of Psychiatry and Clinical Neuroscience, 265 (4), 351-356. doi: 10.1007/s00406-015-0591-3 Barker, J.M., Taylor, J.R., Vries, T.J. de & Peters, J. (2015). Brain-derived neurotrophic factor and addiction: Pathological versus therapeutic effects on drug seeking. Brain Research, 1628, 68-81. doi: 10.1016/j.brainres.2014.10.058 Bartels, M. (2015). Genetics of Wellbeing and Its Components Satisfaction with Life, Happiness, and Quality of Life: A Review and Meta-analysis of Heritability Studies. Behavior Genetics, 45 (2), 137156. doi: 10.1007/s10519-015-9713-y Baselmans, B.M.L., Dongen, J. van, Nivard, M.G., Lin, B., Rodrigues Zilhao Nogueira, N., Boomsma, D.I. & Bartels, M. (2015). Epigenome-Wide Association Study of Wellbeing. Twin Research and Human Genetics, 18 (6), 710-719. doi: 10.1017/thg.2015.85 Bassetti, C.L., Ferini-Strambi, L., Brown, S., Adamantidis, A., Benedetti, F., Bruni, O., Cajochen, C., DolencGroselj, L., Ferri, R., Gais, S., Huber, R., Khatami, R., Lammers, G.J., Luppi, P.H., Manconi, M., Nissen, C., Nobili, L., Peigneux, P., Pollmacher, T., Randerath, W., Riemann, D., Santamaria, J., Schindler, K., Tafti, M., Someren, E.J.W. van & Wetter, T.C. (2015). Neurology and psychiatry: waking up to opportunities of sleep. State of the art and clinical/research priorities for the next decade. European Journal of Neurology, 22 (10), 1337-1354. doi: 10.1111/ene.12781 Beek, J.H.D.A. van, Lubke, G.H., Moor, M.H.M. de, Willemsen, G., Geus, E.J.C. de, Hottenga, J.J., Walters, R.K., Smit, J.H., Penninx, B.W.J.H. & Boomsma, D.I. (2015). Heritability of liver enzyme levels estimated from genome-wide SNP data. European Journal of Human Genetics, 23 (9), 1223-1228. doi: 10.1038/ejhg.2014.259 Bet, P.M., Penninx, B.W.J.H., Laer, S.D. van, Hoogendijk, W.J.G. & Hugtenburg, J.G. (2015). Current and Remitted Depression and Anxiety Disorders as Risk Factors for Medication Nonadherence. Journal of Clinical Psychiatry, 76 (9), E1114-E1121. doi: 10.4088/JCP.14m09001 Bie, H.M.A. de, Ruiter, M.B. de, Ouwendijk, M., Oostrom, K.J., Wilke, M., Boersma, M., Veltman, D.J. & Delemarre-van de Waal, H.A. (2015). Using fMRI to Investigate Memory in Young Children Born Small for Gestational Age. PLoS One, 10 (7):e0129721. doi: 10.1371/journal.pone.0129721 Bloemendaal, L. van, Veltman, D.J., Kulve, J.S. ten, Groot, P.F.C., Ruhe, H.G., Barkhof, F., Sloan, J.H., Diamant, M. & IJzerman, R.G. (2015). Brain reward-system activation in response to anticipation and consumption of palatable food is altered by glucagon-like peptide-1 receptor activation in humans. Diabetes, Obesity and Metabolism, 17 (9), 878-886. doi: 10.1111/dom.12506 Bloemendaal, L. van, Veltman, D.J., Kulve, J.S. ten, Drent, M.L., Barkhof, F., Diamant, M. & IJzerman, R.G. (2015). Emotional eating is associated with increased brain responses to food-cues and reduced sensitivity to GLP-1 receptor activation. Obesity, 23 (10), 2075-2082. doi: 10.1002/oby.21200 Boccardi, M., Bocchetta, M., Apostolova, L.G., Barnes, J., Bartzokis, G., Corbetta, G., deCarli, C., DeToledoMorrell, L., Firbank, M., Ganzola, R., Gerritsen, L., Henneman, W., Killiany, R.J., Malykhin, N., Pasqualetti, P., Pruessner, J.C., Redolfi, A., Robitaille, N., Soininen, H., Tolomeo, D., Wang, L., Watson, C., Wolf, H, Duvernoy, H., Duchesne, S., Jack, C.R. & Frisoni, G. B. (2015). Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance. Alzheimers & Dementia, 11 (2), 126-138. doi: 10.1016/j.jalz.2014.02.009 Bocchetta, M., Boccardi, M., Ganzola, R., Apostolova, L.G., Preboske, G., Wolf, D., Ferrari, C. & Gerritsen, L. (2015). Harmonized benchmark labels of the hippocampus on magnetic resonance: The EADCADNI project. Alzheimers & Dementia, 11 (2), 151-160. doi: 10.1016/j.jalz.2013.12.019 Broos, N., Loonstra, R., Mourik, Y. van, Schetters, D., Schoffelmeer, A.N.M., Pattij, T. & Vries, T.J. de (2015). Subchronic administration of atomoxetine causes an enduring reduction in contextinduced relapse to cocaine seeking without affecting impulsive decision making. Addiction Biology, 20 (4), 714-723. doi: 10.1111/adb.12168 Boomsma, D.I. (2015). Aggression in children: unravelling the interplay of genes and environment through (epi)genetics and metabolomics. Journal of Pediatric and Neonatal Individualized Medicine, 4 (2), e040251. doi: 10.7363/040251
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Bootsman, F., Brouwer, R.M., Kemner, S.M., Schnack, H.G., Schot, A.C. van der, Vonk, R., Hillegers, M.H.J., Boomsma, D.I., Hulshoff Pol, H.E., Nolen, W.A., Kahn, R.S. & Haren, N.E.M. van (2015). Contribution of genes and unique environment to cross-sectional and longitudinal measures of subcortical volumes in bipolar disorder. European Neuropsychopharmacology, 25 (12), 2197-2209. doi: 10.1016/j.euroneuro.2015.09.023 Bot, M., Chan, M.K., Jansen, R., Lamers, F., Vogelzangs, N., Steiner, J., Leweke, F.M., Rothermundt, M., Cooper, J., Bahn, S. & Penninx, B.W.J.H. (2015). Serum proteomic profiling of major depressive disorder. Translational Psychiatry, 5, e599-e599. doi: 10.1038/tp.2015.88 Brouwer, A., Raalte, D.H. van, Diamant, M., Rutters, F., Someren, E.J.W. van, Snoek, F.J., Beekman, A.T.F. & Bremmer, M.A. (2015). Light therapy for better mood and insulin sensitivity in patients with major depression and type 2 diabetes: a randomised, double-blind, parallel-arm trial. BMC Psychiatry, 15:169. doi: 10.1186/s12888-015-0543-5 Brouwer, R.M., Koenis, M.M.G., Schnack, H.G., Baal, G.C.M. van, Soelen, I.L.C. van, Boomsma, D.I. & Hulshoff Pol, H.E. (2015). Longitudinal Development of Hormone Levels and Grey Matter Density in 9 and 12-Year-Old Twins. Behavior Genetics, 45 (3), 313-323. doi: 10.1007/s10519-015-9708-8 Burk, G.F. van, Bartels, M. & Boomsma, D.I. (2015). A Twin-Sibling Study on Early Growth and Hormone Levels in Adolescents. Behavior Genetics, 45 (3), 283-293. doi: 10.1007/s10519-014-9697-z Bus, B.A.A., Molendijk, M.L., Tendolkar, I., Penninx, B.W.J.H., Prickaerts, J., Elzinga, B.M. & Voshaar, R.C.O. (2015). Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time. Molecular Psychiatry, 20 (5), 602-608. doi: 10.1038/mp.2014.83 Busscher, B., Spinhoven, P. & Geus, E.J.C. de (2015). Psychological Distress and Physiological Reactivity During In Vivo Exposure in People With Aviophobia. Psychosomatic Medicine, 77 (7), 762-774. doi: 10.1097/PSY.0000000000000209 Byrne, E.M., Boomsma, D.I., Martin, N.G., Penninx, B.W.J.H., Geus, E.J.C. de, Hoogendijk, W.J.G., Hottenga, J.J., Middeldorp, C.M., Nyholt, DR, Smit, J.H., Oord, E.J. van den, Grootheest, G., Willemsen, G., Zitman, F.G., Neale, B.M., Sullivan, P.F., Raheja, U.K., Stephens, S.H., Heath, A.C., Madden, P.A.F., Vaswani, D., Nijjar, G.V., Ryan, K.A., Youssufi, H., Gehrman, P.R., Shuldiner, A.R., Montgomery, G.W., Wray, N.R., Nelson, E.C., Mitchell, B.D. & Postolache, T.T. (2015). Seasonality shows evidence for polygenic architecture and genetic correlation with schizophrenia and bipolar disorder. Journal of Clinical Psychiatry, 76 (2), 128-134. doi: 10.4088/JCP.14m08981 Cacioppo, J.T., Cacioppo, S., Cole, S.W., Capitanio, J.P., Goossens, L. & Boomsma, D.I. (2015). Loneliness Across Phylogeny and a Call for Comparative Studies and Animal Models. Perspectives on Psychological Science, 10 (2), 202-212. doi: 10.1177/1745691614564876 Carlson, J.O.E., Gatz, M., Pedersen, N.L., Graff, C., Nennesmo, I., Lindstrom, A.K. & Gerritsen, L. (2015). Antemortem Prediction of Braak Stage. Journal of Neuropathology and Experimental Neurology, 74 (11), 1061-1070. doi: 10.1097/NEN.0000000000000251 Chalavi, S., Vissia, E.M., Giesen, M.E., Nijenhuis, E.R.S., Draijer, N., Cole, J.H., Dazzan, P., Pariante, C.M., Madsen, S.K., Rajagopalan, P., Thompson, P.M., Toga, A.W., Veltman, D.J. & Reinders, A.A.T.S (2015). Abnormal Hippocampal Morphology in Dissociative Identity Disorder and Post-Traumatic Stress Disorder Correlates with Childhood Trauma and Dissociative Symptoms. Human Brain Mapping, 36 (5), 1692-1704. doi: 10.1002/hbm.22730 Chalavi, S., Vissia, E.M., Giesen, M.E., Nijenhuis, E.R.S., Draijer, N., Barker, G.J., Veltman, D.J. & Reinders, A.A.T.S (2015). Similar cortical but not subcortical gray matter abnormalities in women with posttraumatic stress disorder with versus without dissociative identity disorder. Psychiatry Research: Neuroimaging, 231 (3), 308-319. doi: 10.1010/j.pccychrcsns.2015.01.014 Cohn, M.D., Pape, L.E., Schmaal, L., Brink, W. van den, Wingen, G. van, Vermeiren, R.R.J.M., Doreleijers, T.A.H., Veltman, D.J. & Popma, A. (2015). Differential Relations Between Juvenile Psychopathic Traits and Resting State Network Connectivity. Human Brain Mapping, 36 (6), 2396-2405. doi: 10.1002/hbm.22779 Cohn, M.D., Veltman, D.J., Pape, L.E., Lith, K. van, Vermeiren, R.R.J.M., Brink, W. van den, Doreleijers, T.A.H. & Popma, A. (2015). Incentive Processing in Persistent Disruptive Behavior and Psychopathic Traits: A Functional Magnetic Resonance Imaging Study in Adolescents. Biological Psychiatry, 78 (9), 615-624. doi: 10.1016/j.biopsych.2014.08.017
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Cornelis, M.C., Byrne, E.M., Esko, T., Nalls, M.A., Ganna, A., Paynter, N., Monda, K.L., Amin, N., Fischer, K., Renstrom, F., Ngwa, J.S., Huikari, V., Cavadino, A., Nolte, I.M., Teumer, A., Yu, K., Marques-Vidal, P., Rawal, R., Manichaikul, A., Wojczynski, M.K., Vink, J.M., Zhao, J.H., Burlutsky, G., Lahti, J., Mikkilä, V., Lemaitre, R.N., Eriksson, J., Musani, S.K., Tanaka, T., Geller, F., Luan, J., Hui, J., Mägi, R., Dimitriou, M., Garcia, M.E., Ho, WrightW.K., Wright, M.J., Rose, L.M., Magnusson, P.K.E., Pedersen, N.L., Couper, D., Oostra, B.A., Hofman, A., Ikram, M.A., Tiemeier, H., Uitterlinden, A.G., Rooij, F.J.A. van, Barroso, I., Johansson, I., Xue, L., Kaakinen, M., Milani, L., Power, C., Snieder, H., Stolk, R.P., Baumeister, S.E., Biffar, R., Gu, F., Bastardot, F., Kutalik, Z., Jacobs, D.R., Forouhi, N.G., Mihailov, E., Lind, L., Lindgren, C., Michaëlsson, K., Morris, A., Jensen, M., Khaw, K.T., Luben, R.N., Wang, J.J., Männisto, S., Perälä, M.M., Kähönen, M., Lehtimäki, T., Viikari, J., Mozaffarian, D., Mukamal, K., Psaty, B.M., Döring, A., Heath, A.C., Montgomery, G.W., Dahmen, N., Carithers, T., Tucker, K.L., Ferrucci, L., Boyd, H.A., Melbye, M., Treur, J.L., Mellström, D., Hottenga, J.J., Prokopenko, I., Tönjes, A., Deloukas, P., Kanoni, S., Lorentzon, M., Houston, D.K., Liu, Y., Danesh, J., Rasheed, A., Mason, M.A., Zonderman, A.B., Franke, L., Kristal, B.S., Karjalainen, J., Reed, D.R., Westra, H.J., Evans, M.K., Saleheen, D., Harris, T.B., Dedoussis, G., Curhan, G., Stumvoll, M., Beilby, J., Pasquale, L.R., Feenstra, B., Bandinelli, S., Ordovas, J.M., Chan, A.T., Peters, U., Ohlsson, C., Gieger, C., Martin, N.G., Waldenberger, M., Siscovick, D.S., Raitakari, O., Eriksson, J.G., Mitchell, P., Hunter, D.J., Kraft, P., Rimm, E.B., Boomsma, D.I., Borecki, I.B., Loos, R.J.F., Wareham, N.J., Vollenweider, P., Caporaso, N., Grabe, H.J., Neuhouser, M.L., Wolffenbuttel, B.H.R., Hu, F.B., Hyppönen, E., Järvelin, M.R., Cupples, L.A., Franks, P.W., Ridker, P.M., Duijn, C.M. van, Heiss, G., Metspalu, A., North, K.E., Ingelsson, E., Nettleton, J.A., Dam, R.M. van & Chasman, D.I. (2015). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry, 20 (5), 647-656. doi: 10.1038/mp.2014.107 Davies, M.N., Verdi, S., Burri, A., Trzaskowski, M., Lee, M.Y., Hettema, J.M., Jansen, R., Boomsma, D.I. & Spector, T.D. (2015). Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression. PLoS One, 10 (8):e0134865. doi: 10.1371/journal.pone.0134865 Day, F.R., Ruth, K.S., Thompson, D.J., Lunetta, K.L., Pervjakova, N., Chasman, D.I., Stolk, L., Finucane, H.K., Sulem, P., Bulik-Sullivan, B.K., Esko, T., Johnson, A.D., Elks, C.E., Franceschini, N., He, C., Altmaier, E., Brody, J.A., Franke, L.L., Huffman, J.E., Keller, M.F., McArdle, P.F., Nutile, T., Porcu, E., Robino, A., Rose, L.M., Schick, U.M., Smith, J.A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J.J., Mangino, M., Smith, A.V., Tanaka, T., Abecasis, G.R., Andrulis, I.L., Anton-Culver, H., Antoniou, A.C., Arndt, V., Arnold, A.M., Barbieri, C., Beckmann, M.W., Beeghly-Fadiel, A., Benitez, J., Bernstein, L., Bielinski, S.J., Blomqvist, C., Boerwinkle, E., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Borresen-Dale, A.L., Boutin, T.S., Brauch, H., Brenner, H., Brüning, T., Burwinkel, B., Campbell, A., Campbell, H., Chanock, S.J., Chapman, J.R., Ida Chen, Y.D., Chenevix-Trench, G., Couch, F.J., Coviello, A.D., Cox, A., Czene, K., Darabi, H., De Vivo, I., Demerath, E.W., Dennis, J., Devilee, P., Dörk, T., dos-Santos-Silva, I., Dunning, A.M., Eicher, J.D., Fasching, P.A., Faul, J.D., Figueroa, J., Flesch-Janys, D., Gandin, I., Garcia, M.E., García-Closas, M., Giles, G.G., Girotto, G.G., Goldberg, M.S., González-Neira, A., Goodarzi, M.O., Grove, M.L., Gudbjartsson, D.F., Guénel, P., Guo, X., Haiman, C.A., Hall, P., Hamann, U., Henderson, B.E., Hocking, L.J., Hofman, A., Homuth, G., Hooning, M.J., Hopper, J.L., Hu, F.B., Huang, J., Humphreys, K., Hunter, D.J., Jakubowska, A., Jones, S.E., Kabisch, M., Karasik, D., Knight, J.A., Kolcic, I., Kooperberg, C., Kosma, V.M., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X., Lindström, S., Liu, Y., Luan, J., Lubinski, J., Mägi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J., Martin, N.G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Müller-Nurasyid, M., Nalls, M., Neale, B.M., Nevanlinna, H., Neven, P., Newman, A.B., Nordestgaard, B.G., Olson, J.E., Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P.D.P., Pirastu, N.N., Pirie, A., Pistis, G., Polasek, O., Porteous, D., Psaty, B.M., Pylkäs, K., Radice, P., Raffel, L.J., Rivadeneira, F., Rudan, I., Rudolph, A., Ruggiero, D., Sala, C.F., Sanna, S., Sawyer, E.J., Schlessinger, D., Schmidt, M.K., Schmidt, F., Schmutzler, R.K., Schoemaker, M.J., Scott, R.A., Seynaeve, C.M., Simard, J., Sorice, R., Southey, M.C., Stöckl, D., Strauch, K., Swerdlow, A., Taylor, K.D., Thorsteinsdottir, U., Toland, A.E., Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S.T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G., Wilson, J.F., Winqvist, R., Wolffenbuttel,
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B.H.R., Wright, A.F., Yannoukakos, D., Zemunik, T., Zheng, W., Zygmunt, M., Bergmann, S., Boomsma, D.I., Buring, J.E., Ferrucci, L., Montgomery, G.W., Gudnason, V., Spector, T.D., Duijn, C.M. van, Alizadeh, BZ, Ciullo, M., Crisponi, L., Easton, D.F., Gasparini, P.P., Gieger, C., Harris, T.B., Hayward, C., Kardia, S.L.R., Kraft, P., McKnight, B., Metspalu, A., Morrison, A.C., Reiner, A.P., Ridker, P.M., Rotter, J.I., Toniolo, D., Uitterlinden, A.G., Ulivi, S., Vรถlzke, H., Wareham, N.J., Weir, D.R., Yerges-Armstrong, L.M., Price, A.L., Stefansson, K., Visser, J.A., Ong, K.K., Chang-Claude, J., Murabito, J.M.M., Perry, J.R.B. & Murray, A. (2015). Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics, 47 (11), 1294-1303. doi: 10.1038/ng.3412 Day, F.R., Ruth, K.S., Thompson, D.J., Lunetta, K.L., Pervjakova, N., Chasman, D.I., Stolk, L., Finucane, H.K., Sulem, P., Bulik-Sullivan, B., Esko, T., Johnson, A.D., Elks, C.E., Franceschini, N., He, C., Altmaier, E., Brody, J.A., Franke, L.L., Huffman, J.E., Keller, M.F., McArdle, P.F., Nutile, T., Porcu, E., Robino, A., Rose, L.M., Schick, U.M., Smith, J.A., Teumer, A., Traglia, M., Vuckovic, D., Yao, J., Zhao, W., Albrecht, E., Amin, N., Corre, T., Hottenga, J., Mangino, M., Smith, A.V., Tanaka, T., Abecasis, G.R., Andrulis, I.L., Anton-Culver, H., Antoniou, A.C., Arndt, V., Arnold, A.M., Barbieri, C., Beckmann, M.W., Beeghly-Fadiel, A., Benitez, J., Bernstein, L., Bielinski, S.J., Blomqvist, C., Boerwinkle, E., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Borresen-Dale, A., Boutin, T.S., Brauch, H., Brenner, H., Bruening, T., Burwinkel, B., Campbell, A., Campbell, H., Chanock, S.J., Chapman, J.R., Chen, Y.I., Chenevix-Trench, G., Couch, F.J., Coviello, A.D., Cox, A., Czene, K., Darabi, H., Vivo, I. De, Demerath, E.W., Dennis, J., Devilee, P., Doerk, T., dos-Santos-Silva, I., Dunning, A.M., Eicher, J.D., Fasching, P.A., Faul, J.D., Figueroa, J., Flesch-Janys, D., Gandin, I., Garcia, M.E., Garcia-Closas, M., Giles, G.G., Girotto, G.G., Goldberg, M.S., Gonzalez-Neira, A., Goodarzi, M.O., Grove, M.L., Gudbjartsson, D.F., Guenel, P., Guo, X., Haiman, C.A., Hall, P., Hamann, U., Henderson, B.E., Hocking, L.J., Hofman, A., Homuth, G., Hooning, M.J., Hopper, J.L., Hu, F.B., Huang, J., Humphreys, K., Hunter, D.J., Jakubowska, A., Jones, S.E., Kabisch, M., Karasik, D., Knight, J.A., Kolcic, I., Kooperberg, C., Kosma, V., Kriebel, J., Kristensen, V., Lambrechts, D., Langenberg, C., Li, J., Li, X., Lindstroem, S., Liu, Y., Luan, J., Lubinski, J., Maegi, R., Mannermaa, A., Manz, J., Margolin, S., Marten, J., Martin, N.G., Masciullo, C., Meindl, A., Michailidou, K., Mihailov, E., Milani, L., Milne, R.L., Mueller-Nurasyid, M., Nalls, M., Neale, B.M., Nevanlinna, H., Neven, P., Newman, A.B., Nordestgaard, B.G., Olson, J.E., Padmanabhan, S., Peterlongo, P., Peters, U., Petersmann, A., Peto, J., Pharoah, P.D.P., Pirastu, N.N., Pirie, A., Pistis, G., Polasek, O., Porteous, D., Psaty, B.M., Pylkaes, K., Radice, P., Raffel, L.J., Rivadeneira, F., Rudan, I., Rudolph, A., Ruggiero, D., Sala, C.F., Sanna, S., Sawyer, E.J., Schlessinger, D., Schmidt, M.K., Schmidt, F., Schmutzler, R.K., Schoemaker, M.J., Scott, R.A., Seynaeve, C.M., Simard, J., Sorice, R., Southey, M.C., Stoeckl, D., Strauch, K., Swerdlow, A., Taylor, K.D., Thorsteinsdottir, U., Toland, A.E., Tomlinson, I., Truong, T., Tryggvadottir, L., Turner, S.T., Vozzi, D., Wang, Q., Wellons, M., Willemsen, G., Wilson, J.F., Winqvist, R., Wolffenbuttel, B.B.H.R., Wright, A.F., Yannoukakos, D., Zemunik, T., Zheng, W., Zygmunt, M., Bergmann, S., Boomsma, D.I., Buring, J.E., Ferrucci, L., Montgomery, G.W., Gudnason, V., Spector, T.D., Duijn, C.M. van, Alizadeh, BZ, Ciullo, M., Crisponi, L., Easton, D.F., Gasparini, P.P., Gieger, C., Harris, T.B., Hayward, C., Kardia, S.L.R., Kraft, P., McKnight, B., Metspalu, A., Morrison, A.C., Reiner, A.P., Ridker, P.M., Rotter, J.I., Toniolo, D., Uitterlinden, A. G., Ulivi, S., Voelzke, H., Wareham, N.J., Weir, D.R., Yerges-Armstrong, L.M., Price, A.L., Stefansson, K., Visser, J.A., Ong, K.K., Chang-Claude, J., Murabito, J.M., Perry, J.R.B. & Murray, A. (2015). Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair. Obstetrical and Gynecological Survey, 70 (12), 758-762. doi: 10.1097/01.ogx.0000473766.71624.99 Dekker, K., Benjamins, J.S., Straten, A. van, Hofman, W.F. & Someren, E.J.W. van (2015). Effectiveness of internet-supported cognitive behavioral and chronobiological interventions and effect moderation by insomnia subtype: study protocol of a randomized controlled trial. Trials, 2015:292. doi: 10.1186/s13063-015-0790-2 Dilekoz, E., Houben, T., Eikermann-Hearter, K., Balkaya, M., Lenselink, A.M., Whalen, M.J., Spijker, S., Ferrari, M.D., Maagdenberg, A.M.J.M. van den & Ayate, C. (2015). Migraine mutations impair hippocampal learning despite enhanced long-term potentiation. Journal of Neuroscience, 35 (8), 3397-3402. doi: 10.1523/JNEUROSCI.2630-14.2015
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Dolan, C.V., Nivard, M.G., Dongen, J. van, Sluis, S. van der & Boomsma, D.I. (2015). Methylation as an epigenetic source of random genetic effects in the classical twin design. Advances in Genomics and Genetics, 5, 305-315. doi: 10.2147/AGG.S46909 Dongen, J. van, Nivard, M.G., Baselmans, B.M.L., Rodrigues Zilhao Nogueira, N., Ligthart, R.S.L., Heijmans, B.T., Bartels, M. & Boomsma, D.I. (2015). Epigenome-Wide Association Study of Aggressive Behavior. Twin Research and Human Genetics, 18 (6), 686-698. doi: 10.1017/thg.2015.74 Dongen, J. van, Willemsen, G., Heijmans, B.T., Neuteboom, J., Kluft, C., Jansen, R., Penninx, B.W.J.H., Slagboom, P.E., Geus, E.J.C. de & Boomsma, D.I. (2015). Longitudinal weight differences, gene expression and blood biomarkers in BMI-discordant identical twins. International Journal of Obesity, 39 (6), 899-909. doi: 10.1038/ijo.2015.24 Draisma, H.H.M., Pool, R., Kobl, M., Jansen, R., Petersen, A.K., Vaarhorst, A.A.M., Yet, I., Haller, T., Demirkan, A., Esko, T., Zhu, G., Böhringer, S., Beekman, M., Klinken, J.B. van, Römisch-Margl, W., Prehn, C., Adamski, J., Craen, A.J. de, Leeuwen, E.M. van, Amin, N., Dharuri, H., Westra, H.J., Franke, L., Geus, E.J.C. de, Hottenga, J.J., Willemsen, G., Henders, A.K., Montgomery, G.W., Nyholt, DR, Whitfield, J.B., Penninx, B.W.J.H., Spector, T.D., Metspalu, A., Slagboom, P.E., Willems van Dijk, K., Hoen, P.A.C. 't, Strauch, K., Martin, N.G., Ommen, G.J.B van, Illig, T., Bell, J.T., Mangino, M., Suhre, K., McCarthy, M.I., Gieger, C., Isaacs, A., Duijn, C.M. van & Boomsma, D.I. (2015). Genomewide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications, 6, 7208. doi: 10.1038/ncomms8208 Duivis, H.E., Kupper, N., Vermunt, J.K., Penninx, B.W., Bosch, N.M., Riese, H., Oldehinkel, A.J. & Jonge, P. de (2015). Depression Trajectories, Inflammation, and Lifestyle Factors in Adolescence: The TRacking Adolescents' Individual Lives Survey. Health Psychology, 34 (11), 1047-1057. doi: 10.1037/hea0000210 Fall, T., Hägg, S., Ploner, A., Mägi, R., Fischer, K., Draisma, H.H.M., Sarin, A.-P., Benyamin, B., Ladenvall, C., Akerlund, M., Kals, M., Esko, T., Nelson, C.P., Kaakinen, M., Huikari, V., Mangino, M., Meirhaeghe, A., Kristiansson, K., Nuotio, M.L., Kobl, M., Grallert, H., Dehghan, A., Kuningas, M., Vries, P.S. de, Bruijn, R.F.A.G. de, Willems, S.M., Heikkilä, K., Silventoinen, K., Pietilainen, K.H., Legry, V., Giedraitis, V., Goumidi, L., Syvänen, A.C., Strauch, K., Koenig, W., Lichtner, P., Herder, C., Palotie, A., Menni, C., Uitterlinden, A.G., Kuulasmaa, K., Havulinna, A.S., Moreno, L.A., Gonzalez-Gross, M., Evans, A., Tregouet, D.A., Yarnell, J.W., Virtamo, J., Ferrières, J., Veronesi, G., Perola, M., Arveiler, D., Brambilla, P., Lind, L., Kaprio, J., Hofman, A., Stricker, B.H., Duijn, C.M. van, Arfan Ikram, M., Franco, O.H., Cottel, D., Dallongeville, J., Hall, A.S., Jula, A., Tobin, M.D., Penninx, B.W.J.H., Peters, A., Gieger, C., Samani, N.J., Montgomery, G.W., Whitfield, J.B., Martin, N.G., Groop, L., Spector, T.D., Magnusson, P.K., Amouyel, P., Boomsma, D.I., Nilsson, P.M., Järvelin, M.R., Lyssenko, V., Metspalu, A., Strachan, D.P., Salomaa, V., Ripatti, S., Pedersen, N.L., Prokopenko, I., McCarthy, M.I. & Ingelsson, E. (2015). Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors. Diabetes, 64 (5), 1841-1852. doi: 10.2337/db14-0988 Fedko, I.O., Hottenga, J.J., Medina-Gomez, C., Pappa, I., Beijsterveldt, C.E.M. van, Ehli, E.A., Davies, G.E., Rivadeneira, F., Tiemeier, H., Swertz, M.A., Middeldorp, C.M., Bartels, M. & Boomsma, D.I. (2015). Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height. Behavior Genetics, 45 (5), 514-528. doi: 10.1007/s10519-015-9725-7 Ferencz, B. & Gerritsen, L. (2015). Genetics and Underlying Pathology of Dementia. Neuropsychology Review, 25 (1), 113-124. doi: 10.1007/s11065-014-9276-3 Finkenauer, C., Buyukcan-Tetik, A., Baumeister, R. F., Schoemaker, K., Bartels, M. & Vohs, K. D. (2015). Out of control: Identifying the role of self-control strength in family violence. Current Directions in Psychological Science, 24 (4), 261-266. doi: 10.1177/0963721415570730 Francioli, L.C., Polak, P.P., Koren, A., Menelaou, A., Chun, S., Renkens, I., Duijn, C.M. van, Swertz, M.A., Wijmenga, C., Ommen, G.J. van, Slagboom, P.E., Boomsma, D.I., Ye, K., Guryev, V., Arndt, P.F., Kloosterman, W.P., Bakker, P.I.W., Sunyaev, S.R., Dijk, F., Neerincx, P.B.T., Pulit, S.L., Deelen, P., Elbers, C.C., Palamara, P.F., Pe'er, I., Abdellaoui, A., Oven, M. van, Vermaat, M., Li, M., Laros, J.F.J., Stoneking, M., Knijff, P. de, Kayser, M., Veldink, J.H., Berg, L.H. Van den, Byelas, H., Dunnen, J.T. den, Dijkstra, M., Amin, N., Velde, K.J. van der, Hottenga, J.J., Setten, J. van, Leeuwen, E.M. van, Kanterakis, A., Kattenberg, V.M., Karssen, L.C., Schaik, B.D.C. van, Bot, J., Nijman, I.J., Enckevort, D. van, Mei, H., Koval, V., Estrada, K., Medina-Gomez, C., Lameijer, E.W., Moed, M.H., Hehir-Kwa, J.Y.,
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E.B., Wentworth-Shields, W., Whitfield, J.B., Wild, S., Willemsen, G., Yajnik, C.S., Yao, J., Zaza, G., Zhu, X., Salem, R.M., Melbye, M., Bisgaard, H., Samani, N.J., Cusi, D., Mackey, D.A., Cooper, R.S., Froguel, P., Pasterkamp, G., Grant, S.F.A., Hakonarson, H., Ferrucci, L., Scott, R.A., Morris, A.D., Palmer, C.N.A., Dedoussis, G., Deloukas, P., Bertram, L., Lindenberger, U., Berndt, S.I., Lindgren, C.M., Timpson, N.J., Tönjes, A., Munroe, P.B., Sorensen, T.I.A., Rotimi, C.N., Arnett, D.K., Oldehinkel, A.J., Kardia, S.L.R., Balkau, B., Gambaro, G., Morris, A.P., Eriksson, J.G., Wright, M.J., Martin, N.G., Hunt, S.C., Starr, J.M., Deary, I.J., Griffiths, L.R., Tiemeier, H., Pirastu, N., Kaprio, J., Wareham, N.J., Pérusse, L., Wilson, J.G., Girotto, G., Caulfield, M.J., Raitakari, O., Boomsma, D.I., Gieger, C., Harst, P. van der, Hicks, A.A., Kraft, P., Sinisalo, J., Knekt, P., Johannesson, M., Magnusson, P.K.E., Hamsten, A., Schmidt, R., Borecki, I.B., Vartiainen, E., Becker, D.M., Bharadwaj, D., Mohlke, K.L., Boehnke, M., Duijn, C.M. van, Sanghera, D.K., Teumer, A., Zeggini, E., Metspalu, A., Gasparini, P., Ulivi, S., Ober, C., Toniolo, D., Rudan, I., Porteous, D.J., Ciullo, M., Spector, T.D., Hayward, C., Dupuis, J., Loos, R.J.F., Wright, A.F., Chandak, G.R., Vollenweider, P., Shuldiner, A.R., Ridker, P.M., Rotter, J.I., Sattar, N., Gyllensten, U., North, K.E., Pirastu, M., Psaty, B.M., Weir, D.R., Laakso, M., Gudnason, V., Takahashi, A., Chambers, J.C., Kooner, J.S., Strachan, D.P., Campbell, H., Hirschhorn, J.N., Perola, M., Polasek, O. & Wilson, J.F. (2015). Directional dominance on stature and cognition in diverse human populations. Nature, 523 (7561), 459-462. doi: 10.1038/nature14618 Kelmemi, W., Teeuw, M.E., Bochdanovits, Z., Ouburg, S., Jonker, M.A., Alkuraya, F., Hashem, M., Kayserili, H., Haeringen, A. van, Sheridan, E., Masri, A., Cobben, J.M., Rizzu, P., Kostense, P.J., Dommering, C.J., Henneman, L., Bouhamed-Chaabouni, H., Heutink, P., Kate, L.P. ten & Cornel, M.C. (2015). Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome. BMC Medical Genetics, 16:50. doi: 10.1186/s12881-015-0191-0 Kendler, K.S., Aggen, S.H., Li, Y., Lewis, C.M., Breen, G., Boomsma, D.I., Bot, M., Penninx, B.W.J.H. & Flint, J. (2015). The similarity of the structure of DSM-IV criteria for major depression in depressed women from China, the United States and Europe. Psychological Medicine, 45 (09), 1945-1954. doi: 10.1017/S0033291714003067 Kloosterman, W.P., Francioli, L.C., Hormozdiari, F., Marschall, T., Hehir-Kwa, J.Y., Abdellaoui, A., Lameijer, E.W., Moed, M.H., Koval, V., Renkens, I., Roosmalen, M.J. van, Arp, P., Karssen, L.C., Coe, B.P., Handsaker, R.E., Suchiman, H.E.D., Cuppen, E., Tjwan Thung, D., McVey, M., Wendl, M.C., Uitterlinden, A.G., Duijn, C.M. van, Swertz, M.A., Wijmenga, C., Ommen, G.J.B van, Slagboom, P.E., Boomsma, D.I., Schönhuth, A., Eichler, E.E., Bakker, P.I.W., Ye, K. & Guryev, V. (2015). Characteristics of de novo structural changes in the human genome. Genome Research, 25 (6), 792-801. doi: 10.1101/gr.185041.114 Klumpers, U.M.H., Veltman, D.J., Tol, M.J. van, Kloet, R.W., Boellaard, R., Lammertsma, A.A. & Hoogendijk, W.J.G. (2015). Neurophysiological Effects of Sleep Deprivation in Healthy Adults, a Pilot Study. PLoS One, 10 (1):e0116906. doi: 10.1371/journal.pone.0116906 Kochunov, P., Jahanshad, N., Marcus, D., Winkler, A., Sprooten, E., Nichols, T.E., Wright, S.N., Hong, L.E., Patel, B., Behrens, T., Jbabdi, S., Andersson, J., Lenglet, C., Yacoub, E., Moeller, S., Auerbach, E., Ugurbil, K., Sotiropoulos, S.N., Brouwer, R.M., Landman, B., Lemaitre, H., Braber, A. den, Zwiers, M.P., Ritchie, S., Hulzen, K.J.E. van, Almasy, L., Curran, J., Zubicaray, G.I. de, Duggirala, R., Fox, P., Martin, N.G., McMahon, K.L., Mitchell, B., Olvera, R.L., Peterson, C., Starr, J., Sussmann, J.E., Wardlaw, J.M., Wright, M., Boomsma, D.I., Kahn, R.S., Geus, E.J.C. de, Williamson, D.E., Hariri, A., Ent, D. van t, Bastin, M.E., McIntosh, A., Deary, I.J., Hulshoff Pol, H.E., Blangero, J., Thompson, P.M., Glahn, D.C. & Essen, D.C. van (2015). Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data. NeuroImage, 111, 300-311. doi: 10.1016/j.neuroimage.2015.02.050 Koellinger, P.D. & Treffers, T. (2015). Joy Leads to Overconfidence, and a Simple Countermeasure. PLoS One, 10 (12):e0143263. doi: 10.1371/journal.pone.0143263 Koenders, L., Machielsen, M.W.J., Meer, FJ van der, Gasselt, A.C.M. van, Meijer, C.J., Brink, W. van den, Koeter, M.W.J., Caan, M.W.A., Cousijn, J., Braber, A. den, Ent, D. van 't, Rive, M.M., Schene, A.H., Giessen, E. van der, Huyser, C., Kwaasteniet, B.P. de, Veltman, D.J. & Haan, L. de (2015). Brain
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Whincup, P.H., Mbarek, H., Geus, E.J.C. de, Vink, J.M., Boomsma, D.I., Davey Smith, G., Lawlor, D.A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J.W., Power, C., HyppÜnen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimaki, M., Smith, B.H., Hayward, C., Sorensen, T.I.A., Thuesen, B.H., Sattar, N., Morris, R.W., Romundstad, P.R., Munafò, M., Jarvelin, M.R. & Husemoen, L.L.N. (2015). Effect of Smoking on Blood Pressure and Resting Heart Rate - A Mendelian Randomization Meta-Analysis in the CARTA Consortium. 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V., Gieger, C., Gottesman, O., Gudnason, V., Gyllensten, U., Hall, A.S., Harris, T.B., Hattersley, A.T., Hicks, A.A., Hindorff, L.A., Hingorani, A.D., Hofman, A., Homuth, G., Hovingh, G.K., Humphries, S.E., Hunt, S.C., Hypponen, E., Illig, T., Jacobs, K.B., Jarvelin, M., Joeckel, K., Johansen, B., Jousilahti, P., Jukema, J.W., Jula, A.M., Kaprio, J., Kastelein, J.J.P., Keinanen-Kiukaanniemi, S.M., Kiemeney, L.A., Knekt, P., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuusisto, J., Lakka, T.A., Langenberg, C., Le Marchand, L., Lehtimaki, T., Lyssenko, V., Mannisto, S., Marette, A., Matise, T.C.,
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McKenzie, C.A., McKnight, B., Moll, F.L., Morris, A.D., Morris, A.P., Murray, J.C., Nelis, M., Ohlsson, C., Oldehinkel, A.J., Ong, K.K., Madden, P.A.F., Pasterkamp, G., Peden, J.F., Peters, A., Postma, D.S., Pramstaller, P.P., Price, J.F., Qi, L., Raitakari, O.T., Rankinen, T., Rao, D.C., Rice, T.K., Ridker, P.M., Rioux, J.D., Ritchie, M.D., Rudan, I., Salomaa, V., Samani, N.J., Saramines, J., Sarzynski, M.A., Schunkert, H., Schwarz, P.E.H., Sever, P., Shuldiner, A.R., Sinisalo, J., Stolk, R.P, Strauch, K., Toenjes, A., Tregouet, D., Tremblay, A., Tremoli, E., Virtamo, J., Vohl, M., Voelker, U., Waeber, G., Willemsen, G., Witteman, J.C., Zillikens, M.C., Adair, L.S., Amouyel, P., Asselbergs, F.W., Assimes, T.L., Bochud, M., Boehm, B.O., Boerwinkle, E., Bornstein, S.R., Bottinger, E.P., Bouchard, C., Cauchi, S., Chambers, J.C., Chanock, S.J., Cooper, R.S., de Bakker, P.I.W., Dedoussis, G., Ferrucci, L., Franks, P.W., Froguel, P., Groop, L.C., Haiman, C.A., Hamsten, A., Hui, J., Hunter, D.J., Hveem, K., Kaplan, R.C., Kivimaki, M., Kuh, D, Laakso, M., Liu, Y., Martin, N.G., Maerz, W., Melbve, M., Metspalu, A., Moebus, S., Munroe, P.B., Njolstad, I., Oostra, B.A., Palmer, C.N.A., Pedersen, N.L., Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T.E., Saleheen, D., Sattar, N., Schadt, E.E., Schlessinger, D., Slagboom, P.E., Snieder, H., Spector, T.D., Thorsteinsdottir, U.R., Stumvoll, M., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., van der Harst, P., Walker, M., Wallaschofski, H., Wareham, N.J., Watkins, H., Weir, D.R., Wichmann, H.-., Wilson, J.F., Zanen, P., Borecki, I.B., Deloukas, P., Fox, C.S., Heid, I.M., O'Connell, J.R., Strachan, D.P., Stefansson, K., van Duijri, C.M., Abecasis, G.R., Franke, L., Frayling, T.M., McCarthy, M.I., Visscher, P. M., Scherag, A., Willer, C.J., Boehnke, M., Mohlke, K.L., Lindgren, C.M., Beckmann, J.S., Barroso, I., North, K.E., Ingelsson, E., Hirschhorn, J.N., Loos, R.J.F. & Speliotes, E.K. (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518 (7538), 197-206. doi: 10.1038/nature14177 Loehlin, J.C., Bartels, M., Boomsma, D.I., Bratko, D., Martin, N.G., Nichols, R.C. & Wright, M.J. (2015). Is There a Genetic Correlation Between General Factors of Intelligence and Personality? Twin Research and Human Genetics, 18 (03), 234-242. doi: 10.1017/thg.2015.28 Lubke, G.H., Ouwens, K.G., Moor, M.H.M. de, Trull, T.J. & Boomsma, D.I. (2015). Population heterogeneity of trait anger and differential associations of trait anger facets with borderline personality features, neuroticism, depression, Attention Deficit Hyperactivity Disorder (ADHD), and alcohol problems. Psychiatry Research, 230 (2), 553-560. doi: 10.1016/j.psychres.2015.10.003 Luik, A.I., Zuurbier, L.A., Direk, N., Hofman, A., Someren, E.J.W. van & Tiemeier, H. (2015). 24-Hour Activity Rhythm and Sleep Disturbances in Depression and Anxiety: A Population-Based Study of Middle-Aged and Older Persons. Depression and Anxiety, 32 (9), 684-692. doi: 10.1002/da.22355 Luik, A.L., Direk, N., Zuurbier, L.A., Hofman, A., Someren, E.J.W. van & Tiemeier, H. (2015). Sleep and 24-h activity rhythms in relation to cortisol change after a very low-dose of dexamethasone. Psychoneuroendocrinology, 53, 207-216. doi: 10.1016/j.psyneuen.2015.01.011 Maier, R., Moser, G., Chen, G.B., Ripke, S., Boomsma, D.I., Geus, E.J.C. de, Hottenga, J.J., Middeldorp, C.M., Posthuma, D., Willemsen, G., Coryell, W.H., Potash, J.B., Scheftner, W.A., Shi, J., Weissmann, M.M., Hultman, C.M., Landén, M., Levinson, D.F., Kendler, K.S., Smoller, J.W., Wray, N.R. & Lee, S.H. (2015). Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder. American Journal of Human Genetics, 96 (2), 283-294. doi: 10.1016/j.ajhg.2014.12.006 Malik, R., Freilinger, T., Winsvold, B.S., Anttila, V., Heiden, J. van der, Traylor, M., Vries, B. de, Holliday, E.G., Terwindt, G.M., Sturm, J., Bis, J.C., Hopewell, J.C., Ferrari, M.D., Rannikmae, K., Wessman, M., Kallela, M., Kubisch, C., Fornage, M., Meschia, J.F., Lehtimäki, T., Sudlow, C., Clarke, R., Chasman, D.I., Mitchell, B.D., Maguire, J., Kaprio, J., Farrall, M., Raitakari, O.T., Kurth, T., Arfan Ikram, M., Reiner, A.P., Longstreth, Jr. W.T., Rothwell, P.M., Strachan, D.P., Sharma, P., Seshadri, S., Quaye, L., Cherkas, L., Schürks, M., Rosand, J., Ligthart, R.S.L., Boncoraglio, G.B., Davey Smith, G., Duijn, C.M. van, Stefansson, K., Worrall, B.B., Nyholt, DR, Markus, H.S., Maagdenberg, A.M.J.M. van den, Cotsapas, C., Zwart, J.A. & Palotie, A. (2015). Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants. Neurology, 84 (21), 2132-2145. doi: 10.1212/WNL.0000000000001606 Marle, H.J.F. van (2015). PTSD as a memory disorder. European Journal of Psychotraumatology, 6, 27633. doi: 10.3402/ejpt.v6.27633
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Martin, H.C., Christ, R., Hussin, J.G., O'Connell, J., Gordon, S., Mbarek, H., Hottenga, J.J., McAloney, K., Willemsen, G., Gasparini, P., Pirastu, N., Montgomery, G.W., Navarro, P., Soranzo, N., Toniolo, D., Vitart, V., Wilson, J.F., Marchini, J., Boomsma, D.I., Martin, N.G. & Donnelly, P. (2015). Multicohort analysis of the maternal age effect on recombination. Nature Communications, 6:7846. doi: 10.1038/ncomms8846 Mavioglu, R.N., Boomsma, D.I. & Bartels, M. (2015). Causes of individual differences in adolescent optimism: a study in Dutch twins and their siblings. European Child and Adolescent Psychiatry, 24 (11), 1381-1388. doi: 10.1007/s00787-015-0680-x Mbarek, H., Milaneschi, Y., Fedko, I.O., Hottenga, J.J., Moor, M.H.M. de, Jansen, R., Gelernter, J., Sherva, R., Willemsen, G., Boomsma, D.I., Penninx, B.W.J.H. & Vink, J.M. (2015). The Genetics of Alcohol Dependence: Twin and SNP-Based Heritability, and Genome-Wide Association Study Based on AUDIT Scores. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 168 (8), 739-748. doi: 10.1002/ajmg.b.32379 Meijden, W.P. van der, Lindert, B.H.W. te, Bijlenga, D., Coppens, J.E., Gomez-Herrero, G., Bruijel, J., Kooij, J.J.S, Cajochen, C., Bourgin, P. & Someren, E.J.W. van (2015). Post-illumination pupil response after blue light: Reliability of optimized melanopsin-based phototransduction assessment. Experimental Eye Research, 139, 73-80. doi: 10.1016/j.exer.2015.07.010 Merjonen, P.J., Dolan, C.V., Bartels, M. & Boomsma, D.I. (2015). Does Breastfeeding Behavior Run in Families? Evidence From Twins, Their Sisters and Their Mothers in the Netherlands. Twin Research and Human Genetics, 18 (2), 179-187. doi: 10.1017/thg.2015.5 Meurs, M. van, Groenewold, N.A., Roest, A.M., Wee, N.J.A. van der, Veltman, D.J., Tol, M.J. van & Jonge, P. de (2015). The associations of depression and hypertension with brain volumes: Independent or interactive? NeuroImage: Clinical, 8, 79-86. doi: 10.1016/j.nicl.2015.03.020 Mihailidis, S., Bockmann, M., McConnell, E., Hughes, T., Beijsterveldt, C.E.M. van, Boomsma, D.I., McMaster, M.T. & Townsend, G. (2015). The Influence of Chorion Type on Health Measures at Birth and Dental Development in Australian and Dutch Twins: A Comparative Study. Twin Research and Human Genetics, 18 (4), 368-374. doi: 10.1017/thg.2015.43 Minica, C.C., Dolan, C.V., Hottenga, J.J., Pool, R., Fedko, I.O., Mbarek, H., Huppertz, C., Bartels, M., Boomsma, D.I. & Vink, J.M. (2015). Heritability, SNP- and Gene-Based Analyses of Cannabis Use Initiation and Age at Onset. Behavior Genetics, 45 (5), 503-513. doi: 10.1007/s10519-015-9723-9 Minica, C.C., Dolan, C.V., Kampert, M.M.D., Boomsma, D.I. & Vink, J.M. (2015). Sandwich corrected standard errors in family-based genome-wide association studies. European Journal of Human Genetics, 23 (3), 388-394. doi: 10.1038/ejhg.2014.94 Molenaar, D., Middeldorp, C.M., Beijsterveldt, C.E.M. van & Boomsma, D.I. (2015). Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype 9 Environment Interaction. Child Development, 86 (6), 1999-2016. doi: 10.1111/cdev.12451 Moor, M.H.M. de, Berg, S.M. van den, Verweij, C.J.H., Krueger, R.F., Luciano, M., Arias-Vasquez, A., Matteson, L.K., Derringer, J., Esko, T., Amin, N., Gordon, S.D., Hansell, N.K., Hart, A.B., Seppälä, I., Huffman, J.E., Konte, B., Lahti, J., Lee, M.Y., Miller, M., Nutile, T., Tanaka, T., Teumer, A., Viktorin, A., Wedenoja, J., Abecasis, G.R., Adkins, D.E., Agrawal, A., Allik, J., Appel, K., Bigdeli, T.B., Busonero, F., Campbell, H., Costa, P.T., Davey Smith, G., Davies, G., Wit, H. de, Ding, J., Engelhardt, B.E., Eriksson, J.G., Fedko, I.O., Ferrucci, L., Franke, B., Giegling, I., Grucza, R., Hartmann, A.M., Heath, A.C., Heinonen, K., Henders, A.K., Homuth, G., Hottenga, J.J., Iacono, W.G., Janzing, J., Jokela, M, Karlsson, R., Kemp, J.P., Kirkpatrick, M.G., Latvala, A., Lehtimäki, T., Liewald, D.C., Madden, P.A.F., Magri, C., Magnusson, P.K.E., Marten, J., Maschio, A., Medland, S.E., Mihailov, E., Milaneschi, Y., Montgomery, G.W., Nauck, M., Ouwens, K.G., Palotie, A., Pettersson, E., Polasek, O., Qian, Y., Pulkki-Råback, L., Raitakari, O.T., Realo, A., Rose, R.J., Ruggiero, D., Schmidt, C.O., Slutske, W.S., Sorice, R., Starr, J.M., St Pourcain, B., Sutin, A.R., Timpson, N.J., Trochet, H., Vermeulen, S., Vuoksimaa, E., Widén, E., Wouda, J., Wright, M.J., Zgaga, L., Porteous, D., Minelli, A., Palmer, A.A., Rujescu, D., Ciullo, M., Hayward, C., Rudan, I., Metspalu, A., Kaprio, J., Deary, I.J., Räikkönen, K., Wilson, J.F., Keltikangas-Järvinen, L., Bierut, L.J., Hettema, J.M., Grabe, H.J., Duijn, C.M. van, Evans, D.M., Schlessinger, D., Pedersen, N.L., Terracciano, A., McGue, M., Penninx, B.W.J.H., Martin, N.G. & Boomsma, D.I. (2015). Meta-analysis of Genome-wide Association Studies for Neuroticism, and
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Modeling linkage disequilibrium increases accuracy of polygenic risk scores. American Journal of Human Genetics, 97, 576-592. doi: 10.1016/j.ajhg.2015.09.001 Vimaleswaran, K.S., Cavadino, A., Verweij, N., Nolte, I.M., Leach, I.M., Auvinen, J., Veijola, J., Elliott, P., Penninx, B.W., Snieder, H., Jarvelin, M.R., Harst, P. van der, Cohen, R.D., Boucher, B.J. & Hypponen, E. (2015). Interactions between uncoupling protein 2 gene polymorphisms, obesity and alcohol intake on liver function: a large meta-analysed population-based study. European Journal of Endocrinology, 173 (6), 863-872. doi: 10.1530/EJE-15-0839 Vinkers, C.H., Joels, M., Milaneschi, Y., Gerritsen, L., Kahn, R. S., Penninx, B.W.J.H. & Boks, M.P.M. (2015). Mineralocorticoid receptor haplotypes sex-dependently moderate depression susceptibility following childhood maltreatment. Psychoneuroendocrinology, 54, 90-102. doi: 10.1016/j.psyneuen.2015.01.018 Willemsen, G., Ward, K.J., Bell, C.G., Christensen, K., Bowden, J., Dalgard, C., Harris, J.R., Kaprio, J., Lyle, R., Magnusson, P.K.E., Mather, K.A., Ordoñana, J.R., Perez-Riquelme, F., Pedersen, N.L., Pietilainen, K.H., Sachdev, P.S., Boomsma, D.I. & Spector, T.D. (2015). The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium. Twin Research and Human Genetics, 18 (6), 762-771. doi: 10.1017/thg.2015.83 Winkler, T.W., Justice, A.E., Graff, M., Barata, L., Feitosa, M.F., Chu, S., Czajkowski, J., Esko, T., Fall, T., Kilpelainen, T.O., Lu, Y., Magi, R., Mihailov, E., Pers, T.H., Rueeger, S., Teumer, A., Ehret, G.B., Ferreira, T., Heard-Costa, N.L., Karjalainen, J., Lagou, V., Mahajan, A., Neinast, M.D., Prokopenko, I., Simino, J., Teslovich, T.M., Jansen, R., Westra, H., White, C.C., Absher, D., Ahluwalia, T.S., Ahmad, S., Albrecht, E., Alves, A.C., Bragg-Gresham, J.L., Craen, A.J.M., Bis, J.C., Bonnefond, A., Boucher, G., Cadby, G., Cheng, Y., Chiang, C.W.K., Delgado, G., Demirkan, A., Dueker, N., Eklund, N., Eiriksdottir, G., Eriksson, J., Feenstra, B., Fischer, K., Frau, F., Galesloot, T.E., Geller, F., Goel, A., Gorski, M., Grammer, T.B., Gustafsson, S., Haitjema, S., Hottenga, J.J., Huffman, J.E., Jackson, A.U., Jacobs, K.B., Johansson, A., Kaakinen, M., Kleber, M.E., Lahti, J., Leach, I.M., Lehne, B., Lo, K.S., Lorentzon, M., Luan, J., Madden, P.A.F., Mangino, M., McKnight, B., Medina-Gomez, C., Monda, K.L., Montasser, M.E., Mueller, G., Mueller-Nurasyid, M., Nolte, I.M., Panoutsopoulou, K., Pascoe, L., Paternoster, L., Rayner, N.W., Renstrom, F., Rizzi, F., Rose, L.M., Ryan, K.A., Salo, P., Sanna, S., Scharnagl, H., Shi, J., Smith, A.V., Southam, L., Stancakova, A., Steinthorsdottir, V., Strawbridge, R.J., Sung, Y.J., Tachmazidou, I., Tanaka, T., Thorleifsson, G., Trompet, S., Pervjakova, N., Tyrer, J.P., Vandenput, L., Laan, S.W. van der, Velde, N. van der, Setten, J. van, Vliet-Ostaptchouk, J.V. van, Verweij, N., Vlachopoulou, E., Waite, L.L., Wang, S.R., Wang, Z., Wild, S.H., Willenborg, C., Wilson, J.F., Wong, A., Yang, J., Yengo, L., Yerges-Armstrong, L.M., Yu, L., Zhang, W., Zhao, J.H., Andersson, E.A., Bakker, S.J.L., Baldassarre, D., Banasik, K., Barcella, M., Barlassina, C., Bellis, C., Benaglio, P., Blangero, J., Blueher, M., Bonnet, F., Bonnycastle, L.L., Boyd, H.A., Bruinenberg, M., Buchman, A.S., Campbell, H., Chen, Y.I., Chines, P.S., Claudi-Boehm, S., Cole, J., Collins, F.S., Geus, E.J.C. de, Groot, L.C.P.G.M. de, Dimitriou, M., Duan, J., Enroth, S., Eury, E., Farmaki, A., Forouhi, N.G., Friedrich, N., Gejman, P. V., Gigante, B., Glorioso, N., Go, A.S., Gottesman, O., Graessler, J., Grallert, H., Grarup, N., Gu, Y., Broer, L., Ham, A.C. van der, Hansen, T., Harris, T.B., Hartman, C.A., Hassinen, M., Hastie, N., Hattersley, A.T., Heath, A.C., Henders, A.K., Hernandez, D., Hillege, H., Holmen, O., Hovingh, K.G., Hui, J., Husemoen, L.L., Hutri-Kahonen, N., Hysi, P.G., Illig, T., Jager, P.L. de, Jalilzadeh, S., Jorgensen, T., Jukema, J.W., Juonala, M., Kanoni, S., Karaleftheri, M., Khaw, K.T., Kinnunen, L.,
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Kittner, S.J., Koenig, W., Kolcic, I., Kovacs, P., Krarup, N.T., Kratzer, W., Krueger, J., Kuh, D, Kumari, M., Kyriakou, T., Langenberg, C., Lannfelt, L., Lanzani, C., Lotay, V., Launer, L.J., Leander, K., Lindstrom, J., Linneberg, A., Liu, Y., Lobbens, S., Luben, R., Lyssenko, V., Mannisto, S., Magnusson, P.K., McArdle, W.L., Menni, C., Merger, S., Milani, L., Montgomery, G.W., Morris, A.P., Narisu, N., Nelis, M., Ong, K.K., Palotie, A., Perusse, L., Pichler, I., Pilia, M.G., Pouta, A., Rheinberger, M., RibelMadsen, R., Richards, M., Rice, K.M., Rice, T.K., Rivolta, C., Salomaa, V., Sanders, A.R., Sarzynski, M.A., Scholtens, S., Scott, R.A., Scott, W.R., Sebert, S., Sengupta, S., Sennblad, B., Seufferlein, T., Silveira, A., Slagboom, P.E., Smit, J.H., Sparso, T.H., Stirrups, K., Stolk, R.P, Stringham, H.M., Swertz, M.A., Swift, A.J., Syvanen, A., Tan, S., Thorand, B., Toenjes, A., Tremblay, A., Tsafantakis, E., Most, P.J. van der, Voelker, U., Vohl, M., Vonk, J.M., Waldenberger, M., Walker, R.W., Wennauer, R., Widen, E., Willemsen, G., Wilsgaard, T., Wright, A.F., Zillikens, M.C., Dijk, S.C. van, Schoor, N.M. van, Asselbergs, F.W., Bakker, P.I.W., Beckmann, J.S., Beilby, J., Bennett, D.A., Bergman, R.N., Bergmann, S., Boeger, C.A., Boehm, B.O., Boerwinkle, E., Boomsma, D.I., Bornstein, S.R., Bottinger, E.P., Bouchard, C., Chambers, J.C., Chanock, S.J., Chasman, D.I., Cucca, F., Cusi, D., Dedoussis, G., Erdmann, J., Eriksson, J.G., Evans, D.A., Faire, U. de, Farrall, M., Ferrucci, L., Ford, I., Franke, L., Franks, P.W., Froguel, P., Gansevoort, R.T., Gieger, C., Gronberg, H., Gudnason, V., Gyllensten, U., Hall, P., Hamsten, A., Harst, P. van der, Hayward, C., Heliovaara, M., Hengstenberg, C., Hicks, A.A., Hingorani, A., Hofman, A., Hu, F., Huikuri, H.V., Hveem, K., James, A.L., Jordan, J.M., Jula, A., Kaehoenen, M., Kajantie, E., Kathiresan, S., Kiemeney, L.A.L.M., Kivimaki, M., Knekt, P.B., Koistinen, H.A., Kooner, J.S., Koskinen, S., Kuusisto, J., Maerz, W., Martin, N.G., Laakso, M., Lakka, T.A., Lehtimaki, T., Lettre, G., Levinson, D. F., Lind, L., Lokki, M., Mantyselka, P., Melbye, M., Metspalu, A., Mitchell, B.D., Moll, F.L., Murray, J.C., Musk, A.W., Nieminen, M.S., Njolstad, I., Ohlsson, C., Oldehinkel, A.J., Oostra, B.A., Palmer, L.J., Pankow, J.S., Pasterkamp, G., Pedersen, N.L., Pedersen, O., Penninx, B.W.J.H., Perola, M., Peters, A., Polasek, O., Pramstaller, P.P., Psaty, B.M., Qi, L., Quertermous, T., Raitakari, O.T., Rankinen, T., Rauramaa, R., Ridker, P.M., Rioux, J.D., Rivadeneira, F., Rotter, J.I., Rudan, I., Ruijter, H.M. den, Saltevo, J., Sattar, N., Schunkert, H., Schwarz, P.E.H., Shuldiner, A.R., Sinisalo, J., Snieder, H., Sorensen, T.I.A., Spector, T.D., Staessen, J.A., Stefania, B., Thorsteinsdottir, U., Stumvoll, M., Tardif, J., Tremoli, E., Tuomilehto, J., Uitterlinden, A. G., Uusitupa, M., Verbeek, A.L.M., Vermeulen, S.H., Viikari, J.S., Vitart, V., Voelzke, H., Vollenweider, P., Waeber, G., Walker, M., Wallaschofski, H., Wareham, N.J., Watkins, H., Zeggini, E., Chakravarti, A., Clegg, D.J., Cupples, L.A., Gordon-Larsen, P., Jaquish, C.E., Rao, D.C., Abecasis, G.R., Assimes, T.L., Barroso, I., Berndt, S.I., Boehnke, M., Deloukas, P., Fox, C.S., Groop, L.C., Hunter, D.J., Ingelsson, E., Kaplan, R.C., McCarthy, M.I., Mohlke, K.L., O'Connell, J.R., Schlessinger, D., Strachan, D.P., Stefansson, K., Duijn, C.M. van, Hirschhorn, J.N., Lindgren, C.M., Heid, I.M., North, K.E., Borecki, I.B., Kutalik, Z. & Loos, R.J.F. (2015). The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLoS Genetics, 11 (10):e1005378. doi: 10.1371/journal.pgen.1005378 Wit, S.J. de, Werf, Y.D. van der, Mataix-Cols, D., Trujillo, J.P., Oppen, P.C. van, Veltman, D.J. & Heuvel, O.A. van den (2015). Emotion regulation before and after transcranial magnetic stimulation in obsessive compulsive disorder. Psychological Medicine, 45 (14), 3059-3073. doi: 10.1017/S0033291715001026 Xu, T., Brandmaier, S., Messias, A.C., Herder, C., Draisma, H.H.M., Demirkan, A., Yu, Z., Ried, J.S., Haller, T., Heier, M., Campillos, M., Fobo, G., Stark, R., Holzapfel, C., Adam, J., Chi, S., Rotter, M., Panni, T., Quante, A.S., He, Y., Prehn, C., Roemisch-Margl, W., KastenmĂźller, G., Willemsen, G., Pool, R., Kasa, K., Willems van Dijk, K., Hankemeier, T., Meisinger, C., Thorand, B., Ruepp, A., HrabĂŠ de Angelis, M., Li, Y., Wichmann, H.-E., Stratmann, B., Strauch, K., Metspalu, A., Gieger, C., Suhre, K., Adamski, J., Illig, T., Rathmann, W., Roden, M., Peters, A., Duijn, C.M. van, Boomsma, D.I., Meitinger, T. & Wang-Sattler, R. (2015). Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care, 38 (10), 1858-1867. doi: 10.2337/dc15-0658 Yu, D.M., Mathews, C.A., Scharf, J.M., Neale, B.M., Davis, L.K., Gamazon, E.R., Derks, E.M., Evans, P., Edlund, C.K., Crane, J., Osiecki, L., Gallagher, P., Gerber, G., Haddad, S., Illmann, C., McGrath, L.M., Mayerfeld, C., Arepalli, S., Barlassina, C., Barr, C.L., Bellodi, L., Benarroch, F., Berrio, G.B., Bienvenu, O.J., Black, D.W., Bloch, M.H., Brentani, H., Bruun, R.D., Budman, C.L., Camarena, B., Campbell, D.D., Cappi, C., Silgado, J.C.C., Cavallini, M.C., Chavira, D.A., Chouinard, S., Cook, E.H., Cookson,
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M.R., Coric, V., Cullen, B., Cusi, D., Delorme, R., Denys, D., Dion, Y., Eapen, V., Egberts, K., Falkai, P., Fernandez, T., Fournier, E., Garrido, H., Geller, D., Gilbert, D.L., Girard, S.L., Grabe, H.J., Grados, M.A., Greenberg, B.D., Gross-Tsur, V., Grunblatt, E., Hardy, J., Heiman, G.A., Hemmings, S.M.J., Herrera, L.D., Hezel, D.M., Hoekstra, P.J., Jankovic, J., Kennedy, J.L., King, R.A., Konkashbaev, A.I., Kremeyer, B., Kurlan, R., Lanzagorta, N., Leboyer, M., Leckman, J.F., Lennertz, L., Liu, C.Y., Lochner, C., Lowe, T.L., Lupoli, S., Macciardi, F., Maier, W., Manunta, P., Marconi, M., McCracken, J.T., Restrepo, S.C.M., Moessner, R., Moorjani, P., Morgan, J., Muller, H., Murphy, D.L., Naarden, A.L., Nurmi, E., Ochoa, W.C., Ophoff, R. A., Pakstis, A.J., Pato, M.T., Pato, C.N., Piacentini, J., Pittenger, C., Pollak, Y., Smit, J.H., Posthuma, D., Cox, N.J. & Pauls, D.L. (2015). Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD. American Journal of Psychiatry, 172 (1), 82-93. doi: 10.1176/appi.ajp.2014.13101306 Zeeuw, L.E.J. de, Beijsterveldt, C.E.M. van, Lubke, G.H., Glasner, T.J. & Boomsma, D.I. (2015). Childhood ODD and ADHD Behavior: The Effect of Classroom Sharing, Gender, Teacher Gender and Their Interactions. Behavior Genetics, 45 (4), 394-408. doi: 10.1007/s10519-015-9712-z Zeeuw, L.E.J. de, Geus, E.J.C. de & Boomsma, D.I. (2015). Meta-analysis of twin studies highlights the importance of genetic variation in primary school educational achievement. Trends in Neuroscience and Education, 4 (3), 69-79. doi: 10.1016/j.Line.2015.06.001 Zwaveling-Soonawala, N., Beijsterveldt, C.E.M. van, Mesfum, E.T., Wiedijk, B., Oomen, P., Finken, M.J.J., Boomsma, D.I. & Trotsenburg, A.S.P. van (2015). Fetal Environment Is a Major Determinant of the Neonatal Blood Thyroxine Level: Results of a Large Dutch Twin Study. Journal of Clinical Endocrinology and Metabolism, 100 (6), 2388-2395. doi: 10.1210/jc.2015-1429
Scientific publications (books, monographs, book chapters, proceedings) Ariel, A., Glasner, T., Verkerk, B., Beijsterveldt, T. van, Grootheest, G. van, Laan, J. van der, Groot, M. de, Visser, S., Bakker, B.F.M. & Boomsma, D.I. (2015). Linkage of health insurance data to the Netherlands Twin Register. In G. Van Grootheest, M. De Groot, J. Van der Laan, J. Smit & B. Bakker (Eds.), Record linkage for health data: three demonstration projects (pp. 15-34). The Hague / Heerlen: Statistics Netherlands. Bartels, M. & Baselmans, B.M.L. (2015). The Molecular Genetics of Subjective Well-Being. In Genetics of Psychological Well-Being. The role of heritability and genetics in positive psychology (pp. 10). Oxford: Oxford University Press. Veltman, D.J. & Heuvel, O.A. van den (2015). MRI bij de obsessieve-compulsieve stoornis. In A. Aleman & P.H. Hulshoff (Eds.), Beeldvorming van het brein (pp. 319-330). Utrecht: de Tijdstroom.
Professional publications Balkom, A.J.L.M. van, Gabrielse, L. & Heuvel, O.A. van den (2015). Angst, obsessievecompulsieve stoornis en trauma. Tijdschrift voor bedrijfs- en verzekeringsgeneeskunde, 23 (10), 459-462. doi: 10.1007/s12498-015-0186-y Gool, W.A. van, Wevers, R.A., Boomsma, D.I., Cornel, M.C., Geraedts, J.P.M., Hennekam, R.C., Janssens, A.C.J.W., Knoers, N.V.A.M., Ommen, G.J.B van, Visser, M. de, Vliet-Lachotzki, E. van, Wert, G.M.W.R. De & Engels, P.G. (2015). Gezondheidsraad. Next generation sequencing in diagnostiek. (Adviesrapport). Den Haag: Gezondheidsraad. Hulshoff Pol, H.E., Ophoff, R., Bartels, M. & Boomsma, D.I. (2015). Invloed van genen en omgeving op de hersenen. In A. Aleman & H.E. Hulshoff Pol (Eds.), Beeldvorming van het brein (pp. 33-47). Utrecht: Uitgeverij De Tijdstroom. Jansen, J.M., Werf, Y.D. van der, Heuvel, O.A. van den, Wit, S.J. de, Brink, W. van den & Goudriaan, A.E. (2015). Niet-invasieve hersenstimulatie bij verslaving; het effect op craving en emotieregulatie. Neuropraxis, 19 (3), 54-58. doi: 10.1007/s12474-015-0080-5 Middeldorp, C.M. (2015). Genetica en psychische stoornissen op de kinderleeftijd: erfelijkheid en de zoektocht naar genen. Tijdschrift voor psychiatrie, 57 (12), 876-880.
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Rikkert, M.G.M. Olde, Exel, E. van, Knol, W., Lemstra, A.W., Roks, G. & Verhey, F.R.J. (2015). Richtlijn diagnostiek en behandeling van dementie. Nederlands Tijdschrift voor Geneeskunde, 159:A8671. Veltman, E.M., Rhebergen, D., Exel, E. van & Stek, M.L. (2015). Hashimoto-encefailitis en depressie. Tijdschrift voor psychiatrie, 57 (4), 280-283.
Publications for the general public Bartels, M. (2015, April 30). Geluk zit in je genen. Ad Valvas, pp. 16-18. Bartels, M. (2015, November 28). Gelukkig worden? Tel je zegeningen. Parool Bartels, M. (2015, April 07). Geluksgevoel 35 procent genetisch. Parool Bartels, M. (2015, Oktober 10). Het idee: ‘Depressie is iets anders dan gebrek aan geluk’. Vrij Nederland Bartels, M. (2015, April 25). Treetje terug op de geluksladder. Telegraaf Bartels, M. (2015, Maart 28). Zij hebben het ook niet makkelijk?!? Volkskrant Kan, K.J. (2015, Oktober 03). Wat ons IQ werkelijk over ons zegt. De Volkskrant
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Appendix 4: Marks of recognition from peers and societal groups Abbreviatons: BIT: Brain Imaging Technology; BMHD: Brain Mechanisms in Health & Disease; ND: Neurodegeneration; NI: Neuroinflammation; NMH: Neurobiology of Mental Health
Invited lectures at scientific meetings Investigator Abbink, T.E.M. Abbink, T.E.M. Abbink, T.E.M. Abdellaoui, A. Barkhof, F. Barkhof, F.
Congress, title lecture Gordon Conference Translation Machinery in Health and Disease, Towards understanding the molecular mechanism underlying vanishing white matter disease, Ventura, CA, USA 15 years Center for Childhood White Matter Disorders, Vanishing White Matter - molecular mechanisms, Amsterdam, The Netherlands TN2 conference, Towards understanding the disease mechanism underlying vanishing white matter , Amsterdam, The Netherlands Plenaire Sociale Wetenschappelijke Raad Conferentie , De Nederlander bestaat niet, Leusden, The Netherlands MR 2015 Garmisch. 16th International MRI Symposium, Modern MR Imaging in white matter diseases, Garmisch-Partenkirchen, Germany European Congress of Radiology, 1. Drug-related conditions. 2. Is there a need for quantitative reporting of white matter lesions? , Wenen, Austria
Date
Program
25-02-2015
BMHD
22-10-2015
BMHD
12-3-2015
BMHD
31-1-2015
NMH
29-31 januari 2015 4 to 8-3-2015
Barkhof, F.
The 1st Congress of the European Academy of Neurology , Imaging in MS – Typical features, Berlijn, Germany
21 to 23-6-2015
Barkhof, F.
ESNR, 1. MR contribution to diagnosis and differential diagnosis in dementia. 2. Clinical relevance of brain atrophy in MS, Napels, Italy
16 to 20-9-2015
Barkhof, F.
Bartels, M. Bartels, M. Bartels, M. Bartels, M. Beek, J.H.G.M. van Berckel, B.N.M. van Berckel, B.N.M. van Berg, W.D.J. van de Berg, W.D.J. van de Berg, W.D.J. van de Berg, W.D.J. van de
ECTRIMS, 1. Switching from branded to generic glatiramer acetate: two-year MRI data from the GATE trial demonstrates continuous efficacy. 2. MRI results in patients with CIS treated with interferon beta-1b: 11-year follow up in BENEFIT (BENEFIT 11). 3. Alemtuzumab slows brain volume loss over 5 years in patients with active relapsing-remitting multiple sclerosis with most patients not receiving treatment for 4 years: CARE MS I and II extension study. 4. Monitoring atrophy in individual patients. , Barcelona, Spain Fifth annual workshop on the CATSS study, ACTION, an FP‐7 project aimed at improving the understanding of the causes of individual differences in aggression among children, Stockholm, Sweden Queen Mary University of London seminar series, Individual differences in Wellbeing; From twin-family studies to molecular genetic findings, London, UK Interdisciplinary Perspectives on Genetic and Social Causes of Life Chances, A step by step approach to unravel individual differences in complex phenotypes; the journey of SWB, Bielefeld, Germany NET-QUBIC (NETherlands QUality of life and Biomedical cohort studies In Cancer) Symposium, Genetics and Wellbeing, Utrecht, The Netherlands Sports Science Summit, Computational modelling of energy metabolism & session chair, London, England Biomarkers for Brain Disorders: Challenges and Opportunities, Tau imaging, Hinxton, Cambridge , UK European Association of Nuclear Medicine, Value and Pitfalls of Neuroimaging in a Memory Clinic, Hamburg, Germany 12th International Conference on Alzheimer's and Parkinson's diseases, Dissecting the role of pathological proteins in Parkinson’s disease progression, Nice, France Third Assisi Workshop on Biomarkers in the early diagnosis of neurodegenerative disorders, Alpha-synuclein aggregation and degradation in Parkinson's disease, Assisi, Italy XXI World Congress on Parkinson’s Disease and Related Disorders, Clinical and pathological heterogeneity in idiopathic and genetic forms of Parkinson’s disease, Milan, Italy XXI World Congress on Parkinson’s Disease and Related Disorders, Neuropathology of parkinsonism: differential diagnosis, Milan, Italy
79
BIT ND NI BIT ND NI BIT ND NI BIT ND NI
7 to 10-10-2015
BIT ND NI
29-1-2015
NMH
8-10-2015
NMH
19-10-2015
NMH
2-12-2015
NMH
13-1-2015 1 to 3-2-2015 11-10-2015
ND BIT ND BIT ND
11-3-2015
ND
225-2015
ND
7-12-2015
ND
9-12-2015
ND
Annual Repprt 2015 - Appendices
Investigator Berg, W.D.J. van de Boellaard, R. Boellaard, R. Boellaard, R. Boellaard, R. Boellaard, R. Boellaard, R. Boellaard, R. Boer, J.F. de Boer, J.F. de Boer, J.F. de Boer, J.F. de Boer, J.F. de Boomsma, D.I. Boomsma, D.I. Boomsma, D.I. Boomsma, D.I. Boomsma, D.I. Boomsma, D.I. Bot, M. Bot, M. Bugiani, M. Bugiani, M. Bugiani, M. Bugiani, M. Bugiani, M. Cornelisse, L.N. Cornelisse, L.N. Dam, A.M.W. van Dam, A.M.W. van Dijkstra, C.D. Douw, L.
Congress, title lecture Meet & Greet International Alzheimer Association, Variatie in bouwstenen bij Alzheimer en Parkinson cellen, Corpus, Leiden, The Netherlands BrainPET, Fundamentals of the PET signal: Scanners, signal detection & reconstruction , Vancouver, Canada PET/MR workshop, PET modeling, Tuebingen, Germany Summerschool, Perspectives on PET quantification and tumor delineation, Freiburg, Germany APRAMEN Seminar, PET/CT Optimization & EARL, Paris, France Annual meeting society of nuclear medicine, PET/MRI has Arrived… But Where Do We Go From Here?, Baltimore, USA Eur. Assoc. Of Nuclear Medicine, 30 Introduction of the EARL/EATRIS 89Zr-PET/CT accreditation program, Hamburg, Germany Eur.conference of radiology, Experience of the Quantitative Imaging Alliance (QIBA) of the RSNA , Vienna, Austria 7th annual meeting of IBILI “New trends in biomedical research”, Beyond structural OCT imaging, Coimbra, Portugal Incorporation of OCT Angiography into clinical practice, drug development and clinical trials: opportunities and pitfalls. , What’s next in OCT angiography, Rome, Italy International Congress on Biophotonics (ICOB) 2015, Beyond structural OCT imaging, Florence, Italy 10th Pro Retina meeting Potsdam, Beyond structural OCT imaging in the human retina, Potsdam, Germany Macula of Paris 2015, New technologies for imaging the choroid, Paris, France Genomics Seminar at Imperial College London, Heritabity of epigenic marks, London, UK Behavior Genetics Association 45th Annual Meeting, Prediction from polygenic scores based on Neuroticism GWA to psychiatric and lifestyle traits, San Diego, USA PGC symposium at AMC, Molecule to Behavior and Society (and back), Amsterdam, The Netherlands AMC Ruysch Lezing (invited talk), Twins and “Omics”, Amsterdam, The Netherlands 11th Int Workshop on Neonatology, Aggression in children: The ACTION project, Cagliari, Italy Symposium Genetic Screening: Who, Why and When? @ KNAW, What’s in the Dutch genome?, Amsterdam, The Netherlands Annual NESDA day, Rainbow project 12: BIONIC (BIObanks Netherlands Internet Collaboration), Amsterdam , The Netherlands lunch colloquium , Rainbow project 12: BIONIC (BIObanks Netherlands Internet Collaboration), Amsterdam, The Netherlands EuroCNS course Leukoencephalopathies, Clinical approach to childhood leukodystrophies, Amsterdam, The Netherlands EuroCNS course Leukoencephalopathies, Peroxisomal disorders, Amsterdam, The Netherlands EuroCNS course Leukoencephalopathies, Lysosomal disorders, Amsterdam, The Netherlands EuroCNS course Developmental neuropathology, Demyelinative disorders in childhood, Amsterdam, The Netherlands 15 years Center for childhood white matter disorders, Astrocytes in white matter disorders: the good and the bad, Amsterdam, The Netherlands 17th international Neuroscience Winter conference, Energy barrier for vesicle fusion, Solden, Austria Cajal Course Advanced Techniques for Synapse Biology , Energy barrier for vesicle fusion, Bordeaux, France Dutch Neuroscience meeting, Neuroinflammation and microglial activation in Parkinson's disease; the substantia nigra and beyoun, Lunteren, The Netherlands European Glial Meeting, Early microglial activation beyond the substantia nigra in Parkinson’s disease , Bilbao, Spain ECTRIMS focused workshop Immunology of multiple sclerosis - from a human point of view, Monocytes and microgla, Larnaca, Cyprus Nederlandse Vereniging voor Neuropsychologie, De dynamiek van ons denken: flexibele hersennetwerken en cognitie, Amsterdam, The Netherlands
80
Date
Program
11-6-2015
ND
27-6-2015
BIT
9-2-2015
BIT
10-7-2015
BIT
8-12-2015
BIT
6-6-2015
BIT
10-10-2015
BIT
4-3-2015
BIT
4-12-2015
BIT
6-6-2015
BIT
18-5-2015
BIT
28-3-2015
BIT
9-1-2015
BIT
29-1-2015
NMH
17-6-2015
NMH
29-7-2015
NMH
22-9-2015
NMH
30-10-2015
NMH
3-11-2015
NMH
15-6-2015
NMH
16-6-2015
NMH
25-3-2015
BMHD
25-3-2015
BMHD
26-3-2015
BMHD
21-10-2015
BMHD
22-10-2015
BMHD
7-4-2015
BMHD
16-10-2015
BMHD
11-6-2015
ND NI
16-7-2015
ND NI
5 to 6-3-2015
NI
6-11-2015
BIT
Annual Report 2015 - Appendices
Investigator Douw, L. Drent, M.L. Drukarch, B. Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Geurts, J.J.G. Geurts, J.J.G. Geus, E.J.C. de Geus, E.J.C. de Geus, E.J.C. de Geus, E.J.C. de Geus, E.J.C. de Gunst, M.C.M. de Gunst, M.C.M. de Heine, V.M. Heine, V.M. Heine, V.M. Heine, V.M. Heine, V.M. Heine, V.M. Heuvel, O.A. van den Heuvel, O.A. van den
Congress, title lecture ARSEP Foundation MRI Workshop, The minimum spanning tree to characterize brain networks, Paris, France 13e Symposium Neuroendocrinologie, Debat: Groeihormoonsuppletie boven de 50? Pro: M.L. Drent, Utrecht, The Netherlands Research in individuals with intellectual disability, What limits should be set to the use of medical technology in clinical research with intellectually disabled people?, Nijmegen, The Netherlands Psychologie Nu, Onderzoek om niet te vergeten: de ziekte van Alzheimer. January 2015., Utrecht, The Netherlands 4th Singapore International Neurocognitive Symposium, Diagnosis of AD in the 21st century: noevl diagnostic criteria and a shifting paradigm. , Singapore, Singapore 4th Singapore International Neurocognitive Symposium, Subjective Cognitive Impairment in preclinical AD: cognitive and neuroimaging aspects (Plenary), Singapore, Singapore 4th Singapore International Neurocognitive Symposium, Phenotypical heterogeneity in Alzheimer’s disease: effects of age-atonset. , Singapore, Singapore Kuopio Alzheimer meeting, Clinical significance of microbleeds in AD., Kuopio, Finland AAIC 2015, Early onset APOE e4-negative AD patients show faster cognitive decline on non-memory domains. , Washington, United States Symposium at the occasion of PhD defense Susan van Veluw, Clinical significance of microbleeds in AD, Utrecht, The Netherlands TN2 Conference 2015, ABIDE: Alzheimer biomarkers in daily practice, Amsterdam, The Netherlands Magnetic Techniques in Multiple Sclerosis - 18° Advanced course, GM lesions and damage: do they explain the whole story?, Milan, Italy Genzyme Neuropreservation advisory board, Functional connectivity and reorganization , Paris, France NTR - AVERA - Affymetrix meeting @ VU, Mendelian Randomization and causality testing in twins, Amsterdam, The Netherlands Invited Lecture Rollins School for Public Health, Emory University, Modeling causality in longitudinal twin data: regular exercise and depression, Atlanta, USA William James Graduate School Lecture, Ambulatory recording of autonomic nervous system activity in the behavioral sciences: the VU contribution, Amsterdam, The Netherlands Celebratory symposium on Genomics, Genetics, and Exercise Biology, Twin studies of exercise behavior and exercise ability, Santorini, Greece Keynote @ Behavior Genetics Association 45th Annual Meeting, Genetic investigation of exercise behavior and its effects on mental and physical health, San Diego, USA Workshop Dynamical processes on networks - theory and applications in social sciences and biology", Dynamic processes on networks: cellular and genetic networks, an overview Colloquium "Four Facets of Modern Statistics", Statistics for networks with a view towards neuroscience, ETH, Zurich, Switzerland KNG symposium, Brain White Matter Disorders and Stem Cell Therapy, Amsterdam, The Netherlands 3rd ELA scientific congres, Transplantation of glial precursor cells in Vanishing White Matter, Paris, France Bernstein Conference, Neural Stem Cells, Heidelberg, Germany SSIEM, Stem cell therapy , Lyon, France Scientific Symposium 15yr CCWMD, The prospects of glia stem cell therapy in leukodystrophies, Amsterdam, The Netherlands NevroNor national meeting, Neural stem cells: Application of iPSC technology to study neurological disorders, Oslo, Norway Child psychiatry seminars, Erasmus, Emotion & Cognition in OCD, Rotterdam, The Netherlands Bunnik symposium, OCD as a model disease to study neuroplasticity, Utrecht, The Netherlands
81
Date
Program
6-2-2015
BIT
10-11-2015
NMH
13 to 14-4-2015
ND NI
1-1-2015
ND
1-3-2015
ND
1-3-2015
ND
1-3-2015
ND
1-6-2015
ND
1-7-2015
ND
30-9-2015
ND
4-12-2015
ND
19-3-2015
NI
20-5-2015
NI
19-1-2015
NMH
15-3-2015
NMH
16-4-2015
NMH
15-5-2015
NMH
17-6-2015
NMH
14-18 June 2015 3-12-2015
BIT BMHD NMH BIT BMHD NMH
19-2-2015
BMHD
25-6-2015
BMHD
14-9-2015
BMHD
1-9-2015
BMHD
23-10-2015
BMHD
17-11-2015
BMHD
2-3-2015
NMH
6-3-2015
NMH
Annual Repprt 2015 - Appendices
Investigator Heuvel, O.A. van den Heuvel, O.A. van den Heuvel, O.A. van den Heuvel, O.A. van den Heuvel, O.A. van den Heuvel, O.A. van den Holstege, H.
Congress, title lecture Obsessive compulsive disorder (OCD) symposium at the American Psychiatric Associantion (APA), The structure and function of the OCD brain , Toronto, Canada ENIGMA meeting, The ENIGMA-OCD consortium, Honolulu, Hawaii, USA ICOCS meeting during ECNP Conference, ENIGMA-OCD subcortical mega-analysis, Amsterdam, The Netherlands Sexuology symposium, Hypersexuality and other ICD's in Parkinson's Disease, Rotterdam, The Netherlands Wereld Parkinsondag, BEWARE: treatment of wearing-off related anxiety, Nieuwegein, Netherlands Wetenschapslunch Psychiatry, The structure of the OCD brain: meta- and mega-analyses, Amsterdam, Netherlands Biomarkers for Brain Disorders: Challenges and Opportunities, 100plus Study: What can cognitively healthy centenarians teach us about retaining cognitive health, Hinxton, UK
Date
Program
16-5-2015
NMH
11-6-2015
NMH
2-9-2015
NMH
27-11-2015
NMH
11-04-2015
NMH
21-04-2015
NMH
2-2-2015
BMHD ND
Holstege, H.
DZNE, Tubingen invited lecture, 100-plus Study, Tubingen, Germany
4-2-2015
Holstege, H.
AAIC 2015, Washington DC, 100-plus Study, Washington DC, USA
22-07-2015
UZ Leuven, Group Joris Vermeesch, 100-plus Study, Leuven, Belgium
22-10-2015
Holstege, H. Hoozemans, J.J.M. Hoozemans, J.J.M. Horssen, J. van Horssen, J. van Horssen, J. van Hulst, H.E. Hulst, H.E. Hulst, H.E. Knaap, M.S. van der Knaap, M.S. van der Knaap, M.S. van der Knaap, M.S. van der Knaap, M.S. van der Knaap, M.S. van der Knaap, M.S. van der Kock, C.P.J. de Koellinger, P.D. Koellinger, P.D. Koellinger, P.D. Koellinger, P.D. Lammertsma, A.A.
Special CBMSO Seminar, Activation of the unfolded protein response in Alzheimer's disease and related disorders, Madrid, Spain Zoobiquity congres, De ziekte van Alzheimer, Hilvarenbeek, The Netherlands Nordic MS symposium, Mitochondrial and oxidative damage in MS , Copenhagen, Danmark The role of ENV-HERW in neurological disorders, ENV-HERW and GAG expression in MS lesions, Lyon, France Italian Neuropathology Congress, Mitochondrial injury drives MS disease progression, Verona, Italy Genzyme MRI course advisory board, Imaging of MS, Amsterdam, The Netherlands Baird Lecture, Cognitive decline in MS, West-Orange, USA Verpleegkundigen meeting Twente, Cognitie in MS, Hengelo, The Netherlands 11th Meeting of the European Society of Magnetic Resonance in Neuropediatrics (ESMRN), Conceptualizing MRI phenotypic variation in metabolic white matter disorders, Porto, Portugal 3rd ELA Scientific Congress: Advances in molecular pathogenesis, diagnosis and management of the leukodystrophies, From new leukodystrophies and new genes to molecular insight, Paris, France Annual Scientific Meeting of the United Leukodystrophy Foundation, VWM mouse models and disease mechanisms, Omaha, USA Honorary Mario Savoiardo lecture, Leukodystrophies: from MRI to disease insight, Milan, Italy 15 years Center of Childhood White Matter Disorders, MRI pattern recognition: MRI diagnosis and definition of novel disorders, Amsterdam, The Netherlands 15 years Center of Childhood White Matter Disorders, White matter edema: diseases and mechanisms, Amsterdam, The Netherlands 15 years Center of Childhood White Matter Disorders, What has been achieved in 15 years?, Amsterdam, The Netherlands Tactile information processing, Cortical representation of naive, active touch, Bochum, Germany KNAW Plenaire SWR-conferentie, Genetics, economics, and education, Leusden, The Netherlands ZiF meeting "Interdisciplinary perspectives on genetic and social causes of life chances", GWAS on social scientific outcomes, Bielefeld, Germany ZiF meeting "From genome to social outcomes", Polygenic scores, Bielefeld, Germany Broucher foundation workshop "Genomics research in human cognition and psychiatric diseases", GWAS on social scientific outcomes, Hermance, Switzerland European Molecular Imaging Meeting, Molecular Imaging: the Need for Quantification, T端bingen, Germany
82
BMHD ND BMHD ND BMHD ND
6-10-2015
ND
10-9-2015
ND
February 2015
NI
May 2015
NI
June 2015
NI
9-3-2015
NI
19-12-2015
NI
May 2015
NI
16-5-2015
BMHD
25-6-2015
BMHD
16-7-2015
BMHD
25-9-2015
BMHD
22-10-2015
BMHD
22-10-2015
BMHD
23-10-2015
BMHD
7-9-2015
BMHD
30-1-2015
NMH
20-10-2015
NMH
2-12-2015
NMH
7-12-2015
NMH
18-3-2015
BIT ND
Annual Report 2015 - Appendices
Investigator Lammertsma, A.A. Lammertsma, A.A. Lammertsma, A.A. Lammertsma, A.A. Lammertsma, A.A. Lammertsma, A.A. Lammertsma, A.A. Lammertsma, A.A. Linkenkaer-Hansen, K. Linkenkaer-Hansen, K. Linkenkaer-Hansen, K. Linkenkaer-Hansen, K. Linkenkaer-Hansen, K. Mansvelder, H.D. Mansvelder, H.D. Mansvelder, H.D. Mansvelder, H.D. Meredith, R.M. Meredith, R.M. Meredith, R.M. Milaneschi, Y. Milaneschi, Y. Pattij, T. Penninx, B.W.J.H. Penninx, B.W.J.H. Penninx, B.W.J.H. Penninx, B.W.J.H. Peterman, E.J.G. Peterman, E.J.G.
Congress, title lecture
Date
9th World Congress on Controversies in Neurology, Is amyloid PET imaging really helpful in dementias?, Budapest, Hungary Sonic Radiology Conference, PET - Past, Present and Future, Brisbane, Australia Sonic Radiology Conference, PET in Drug Development and Tretament Evaluation, Brisbane, Australia Sonic Radiology Conference, Quantification in PET Imaging, Brisbane, Australia Sonic Radiology Conference, The Future Role of Digital PET, Brisbane, Australia European Association of Nuclear Medicine, Physiologically-based PK Modelling for PET incl. Tumour, Brain, Cardiac Applications, Hamburg, Germany European Association of Nuclear Medicine, Quantifying TSPO Binding with PET: Making it Simple – What to do and what not to do, Hamburg, Germany 14th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology, PET-imaging in drug development, Rotterdam, The Netherlands Neurocognitive Psychology colloquium, Critical brain dynamics and its perceptual implications, Oldenburg, Germany Symposium: Model-based and Model-inspired Analysis of Electrophysiological Data, Estimating excitation-inhibition balance from M/EEG data using novel biomarkers derived from the critical oscillations model, Nijmegen, The Netherlands Workshop: Complex Collective Dynamics, Brains and beyond, Critical brain dynamics and its perceptual implications, Capri, Italy Symposium: Disentangling the brain web , Critical brain dynamics and its perceptual implications, Chiete, Italy Joint Action and Perception as Emergent Phenomena, The Theory of Critical Brain Dynamics—Relevance for “Joint Action and Perception in Emergent Phenomena”, Cuernavaca, Mexico Dutch Neuroscience Meeting, Cholinergic control of attention by prefrontal cortical nicotinic receptors, Lunteren, The Netherlands FENS regional meeting, Nicotinic receptors in rodent and human cortical circuits, Thessaloniki, Greece Society for Neuroscience satellite meeting, Endogenous activation of nicotinic ACh receptors in circuits of attention, Chicago, USA Cognito meeting, Nicotinic receptors in rodent and human neocortex, Copenhagen, Denmark German Neuroscience Society, Developing entorhinal cortex networks, Goettingen, Germany Gencodys Consortium meeting, Fragile X and GABAergic system, Chania, Crete FENS FRM (European Neuroscience), GABA and developing hippocampus, Thessaloniki, Greece CoLaus/PsyCoLaus: Workshop on genetic analyses involving psychiatric data, Analyses on Neuroticism and MDD in the NESDA study , Lausanne, Switzerland CoLaus/PsyCoLaus: Workshop on genetic analyses involving psychiatric data, Polygenic dissection of major depression clinical heterogeneity, Lausanne, Switzerland International Society for Research on Impulsivity, Impulsivity and the response to drugs of abuse: what we have learned from animal models. , Amsterdam, The Netherlands Erice workshop on stress, behaviour and the heart, Somatic consequences of depression: biological mechanisms , Sicily, Italy ISPNE, The cardiovascular risk in atypical versus melancholic depressed patients, Edinburgh, Schjotland (UK) Radboud University Medical Center, Genetics of depression: where do we stand?, Nijmegen, The Netherlands Sociaal Wetenschappelijke Raad (SWR)-conferentie, Psychiatric genetics, Leusden, The Netherlands Joint Meeting of Dutch & German Biophysicists 2015, A singlemolecule view on kinesin motor-protein cooperation in intraflagellar transport in living C. elegans, Hünfeld, Germany TSRC: Frontiers and Challenges in Laser‐Based Biological Microscopy, Combining optical visualization and manipulation of individual biomolecules., Telluride, CO, USA
83
28-3-2015 30-5-2015 30-5-2015 31-5-2015 31-5-2015
Program BIT ND BIT ND BIT ND BIT ND BIT ND
10-10-2015
BIT ND
10-10-2015
BIT ND
13-10-2015
BIT ND
21-05-2015
BMHD
6-1-2015
BMHD
9-1-2015
BMHD
16-09-2015
BMHD
30-11-2015
BMHD
2-6-2015
NMH
7-10-2015
NMH
14-10-2015
NMH
12-1-2015
NMH
15-3-2015
BMHD
27-4-2015
BMHD
7-10-2015
BMHD
11-9-2015
NMH
11-9-2015
NMH
28-8-2015
NMH
1 to 6-10-2015
NMH
9-9-2015
NMH
27-5-2015
NMH
30-1-2015
NMH
27-2-2015
BIT
4-8-2015
BIT
Annual Repprt 2015 - Appendices
Investigator Peterman, E.J.G. Petzold, A. Pijnenburg, Y.A.L. Pijnenburg, Y.A.L. Pijnenburg, Y.A.L. Posthuma, D. Posthuma, D. Posthuma, D. Posthuma, D. Posthuma, D. Posthuma, D. Posthuma, D. Posthuma, D. Pouwels, P.J.W. Pouwels, P.J.W. Rozemuller, A.J.M. Salomons, G.S. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph.
Congress, title lecture International workshop on Biophotonics & Biomedical Optics, Beijing University of Technology, Using lasers to manipulate and visualize single biomolecules, Beijing, China European Academy of Neurology (EAN), To OCT or not to OCT?, Berlin, Germany Meeting of the italian Neurological Dementia Association, New criteria for frontotemporal dementia (FTD), Bressanone, Italy Magnetic Resonance Techniques in Neurodegenerative Diseases Second Course, The clinical, pathological and imaging continuum of major CNS proteinopathies, Milan, Italy 2nd World Congress on NeuroTherapeutics: Dilemmas, Debates & Discussions (DDDN), Treatment of FTD disorders, Prague, Czech Republic Annual Dutch Human Genetics Society, Complex Trait Genetics, Arnhem, The Netherlands Annual WCPG conference, Cluster computing in genetics, Toronto, Canada Dress Red Day: ‘M/V verschillen in de gezondheidszorg’, Gender differences in genetic architecture, Amsterdam, The Netherlands VU Summer School in Neurodegenerative diseases, Complex Trait Genetics, Amsterdam, The Netherlands AMC-PGC Summer School, Cluster computing in genetics, Amsterdam, The Netherlands Psychiatric Genomics Consortium Summer School,, Cluster computing in genetics, London, UK Endo Neuro Meeting , Schizophrenia genetics, Lunteren, The Netherlands KNAW:Large scaled facilities in the medical sciences, Cluster Computing, data sharing and connecting biobanks on Genetics’, Amsterdam, The Netherlands Scientific symposium 15th anniversary Center for childhood white matter disorders, Quantitative MR parameters: tissue diagnosis and monitoring, Amsterdam, The Netherlands Medica - educational symposium, MRI Neuro: spectroscopy, Düsseldorf, Germany Meeting Neurodegenerative diseases Hanzou, Research Neurodegenerative diseaes in NCA , Hangzhou, China 15 years Center of Childhood White Matter Disorders, tRNA synthetase defects, Amsterdam, The Netherlands NeuroCeq (florbetaben 18F) Launch Event, Integrating biomarkers into today's practice , Utrecht, The Netherlands Psychiatrie op maat voorjaarscongres, Ontwikkeling in dementie: van fenotype naar protein type , Maastricht , The Netherlands Korean Dementia Association, Biomarker in early detection; where do we stand?, Seoul, Korea Symposium Zonnehuisgroep Amstelland , Professionaliteit in de ouderenzorg , Amstelveen, The Netherlands Visiting professorship, Biomarkers for dementia: CSF, MRI, PETs , Bangkok, Thailand Alzheimer The Future of Brain Health, Preventie van de ziekte van Alzheimer: feit en fictie, Amsterdam, The Netherlands Brasilian Dementia Update, Biomarkers ub dementia: CSF, MRI, PETs /Nutritional interventions, Sao Paolo & Rio de Janeiro, Brazil AAIC 2015, Diagnostic Impact of Biomarkers Including CSF and PET in a Tertiary Memory Clinic, Washington, United States AAIC 2015, Biomarker Data from Scarlet Road- a Global Phase 3 Study of Gantenerumab in Patients with Prodromal AD, Washington, United States AAIC 2015, Cross-Cultural Differences in Instrumental Activities of Daily Living (IADL): Translations and Adaptions of the Amsterdam IADL Questionnaire, Washington, United States ISCTM 2015 Autumn Conference, Do findings from observational studies explain failure of disease-modifying trials-Implications for future trials, Amsterdam, The Netherlands Commenius Medische Wetenschappen, Dementie: de grote uitdaging, Leusden, The Netherlands EANM Congress 2015, Neuroimaging- mandatory biomarker in dementia assessment?, Hamburg, Germany IPA Imaging and Biomarkers Workshop, Practical Use of MR Imaging: How to Rate Medial Temporal Atrophy, Berlin, Germany
84
Date
Program
22-10-2015
BIT
19-6-2015
NI
22-1-2015
ND
16-2-2015
ND
4-9-2015
ND
23/10/2015
BMHD
19/10/2015
BMHD
29/09/2015
BMHD
7-8-2015
BMHD
7-2-2015
BMHD
22/06/2015
BMHD
6-11-2015
BMHD
20-4-2015
BMHD
22-10-2015
BMHD NI
17-11-2015
BMHD NI
22-3-2015
ND
21-10-2015
BMHD
20-1 2015
ND
31-3-2015
ND
11-4-2015
ND
16-4-2015
ND
27-5-2015
ND
5-6-2015
ND
12 to 14-6-2015
ND
22-7-2015
ND
22-7-2015
ND
22-7-2015
ND
28-8-2015
ND
1-10-2015
ND
11-10-2015
ND
13-10-2015
ND
Annual Report 2015 - Appendices
Investigator Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheper, W. Scheper, W. Scheper, W. Schmaal, L.
Schmaal, L.
Schmaal, L. Schoonheim, M. Schoonheim, M. Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van
Congress, title lecture CTAD 2015, Speeding up drug development: using sensitive biological measure, Barcelona, Spain TN2 Conference 2015, 50 ways to improve your clinical trial in AD, Amsterdam, The Netherlands 3rd Psychiatry Conference Qatar, Young onset Dementia, Doha, Qatar 1er Cours lémanique, Prevention of dementia, Genève, Switserland UMDF Mitochondrial Medicine 2015, “Metabolic dysfunction and proteostatic stress in neurodegenerative disease, Herndon VA, USA Dutch Neuroscience meeting , The UPR: Early factor in tau pathology, Lunteren, The Netherlands FENS-SfN Summer School 2015, Shared mechanisms and specificity in neurodegenerative diseases, Bertinoro, Italy Society of Biological Psychiatry annual meeting 2015, Subcortical Brain Alterations in Major Depressive Disorder: Findings from the ENIGMA Major Depressive Disorder Working Group, Toronto, Canada Annual ENIGMA PI meeting, The ENIGMA MDD working group: methods and results of an investigation of cortical structural differences between MDD patients and controls, Honolulu, Hawaii, USA Annual VU University medical center Science Day meeting, Data sharing across the world: The ENIGMA Major Depressive Disorder consortium, Amsterdam, The Netherlands Preceptorship on MRI in MS, Understanding MS evolution using structural MR techniques, Milan, Italy Preceptorship on MRI in MS, Understanding MS evolution using structural MR techniques, Milan, Italy Invited lecture, Wintersymposium “Sleep, Cognition and Consciousness”, Salzburg University, Mutual effects of wake and sleep on functional and directed brain connectivity. , Kaprun, Austria Invited Symposium New Insights into the Neural Correlates of Insomnia. World Association of Sleep Medicine (WASM) 6th World Congress on Sleep Medicine, Large-scale psychometrics and brain imaging reveal different subtypes of insomnia. , Seoul, Korea Symposium The role of sleep and insomnia in stress, emotion regulation and psychiatric symptoms. World Association of Sleep Medicine (WASM) 6th World Congress on Sleep Medicine, Why the role of sleep in emotion regulation could be pivotal for understanding disorders including insomnia and PTSD. , Seoul, Korea Symposium The Sleepless Night Blues: Neuroimaging Insights Into the Association Between Sleep and Emotional Function, International Convention of Psychological Science, Large-Scale Psychometric Assessment through Internet and Brain Imaging Reveal Data-Driven Subtypes of Insomnia., Amsterdam, The Netherlands Helmholtz Lecture. Helmholtz Institute, University of Utrecht, Brain imaging and large-scale internet studies identify insomnia subtypes. , Utrecht, The Netherlands Invited lecture Plenary Session: New paradigms in insomnia at the third Sleep and Breathing international conference of the European Respiratory Society (ERS) and European Sleep Research Society (ESRS), Brain Imaging in Insomnia. , Barcelona, Spain NeuroSIPE en NeuroControl Symposium 2015, The role of temperature in sleep and alertness. , Woudschoten, The Netherlands Invited lecture 2nd Annual PERFORM Centre Research Conference on Lifestyle influences on Health, Causes and consequences of fragmented sleep in chronic insomnia and aging., Montreal, Canada Invited lecture LSP - Ernst & Young Biotech Update, Large-scale internet assessment and brain imaging reveal different subtypes of insomnia. , Wassenaar, The Netherlands Invited lecture SUMMA symposium The Importance of Sleep for Mental and Physical Health: A Wake-up Call, UMCU, Large-scale internet assessment and brain imaging reveal different subtypes of insomnia. , Utrecht, The Netherlands Topic introduction and discussion Lorentz Center workshop Human Circadian Rhythms: Developing a Multi-oscillator Framework, How does light history affect your clock? , Leiden, The Netherlands
85
Date
Program
6-11-2015
ND
4-12-2015
ND
5-12-2015
ND
9-12-2015
ND BMHD ND BMHD ND BMHD ND
19-06- 2015 6-12-2015 6-9-2015 15-5-2015
NMH
12-6-2015
NMH
25-9-2015
NMH
13-2-2015
NI
30-10-2015
NI
January 2015
NMH
March 2015
NMH
March 2015
NMH
March 2015
NMH
April 2015
NMH
April 2015
NMH
April 2015
NMH
May 2015
NMH
June 2015
NMH
June 2015
NMH
July 2015
NMH
Annual Repprt 2015 - Appendices
Investigator Someren, E.J.W. van
Someren, E.J.W. van
Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Someren, E.J.W. van Struys, E.A. Teunissen, C.E.
Teunissen, C.E.
Teunissen, C.E. Teunissen, C.E. Teunissen, C.E. Teunissen, C.E. Thomaes, K.
Thomaes, K.
Toonen, R.F.G. Toonen, R.F.G. Veltman, D.J.
Congress, title lecture Invited lecture Alpine Sleep Summer School, Brain mechanisms underlying sleep complaints in health and neuropsychiatry. , Lugano, Switzerland Invited lecture Symposium The inner clock revisited: Circadian rhythm disturbances in insomnia and psychiatric disorders at the 31st Nordic Congress of Psychiatry, Sleep-wake rhythm fragmentation: causes, consequences and opportunities for treatment improvement in depression and insomnia. , Copenhagen, Denmark Invited lecture Third European Insomnia Network Meeting, Using brain imaging for subtyping insomnia. , Freiburg, Germany Invited lecture International Symposium Aging and Sleep: Perks for longevity, Causes and consequences of worse sleep with increasing age. , Liege, Belgium Keynote lecture British Sleep Society Biennial Conference, The neuroscience of individual differences in sleep vulnerability and insomnia. , Newcastle, UK Symposium Disrupted sleep: From Molecules to Cognition. Neuroscience 2015, Society for Neuroscience, Brain imaging and psychometric risk profiles for disrupted sleep. , Chicago, USA Invited lecture ABC Symposium, University of Amstedam, Brain mechanisms underlying sleep complaints in health and neuropsychiatry. , Amsterdam, The Netherlands Invited Lecture GGZ Symposium Gestoorde slaap, onschuldig probleem?, Typen insomnie. , Zeegse, The Netherlands EUREKA! festival, Nationale Wetenschapsagenda, Wat is er aan de hand in het brein van slapelozen?, Amsterdam, The Netherlands KNAW Symposium De Biologische Klok, Slaapproblemen: de biologische klok en er voorbij., Amsterdam, The Netherlands Stichting Onderzoek Licht & Gezondheid Symposium at the Amterdam Light Festival, Het effect van licht op slaap en functioneren overdag, Amsterdam, The Netherlands Institute of Pharmacology & Toxicology, Brain mechanisms underlying sleep complaints in health and neuropsychiatry, Zürich, Switzerland Society for the Study of Inborn Errors of Metabolism (SSIEM) , Inborn Metabolic defects in cancer, Lyon, France Meeting the challenges of Alzheimers disease: from basic science to clinical translation, Alzheimer’s disease, moving from symptomatic to protein diagnosis, Duesseldorf, Germany Meeting the challenges of Alzheimers disease: from basic science to clinical translation”, Identification of novel diagnostic CSF biomarkers for pathological subtypes of FTD with high discriminatory power., Duesseldorf, Germany Meeting of the Swiss Society for Clinical Chemistry. , Biomarkers as the future for AD diagnosis: currents status and perspective, Geneva, Switserland. Press conference. AAIC 2015. , Neurogranin, a CSF biomarker for synaptic loss, predicts decline to dementia due to Alzheimer's disease, Washington DC, USA Biomarkers for Brain Disorders: Challenges and Opportunities. , Harmonisation and standardisation of biobanking and biomarker measurement., Cambridge, UK. Sindem4Juniors. , Identification of novel diagnostic CSF biomarkers for pathological subtypes of FTD with high discriminatory power, Bressanone, Italy Symposium 'Natuurlijk (niet) stabiliseren!?' Psy-zo! = , Emotieregulatie als aanvulling op de PTSS richtlijn voor complexe PTSS, Groningen, The Netherlands Valeriussymposium: ‘Psychotherapie: wat werkt en waarom? Beschouwingen over de psychotherapeutische behandeling van traumagerelateerde en persoonlijkheidsstoornissen, (Hoe) Draagt CGT/EMDR bij aan veranderingen in de hersenen bij PTSS en complexe PTSS, Amsterdam, The Netherlands CAJAL Advanced Techniques for Synapse Biology, Neuronal Cilia in health & disease, Bordeaux, France Dutch Neuroscience Meeting, Advanced techniques to study synaptic transmission, Doorwerth, The Netherlands Spinoza center symposium, Great expectations: (f)MRI in health and disease, Amsterdam, The Netherlands
86
Date
Program
July 2015
NMH
September 2015
NMH
September 2015
NMH
September 2015
NMH
October 2015
NMH
October 2015
NMH
October 2015
NMH
October 2015
NMH
November 2015
NMH
November 2015
NMH
December 2015
NMH
December 2015
NMH
1-9-2015
BMHD
29-10-2015
ND
29-10-2015
ND
23-9-2015
ND
13-7-2015
ND
1-2-2015
ND
22-1-2015
ND
11-2-2015
NMH
22-1-2015
NMH
15-10-2015
BMHD
11-6-2015
BMHD
27-3-2015
NMH
Annual Report 2015 - Appendices
Investigator
Congress, title lecture
Date
Program
29-7-2015
NMH
27-2-2015
BMHD
27-3-2015
BMHD
7 to 11-4-2015
BMHD
4-5-2015
BMHD
20-8-2015
BMHD
24-8-2015
BMHD
7/9-9-2015
BMHD
13-10-2015
BMHD
3-11-2015
BMHD
14-1-2015
ND
26-3-2015
NI ND BIT
7-10-2015
NI ND BIT
1-10-2015
NI ND BIT
20-11-2015
NMH
25-3-2015
NI
15-4-2015
NI
29-6-2015
NI
6-7-2015
NI
27-9-2015
NI
Vries, H.E. de
British Association for Psychopharmacology, Imaging compulsivity: from the group to the individual, Bristol , UK Departmental seminar, Seminar Universidad de La Laguna (ULL), Trafficking and secretion of dense core vesicles in mammalian neurons, La Lagune, Tenerife, Spain Mini-symposium at graduation of Bram Prevo, Trafficking and fusion of dense core vesicles in mammalian neurons, Amsterdam, The Netherlands 17th International Neuroscience Winter Conference, The energy barrier for vesicle fusion, Sölden, Austria Departmental seminar, University of Bonn, Epileptic traits in presynaptic mutants, Bonn, Germany 18th International Symposium on Chromaffin Cell Biology, Trafficking and fusion of Dense Core Vesicles in mammalian CNS neurons, Cairns, Australia ISN-ASPN Meeting, Trafficking and fusion of neuropeptide containing dense core vesicles in mammalian neurons, Cairns, Australia 5th ESM-meeting, The presynaptic parts list: annotation of the terminal, Bristol, UK Cajal School Advanced Techniques in Synapse Biology, Trafficking and fusion of neuropeptide containing dense core vesicles in mammalian neurons, Bordeaux, France Encephalon symposium, Neuropeptide trafficking & secretion within the head (encephalon), Göttingen, Germany Interdisciplinarity in higher education, Problem based and interdisciplinary education, Roskilde University, Denmark Imaging Cognitive Impairment Network (ICINET), Brain atrophy in multiple sclerosis: measurement and interpretation, Stockholm, Sweden European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), Quantitative MR imaging in the management of multiple sclerosis: Focal lesion load quantitative measures, Barcelona, Spain European Society for Magnetic Resonance in Medicine and Biology (ESMRMB), Measuring GM damage in MS: the technicalities, Edinburgh, United Kingdom Parkinsonnet Congres 2015, Depressie en impulscontrolestoornissen bij parkinson, Utrecht, Netherlands MRC workshop, The neurovascular unit in health and disease, London, UK Inernational Microbiology conference, The NVU in disease, Papendal, The Netherlands British society for neuropathology, The blood brain barrier, Cirencester, UK Cerebrovascular Biology meeting, Neurovascular unit in MS, Paris, France Zing conference, The BBB in neuro-inflammation, Oropesa, Spain
Vries, H.E. de
ECRTIMS, Imaging MS, Barcelona, Spain
7-10-2015
NI
Vries, H.E. de
6-11-2015
NI
13-9-2015
NMH
16-10-2015
NI
Wattjes, M.P.
BBB consortium club, The BBB in neurological disease, London, UK Joint meeting of EBBS/EBPS, Role of drug-induced synaptic plasticity and molecular adaptations in mPFC in nicotine and heroin relapse, Verona, Italy DGNR Meeting Germany, MRI in diagnosis and monitoring of multiple sclerosis, Cologne, Germany 38th ESNR Meeting Naples, MRI in pediatric MS, Naples, Italy
18-9-2015
NI
Wattjes, M.P.
DNR congres, Imaging of neuroinfection, Düsseldorf, Germany
23-9-2015
NI
Wattjes, M.P.
1st Naples course on MS, High Field MRI in MS, Naples, Italy
11-12-2015
NI
Wattjes, M.P.
12th ÖGN congres, Neuromuscular Imaging, Graz, Austria Wintersymposium ‘Sleep, cognition and consciousness’ , ‘The role of sleep in children’s observational learning’, Salzburg/Kaprun, Austria Studium Generale Groningen, Neurowetenschappen van creativiteit, Groningen, The Netherlands Studium Generale Maastricht, Eerherstel voor de slaap, Maastricht, The Netherlands Sportmotorik Tagung 2015 - The Athlete's Brain, Sleep improves motor timing, Munchen, Germany
26-3-2015
NI
22 to 25-1-2015
NMH
2-2-2015
NMH
29-10-2015
NMH
5 to 7-3-2015
NMH
Veltman, D.J. Verhage, M. Verhage, M. Verhage, M. Verhage, M. Verhage, M. Verhage, M. Verhage, M. Verhage, M. Verhage, M. Vies, S.M. van der Vrenken, H.
Vrenken, H.
Vrenken, H. Vriend, C. Vries, H.E. de Vries, H.E. de Vries, H.E. de Vries, H.E. de
Vries, T.J. de Wattjes, M.P.
Werf, Y.D. van der Werf, Y.D. van der Werf, Y.D. van der Werf, Y.D. van der
87
Annual Repprt 2015 - Appendices
Investigator Wiel, M.A. van der Wiel, M.A. van der Wiel, M.A. van der Wiel, M.A. van der Wieringen, W.N. van Wieringen, W.N. van Wieringen, W.N. van Windhorst, A.D. Windhorst, A.D. Windhorst, A.D. Windhorst, A.D. Wolf, N.I. Wolf, N.I. Wolf, N.I. Wolf, N.I. Wolf, N.I. Wolf, N.I. Yaqub, M.
Congress, title lecture
Date
OPERRA Workshop: Modelling of pathogenesis, Statistical methods for molecular networks, Munich, Germany Meeting of the European Society for Biobanking, Statistical Methods for Molecular Networks in Cancer, London, UK Latent Gaussian Models conference, Better prediction by use of codata, Trondheim, Norway Statistical Analysis of Massive Genomic Data, How to learn from a lot: Empirical Bayes in Genomics, Evry, France Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB), Ridge estimation of multiple GGMs: simultaneously, and integratively, Napels, Italy European Meeting of Statisticians, Ridge estimation of Gaussian graphical models from high-dimensional data, Amsterdam, The Netherlands IBS-Roes (Joint Meeting of the International Biometric Society (IBS) Austro-Swiss and Italian Regions), Ridge estimation of Gaussian graphical models from high-dimensional, Milan, Italy EANM congress, PET/SPECT imaging of neuroinflammation: the state of art and targets for radiopharmaceuticals, Hamburg, Germany KSRAMP 2015, Carbon-11 chemistry. Why fighting 20 minutes halflife really makes sense, Seoul, Korea Neuroinflammation imaging seminar, Development of neuroinflammation PET tracers , Leuven, Belgium TOPIM2015, PET imaging of neuroinflammation: concepts and developments , Les Houches, France 41. Jahrestagung der Gesellschaft f체r Neurop채diatrie, Neurop채diatrie im Vogelflug, Basel, Switzerland 11th Meeting of the European Paediatric Neurology Society, Differential diagnosis of neurometabolic diseases mimicking neuroinflammation, Vienna, Austria 15 years Center of Childhood White Matter Disorders, Pattern recognition: Application to hypomyelinating disorders and definition of 4H , Amsterdam, The Netherlands 15 years Center of Childhood White Matter Disorders, Hypomyelination of early myelinating structures, Amsterdam, The Netherlands 11th Meeting of the European Society of Magnetic Resonance in Neuropediatrics (ESMRN), Hypomyelination: MR parameters in view of starting treatment trials, Porto, Portugal Annual meeting of the Society for the Study of Inborn Errors in Metabolism (SSIEM), Adult onset leukodystrophy: Differential diagnosis and management, Lyon, France PET tracer pharmacokinetics and data analysis procedures, INMIND, PET tracer pharmacokinetics and data analysis procedures, Amsterdam, The Netherlands
12-1-2015 1-10-2015 17-9-2015 19-11-2015
Program BMHD NMH BMHD NMH BMHD NMH BMHD NMH
10 to 12-9-2015
BMHD NMH
6 to 10-7-2015
BMHD NMH
15 to 1966-2015
BMHD NMH
10-10-2015
BIT
24-4-2015
BIT
17-9-2015
BIT
2-2-2015
BIT
25-4-2015
BMHD
29-5-2015
BMHD
22-10-2015
BMHD
22-10-2015
BMHD
16-5-2015
BMHD
1-9-2015
BMHD
16 to 18-11-2015
BIT
Scientific and public awards and honors/special appointments Investigator
Scientific/public
Name Award Visiting professor, Univ Perugia, Italy
Berg, W.D.J. van de
Scientific
Geurts, J.J.G.
Scientific
Adjunct Professor
Haan, J. de
Public
TEDxAmsterdam Award
Horssen, J. van
Scientific
Visiting Professor
Lammertsma, A.A.
Scientific
ESMI Award
Munck, J.C. de
Scientific
Petzold, A.
scientific
Petzold, A.
scientific
Posthuma, D.
Scientific
IMDI young talent price Award for peer review work Award for peer review work University Research Chair
Scheltens, Ph.
Public
KNAW Board of directors
88
Granted by
Program
Eramus+
ND
Hotchkiss Brain Institute, University of Calgary, Canada TedxAmstedam
ND
University of Hasselt, Belgium European Society of Molecular Imaging ZonMW
NI BIT ND BIT
Publons
NI
Publons
NI
NI
VU/VUMC board
BMHD
KNAW
ND
Annual Report 2015 - Appendices
Investigator
Scientific/public
Name Award
Granted by
Program
Scheltens, Ph.
Scientific Scientific
AE: Academia Europea Nederlandse Vereniging voor Radiologie
ND
Schoonheim, M. Teunissen, C.E.
Scientific
Teunissen, C.E.
Scientific
Teunissen, C.E.
Scientific
Teunissen, C.E.
Scientific
Teunissen, C.E.
Scientific
Vriend, C.
Scientific
Wilhelmus, M.M.M.
Scientific
Academia Europaea Frederik Philipsprijs (2e plaats) Scientific Supervisor Biobank Vumc, Amsterdam Program Director Parelsnoer Institute Board member of the Society for Cerebrospinal Fluid Analysis and Neurochemstry, raised in October 2014. Member of the steering group of the Human Brain Proteome Project co-chair of Global Biomarker Standardization Consortium (GBSC) Prof. Dr. Hans Lakkeprijs 1st prize poster presentation award, Radboud University, Nijmegen
NI
Management Biobank Vumc
ND
Board of Directors Vumc
ND
the Society
ND
the Society
ND
the Society
ND
Parkinson Vereniging
ND
Dutch Pharmacology Society
ND
Organization of congresses and conferences Investigator
Name, congress, location
Date
Program
Berendse, H.W.
Regionale multidisciplinaire scholing Parkinson, Amsterdam, The Netherlands
9-6-2015
ND
12 to 13-32015 10 to 11-122015
ND
1-2-2015
BIT
16-7-2015
ND NI
Berendse, H.W.
Biemond cursus (landelijke nascholing neurologie), Arnhem/Veldhoven, The Netherlands
Boer, J.F. de
Program committee member of "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine" at SPIE Photonics West conference, San Francisco, USA
Dam, A.M.W. van
Symposium at European Glial Meeting, Bilbao, Spain
Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Flier, W.M. van der
NTR-AVERA-Affymetrix meeting, VU, Amsterdam, The Netherlands Genetisch onderzoek en de Sociale Wetenschappen. Sociaal Wetenschappelijke Raad, Amsterdam, The Netherlands KNAW Colloquium: Beyond the Genetics of Aggression; From Clinic to Research and Back, Amsterdam, The Netherlands Wellcome Trust Meeting on Biomarkers in Brain Disorders, Cambridge, UK
19 & 20-012015 30 & 31-012015 22 & 23-102015 1-2-2015
NMH NMH NMH ND BIT BMHD NMH ND
Gunst, M.C.M. de
European Meeting of Statisticians (EMS), Amsterdam, The Netherlands
6 to 10-072015
Hoozemans, J.J.M.
NUBIN conference (co-organizer), Amsterdam, The Netherlands
29-10-2015
Hoozemans, J.J.M.
TN2 conference 2015, Amsterdam, The Netherlands 15 years Center of Childhood White Matter Disorders, Amsterdam, The Netherlands
3-12-2015 22 to 23-102015
Mansvelder, H.D.
Symposium Dutch Neuroscience Meeting, Lunteren, The Netherlands
2-6-2015
Munck, J.C. de
1 to 5-9-2015 20-12-2015
NI
20-10-2015
BMHD
Salomons, G.S.
BACI conference, Utrecht, The Netherlands Nederlandse Neuro-ophthalmology Society (NeNOS)., Amsterdam, The Netherlands Aminoacyl tRNA synthetase conference (international consortium), Amsterdam, The Netherlands Annual worldwide SSIEM conference, Rome, Italy
BIT ND NMH BIT
3 to 6-9-2016
BMHD
Scheltens, Ph.
Dementia Update, Amsterdam, The Netherlands
20-3-2015
ND
Knaap, M.S. van der
Petzold, A. Salomons, G.S.
89
ND BMHD
Annual Repprt 2015 - Appendices
Investigator Someren, E.J.W. van Someren, E.J.W. van Teunissen, C.E. Verhage, M. Wilhelmus, M.M.M. Wolf, N.I.
Name, congress, location Neuroscience 2015, chair Sympoiusm: Disrupted sleep: From moleculaes to cognition, Chicago, USA Chair Symposium at the World Association of Sleep Medicine (WASM) 6th World Congress on Sleep Medicine. The role of sleep and insomnia in stress, emotion regulation and psychiatric symptoms., Seoul, Korea BioMS meeting 2015, organiser , Barcelona, Spain Director Cajal School Advanced Techniques in Synapse Biology, Bordeaux, France 2nd Translational Neuroscience Network: From Mechanisms to Therapy in Neurodegeneration, Amsterdam, Amsterdam, The Netherlands 15 years Center of Childhood White Matter Disorders, Amsterdam, The Netherlands
Date
Program
Oct. 2015
NMH
March 2015
NMH
6-10-2015 10 to 31-102015 3 to 4-122015 21 to 22-102015
NI BMHD ND BMHD
Memberships of scientific committees, editorial boards and civil society advisory bodies Investigator
Membership of
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function
Barkhof, F.
a scientific committee
ISTAART: Alzheimer Imaging Consortium (Committee member)
Barkhof, F.
a civil society advisory body
MS Society UK (MRI management board)
Barkhof, F.
an editorial board
Neurology (Member)
Barkhof, F.
an editorial board
Radiology (Member)
Barkhof, F.
an editorial board
Nederlands Tijdschrift voor Geneeskunde; sectie Radiologie (Section editor)
Barkhof, F.
a civil society advisory body
Brain (Member)
Barkhof, F.
an editorial board
European Radiology (Section editor)
Barkhof, F.
an editorial board
Neuroradiology (member)
Barkhof, F.
an editorial board
Multiple Sclerosis Journal (Member editorial board)
Bartels, M.
an editorial board
Frontiers in Genetics (associate Editor)
Bartels, M.
an editorial board
Frontiers in Psychiatry (associate Editor)
NMH
Bartels, M.
a scientific committee
Behavior Genetics Association (Member)
NMH
Bartels, M.
a scientific committee
NMH
Bartels, M.
a scientific committee
Bartels, M.
a scientific committee
Bartels, M.
a civil society advisory body
Bartels, M.
a scientific committee
European Network for Positive Psychology (ENPP) (Member) International Positive Psychology Association (IPPA) (Member) International Society for Twin Studies (Board member) JongGR committee, part of the Health Council of the Netherlands [Jonge Gezondheidsraad- JongGR commissie] (Member) Dutch Network of Women Professors (LNVH) (Member)
Bartels, M.
a scientific committee
NMH
Bartels, M.
a scientific committee
Bartels, M.
a scientific committee
Bartels, M.
a scientific committee
Bartels, M.
a scientific committee
Nederlandse Vereniging voor Psychonomie (Member) Neurobiology of Mental Health NCA (Member Program Committee ) QENE-QOL (Member) Social Science Genetic Association consortium (Member steering committee Wellbeing) Vereniging voor Vernieuwingsimpuls Onderzoekers (VVViO) (Member)
90
Program BIT ND NI BIT ND NI BIT ND NI BIT ND NI BIT ND NI BIT ND NI BIT ND NI BIT ND NI BIT ND NI NMH
NMH NMH NMH NMH NMH NMH NMH NMH
Annual Report 2015 - Appendices
a scientific committee
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function ZonMw Youth Programming Study (Member Grant Advisory Board) ZonMw Veni MaGW (Member Grant Advisory Board)
NMH
a scientific committee
Advisory Board F1000 Research ()
ND
Berendse, H.W.
a scientific committee
WAR Hersenstichting (Member)
ND
Berendse, H.W.
Monument Discovery Project Assessment Panel (Member)
ND
Berg, W.D.J. van de
a scientific committee a civil society advisory body a scientific committee
Berg, W.D.J. van de
a scientific committee
Berg, W.D.J. van de
a scientific committee
Berg, W.D.J. van de
a scientific committee
Berg, W.D.J. van de
a scientific committee
Berg, W.D.J. van de
a scientific committee
Boellaard, R. Boellaard, R. Boellaard, R.
an editorial board
Eur.J. Med.Phys (Physica Medica) (Associate editor)
BIT
Boellaard, R.
a scientific committee
QIBA FDG PET/CT (Member, contributor)
BIT
Boellaard, R.
a scientific committee
UPICT FDG PET/CT (Member executive board)
BIT
Boellaard, R.
a scientific committee
EANM physics committee (Vice chair, senior advisor)
BIT
Boellaard, R.
NVKF BVT nascholingscie (Secretary, contributor)
BIT
CBORT (NIH P41 grant advisory Board) (Chair)
BIT
Boomsma, D.I.
a scientific committee a civil society advisory body an editorial board
Genes, brain, and behavior (member)
NMH
Boomsma, D.I.
an editorial board
NMH
Boomsma, D.I.
an editorial board
Boomsma, D.I.
an editorial board
Neuropsychiatric Genetics (member) Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) (member) Twin Research and Human Genetics (associate Editor)
Boomsma, D.I.
Boomsma, D.I.
a scientific committee a civil society advisory body a scientific committee
Boomsma, D.I.
a scientific committee
Boomsma, D.I.
a civil society advisory body
Investigator
Membership of
Bartels, M.
a scientific committee
Bartels, M. Beek, J.H.G.M. van
Berendse, H.W.
Boer, J.F. de
Boomsma, D.I.
Program NMH
Parkinson Advies Raad (Member)
ND
International Basal Ganglia Society (Member)
ND
Federation of Dutch Neuroscience organizations (Member) WFN research group on Parkinsonsism and Related disorders (Associate member) Dutch working group on Movement disorders (Member)
ND
ND
an editorial board
Dutch society for Anatomy (Member) Parkinson's and Multiple sclerosis UK Brain Bank (Member of audit panel; member of advisory board) EJNMMIn Physics (Associate editor)
an editorial board
EJNMMI (Associate editor)
BIT
Boomsma, D.I.
a scientific committee
Boomsma, D.I.
a scientific committee
Boomsma, D.I.
a civil society advisory body
ND ND ND BIT
NMH NMH
Huibregtsen prize (for Science and Society) (Member Jury) The Health Council of the Netherlands (Gezondheidsraad) / section Genetics (Member) Steering com. Consortium Individual Development (Member) Social Sciences Council (SWR) of the Royal Academy of Science (Member)
NMH
Nationale Denktank (Raad van Advies)
NMH
Biobanking and Biomolecular Resources Research Infrastructure (BBMRI)-NL (Board member) Biobanking and Biomolecular Resources Research Infrastructure 2 (BBMRI-2) (Board member) Klankbord groep Nationale Wetenschapsagenda (Member)
NMH NMH NMH
NMH NMH NMH
Boomsma, D.I.
a scientific committee
Boomsma, D.I.
a scientific committee
Johannes Ruigrok prize (Koninklijke Hollandsche Maatschappij der Wetenschappen) (Member Jury) “Avond van Wetenschap & Maatschappij� (Board member)
Bot, M.
a scientific committee
BBMRI-NL, BIONIC project (Project manager)
NMH
Cornelisse, L.N.
a scientific committee
Neuroinformatics NL (Member steering committee)
Dam, A.M.W. van
an editorial board
Neuropharmacology (Member)
Dam, A.M.W. van
an editorial board
Brain, Behaviour and Immunity (Member)
Dam, A.M.W. van
an editorial board
ISRN Neurology (Member)
Dam, A.M.W. van
a scientific committee
NCA Neuroinflammation (Member)
Dam, A.M.W. van
a scientific committee
GliaNED (Member)
BMHD ND NI ND NI ND NI ND NI ND NI
91
NMH NMH
Annual Repprt 2015 - Appendices
Investigator
Membership of
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function
Drukarch, B.
an editorial board
International Scholarly Research Notices (Member)
Drukarch, B.
a scientific committee
Research Ethics Committee VUmc (Member)
Flier, W.M. van der
a scientific committee a civil society advisory body
ISTAART (Member advisory council)
ND NI ND NI ND
Parkinson Advies Raad (Member)
ND
Foncke, E.F.
Program
Gerritsen, L.
a scientific committee
Geurts, J.J.G.
an editorial board
Hippocampal Harmonization Protocol project (Research project member, expert Delphi panel) Neurology (Member editorial board)
Geurts, J.J.G.
an editorial board
MSJ (Associate editor)
NI
Geurts, J.J.G.
an editorial board
MS International (Associate editor)
NI
Geurts, J.J.G.
BMC Neurology (Associate editor)
NI
De Jonge Akademie (Member)
NI
Geurts, J.J.G.
an editorial board a civil society advisory body a scientific committee
Society of Neuroscience (Member)
NI
Geurts, J.J.G.
a scientific committee
Dutch federation of Neuroscience (Member)
NI
Geurts, J.J.G.
a scientific committee
European federation of Neuroscience (Member)
NI
Geurts, J.J.G.
a scientific committee
NI
Geurts, J.J.G.
a scientific committee
Geurts, J.J.G.
a scientific committee
Dutch Federation of Anatomists (member) Basis Neuroscience Scientific Review Committie for the Progressice Multipje Sclerosis Alliance (member) MAGNIMS (Member)
Geurts, J.J.G.
a scientific committee
IMSCOGS (Member)
NI
Geurts, J.J.G.
a scientific committee
NI
Geus, E.J.C. de
a scientific committee
Geus, E.J.C. de
a scientific committee a civil society advisory body
Progressive MS Alliance (Member) European Research Council (ERC) (Member Advanced Grant review panel ) LifeKIC (Member of Management Team ) Netherlands Heart Foundation (Member review panel )
NMH
Geurts, J.J.G.
Geus, E.J.C. de
NMH NI
NI NI
NMH NMH
Geus, E.J.C. de
a scientific committee
Geus, E.J.C. de
a scientific committee
Geus, E.J.C. de
a scientific committee
Netherlands Science Organisation NWO-MAGw (Member of several review panels ) Society for Ambulatory Assessment (Executive Board Member ) ZonMW (Member TOP grants review panel )
Geus, J.C.N. de
an editorial board
Mental Health and Physical Activity (member)
NMH
Geus, J.C.N. de
an editorial board
Psychosomatic Medicine (associate Editor)
NMH
Geus, J.C.N. de
an editorial board
Twin Research and Human Genetics (member)
Gunst, M.C.M. de
an editorial board
Statistics Surveys (Associate editor)
Gunst, M.C.M. de
a scientific committee
European Women in Mathematics, Netherlands (Advisory Board member)
Gunst, M.C.M. de
a scientific committee
Van Dantzig National Seminar in Statistics (Advisory Board member and Treasurer)
Gunst, M.C.M. de
a scientific committee
Mathematics Board, Lorentz Centre (Chair)
Gunst, M.C.M. de
a scientific committee
Curatorium Bijzondere Leerstoel Statistics for Genomics (Wiskunde, FEW,VU) (Chair)
Gunst, M.C.M. de
a Scientific Committee
WONDER,the Ducth research school in mathematics (Board member)
Gunst, M.C.M. de
a scientific committee
Netherlands Society of Statistics and Operations Research (Registered Biostatistician-VVS)
Gunst, M.C.M. de
a scientific committee
International Statistical Institute (Elected member )
Heine, V.M.
a scientific committee
PhD Committee Marcin Czepiel (Committee member)
NMH BIT BMHD NMH BIT BMHD NMH BIT BMHD NMH BIT BMHD NMH BIT BMHD NMH BIT BMHD NMH BIT BMHD NMH BIT BMHD NMH BMHD
92
NMH NMH NMH
Annual Report 2015 - Appendices
Investigator
Membership of
Heine, V.M.
a scientific committee
Heuvel, O.A. van den
a scientific committee
Heuvel, O.A. van den
a scientific committee
Heuvel, O.A. van den
a scientific committee
Heuvel, O.A. van den
a scientific committee
Heuvel, O.A. van den
a civil society advisory body
Heuvel, O.A. van den
a civil society advisory body a civil society advisory body a scientific committee
Heuvel, O.A. van den
a scientific committee
Heuvel, O.A. van den
a scientific committee
Hoozemans, J.J.M.
an editorial board
Horssen, J. van
an editorial board
Horssen, J. van
an editorial board
Klumpers, U.H.M.
a scientific committee
Klumpers, U.H.M.
a scientific committee
Heuvel, O.A. van den Heuvel, O.A. van den
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function VIDI VU/VUMC Advisory committee (Committee member) Dutch Society for Psychiatry (NVvP), Committee Scientific Activites (CWA) (Member) Obsessive-compulsive and related disorders research netork (OCRN) in ENCP (Member) Society of Biological Psychiatry (SOBP), Mentorship committee (Member) Society of Biological Psychiatry (SOBP), Program committee (Member) World Health Organisation (WHO), International Advisory Group for the revision of the ICD-10 Mental and Behavioural disorders, Working Group of the Classification of ObsessiveCompulsive and Related disorders (Committee member) Fonds Psychische Gezondheid (Dutch Mental Health Foundation); Raad van Toezicht (Member supervisory board) Patient AdviesRaad (PAR), Parkinson Vereniging (Patient Advisory board (Patient AdviesRaad, secretary)) Dutch Working Group on Movement Disorders (Member) OCD Brain Imaging Consortium (OBIC) (Chair) ENIGMA-Obsessive-Compulsive Disorder (OCD) working group (Chair) Acta Neuropathologica Communications (Editor) Journal of Antioxidants (Member editorial board) BioMed Research International section Immunology (Member editorial board) Dutch Society for Psychiatry (NVvP), Committee Scientific Activities (CWA) (board member) Knowledge center Bipolar Disorders (KenBIS), ROM committee (board member)
Knaap, M.S. van der
a civil society advisory body a scientific committee
Knaap, M.S. van der
a scientific committee
Knaap, M.S. van der
a scientific committee
Knaap, M.S. van der
a scientific committee
Knaap, M.S. van der
a scientific committee
Koellinger, P.D.
an editorial board
Lammertsma, A.A.
a scientific committee
Lammertsma, A.A.
a civil society advisory body
Lammertsma, A.A.
a scientific committee
Lammertsma, A.A.
a scientific committee
Lammertsma, A.A.
a scientific committee
Young Investigator Award Committee, EMIM 2015 (Member)
Lammertsma, A.A.
a scientific committee
Scientific Advisory Board, Center for Integrated Oncology Kรถln Bonn (Member)
Lammertsma, A.A.
an editorial board
International Journal of Molecular Imaging (Ad hoc editor)
Lammertsma, A.A.
an editorial board
Nuklearmedizin (Section editor)
Lammertsma, A.A.
an editorial board
Molecular Imaging and Biology (International associate editor)
Lammertsma, A.A.
an editorial board
Oncology Research and Treatment (Associate editor)
Lammertsma, A.A.
an editorial board
Clinical and Translational Imaging (Consulting editor)
Lammertsma, A.A.
an editorial board
Journal of Cerebral Blood Flow and Metabolism (Member)
Knaap, M.S. van der
Program BMHD NMH NMH NMH NMH NMH NMH NMH NMH NMH NMH ND NI NI NMH NMH
KNAW (member)
BMHD
ERC consolidator grant review committee (member)
BMHD
Jacobus Willemse prijs commissie (member) Winkler medaille commissie, Nederlandse Vereniging voor Neurologie (member) United leukodystrophy Foundation (Member of the Scientific Advisory Committee) Mission Massimo (Member of the Scientific Advisory Committee) Small Business Economics (Associate Editor) NeuroImaging Committee, European Society of Nuclear Medicine (Member) College van Beroep, Stichting Opleiding Klinische Fysica (Member) Werkgroep Stralingsnormen Medisch Onderzoek, Nederlandse Vereniging voor Nucleaire Geneeskunde (Chairman) NCS subcommittee Radiation Doses & Risk Estimation for Medical Diagnostics and Research (Member)
BMHD
93
BMHD BMHD BMHD NMH BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND
Annual Repprt 2015 - Appendices
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function European Journal of Nuclear Medicine and Molecular Imaging (Member) American Journal of Nulcear Medicine and Molecular Imaging (Member)
Investigator
Membership of
Lammertsma, A.A.
an editorial board
Lammertsma, A.A.
an editorial board
Lammertsma, A.A.
an editorial board
Current Medical Imaging Reviews (Member)
Lammertsma, A.A.
an editorial board
BMC Medical Physics (Member)
Lammertsma, A.A.
an editorial board
OA Molecular Oncology (Member)
Lammertsma, A.A.
an editorial board
Journal of Radiology Research and Practice (Member)
Li, K.W.
an editorial board
Amino Acids (Field Editor)
Linkenkaer-Hansen, K.
an editorial board
Frontiers in Physiology (Associate Editor)
Mansvelder, H.D.
an editorial board
PLoS 1 (Academic editor)
Mansvelder, H.D.
an editorial board
Frontiers in Cellular Neuroscience (Reviewing editor)
Mansvelder, H.D.
an editorial board
Frontiers in Synaptic Neuroscience (Associate editor)
Marle, H. van
a scientific committee
Meredith, R.M. Milaneschi, Y.
Program BIT ND BIT ND BIT ND BIT ND BIT ND BIT ND BMHD BMHD BIT ND NMH BIT ND NMH BIT ND NMH
a scientific committee
Dutch Society for Psychiatry (NVvP), Committee Scientific Activities (CWA) (Member) Dutch annual neuroscience meeting (Chair elect)
BMHD
a scientific committee
International Society of Psychiatric Genetics (ISPG) (Member)
NMH
Pattij, T.
an editorial board
Plos ONE (Academic editor)
NMH
Pattij, T.
an editorial board
Frontiers in Behavioral Neuroscience (Reviewing editor)
NMH
Pattij, T.
an editorial board
Frontiers in Pharmacology (Reviewing editor)
NMH
Pattij, T.
a scientific committee
NWO ALW Open (Member)
NMH
Penninx, B.W.J.H.
an editorial board
NMH
Penninx, B.W.J.H.
a scientific committee
Penninx, B.W.J.H.
a scientific committee
Penninx, B.W.J.H.
a scientific committee
Penninx, B.W.J.H.
a scientific committee
Penninx, B.W.J.H.
a scientific committee
Lancet Psychiatry (Review editor) European Psychiatric Association, Psychiatric Epidemiology Section (Board member) American Psychosomatic Medicine Association (Member awards committee) Stiftung Deautsch Depressionhilfe (German Depression Center), Leipzig (Member external advisory committee) Netherlands Scientific Organization (NWO) (Member VIDI review committee) NIAS-Lorentz (Member Advisory Committee)
Penninx, B.W.J.H.
a scientific committee a civil society advisory body
NMH
NMH NMH NMH NMH NMH
Penninx, B.W.J.H.
a scientific committee
Penninx, B.W.J.H. Penninx, B.W.J.H., Milaneschi, Y., Bot, M. Penninx, B.W.J.H., Milaneschi, Y., Peyrot, W.
a scientific committee
Gerontological Society of America (Fellow) Depression Society (Depressievereniging) (Scientific advisory board) Netherlands Study of Depression and Anxiety (Scientific director) BBMRI-NL, BIONIC project (Project member)
a scientific committee
European Moodfood consortium (Project member)
NMH
a scientific committee
Psychiatric Genomics Consortium Major Depression (PGCMDD) group (Project member)
NMH
Penninx, B.W.J.H.
NMH NMH NMH NMH
Peterman, E.J.G.
a scientific committee
Petzold, A.
an editorial board
Nederlandse Vereniging voor Biofysica en Biomedische Technology (Board member) Neuro-Ophthalmology (Member)
Petzold, A.
an editorial board
Multiple Sclerosis International (Associate editor)
NI
Pijnenburg, Y.A.L.
International Society of Frontotemporal Dementias (Member)
ND
nederlands-Vlaamse FTD expertgroep (Chair)
ND
Polderman, T.J.C.
a scientific committee a civil society advisory body a scientific committee
NMH
Posthuma, D.
a scientific committee
Behavior Genetics Association (Information Officer) international OCD GWAS consortium (Member executive board)
Pijnenburg, Y.A.L.
94
BIT NI
BMHD
Annual Report 2015 - Appendices
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function international Tourette’s syndrome GWAS consortium (Member executive board) Granting and evaluation committee VIDI grants - NWO MAGW (Netherlands Scientific Organization) (Member executive board) Granting and evaluation committee ZonMW TOP grants NWO (Netherlands Scientific Organization) (Member executive board) Genetic Cluster Computer (Scientific Director )
Investigator
Membership of
Posthuma, D.
a scientific committee
Posthuma, D.
a scientific committee
Posthuma, D.
a scientific committee
Posthuma, D.
Scientific Director
Posthuma, D.
a scientific committee
Posthuma, D.
an editorial board
Posthuma, D.
an editorial board
Posthuma, D.
a scientific committee
Posthuma, D.
a scientific committee
Posthuma, D.
a scientific committee
Posthuma, D.
a scientific committee
Posthuma, D.
a scientific committee
Rozemuller, A.J.M.
a scientific committee
Rozemuller, A.J.M.
an editorial board
Rozemuller, A.J.M.
a scientific committee
Rozemuller, A.J.M.
a scientific committee
Salomons, G.S.
a scientific committee
Salomons, G.S.
an editorial board
Scheltens, Ph.
Scheltens, Ph.
a scientific committee a civil society advisory body a scientific committee a civil society advisory body a civil society advisory body an editorial board
Scheper, W.
a scientific committee
Scheper, W.
a scientific committee
NWO-ALW VENI committee (Member of selection committee)
Scheper, W.
a scientific committee
Alzheimer Nederland fellowship committee (Member of selection committee)
Scheper, W.
an editorial board
BioMed Research Internationl (Editor)
Scheper, W.
an editorial board
Journal of Neurodegenerative diseases (Editor)
Scheper, W.
a scientific committee
Schmaal, L.
a scientific committee
Smit, J.H.
a scientific committee
Scheltens, Ph. Scheltens, Ph. Scheltens, Ph. Scheltens, Ph.
Smit, J.H.
a scientific committee
Smit, J.H.
a scientific committee
Smit, J.H.
a scientific committee
Smit, J.H.
an editorial board
Smit, J.H.
an editorial board
Smit, J.H.
a scientific committee
Program BMHD BMHD BMHD BMHD
University Evaluation Committee (Member executive board) Frontiers in Genetics - Statistical Genetics and Methodology (Associate editor) Behavior Genetics (Associate editor)
BMHD
TwinLife (Advisory board member) Granting committee ‘Language in Interaction’, Radboud University, Donders Centre for Cognitive Neuroimaging (Member executive board) PGC Data access committee (Chair)
BMHD
IPScenter (Co-founder and member executive board) Complex Trait Genetics Research theme, Neuroscience Amsterdam (Chair) Advisory board Netherlands Brain bank (Evaluation of scientific work before sending tissue) Scientific committee NAN (Advisory function) Advisory board DPUK (Dementia Platform UK; financing system of research) advisory function () RIVM priondiseases (Advice and surveillance) Society for the Study of Inborn Errors of Metabolism (Honorary secretary ) Journal of Inherited Metabolic disase (Communicating editor )
BMHD
French National Plan (Scientific advisory board)
ND
Deltaplan dementia (Vice Chair)
ND
Weston Brain Institute (Member)
ND
PSI (Scientific Director (until 01 june))
ND
HSN (Member RVC (until 01 June))
ND
Alz Dis Assoc Disord (Member) Internationale Stichting Alzheimer Onderzoek (Member of scientific advisory board)
ND BMHD ND BMHD ND BMHD ND BMHD ND BMHD ND BMHD ND NMH
EU-COST action "Proteostasis" (Leader of translational project group and working group leader for protein quality control.) ENIGMA-MDD research group (Chair) Society of longitudinal and Life course Studies (SLLS) (Secretary) BBMRI-NL (Steering group member) Giving in the Netherlands (Member executive board) Amsterdam Study of Anxiety and Depression (AMSTAD) (Project manager) Frontiers in Psychiatry (Associate editor) Journal of Longitudinal and Life Course Studies (Associate editor) ROM in Mental Health (Synquest) (Executive board member and scientific advise councel)
95
BMHD BMHD
BMHD BMHD BMHD ND ND ND ND BMHD BMHD
NMH NMH NMH NMH NMH NMH NMH
Annual Repprt 2015 - Appendices
Investigator
Membership of
Smit, J.H.
a scientific committee
Smit, J.H.
a scientific committee
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function Netherland Study of Depression and Anxiety (NESDA) (Executive board member) EU KP7 Eufori study on filantropy (Executive board member)
Smit, J.H.
a scientific committee
EU AAL programme ecare@home (Executive board member)
NMH
Smit, J.H.
a scientific committee
EU KP7 E-Compared (Executive board member)
NMH
Smit, J.H.
a scientific committee
EU KP7 IBenC (Steering group member and WP leader)
NMH
Smit, J.H.
a scientific committee
EU KP7 Mastermind (Steering group member and WP leader)
NMH
Smit, J.H.
a scientific committee
The NET-QBIC study (Member executive board)
NMH
Smit, J.H.
a scientific committee
BBMRI BIOLINK project (Principal investigator)
NMH
Teunissen, C.E.
a scientific committee
NUBIN (General manager)
NI
Teunissen, C.E.
a scientific committee
BioMS-eu network (General manager)
NI
Teunissen, C.E.
an editorial board
Book: CSF diagnostics in clinical practise. Springer. (Editor)
ND
Teunissen, C.E.
an editorial board
Journal: Special Issue Frontiers in Neuroscience (Editor)
ND
Teunissen, C.E.
an editorial board
ND
Thomaes, K.
a scientific committee
Thomaes, K.
a scientific committee
Thomaes, K.
a scientific committee
Thomaes, K.
a scientific committee
Book: CSF analysis in research. Elsevier. (Editor ) European Society for Traumatic Stress Studies (ESTSS), (Member taskforce neurobiology of traumatic stress) International Society for Traumatic Stress Studies (ISTSS), (deputy for submissions to the clinical/intervention research task) PACO (Programma Advies Commissie Onderzoek)/ RZO (Raad voor civiel-militaire Zorg en Onderzoek) (member) ENIGMA-PTSD group (Project member)
Toonen, R.F.G.
an editorial board
Frontiers in Neuroscience (Associate editor)
Veerhuis, R.
a scientific committee
International Complement Society (Member)
Veerhuis, R.
a scientific committee
European Complement Network (ECN) (Member)
Veerhuis, R.
a scientific committee
Dutch Glia taskforce (Member)
Veltman, D.J.
an editorial board
Veltman, D.J.
a scientific committee
Veltman, D.J.
a scientific committee
Veltman, D.J.
a scientific committee
Verhage, M.
Member editorial board
Frontiers in Psychopathology (Review editor) Network Obsessive Compulsive and Related Disorders, European College of Neuropharmacology () Program committee Spinoza Centre (Chair) NWO/ Netherlands Organisation for Health Research and Development (ZonMw) (Member VIDI review committee)
Program NMH NMH
NMH NMH NMH NMH BMHD ND NMH ND NMH ND NMH NMH NMH NMH NMH
Biology of the Cell (Editor)
BMHD ND
Vies, S.M. van der
a scientific committee
European Association for Chemical and Molecular Sciences (Member executive board)
Vrenken, H.
a scientific committee
ISMRM White Matter Study Group (Secretary (rotating))
Vrenken, H.
a scientific committee
MAGNIMS (Steering Committee Member)
Vrenken, H.
an editorial board
BMC Neurology (Associate Editor)
Vries, H.E. de
a scientific committee
Vries, H.E. de
a scientific committee
Vries, H.E. de
an editorial board
International Brain barriers soceity (Member of the steering committee) Neuroscience Campus Amsterdam (Program leader Neuroinflammation) Fluids and barriers of the CNS (Editorial board member)
Vries, H.E. de
a scientific committee
BBBNedwork (Chair of the steering committee)
Vries, H.E. de
an editorial board
MS international (Editorial board member)
NI
Vries, H.E. de
a scientific committee
NI
Vries, T.J. de
a scientific committee
Vries, T.J. de
a scientific committee
Wamelink, M.
a scientific committee
Glia Workgroup NL (Member of the steering committee) European Behavioural Pharmacology Society (Member of the full committee) GO VENI committee NWO (Member) Erfelijke Stofwisselingsziekten in het Nederlandse taalgebied (Treasurer)
96
NI ND BIT NI ND BIT NI ND BIT NI NI NI NI
NMH NMH BMHD
Annual Report 2015 - Appendices
Investigator
Membership of
Wattjes, M.P.
an editorial board
Name of the - scientific committee; - book/journal; or - civil society advisory body & positon/function Neuroradiology (Member)
Wattjes, M.P.
an editorial board
European Radiology (Member)
NI
Wattjes, M.P.
an editorial board
Journal of Neuroimaging (Member)
NI
Wattjes, M.P.
an editorial board
NI
Wattjes, M.P.
a scientific committee
Frontiers in Neurology (Associate Editor) European Congres of Radiology (Member Scientific committee Neuroradiology)
Werf, Y.D. van der
a scientific committee
Hersenstimulatie stichting (Founding member, member executive board)
Werf, Y.D. van der
a scientific committee
scientific advisory board NACB (Normal aging brain collection) (Member)
Werf, Y.D. van der
a civil society advisory body
jury Akademie van Kunsten, new members 2015, KNAW (Member)
Werf, Y.D. van der
a civil society advisory body
Jury European Researchers Night (Member)
Werf, Y.D. van der
an editorial board
Human Brain Mapping (Associate Editor)
Werf, Y.D. van der
a civil society advisory body
MS Foundation scientific advisory board (Member)
Wiel, M.A. van der
an editorial board
STAT (Associate Editor)
Wiel, M.A. van der
a civil society advisory body
Committee appointed by the UvA for integrity research on a former employee (Co-writer of the public report)
Wieringen, W.N. van
an editorial board
Heliyon (Editorial advisor)
Wilhelmus, M.M.M.
an editorial board
The International Journal of Clinical and Experimental Pathology (Editorial board member)
Wilhelmus, M.M.M. Wilhelmus, M.M.M.
a civil society advisory body a civil society advisory body
Program NI
NI BIT ND NMH BIT ND NMH BIT ND NMH BIT ND NMH BIT ND NMH BIT ND NMH BMHD NMH BMHD NMH BMHD NMH ND
Scientific Advisory Board (Member)
ND
PharmaPanel (Member)
ND
WebmedCentral Neurosciences Advisory Board (Editorial board member) NCA neurodegeneration committee (Board member)
Wilhelmus, M.M.M.
a scientific committee
Wilhelmus, M.M.M.
a scientific committee
ND
Wilhelmus, M.M.M.
an editorial board
The Scientific World Journal (Editorial board member)
ND
Wilhelmus, M.M.M.
a scientific committee
Animal Welfare Body VU/VUmc (Member)
ND
Wilhelmus, M.M.M.
an editorial board
Journal of Alzheimer's Disease (Associate editor)
ND
Windhorst, A.D.
an editorial board
Nuclear Medicine & Biology (associate editor)
BIT
Windhorst, A.D.
an editorial board
J. Labelled Compnd & Radiopharm (editor)
BIT
Windhorst, A.D.
an editorial board
Frontiers in Nuclear Medicine (advisor)
BIT
ND
Windhorst, A.D.
an editorial board
Current radiopharmaceuticals (advisor)
BIT
Wolf, N.I.
an editorial board
BMHD
Wolf, N.I.
an editorial board
Wolf, N.I.
an editorial board a civil society advisory body
Neuropediatrics (Editor) Journal of Inherited Metabolic Disease (Communicating Editor) Neurology (Member of the Editorial Board) Orphanet Nederland (Member of the Scientific Advisory Committee) European Leukodystrophy Association (Member of the Scientific Advisory Committee) Mission Massimo (Member of the Scientific Advisory Committee)
Wolf, N.I. Wolf, N.I.
a scientific committee
Wolf, N.I.
a scientific committee
97
BMHD BMHD BMHD BMHD BMHD
Annual Repprt 2015 - Appendices
Appendix 5: a) Demonstrable use of research products by peers and by societal groups b) Research products for peers and societal target groups and outreach activities a. Demonstrable use of research products by peers and by societal groups (Inter)national (non-)academic collaboration *Type of collaboration: A: Use of datasets, software tools, etc. by peers; B: Use of research facilities by peers; C: Use of research facilities by societal groups; D: Other use of products; E: Use of research facilities and sharing of data. Abbreviatons: BIT: Brain Imaging Technology; BMHD: Brain Mechanisms in Health & Disease; ND: Neurodegeneration; NI: Neuroinflammation; NMH: Neurobiology of Mental Health Investigator (between brackets other investigators involved) sAbbink, T.E.M. (Altelaar, A.F.M., Penning R.) Berckel, B.N.M. van (Wit, L. de) Berckel, B.N.M. van (Mark van Buchem (UMCL)) Berendse, H.W. (Foncke, E.F.) Berendse, H.W. (Scheltens, Ph., Foncke, E.F., Heuvel, O.A. van den)
Type of collaborration*
Short description of the used product
External collaborator (research unit or societal group)
B
Mass spectrometry analyses AHA-SILAC
University of Utrecht, The Netherlands
BMHD
B
PET facility
RS. Kahn, Utrecht, The Netherlands
BIT ND
B
PET facility
M.Vernooij, Rotterdam, The Netherlands
EDAN
BIT ND
A
Multicenter clinical trial
Dr. Rob de Bie, AMC, Amsterdam, The Netherlands
CHEVAL
ND
A
Multicenter observational study
Prof.dr. Iris Sommer, UMCU, Utrecht, The Netherlands
Understandig hallucinations
ND
Berendse, H.W.
D
Olfactory test
Prof.dr. Richard Doty, Univ. Pennsylvania, Philadelphia, USA
ND
A
Sharing of clinical and imaging data
Prof.dr. Jan Booij, AMC, Amsterdam, The Netherlands
ND
A
Sharing of datasets
Prof.dr. Peter Heutink, University of Tubingen, Germany
ND
A
Sharing of datasets
Prof.dr. Dorly Deeg, Vumc, The Netherlands
Berendse, H.W. (Heuvel, O.A. van den) Berendse, H.W. (Berg, W.D.J. van de, Dijk, K.D. van) Berendse, H.W.
Berendse, H.W. (Foncke, E.F., Dijk, K.D. van)
A
Sharing of datasets within consortium
Berg, W.D.J. van de (Berendse, H.W, Rozemuller, A.J.M.)
D
Brain tissue samples, lab experiments, data analysis
Berg, W.D.J. van de
B
Brain tissue samples, lab experiments, data analysis
Prof.dr. Daniela Berg, University of Tubingen, Germany
Markus Britschgi, PI Neuroscience Discovery; F. Hoffman-La Roche, Neuroscience Discovery; Roche Innovation Center Basel, Switzerland Henning Stahlberg, PI, C-CINA, Center for cellular imaging and nano-analytics, Basel, Switzerland
98
Name of the consortium / research network
Program
LASA
ND
Harmonization of biomarker assessment in longitudinal cohort studies in Parkinson’s disease
ND
ND
ND
Annual Report 2015 - Appendices
Investigator (between brackets other investigators involved) Berg, W.D.J. van de (Lemstra, E., Teunissen, C.E., Jimenez, C.R.) Berg, W.D.J. van de (Jimenez, C.R., Teunissen, C.E.) Berg, W.D.J. van de (Angela Ingrassia, A.) Berg, W.D.J. van de (Geurts, J.J.G., Rozemuller, A.J.M.)
Type of collaborration*
Short description of the used product
B
Identification of CSF and tissue biomarkers for DLB
A
Identification of CSF biomarkers for Parkinson's disease
B
Lab facility, brain tissue
A
Normal aging brain collection Amsterdam; postmortem imaging
Berg, W.D.J. van de (Berendse, H.W)
A
SAharing datasets, data analysis
Berg, W.D.J. van de (Rozemuller, A.J.M.)
A
SAharing datasets, data analysis
Berg, W.D.J. van de (Berendse, H.W)
A
Sharing datasets, brain tissue and CSF analysis
Boellaard, R. (Yaqub, M.)
B
Boellaard, R. (Lammertsma, A.A.) Boellaard, R. (Lammertsma, A.A.)
A A
Boellaard, R.
A
Boellaard, R.
A
Boellaard, R.
A
Boellaard, R. (Velden, F. van) Boellaard, R. () Comijs, H.C., Dols, A., Exel, E. van, Stek, M.L., Rhebergen, D. ()
Collecting data
Sharing data and analysis tools Sharing data and analysis tools Sharing of data and analysis SW tools for quantitative analysis of PET/CT studies SW tools for quantitative analysis of PET/CT studies
External collaborator (research unit or societal group) Frank-Jan de Jong; dr. Leonie Vergouw; dept Neurologie, ErasmusMC, Rotterdam, The Netherlands Davide Chiasserini, Prof. L. Parnetti, University of Perugia, Italy Marie-Christine Chartier-Harlin; Prof in Genetics, Univ Lille, INSERM, Univ Lille, France Louise van de Weerd and Mark van Buchem, Dept of Radiology, LUMC, Leiden, The Netherlands Prof. L. Parnetti; Prof. T. Beccari; dept Neurology, Univ Perugia, University of Perugia, Italy Peter Heutink, Thomas Gasser, Univ Tubingen, DZNE, Tubingen, Germany Omar El-Agnaf, Univ Qatar, Qatar, Univ of Qatar, Doha, Qatar Univ.Leipzig, Leipzig, Vienna, Essen, Zurich, Germany, Austria, Germany, Switzerland University of Leiden, Leiden, The Netherlands Academic Medical Center, Amsterdam, The Netherlands MAASTRO Clinic, Maastricht, The Netherlands
Name of the consortium / research network
Program
ND
ND ND ND ND ND ND Collaboration between Universities of Leipzig, Essen, Vienna, Zurich, Amsterdam (Vumc)
BIT
BIT BIT BIT
University of Cologne, University of Cologne, Germany
BIT
University Hasselt, University Hasselt, Belgium
BIT
University of Leuven, University of Leuven, Belgium EARL, Vienna, Austria
A
Use of datasets
A
Use of QC software
A
Research cooperation ECT (RespECT)
Dam, A.M.W. van
B
Antibodies
Dam, A.M.W. van
A
Collaborative techniques
Dam, A.M.W. van
B
Glial cells
Dam, A.M.W. van
B
LHC techniques
Dam, A.M.W. van
B
Oligodendrocytes
Dam, A.M.W. van, Drukarch, B. (Wilhelmus, M.M.M.)
B
Animal and cell models
dr. M. Griffin, Aston Univ. Birmingham, UK
Marie Curie ITN network Transpath
ND NI
Dept. Biological Psychology (All)
D
Building Network and sharing knowledge and data Position Paper 1 and 2, Review Paper on Genes and Quality of Life
Mayo Clinic, Rochester, USA, Amsterdam Medical Centre, USA
GeneQOL (Genetic Research inot Quality of Life)
NMH
Sienaart/Broukaert, Universiteit Leuven, Parnassia, Leuven, Belgium
BIT EANM res.ltd
BIT
RespECT
NMH
Prof.dr. T. Johnson, UCB Pharma, Slough, UK Prof. Dr. L. Watkins, Univ. Colorado at Boulder, Boulder, USA Dr. A. Korosi, SILS-UvA, Amsterdam, The Netherlands Dr. J. Bauer, Brain Institute Vienna, Austria Dr. W. Baron, UMCG Groningen, The Netherlands
99
ND NI ND NI ND NI ND NI ND NI
Annual Repprt 2015 - Appendices
Investigator (between brackets other investigators involved)
Dept. Biological Psychology (All)
Type of collaborration*
D
External collaborator (research unit or societal group)
Program
Development and management of a multidisciplinary infrastructure that can compare and merge results from studies, biobanks, research databases and other similar health and social research infrastructures
Name of the consortium / research network
McGill University, Montreal, Canada
P3G (Public Population Project in Genomics and Society)
NMH
Short description of the used product
Dept. Biological Psychology (All)
A
Sharing of dataset within the consortium
University of Oxford, Oxford, UK
Dept. Biological Psychology (All)
A
Sharing of dataset within the consortium
Leiden University Medical Center, Leiden, The Netherlands
Dept. Biological Psychology (All)
A
Sharing of dataset within the consortium
Leiden University Medical Center, Leiden, The Netherlands
Dept. Biological Psychology (All)
A
Sharing of dataset within the consortium
Leiden University Medical Center, The Netherlands
Dept. Biological Psychology (All)
A
Sharing of dataset within the consortium
University College London, London, UK
Dept. Biological Psychology (All)
D
Sharing of dataset within the consortium
Cornell University, Univeristy of Amsterdam, New York, USA
Dept. Biological Psychology (All)
A
Sharing of dataset within the consortium
Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All) Dept. Biological Psychology (All)
A A A A A A A A
Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium
Institute of Metabolic Science, Cambridge University, Cambridge, UK Erasmus MC, Rotterdam, The Netherlands Erasmus MC, Rotterdam, The Netherlands Institute of Epidemiology II Helmholtz Zentrum, M端nchen, Germany
MAGIC (the Meta-Analyses of Glucose and Insulin-related traits Consortium) BBMRI-NL (Biobanking and Biomolecular Research Infrastructure the Netherlands) GONL (Genome of the Netherlands) BIOS (Biobankbased Integrative Omics Studies) consortium (EURO)DISCOT WIN (European Discordant Twin) consortium SSGAC (Social Science Genetic Associastion Consortium)
NMH
NMH
NMH
NMH
NMH
NMH
CHARGEReprogen
NMH
CHARGE-Lipids
NMH
CHARGEHaemogen
NMH
CHARGEFibrinogen
NMH
UCLA (USA), Los Angeles , USA
ENIGMA consortium
NMH
BROAD Inst, Boston, USA
PGC
NMH
EAGLE
NMH
EGG
NMH
MAGNETIC
NMH
EUR, Rotterdam, The Netherlands EUR, Rotterdam, The Netherlands University of Oulu, Oulu , Finland
A
Sharing of results for meta-analyses (SNP & smoking & other phenotypes)
Bristol University, Bristol, UK
A
Sharing results of GWA for meta-analyses
Harvard School of Public Health, Boston, USA
100
CARTA (Causal Analysis Research in Tobacco and Alcohol ) Coffee Consortium
NMH
NMH
Annual Report 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Short description of the used product
External collaborator (research unit or societal group)
Dept. Biological Psychology (All)
D
Sharing results of GWA for meta-analyses
University of Pennsylvania, Philadelphia, USA
D
Animal model and animal tissue
dr. S. Schreiber, Univ Magdeburg, Germany
ND NI
A
Research data on chemical entities
dr. R. Pasternack, Zedira GMbH Darmstadt, Germany
ND NI
prof. Finch, University of Southern California (USC), Davis School of Gerontology, Los Angeles, USA
NMH
Colton Lab, dr. Vitek, Durham, USA
NMH
Karolinska Institute, Medical University, Stockholm, Sweden
NMH
U Calgary, Calgary, Canada
NI
Drukarch, B. (Wilhelmus, M.M.M.) Drukarch, B. (Wilhelmus, M.M.M.)
Exel, E. van
A
Exel, E. van
A
Gerritsen, L
A
Geurts, J.J.G. (Schenk, G., Klaver, R.)
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Geurts, J.J.G.
A
Analyzing data on beneficial early life effects of APOEgenotype in rural Africa, showing that APOE-ξ4 leads to increased fertility Joint research: apoE increasing therapy in Alzheimer’s disease Research projects with several people
Name of the consortium / research network ICE (Insomnia, Chronotype and sleep EEG) consortium
UCL Institute of Neurology, London, UK UCL National Hospital for Neurology and Neurosurgery, London, UK Haukeland, Bergen, Norway
Heine, V.M. (Verhage, M.)
Use of multi electrode array technology rTMS-MRI study regulation of craving in alcohol addiction
B
Heuvel, O.A. van den
A
Heuvel, O.A. van den
A
Heuvel, O.A. van den
A
Heuvel, O.A. van den
A
Heuvel, O.A. van den
A
MRI-study emotional memory and eyemovements in PTSD
Heuvel, O.A. van den
A
MRI-study emotionregulation in uni- and bipolar depression
Brain Bank (NBB-Psy), consortium on postmortem in psychiatry Classification (DSM-5/ ICD-11) and data sharing (OBIC/ENIGMA-OCD) MRI study: family study in OCD and MRI-MRS study in OCD/Tourette
AMC dept. Of Psychiatry, prof. dr. A.E. Goudriaan, Amsterdam, The Netherlands Netherlands Institute of Neurosciences (NIN), dr. I. Huitenga, Amsterdam, The Netherlands Cape town University, prof. D.J. Stein (and prof. dr. C. Lochner), Cape town, South Africa University of Utrecht (UU), dr. D.C. Cath, Utrecht, The Netherlands University of Utrecht (UU),prof. Engelhart,prof. van der Hout, dr.Sybrandi , Utrecht, The Netherlands AMC dept. Of Psychiatry, Amsterdam, The Netherlands
101
NMH
NI NI NI
Stanford, USA Dept. of Pathology, AMC, Amsterdam, The Netherlands Imperial College London, London, UK Dept. of Radiology UMC, Utrecht, The Netherlands Cleveland Clinic, Cleveland, USA University of Buffalo, School of Medicine and Biomedical sciences, Buffalo, USA Kessler Foundation, New Jersey, USA Cardiff University, Cardiff, UK
Program
NI NI NI NI NI NI NI CognitionNet
BMHD NMH
NMH
NMH NMH
NMH
NMH
Annual Repprt 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Short description of the used product
External collaborator (research unit or societal group)
Heuvel, O.A. van den
A
Multicenter study
Bronowski Institute / Massachusetts General Hospital/Austin Hospital, Melbourne/ Boston / Salt Lake City, Australia / USA
Heuvel, O.A. van den
A
Multicenter study
USA
NMH
Heuvel, O.A. van den
A
Multicenter study: Longitudinal study of brain development in children in relation to OCD symptoms
Parkinson Progression Markers Initiative (PPMI)
Erasmus MC, prof. F.C. Verhulst, prof. dr. H. Tiemeier, dr. T. White, Rotterdam, The Netherlands
Generation R cohort
NMH
Heuvel, O.A. van den
A
Neuroimaging in OCD
Heuvel, O.A. van den
A
Neuroimaging in OCD
Heuvel, O.A. van den
A
research on OCD symptom dimensions
Heuvel, O.A. van den
A
Heuvel, O.A. van den
A
Heuvel, O.A. van den
A
Heuvel, O.A. van den (Veltman, D.J.)
A
Sharing data for megaanalysis
OBIC
NMH
Heuvel, O.A. van den (Schmaal, L., Veltman, D.J.)
OCD Brain Imaging Consortium (OBIC) with 7 institutes worldwide, The Netherlands
A
Sharing data for metaand mega-analysis
ENIGMA-OCD (26 institutes worldwide), Los Angeles, USA
ENIGMA
NMH
Heuvel, O.A. van den
A
Sharing of dataset (raw MRI scans) within the world-wide consortium for mega-analysis
Many researchers from all over the world, Barcelona, London, Seoul, Kyoto, Sao Paulo, Cape Town
Heuvel, O.A. van den
A
Sharing of dataset . ENIGMA: Enhancing Neuro Imaging Genetics Through Meta-analysis.
More than 100 institutions worldwide, including 25 OCD sites
Heuvel, O.A. van den, Veltman, D.J.
D
Interdiciplinary training network for Tourette Syndrome
Marie Curie Initial Training Networks Network within the European College in Neuropsychopharmacology (ECNP)
Shared research: Imaging-genetics in pediatric OCD Shared research: Neuroimaging on effects of intensive CBT treatment program Shared research: Neuroimaging on effects of treatment in child OCD
Heuvel, O.A. van den, Veltman, D.J.
A
Research network
Heuvel, O.A. van den, Veltman, D.J.
A
Research network
Heuvel, O.A. van den, Vriend, C.
A
Multicenter study
Name of the consortium / research network
Program
NMH
Bellvitge Hospital, the group of prof. J. Menchon (and dr. C. Soriano-Mas, dr. P. Alonso, dr. N. Cardoner): , Barcelona, Spain Columbia University New York, Prof.dr. H.B. Simpson / dr. R. Marsh, New York City, USA Karolinska Institute, Stockholm, Sweden, dr. D. Mataix-Cols, Stockholm, Sweden University of British Columbia, prof.dr. S.E. Stewart, Vancouver, Canada
NMH
NMH NMH NMH
University of Bergen. prof.dr. G. Kvale / dr. B. Hansen, Bergen, Norway
NMH
University of Copenhagen: prof.dr. K. von Plessen, Copenhagen, Denmark
NMH
International College of Obsessive-Compulsive Spectrumdisorders (ICOCS) 7 UMC’s NL: HW. Berendse / JJ. Van Hilten / B. Bloem / T. van Laar / R. de Bie / A. Boon / B. Post / A. Leentjens / H. Marinus, The Netherlands
102
OCD Brain Imaging Consortium (OBIC) ENIGMAObsessiveCompulsive Disorder (OCD) working group
NMH
NMH
NMH ObsessiveCompulsive and Related Disorders research Network (OCRN)
NMH
NMH Netherlands Parkinson Cohort
NMH
Annual Report 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Holstege, H.
Short description of the used product
External collaborator (research unit or societal group)
D
Biomaterials (blood samples)
LUMC, Leiden, The Netherlands
Horssen, J. van (Amor, S.)
D
Antibodies
Dr. H. Perron, Geneva, Switserland
Horssen, J. van
D
Antibodies
Prof. Pellerin, Lausanne, Switserland
Horssen, J. van
D
CNS samples
Prof. Reynolds, London, UK
Horssen, J. van
D
CNS samples
Horssen, J. van
D
CNS tissue
Horssen, J. van (Teunissen, C.E., Killestein, J.)
D
CSF samples
Hulst, H.E.
A
Use of MRI scans
Hulst, H.E.
A
Use of MRI scans
Knaap, M.S. van der (Wolf, N.I.)
A
Knaap, M.S. van der
A
Next Generation Sequencing / Whole Genome Sequencing Sharing of dataset within the consortium
Prof. B. 't Hart, BPRC, Leiden, The Netherlands Prof. Lassmann, University of Vienna, Austria
Geneuro (pharmaceutical company) University of Lausanne Progressive MS Alliance Network
A. Vanderver, Childrens National Medical Center, Washington, USA, Washington DC, USA
Knaap, M.S. van der, Abbink, T.E.M. ()
D
Expertise/Advice/Consul tation
Knaap, M.S. van der, Abbink, T.E.M.
B
Glycomics facility
B
Use of gene editing technology
Zurich University, Zurich, Switzerland
B
Use of reprogramming technology
Knaap, M.S. van der, Heine, V.M.
B
Use of transplantation technology
Knaap, M.S. van der, Heine, V.M.
B
Sharing of dataset / functional tests
Knaap, M.S. van der, Salomons, G.S., Wolf, N.I. (Mendes, M.I.)
Wurzburg University, Wurzburg, Germany Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, UCSF, San Francisco, USA A. Vanderver, Childrens National Medical Center, Washington, USA, Washington DC, USA
B
Sharing of dataset / functional tests
Knaap, M.S. van der, Salomons, G.S., Wolf, N.I. (Mendes, M.I.)
B
Sharing of dataset / functional tests
Kock, C.P.J. de (Das, S.)
A
Sharing of dataset with collaborator
Kock, C.P.J. de ()
A
Sharing of dataset with collaborator
C.G. Proud, South Australian Health & Medical Research Institute, Adelaide, Australia D. Lefeber, Radboud University Medical Center, Nijmegen, The Netherlands
G. Bernard, McGill University, Montral, Canada, Montreal, Canada C. Simons/ E. Wolvetang, Dept. of Genetics / Australian Institute for Bioengineering and Nanotechnology Queensland University, Queensland, St Lucia , Australia Institute of Neuroscience TU M端nchen, M端nchen, Germany Max Planck Institute for Biological Cybernetics, Gottingen, Germany
103
NI NI NI
NI NI NI BMHD
S. Blaser, Toronto, Canada
Sharing of dataset within the consortium
BMHD ND
NI
University of Buffalo, School of Medicine and Biomedical sciences, Buffalo, USA Kessler Foundation, New Jersey, USA C. Simons, Dept. of Genetics, Queensland University, Queensland, St Lucia, Australia
A
Program
NI
Prof. F. Piehl, Karolinska Institute, Stockholm, Sweden
Knaap, M.S. van der (Wolf, N.I.)
Knaap, M.S. van der, Abbink, T.E.M., Bugiani, M. Knaap, M.S. van der, Heine, V.M.
Name of the consortium / research network
BMHD GLIA (Global Leukodystrophy Initiative Association)
BMHD
BMHD BMHD Erare
BMHD
Erare
BMHD BMHD
tRNA synthetase consortium
BMHD
tRNA synthetase consortium
BMHD
tRNA synthetase consortium
BMHD
BMHD BMHD
Annual Repprt 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Koellinger, P.D. (Posthuma, D.)
A
Koellinger, P.D. (Posthuma, D.)
B
Short description of the used product GWAS meta-analyses results are made publically available and used by many groups from around the globe IT infrastructure of the group is used by external collaborators within the Social Science Genetic Association Consortium (SSGAC)
A
Sharing of data and software code with researchers
Koellinger, P.D.
A
Sharing of data, software code, and GWAS results within the consortium
Lammertsma, A.A. (Boellaard, R., Yaqub, M., Berckel, B.N.M. van)
A
Sharing data and analysis tools
Li, K.W. (Smit, A.B.)
B
Koellinger, P.D.
Li, K.W. (Smit, A.B.)
B
Li, K.W.
B
Li, K.W. (Smit, A.B.)
B
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
Linkenkaer-Hansen, K.
A
use of mass spectometer for proteomics analysis use of mass spectometer for proteomics analysis use of mass spectometer for proteomics analysis use of mass spectometer for proteomics analysis Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools Amsterdam RestingState Questionnaire (ARSQ) and supporting tools
External collaborator (research unit or societal group)
Geneticists, medical researchers, social scientists
New York University, New York, USA Erasmus University Rotterdam Institute for Behavior and Biology (EURIBEB), Rotterdam, The Netherlands
Name of the consortium / research network Social Science Genetic Association Consortium (SSGAC) Social Science Genetic Association Consortium (SSGAC)
Program
NMH
NMH
NMH
Oxford University, Oxford, UK
Social Science Genetic Association Consortium (SSGAC)
NMH
University of Münster, Münster, Germany + many other countries
INMiND (FP7)
BIT ND
KU Leuven, Leuven, Belgium University of Coimbra, Coimbra, Portugal Tel Aviv University, Tel Aviv , Israel Erasmus Medical Center, Rotterdam, The Netherlands The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Aarhus, Denmark
BMHD BMHD BMHD BMHD
BMHD
UC San Diego Healthcare System, San Diego, USA
BMHD
Massachusets General Hospital (MGH), Boston, USA
BMHD
University of Chieti-Pescara, Chiete, Italy
BMHD
Indiana University Bloomington , Bloomington, USA
BMHD
University of Zurich, Psychological Institute, Neuroplasticity and Learning in the Healthy Aging Brain, Zurich, Switzerland
BMHD
The Pennsylvania State University, Pennsylvania, USA
BMHD
Tens of other labs… those listed above were newcomers from 2015
BMHD
104
Annual Report 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Short description of the used product
External collaborator (research unit or societal group) National Institute on Aging (NIH), Longitudinal Studies Section, Translational Gerontology Branch, Baltimore, USA
Milaneschi, Y
A
Data management on the clinical trial on the effect of uric acid on oxidative stress, joint analysis
Milaneschi, Y
A
Joint analysis/publications, methodology advisor
Milaneschi, Y
A
Use of their data, joint analysis
Milaneschi, Y
A
Munck, J.C. de (Kwakkel, G.)
A
Pattij, T. (Van den Heuvel, O.A. van den; Veltman, D.J.)
D
Pennenx, B.W.J.H.
A
Pennenx, B.W.J.H.
A
Pennenx, B.W.J.H.
A
Pennenx, B.W.J.H., Milaneschi, Y. Penninx, B.W.J.H., Bot, M., Paans, M., Gibson-Smit, D. Penninx, B.W.J.H., Bot, M., Vogelzangs, N., Lamers, F. Penninx, B.W.J.H., Exel, E. van Penninx, B.W.J.H., Peyrot, W., Boomsma, D.I.
Use of their data, joint analysis/publications, methodology advisor Sharing EEG data and data processing software Research network for scientific collaboration, funding, and creation of strong consortia Joint research psyche & soma Research network: Chinadep project, epidemiology Research network: MDD in China and other continents
A
University of Genova, department of Internal Medicine, dr. M Canepa, dr. P Ameri, Genova, Italy Centre of Psychiatric Epidemiology and Psychopathology, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland
Name of the consortium / research network
Program
NMH
NMH
Colaus/Psycola us Study
NMH
Dr S Bandinelli, Florence, Italy
InCHIANTI Study
NMH
TU Delft, The Netherlands
4D EEG
BIT
University of Hertfordshire, Hatfield, United Kingdom
Obsessive Compulsive and Related Disorders Network (OCRN)
NMH
Otte, Charité, Berlin, Germany
NMH
University of Oxford (Jonathan Flint), Oxford, UK
NMH
Yihan Li MSc, Prof.dr. J. Flint, Prof.dr. K. Kendler
CONVERGE
NIA (National Institute on Aging), Longitudinal Studies Section, Clinical Research Branch (Luigi Ferrucci, Jack Guralnik), Bethesda, USA
NMH
MooDFOOD consortium
A
Research network
A
Proteomic analyses of NESDA data
D
Expert/consult/advisor late-life depression
A
Joint research genetics
Queensland University, Queensland, Australia
NMH
Penninx, B.W.J.H., Smit, J.H.
A
GAIN GWAS for MDD: Genome Wide Scan made in the USA of genetic material of NESDA and NTR
National Institute of Mental Health, National Institutes of Health. University of NorthCarolina (Prof. P.Sullivan), Chapel Hill, USA
NMH
Penninx, B.W.J.H., Smit, J.H., Boomsma, D.I.
A
Collaborative project, genotyping of NESDA data (and NTR)
Rutgers University, New Jersey (A. Brooks, PhD; J. Tischfeld, PhD) , New Jersey, USA
A
Joint research genetics
Harvard (Perlis), Cambridge, USA
A
Research network GWAS (Genome Wide Scan)
A
BIONIC
Penninx, B.W.J.H., Smit, J.H., Boomsma, D.I. Penninx, B.W.J.H., Smit, J.H., Boomsma, D.I. Penninx, B.W.J.H., Smit, J.H., Bot, M., Boomsma, D.I.
14 partners throughout Europe
NMH
University of Cambridge; Myriad RBM, dr. M. Chan Prof.dr. S. Bahn, Cambridge, UK UCSF (Kristine Yaffe), San Fransisco, USA
King’s College London/IoP (McGuffin, Lewis, Breen), London, UK BBMRI-NL (PI’s of various Dutch cohorts), The Netherlands, Australia, UK, Denmark
105
NMH NMH NMH
GODOT (Gene expression profile in depression)
NMH
NMH NMH BBMRI-NL : BIONIC
NMH
Annual Repprt 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Penninx, B.W.J.H., Smit, J.H., Gaspersz, R.
Short description of the used product
External collaborator (research unit or societal group)
A
Anxious depression & Inflammation projects, joint research project with NESDA
Janssen Pharamceutics, USA
A
Metabolomics research project
D
Expert/consult/advisor on biological aging, telomere lenght
Peterman, E.J.G.
A
Petzold, A. (please see http://www.imsvisu al.com)
Penninx, B.W.J.H., Smiy, J.H., Bot, M., Boomsma, D.I. Penninx, B.W.J.H., Verhoeven, J., Revesz, R.
BBMRI-NL (PI’s of various Dutch cohorts), Various, Oulu, The Netherlands, Finland
Name of the consortium / research network
Program
NMH BBMRI-NL Rainbow project 4
NMH
UCSF, (Jue Lin, Elissa Epel, Owen Wolkowitz):, San Fransisco, USA
NMH
C. elegans strains
Alex Dammermann, Vienna, Austria
BIT
A
Sharing of ocular imaging and clinical data within the consortium
John Hopkins University, Baltimore, USA, USA
Polderman, T.J.C. (Posthuma, D.)
A
Sharing of dataset within consortium
A. Agrawal, Saint Louis, USA
Polderman, T.J.C. (Posthuma, D.)
A
Sharing of dataset within consortium
P. Sullivan, North Carolina, Chapell Hill, USA
Posthuma, D. (Polderman, T.J.C.)
A
Sharing of dataset within the consortium
Patrick F Sullivan et al., Chapel Hill, USA
Posthuma, D. (Polderman, T.J.C.)
A
Sharing of dataset within the consortium
Scott Vrieze, Michigan, USA
Sharing of dataset within the consortium Sharing of dataset within the consortium Sharing of dataset within the consortium
Sita Vermeulen, Nijmegen, The Netherlands Eske Derks, Amsterdam, The Netherlands YGEN consortium, International, The Netherlands
D
Diagnostics on brains for Netherlands brainbank
B
Posthuma, D. (Polderman, T.J.C.) Posthuma, D. (Polderman, T.J.C.) Posthuma, D. (Polderman, T.J.C.) Rozemuller, A.J.M. (Bugiani, M., Valk, P. van der, Voorn, Pl van der for autopsies) Rozemuller, A.J.M. (Hoozemans, J.J.M., Smit, A.B.) Rozemuller, A.J.M. (Hoozemans, J.J.M., IXA, 2 technicians) Rozemuller, A.J.M. (Berg, W.D.J. van de (ANW, VUMC)) Salomons, G.S. (M. Wamelink, E.A. Struys, D. Smith, M. I. Mendes Wamelink, M., Struys, E.A., Smith, D., Mendes, M.I.)
A A A
B B
IMSVISUAL Psychiatric Genetics Consortium; Alcohol Psychiatric Genetics Consortium; Controls Psychiatric Genetics Consortium GWAS & Sequencing Consortium of Alcohol and Nicotine use (GSCAN) BBMRI-Exome
NI
NMH
NMH
BMHD
BMHD
BMHD BMHD
YGEN
BMHD
Dr. I. Huitinga, Amsterdam, The Netherlands
as part of Brain Network Europe
ND
Evaluating molecules on tissue
ONO company Japan, Japan, Japan
ONO group (via IXA)
ND
Making blocks and staining tissue slices for industry Research on tissue on alfa-synucleinopathies for Roche
J&J prevention center (Dr Weverling), Leiden, The Netherlans
Several projects
ND
B
DNA sequencing / functional tests/ Metabolite measurements
Salomons, G.S.
B
DNA sequencing of patient cohorts
Salomons, G.S. (Janssen, E.)
B
Metabolite measurements
Roche, Basel, Basel, Switserland
ND
World wide collaborators/customers
BMHD
S. Mahmutoglu, Dept of Clinical and Metabolic Genetics/Pediatrics Sickkids, Toronto, Australia M. Gibson, Dept of Experimental and Systems Pharmacology (ESP), WSU College of Pharmacy, Spokane WA, USA
106
BMHD
BMHD
Annual Report 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Salomons, G.S. (Brink, H. ten)
Short description of the used product
External collaborator (research unit or societal group)
D
Providing stable isotope labeled compounds/ analytical standards
World wide collaborators/customers
Salomons, G.S. (Struys, E.A.)
B
Use of analytical technology
Salomons, G.S. (Struys, E.A.)
B
Use of analytical technology
Salomons, G.S. (Struys, E.A.)
B
Use of analytical technology
Salomons, G.S. (Struys, E.A.)
B
Use of analytical technology
Schenk, G. (Geurts, J.J., Klaver, R.)
A
Schmaal, L.
A
Schmaal, L.
A
Schmaal, L.
A
Schmaal, L.
A
Schmaal, L.
A
Schmaal, L.
A
Schmaal, L., Penninx, B.W.J.H., Veltman, D.J.
A
Schmaal, L., Veltman, D.J., Penninx, B.W.J.H. Smit, J.H., Grootheest, G. van Teunissen, C.E. (Killestein, J.) Teunissen, C.E. (Scheltens, Ph., Visser)
Sharing of datasets and in house generated software Cooperation Hersenstichting fellowship Measuring the effects of pharmacological compounds on GABA and glutamate levels in substance dependent individuals using Jdifference spectroscopy Research on structural and functional connectivity of the brain in developing mood disorders in adolescents using graph analysis. Shared research: cosupervising PhD student on projects on neuroimaing in addiction Shared research: developing analysis protocols Using expertise in multivariate recognition analysis ("Machine lerarning") Shared research: Cosupervising PhD students from University of Antwerp on topics related to NESDA
Name of the consortium / research network
Program
BMHD
H. Hartmann, Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Germany M. Heuser, Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany D. Wisemann, Cancer Research UK, Manchester, UK Molenaar, MSc & C.J.F. van Noorden, Department of Cell Biology & Histology, Academic Medical Center Amsterdam, The Netherlands
BMHD
BMHD
BMHD
BMHD
University of Calgary, Calgary, Canada, AB
NI
The PsycoLaus study (Dr. Martin Preisig), The Netherlands
NMH
Vanderbilt University, Institute of Imaging Science (Dr. Kevin Waddell), Nashville, USA
NMH
Monash Biomedical Imaging (MBI), Monash University (Prof. Murat Yucel, Dr. Alex Fornito, Prof. Nick Allen, Dr. Sarah Whittle), Melbourne, Australia
NMH
Academic Medical Center, Amsterdam, The Netherlands
NMH
University of Southern California, Marina del Rey, USA
NMH
Donders Institute (dr. A. Marquand), Nijmegen, The Netherlands
NMH
University of Antwerp, Antwerp, Belgium
NMH
A
Research network: Enhancing Neuro Imaging Genetics Through Meta-analysis
ENIGMA: Enhancing Neuro Imaging Genetics Through Metaanalysis: MDD working group (collaboration between 18 research institutes worldwide)
ENIGMA Major Depressive disorder (MDD) working group
NMH
A
Research network
6 partners in the Netherlands
BIOLINK
NMH
50 centers, EU
EU
NI
EU-JPND consortium (60 centers), Karolinska Institute, Stockholm, Sweden
BIOMARKAPD
ND
B A
BioMS-eu; research network Collaborative development of protocols, share dementia patient data
107
Annual Repprt 2015 - Appendices
Investigator (between brackets other investigators involved) Teunissen, C.E. (Willemse) Teunissen, C.E. (Polman, C.H., Uitdehaag, B.M.J., Barkhof, F., Geurts, J.J.G.)
Type of collaborration*
Short description of the used product
External collaborator (research unit or societal group)
D
JPND project
EU-JPND consortium (5 centers), IBBL Luxembourg, Luxembourg
B
SUMMIT-centers; multicenter study
Kappos, Dejager, Weiner, Sawcer, Oksenberg and others., Swiss, USA
Veerhuis, R.
B
Veerhuis, R. (Struys, E.A.)
B
Veerhuis, R.
B
Joint research on Complement activation in AD
Veerhuis, R.
B
Joint research on role of clusterin in coagulation
Expert and advisor + joint biosensor research Joint research on apoE isoforms
Research network: Enhancing Neuro Imaging Genetics Through Meta-analysis Research network: Enhancing Neuro Imaging Genetics Through Meta-analysis Research network: Enhancing Neuro Imaging Genetics Through Meta-analysis Research on Panic Disorder subtypes Use of cell culture facility
Name of the consortium / research network
Program
CSF biobanking
ND
Basel, Boston, San Francisco
NI
TNO (dr. B.M. de Boer), Rijswijk, The Netherlands Univ of Naples Parthenope (Prof. G. Sorrentino), Naples, Italy Department of Infection, Immunity and Biochemistry, Cardiff University (Prof. B.P. Morgan), Cardiff, UK Erasmus MC, Hematology dept (dr. D.C. Rijken), Rotterdam, The Netherlands
TNO; Van ’t Hoff Program PhD student exchange
ND NMH ND NMH
ENIGMA: Enhancing Neuro Imaging Genetics Through Metaanalysis
ENIGMA Schizophrenia working group
NMH
ENIGMA: Enhancing Neuro Imaging Genetics Through Metaanalysis
ENIGMA Addiction working group
NMH
ENIGMA: Enhancing Neuro Imaging Genetics Through Metaanalysis
ENIGMA PTSD working group
NMH
Veltman, D.J.
A
Veltman, D.J.
A
Veltman, D.J.
A
Veltman, D.J.
A
Vies, S.M. van der
E
Vies, S.M. van der
E
Use of IHC facilities
Vies, S.M. van der
E
Use of IHC facilities
B
Use of Image Analysis facility
UMC Utrecht, Utrecht, The Netherlands
Use of Image Analysis facility Use of Image Analysis facility
Voorn, P. (Vanderschuren, prof.dr.) Voorn, P. (Booij, prof.dr.) Voorn, P. (Weerdt, L. vd)
ND NMH ND NMH
CAPRI, University of Antwerpen, Antwerpen, Belgium Merck-Sharpe & Dohme, Boston, USA Immunovo B.V., s Hertogenbosch, The Netherlands PamGene International, s Hertogenbosch, The Netherlands
NMH ND ND ND ND
A
BBB models in epilepsy
Vries, H.E. de
A
Vries, H.E. de (Dr G Kooij)
Exchange of cells and biologicals
A
Exhange of researchers
Vries, H.E. de
B
Heart Brain connection: shared post-doc
AMC, Amsterdam, The Netherlands LUMC Leiden, Leiden, The Netherlands Dr E van Vliet (UvA), Amsterdam, The Netherlands Prof.dr. J Hendriks, Hasselt, Belgium Prof.dr.B Engelhardt, Bern, Switserland prof.dr. M Daemen (AMC), Amsterdam, The Netherlands
Vries, H.E. de (Drs. C Derada Troletti)
B
Host lab for secondments
Prof.dr. M. Schwaninger, Lubeck, Germany
NI
Vries, H.E. de (Drs. C Derada Troletti)
ITN nEUROinflamm ation network
D
Dr. IA Romero, London, UK
BtRAIN
NI
Vries, H.E. de
D
Vries, H.E. de
Vries, H.E. de, Horssen, J. van Vries, H.E. de, Horssen, J. van Vries, T.J. de (Pattij, T; Carr, M; Struik, R; van der Roest, M.)
B B
microRNA exchange /data set / siRNA Shared PhD student (Vanmol)
D
CNS tissue & CSF samples
D
CNS tissue, biological compounds
B
Optogenetic tools
ND ND NI NI NI NI
Prof.dr. J Hendriks
NI
Dr. Huitinga, University of Amsterdam, NIN, Amsterdam, The Netherlands
NI
Prof. N. Hellings, Hasselt, Belgium University of Sussex , Sussex, UK
108
Biomed Institute
NI NMH
Annual Report 2015 - Appendices
Investigator (between brackets other investigators involved)
Type of collaborration*
Short description of the used product
Wilhelmus, M.M.M.
A
Sharing data sets
Wilhelmus, M.M.M. (Ed van Bavel)
A
Sharing data sets
Wilhelmus, M.M.M.
A
Sharing data sets
Wilhelmus, M.M.M.
A
Sharing data sets
Wilhelmus, M.M.M.
A
Sharing data sets
Wilhelmus, M.M.M.
A
Sharing data sets
Wolf, N.I.
A
Sharing of dataset within research collaboration
Wolf, N.I. (Knaap, M.S. van der)
A
Sharing of dataset within the consortium
Wolf, N.I.
A
Sharing of dataset within the consortium
External collaborator (research unit or societal group) Mathias Jucker, Tubingen, Germany Erik Bakker, Amsterdam, The Netherlands William Van Nostrand, New York, USA Vittorio Gentile, Napels, Italy Zedira GmbH, Darmstad, Germany Louise v/d Weerd, Leiden, The Netherlands dr. Hobson, Wilmington DE, USA, Wilmington DE, USA dr. Cas Simons, Dept. of Genetics, Queensland University, , St Lucia, Australia dr. Gröschel, Tübingen, Germany, Tübingen, Germany
Name of the consortium / research network
Program ND ND ND ND ND ND BMHD BMHD BMHD
b. Research products for peers and societal target groups and outreach activities Abbreviatons: BIT: Brain Imaging Technology; BMHD: Brain Mechanisms in Health & Disease; ND: Neurodegeneration; NI: Neuroinflammation; NMH: Neurobiology of Mental Health
Contributions to a directive, protocol or policy note (e.g. reports, guidelines) Author(s)/name researcher(s) Boellaard, R. + 25 others Boellaard, R., Graham MM, Wahl RL, Hoffman JM, Yap JT, Sunderland JJ, Perlman ES, Kinahan PE, Christian PE, Hoekstra OS, Dorfman GS. Rozemuller, A.J.M. et al. UMCUtrecht
Title/topic Guideline of multicenter PET/CT quantification/standardisation
Committee
Program
EANM Physics committee
BIT
Protocol on PET/CT quantification/standardisation
UPICT (RSNA)
BIT
Priondiseases in the Netherlands
RIVM infectious diseases
ND
Research outputs other than publications (instruments, infrastructure, datasets, software tools or designs) *Type of output: A: Software tools, designs or websites; B; Consultancy; C: Datasets; D: Clinical trial guidance; E: Infrastructure; F: Instruments; G: Other research product (post publication evaluations) Investigator
Type of output*
Name of product
Short desripton
Barkhof, F.
A
PML
E-learning website about PML; https://ms-pml.org
Beek, J.H.G.M. van
A
FluxEs
Berendse, H.W.
C
VUmc Parkinson cohort
Berg, W.D.J. van de
B
Prioritizing and classification of antibodies
Open source computer package: Software to analyze metabolic fluxes Clinically phenotyped Parkinson patients affinity and specificity of antibodies for alpha-syn were analyzed.
109
Intended target of the product
Metabolic physiologists, bioinformaticians
Program BIT ND NI ND
Scientific peers
ND
Industry
ND
Annual Repprt 2015 - Appendices
Type of output*
Name of product
A
www.nabca.eu
Berg, W.D.J. van de
E
Normal Aging Brain Collection (NABC)
Boellaard, R.
A
ACCURATE
A
SUCROSE
A
Intended target of the product
Program
Academic society
ND
Academic society and industry
ND
Scientific researchers
BIT
estimates vesicle fusion rates
Synapse researchers
BMHD
www.tweelingenregister.org
comprehensive website on NTR research and output
Fellow scientists & participants
NMH
G
Twinfo
annual newsletter of the NTR (over 60,000 printed)
Participants & other interested parties
NMH
A
http://www.facebook.com/ NederlandsTweelingenRegis ter/
Facebook page NTR
Participants & other interested parties
NMH
A
http://twitter.com/NTR_VU/
Twitter feed about the social side of the NTR
Participants & other interested parties
NMH
A
https://twitter.com/NTRscie nce
Twitter feed about the scientific output of the NTR
Fellow scientists
NMH
Foncke, E.F.
C
VUmc Parkinson cohort
Scientific peers
ND
Geurts, J.J.G.
B
Consultancy for Novartis
Neurologists
NI
Geurts, J.J.G.
B
Consultancy for Genzyme
Education, experts
NI
Scientific Peers, Health Care professionals and patients
BMHD
Investigator Berg, W.D.J. van de
Cornelisse, L.N. Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology
Heine, V.M.
A
www.ipscenter.nl
Heuvel, O.A. van den
A
www.vumc.nl/cnp
Hulst, H.E.
B
Consultancy for Genzyme
Koellinger, P.D.
E
Social Science Genetic Association Consortium
Koellinger, P.D.
A
www.thessgac.org
LinkenkaerHansen, K.
A
Neurophysiological Biomarker Toolbox
LinkenkaerHansen, K.
B (valoriz ation)
Foundation of NBT Analytics BV
Meredith, R.M.
A
www.neurodevdisorders.org
Munck, J.C. de
A
http://www.demunck.info/s oftware/index.html
Penninx, B.W.J.H.
A
www.nesda.nl
Peterman, E.J.G.
A
KymographClear
Short desripton website of Normal Aging Brain Collection Amsterdam Collection of postmortem MRI and brain tissue of aged individuals Tool for quantitative analysis of PET/CT studies
Clinically phenotyped Parkinson patients grey matter pathology and cognition MS grey matter pathology and cognition MS The iPS center connects state-of-the art scientific technologies to serve basic and translational research with the goal to improve current and to develop new treatment options for a variety of brain disorders. Information about the Center Neuropsychiatry Parkinson grey matter pathology and cognition MS Organization and steering of one of the largest genetic research consortia Information about the consortium and repository of research results open-source Matlab package and wiki for M/EEG biomarker analysis
NMH Education, experts
NI
Scientific Peers
NMH
Scientific Peers and general public
NMH
Scientists and clinicians
BMHD
Scientific researchers
BMHD
Scientific peers & patients
BMHD
Scientific peers
BIT
Information about the NESDA study
General public, participants of study, NESDA researchers
NMH
Kymograph plugin for ImageJ
Scientific Peers
BIT
Data analytics company; EEG analysis for clinical trials Website for first Dutch developmental disorders meeting (2016) and to be developed with information and links to Dutch organisations and research institutes in this field. software tools for brain image analysis
110
Annual Report 2015 - Appendices
Investigator Peterman, E.J.G. Petzold, A. Polderman, T.J.C. Posthuma, D.
Type of output*
Name of product
A
KymographClear
D
Quality control (https://oscar-ib.org)
Short desripton Stand-alone kymograph analysis software Training and certification for ocular imaging as required for studies using this method as secondary outcome Managing content of BG website gene set analyses
Intended target of the product
Program
Scientific Peers
BIT
Neurologists, ophthalmologists, retinal imaging specialist/technician Scientific peers, BG members Scientific peers
A
Behavior Genetics (BG) website JAG
Posthuma, D.
A
MAGMA
Posthuma, D.
A
TATES
Posthuma, D.
A
JAMP
advanced gene set analyses summary statistics multivariate GWAS flexible multivariate GWAS
Posthuma, D.
A
IPS expertise center
website: ipscenter.nl
Posthuma, D.
E
Genetic Cluster Computer
Posthuma, D.
C
BinnensteBuiten
Posthuma, D.
C
NESCOG
Ros, B.
A
Cov3KP (http://www.math.vu.nl/~de gunst/flip_flop_flop.m)
Salomons, G.S.
A
Public database of DNA variants in specific genes
Salomons, G.S.
B
Expertise in Creatine deficiency syndromes/ D-2hydroxyglutaric aciduria
Schenk, G.
B
Microscopy workshop
Teunissen, C.E.
B
Teunissen, C.E.
B
Vries, T.J. de
B
Tri-tetrode microdrive with optic fibre
Wattjes, M.P.
A
E-learning
Wattjes, M.P. Wiel, M.A. van der Wiel, M.A. van der Wiel, M.A. van der
B
MS Imaging curriculum
A
ShrinkNet
A
GRridge
R package for classification
Peers
A
GlobalSeq
Peers
B
Key opinion leader for PA consulting Group, Life Sciences and Healthcare, London, United Kingdom.
R package for associating SNPs with RNAseq data Consultancy on Biomarkers in Alzheimer’s disease
Industry
Wilhelmus, M.M.M.
A
Member of the Scientific Advisory Board of journal: Medidact Neurologie Commentary on Biomarkers for Neurocompass.education
Supercomputing power and storage space Clinical mental disorder cohort - children general population cohort Algorithm for estimating the covariance matrix of a matrix variate normal model where the covariance matrix is a Kronecker product of three components Dataset (variants in genes associated with certain neurometabolic disorders: www.LOVD.nl/‌ including www.LOVD.nl/SLC6A8; and 6 other genes (D2HGDH, L2HGDH, ASPA, GATM, GAMT, SSADH); curator G.Salomons) obtained from our laboratory and from literature Consultancy in the field of inborn errors of neurometabolism Microscopy workshop on the histopathology of multiple sclerosis Advise on contents of educational website and journal for neurologists Advise on contents of educational website for neurologists Snimal tool for simultaneous recording and optogenetic manipulation of neurons in vivo E-Leaning on PML in MS patients Educational platform R package for estimating molecular networks
111
NI NMH BMHD
Scientific peers
BMHD
Scientific peers
BMHD
Scientific peers Scientific peers, medical professionals, patients
BMHD
Scientific peers
BMHD
Scientific peers
BMHD
Scientific peers
BMHD
NeuroImage readers interested in EEG/MEG covariance modeling
BIT
Scientific peers
BMHD
Scientific peers/ Health care providers
BMHD
Pharma
NI
Neurologists and nurses
ND
Neurologists
ND
Scientific peers
NMH
https://ms-pml.org/
NI
Peers
BMHD
NI BMHD NMH BMHD NMH BMHD NMH ND
Annual Repprt 2015 - Appendices
Investigator
Type of output*
Name of product
Yaqub, M.
G
Superpk
Yaqub, M.
C
pk11195 dataset
Short desripton INMIND member guiding for using superpk tool PK11195 healthy control database for INMIND
Intended target of the product
Program
INMIND consortium
BIT
INMIND consortium
BIT
Outreach activities for societal target groups Lectures for health care professionals, general public and patients (non-scientific audience) Investigator Abdellaoui, A. Abdellaoui, A. Bartels, M. Bartels, M. Bartels, M.
Topic History and Future of Genetics – Twin Studies and Beyond Genetic Variation in the Netherlands Wellbeing of the Dutch Population Determinants of Wellbeing and Happiness Explaining causes of individual differences in Wellbeing and Happiness
Bartels, M.
Geluk
Bartels, M.
Geluk en Genen
Bartels, M.
Urban Healthy Living, Happiness and the City
Bartels, M.
Happiness is not normal
Berendse, H.W.
Behandeling van niet-motorische stoornissen bij de ziekte van Parkinson
Berendse, H.W.
Ziekte van Parkinson en multipele systeem atrofie
Berendse, H.W.
Chairman symposium 'Kopzorgen'
Berg, W.D.J. van de
Variatie in bouwstenen bij Alzheimer en Parkinson cellen
Berg, W.D.J. van de
Ons brein
Boomsma, D.I.
Gedragsgenetica
Boomsma, D.I.
Het laatste nieuws over twee- en meerlingonderzoek
Boomsma, D.I.
Van Gen naar Gedrag
Boomsma, D.I.
Breakthroughs in twin research
Boomsma, D.I.
Twins and “Omics”
Boomsma, D.I.
Aggression: Where do we stand?
Audience Wageningen, Studium Generale Wageningen UR
Date
Program
15-9-2015
NMH
Delft, OTB-Colloquium TU Delft
10-11-2015
NMH
8-1-2015
NMH
21-1-2015
NMH
30-1-2015
NMH
26-3-2015
NMH
9-9-2015
NMH
17-11-2015
NMH
10-11-2015
NMH
12-3-2015 10-12-2015
ND
25-9-2015
ND
11-4-2015
ND
11-6-2015
ND
6-3-2015
ND
13-1-2015
NMH
18-1-2015
NMH
15-4-2015
NMH
1-6-2015
NMH
22-9-2015
NMH
22-10-2015
NMH
Duiven, Invited Speaker at meeting HopeXXL Roelofarendsveen, Invited Speaker at Lionsclub Alkemade Invited Speaker at Rotary Amsterdam-West Invited speaker and discussant at Kenniscafe Almere Invited Speaker Masterclass at the ESSA-Erasmus Executive Programs Invited Speaker at Studium Generale Utrecht University Invited Lecture at the National meeting of the European Mentoring and Coaching Council (EMCC Netherlands)/Nederlandse Orde van beroepscoaches (NOBCO) Neurologists, residents in neurology Specialists in rehabilitation medicine / residents in rehabilitation medicine Parkinson patients, caregivers, health care professionals Patients and donateurs Children at primary school (7-8 years of age) Natuurkundig Genootschap Wessel Knoops in Arnhem (1824) Amsterdam, Bijeenkomst NVOM op de VU Amsterdam, Tinbergenzaal, KNAW - symposium i.h.k.v. Akademie Hoogleraarschap SRON Netherlands Institute for Space Research, Dalfsen AMC Ruysch Lezing (invited talk) Amsterdams Medisch Centrum Symposium Beyond the Genetics of Aggression; From Clinic to Research and Back; KNAW
112
Annual Report 2015 - Appendices
Investigator Boomsma, D.I.
Topic Nature or nurture: inzichten uit meerlingonderzoek
Boomsma, D.I.
De erfelijkheid van gelijkenis
Bugiani, M.
Pathology of childhood white matter disorders
Bugiani, M.
CNS infections and other inflammatory diseases
Bugiani, M.
Het belang van hersenonderzoek
Douw, L.
Twitter in je hoofd
Douw, L.
Neuronerds
Flier, W.M. van der
How clinical can you go?
Flier, W.M. van der
Alzheimer: onderzoek om niet te vergeten
Flier, W.M. van der
Onderzoek naar alzheimer: Hoe ver zijn we?
Flier, W.M. van der
ORATIE: Determinants of cognitive decline and dementia
Flier, W.M. van der
Alzheimer – waar staan we nu?
Flier, W.M. van der
De invloed van veroudering en Alzheimer op breinplasticiteit
Flier, W.M. van der
Onderzoek om niet te vergeten: de ziekte van Alzheimer.
Flier, W.M. van der
Wetenschappelijk onderzoek; wat hebben we geleerd?
Flier, W.M. van der
Determinants of cognitive decline and dementia.
Flier, W.M. van der, Scheltens, Ph. Geurts, J.J.G.
Lezing + Signeersessie ~ het Alzheimermysterie Anatomieles aan de hand van kalfsbrein
Audience Nederlandse Vereniging van Kinderartsen (NVK), Veldhoven Utrecht, Lezing Domus Dag (Geschiedenis van de Geneeskunde)
Date
Program
5-11-2015
NMH
11-12-2015
NMH
VAP congress
19-3-2015
BMHD
16-4-2015
BMHD
23-10-2015
BMHD
29-10-2015
BIT
26-9-2015
BIT
1-1-2015
ND
1-4-2015
ND
14-10-2015
ND
23-9-2015
ND
30-10-2015
ND
10-11-2015
ND
14-11-2015
ND
24-11-2015
ND
7-12-2015
ND
Lay audience, Scheltema
24-9-2015
ND
bezoekers Crowdfest
26-9-2015
NI
12-9-2015
NMH
22-9-2015
NMH
23-10-2015
BMHD
11-4-2015
NMH
Nederlandse vereneging voor Neurologie -cursus neuropathologie 15 years Center for childhood white matter disorders VWO students, context "Anatomische Les" Crowdfest visitors Symposium Non-academic career opportunities, Neuroscience Master, NCA, Amsterdam (MSc/PhD students) Lezingencyclus VU vereniging, Almelo (lay audience) Workshop bij Jaarevent Deltaplan Dementie. Amersfoort (dementia professionals) family, friends, colleagues (lay audience) Congres Alzheimer, Ede (dementia professionals) HOVO Brein in Beeld, Amsterdam (lay audience) De Vereniging ‘Het Nederlandsch Natuur- en Geneeskundig Congres’, Leiden (lay audience) Congres Moderne Dementiezorg, Ede (dementia professionals) Voordracht bij het diner Nieuwe Hoogleraren VU, Amsterdam (VU CvB, decanen, nieuwe hoogleraren)
Geus, E.J.C. de
Genetics of Physical Activity
Geus, E.J.C. de
Genetics of Exercise behaviour and Exercise Ability
Heine, V.M.
Stamceltherapie van wittestofziekten, waar zijn we?
Heuvel, O.A. van den
BEWARE- behandeling van wearingoff gerelateerde angst
Pediatric Work Physiology XXiX edition, UMC Utrecht Julius Academy Wageningen, Studium Generale, Wageningen Universiteit 15yr CCWMD: Symposium voor patiënten, families en andere betrokkenen Wereld Parkinsondag (patients) Nieuwegein
Holstege, H.
100-plus onderzoek
Laego Huisartsen congres
29-01-2015
Gastcollege middelbare school
13-02-2015
bezoekers Crowdfest
26-9-2015
NI
ELA, patients and families, Paris, France
29-3-2015
BMHD
ULF, patients and families, Omaha, USA
15-7-2015
BMHD
Families and patients, Amsterdam
23-10-2015
BMHD
Holstege, H. Hulst, H.E. Knaap, M.S. van der Knaap, M.S. van der Knaap, M.S. van der
Genetics of dementia and 100-plus Study Anatomieles aan de hand van kalfsbrein Update on undetermined leukodystrophies Unclassified Leukodystrophies: What we have achieved in the last 20 years Wat in 15 jaar bereikt is en wat de toekomst gaat brengen
113
BMHD ND BMHD ND
Annual Repprt 2015 - Appendices
Investigator
Topic
Audience
Date
Program
Kock, C.P.J. de
Our brain: we are in control!
Charity service club (Lions)
16-9-2015
Mansvelder, H.D.
Roken, drinken en puberhersenen (Discovery night)
General public
16-9-2015
Mansvelder, H.D.
Profs op het podium
General public
11-10-2015
Middeldorp, C.M.
Psychopathologie in gezinnen. Wie lijken er op elkaar en waarom?
Penninx, B.W.J.M.
Kort praatje over nieuwe onderzoekslijnen depressie in Nederland
Nijmegen, Academisch uurtje Karakter Depressievereniging themamiddag “Prioriteiten in onderzoek naar depressie” (patients)
BMHD BIT ND NMH BIT ND NMH
Schoonheim, M.
Een frisse blik op biologische processen door fluorescentie aan individuele moleculen Lecture 'Genetics of the brain and cognition' Lezing Vriendenloterij kick off Preventie van Alzheimer: feit en fictie The key role of imaging in multiple sclerosis What's up in.. MS en cognitie
Schoonheim, M.
MRI bij MS
Peterman, E.J.G. Polderman, T.J.C. Scheltens, Ph. Scheltens, Ph. Schoonheim, M.
Wattjes, M.P.
Innovaties voor kwetsbare Amsterdammers met GGZ problematiek Professoren op het podium in Purmerend Lezing Natuurkundig Gezelschap Middelburg De rol van SPPL2b bij pathogenese van de ziekte van Alzheimer. Oegstgeest. Bloed biomarkers: hoop of klinische realiteit? Dementie update. Amsterdam. Witte stof banen
Weering, J.R.T. van
Neuroscience
Smit, J.H. Spijker, S. Spijker, S. Teunissen, C.E. Teunissen, C.E.
Werf, Y.D. van der Werf, Y.D. van der
Nemo weekend van de wetenschap: Wat gebeurt er in je hoofd als je leest Hack the Brain Festival: Brain slicing event with Arnon Grunberg and Joel Broekaert
Koninklijke Maatschappij voor Natuurkunde "Diligentia" Higher education of elderly (HOVO) Nova Media werknemers lay audience Neurologists / radiologists (international) (Para)medici (Nederland) Pharmaceutical employees (international, Genzyme) Health-professionals, Inurance companies, board members of hospitals: SIGRa
1-6-2015
NMH
27-11-2015
NMH
19-10-2015
BIT
12-1-2015
NMH
29-10-2015
ND
5-6-2015
ND
5-6-2015
NI
1-12-2015
NI
14-9-2015
NI
8-12-2015
NMH BMHD NMH BMHD NMH
General public
16-3-2015
General public
25-9-2015
Donateursmeeting ISAO
11-6-2015
ND
Professionals in dementia care
30-3-2015
ND
AIOS Neurologie NL Academische week 2015; Johannes Fontanes College Secondary School
19-11-2015
NI
11-5-2015
BMHD
Children
4-10-2015
PhD students, students, lay people
5-6-2015
BIT ND NMH BIT ND NMH BIT ND NMH BIT ND NMH BIT ND NMH
Werf, Y.D. van der
Hersenstichting dag 'Flexibele hersenen'
Patients and their relatives
15-10-2015
Werf, Y.D. van der
Public lecture museum Twentse Welle, Enschede, Netherlands
Lay audience
28-6-2015
Werf, Y.D. van der
Public lecture Film by the Sea festival Vlissingen
Lay audience
12-9-2015
Lay audience
10-10-2015
BIT ND NMH
Families and patients
23-10-2015
BMHD
Families and patients
7-10-2015
BMHD
Families and patients Radiologist, Neurologist, MHH, Hannover Germany
28-3-2015
BMHD
17-12-2015
NI
Wolf, N.I.
Brain slicing event with Arnon Grunberg at the festival ‘Land van de Nieuwsgierigheid’ Leuven, Belgium HSCT for Metachromatic Leukodystrophy Hypomyelination
Wolf, N.I.
Unsolved cases in hypomyelination
Wolf, N.I.
MRI in MS
Werf, Y.D. van der Wolf, N.I.
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Annual Report 2015 - Appendices
Contributions, based on research, to post initial education Investigator
Topic Computational modelling of metabolism in health and disease
Audience
Date
Program
AMC graduate school
3-12-2015
ND
Human Neuroanatomy
AIOS Neurology
Berg, W.D.J. van de
Human Neuroanatomy
POAG: Radiologist, neurologist etc
Horssen, J. van
Masterclass MS pathologie
neurologen nascholing
Horssen, J. van
ONWAR
PhD students (neuroscience)
Beek, J.H.G.M. van Berg, W.D.J. van de
19 to 20-112015 15 to 16-122015 January & April 2015
ND ND NI NI
Koellinger, P.D.
Genoeconomics
PhD students and researchers
Pattij, T.
Klokhuis vragendag 2015 Stress-gerelateerde aandoeningen en lichamelijke gezondheid
Children
2-4-2015 till 164-2015 7-6-2015
WASH-cursus Terschelling
10-11-2015
NMH
10-11-2015
NMH
AprilSeptember 2015 (6 sessions)
ND
9-9-2015
NI
Penninx, B.W.J.H.
NMH NMH
Penninx, B.W.J.H.
Wat leren we van genetica en depressie, NESDA studie
WAGEN-cursus Terschelling What About Genes Environment and Neurotransmission
Pijnenburg, Y.A.L.
Apsycho-educative interventon
caregivers of patients with a frontal type dementia
Schoonheim, M.
Cognitie bij MS
Neurologen in opleiding (Nederland)
Werf, Y.D. van der
VUMC academy (formerly PAOG)
Neuroradiologists
15 to 16-122015
Werf, Y.D. van der
Course 'Functional Neuroanatomy'
PhD students Neuroscience
20 to 24-2015
Wilhelmus, M.M.M.
Lecturer and coordinator of the 'Neurodegenerative disorders' day during the post-graduate Onwar course on Neuropsychopharmacology
post-graduates
9-9-2015
ND
URL
Date
Program
1-1-2015
ND
5-3-2015
NMH
9-3-2015
NMH
28-3-2015
NMH
7-4-2015
NMH
25-4-2015
NMH
29-7-2015
NMH
3-10-2015
NMH
10-10-2015
NMH
BIT ND NMH BIT ND NMH
Media attention Investigator Berendse, H.W. Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology
Medium: Name source; Topic Magazine (online/print): Parkinson Magazine; Netherlands Parkinson Cohort Television: RTL4; RTL Late Night met Humberto Tan over SBS6 programma de nationale tweelingtest 2015 Television: SBS6; De Nationale Tweelingtest 2015 - meerdere afleveringen Newspaper (print): Volkskrant; Zij hebben het ook niet makkelijk?!? Newspaper (print): Parool; Geluksgevoel 35 procent genetisch Newspaper (print): Telegraaf; Treetje terug op de geluksladder Radio: RTVNH; Interview over nieuw tweelingonderzoek Newspaper (print): Volkskrant; Wat ons IQ werkelijk over ons zegt Magazine (online/print): Vrij Nederland; Het idee: ‘Depressie is iets anders dan gebrek aan geluk’
http://www.sbs6.nl/programm as/de-nationale-tweelingtest2015/
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Annual Repprt 2015 - Appendices
Investigator Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Dept. Biological Psychology Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der
Flier, W.M. van der
Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der Flier, W.M. van der, Scheltens, Ph. Flier, W.M. van der, Scheltens, Ph.
Medium: Name source; Topic Other online sources (weblog, newsfeed, newsletter): Universiteit van Nederland; De Universiteit van Nederland over Geluk Radio: De Kennis van Nu - Radio 5; De Kennis van Nu Radio - over de erfelijkheid van depressie Other online sources (weblog, newsfeed, newsletter): NewScientist; Een beetje gekte is goed voor de creativiteit Newspaper (print): Parool; Gelukkig worden? Tel je zegeningen Newspaper (print): Volkskrant; commentaar bij artikel over depressie en dementie Radio: Tros Nieuwsshow; alzheimer Magazine (online/print): VOZ magazine ; alzheimer center/ life researcher Newspaper (print): Parool (+doorgezet naar provinciale kranten); release Het alzheimermysterie Radio: HoezoRadio dubbelinterview; release Het alzheimermysterie Radio: Tros Nieuwsshow ; release Het alzheimermysterie Magazine (online/print): Margriet online ; Alzheimer Television: RTL late night ; release Het alzheimermysterie Newspaper (print): Volkskrant dubbelinterview; release Het alzheimermysterie
Geurts, J.J.G.
Newspaper (print): Vrij Nederland; Interview
Geurts, J.J.G.
Radio: Radio 5; Nagesprek FAMElab
Geurts, J.J.G.
Television: De Kennis van Nu; Jury member FAMElab
Geurts, J.J.G.
Radio: Radio 1; Promotie boek 'Het zingende paard'
Heine, V.M.
Heuvel, O.A. van den
Heuvel, O.A. van den
Magazine (online/print): vumc instantmagazine; Het VUmc Centrum voor Kinderen met Wittestofziekten bestaat dit jaar 15 jaar en doet wetenschappelijk onderzoek met als doel deze hersenziekten in de toekomst te kunnen genezen. Op 22 en 23 oktober 2015 is er een wetenschappelijk symposium ter gelegenheid van dit jubileum. Magazine (online/print): Emagazine VUmc in Praktijk ; Lichtgebrek en Depressie Other online sources (weblog, newsfeed, newsletter): ‘Een lichtpuntje in de duisternis op blue Monday’
URL
Date
Program
https://www.youtube.com/wa tch?v=W_t5oFz5plk&feature=y outu.be
4-11-2015
NMH
6-11-2015
NMH
20-11-2015
NMH
28-11-2015
NMH
1-3-2015
ND
1-3-2015
ND
1-5-2015
ND
23-9-2015
ND
25-9-2015
ND
19-9-2015
ND
1-10-2015
ND
21-9-2015
ND
19-9-2015
ND
16-1-2015
NI
22-4-2015
NI
22-4-2015
NI
16-9-2015
NI
http://vumc.instantmagazine.c om/de-specialist/september2015#!/close-up
1-9-2015
BMHD
http://vumc.instantmagazine.c om/vumc-in-praktijk/7
January 2015
NMH
http://www.debeterewereld.nl /
19-1-2015
NMH
http://www.newscientist.nl/ni euws/een-beetje-gekte-isgoed-voor-de-creativiteit/
https://www.vn.nl/goedeneurowetenschappers-zijninterdisciplinair/ http://www.npowetenschap.nl /programmas/de-kennis-vannu-tv/extra/live.html http://www.npo.nl/de-kennisvan-nu/22-042015/VPWON_1236029 http://www.radio1.nl/item/31 6159Wat%20is%20excellentie?.html
116
Annual Report 2015 - Appendices
Investigator Heuvel, O.A. van den
Heuvel, O.A. van den
Medium: Name source; Topic Other online sources (weblog, newsfeed, newsletter): Parkinson TV; Verslaving en Parkinson (Parkinson TV) Magazine (online/print): Parkinson Magazine; “Ask our Psychiatrist” (Vraag het onze Psychiater)
Heuvel, O.A. van den
website: nu.nl; PhD defense Chris Vriend
Heuvel, O.A. van den
newspaper, website: telegraaf; PhD defense Chris Vriend
Heuvel, O.A. van den
website: parelsnoer.org; PhD defense Chris Vriend
Heuvel, O.A. van den
Web: De Betere Wereld; Depressie en lichttherapie
Holstege, H.
Holstege, H.
Other online sources (weblog, newsfeed, newsletter): New Scientist; Four genes discovered that will help you live beyond 100 Magazine (online/print): Paris Match; Paris Match: Vieillissement ils arrêtent la course du temps.
Holstege, H.
Newspaper (print): Noord Hollands Dagblad; Op naar volgende 100 jaar
Holstege, H.
Magazine (online/print): zorgwelzijn.nl; 100-plus en nog altijd helder en gezond
Holstege, H. Holstege, H.
Newspaper (print): Trouw; Superoud en helder van geest, hoe kan dat? Newspaper (print): Volkskrant; Annie (101) - Hoe honderdplussers oud worden
Holstege, H.
Television: De Kennis van NU; Cocumentaire 100-plus Onderzoek
Holstege, H.
Newspaper (print): Dagblad van het Noorden; Egbertje Leutscher voorop bij het 100-plusonderzoek
Holstege, H.
Magazine (online/print): Ad Valvas; Over het 100-plus onderzoek
Holstege, H. Holstege, H. Holstege, H.
Magazine (online/print): Branchebelang Thuiszorg; Over het 100-plus onderzoek Magazine (online/print): 50pluswereld; Waarom is uw moeder/vader dement of juist niet Magazine (online/print): Arts & Auto: ; Niet demente honderdplussers gezocht,
Holstege, H.
Television: NOS Journaal; Heldere 100+'ers onderzocht
Holstege, H.
Television: Nieuwsuur; Dementie: ongrijpbaar en onbegrepen
URL
Date
Program
http://www.parkinsontv.nl/uit zending-18-4-december2015/gemistdetail
4-12-2015
NMH
2015: 5 issues
NMH
28-4-2015
NMH
29-4-2015
NMH
28-4-2015
NMH
19-1-2015
NMH
17-12-2015
BMHD ND
29-01-2015
BMHD ND
2-10-2015
BMHD ND
14-7-2015
BMHD ND
3-11-2015
BMHD ND
10-6-2015
BMHD ND
28-10-2015
BMHD ND
30-10-2015
BMHD ND
14-10-2015
BMHD ND
21-07-2015
BMHD ND
20-07-2015
BMHD ND
14-07-2015
BMHD ND
10-2-2015
BMHD ND
13-09-2015
BMHD ND
https://www.parkinsonvereniging.nl/actueel/parkinso n-magazine/ http://www.nu.nl/gezondheid/ 4039502/parkinsonpatientendepressieverdopaminegebrek.html http://www.telegraaf.nl/gezon dheid/23983089/__Dopamineg ebrek_maakt_parkinsonpatient _depressief__.html http://www.parelsnoer.org/pa ge/De-Parels/Parkinson http://www.debeterewereld.nl /lichaam-geest/eenlichtpuntje-de-duisternis-opblue-monday/ https://www.newscientist.com /article/dn28688-four-genesdiscovered-that-will-help-youlive-beyond-100/ http://www.alzheimercentrum .nl/uploads/100plus/20150129 _Paris%20Match.pdf http://www.alzheimercentrum .nl/uploads/100plus/20150210 _Noord%20Hollands%20Dagbl ad.pdf http://www.zorgwelzijn.nl/Ou derenzorg/Nieuws/2015/7/100 -plus-en-nog-altijd-helder-engezond-2657105W/ http://www.alzheimercentrum .nl/uploads/100plus/20151003 _Trouw.JPG http://www.alzheimercentrum .nl/uploads/100plus/20151006 _Volkskrant.pdf http://www.npo.nl/de-kennisvan-nu/28-102015/VPWON_1241897 http://www.alzheimercentrum .nl/uploads/100plus/20151030 _Dagblad%20van%20het%20N oorden.pdf http://www.alzheimercentrum .nl/uploads/100plus/20151014 _AdValvas.pdf http://www.branchebelangthuiszorg.nl/nieuws/het-100plus-onderzoek/ http://www.50pluswereld.nl/w aarom-uw-moedervaderdement-juist-niet/ http://www.artsenauto.nl/niet -demente-100-plussersgezocht/ http://nos.nl/artikel/2060941heldere-100-ersonderzocht.html http://nos.nl/nieuwsuur/artike l/2057465-dementieongrijpbaar-enonbegrepen.html
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Annual Repprt 2015 - Appendices
Investigator Holstege, H.
Medium: Name source; Topic Radio: Radio 2 GrandCafŽ Kranenbarg; Niet_bewezen_dat_geheugenspell etjes_helpen_om_je_hersens_te_t rainen_.mp3
Holstege, H.
Radio: Radio Interview 100-plus dag; heldere 100+'ers onderzocht
Holstege, H.
Radio: RTV Drenthe; Sporen van dementie, maar er totaal geen last van: Drentse had opmerkelijke hersenen
Holstege, H. Hulst, H.E.
Koellinger, P.D.
Pattij, T.
Penninx, B.W.J.H.
Penninx, B.W.J.H.
Television: Omroeop Max; 100plus Newspaper (print): EOS Psyche en Brein; Being a neuroscientist
Magazine (online/print): EUREKA; Genoeconomics
Radio: NPO Radio 1, BNN Start; Interview on the effects of modafinil Magazine (online/print): PLUS magazine; “Good news on depression” (Goed nieuws over depressie: sneller ontdekken wat echt helpt) Newspaper (print): Het Parool; The list: Penninx named as one of 45 most influential scientists wordlwide (Het lijstje)
Peterman, E.J.G.
Radio: BNR; Van startup naar smartup
Pijnenburg, Y.A.L.
Television: geef om je hersenen; Early-onset dementia
Pijnenburg, Y.A.L. Pijnenburg, Y.A.L. Pijnenburg, Y.A.L.
Polderman, T.J.C.
Polderman, T.J.C.
Polderman, T.J.C.
Radio: NPO Radio 5; Early-onset dementia Magazine (online/print): Margriet; Early-onset dementia Newspaper (print): regionale bladen; Early-onset dementia Newspaper (print): Volkskrant, Het Laatste Nieuws, De Morgen, Neue Zuricher Zeitung, The Telegraph, & more; Publication '50 years of twin studies' in Nature Genetics Newspaper (online): Huffington Post, New York Times, World News, Latin Post, and many more; Publication '50 years of twin studies' in Nature Genetics Radio: Nieuws BV, Kennis van Nu/Radio 5, Nieuwe Feiten/Radio 1 Belgie, SotryFM Belgie; Publication '50 years of twin studies' in Nature Genetics
URL http://radio2/audiofragments/ 11/10618_Niet_bewezen_dat_geheugen spelletjes_helpen_om_je_hers ens_te_trainen_.mp3 http://nos.nl/artikel/2060941heldere-100-ersonderzocht.html http://www.rtvdrenthe.nl/nieu ws/101481/Sporen-vandementie-maar-er-totaal-geenlast-van-Drentse-hadopmerkelijke-hersenen http://tvblik.nl/tijd-voormax/afstandsmoeders http://www.uva.nl/over-deuva/organisatie/faculteiten/fac ulteiten/faculteiten/content/fo lder/faculteit-economie-enbedrijfskunde/actueel/nieuwsfaculteit-economie-enbedrijfskunde/nieuwsfaculteit-economie-enbedrijfskunde/content4/folder/2015/01/genoecono mics.html http://www.radio1.nl/item/31 3139-Smart-drug-test:Modafinil.html
http://www.bnr.nl/radio/bnrstartup/438584-1510/27oktober-van-startup-naarsmartup http://www.omroepmax.nl/ge efomjehersenen/uitzending/tv /geef-om-je-hersenenwoensdag-15-april-2015/
Date
Program
11-4-2015
BMHD ND
10-2-2015
BMHD ND
29-10-2015
BMHD ND
11-9-2015
BMHD ND
1-12-2015
NI
January 2015
NMH
6-9-2015
NMH
January 2015
NMH
6-11-2015
NMH
27-10-2015
BIT
15-4-2015
ND
15-4-2015
ND ND ND
118
5-1-2015
NMH
5-1-2015
NMH
5-1-2015
NMH
Annual Report 2015 - Appendices
Investigator
Medium: Name source; Topic
Polderman, T.J.C.
Other online sources (weblog, newsfeed, newsletter): Many posts/blogs etc.; Publication '50 years of twin studies' in Nature Genetics
Polderman, T.J.C.
Newspaper (print): Hypothese NWO; NESCOG data collection in Science Live, NEMO Amsterdam
Posthuma, D.
Magazine (online/print): ; Interview on Meta-analysis on all published twin studies
Posthuma, D.
Posthuma, D.
Posthuma, D.
Posthuma, D.
Posthuma, D.
Posthuma, D.
Posthuma, D.
Posthuma, D.
Posthuma, D.
Newspaper (print): Swiss national newspaper ; Interview on Metaanalysis on all published twin studies Magazine (online/print): EOS popular science magazine; Interview on Meta-analysis on all published twin studies Newspaper (print): Belgian national newspaper de Morgen ; Interview on Meta-analysis on all published twin studies Newspaper (print): Belgian national newspaper Het Nieuwsblad ; Interview on Meta-analysis on all published twin studies Newspaper (print): The Huffington post ; Interview on Meta-analysis on all published twin studies Radio: US radio station ‘Creating a Family’ (1M listeners); http://creatingafamily.org/adoptio n-category/genetics-vsenvironment-which-shapes-ourkids-the-most/; Interview on Metaanalysis on all published twin studies Newspaper (print): Dutch national newspaper de Volks-krant; Interview on Meta-analysis on all published twin studies Other online sources (weblog, newsfeed, newsletter): Scientific blog on our paper on the heritability of all traits Newspaper (print): Short interviews for > 20 international news sites (incl. US, Australia, UK, Spain, Indonesia, Belgium, Netherlands,), and discussionon > 10 blogs
Rozemuller, A.J.M.
Television: Met de Kennis van NU; 100+ studie (Holstege)
Rozemuller, A.J.M.
Other online sources (weblog, newsfeed, newsletter): Alzforum ; comment on research paper
Rozemuller, A.J.M. Scheltens, Ph. Scheltens, Ph.
Magazine (online/print): 100+krant; 100+ study interview patholoog Newspaper (print): Telegraaf; Vriendenloterij Television: KofieTijd; Vriendenloterij
URL http://www.biosciencetechnol ogy.com/articles/2015/05/dep th-look-historys-largestgenetic-twinstudy?cmpid=horizontalconten t; http://drjamesthompson.blogs pot.co.uk/2015/05/gone-withwind.html
http://www.biosciencetechnol ogy.com/articles/2015/05/dep th-look-historys-largestgenetic-twin-study
http://drjamesthompson.blogs pot.co.uk/2015/05/gone-withwind.html
http://www.npo.nl/de-kennisvan-nu/28-102015/VPWON_1241897 http://www.alzforum.org/new s/research-news/dementia-lamold-fungi-may-lurkalzheimers-brains
Date
Program
5-1-2015
NMH
4-1-2015
NMH
30/5/2015
BMHD
6-1-2015
BMHD
7-1-2015
BMHD
22-5-2015
BMHD
21-5-2015
BMHD
20-5-2015
BMHD
27-5-2015
BMHD
19-5-2015
BMHD
27-5-2015
BMHD
6-1-2015
BMHD
28-10-2015
ND
17-10-2015
ND
ND
119
10-10-2015
ND
10-11-2015
ND
Annual Repprt 2015 - Appendices
Investigator Scheltens, Ph. Scheltens, Ph.
Schmaal, L.
Schmaal, L.
Schmaal, L.
Schmaal, L.
Schmaal, L.
Schmaal, L.
Medium: Name source; Topic newspaper (print): Financieel Dagblad; Alzheimer Sokken newspaper (print): Medisch Contact; Hoop in de Geneeskunde Other online sources (weblog, newsfeed, newsletter): several online newssites; Several online news items after publication paper “Subcortical Brain Alterations in Major Depressive Disorder: findings from the ENIGMA Major Depressive Disorder Working Group” in Molecular Psychiatry Other online sources (weblog, newsfeed, newsletter): several online newssites; Several online news items after publication paper “Subcortical Brain Alterations in Major Depressive Disorder: findings from the ENIGMA Major Depressive Disorder Working Group” in Molecular Psychiatry Other online sources (weblog, newsfeed, newsletter): several online newssites; Several online news items after publication paper “Subcortical Brain Alterations in Major Depressive Disorder: findings from the ENIGMA Major Depressive Disorder Working Group” in Molecular Psychiatry Other online sources (weblog, newsfeed, newsletter): several online newssites; Several online news items after publication paper “Subcortical Brain Alterations in Major Depressive Disorder: findings from the ENIGMA Major Depressive Disorder Working Group” in Molecular Psychiatry Other online sources (weblog, newsfeed, newsletter): several online newssites; Several online news items after publication paper “Subcortical Brain Alterations in Major Depressive Disorder: findings from the ENIGMA Major Depressive Disorder Working Group” in Molecular Psychiatry Magazine (online/print): GezondNu magazine; 12 questions for researcher Lianne Schmaal about biology and depression
Schoonheim, M.
Magazine (online/print): Rondom MS; Multiple sclerose
Schoonheim, M.
Magazine (online/print): Rondom MS; Multiple sclerose
Schoonheim, M.
Teunissen, C.E.
Teunissen, C.E.
Other online sources (weblog, newsfeed, newsletter): Youtube (voor MSVN); Multiple sclerose Newspaper (online): several media: Vumc sites, international sites. Financial journals.; First Somascan site in Europe Other online sources (weblog, newsfeed, newsletter): Medidact Neurologie ; Conference summaries of ECTRIMS 2015
Date
Program
19-9-2015
ND
20-12-2015
ND
www.telegraaf.nl
Summer 2015
NMH
www.theguardian.com
Summer 2015
NMH
http://theconversation.com
Summer 2015
NMH
www.iflscience.com
Summer 2015
NMH
www.sciencedaily.com
Summer 2015
NMH
October 2015
NMH
1-11-2015
NI
1-8-2015
NI
16-6-2015
NI
18-12-2015
ND
8-9-2-15
ND
URL
http://msresearch.nl/sites/msr esearch.nl/files/Rondom%20M S%2051.pdf http://msresearch.nl/sites/msr esearch.nl/files/Rondom%20M S%2050.pdf https://www.youtube.com/wa tch?v=BcTK97inR4o
http://medidact.com/neurolog ie/Nieuws+ECTRIMS
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Annual Report 2015 - Appendices
Investigator
Medium: Name source; Topic
Vries, T.J. de
Radio: NPO radio 1 De Ochtend; Scientific highlights of the year: Nicotine addiciton
Wattjes, M.P.
Other online sources (weblog, newsfeed, newsletter): Press conference DGNR Meeting Cologne, Germany ; MRI in MS
Werf, Y.D. van der
website: nu.nl; Onderzoek naar hersenactiviteit bij lezen boek Arnon Grunberg
Wiel, M.A. van der
Magazine (online/print): VOZ magazine; Big Data veroorzaakt de komende jaren een Big Change in het ziekenhuis
Date
Program
28-12-2015
NMH
http://www.dgnr.org/media/d ocument/297/PM-NeuroradWattjes-Multiplesklerose.pdf.
16-10-2015
NI
http://www.nu.nl/boek/39982 06/lezers-worden-niet-vrolijkvan-nieuwste-boekgrunberg.html
23-2-2015
BIT ND NMH
http://www.vozmagazine.nl/C MS/show.do?ctx=145936,2169 35
1-7-2015
BMHD NMH
URL http://www.radio1.nl/item/33 7213-Wat-is-de-interessantstewetenschappelijkeontwikkeling-van-deafgelopen-tijd?_html=
121
Annual Repprt 2015 - Appendices
Appendix 6: Acquisition Abbreviatons: BIT: Brain Imaging Technology; BMHD: Brain Mechanisms in Health & Disease; ND: Neurodegeneration; NI: Neuroinflammation; NMH: Neurobiology of Mental Health
Investigator(s)
Project Titel
Spijker, S.
Dissection of prediction error and reconsolidation circuits of aversive-emotional memory Oxytocin as novel treatment for Prader Willi syndrome Processing multisensory evidence for decisionmaking: control by frontal versus sensory cortex Reframing the addictionoccupied mind by disrupting reconsolidation of alcohol memories through working memory interference The interplay between genetic profiles and environment in higher cognitive function The interplay between genetic profiles and environment in higher cognitive functioning The role of astrocytes in major depressive disorder: a combination of human in vitro and mouse models of depression ’Tissue Transglutaminase as a therapeutic target in Alzheimer’s Disease Differential responsiveness, morphology and biophysical properties of glial cells Imaging MS: PET
Toonen, R.F.G. Kock, C. de Pennartz, C. (UvA)
Vries, T.J. de Voorn, P. Pattij, T. Wiers, R. (UvA)
Koellinger, P. Posthuma, D. Polderman, T.J.C. Waldorp, L. (UvA) Posthuma, D.
Heine, V.M. Posthuma, D.
Willhelmus, M.
Dam, A.M.W. van
Windhorst, A.D. Vries, H.E. de Douw, L. Bugiani, M.
Schmaal L. van den Heuvel OA Schmaal L.Heuvel, O.A. van den Windhorst, A.D. Vugts, D.J. Lammertsma, A.A.
Grant Support (VU/VUmc part) € 260.000,00
Funding Organization
Funding type
Program
1
Running period in months 24
Amsterdam Brain & Mind Project
€ 200.000,00
Amsterdam Brain & Mind Project Amsterdam Brain & Mind Project
1
24
BMHD
1
24
BMHD
€ 240.000,00
Amsterdam Brain & Mind Project
1
24
NMH
€ 240.000,00
Amsterdam Brain & Mind Project
1
24
NMH
€ 260.000,00
Amsterdam Brain & Mind Project
1
24
BMHD
€ 260.000,00
Amsterdam Brain & Mind Project
1
24
BMHD
€ 3.750,00
ANW Innovation fond
1
12
ND
€ 4.250,00
Innovation grant ANW
1
7
NI
€ 100.000,00
NCA Proof of concept NCA Team Leader Grant NCA TL grant (IPB-TL5-KINGBugiani)
1
12
NI
1
12
BIT
1
12
BMHD
1
12
NMH
1
12
NMH
€ 125.000,00
NMH
Molecules to Behavior
€ 35.000,00
Acute reversible brainstem lesions reveal a potential for endogenous repair in vanishiing white matter Endophenotypes of brain diseases ENIGMA-OCD
€ 31.250,00
€ 50.000,00
NCA VU University NCA VU/VUMC
ENIGMA
€ 100.000,00
NCA-IPB
1
12
NMH
Imaging M1/M2 polarization in vivo
€ 100.000,00
NCA-IPB
1
24
BIT
€ 50.000,00
122
Annual Report 2015 - Appendices
Investigator(s)
Project Titel
van den Heuvel OA
Online cognitive training in Parkinson’s disease, MS and ECT Cognitive rehabilitation
Heuvel, O.A. van den Werf, Y.D. va de Koellinger, P.
Grant Support (VU/VUmc part) € 46.793,00 € 46.793,00
Funding Organization
Funding type
Program
1
Running period in months 12
Soma & Psyche VUmc/GGZ inGeest Soma-Psyche
1
12
ND
NMH
The molecular genetic architecture of educational attainment and its significance for cognitive health - EdGe Photon-counting detector
€ 1.870.135,00
ERC Consolidator Grant
2
60
NMH
€ 150.000,00
2
12
BIT
Verhage, M.
NeuroNanoChip
€ 149.475,00
ERC proof of concept H2020 ERC-PoC-2014
2
18
BMHD
Boomsma, D.I.
M3: Molecuul, mens en maatschappij Hersenstimulatie stichting
€ 13.867,00
KNAW
2
3
NMH
€ 4.000,00
KNAW
2
18
BIT
Multi-level brain criticality as a mechanism of complex variability in perception and learning
€ 219.170,00
2
48
BMHD
A prison for the mind: Limiting neuronal plasticity involving the extracellular matrix NUDAD
€ 1.500.000,00
NWO ‘Research Talent’ Social Sciences, Netherlands Organization for Scientific Research (NWO, 406-15256). NWO VICI
2
60
NMH
2
60
ND
Linkenkaer-Hansen, K.
NBT Analytics --Integrating knowledge
€ 100.000,00
Kooij, G. Dijkstra, C.D.
A dysfunctional brake on neuro-inflammation drives disease progression in MS Imaging the Retina for Early Alzheimer Diagnosis (I-READ). Ludwig and the brain
€ 250.000,00
NWO-Food Cognition Behaviour 2015 Pre-seed loan from Innovation Exchange Amsterdam (IXA) Project funding
€ 749.000,00
STW HTSM
2
48
BIT
€ 150.000,00
The art of impact-grant
2
16
BIT
Multimodality and multiparametric PET/MRI analysis for enhancing diagnosis, prognosis and response prediction in advanced stage head and neck cancer. Pathological substrate of clinical variability in AD Identification of molecular and genetic mechanisms in familial Lewy Body Dementia: a novel approach
€ 500.000,00
ZonMw (IMDI)
2
48
BIT
€ 850.000,00
ZonMW Memorabel ZonMW Memorabel
2
48
ND
2
48
ND
Mansvelder, H.D.
Werf, Y.D. van de Sack (UM) Aleman (RUG) Sommer (UU) Linkenkaer-Hansen, K.
Spijker, S.
Flier, W.M. van der Scheltens, Ph.
Boer, J.F. de Werf, Y.D. van de Kamp, D. van der (foundation Ludwig) Boellaard, R.
Bouwman, F. Berg, W.D.J. van de Berg, W.D.J. van de
€ 1.100.000,00
€ 80.000,00
123
2
BMHD
2
NI
Annual Repprt 2015 - Appendices
Investigator(s)
Project Titel
Vies, S.M. van der Jong, F.J. de (ErasmusMC)
Development of Biomarkers enabling Early and Accurate Differential Diagnosis of Dementia Brain connectivity the missing link between amyloid and clinical symptoms Dementia with Lewy bodies and Alzheimer’s disease: an unfortunate couple? Lipids in AD (1 PhD)
Tijms, B. Flier, W.M. van der Scheltens, Ph. Lemstra, E. Flier, W.M. van der Scheltens, Ph. Rozemuller, J.M. Martinez, P. (UMC Maastricht) Verhage, M. Smit, A.B. Geurts, J.J.G. Hulst, H.E.
Schenk, G. Uitdehaag, B.M.J. Heine, V.M. Knaap, M.S. van der Heine, V.M. Knaap, M.S. van der Vries, H.E. de Flier, W.M. van der Scheltens, Ph. Sobrino (St Compostela, Spain) Wiel, M.A. van de Martinelli, E. (University of Parma) Penninx BW
Posthuma, D. Sullivan, P.F. (Karolinska Institutet) Veltman DJ
Smit, A.B. Sullivan, P.F. (Karolinska Institutet) Verhage, M. Sullivan, P.F. (Karolinska Institutet)
Grant Support (VU/VUmc part) € 35.000,00
Funding Organization
Funding type
Program
2
Running period in months 36
ZonMW Memorabel (PRODIA)
€ 150.000,00
ZonMW Memorabel fellowship
2
24
ND
€ 150.000,00
ZonMW Memorabel fellowship
2
24
ND
€ 230.000,00
ZonMW Memorabel grant Broad
2
36
ND
3
12
BMHD
€ 53.494,00
Dance for Health
3
15
NI
€ 1.477.020,00
3
48
NI
3
36
BMHD
ND
Broad Synapse Annotation Het behandeleffect van een cognitief dansprogramma tegen cognitieve klachten bij MS facing MS progression
€ 110.800,00
Glia progenitor cell transplantation for Vansihing White Matter Disease Patient-derived Glia precursor cell therapy for Vansihing White Matter Disease PANA
€ 300.000,00
Dutch MS reserach foundation ELA
€ 250.000,00
ERARE
3
36
BMHD
€ 762.250,00
EU Horizon 2020
3
48
NI
BD2Decide
€ 760.937,00
EU Horizon 2020
3
40
BMHD
GLOID: Genetics and lifestyle origins of Inflammation in Depression COSYN: Comorbidity and Synapse Biology in Clinically Overlapping Disorders PREDICT study: predicting the response to antidepressants in patients with depression in primary care by using an emotional response task COSYN
€ 133.199,00
EU Horizon 2020
3
16
NMH
€ 250.000,00
EU Horizon 2020
3
60
BMHD
€ 377.520,00
EU Horizon 2020 Framework Programme for Research and Innovation – SME funding EU Horizon large scale
3
3
60
BMHD
COSYN
€ 800.000,00
EU Horizon large scale
3
60
BMHD
€ 800.000,00
124
NMH
Annual Report 2015 - Appendices
Investigator(s)
Project Titel
Flier, W.M. van der Scheltens, Ph. Duijn, C. van (Erasmus MC) Scheper, W. F. Re, F. (University Milano Bicocca)
EADB
Barkhof, F. Alexander
Killestein, J. Bugiani, M. Wolf, N.I.
Mansvelder, H.D. Berg, W.D.J. van de Chartier-Harlin, M.C. (Univ. Lille) Vries, H.E. de Engelhardt (Bern, SwitzerlandO Vries, H.E. de Stankoff, B. (INSEM, Paris) Vries, H.E. de
Geurts, J.J.G. Hulst, H.E. Boomsma, D.I. Boomsma, D.I. Posthuma, D. Keller, M.C. (IBG, Colorado) Salomons, G.S. Smith, D.E.
Heuvel, O.A. van den Werf, Y.D. va de Berendse, H.W. Heuvel, O.A. van den Foncke, E.M.J.
Grant Support (VU/VUmc part) € 620.000,00
Funding Organization
Funding type
Program
3
Running period in months 36
EU JPND 2015
Development of a Novel Multicellular In Vitro Model of Alzheimer’s diseaselike Blood-Brain Barrier Data-driven models for Progression Of Neurological Disease (PHC-02-2015): Understanding disease: systems medicine Individuele dosering van het Msmeidcijn natalizumab Conditional boosting of transplanted heamtopoietic stem cells: a study on improvement of therapy in metachromatic leukodystrophy Human neuron physiology Splicing in Alzheimer’s and Parkinson’s disease
€ 46.732,00
EU JPND grant
3
36
ND
€ 465.873,00
EuroPOND
3
BIT
€ 200.000,00
Hersenstichting
3
NI
€ 49.726,00
Hersenstichting
3
12
BMHD
€ 640.000,00
3
24
NMH
€ 150.000,00
Human Brain Project - H2020 ISAO
3
36
ND
BtRAIN
€ 255.000,00
ITN Marie Curie
3
48
NI
Imaging MS
€ 12.500,00
MS Progessive MS Alliance
3
12
NI
Dynamic microglia imaging
€ 350.000,00
3
24
NI
MS Netwerk
€ 19.670,00
Multiple Sclerosis Innovation (GMSI) award Nieuw Unicum
3
12
NI
Social regulation of gene expression Psychometric and genetic assessments of substance use Estimating the Frequencies and Population Specifics of Risk Alleles Diagnose van vitamine B12 deficiëntie door middel van de bepaling van intracellulair vitamine B12 concentraties in erythrocyten met behulp van UPLCMS/MS methode. Online cognitive training in Parkinson
€ 260.000,00
NIH
3
60
NMH
€ 235.500,00
NIH
3
60
NMH
€ 72.000,00
NIH-US
3
36
BMHD
€ 15.000,00
Noyon's stipendium: Desiree Smith
3
12
BMHD
€ 39.896,00
Parkinson Vereniging
3
30
ND
Sleep and mood disorders in PD
€ 80.000,00
Parkinson Vereniging
3
Neurophysiological determinants...
€ 39.609,00
Parkinson Vereniging
3
125
ND
ND 12
ND
Annual Repprt 2015 - Appendices
Investigator(s)
Project Titel
van den Heuvel OA
Online cognitive training in Parkinson’s disease IMSVC
Petzold A. Calabresi, P. (John Hopkins, USA) Wolf, N.I.
Grant Support (VU/VUmc part) € 39.896,00 € 25.000,00
Funding Organization
Funding type
Program
3
Running period in months 36
Parkinson Vereniging Progressive MS Alliance grant
3
12
NI
NMH
Conditional boosting of transplanted hematopoietic stem cells: a study on improvement of therapy in metachromatic leukodystrophy Quantitative MRI in MLD
€ 49.726,00
Research grant
3
12
BMHD
€ 44.306,00
Research grant
3
12
BMHD
Longitudinal DLB cohort
€ 365.591,00
Stichting Dioraphte
3
36
ND
Does MS grey matter atrophy progress faster in regions with more damage in connected white matter? Development of a system to automatically annotate regions of diuffusely abnormal white matter The role of the insula in cognitive symptoms in early Parkinson’s disease De invloed van afwijkende steuncellen op zenuwcellen in de hersenen van kinderen met de ziekte Vanishing White Matter Genetic and molecular mechanisms in schizophrenia Project Classen
€ 242.550,00
Stichting MS Research
3
48
NI
€ 4.500,00
Stichting MS Research
3
12
NI
€ 130.000,00
3
36
ND
€ 60.000,00
Stichting Parkinson Fonds Stichting Zeldzame Ziekten Fonds subsidie
3
36
BMHD
€ 812.000,00
SUN
3
48
BMHD
€ 200.000,00
SUN addendum
3
48
BMHD
SUN
€ 1.100.000,00
SUN VU - Karolinksa collaboration
3
48
BMHD
Abeta detection with biosensors CODA-2 (additional WPs)
€ 6.868,00
TNO
3
€ 466.786,00
4
12
ND
Scheltens, Ph. Prins, N. Weering, J. van
MAP38K clinical trial
€ 796.193,00
Boehringer Ingelheim Pharma GmbH & Co. KG EIPharma
4
24
ND
Ultrastructural analysis of exosome preps
€ 51.444,00
4
6
BMHD
Geurts, J.J.G. Hulst, H.E. Boer, J.F. de
Multiple Screener
€ 58.000,00
EM project on exosomes with Janssen Prevention Center Genzyme
4
12
NI
Retinal imaging
€ 450.000,00
4
48
BIT
Vies, S.M. van der
Inflammation as a therapeutic target in AD
€ 41.000,00
4
4
ND
Hoozemans, J.J.M. c.s.
Anti Tau
€ 51.444,00
Heidelberg engineering Immunovo BV. The Netherlands Janssen Prevention Center
4
18
ND
Wolf, N.I. Flier, W.M. van der Scheltens, Ph. Lemstra, E. Vrenken, H. Pouwels, P.J.W.
Vrenken, H. Platel, B. (RadboudUMC) Berg, W.D.J. van de Jong, F.J. de (Erasmus MC) Klok, M.D. Knaap, M.S. van der
Verhage, M. Smit, A.B. Verhage, M. Smit, A.B. Sullivan, P.F. (Karolinska Institutet) Veerhuis R Flier, W.M. van der Scheltens, Ph.
126
NMH
Annual Report 2015 - Appendices
Investigator(s)
Project Titel
Weering, J. van c.s.
EM on Tau
Grant Support (VU/VUmc part) € 51.444,00
Funding Organization
Funding type
Program
4
Running period in months 18
€ 147.420,00
Janssen Prevention Center Janssen Stellar
Flier, W.M. van der Scheltens, Ph. Duijn, C. van (Erasmus MC) Scheper, W. c.s.
IMMEDIAD
4
18
ND
UPR
€ 528.420,00
Janssen Stellar
4
18
ND
Berckel, B. van c.s.
TAU
€ 485.550,00
Janssen Stellar
4
18
ND
Salomons, G.S.
€ 60.000,00
Lumos Pharma
4
12
BMHD
€ 102.684,00
Lysosomal Therapeutics
4
6
ND
€ 422.500,00
24
BIT
4
12
BMHD
Hoozemans, J.J.M. Smit, A.B.
Target validation Phase IV
€ 386.000,00
4
8
ND
Veerhuis R
Enhancement of Abeta uptake by microglia REVEAL study- Central analysis of MRI Scans Antibodies for alphasynuclein (extension project) Precise segmentation of GM structures in MS patients Study of synaptic and molecular mechanism of Levetiracetam and related SV2A binding compounds Childhood white matter disorders Childhood white matter disorders Erfelijke overeenkomsten tussen frontotemporale dementie, psychiatrische aandoeningen en ALS
€ 76.560,00
Novartis Pharma B.V. research grant Nutricia PhD research project(4th year) ONO pharmaceutical s Probiodrug AG
4
Verheijen, M.H.G.
Creatine transporter deficiency Glucocerebrosidase and Acid ceramidase in human brain tissue samples of PD patients and controls Development of calibrated brain atrophy rate measurement in MS CognitionNet/Nutricia
REVEAL (Biogen) Roche
4
48
NI
4
12
ND
Teva Pharmaceutical Europe B.V. UCB S.A.
4
36
BIT
4
12
BMHD
De Vos-van der Steen B.V. Private donation Private support program
5
12
BMHD
5
60
BMHD
5
36
ND
Berg, W.D.J. van de
Vrenken, H. Barkhof, F.
Geurts, J.J.G. Berg, W.D.J. van de Barkhof, F. Vrenken, H. Toonen, R.F.G.
Knaap, M.S. van der Knaap, M.S. van der Pijnenburg, Y.A.
€ 131.000,00
€ 92.000,00 € 29.000,00 € 500.322,00 € 273.720,00
€ 25.000,00 € 600.000,00 € 300.000,00
127
4
ND
NMH