Lato and Guso

Hypoglycemic Marvels

/ Schinker Pahugot

In pursuit of groundbreaking discoveries, passionate and tenacious senior high school students from the Science and Technology Education Center (STEC) embarked on an intriguing journey to investigate a specific issue. Their mission: A Comparative Analysis on the Hypoglycemic Activities of Lato (Caulerpa lentillifera), (Caulerpa racemose), and Guso (Eucheuma denticulatum) on Alloxan-Induced ICR Mice. Simply put, this research seeks to evaluate and contrast the hypoglycemic effects of extracts derived from the Lato and Guso plants. With the noble aim of uncovering potential potent anti-diabetic medications, these budding scientists delve into the captivating world of marine flora. Could the primordial secrets hidden within Lato, Guso, and Eucheuma denticulatum hold the key to conquering diabetes and its grave health risks? Their unwavering pursuit of better health promises to unveil fascinating possibilities that may revolutionize diabetic care.

Diabetes is a relentless, chronic condition that has a devastating impact on people's health. This condition is caused by either the pancreas' inability to create enough insulin or the body's inability to effectively use this vital hormone, which results in high blood sugar levels. Despite advances in scientific research, it is still difficult to adequately control diabetes. Early therapies included insulin injections, rigorous food restrictions, and, astonishingly, in desperate times, even opium experiments. As a result of humanity's never-ending search for answers, we have traveled to every part of the planet. This has caused us to consider an intriguing possibility: may the key to revolutionizing diabetes treatment be hidden in the enigmatic depths of our oceans?

The process started as 25 seven-week-old ICR mice were divided into five groups, including a negative control which are treated with water, a positive control which are treated with metformin, and three experimental groups which are treated with the extract from Lato and Guso. Alloxan, a chemical, was used to induce diabetes in the mice through intraperitoneal injection. The extract used were obtained from each seaweed sample using a maceration process in 70% ethanol then evaporated on a rotary evaporator. The blood glucose of each mice were measured using a glucometer through tail-snip blood extraction at three different points: baseline blood glucose level, after Alloxan induction, and after treatment with the Lato and Guso Extracts.

The study commenced with 25 ICR mice aged seven weeks were carefully split into five groups to begin the investigation. Water was given to the first group as a negative control, and metformin was given to the second group as a positive control. For the experimental therapy, Lato and Guso seaweed extracts were given to the remaining three groups. The Alloxan substance was injected into the mice's abdomens and utilized to develop diabetes in them. The extracts from Lato and Guso need a rigorous procedure to get. The seaweed samples were macerated in 70% ethanol before being dried with a rotary evaporator. The mice's blood glucose levels were monitored at three critical times: before Alloxan-induced diabetes, after Alloxan-induced diabetes, and after administration of the Lato and Guso extracts. A little amount of blood from their tails was drawn and tested for glucose using a glucometer. The researchers want to learn a lot about the possible impacts of Lato and Guso extracts on the management of diabetes by tracking these variations in blood glucose levels. The results of the investigation revealed surprising findings after careful observation. In contrast to those given with the Guso extract, mice treated with the Lato extract showed the most notable reduction in blood glucose levels. The scientists' comprehensive statistical analysis, which confirmed a sizable difference in blood glucose levels between the various groups and gave their conclusions more credibility, was carried out to support their findings. These persuasive findings provide convincing proof of the observed alterations and offer important new information about the possible advantages of Lato and Guso extracts in controlling blood sugar levels.

The study's results will ignite a glimmer of hope in the realm of diabetes treatment, holding up the possibility of a paradigm-shifting discovery. The early signs of Lato and Guso extracts as effective anti-diabetic drugs are definitely encouraging, even though more extensive research is required to validate and improve these results. As they pave the path for a better and healthier future for those living with diabetes, these young scientists' unflinching dedication and labor of love are deserving of appreciation. There is a tangible excitement among scientists as they avidly explore this uncharted region that their work will result in revolutionary improvements in the treatment of diabetes that will improve the lives of millions of people around the world.