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INNOVATION FOR INDEPENDENCE
ISSUE 67 June/July 2009 £6.95
Firm turning to spider’s web science By Dominic Musgrave AN Oxfordshire company is aiming to use the science behind spiders' webs to help rebuild people's joints. Orthox has developed a silk biomaterial that can regenerate damaged cartilage and bone tissues. The company's CEO Nick Skaer told Assistive Technologies that the technology, which imitates the strength and resilience of spiders' silk, could save the NHS hundreds of millions of pounds. He added: “Spider's silk is one of the strongest substances known to man and, combined with being extremely elastic, it is not only very strong but also very robust. We are looking at developing a material based on this to fix cartilages because more operations of this type to repair them are taking place each year. “Once inside the human we hope the material will repair the damaged tissue and encourage new cartilage to grow around it and replace it." The company has been studying the silk produced by a poisonous species of spider from Australia, but because
each spider can only produce about 20 metres of silk in one go, silk worms, which are more prolific spinners, are used instead. The company plans to turn liquid silk into silk sponges, which will be used to replace the damaged cartilage. Based on a decade of research by Oxford University scientists, the absorbable implant takes over the function of the damaged tissue, removing the need for permanent plastic or metal prosthesis. Nick added: “The model is working how we would want it to and we are pretty close in the development stage. We received £1.6m from the Wellcome Trust to fund the development and design process. This is a three-year project and in two-and-a-half we hope to be in a position where we are using the materials in humans. In future we hope to develop products for other serious orthopaedic problems such as spinal disc repair and bone regeneration.” Knee replacements now cost the NHS more each year than total hip replacements, estimated at nearly £1 billion by 2010.
Five-year-old Ellie Challis made headline news when she became the youngest person to be fitted with Flex Run feet, after losing her limbs to meningitis. Inside, Bob Watts of fitters Dorset Orthopaedic shares his experience of the project with Assistive Technologies. Picture: www.worldwidefeatures.com Full story, Page 14