In light of the Jan. 22 anniversary of the U.S. Supreme Court decision Roe v. Wade, the January 2009 issue of Columbia features a series of articles about defending the sanctity of human life. It highlights a few of the many ways in which Knights are working tirelessly to build a culture of life, from assisting pregnant women in need to giving a voice to the voiceless in the public square. Plus, Supreme Knight Carl A. Anderson discusses the essential role of the laity in renewing and evangelizing the secularized culture.