بسم ا الرحمن الرحيم
RED CELL MORPHOLOGY- III Dr. Akram Al-Hilali 2010
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POIKILOCYTOSIS Any change from normal biconcave disc with
smooth round edges is a type of poikilocytosis Some kinds of poikilocytosis are very specific and others are non-specific, occurring in many conditions. Adding poikilocytosis type to anisocytosis, polychromasia, Hb and MCV levels as well as clinical information will make a diagnosis likely. 08/13/14
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POIKILOCYTOSIS RED CELL BOUNDARIES
OVALOCYTOSIS & ELLIPTOCYTOSIS
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CRENATION Generalized in severe dehydration,
small sample and old sample. Small numbers seen in renal and liver disease Usually seen with burr and acanthocytes
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ACANTHOCYTES & BURR CELLS Acanthocytes are seen in liver disease. Can be congenital and shows from birth
with abnormalities in lipid metabolism Burr cells are seen in small numbers in chronic renal disease. Crenation, burr cells and acanthocytes may be seen together in liver and renal diseaseز The three can be seen after splenectomy. 08/13/14
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TEARDROP CELL (PEAR) ď Ž Seen in many different
conditions ď Ž They can be accompanied by oval cells, in which case it could be a serious condition: like marrow occupying disease, megaloblastic anemia and thalassemia major 08/13/14
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