Activities report 2012 by Fiotec

Board of Curators Jorge Carlos Santos da Costa (chairman) - VPPIS Adolfo Horacio Chorny – Head researcher retired Alejandro Marcel Hasslocher Moreno (until August) - IPEC Christian Maurice Gabriel Niel - IOC Francisco Inácio Pinkusfeld Monteiro (until August) - ICICT João Luiz de San Tiago D. Barbosa Quental - Ombudsman - Fiocruz Presidency Jorge Souza Mendonça (from August) - Farmanguinhos Marília Santini de Oliveira (from August) - IPEC Rosamélia Queiroz da Cunha - Inca

Audit Committee Gilvan Ferreira (Chairman) - Dirad José Damasceno Fernandes - VPGDI Junilton Barbosa Silva - Bio-Manguinhos

Executive Board Maurício Zuma Medeiros – Executive officer Mansur Ferreira Campos - Financial officer Roberto Pierre Chagnon - Administrative officer Valéria Morgana Penzin Goulart - Technical officer

General Management Adilson Gomes dos Santos

SUMMARY Presentation ................................................................................................... 1 - Institutional information 1.1 - Introduction ................................................................................................ 1.2 - Activity ...................................................................................................... 1.3 - Administrative Structure ............................................................................... 1.4 - Operational Structure ................................................................................... 1.5 - Organization Chart .......................................................................................

4 7 7 8 8 9

2 - Year Highlights 2.1 – Project Management ................................................................................... 11 2.1.1 – Project Transaction ................................................................................ 11 2.1.2 – Account Rendering ................................................................................ 11 2.1.3 – Project Conciliation ............................................................................... 11 2.2 – Special Projects Management Consolidation ................................................ 11 2.3 – Office assembly in Brasília ........................................................................ 11 2.4 – International funding prospection .............................................................. 11 2.5 – Scholarship grant process reformulation ..................................................... 12 2.6 – Social inclusion project ............................................................................ 12 2.7 – Internal benefits ..................................................................................... 12 2.8 – Citizen Company certificate......................................................................... 12 2.9 – Electronic Auction Implementation ................................................................. 12 2.10 – Implementation of panel with Logistic performance indicators ....................... 12 2.11 – Revision in the ticket request process ........................................................... 12 2.12 – Participation in the OAB-RJ subcommittee ...................................................... 13 2.13 – National meeting of support foundations ...................................................... 13 2.14 – Visits to the institutional website ................................................................. 13 2.15 – 14th anniversary and launch of the English website ..................................... 13 2.16 – Implementation of selective paper collection .............................................. 13 2.17 – Inclusion of Access to Information link in the website .................................... 14 2.18 – Solidary Fiotec .......................................................................................... 14 2.19 – Fiotec 2.0 Event ....................................................................................... 14 2.20 – Implementation of the Electronic Document Management (GED) system ....... 14 2.21 – Other investments in technology .............................................................. 14 2.22 – “Olá, muito prazer!” Portal ........................................................................... 15 2.23 – Quality Management System (SGQ) ......................................................... 15 2.24 – Support to event of Cancer Foundation .......................................................... 15 3 - Activities 3.1 - Number of projects managed ..................................................................... 17 3.2 - Information on projects started in 2012 ...................................................... 17 3.3 - Funding agents ........................................................................................ 72 4 - Budget and financial resources management 4.1 - Project financial handling .......................................................................... 75 4.2 - History Data ............................................................................................ 77

APRESENTAÇÃO

Work focused on improving the services provided The year of 2012 was of hard internal work in the Foundation for the Scientific and Technological Development (Fiotec). After defining the major guidelines of the new Executive Board in 2011, focused on value adding, quality, result and transparency, we have been working on several fronts to ensure improved work conditions for collaborators, the progress and modernization of management processes and, hence, the refinement of services provided. One of the highlight initiatives for the management consolidation in the year was the creation and implementation of the Quality Management Program, aligned with the Oswaldo Cruz Foundation (Fiocruz) Program, and with the main objective of preparing Fiotec to achieve the ISO (International Standardization Organization) 9001:2008 certification. As far as politics regards, Fiotec was responsible for the organization of the 30th National Meeting of Support Foundations for Higher Education and Scientific and Technological Research Institutions - Confies (2012). As contribution to the consolidation of Confies (Support Foundations for Higher Education and Scientific and Technological Research Institutions), Fiotec presented proposals for adding value to results, increasing integration between affili-ates and for increasing the pro-activity of the institution’s Board in the dialogue with public agents of the Executive and Legislative powers, aiming at reverting the complex set of regulations reducing the foundations support capacity. In the social area, Fiotec has also had an important role. The partnership with Empreender Institute and Benjamin Constant Institute (IBC) was made for offering social and professional qualification to youngsters with disability as well as for providing more opportunities to enter in the job market. In the end of the year, the institution was granted the Citizen Company Certificate by the Regional Accounting Council (CRC-RJ), with the support of the Industries Federation of the State of Rio de Janeiro (Firjan) and of the Trade Federation of the State of Rio de Janeiro (Fecomercio), based on the analysis of its Balance Sheet and its accounting statements. Much dedication was also paid for achieving its major objective: the support to Fiocruz’s projects is well represented on the pages of this report. There were 159 new projects throughout the year, whose relevant information is included in chapter 3, added to those already ongoing. In the end of 2012, a total of 439 projects of Fiocruz counted on Fiotec’s support. The commitment to transparency is also reported. Overall, 90 account renderings were presented and three audits were performed. Fiotec’s mission is noble. Every year, its capacities are strengthened for the result of its work in supporting Fiocruz projects to be successful in favor of the society. That is what is evi-denced and is found on the pages of this report.

Maurício Zuma Medeiros Executive Director

1.1 – Introduction The Foundation for Health Scientific and Technological Development (Fiotec) was founded in 1998 named Technological Education, Research, Development and Cooperation to the National Public Health School (Fensptec), originally for supporting projects of the Sergio Arouca National Public Health School (Ensp), of Oswaldo Cruz Foundation (Fiocruz). Under resolution of the Extraordinary Plenary Meeting of the III Internal Congress in 2000, the existence of a single support foundation for the institution’s set was determined. This way, Fiotec received its current name and started supporting projects of all unities of Fiocruz. Acting for more than 10 years, Fiotec is duly registered and accredited by the Ministry of Education (MEC) and the Ministry of Science, Technology and Innovation (MCTI) for acting as support foundation. Moreover, it was granted the Declaratory title of Public Utility by the Government of the State of Rio de Janeiro and the qualification in the health area as Social Organization (OS), by the Local Government of Rio de Janeiro. According to the National Council of Scientific and Technological Development (CNPq), the institution is able to import goods for the scientific and technological research, in accordance with Act 8,010/90. It has also been given the certificate of Citizen Company by the Regional Accounting Council (CRC-RJ), in partnership with the Industries Federation of the State of Rio de Janeiro (Firjan) and the Trade Federation of the State of Rio de Janeiro (Fecomércio). Fiotec has the DUNS Number - Data Universal Numbering System. The number is internation-ally acknowledged as common identifier of companies with EDI (Electronic Data Interchange) and in the foreign trade transactions. Only with this number is possible attaining the registra-tion with the Central Contractor Registration (CCR) which has migrated on July 30, 2012 to a new system: SAM (System for Award Management), that governs all the contracts made with federal agencies of the United States of America (USA). The DUNS Number certificate is granted by the D&B group, which is considered one of the greatest companies in credit risk analysis and financial evaluations. Mission Our mission is to provide services of logistic, administrative support and financial management for the projects developed by Fiocruz, in the science, technology and innovation areas, in several categories: education and research, health goods and inputs production, health reference services, health information, institutional development and promotion of technical and scientific events; and, as Social Organization (SO), in projects comprising basic service and promotion to health, hospital education and management, in Fiocruz partnerships with Government agencies. Vision To increase, every day, the quality of our activities, processes and skills and excel as support foundation, in order to make feasible the health technology innovation and the qualification of the human resources involved, helping improve the society’s quality of life. Values Integrity, Transparency, Efficiency and Ethics.

1.2 - Activity The first Agreement between Fiocruz and Fensptec was signed on September 4, 1998, which regulated the relationship between the entities. The second Agreement with the foundation, already with its new name – Fiotec – was signed in 2005 (no. 05/2005). The third Agreement (no. 18/2008), effective nowadays, provides the activities, projects and programs develop-ment to be in accordance with Fiotec’s institutional mission and to be previously approved by Fiocruz Over the last decade, Fiotec has developed the skills required to offer: • Transparency and credibility: projects accurate and updated data to partners; moreover, the institution is audited every year by the Public Prosecutors’ Office. • Customized project management: working with the current issues in several areas, including public health services, research and development on health and neglected diseases, the promotion of the universal access to health, adapting to the needs of each partnership. • Professional team specialized in project management: offering a reliable and proper struc-ture for our partners to act in their projects. • Administrative and financial autonomy: essential agility for the project management and financial execution.

Fiotec’s contribution for the execution of projects developed by Fiocruz comprises all efforts in the following areas: education and research; health goods and inputs production; health reference services; health information; institutional development; and promotion of technical and scientific events.

1.3 - Administrative structure Board of Curators Body for higher deliberation and instruction of Fiotec. Its members are nominated by Fiocruz’s President and are to be attested by its Deliberative Board. This body is to approve and nominate the members of the Executive Board. Audit Committee Fiotec’s economic and financial management inspection body. Every year, the Board of Cura-tor is submitted the annual report, the balance sheet and the other financial statements, duly audited. In 2012, it started evaluating the balance sheet every quarter. It is also nominated by the Presidency and attested by Fiocruz’s Deliberative Council. Executive Board The members of the Executive Board are nominated by the Board of Curators and approved by Fiocruz’s Deliberative Board. It is responsible for guiding and monitoring Fiotec’s administrative and financial activities, the institution’s strategic development by implementing new political and administrative efforts as well as for intermediating the relationship between Fiotec and Fiocruz. General Management The general manager, nominated by the Executive Board, is responsible for the performance of Fiotec’s administrative and financial activities and of other activities assigned by the Execu-tive Board.

1.4 - Operational structure Fiotec reinforces every year its professional team for achieving the mission of supporting Fi-ocruz’s projects. In 2012, the staff totalized 285 people, distributed among the headquarters and two offices: one in the Sergio Arouca National Public Health School (Ensp) and other in the Immunobiological Technology Institute (Bio-Manguinhos) – both in the Manguinhos campus of Fiocruz. In May, the Fundo Global office, existing since 2007, was closed due to the project conclusion, and, in the end of the year, an office was opened in Brasília-DF. Addition-ally, Fiotec relied on 5,103 professionals acting directly on Fiocruz’s projects. The organizational structure is divided into six managements and two advisories: Legal Advisory Area responsible for legal instructions, opinions, and construction of legislation, contract analysis, civil and labor questions. Technical Advisory Area having as general duties supporting the Executive Board’s demands, Fiotec’s Communi-cation (internal and external); planning and monitoring of the institution’s budget; and the revalidation of titles and certifications required for Fiotec’s operation. Projects Management Responsible for projects management in all phases and for the communication among the project coordination, the other areas of Fiotec and the financial agents. Special Projects Management The efforts of this organizational unit are developed based on the cooperation and alliances between public and private, national and international institutions, aimed at developing knowledge, practices, processes and innovative products. Human Resources Management Responsible for the organization, planning and performance of all works and activities relat-ed to the people strategic management, labor routines and worker’s health, in the scope of both the Fiotec’s headquarters and the project professionals.

9 Logistic Management Responsible for managing the activities developed in the following sectors: Purchases; Purchase Monitoring; Registration, Contracts and Tender Analyses; General Services; and Records. Controllership Management As it is the department holding all the financial and accounting information of the organization, the Controllership has to identify, plan, organize, control and manage all risks and costs. Information Technology Management In addition to the most common duties to the technology, telecommunications and asset administration areas, the area is responsible for mapping and controlling the processes and documents (Quality Management).

1.5 â&#x20AC;&#x201C; Organogram

11 Fiotec managers set 57 internal action plans, contemplating improvements in all sectors. They comprise solutions related to the institution’s human resources, work tools, and infrastructure issues. In 2012, there was a 35% progress in the execution of those plans, while the ex-pectation for the period was of 25%. Many of the highlights detailed on the next pages are results of that work, part of the strate-gic planning set by the current Executive Board in July 2011, when the members took up the office. Besides consolidating the teams’ interaction – as different sectors of Fiotec are in-volved –, the execution of those plans stresses the institution’s commitment to the excellence in services provision.

2.1 – Project Management

2.1.1 – Project Transaction

A equipe de Iniciação de Projetos foi fortalecida ao longo deste ano. Ao todo, 217 projetos foram negociados por este setor, dos quais 64 entraram em execução. Outros 76 projetos, cuja negociação foi iniciada ao longo de anos anteriores, começaram a ser executados neste ano, totalizando 140 novos projetos.

2.1.2 – Accounts Rendering

Outra equipe fortalecida ao longo do ano foi do setor de Prestação de Contas, o que rendeu bons resultados: foram 90 prestações realizadas ao longo de 2012, sendo 63 com órgãos externos e 27 com a Fiocruz.

2.1.3 – Project Conciliation

Projects Management implemented an effort expanding the transparency and reliability of the balances of its projects presented in the portal, accessible by the coordinator through the institutional website. It is the projects conciliation, a methodology created internally for detailed check of expenses made by all projects, in order to ensure the reports issued not to in-clude inconsistencies.

2.2 – Special Projects Management Consolidation

In addition to the 19 new strategic projects started in 2012, other projects with the same characteristics and that were already in execution in Fiotec were transferred to this organiza-tional unit. This way, the team started managing 63 projects, 48 of which being executed by the International Projects Coordination. The Projects Initiation sector was also implemented in the area.

2.3 – Office assembly in Brasilia

In the end of the year, an office of Fiotec was implemented in Brasilia due to the need for a more adequate support to the projects of the Brasilia Regional Board (Direb) and to the growing number of large sized projects developed by Fiocruz in partnership with the Ministry of Health.

2.4 – International funding prospection

The International Projects Coordination, in partnership with the Communication, implement-ed a room in the Fiotec’s website to disclose the international funding opportunities, focused on projects in the health area. The purpose is offering the project coordinators the service of search for opportunities, expanding Fiotec’s activity and, thus, seeking new partners for Fiocruz.

2.5 – Reformulation of the scholarship grant process

The item on scholarship grant specified in the Fiotec’s Execution Manual was reformulated with new rules, in the scope of the Institutional Program for Support to the Science and Technology Activities and Innovation. The purpose is ensuring increased technical and legal security to the projects, students, coordinators and to the institution itself, according to the standards provided by decree no. 7423/10.

2.6 – Social inclusion project

Empreender Institute, Benjamin Constant Institute (IBC) and Fiotec made a partnership, under the guidelines of the Ministry of Labor, for a social and professional qualification and training on English for conversation aimed at youngsters in need and disabled people. Fiotec funds and monitors the project, offering assistance whenever required.

2.7 – Internal benefits

Fiotec started implementing some important benefits over the year: start of operation of the institution’s own collective transportation, for the wellbeing of collaborators; contracting of a consultancy company for reformulation of the Job and Salaries Plan, so as to offer the employees a career perspective and fit the functions performed in the institution to the job market reality; and the Professional Qualification Program, aiming at developing the professionals’ skills. The Corporate Communication and Writing course was also held, for improving the knowledge of collaborators on the Portuguese language.

2.8 – Citizen Company certificate Fiotec has been given the certificate of Citizen Company by the Regional Accounting Council (CRC-RJ), in partnership with the Industries Federation of the State of Rio de Janeiro (Firjan) and the Trade Federation of the State of Rio de Janeiro (Fecomércio). This certification proves that the information included in the trial balance sheet is under the requirements granting the institutions awarded the condition of social and environmental company.

2.9 – Electronic Auction Implementation

Fiotec’s purchasers participated in training at Banco do Brasil. This way, the financial institution’s website started being used for holding 100% tenders and 80% of price takings.

2.10 – Implementation of panel with Logistic performance indicators

This effort was the first step to set which indicators are required for the Purchase sector. The purpose is improving the performance of the activities performed and, hence, the services provision.

2.11 – Revision in the ticket request process

This is the first reorganization phase for the Tickets and Events sector, for reducing the stages existing in the flow between requesting and issuing tickets. The second phase includes the implementation of the self booking system.

2.12 – Participation in the OAB-RJ subcommittee

Fiotec started integrating the Inspection Subcommittee for the Senate Bill no. 619 of 2011, instituting the National Code for Science, Technology and Innovation, to govern all issues related to science, technology and innovation. The study, including the topics that should be included in the Bill, is organized by the Brazilian Bar Association (OAB) of Rio de Janeiro.

2.13 – National meeting of support foundations

An annual event held by the National Council of Support Foundations for Higher Education and Scientific and Technological Research Institutions (Confies), the 30th National Meeting of Support Foundations for Higher Education and Scientific and Technological Research Institutions (Confies 2012) was organized by Fiotec. Over the four days of the event (from November 26 to 29), the participants took part in nine workshops and five panels addressing relevant matters for the support foundations routine. The new presidency of the agency was chosen, as well as the venue for the 2013 meeting: Recife-PE. The proposal of a more effective activity of the Council before government and control agencies for simplifying the normative milestone and, hence, strengthening the foundations’ role and the results of the institutions supported was an important aspect of the event.

2.14 – Visits to the institutional website

Within one year, almost 230,000 visits were registered, which is a rather high number for an institutional and informative website. Furthermore, there were 85,000 single visits (i.e., of different users). A monthly external bulletin was also launched, including all the news published in the website for that period. It is sent to the project coordinators and heads of units of Fiocruz, in addition to some suppliers and other partners nominated by the managers.

2.15 – 14th anniversary and launch of the English website The foundation’s 14th anniversary was celebrated with the launch of the English version for the institutional website, whose purpose is to provide more transparency to the institution’s activity and allowing more interaction with international partners.

2.16 – Implementation of selective paper collection

The selective paper collection was implemented in Fiotec by the Dirac/Fiocruz Environmental Management, in order to contribute to the natural resources preservation. The cleaning employees were trained for dealing with the correct destination of the recyclable paper applicable cans content. In turn, the collaborators, participated in an on-site forum, when the problems caused by the wrong destination of garbage, the project goals and some ways of recycling at home were shown.

2.17 – Inclusion of Access to Information link in the website

A link was placed in the institutional website disclosing several data of the institution. This is in compliance with the Access to Information Act, providing that all agencies, public entities and non-profit private entities receiving public funds for performing public merit actions should make general or collective information available.

2.18 – Solidary Fiotec

Throughout 2012, three campaigns for blood donation and two for donating toys, clothes and other items were performed: • 2012 Christmas Campaign: 62 toys and 57 clothing items were collected. Besides, two kits with Christmas food products were donated. The items collected were donated to Educandário Romão Mattos Duarte, in Rio de Janeiro. • Children’s Day Campaign: 666 items collected, including 323 toys, 239 entertainment magazines and 104 books. The donations were given to the day care Sagrado Coração de Maria, in Rio de Janeiro. • Brazilian Blood Donator’s Day: twelve collaborators contributed to the campaign and went to Hemorio for donating blood. The transport was offered by Fiotec. The collaborators grouped themselves and repeated the effort other two times over the year.

2.19 – Fiotec 2.0 Event

Aimed at Fiotec collaborators and guests from Fiocruz, the event’s purpose was showing the challenges and advantages of an organization proposed to make its processes digital. The activity is included in the institution’s commitment to make its document digital, and showed the legal grounds for that change.

2.20 – Implementation of the Electronic Document Management (GED) system GED was developed in 2011, but it has started operating only in 2012. The system operation, making all the institution’s documents digitally available, resulted in agility and efficiency in the documents handling and search. It has also contributed indirectly to the improvement of some processes. Another important result was the dramatic reduction in the quantity of prints (about 60%), resulting in saving of paper, ink, equipment maintenance, and, hence, preservation of natural resources. The savings were in average of R$ 32,000 per month. For one year, the savings are of approximately R$ 384,000.

2.21 – Other investments in technology

Creation of the protocol system: the storage of all documents entry, exit, transfer and location records and the responsible persons started to be made online, providing more agility to the identification and, thus, more security.nça. Creation of the electronic invoice system: all invoices issued by Fiotec started being sent automatically to the Local Government of Rio de Janeiro or the State of Rio de Janeiro Treasury Department for the generation of NF-e (Electronic Invoice), which increased the process efficiency and safety. Creation of a purchase system: it is fully constructed and its next stage is homologation. The system is to automatize the entire purchase process, from purchase order forms filling to quotation, including the budget approval. Web scholarship system: under construction, this system is to speed up the grant, renewal and cancellation procedure for scholarships given by Fiotec. Moreover, it will apply parameterizable security criteria to reduce the risks regarding grants undue, beyond the limits and terms set.

15 Telephony restructuring: the phone center was reprogrammed. All DDD, IDD and mobile calls are now directed through Voice over Internet Protocol (VoIP), which reduced the amount of bills significantly. Over six weeks, a saving of R$ 7,330.40 was found. For one year, the estimate is of approximately R$ 63,500 in savings. Storage of e-mails in Microsoft’s cloud: Fiotec users’ e-mails are now stored in Microsoft’s cloud, instead of being in the local server. The option for changing was due to the benefits offered by the system, namely: greater storage capacity; mailboxes of up to 25Gb; increased security, ensured by Microsoft; and larger service availability, since Microsoft ensures 99.9% of operation.

2.22 – “Olá, muito prazer!” Portal The project, presented during Confies 2012, started being implemented. It aims at promoting and fostering the exchange of experiences between support foundations through a collaborative portal, to be used for discussing and sharing the problems of those institutions and finding possible solutions.

2.23 – Quality Management System (SGQ)

So as to achieve the ISO:9001 (International Organization for Standardization) certification, a committee was created for coordinating the implementation of the Quality Management System (SGQ) in Fiotec. It was the trigger for showing the technical skills in the different activities performed and adding value to the services offered by the institution. This way, the Processes and Documents Management (GPD) team, which was already working on the improvement of the institution’s processes, started integrating a new sector: Quality Management, which will fit Fiotec to the standards required for achieving the certification. For such, Fiotec relied on Fiocruz’s support, regarding the implementation, consultancy, training and distribution of materials with relevant information. In 2012, besides the team qualification plan, the analysis, standardization and updating process was started for the forms applied in the institution. Added to that, there was the construction and methodological alignment of process and documents.

2.24 – Support to event of Cancer Foundation

Fiotec supported the 4th “Com você, pela vida” Run and Walk, organized by the Cancer Foundation for encouraging the bone marrow donation. A group of collaborators participated in the event representing the institution.

3.1- Number of projects managed

3.2 - Information on projects started in 2012

In order to support, providing increased security and transparency to transactions, the premises applied in projects coding were changed: some of them were canceled and others were created. The measure became effective in the end of the year and the codes used before that change remained the same. Premises applied until December 2012: LIV

Free

INO

IN 1-97

FDI

Finep - Art.24

CFA

Funding Contract

CAC

Letter of Agreement

FPR

Finep - Auction

SPR

Auction

Premises valid from December 2012: FIO

Fiocruz

FEX

External sponsor

PPE

Projects with external Premises

CFA

Funding contract

CAC

Letter of agreement / Courses and seminars

ADP (INO/FDI/ FPR)

It governs the public administration in its purchases/contracting and addresses the matters related to the Acts 8,666/63, 10,520/02 and IN 01/97.

In addition to managing the 280 projects that started being developed in other years and continue ongoing, in 2012 Fiotec supported the start of 159 new projects, from the several units of Fiocruz, as described below. The list with the previous projects is found in the Fiotecâ&#x20AC;&#x2122;s website, link Access to Information.

19 Title: II/III phase clinical studies of the biodrug Alfapeginterferona 2B Code: BIO-001-LIV-12 - Official Number: 25386.001444/2011-77 Period: 12/27/2011 to 12/27/2014 Coordinator: Andrea Good Lima Couto Partnership: Fiocruz Objectives and results: Development of safer, more efficient treatments, with higher tolerance for treating hepatitis C. Title: Institutional development related to the implementation projects for functional strategies of BioManguinhos Code: BIO-002-LIV-12 - Official Number: 25386.000057/2012-02 Period: 02/24/2012 to 02/24/2014 Coordinator: Andrea Good Lima Couto Partnership: Fiocruz Objectives and results: The specialized services for institutional development aim at supporting the latest years accelerated growth of Bio-Manguinhos and the growing demand regarding complexity for the management area, providing the continuous improvement of organizational processes and higher efficiency in management. Title: Clinical research in Bio-Manguinhos Code: BIO-003-LIV-12 - Official Number: 25386.001122/2012-17 Period: 11/26/2012 to 11/25/2015 Coordinator: Andrea Good Lima Couto Partnership: Fiocruz Objectives and results: The project has several distinct efforts. One of them is the development of the meningitis B vaccine, the first resulting from a 100% national initiative to be produced by Bio-Manguinhos. The study is between II and III phases, consisting in the choice of the best concentration of the vaccine, for later attainment of product registration. Other activity is the development of the meningitis C vaccine. Its formulation is undergoing improvements. Later on, the clinical test will be started in public health units of Rio de JaneiroRJ and of BelĂŠm-PA. There is also the clinical study for assessing the immunogenicity and reactogenicity of the MMR vaccine (measles, mumps and rubella), which is totally made in Bio-Manguinhos, and the consistency in the production lots. Other effort is the validation of the quick test kit for detecting syphilis. Five thousand samples will be tested in five health centers of Rio de Janeiro. The study for testing the accuracy and reproducibility of the multitest kit based on the liquid micro arrangements platform, on the serologic screening of infections by HIV-I and HVI-II, HTLV-I and HTLV-II, HBV, HCV, Treponema pallidum and Trypanosoma cruzi in blood donators is also programmed. Finally, the project aims at assessing the safety of the Alfaepoetina (EPO) made by Bio-Manguinhos since 2006. This is the drug most used for treating anemia in patients with chronic kidney disease. Title: Implementation of a new management model for Bio-Manguinhos, due to the change of legal standard for the public company of private law Code: BIO-004-LIV-12 - Official Number: w/o no. Period: 12/04/2012 to 06/04/2014 Coordinator: Priscila Ferraz Soares Partnership: Fiocruz Objectives and results: Execution of institutional development activities related to the implementation of a new management model for Bio-Manguinhos, based on a legal standard for the public company of private law.

23 Title: From plan to policy: ensuring the right to health for all people in the prison system Code: DIREB-001-LIV-12 - Official Number: 25027.000072/2011-41 Period: 12/30/2011 to 12/30/2012 Coordinator: Maria Célia Delduque Nogueira Pires de Sá Partnership: Fiocruz Objectives and results: The creation of a National Health Policy in the Prison System is the purpose of the project, requested by the Ministry of Health. Nowadays, there is the National Penitentiary System Health Plan (PNSSP) servicing a specific portion of that population, those who had already been through trial and convicted, comprising only the basic health care part, infect contagious diseases and HIV/AIDS. Today, out of 500,000 prisoners, 40% had not been through trial yet and, thus, are not included in the plan. The project intention is that the policy ensures health to all in the prison system, considering even the visitors, employees and all those exposed to the risks existing in penitentiaries, jails, police districts, police departments and others. The proposal will serve as instrument for the federal management to launch the policy. The elements helping the government to take measures will be collected. One of which would be the multiprofessional teams and the health system operation considering the insalubrities present in the places inhabited by those population. Title: Semi attending specialization course on Sanitary Law for members of the Federal Prosecutors’ Office Code: DIREB-002-LIV 12 - Official Number: 25027.000071/2011-04 Period: 12/30/2011 to 12/30/2012 Coordinator: Maria Célia Delduque Nogueira Pires de Sá Partnership: Fiocruz Objectives and results: The course has as general purpose training the federal prosecutors on judicial-sanitary knowledge, so as to develop the expertise for understanding and acting in the contemporary sanitary matters. The education and learning methodology applied in the semi attending course will be through the Virtual Learning Environment (AVA), named Moodle platform, by interactive resources like e-mails, chat and forum. Complementing the distance education and learning methodology, the course includes an attending moment in which the students participate through workshops for preparing a scientific article on sanitary law. The course pedagogic course was developed in 2012, as well as the learning virtual environment design, and the texts, scientific articles and reports. Title: I Specialization course on future intelligence: foresights, strategies and public policies Code: DIREB-003-LIV-12 - Official Number: 25380.004206/2011-73 Period: 12/24/2011 to 12/24/2012 Coordinator: Wagner de Jesus Martins Partnership: Fiocruz Objectives and results: Training of staff for the performance of public policies management and for long term planning with a multidisciplinary perspective of public policies; Foresight and Communicative and Strategic Management. Title: II Health Surveillance specialization course Code: DIREB-004-LIV-12 - Official Number: 25380.004206/2011-73 Period: 12/30/2011 to 12/29/2013 Coordinator: Wagner de Jesus Martins Partnership: Fiocruz Objectives and results: The Latu sensu specialization course in Health Surveillance is different as it is about a course aimed exclusively at the National Health Surveillance Agency (Anvisa) employees and estimates the graduation of up to 70 students in 2 classes. Title: 1st Brazilian Meeting of Foresight and Strategic Planning Code: DIREB-005-LIV-12 e DIREB-006-LIV-12 - Official Number: 011/ANA/2012 Period: 04/20/2012 to 06/30/2012 Coordinator: Wagner de Jesus Martins Partnership: Agência Nacional de Águas e Banco do Nordeste Objectives and results: Meeting the need for making Brazil think about the future. Thinking strategically in the long term is a science that, thus, requires theory, method and tools fitted to a practice in agreement with the objectives of a country supremely inserted in the global scenario, with a socially fair development, environmentally sustainable and humanly committed.

24 Title: VI Sanitary Law specialization course Code: DIREB-007-LIV-12 - Official Number: 25027.000004/2012-62 Period: 08/24/2012 to 06/24/2013 Coordinator: Maria Célia Delduque Nogueira Pires de Sá Partnership: Fiocruz Objectives and results: The course aims at training professionals and/or higher education students for constructing a systematized vision of law and its applicability to the Brazilian sanitary reality. The objective is providing strategic support to the Unified Health System (SUS), trying to contribute for improving the population’s quality of life. The course is offered every year as answer to the anxiety of the professionals related to different federal institutions in the country and assembled from a theoretical and practical approach for knowledge exchanging between the practical reality lived by the students together with the legal ordering. Thirty students graduated in Sanitary Law for acting in SUS and a Fiocruz faculty was consolidated for this specialization. Title: Support to the management of technology, innovations and strategic products for the health system Code: DIREB-008-LIV-12 - Official Number: 25027.00037/2012-11 Period: 09/19/2012 to 03/19/2017 Coordinator: Wagner de Jesus Martins Partnership: Fiocruz Objectives and results: Implementing a technology, innovation and strategic products management for supporting the Industry Complex and Health Innovation department in the management of the development and implementation of new technologies in SUS.

26 Title: Development, state and human capacities: international cooperation project for the Health Human Resources Observatories Network in Latin America (Unasul and other countries) Code: ENSP-002-CAC-12 - Official Number: BR/LOA/1100072.001 Period: 01/09/2012 to 12/10/2012 Coordinator: Valéria Morgana Partnership: Organização Pan-Americana da Saúde (Opas) Objectives and results: Participating and supporting continued thinking, implementation and interaction process of the International Network of Health HR Observatories, in Unasul countries and others that may be selected through studies, meetings, workshops and similar. Events related to the development, state and human capacities and of the organization of other technical bases grounding and promoting the exchange of experiences and the technical intake between the observatories, for the construction of work proposals and efforts articulated planning in the health human resources area. Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-003-LIV-12 - Official Number: 147/2011 Period: 10/03/2011 to 10/03/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Prefeitura Municipal Ribeirão Preto - SP Objectives and results: Training professionals of the Unified Health System (SUS) in the municipality of Ribeirão Preto-SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-004-LIV-12 - Official Number: 210/11 Period: 07/19/2011 to 07/19/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Prefeitura Municipal São João da Boa Vista - SP Objectives and results: Training professionals of the Unified Health System (SUS) in the municipality of São João da Boa Vista SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-005-LIV-12 - Official Number: 048/11 Period: 10/13/2011 to 10/13/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Prefeitura Municipal de Franca - SP Objectives and results: Training professionals of the Unified Health System (SUS) in the municipality of Franca - SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Impacts of violence on health distance course Code: ENSP-006-LIV-12 - Official Number: 25388.000915/2011-18 Period: 12/27/2011 to 02/27/2013 Coordinator: Simone Gonçalves de Assis Partnership: Fiocruz Objectives and results: Providing tools to health service managers and the health professionals caring for the population under violence situation. Title: Professional master’s degree for qualification of the SUS Audit National System and Ombudsman Department Code: ENSP-007-LIV-12 - Official Number: 25388.000936/2011-25 Period: 12/27/2011 to 11/27/2013 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz

27 Objectives and results: Master’s degree course in the field of management and public policies for 30 higher education servers of the SUS General Ombudsman Department (Doges) and of the Audit National Department (Denasus) in the campus of Fiocruz in Brasília. It is included in a permanent education strategy for employees collaborating to the consolidation of the National Systems of Ombudsman and Audit. Title: Basic health care evaluation project in the Basic Health Care Access and Quality Improvement Program - PMAQ-AB Code: ENSP-008-LIV-12 - Official Number: 25388000975/2011-22 Period: 12/23/2011 to 07/30/2013 Coordinator: Márcia Cristina Rodrigues Fausto Partnership: Fiocruz Objectives and results: In loco check of evidences of a set of Basic Health Care quality standards, integral part of the certification process of health teams and management of Basic Health Care. Title: Blood centers management specialization course Code: ENSP-009-LIV-12 - Official Number: 25388.000947/2011-13 Period: 12/23/2011 to 02/23/2013 Coordinator: Maria Infante Partnership: Fiocruz Objectives and results: Training professionals on blood center management and other institutions included in the Blood, Components and Derivates National System (SINASAN), for the development of their specific technical abilities and for them to be able to carry out this function as strategic component for the management and operationalization of their work processes. Title: Training workshops on supply chain management and costs management for blood therapy and hematology services Code: ENSP-010-LIV-12 - Official Number: 25388.000934/2011-36 Period: 12/23/2011 to 12/23/2012 Coordinator: Maria Infante Partnership: Fiocruz Objectives and results: Training professionals acting in the costs management and strategic inputs supply chain management processes for the blood area, so as them to be able to develop their specific technical abilities and to carry out this function as strategic component for the management and operationalization of their work processes. Title: Permanent education program for control in SUS: qualification of Health Municipal Councils Code: ENSP-011-LIV-12 - Official Number: 25388.000916/2011-54 Period: 12/22/2011 to 12/22/2014 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz Objectives and results: The program aims at qualifying the Health Municipal Councils in Brazil through permanent education process. Title: Free attending recycling course for qualification of the SUS Audit National System and Ombudsman Department Code: ENSP-012-LIV-12 - Official Number: 25388.000921/2011-67 Period: 12/23/2011 to 06/23/2013 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz Objectives and results: This project aims at producing didactic material and offering free course intended to the professionals of the SUS Ombudsman Department (Doges) and of the SUS Audit National System (Denasus) acting in the states and municipalities. Title: Qualification project for the Full Health Care Network and its families in violence situation Code: ENSP-013-LIV-12 - Official Number: 25388.000922/2011-10 Period: 12/23/2011 to 12/23/2012 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz

28 Objectives and results: Contributing with critical thinking aimed at the improvement and strengthening of efforts and strategies developed by the Technical Health Area for Children and Mother Breastfeeding of the Ministry of Health (ATSCAM/Dapes/SAS/MS) for children from 0 to 9 years old, considering the seek for setting partnerships with reference institutions to the violence theme in the country. The study is performed through the performance of meetings, field and scientific activities, qualifications of the area professionals, validation of the indicators produced and available. In addition, through critical thinking, it is intended to supporting the preparation of institutional and pedagogic materials on the clinical and psychosocial service of children, adolescents, their families and the aggressors, aiming at consolidating the National Policy for Full Health Care to Children. Title: Distance course on bioethics applied to the scientific researches involving human beings Code: ENSP-014-LIV-12 - Official Number: 25388000935/2011-81 Period: 12/23/2011 to 12/24/2013 Coordinator: Sergio Rego Partnership: Fiocruz Objectives and results:: Development of a training program of human resources on bioethics and ethics in research, based on the strategy of distance education, aiming at qualifying members of the research ethics committees in the country. Title: Characterization of risks related to the exposure to benzene in gasoline stations in the municipality of Rio de Janeiro: a pilot study Code: ENSP-015-LIV-12 - Official Number: 25388.000973/2011-33 Period: 12/21/2011 to 12/21/2012 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Fiocruz Objectives and results: The survey assesses the workers exposure through the main indicators – environmental and biological – of the solvent and will try to learn the risk perception of workers, enabling the construction of a database with information on the exposure to benzene in the municipality, which may serve as assistance to the Worker’s Health Surveillance efforts. Title: Assistance to the training of professionals on full health care to adolescent and youngsters – Network development Code: ENSP-016-LIV-12 - Official Number: 25388.000981/2011-80 Period: 12/27/2011 to 12/27/2013 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz Objectives and results: Assist the efforts of the technical area of youngsters and adolescents health of the Department of Programmatic and Strategic Efforts, of the Health Care Department of the Ministry of Health (ASAJ/ DAPES/SAS/MS) in the management of professionals training on the full health care to adolescents and youngsters, impacting on the implementation and expansion of the development of the BVS/ADOLECBrazil Network. Title: Analysis of the health state of chelonians, birds and marine mammals in Campos basin: microbiology, toxicology, parasitology and food ecology Code: ENSP-017-LIV-12 - Official Number: w/o no. Period: 01/23/2012 to 09/30/2012 Coordinator: Salvatore Siciliano Partnership: CTA - Serviço em Meio Ambiente Ltda. Objectives and results: Definition and systemization of procedures for performance of bacteriologic, parasitological and contamination search for metals in biologic samples of birds and marine mammals found during the activities of the monitoring projects at the Campos basin beaches. Title: National Workshop for Suggestion of Public Policies for Culture and Communication Code: ENSP-018-LIV-12 - Official Number: 25388.000979/2011-19 Period: 12/26/2011 to 12/26/2013 Coordinator: Paulo Duarte de Carvalho Amarante Partnership: Fiocruz Objectives and results:

29 The implementation of the Federal Government guidelines requires efforts promoting the inclusion of several social segments. Those efforts are to be discussed with the very social actors, showing the cultural diversity existing in the country. Those efforts are to reach the society, for a real social change regarding several groups, people and cultures. The goals of the National Workshop for Suggestion of Public Policies for Culture and Communication, held in 2012, were: creating broadcasting, attainment and circulation mechanisms in the culture and communication interface; creating accessibility policies in the culture and communication interface; creating cultural producers training policies in the culture and communication interface for job and income generation; contributing to the citizenship and cultural inclusion of people involved in the cultural diversity segments. Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-019-LIV-12 - Official Number: 146/2011 Period: 11/22/2011 to 11/22/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Local Government of Mauá - SP Objectives and results: Training professionals of the Unified Health System (SUS) in the municipality of Mauá-SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Development of a monitoring and assessment sustainable system for the National Guidelines of Full Health Care to Adolescents and Youngsters Code: ENSP-020-LIV-12 - Official Number: 25388.000937/2011-70 Period: 12/23/2011 to 04/23/2013 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz Objectives and results: The project undertakes, from the study of the adolescent and youngster’s health interfaces with mental health, to produce evidences assisting the activity of the Technical Area of Youngsters and Adolescents Health of the Department of Programmatic Efforts and Strategies of the Health Care Department of the Ministry of Health (ASAJ/DAPES/SAS/MS), relating, overall, to the implementation of the “National Guidelines for Full Health Care to Adolescents and Youngsters”. Title: Scientific training, research and disclosure in the violence and health area Code: ENSP-021-LIV-12 - Official Number: 25388.000976/2011-77 Period: 12/22/2011 to 12/22/2013 Coordinator: Simone Gonçalves de Assis Partnership: Fiocruz Objectives and results: The project aims at giving tools and training health professionals and managers in a course on the area of violence and health. Promoting the thinking and discussion among professionals, health teams and managers nominated by the Health Care Department (SAS). Title: Specialization course on epidemiology for monitoring and responding to emergencies in public health Code: ENSP-022-LIV-12 - Official Number: 25388.000974/2011-88 Period: 12/20/2011 to 02/20/2013 Coordinator: José Fernando de Souza Verani Partnership: Fiocruz Objectives and results: Giving tools to the CIEVS (Strategic Information and Response in Health Surveillance Center) network with grounds, concepts and methods of epidemiology and other related areas of knowledge, allowing the generation of responses to health emergency and injury situations, including those resulting from environmental risks and biosecurity. Title: Food and nutritional education for promoting food and nutritional safety II Code: ENSP-023-LIV-12 - Official Number: 25388.000959/2011-30 Period: 12/27/2011 to 12/27/2013 Coordinator: Denise Cavalcante Barros Partnership: Fiocruz Objectives and results: Promoting a proper and healthy feeding together with daily pleasure, so as to foster the individual’s autonomy and social mobilization; adding value and respecting the cultural and regional specificities of

31 the different social and ethnic groups, under the Food and Nutritional Safety (SAN) and the assurance of the Human Right to Proper Feeding (DHAA) perspectives. Title: Strengthening of RENAST by implementing and assessing the Worker’s Health Surveillance and the use of information for network integration Code: ENSP-024-LIV-12 - Official Number: 25388.000987/2011-57 Period: 12/26/2011 to 12/26/2013 Coordinator: Carlos Minayo Gomes Partnership: Fiocruz Objectives and results: The purpose is to continue the efforts developed by the project “Worker’s Health Surveillance – risk situations in production chains of energy matrices in Brazil”. The emphasis to be given at the moment joins the perspective of formulating a national plan of Worker’s Health Surveillance (VISAT), to be developed by the National Network for Full Health Care to Worker (RENAST), as well as the consolidation of the attributions of that network. Title: Continued training course for social control agents in the Worker’s Health area Code: ENSP-025-LIV-12 - Official Number: 25388.000983/2011-79 Period: 12/20/2011 to 12/21/2013 Coordenador: Carlos Minayo Gomes Partnership: Fiocruz Objectives and results: It represents a new stage in the expansion and consolidation of the advances made in the social control formation process in the Worker’s Health area, being a recycling distance course with some attending moments. Title: Map of the environmental unfairness and health in Brazil Code: ENSP-026-LIV-12 - Official Number: 25388.000989/2011-46 Period: 12/22/2011 to 12/22/2013 Coordinator: Marcelo Firpo Partnership: Fiocruz Objectives and results: This project aims at, from a first mapping, supporting the fight for environmental fairness of several populations and groups affected in their territories by actions and policies based on a development vision considered as not sustainable and prejudicial to health by such populations. In compliance with the environmental fairness and collective health principles, the Map tries to give visibility to the reports presented by communities and organizations through the systematization and socialization of the information available. Title: Training program for members of mother, child and fetal mortality committees in the distance education modality II Code: ENSP-027-LIV-12 - Official Number: 25388.000977/2011-11 Period: 12/20/2011 to 12/20/2012 Coordinator: Marcelo Rasga Moreira Partnership: Fiocruz Objectives and results: It intends to sensitize and train workers, health area managers, members of the mother mortality committees and committees for prevention of child and fetal death, civil society representatives, public defenders and members of the Public Prosecutors’ Office in the combat to mother, child and fetal mortality, for assisting the implementation of reduction strategies. Title: Training program for members of mother, child and fetal mortality committees in the distance education modality II Code: ENSP-028-LIV-12 - Official Number: 25388.000978/2011-66 Period: 12/20/2011 to 12/20/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Fiocruz Objectives and results: It intends to sensitize and train workers, health area managers, members of the mother mortality committees and committees for prevention of child and fetal death, civil society representatives, public defenders and members of the Public Prosecutors’ Office in the combat to mother, child and fetal mortality, for assisting the implementation of reduction strategies.

32 Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-029-LIV-12 - Official Number: 059/2012 Period: 01/31/2012 to 07/31/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Local Government of Presidente Prudente - SP Objectives and results: Training professionals of the Unified Health System (SUS) in the municipality of Presidente Prudente - SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Study and research: job market in health Code: ENSP-030-LIV-12 - Official Number: 25388.000988/2011-00 Period: 12/20/2011 to 12/22/2013 Coordinator: Maria Helena Machado Partnership: Fiocruz Objectives and results: It aims at characterizing the health workforce under the several demographic aspects, analyzing the dynamics and trends of the health job market in Brazil, analyzing the job offer per administrative sphere in health and characterizing the location of health jobs per professional categories over the latest decades as well as writing a book with the results found. Title: Training of health permanent education instructors Code: ENSP-031-LIV-12 - Official Number: w/o no. Period: 01/23/2012 to 12/06/2012 Coordinator: Cristina Figueiredo Partnership: Associação Educacional Nove De Julho Objectives and results: To train professionals of the General Hospital of São Mateus, for expanding the capacity of permanent education processes implementation in the health system, strengthening the National Policy for Training of Health Professionals. Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-032-LIV-12 - Official Number: 022/2011 Period: 09/26/2011 to 09/26/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Local Government of Cruzeiro – SP Objective: Training professionals of the Unified Health System (SUS) in the municipality of Cruzeiro - SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Strengthening of readiness and responses capacity in emergency situations relevant for public health Code: ENSP-033-LIV-12 - Official Number: 25388.000980/2011-35 Period: 12/20/2011 to 12/20/2013 Coordinator: Carlos Machado de Freitas Partnership: Fiocruz Objectives and results: A project created for supporting the action lines of the Health Surveillance Department of the Ministry of Health. This is a national diagnosis aimed at surveying the capacities of preparation and response of the health sector for the natural and technological disasters. It will also serve as one of the assistances to the National Plan for Risk Management and Response to Natural Disasters, specifying the responsibilities of SUS technical areas involved in: emergencies produced by chemicals, radiologic and nuclear emergencies and natural disaster situations. Title: Preparation of didactic material on the Public Policy for the Federal Public Employee Code: ENSP-034-LIV-12 - Official Number: 25388.000991/2011-15 Period: 12/22/2011 to 12/22/2012 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Fiocruz Objectives and results: The public employee, as any worker, is under risk of accidents and work diseases. The absence of

33 health and safety policies, together with the public sector prevention, leads hundreds of employees to licenses due to occupational diseases. The Employee’s Health, Security and Benefits Department is directly responsible for implementing this specific policy of attention to the health of the public employee, which is to govern the efforts related to the work and health relations in the federal public institutions. Title: Mother and child health in prisons Code: ENSP-035-LIV-12 - Official Number: 25388.001004/2011-08 Period: 12/27/2011 to 12/27/2013 Coordinator: Maria do Carmo Leal Partnership: Fiocruz Objectives and results: The project activities contemplate the lives of the pregnant woman, of the mother in prison and her child living in prisons, regarding both the biomedical and the psychological and social aspects. This is about ensuring the mothers in prison and their children the access to prevention and quality assistance similar to that offered to the general population, in addition to enabling, despite the difficulties inherent to the life in prison, favorable conditions for setting affective and social bonds for the psychomotor and social development of the child. This way, the approaches will be pluridisciplinary, with the following four complementing subprojects: health and assistance conditions offered in the pregnancy, labor, birth, puerperium and until the six months after the labor for women in prison and their children living in prisons in Brazil and assessment of the children’s psychomotor development. It will be performed through a survey in all prison units over the metropolitan regions of the state capitals having pregnant women, mothers and their children; list of prisoners and their children, with their families and members of the prison community (guards, other prisoners, penitentiary administration, health professionals, psychologists etc.) constituting the social environment of the prisoners in a confined context, highly hierarchized and frequently violent; modalities and legal grounds of the decisions on the future of the children and their mothers after they leave the prison; and adaptation of the prison environment for having the mothers and their children. Title: Training course for social control agents of the Worker’s Health area in the state of Tocantins Code: ENSP-036-LIV-12 - Official Number: 2009.3055.001282 Period: 12/30/2011 to 08/30/2012 Coordinator: Carlos Minayo Gomez Partnership: State Health Department of Tocantins Objectives and results: Consolidating the Worker’s Health Policy requires the consolidation of the SUS deliberation spaces and of its social control instances. Thus, it is necessary to plan actions contributing to a qualified participation of social leaders, the actors of this process – while advisors and representatives of the existing social movements – in the formulation, implementation, negotiation and assessment of the Health and Work policies. Title: Revision of the STD/AIDS Brazilian Program Code: ENSP-037-LIV-12 - Official Number: 7162548 Period: 04/26/2012 to 11/29/2012 Coordinator: Marly Marques Cruz Partnership: The World Bank Objectives and results: Revising, cataloging and synthesizing the literature over the last two decades on the HIV/AIDS epidemics in Brazil, including unconventional literature. Making the memory on the epidemics and the Brazilian government reaction to it. Performing analytical revision of the HIV/AIDS Brazilian Program from its conception to the moment, covering aspects like therapeutic coverage, alternative treatments and prevention instruments. Gathering and presenting quantitative and qualitative data, including interviews with key actors. Title: III National Qualification Course for SUS Managers (CNQGS III) Code: ENSP-038-LIV-12 - Official Number: 25388.000986/2011-11 Period: 12/22/2011 to 08/22/2012 Coordinator: Valéria Morgana Penzin Goulart Partnership: Fiocruz Objectives and results: It aims at strengthening the knowledge and action bases on the SUS management field, regarding that considered as common to all of its spheres and environments, regardless of complexity, of both the work processes and the managing responsibilities, by means of the educative offer of national scope, contributing for consolidating the SUS.

34 Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-039-LIV-12 - Official Number: CPL Nº 2184/2011 Period: 06/01/2012 to 06/01/2014 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Local Government of Sorocaba - SP Objectives and results: Training professionals of the Unified Health System (SUS) in the municipality of Sorocaba - SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Distance specialization course on Worker’s Health and Human Ecology Code: ENSP-040-LIV-12 - Official Number: 16.220/2011 Period: 12/21/2011 to 12/21/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Local Government of Osasco - SP Objective: Training professionals of the Unified Health System (SUS) in the municipality of Osasco - SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Professional master’s degree on Worker’s Health Surveillance Code: ENSP-041-LIV-12 - Official Number: 250000.045022/2012-71 Period: 05/04/2012 to 05/04/2014 Coordinator: Ana Maria Cheble Bahia Braga Partnership: Ministry of Health - CGSAT/DSAST Objectives and results: The course aims at responding to the training needs of the professionals related to RENAST, found by demands coming in several states and to be organized in national scope, gathering first five or six states of the macro region North and Mid West, under the national policies for worker’s health and permanent education. Title: Virtual course: pharmaceutical services based on the Health Primary Care renewed 2 Code: ENSP-042-CAC-12 - Official Number: BR/LOA/1200083.001 Period: 06/11/2012 to 02/28/2013 Coordinator: Vera Lucia Luiza Partnership: Health Pan American Organization (Opas) Objectives and results: Strengthening the leaders, pharmaceutical services managers in the different health system levels, on the development of pharmaceutical services based on the Health Primary Care (APS) under the perspective of integrating the pharmaceutical assistance and the primary care in the Americas and African countries with Portuguese as official language. Title: Health Economic and Industrial Complex: the evolution and dynamics of Local Production and Innovative Arrangements and Systems in Brazil Code: ENSP-043-CAC-12 - Official Number: BR/LOA/1200049.001 Period: 06/29/2012 to 05/28/2014 Coordinator: Jose Manuel Santos de Varge Maldonado Partnership: Health Pan American Organization (Opas) Objectives and results: The purpose is mapping the health complex by focusing on the Local Productive and Innovative Arrangements and Systems (ASPILs), as way of unveil the local specificities regarding the health services provision and the subsystems of chemical and biotechnological basis and of mechanical, electronic and material basis. This new focus is guided by a perspective considering the social and sanitary demands articulated to the local and regional economic characteristics. Title: Analysis of the process of implementation of the Urgency and Emergency Care Networks (RUE) Code: ENSP-044-CAC-12 - Official Number: BR/LOA/1200044.001 Period: 06/29/2012 to 06/05/2014 Coordinator: Marly Marques da Cruz Partnership: Health Pan American Organization (Opas) Objectives and results: To set technical cooperation for the development of actions for structuring the Urgency and Emergency

35 Care Networks (RUE), in compliance with the national guidelines, for improving the implementation, monitoring and assessment process of the urgency care networks in the country. Title: Distance specialization course on Workerâ&#x20AC;&#x2122;s Health and Human Ecology Code: ENSP-045-LIV-12 - Official Number: 7.828/2011 Period: 08/03/2011 to 08/03/2013 Coordinator: Rita de Cassia Oliveira da Costa Mattos Partnership: Prefeitura Franco da Rocha - SP Objective: Training professionals of the Unified Health System (SUS) in the municipality of Franco da Rocha - SP, for incorporating the relationships among production, environment and health to the health practices, aiming at solving concrete problems, considering work as determiner to the health-disease process and the environment degradation. Title: Professional Appreciation Program (PROVAB) Code: ENSP-046-LIV-12 - Official Number: 25388000445/2012-65 Period: 08/24/2012 to 08/23/2013 Coordinator: Valeria Morgana Partnership: Fiocruz Objectives and results: This project aims at supporting and fostering the reorganization of the health professional training, by implementing the Basic Health Care Professional Appreciation Program (Provab). Title: Development and improvement of methodologies for surveillance and control of the American visceral and tegumentary leishmaniosis at municipal and local levels Code: ENSP-047-LIV-12 - Official Number: 25388.00321/2012-80 Period: 07/16/2012 to 07/16/2013 Coordinator: Paulo Chagastelle Sabroza Partnership: Fiocruz

36 Objectives and results: To advise and support the state and municipal coordinations of the leishmaniosis program on the implementation of the surveillance and control efforts of the local territorial basis. Title: Diagnosis of sanitation at AP-5 in the municipality of Rio de Janeiro Code: ENSP-048-LIV-12 - Official Number: 007/2012 Period: 10/02/2012 to 01/01/2013 Coordinator: Debora Cynamon Kligerman Partnership: FAB ZONA OESTE S.A. Objectives and results: Diagnosis of the sanitation conditions in the districts: Senador Camará, Bangu, Campo Grande, Padre Miguel, Realengo, Magalhães Bastos, Vila Militar, Deodoro, Sulacap, Campos dos Afonsos (1st phase) and in districts: Santa Cruz, Sepetiba, Pedra de Guaratiba, Barra de Guaratiba and Guaratiba (2nd phase). Title: Assessment studies based on the Basic Health Care quality monitoring survey Code: ENSP-049-LIV-12 - Official Number: 25388.000572/2012-64 Period: 10/05/2012 to 10/04/2013 Coordinator: Valeria Morgana Partnership: Fiocruz Objectives and results: Performance of assessment survey, based on the data collection made in the local Basic Health Care network of the states of Rio de Janeiro, Paraná, Espírito Santo, Tocantins, Amazonas, Pernambuco, Alagoas, Roraima and Amapá, in order to assist the decision-making process for the definition to implement the National Program for the Health Basic Units Physical Structure Requalification. Title: Assessment of the RIPSA methodology implementation in the state Code: ENSP-050-CAC-12 - Official Number: BR/LOA/1200106.001 Period: 10/01/2012 to 09/08/2014 Coordinator: Ilara Hammerli Sozzi de Moraes Partnership: Health Pan American Organization - OPAS Objectives and results: Assessing the implementation of the “RIPSA (Health Interagency Information Network) methodology” in five pilot states (Tocantins, Bahia, Mato Grosso do Sul, Minas Gerais and Santa Catarina), as essential stage for its expansion in the other states deciding to adhere to the RIPSA. Title: Specialization course on mental health and psychosocial care 2012 Code: ENSP-051-LIV-12 - Official Number: 25388.000984/2011-13 Period: 09/11/2012 to 09/11/2013 Coordinator: Paulo Duarte de Carvalho Amarante Partnership: Fiocruz Objectives and results: The project aims at providing tools to the professionals acting or to act in the health and mental health network, in agreement with SUS and the Brazilian Psychiatry Reform principles. Title: Specialization course on mental health and psychosocial care Code: ENSP-052-LIV-12 - Official Number: 5325850/2012 Period: 09/27/2012 to 12/30/2013 Coordinator: Paulo Duarte de Carvalho Amarante Partnership: Local Government of Vitoria Objectives and results: Training public health network professionals for acting under the SUS and the Brazilian Psychiatry Reform principles. Title: Access to drugs, trade and foreign agreements for the International Health Leaders Program Code: ENSP-053-LIV-12 - Official Number: BR/CNT/1201480.001 Period: 15/10/2012 to 17/12/2012 Coordinator: Maria Auxiliadora Oliveira Partnership: Health Pan American Organization - OPAS Objectives and results: Developing and implementing the module “Access to Drugs, Trade and Foreign Agreements” within the course for international health leaders, offered by OPAS.

37 Title: The nexus between smoking control and the economic policy Code: ENSP-054-LIV-12 - Official Number: 12159 Period: 07/01/2012 to 12/21/2012 Coordinator: Vera da Costa e Silva Partnership: American Cancer Society Objectives and results: The purpose is identifying and analyzing the strategies applied by the tobacco industry for influencing governments and international economic organisms, in order to understand how the economic policies impact on the execution of tobacco control measures. It intends to help build knowledge on the matter through two great developing countries: Brazil and the Philippines. At first, a planning was developed with the participation of the foreign researchers involved. Right after that, the first data collection was made through interviews with relevant actors for the tobacco control policy in Brazil. Now the team is working on the reference survey for the official literature related to the matter and the second data collection will be started soon, in and outside the country. In the end of the survey, the expectation is to gather a set of reports with comprehensive and proven information on the economic relation and the tobacco control. Besides, a workshop for training the actors on the tobacco control in the country and economic policies formulators is planned, which will enable the discussion on how to integrate the two areas so as them to fit to the public health in a equitable way. Title: Course of strengthening of the Progesus 2012 training component of qualification for SUS managers Code: ENSP-055-LIV-12 - Official Number: 25388.001023/2011-26 Period: 10/22/2012 to 10/22/2013 Coordinator: Neuza Maria Nogueira Moyses Partnership: Fiocruz Objectives and results: It aims at strengthening the implementation of training strategies in the GTES scope; qualifying the work and education management in health; expanding the training efforts on health work and education management and expanding the GTES qualification efforts to the states and municipalities contemplating the existing limited demand. Title: Program for expanding the mouth health resoluteness in Basic Health Care Code: ENSP-057-FIO-12 - Official Number: 25388.000516/2012-20 Period: 11/06/2012 to 11/06/2013 Coordinator: ValĂŠria Morgana Penzin Goulart Partnership: Fiocruz Objectives: Checking in loco the set of quality standards of the work processes of the mouth health Basic Health Care teams, in the National Program for Improving the Access and Quality of Basic Health Care.

39 Title: Improving, qualification and training of student and faculty activities of EPSJV Code: EPSJV-001-LIV-12 - Official Number: 25380.004186/2011-31 Period: 01/05/2012 to 10/06/2012 Coordinator: José Orbílio de Souza Abreu Partnership: Fiocruz Objectives and results: Consolidating the education field in the professional education area, promoting the expansion of the education and research scope in the area, and strengthening the EPSJV share policy. Title: Training course on Environmental Health in the rural settlement territories of the state of Ceará: handling strategy at the health social determiners of country population’s health Code: EPSJV-002-LIV-12 - Official Number: 25380.004220/2011-77 Period: 02/7/2012 to 08/07/2013 Coordinator: Gladys Myashiro Myashiro and Andre Campos Burigo Partnership: Fiocruz Objectives and results: It aims at qualifying 50 rural workers members of the settlements or acting in the land reform for promoting and managing essential knowledge, incorporating technical and political knowledge as well as ethic principles, with emphasis on the environmental health problems in rural settlements. Title: Training course on Environmental Health in the rural settlement territories of the state of Paraná: handling strategy at the health social determiners of country population’s health Code: EPSJV-003-LIV-12 - Official Number: 25380.004221/2011-11 Period: 01/05/2012 to 07/05/2013 Coordinator: Gladys Myashiro Myashiro e Andre Campos Burigo Partnership: Fiocruz Objectives and results: Qualifying 50 rural workers members of the settlements or acting in the land reform for promoting and managing essential knowledge, incorporating technical and political knowledge, with emphasis on the environmental health problems in rural settlements. Title: Support to education, research and improvement of technical and professional training on health for the high school level Code: EPSJV-004-LIV-12 - Official Number: 25380.002103/2012-50 Period: 09/17/2012 to 09/17/2013 Coordinator: José Orbílio de Souza Abreu e Marco Antônio Carvalho Santos Partnership: Fiocruz Objectives and results: Ensuring the access to the professional education and research on health, as well as the expansion of professional training efforts developed by EPSJV in all levels. Title: National Program for Integration of Professional Education to the Basic Education in the Youngsters and Adults Education (PROEJA) Modality Code: EPSJV-005-LIV-12 - Official Number: 25380.001786/2012-28 Period: 10/10/2012 to 11/01/2012 Coordinator: Marco Antônio Carvalho Santos Partnership: Fiocruz Objectives and results: Strengthening the education field in the technical instruction area for health, science and technology, in addition to promoting the expansion of the health professional education scope.

41 Title: Technology transfer to the Mozambican Drug Society Code: FAR-001-LIV-12 - Official Number: 25387.000703/2011-32 Period: 12/27/2011 to 06/27/2014 Coordinator: Maria Amália do Nascimento Monteiro Partnership: Fiocruz Objectives and results: Technology transfer to the Mozambican Drug Society with the implementation of the antiretroviral factory and other drugs of Mozambique Title: Clinical Research Code: FAR-002-LIV-12 - Official Number: 25387.000655/2011-02 Period: 12/28/2011 to 06/28/2013 Coordinator: Tereza Cristina dos Santos Partnership: Fiocruz Objectives and results: The drugs made by Farmanguinhos aim at meeting the demands of the Health Ministry and the regulation in force of the National Health Surveillance Agency, and the project purpose is to support the unit implementation of actions for making strategic drugs for health, by developing the program of Pharmaceuticals, Drugs and Phytotherapeutics Production and other activities ensuring the achievement of the following goals: supporting strategic efforts for performance of bioavailability studies regarding the products; monitoring results of the bioavailability studies; coordinating strategic efforts for requesting the products registration; purchasing of consumables; contracting of third party services for performing three dissolution profile analyses, two equivalences, two bioequivalences and two clinical tests. Title: Biodiversity and Health itinerant exhibition Code: FAR-003-FEX-12 - Official Number: sem nº Period: 10/18/2012 to 08/18/2013 Coordinator: Maria Amália Nascimento Monteiro Partnership: JAM Engenharia, Nortec Quimica, Globe Química S/A, Relthy Laboratórios LTDA Objectives and results: The purpose is strengthening the performance of education and health activities aimed at the school community of Cidade de Deus. The idea is emphasizing the relevance of conserving the Brazilian ecosystems biodiversity to the public health and the production of pharmaceuticals. This emphasis will be given through exhibitions on the theme. With estimated duration of ten months, the project is divided in three phases: study and development of the exhibition theme content; selection, contracting and training of monitors and coordinators of the exhibition; and planning, logistics, disclosure and execution of the exhibitions on biodiversity and health. The exhibition will have two main themes. The first is the emergency of infect contagious diseases, putting in evidence the environmental unbalance. The other emphasizes the importance of preserving the biodiversity, specially the plants, for the production of drugs.

44 Title: National Health Survey – active search survey for deaths in the municipalities selected and development of models for estimating mortality indicators in areas with poor information Code: ICICT-001-LIV-12 - Official Number: 25380.004164/2011-71 Period: 30/12/2011 to 30/12/2012 Coordinator: Celia Landmann Szwarcwald Partnership: Fiocruz Objective: Planning the National Health Survey (PNS) with development and/or improvement of tools for the assessment of the national health system as well as estimating the coverage of the Information Systems on Mortality (SIM) of the Ministry of Health, and estimating the child mortality per Brazilian municipality. Title: Support to the implementation of methodology to train health professionals for SUS Code: ICICT-002-LIV-12 - Official Number: 25380.004259/2011-94 Period: 01/01/2012 to 01/04/2013 Coordinator: Maria Cristina Soares Guimarães Partnership: Fiocruz Objectives and results: Fostering discussions regarding the integration among health information, education and work, joining managers, workers and training institutions under the perspective of reorganization of education practices, production of information and care, contributing to the consolidation and qualification of the basic health care and the constitution of full care networks. Title: Study and research on the health of aged people – Aged people Health and Quality of Life Monitoring System Code: ICICT-003-LIV-12 - Official Number: 25380.004165/2011-15 Period: 01/04/2012 to 04/07/2013 Coordinator: Dalia Elena Romero Montilla Partnership: Fiocruz Objectives and results:: Qualifying state coordinators of aged people health policies of SUS for using the Aged people Health and Quality of Life Monitoring System (Monitor-Idoso). Title: Production, distribution and display of documentaries on workers’ health and environment in the grains agribusiness sector of the state of Mato Grosso - SES/MT Code: ICICT-004-LIV-12 - Official Number: 055/2011/SES/MT Period: 10/14/2011 to 02/09/2013 Coordinator: Sergio Luiz Da Silva Brito Partnership: Fundo Estadual de Saúde Mato Grosso Objectives and results: One of the objectives is to promote the dissemination of knowledge by producing two documentaries with 22 minutes each. Besides, it aims at promoting the distribution and display of the documentaries for TV channels included in the network under agreement with Fiocruz, as UTV - Rio de Janeiro, Canal Saúde, TV OI, Canal Minas Saúde, among others. Title: 7th edition of the specialization course on scientific and technologic information on health and support to education, research and extension activities developed by Escola GHC Code: ICICT-005-LIV-12 - Official Number: 1779/11 Period: 04/11/2012 a 04/11/2013 Coordinator: Maria Cristina Soares Guimarães Objectives and results: Continuing the works developed in the partnership between Grupo Hospitalar Conceição and Fiocruz, with the 7th Edition of the course and the production of three publications with scientific and technologic information on health. Title: Support to the realization of the XIII ENANCIB – National Meeting of Research on Information Science Code: ICICT-006-LIV-12 - Official Number: 25380.001150/2012-86 Period: 06/18/2012 to 11/07/2012 Coordinator: Maria Cristina Soares Guimaraes Partnership: Fiocruz Objectives and results: Occurred in Rio de Janeiro, from 28 to 31/10, with the theme “The society in network for innovation and human development”. Over the four days of the event, 708 researchers watched the 315 presentations occurred in the 11 work groups (GTs). Enancib is the main research event on Information Science in

45 Brazil. The meetings are promoted every year by the National Association of Researches and Graduation on Information Science (Ancib) for presentation and discussion of the scientific research in the Brazilian Information Science area, gathering the set of national researchers and graduation programs on the area. The purpose is fostering the thinking on the role of network information in the society, especially regarding innovation for a sustainable human development. Title: Program for Induction to Technological Research and Development of ICICT (PIPDT) Code: ICICT-007-LIV-12 - Official Number: 25380.001201/2012-70 Period: 07/25/2012 to 07/25/2014 Coordinator: Christovam Barcelos Partnership: Fiocruz Objectives and results: It aims at strengthening and operationalizing the PIPDT, whose objective is inducing and encouraging the development of scientific and technological researches regarding the interdisciplinary field of information and health communication.

47 Title: Performance of the 2nd phase of preliminary studies for the feasibility of the national health cut for aged people Code: ICPQRR-001-LIV-12 - Official Number: 25381000184/2011-62 Period: 11/30/2011 to 12/30/2012 Coordinator: Maria Fernanda Lima Costa Partnership: Fiocruz Objectives and results: Performance of longitudinal studies on the aged people’s health and its determiners (in addition to the social and economic aspects), in national samples representing people with 50 years or more. This is a great sample study, with about 15,000 participants each. The proposal is a feasibility study for implementing the Longitudinal Health Study for Aged People in Brazil. Title: Complementation of the Brazilian Planorbidic Letter in the states of Paraná, Minas Gerais, Bahia, Pernambuco and Rio Grande do Norte Code: ICPQRR-002-LIV-12 - Official Number: 25381.000253/2011-38 Period: 01/10/2012 to 01/10/2014 Coordinator: Omar dos Santos Carvalho Partnership: Fiocruz Objectives and results: The selection of the five states for the complementation of the Planorbidic Letter is due to the following: need for knowing the intermediary host planorbidic fauna of esquistossomiasis in the municipalities still not researched; and, as they are historically endemic states and with the incoming of new foci. The study aims at making three aspects explicit: the geographic distribution of Biomphalaria glabrata, the geographic distribution of Biomphalaria straminea and the geographic distribution of Biomphalaria tenagophila. In the state of Paraná, 62 municipalities were worked out of the 89 expected. There are 27 municipalities left. In the state of Minas Gerais, 66 municipalities were worked out of the 69 first expected, leaving three municipalities that are to be surveyed after the rainy period. In the state of Pernambuco, a training course was given to 19 professionals on mollusks catchment and packaging techniques. Out of the 19 municipalities first expected in the project, 14 were worked, leaving five municipalities to be worked after the dry period. In the state of Bahia, out of the 76 municipalities first expected in the project, 2 were worked, leaving 74 municipalities. Finally, in the state of Rio Grande do Norte, out of the 95 municipalities first expected in the project, 5 were worked, leaving 90 municipalities. Title: Monitoring of the triatomine insects susceptibility/resistance to insecticides Code: ICPQRR-003-FIO-12 - Official Number: 25381.000135/2012-19 Period: 11/30/2012 to 11/30/2014 Coordinator: Lileia Gonçalves Diotaiuti Partnership: Fiocruz Objectives and results: It aims at implementing a network made of SUS laboratories for monitoring the susceptibility/resistance of triatomine insects to insecticides, involving the participation in the National Program for Controlling Chagas Disease of the Health Surveillance Department (SVS), regional laboratories of the General Laboratories Coordination (CGLAB/SVS), of the State Managements of the Program for Controlling Chagas Disease and of the Laboratory for Triatomine Insects References and Epidemiology of Chagas Disease/Fiocruz Minas.

49 Title: Strengthening and dissemination of the National Policy for Full Health Care to Men (PNAISH) Code: IFF-001-LIV-12 - Official Number: 25384.000633/2011-42 Period: 12/20/2011 to 12/20/2012 Coordinator: Romeu Gomes Partnership: Fiocruz Objectives and results: The National Policy for Full Health Care to Men (PNAISH) was instituted by the Ministry of Health for promoting the improvement of the health conditions of the male population in Brazil, contributing, effectively, to reduce the morbidity and mortality through the rational combat to the risk factors and upon the facilitation to the access, to the actions and to the services of full health care. The PNAISH institution came after several discussions, involving different social actors, institutions and civil entities. The product of those discussions was submitted to public reference for enabling greater participation of the society in general. The implementation of that policy, among other aspects, involves the changes of paradigms for the promotion, together with male segments, of the care with their health and with the health of their families. This demands several efforts ranging from organizing health services, including training professionals, until the educational efforts with the male segments. Those efforts, in turn, to be successful, need support mechanisms. From this perspective, the development of this broad project of national character is justified for strengthening and disseminating the PNAISH precepts. The following workshops were offered: Planning of the Primary Man Health Care Book, construction of matrix with indicators for assessing PNAISH and workshop with state and municipal managers for presenting and validating indicators for assessing PNAISH’s efforts. Title: Human Milk Bank Network – Phase IV Code: IFF-002-LIV-12 - Official Number: 25384.000637/2011-21 Period: 12/20/2011 to 12/20/2012 Coordinator: Paulo Ricardo da Silva Maia Partnership: Fiocruz Objectives and results: It aims at modernizing, expanding and consolidating the National Human Milk Bank Network, phase IV – education, information and quality monitoring. The REDEBLH growth results from the successful articulation between health policy, interinstitutional integration and service to the society demands for improved quality of life. Thus, REDEBLH takes a strategic role, due to the results of services and products, with the confluence of coordinated efforts giving priority to qualification and participative management, ensuring, this way, the offer of a product meeting the quality requirements in the mother-child health area. This conjecture indicates the possibility of viewing the REDEBLH future, through a double movement that can be characterized as expansion and consolidation. Regarding expansion, the need for capillarizing the activities to promote the mother breastfeeding and for implementing new Human Milk Banks (BLH) was found. Regarding consolidation, the priorities are the setting of the institutional milestone, with structuring and regulatory efforts to the modernization of the technological park of the units under operation, to the permanent education of their human resources, and to the certification of all BLH for the qualification in the Ibero-American Human Milk Bank Program. Among the actions developed by the project for that purpose are: creation of an Information Management Integrated System SIGI-REDEBLH, accreditation of the BLH in the Ibero-American Program, modernization of the Technological Park, holding of macro regional meetings coordinating BLH and other 14 events. Title: Contributions of the Healthy Little Brazilians to the formulation and implementation of the Full Policy for Children’s Health Code: IFF-003-LIV-12 - Official Number: 25384.000607/2011-14 Period: 12/30/2011 to 12/30/2012 Coordinator: Hamilton Avila Partnership: Fiocruz Objectives and results: Meeting the requests of the National Committee for Health Social Determiners (CNDSS) and of the World Health Organization (WHO), the Ministry of Health (MS) prepared a strategy aimed at combating the iniquities in women’s and 0 to 6 year old children’s health. This life stage, designed as first childhood, considers the importance of the primitive emotional development as basis of the healthy growth potential of the little Brazilian citizen. The initiative named “Contributions of the Strategy Healthy Little Brazilians (EBBS) for the formulation and implementation of the full policy for children’s health”, in the scope of the Unified Health System (SUS), has its activities aimed at the process of formation and intervention of their main actors and for the beginning of a longitudinal assessment of the formulation and implementation of the Full Policy for Children’s Health. In this sense, the project aims at preparing the political and technical guidelines for the full 0 to 10 year old children’s health care and supporting its implementation in the states and municipalities as well as promoting formation and intervention processes, as the formation

50 processes guidelines are grounded on the principle of it being indivisible from the change processes. That is, forming is intervening through the knowledge accrued. For such, the following actions were performed: training course on pediatric urgencies and emergencies for 581 professionals of SUS; revision of the Newly Born Manual, especially the chapters dedicated to the prevention to infection, precocious sepsis and common procedures in neonatology; creation of a work group for organizing the follow up meetings of those who left the neonatal ITU, including premature, seriously anoxic babies and other co-morbidities needing monitoring, including children with intrauterine exposure to alcohol and drugs; writing of the Altasa Respiratory Infection Prevention Project; participation in the formulation of the Neonatal Guidelines in the Group of Specialists of Cegonha Network; among others. Title: The interfamily violence and the disabled children and adolescents: a study based on the application of the Parent-Child Conflict Tactics Scales (CTSPC) Code: IFF-004-LIV-12 - Official Number: 25384.000682/2011-85 Period: 12/30/2011 to 12/30/2013 Coordinator: Olga Maria Bastos Partnership: Fiocruz Objectives and results: The study has as purpose measuring physical, psychological ill-treatment and negligence, as well as nonviolent strategies of education in the parent-child/adolescent with any disability. The support network to those children and adolescents in the city of Rio de Janeiro and surrounding municipalities will be mapped. The final goal is preparing a catalog for service network to disabled children and adolescents with data, referent information and measures to be taken. This project follows the research “Disabled Children and Adolescents under Violence Situation in the Metropolitan Region of the State of Rio de Janeiro – an analysis of the ill-treatments notifications”, also performed by IFF, analyzing the notifications on ill-treatment and/or violation of children’s and adolescents’ rights in eight guardian councils of the Metropolitan Region of Rio de Janeiro (Ramos, Campos Grande, Duque de Caxias, São Gonçalo, Nova Iguaçu, Belford Roxo, São João de Meriti and Niterói). The survey found the several kinds of violence suffered, measuring that 42% of children and adolescents have their basic rights violated. Title: Implementation of the National Policy for Humanization (PNH) in the health care networks of SUS Code: IFF-005-LIV-12 - Official Number: 25384.000669/2011-32 Period: 12/30/2011 to 06/30/2013 Coordinator: Hamilton Ávila Partnership: Fiocruz Objectives and results: Qualifying the health care and management in the networks and its several attention topics and strategies, including PNH institutional supporters training and assessing monitoring process for the implementation of those networks. Title: Badalando a Cidadania – contributions of Badalando a Cidadania to the promotion of health of the adolescents participating in the project, after three years of activities Code: IFF-006-LIV-12 - Official Number: 25384.000718/2011-21 Period: 12/30/2011 to 12/30/2013 Coordinator: Olga Maria Bastos Partnership: Fiocruz Objectives and results: Promoting the assurance of basic rights to the child and juvenile population. The project, comprising a population of 200 adolescents (10 to 19 years) and their families, made an association to the Grêmio Recreativo Badalo de Santa Teresa and performed several artistic and sports activities, health workshops, as well as research for learning some aspects relating to the life of that population. Title: Consolidation and strengthening of the National Policy for Mother Breastfeeding and Full Child’s Health Care Code: IFF-007-LIV-12 - Official Number: 25384.000634/2011-97 Period: 12/30/2011 to 12/30/2012 Coordinator: Paulo Ricardo da Silva Maia Partnership: Fiocruz Objectives and results: It aims at promoting, protecting and supporting the mother breastfeeding over the country, in the context of the objectives and priorities of the Cegonha Network and Healthy Little Brazilians Strategy (EBBS), and developing efforts aimed at a Full Child’s Health Care, together with the federative, state and municipal entities, and under the Cegonha Network and EBBS principles. The project main goals are: consolidating and strengthening the National Policy for Mother Breastfeeding and Full Child’s

51 Health Care, by means of supporters and supervisors acting in the states; strengthening, monitoring and assessing the Amamenta Brasil Network and the Initiative Hospital Amigo da Criança (IHAC); protecting and supporting breastfeeding for two years or more and the exclusive mother breastfeeding in the first 6 months of life among the working mothers; teaching, communicating and mobilizing actors and partners in the promotion, protection and support actions to mother breastfeeding. Over 2012, the project has promoted and supported 64 events (courses, lectures, meetings and workshops) in several cities of Brazil. Title: Sexuality in the adolescence: from individual experience to social relations and the specificities of pregnancy in adolescents as assistance to the implementation of the Cegonha Network in the municipality of Rio de Janeiro Código: IFF-008-LIV-12 - Official Number: 25384.000731/2011-80 Period: 12/30/2011 to 12/30/2013 Coordinator: Olga Maria Bastos Partnership: Fiocruz Objectives and results: Weekly thinking groups were gathered with pregnant adolescents and mothers attending to the IFF for appointment in the gynecology clinic and of adolescents. Seventy-six children, children under 1 year old of adolescents who had prenatal monitoring in the IFF were serviced; provision of gynecologic service to 71 adolescents; and 68 interviews with adolescents users of the prenatal, gynecology and pediatric clinics, for knowing the families’ social history. Title: On the Radio Waves: violence prevention against children and adolescents Código: IFF-009-LIV-12 - Official Number: 25384.000713/2011-06 Period: 12/30/2011 to 12/30/2012 Coordinator: Mariana Simões Barros Partnership: Fiocruz Objectives and results: The project aims at increasing the social actors operating in the community, school and commercial radios, in order to expand the activity and sensitization of population regarding preventing violence, notifying cases and promoting the rights of children and adolescents. The goals are: identifying radio networks of the states of the Northeast and Legal Amazon, in addition to Rio de Janeiro, Florianópolis and Campo Grande and sensitizing the broadcasters acting in those radios; building the methodological content to be used in the sensitization of the community, school and commercial radio professionals in those places; converging the broadcasters participating in the project and the partners to the presentation of the proposal/methodological results and agreement on the commitment to promote the assurance of the children’s and adolescents’ rights; promoting the power of the communication means in the prevention of violence against children and adolescents and the peace culture, by optimizing the community talents in the production of thematic radio plays; creating and producing media products (vignettes, spots, raps, parodies, stories) on the theme to be used in the communication means; and constructing data base in FormSUS with the profile of the professionals qualified and tutors for monitoring and assessment, network formation and support to the management. Altogether, 100 broadcasters went through the sensitization process and 20 radio plays were produced together with 1,000 mp3 media edited.

53 Title: Study on new Inflammation Resolution Mechanisms (TIMER) Code: IOC-001-LIV-12 - Official Number: 281608 Period: 01/01/2012 to 01/01/2016 Coordinator: Marco Aurélio Martins Partnership: European Union-Fondazione Humanitas Objectives and results: Development of innovative therapeutic strategies for chronic and self-immune inflammatory diseases by identifying and validating new molecules involved in the inflammation resolution. Title: Assessment of problems for the Aedes Aegypti surveillance - Phase II Code: IOC-002-LIV-12 - Official Number: 25030.000480/2011-43 Period: 12/16/2011 to 12/16/2013 Coordinator: Denise Valle Partnership: Fiocruz Objectives and results: Assessing the use of different types of problems for catching Aedes Aegypti, making a panel representing the temporal changes and of resistance profile due to the field control efforts and developing an application for managing the resistance monitoring. Title: Environment surveillance in rickettsiosis Code: IOC-003-LIV-12 - Official Number: 25030.000440/2011-00 Period: 01/12/2012 to 01/12/2014 Coordinator: Gilberto Salles Gazeta Parceria: Fiocruz Objectives and results: Training, qualification and habilitation of professionals for investigating the environment in rickettsiosis. Title: XVII Laveran & Deane Seminar on Malaria Code: IOC-004-LIV-12 - Official Number: w/o no. Period: 03/01/2012 a 03/01/2013 Coordinator: Cláudio Tadeu Daniel Partnership: Construtora Norberto Odebrecht SA Objectives and results: The event aims at gathering researchers from IOC and other national and international institutions to discuss on malariology projects and their results, promoting knowledge exchange and strengthening the technical cooperation and partnerships in projects development. Title: Field tests with synthetic sexual pheromone to reduce the transmission of visceral leishmaniosis by Lutzomyia longipalpis Code: IOC-005-LIV-12 - Official Number: w/o no. Period: 07/02/2012 to 06/27/2014 Coordinator: Reginaldo Peçanha Brazil Partnership: University of Keele (Welcome Trust) Objectives and results: The visceral leishmaniosis (LV) is a serious disease and may be mortal if not diagnosed in time. In Brazil, it is transmitted by the bite of females of small insects infected by the protozoan Leishmania infatum chagasi, being the main vector species the Lutzomyia longipalpis. The female insect infection occurs at the moment when it feeds itself from the blood of infected host vertebrate animals. The success of such feeding is given to the strong attraction resulting from the combination of the animal smell and the sexual pheromone made by flebotomineous males, which are attracted by them. In other researches performed, it was possible to synthesize and make large quantities of the pheromone in laboratory. When it is placed together with the host, for example, in an animal’s shelter, the substance plays the male action for attracting the females to blood feeding, powered by the smell emitted by the animals attracting the insects. Thus, the utilization of residual action insecticides is studied for making them more efficient to fight those insects, as there would be more female attraction to the place where the pheromone would be exposed, serving both to attract and kill great quantities of insects of both genders. In this study, the intention is to test, in field, the “attract and kill” strategy, aiming at reducing the dog infection and the density of the Lutzomyia longipalpis population, reducing also the LV in human beings. Title: Organization of technical and scientific events coordinated by the IOC and/or in partnership with other institutions related to the information, health education communication, science, and technology areas Code: IOC-006-LIV-12 - Official Number: 25030.000639/2012-19

54 Period: 08/02/2012 to 08/02/2013 Coordinator: Helene Santos Barbosa Partnership: Fiocruz Objectives and results: The Oswaldo Cruz Institute (IOC), a technical and scientific unit of Fiocruz, relies on six Stricto sensu graduation programs and receives, every year, a relevant quantity of students attending to master’s, doctor’s, specialization, recycling and technical level specialization degree courses. In addition, the IOC has an extensive tradition in qualifying human resources on the biomedical area. This process is managed by the Education, Information and Communication Vice-Directorate and is grounded on the investment in the IOC formal courses, on the organization of weekly study centers and on the promotion of scientific events (seminars, symposiums, conferences) by the different research laboratories and efforts promoted by the unit’s Directorate. The operational and logistic planning is organized by the IOC Events Center. The planning and execution of communication are, in turn, under the responsibility of the IOC Journalism and Communication Service (SEJOR/IOC). The project goals already met are: fostering of debates on scientific projects and their results; strengthening of technical cooperation and partnerships in the projects development; promoting interaction among students, researchers, professors; encouraging of more participation in the definition of the graduation policy; promoting the exchange between the faculty and advisors in the construction of graduation guidelines in the light of the Brazilian policy for the area; fostering the formation of students in specific areas of knowledge; consolidation of regular forums in the human resources formation area; and disclosure of scientific research developed by the IOC education areas. Title: Implementation of the Institutional Quality Program Code: IOC-007-LIV-12 - Official Number: 25030.000601/2012-38 Period: 07/23/2012 to 07/23/2013 Coordinator: Elizabeth Ferreira Rangel Partnership: Fiocruz Objectives and results: To develop processes ensuring the GesPublica guidelines in the IOC management activities through fitting processes and supporting the legislation in force, adopt environmental sustainability policies and implement the quality system standards. Title: Workshop sobre quimioprofilaxia em malária Code: IOC-008-CAC-12 - Official Number: w/o no. Period: 09/23/2012 to 09/27/2012 Coordinator: Claudio Tadeu Ribeiro Partnership: Health Pan American Organization (OPAS) Objectives and results: This workshop is included in the XVIII International Congress of Tropical Medicine, LXVIII Congress of the Brazilian Society of Tropical Medicine, XXVII and XVI Annual Meetings of Applied Research on Chagas Disease and Leishmaniosis and the III Latin American Congress of Travel Medicine, discussing the use or not of chemoprophylaxis for malaria in Brazil. Title: XVIII Congress of Tropical Medicine and Malaria - Amazonas Code: IOC-009-LIV-12 - Official Number: 14062/2012 Period: 05/29/2012 to 11/29/2012 Coordinator: Claudio Tadeu Ribeiro Partnership: State Health Department SUSAM Objectives and results: Support to the event in Brazil, offering the opportunity to discuss the main problems of tropical medicine in Latin America and as major challenge to health in the 21st Century. Title: Waters Agent Program for participative monitoring and integrated assessment of the quality of river waters in the hydrographic basin of Araruama and Saquarema lagoons and the rivers São João and Una Code: IOC-010-LIV-12 - Official Number: sem nº Period: 09/18/2012 to 09/18/2014 Coordinator: Daniel Forsin Buss Partnership: Prolagos S/A, Concessionária Águas de Juturnaíba S/A Objectives and results: To appoint strategies for solving problems as the need for protecting aquatic life and involving the community in the decision-making processes on waters, by using biologic monitoring to assess the waters’ quality. This way, the intention is to ensure the balance of ecosystems and the setting of methods that may be applied by the communities.

55 Title: Updating of the climate change vulnerability map Code: IOC-011-LIV-12 - Official Number: 25030.000702/2012-17 Period: 09/06/2012 to 03/06/2013 Coordinator: Martha Macedo de Lima Barata Partnership: Fiocruz Objectives and results: Updating of the vulnerability map of the population in the state of Rio de Janeiro to the impacts of the climate changes in the social, health and environment areas, considering the results of the Censo 2010. Other objective is presenting the project results to the academic, government communities and other interested parties. Title: TARKINAID – new therapeutic approaches to chronic inflammatory and self-immune diseases Code: IOC-012-LIV-12 - Official Number: 282095 Period: 01/01/2012 to 01/01/2016 Coordinator: Hugo Caire de Castro Faria Neto Partnership: Semmelweis University Comunidade Europeia Objectives and results: Development of therapeutic strategies for treating chronic and self-immune inflammatory diseases. Title: Laboratory micro network sustainability for genotyping of HIV-1 for new drugs (Renageno) in patients with multiple therapeutic failures or patients multiresistant to antiretroviral therapy (TARV) Code: IOC-013-LIV-12 - Official Number: 25030.000600/2012-93 Period: 10/04/2012 to 10/04/2013 Coordinator: Mariza Gonçalves Morgado Partnership: Fiocruz Objectives and results: Implementation of a national micro network with six laboratories able to execute the genotyping exam in house for the new drugs applied in the redemption of multiresistant patients. Title: Green biocide – synthesis and scaling of non-oxidizing molecules for controlling of biophenomena in the oil industry according to safety, environment and health guidelines Code: IOC-014-LIV-12 - Official Number: 0050.0079655.12.9 Period: 11/23/2012 to 05/22/2015 Coordinator: Tania Cremonini de A. Jorge Partnership: Petróleo Brasileiro SA Objectives and results: Organic synthesis of non-oxidizing molecules and testing of the efficacy of the respective products, in isolation, through the combinations of assets or upon changes to the base-molecule, against specific bacterial targets of the oil industry, interesting to the worker’s and the environment safety and health areas. Title: Formation of special classes for development in doctor’s degree of the faculty of the Federal Institute of Education, Science and Technology of Acre - IFAC Code: IOC-015-FIO-12 - Official Number: 25030.001004/2012-21 Period: 11/27/2012 to 11/27/2016 Coordinator: Paulo Sergio D’Andrea Partnership: Fiocruz Objective: This project was created due to the urgent need of doctor’s degree level formation in the staff acting in the National System of Education in the Amazon, more specifically in the Federal Institute of Education, Science and Technology of Acre.

57 Title: A phase III, international, double-blind randomized, double-masked study for assessing the efficacy and the safety of 300 mg or 600 mg of intravenal Zanamivir, twice a day, compared to 75mg of oral Oseltamivir, twice a day, in the treatment of adults and adolescents hospitalized with flu Code: IPEC-001-LIV-12 - Official Number: w/o no. Period: 05/26/2011 to 12/31/2013 Coordinator: Patricia Brasil Partnership: Glaxosmithkline Brasil LTDA Objectives and results: Open single arm study, selected to reach the primary objective of providing the normative agencies data on the safety of Zanamivir IV, immediately and real time if required, and, thus, gathering comprehensive data on the clinic efficacy, antiviral activity and safety regarding the oral Oseltamivir. Title: Chemoprophylaxis for HIV prevention in men (IPREX OLE) Code: IPEC-002-LIV-12 - Official Number: FCO 0080.0155/854 Period: 10/01/2011 to 07/31/2013 Coordinator: Valdilea Veloso Partnership: Family Health International National Institute of Health (FHI) Objectives and results: Participation in the study on IPREX OLE, which is an extension of the IPREX study, with the purpose of giving further information on safety and behavior during the long term utilization of PrEP. Title: Caribbean, Central America and South America work net (CCASAnet) on HIV epidemiology Code: IPEC-003-LIV-12 - Official Number: VUMC38833 Period: 10/01/2011 to 05/31/2013 Coordinator: Beatriz Grinsztejn Partnership: Vanderbil University Medical Center Objectives and results: Participation in the collaborative study and observation network of Caribbean, Central America and South America (CCASAnet) by researchers with experience in HIV care for assessing the similarities and differences in the HIV pediatric care standards and the diseases closures in the regions with technology and clinical and epidemiologic data sharing. Title: The South American Prevention of HIV Research Training Program (SAPHIR) Code: IPEC-004-LIV-12 - Official Number: 1568 G PA774 Period: 1/8/2011 to 31/5/2013 Coordinator: Valdilea Gonçalves Veloso Partnership: National Institute of Health (NIH) and University of California Objectives and results: Covering the deficit in the training system of the area of research on HIV prevention in international environment. Title: Preventive education on STD/HIV/AIDS in the state of Rio de Janeiro Code: IPEC-005-LIV-12 - Official Number: ED00714/2012 AS-1613/2012 Period: 05/21/2012 to 01/31/2013 Coordinator: Valdilea Gonçalves Veloso Partnership: United Nations Educational, Scientific and Cultural Organization - Unesco Objectives and results: Training health professionals from the I and II metropolitan regions of the state of Rio de Janeiro on actions for preventing and caring for syphilis and HIV. Title: Pharmacological analysis of strengthened Lopinavir/Ritonavir together with Rifampin in patients infected by HIV with tuberculosis Code: IPEC-006-LIV-12 - Official Number: w/o no. Period: 09/21/2012 to 12/07/2013 Coordinator: Valéria Cavalcante Rolla Partnership: University of Miami Objectives and results: Assessment of the plasmatic concentrations and toxicity of the association of Llopinavir 400 mg and Ritonavir 400 mg for treating patients with tuberculosis and AIDS using Rifampicina.

59 Title: Implementation of communication and record center for events in the public health area Code: PRES-001-LIV-12 - Official Number: 25380.004146/2011-99 Period: 12/15/2011 to 12/15/2013 Coordinator: Marcia Correa e Castro Partnership: Fiocruz Objectives and results: Structuring of TV news responsible for covering the events, themes and debates of the health sector broadcasted in Canal Saúde. Title: V Sanitary Law specialization course Code: PRES-002-LIV-12 - Official Number: 25380.004163/2011-26 Period: 12/22/2011 to 06/22/2012 Coordinator: Maria Célia Delduque Partnership: Fiocruz Objectives and results: Development of attending Sanitary Law courses to provide the students judicial-sanitary knowledge, so as to develop the expertise for understanding and acting in the contemporary sanitary matters. Title: Social technologies core for equanimous, territorialized and sustainable development in Manguinhos Code: PRES-003-LIV-12 - Official Number: 25380.003704/2011-07 Period: 12/26/2011 to 12/26/2014 Coordinator: Jose Leonidio Madureira Souza Santos Partnership: Fiocruz Objectives and results: Development of a new governance model in territories under exception situation, in Rio de Janeiro, with direct impact on the participating management of SUS and public policies. This way, the project may produce knowledge in a shared basis, to be appropriated by the members of the many councils and by the institutions member of the Sustainable Manguinhos Network for the promotion of the social and cultural and environmental equity and sustainability in Manguinhos. Title: Clinic data, bioequivalence and generic drugs: an analysis of India and Brazil Code: PRES-004-LIV-12 - Official Number: 2010-164 Period: 11/11/2011 to 10/31/2013 Coordinator: Claudia Inês Chamas Partnership: Agence Nationale Recherche (SIDA) Objectives and results: Analysis of the process under development, in the South countries, of the infrastructure and the skills required for the compliance of a standard now international regarding generic drugs. Title: Qualification of surveillance actions for meeting the goals of the Health Surveillance strategic agenda Code: PRES-005-LIV-12 - Official Number: 25380.004162/2011-81 Period: 12/19/2011 to 12/19/2012 Coordinator: Fernando Jose Marques de Carvalho Partnership: Fiocruz Objectives and results: The project actions aim at: restructuring the Transmissible Diseases Surveillance System; expanding the response capacity of the National Health Surveillance System to the public health and disasters emergencies; preparing a surveillance strengthening plan in the hospital scope, an integrated plan for the elimination of hanseniasis and other neglected diseases and a strategic action plan for combating non-transmissible chronic diseases; supporting the implementation of surveillance of non-transmissible diseases and injuries (DANT) and risk factors in the priority states and municipalities and capitals; expanding the coverage and improving the quality of mortality and morbidity information. The project will act in three different blocks: transmissible diseases; non-transmissible diseases, analysis of the health situation and health promotion, Environmental Surveillance and Worker’s Health and Management of the National Health Surveillance System. Title: Building sustainable capacity for the research on health and its social determiners in low and medium income countries (SDH-Net) Code: PRES-006-LIV-12 - Official Number: 282534 Period: 02/06/2012 to 02/06/2016 Coordinator: Paulo Marchiori Buss Partnership: European Commission-Gtz German Technical Cooperation

60 Objectives and results: Supported by the 7th Framework Program of the European Community (FP7), the project focus is to construct and strengthen the link of the health research competencies with its social determiners in Africa and in the low income countries of Latin America, by means of close collaboration with the European partners. The idea is developing innovating tools for strengthening the research capacity in the DSS area, including the development of methodologies and research planning. Participation in the consortium funded by the European Community, whose objective is to construct, strengthen and connecting the health research with its social determiners in Africa and in Latin America, in low and medium income countries (PRBM), in close collaboration with the European partners. Title: Support to the development of social technologies on health Code: PRES-007-LIV-12 - Official Number: 25380.004134/2011-64 Period: 12/30/2011 to 12/30/2013 Coordinator: Jose Leonidio Madureira Souza Santos Partnership: Fiocruz Objectives and results: Consolidate the social policies promoted by the Growth Acceleration Program (PAC) in the territory of Manguinhos and in Colônia Juliano Moreira (Jacarepaguá) and structuring the social and organizational capital of vulnerable groups and segments for participating in SUS and public policies. Title: I Territorialized Research and Development Meeting of the Fiocruz campus of the Atlantic Forest Code: PRES-008-LIV-12 - Official Number: w/o no. Period: 04/26/2012 to 04/27/2012 Coordinator: Gilson Antunes da Silva Partnership: Pan American Health Organization (OPAS) Objectives and results: Defining the guidelines for consolidating and developing an ecology and health platform in the Fiocruz campus of the Atlantic Forest (CFMA); and promoting the integration of the set of actions making the grounds for the Platform of Social Technologies on Health of CFMA, favoring also the incorporation of new methodologies. Title: Implementation of the partnership center of Canal Saúde Code: PRES-009-LIV-12 - Official Number: 25380.000213/2012-87 Period: 03/27/2012 to 03/27/2013 Coordinator: Marcia Correa e Castro Partnership: Fiocruz Objectives and results: Structuring of a partnership center, in the Canal Saúde scope, setting actions resulting in the increment of the channel’s programming, whether by co-production actions, or by the acquisition of the exhibition rights for audiovisual products. Title: Health remote guidance project Code: PRES-010-LIV-12 - Official Number: 010/2012 – SMS-G Period: 05/21/2012 to 05/20/2013 Coordinator: Paulo Gadelha Partnership: Municipal Health Department of São Paulo and Fiocruz Objectives and results: Planning, development, implementation and operation of a visual communication platform – named health remote guidance – aimed first at servicing pregnant women and their babies in the first year of life in the municipality of São Paulo, registered and identified as high risk, by the Program Mãe Paulistana. One of the subprojects is “Alô Mãe”, a health phonecenter, connecting mothers and their families to a nurse team specialized in obstetrics, ready for offering guiding, labor or emergency care, 24x7. The program is focused on monitoring pregnant women and children until their first year – especially those with potential risk factors – serviced by the Unified Health System (SUS). Upon the registration, the program identifies the cases requiring individual monitoring and defines a monitoring plan according to its complexity, with weekly, monthly or more frequent contacts. The identification and management of potential risk cases allow preventive measures and a health proactive management. The demands monitoring assists action and services planning in a dynamic way, ensures the access to the proper resources and promotes the communication among professionals, institutions and users. Title: Kari-Oca celebration of people Code: PRES-011-LIV-12 - Official Number: PA 75/2012 Period: 06/15/2012 to 08/15/2012

61 Coordinator: Fernando Jose Marques de Carvalho Partnership: Fiocruz Objectives and results: Holding of Kari-Oca 2012 and the Indigenous Green Games as one of the events related to Rio+20, in the area to be constructed according to the specific Brazilian indigenous engineering, integrated to the environment in a sustainable way, creating a space for indigenous people from several countries to meet their cultures, traditional sports, their relationship with the environment. Title: Institute of Development Studies (IDS) cooperation project having the International Health Affairs Center (CRIS-Fiocruz) as intervening party Code: PRES-012-LIV-12 - Official Number: 12/017 Period: 05/01/2012 to 08/30/2012 Coordinator: Paulo Marchiori Buss Partnership: Institute of Development Studies - IDS Objectives and results: Promoting the exchange between researchers and policy makers from the United Kingdom, BRICS (Brazil-Russia-India-China-South Africa) countries and other emerging countries related to the social development and health social determiners. Title: Support to two international cellular biology congresses: the International Tropical Medicine and Malaria Congress and the Brazilian Society of Tropical Medicine Congress Code: PRES-013-LIV-12 - Official Number: 25380.001269/2012-59 Period: 07/13/2012 to 11/13/2012 Coordinator: Fernando Jose Marques de Carvalho Partnership: Fiocruz Objectives and results: The Brazilian government has been creating different strategies in the area of science and technology for increasing the internationalization, including the health sciences areas. In this sense, major international events have been held in Brazil, more specifically in the city of Rio de Janeiro. The purpose of those events is creating a scientific excellence environment for the exchange of ideas, presentation of tools, methodologies, ensuring the participation of students and researchers from all over the world Title: Strengthening of research and technological development on health between Brazil and France Code: PRES-014-LIV-12 - Official Number: 25380.001197/2012 Period: 06/15/2012 to 06/15/2013 Coordinator: Paulo Marchiori Buss Partnership: Fiocruz Objectives and results: To strengthen and expand the efforts between Brazil and France seeking innovative solutions on health, the science and technology field, as well as expanding the exchange of human resources in the educational relations, especially led by the Fiocruz units and, hence, the improvement of results and the scientific and technological relationship between the two countries, through their scientific institutions. Title: Fauna handling and zoonoses control program Code: PRES-015-LIV-12 - Official Number: 25380.000316/2012-47 Period: 07/24/2012 to 07/24/2014 Coordinator: Gilson Antunes da Silva Partnership: Fiocruz Objectives and results: The Fiocruz campus of the Atlantic Forest (CFMA) is in the region of Jacarepaguá, which represents nowadays one of the main urban growth fronts of Rio de Janeiro. It is on the border between natural and anthropic ecosystem, which ranges from a highly populated area, through a less populated region, up to a forest. In this context, the need for developing a zoonoses control program comprising domestic and farm animals as well as wild animals present in the CFMA. Title: Qualification of the Ministry of Health’s strategic planning actions Code: PRES-016-LIV-12 - Official Number: 25380.2444/2012-25 Period: 10/10/2012 to 04/09/2014 Coordinator: Fernando Jose Marques de Carvalho Partnership: Fiocruz Objectives and results: The presentation, approval, monitoring and assessment criteria for programs and projects are critical for ensuring the effectiveness of the Ministry of Health’s de-centralized action. It requires the development

62 of capacities and methodologies able to handle the complexity and diversity of situations resulting from the several institutional arrangements, through which the Ministry of Health develops its decentralized activity. For the implementation of such actions, the proposal is to apply strategic planning tools, through participative methodology resulting in qualification and improvement of the corporate planning system of the Ministry of Health. The activities of this project and the results expected include: processes of production, storage and distribution of health information oriented in a standardized way; strengthened and qualified processes of management of the technical cooperation of the Ministry of Health with international organizations; strengthened and expanded government purchase processes; methods and processes allowing monitoring and assessing several actions, institutionalized in the Ministry of Health scope, in a systematic and standardized way; strategic information for the Ministry of Health and SUS management made efficiently by using technologies ensuring its attainment, production and distribution; monitoring and assessment system implemented for the Ministry of Healthâ&#x20AC;&#x2122;s technical cooperation projects with international organizations and excellence hospitals, for assisting the monitoring, the production of managerial information and decision making; methodology for defining the physical infrastructure investments created and implemented for strengthening the National Health Investments Plan; systematized and disseminated information for qualifying the SUS management subsidizing the decision-making process as well as the PNS, PE and priority brands assessment and monitoring; process of the Ministry of Health strategic planning monitoring systematized and supported in a efficient way, by means of technologies ensuring the attainment, production and distribution of strategic information for the management of the Ministry of Health and SUS; Ministry of Health teams and partner institutions qualified and operating in the learning culture way from the permanent application of monitoring and assessment to the processes; strategic agenda of the federal manager together with the actors involved in PNS and PE, in order to allow the characterization of opportunities, threats, strengths and weaknesses presented by the environment to the implementation of actions of the federal management of SUS. Title: Study Workshop on health, environment, governance and sustainable development Code: PRES-017-LIV-12 - Official Number: 107032-001 Period: 09/10/2012 to 05/09/2013 Coordinator: Paulo Marchiori Buss Partnership: International Development Research Centre - IDRC Objectives and results: Workshop for presenting and analyzing methodologies and experiences with interface between investigation, formulation of policies and strategies, and intersectoral interventions. The conclusions and recommendations will be presented in a second workshop about management and governance with the participation of leaders in the health, environment and development sectors. Title: Qualification of SUSâ&#x20AC;&#x2122;s strategic planning and fund management actions Code: PRES-018-LIV-12 - Official Number: 25380.001035/2012-10 Period: 12/13/2012 to 06/12/2014 Coordinator: Paulo Ernani Gadelha Vieira Partnership: Fiocruz Objectives and results: The development of capacities and methodologies able to handle the complexity and diversity of situations resulting from the several institutional arrangements, through which the Ministry of Health develops its decentralized activity, is essential. This institutionalized knowledge acts for promoting the continuous improvement of the technical cooperation to be provided to the state and municipal health departments and to the health funds, through measures enabling the quality and agility in the SUS funds transfer, as well as ensuring innovation and sustainability in the implementation of the management processes of the Ministry of Health relevant to the consolidation of SUS, as provided by the Complementary Act no. 141/2011. In this sense, the project aims at qualifying the execution, monitoring, follow up and assessment processes of the investments in physical and equipment infrastructure, as well as the analysis of account rendering and the reformulation of investment projects. It aims also at improving the management and control of fund investment upon the setting of mechanisms enabling the demonstration of the further application of the minimum percentage which was not invested in measures and public health services in the previous year. The project includes also the integration, upon automatic processing, of the SIOPS information to the electronic centralized system for controlling the transfers of the Federal Government to the other entities of the Federation. Finally, it aims at promoting the qualification of managers and work teams in the SUS scope, by developing assessment researches, preparing technical documents, methodological instruments, setting standards and rules and training workshops for supporting the implementation of the new guidelines and processes related to the request of investment resources.

63 Title: Itaboraí Forum: Policy, Science and Culture on Health Code: PRES-019-LIV-12 - Número Oficial: 25380.001802/2012-82 Period: 10/23/2012 to 10/23/2013 Coordinator: Felix Julio Rosenberg Partnership: Fiocruz Objectives and results: Palácio Itaboraí is the seat of the Forum, being a permanent room for thinking and ideas generation. Its main purpose is to gather intellectuals, scientists, artists, managers and users of education and health of Brazil and abroad, for generating formulation of policies and practices to reduce the impact of the economic and social inequalities in health.

65 Title: Information, communication and disclosure on health and science and technology for SUS and the society Code: VPEIC-001-LIV-12 - Official Number: 25380.003121/2011-78 Period: 12/30/2011 to 04/30/2013 Coordinator: Fernando Antonio Pires Alves Partnership: Fiocruz Objectives and results: Macro project set in the VI Internal Congress, considering as strategic orientation the strengthening of the information, communication and disclosure on health and science and technology and innovation on health, for assisting the process of formulation and implementation of policies, programs and interventions on public health. Title: Excellence program for Strictu sensu graduation in Fiocruz Code: VPEIC-002-LIV-12 - Official Number: 25380.003120/2011-23 Period: 12/30/2011 to 12/30/2012 Coordinator: Maria Cristina Rodrigues Guilam Partnership: Fiocruz Objectives and results: The program will assist the graduation strengthening efforts and its interaction with the scientific and technologic production and innovation on health, by means of collaborative networks for overcoming the main health issues affecting the Brazilian population. Title: Professional master’s degree on Family Health Code: VPEIC-003-LIV-12 - Official Number: 25380.004282/2011-89 Period: 12/28/2011 to 12/28/2013 Coordinator: Maria Cristina Rodrigues Guilam Partnership: Fiocruz Objectives and results: The challenges placed for the graduation on health resulting from the implementation of the Family Health strategy over the national territory require educational innovations and the cooperation between education and health research institutions, as well as from the health services network. It will be developed in network, in a de-centralized way, by the collaborating and agreed institutions. Title: Preparation and publication of the executive report of the VIII Brazilian Congress on Epidemiology Code: VPEIC-004-LIV-12 - Official Number: 25380.004195/2011-21 Period: 12/22/2011 to 05/22/2013 Coordinator: Nísia Verônica Trindade Lima Partnership: Fiocruz Objectives and results: Production and disclosure of the report for the event held by Abrasco and its partners, with publication in the Abrasco’s Brazilian Epidemiology Magazine. Title: Preparation and implementation of the development and training of human resources on health surveillance Code: VPEIC-005-LIV-12 - Official Number: 25380.004196/2011-76 Period: 12/28/2011 to 12/28/2013 Coordinator: Nisia Veronica Trindade Lima Partnership: Fiocruz Objectives and results: Enabling technical cooperation efforts for the preparation, implementation, monitoring and assessment of the development and training program for human resources on health surveillance, in order to improve the technical and management capacity of the Unified Health System. Title: 6th Brazilian Health and Environment Olympics: work assessment, awarding and disclosure phases Code: VPEIC-006-LIV-12 - Official Number: 25380.001425/2012-81 Period: 07/18/2012 to 07/18/2013 Coordinator: Cristina Araripe Ferreira Partnership: Fiocruz Objectives and results: The Brazilian Health and Environment Olympics (Obsma) is an educational project aiming at fostering the development of interdisciplinary activities in the Brazilian schools, encouraging teachers and students to make works addressing the issues and problems regarding human health, environment and the interfaces between the two themes in a critical, responsible and constructive way. With the main purpose

66 of contributing to the thinking and positioning of young students about the health promotion and the environmental challenges faced by the Brazilian society, the Obsma encourages, supports and discloses, in several instances, creative and innovative pedagogical activities and projects, standing out in the contest. In its 6th edition (2011-2012), the national project is still willing to know and acknowledge relevant initiatives/works performed by school teachers and students over the Brazilian territory, from the 6th to the 9th grades of the elementary school and the high school, on health and environment. The project activities include: monitoring the registration process and the demands from teachers, students and education institutions received by phone, e-mail and media; organization and holding of six meetings of the regional assessing committees (Mid West, Minas-South, Northeast I, Northeast II, North and Southeast); assessment of the 477 works registered and validated in this edition; organization and holding of the meeting of the national assessing committee, of the event of national awarding, in the city of Rio de Janeiro; organization of the travelling and stay of the 62 teachers and students awarded nationally; monitoring of the contracting of services provided for the disclosure and execution of the project (purchases, payment of third parties, issuance of tickets etc.); press advisory in the disclosure and awarding phases of the project; maintenance and permanent updating of the website www.olimpiada. fiocruz.br; generation of contents and monitoring of social networks (Facebook, YouTube and Twitter); support to initiatives of regional coordinations; and organization and performance of workshops during the National Science and Technology Week (October 2012). Title: Implementation of the Fiocruz unit in the state of PiauĂ - phase I Code: VPEIC-007-LIV-12 - Official Number: 25380.001782/2012-40 Period: 09/13/2012 to 09/13/2014 Coordinator: Nisia Veronica Trindade Lima Partnership: Fiocruz Objectives and results: Implementation of new unit in the state of PiauĂ due to the strategy of regionalization and consolidation of the National Health Science and Technology (C&T) Network, upon the institutional expansion of Fiocruz to the least developed regions of the country, under the guidelines of the Mais SaĂşde - Direito de Todos 2008/2011 Program of the Ministry of Health, focused on the growth, wellbeing and improvement of life conditions of the Brazilian citizen.

69 Title: Rio Geração Consciente Code: VPGDI-001-LIV-12 - Official Number: 008/2011 Period: 12/15/2011 to 06/30/2013 Coordinator: Jose Leonidio Madureira Souza Santos Partnership: Local Government of the city of Rio de Janeiro Objectives and results: Graduating 150 young communicators for multiplying the consumers’ rights culture in three popular communities in the city of Rio de Janeiro – Manguinhos and Maré complexes and Santa Marta community. The project will develop in those territories three solidary communication spots, where the youngsters will have, over 10 months, 600 training hours, including theoretical and practical classes, for qualification on the communication content and techniques. Title: Implementation of AIDS and other STD surveillance, prevention and control efforts Code: VPGDI-002-LIV-12 - Official Number: 25380.004219/2011-42 Period: 12/28/2011 to 11/05/2014 Coordinator: Pedro Barbosa Partnership: Fiocruz Objectives and results: Performance of a broad set of studies and investigations on the knowledge, attitudes and practices Research on Knowledge, Attitudes and Practices (PCAP) of the population under higher risk; improving the epidemiologic, clinical and behavioral surveillance related to the target public; identifying the prevention and assistance efforts aimed at PHVA (people living with aids) and their higher risk groups. Title: Strengthening of Fiocruz efforts in Rondônia Code: VPGDI-003-LIV-12 - Official Number: 25380.000729/2012-21 Period: 04/18/2012 to 04/18/2014 Coordinator: Rodrigo Guerino Stabeli Partnership: Fiocruz Objectives and results: Strengthening of the strategies of implementation of the Fiocruz unit being installed in Rondônia, mainly by strengthening of human capital and improving of work conditions. Title: Strengthening of the Casa de Oswaldo Cruz training office activities Code: VPGDI-004-LIV-12 - Official Number: 25380.001003/2012-14 Period: 06/18/2012 to 06/18/2013 Coordinator: Nara Margareth Azevedo Partnership: Fiocruz Objectives and results: Expanding the negotiations with public and private institutions through actions and sponsorship helping make financially feasible some of the unit’s strategic projects. Title: Specialization course on Family Health Basic Care Code: VPGDI-005-LIV-12 - Official Number: 25380.002186/2012-87 Period: 10/16/2012 to 10/16/2015 Coordinator: Rivaldo Venancio Da Cunha Partnership: Fiocruz Objectives and results: To consolidate the educational activities for the professionals participating in the Basic Health Care Professional Appreciation Program (PROVAB), making feasible the development of knowledge, abilities and attitudes required for the good performance of their functions, contributing to the development of the quality of health care provided to the population.

71 Title: Assessment of the national pharmachem production sector: technological and productive training Code: VPPIS-001-LIV-12 - Official Number: 25380.004188/2011-20 Period: 26/12/2011 to 26/12/2012 Coordinator: Jorge Carlos Santos da Costa and Jorge Bermudez Partnership: Fiocruz Objectives and results: Updating the diagnosis on the industry training of the national pharmachem sector, as continuity to the study made in 2007 by mapping and identifying the companies acting in Brazil; assessing the infrastructure, human, technical and financial resources capacity of the industries installed and analyzing the innovative actions of the Brazilian pharmachem companies. Title: Study on pharmaceutical equivalence, dissolution profile and relative bioequivalence/bioavailability of the drug Terizidona Code: VPPIS-002-LIV-12 - Official Number: w/o no Period: 06/22/2012 to 07/22/2013 Coordinator: Lais de Bastos da Fonseca Partnership: Riemser Arzneimittel AG Objectives and results: Performance of study on pharmaceutical equivalence, dissolution profile and relative bioequivalence/ bioavailability of the drug Terizidona. Title: Performance of the analytic study phase of relative bioequivalence or bioavailability of the drug Haloperidol 05 mg Code: VPPIS-003-LIV-12 - Official Number: w/o no Period: 05/21/2012 to 05/21/2013 Coordinator: Lais de Bastos da Fonseca and Valeria Esteves Partnership: Laborat贸rio Teuto Brasileiro S/A Objectives and results: Development and validation of bioanalytical process methodologies from different biologic matrices, focusing on the pharmacokinetics studies and on the quality of drugs, a procedure required for the relative bioequivalence and bioavailability to the knowledge on the drug behavior in the human organism.

3.3 - Funding agents The main funding agents for the projects executed by the several technical and scientific and technical and administrative units of Fiocruz, having Fiotec as intermediary, are represented in the charts by the percentage ratio of their interest over the total fund executed.

4.1 - Project financial handling The table and chart below show the fund sources by the main trade instruments applied in Fiotec, as well as the percentage interest of each in relation to the total amount raised. PREMISES

CONVENTIONAL

SPECIAL

TOTAL

CAC

R$ 3.918.541,35

R$ 4.373.690,73

FDI

R$ 2.296.917,00

FIO

R$ 1.082.000,00

INO

R$ 2.046.645,51

LIV

R$ 205.369.546,34

R$ 511.783.158,89

R$ 728.462.914,96

TOTAL

R$ 214.713.650,20

R$ 511.783.158,89

R$ 738.262.168,20

The volume of fund raised by projects until December 2012 was of R$ 738,262 million. Added to that, R$ 3,602 million raised with income from financial investments in checking accounts exclusive for projects, totaling R$ 741,864 million. The table below shows the total raised per Fiocruz unit, with the income included. Total raised with Projects Total raised with financial investments project exclusive accounts -SUBTOTALTotal administrative fees raised - Fiotec -TOTAL-

R$ 738.262

[+]

R$ 3.602

[+]

R$ 741.864

[=]

R$ 31.116 4,19% R$ 710.748

[-] [=]

4.2 - History Data: From 2012 the funds raised with projects started to be measured by the project categories named as conventional, special and international. The tables and charts below show the raising variation of those project categories in 2012 compared to the same period of 2011. The values include the total raised with financial investments, as specified in item 4.1. FUNDS RAISED VALUE EVOLUTION - R$/thousand YEAR

CONVENTIONAL

SPECIAL

INTERNATIONAL

TOTAL

2011

255.435

291.627

16.512

563.574

2012

216.820

512.872

12.173

741.865

FUNDS RAISED PERCENTAGE EVOLUTION - % YEAR

CONVENTIONAL

SPECIAL

INTERNATIONAL

TOTAL

2011

45,32

51,75

2,93

100,00

2012

29,23

69,19

1,64

100,00

Graphic design Caio Tayano Diagramming Caio Tayano Content Emilia Wien / Luiz CecĂlio de Barros/ Christianne Barbosa / Manuella Garcia / Priscila Sakurada Review Manuella Garcia / Emilia Wien Christianne Barbosa / Priscila Sakurada