Instant Notes in Bioinformatics, Second Edition

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NEW FROM GARLAND SCIENCE

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“I would have no hesitation in recommending this book to any teacher or student of bioinformatics, at almost any level. Many researchers will also find it useful.” Briefings in Bioinformatics – on the First Edition

Instant Notes in Bioinformatics, Second Edition illustrates how bioinformatics can be applied by all informatics students to most aspects of the life sciences. The book is divided into three parts: Part One: An introduction to bioinformatics and its application to biology. Part Two: The Building Blocks of Informatics: the physical, mathematical, statistical and computational bases of bioinformatics, with the use of biological examples. Part Three: The Biological Application Domains: divided into three subgroups, molecular biology, metabolism/anatomy/physiology, and complex information sources. The interconnections between the Building Blocks and Application areas throughout the text are highlighted, illustrating the foundational importance of, and reliance on, the Building Blocks from all of the Application areas.

September 2009 300 pp: 116 figures: 34 tables Paperback: 978-0-415-39494-9: £20.00

KEY FEATURES l Concise

introduction to the subject which focuses on the core material a structured approach to learning l Covers both theory and applications l Ideal for short courses and for those needing to grasp the subject quickly and easily l Artwork will be available at www.garlandscience.com/instant_notes.asp upon publication l Provides

THE AUTHORS Charlie T. Hodgman and Andrew French, both at the Multidisciplinary Centre for Integrative Biology, School of Biosciences, University of Nottingham, UK David R. Westhead, School of Biochemistry and Microbiology, University of Leeds, UK


CONTENTS A. The Changing Face of Research Biology B. Definitions of Bioinformatics C. Essentials of Physics D. Data and Databases E. Data Categories F. Computation G. Probability and Statistics H. Modelling and Mathematical Techniques I. Artificial Intelligence and Machine Learning

J. Genomes and Other Sequences K. Transcriptomics L. Proteins and Proteomics M. Metabolomics N. Supramolecular Organization O. Biochemical Dynamics P. Physiology Q. Image Analysis R. Text Analysis Index

TEXTBOOKS OF RELATED INTEREST Mathematics for Biological Scientists Mike Aitken, Bill Broadhurst and Stephen Hladky, all at the University of Cambridge, UK Mathematics for Biological Scientists is a new undergraduate textbook which covers the mathematics necessary for biology students to understand, interpret, and discuss biological questions.

2009 470 pp: over 200 color illustrations Paperback: 978-0-8153-4136-9: ÂŁ32.00

Contents Introduction 1. Quantities and units 2. Numbers and equations 3. Tables, graphs and functions 4. Shapes, waves and trigonometry 5. Differentiation 6. Integration 7. Calculus: expanding the toolkit 8. The calculus of growth and decay processes 9. Descriptive statistics 10. Probability 11. Statistical inference 12. Biological modelling End of Chapter Questions Presenting Your Work

Understanding Bioinformatics Marketa J. Zvelebil, Institute for Cancer Research, UK and Jeremy O. Baum, Imperial College, UK Suitable for advanced undergraduates and postgraduates, Understanding Bioinformatics takes a conceptual approach. It guides the reader from first principles through to an understanding of the computational techniques and the key algorithms.

2007 772 pp: 586 figures Paperback: 978-0-8153-4024-9: ÂŁ42.99

Contents Part 1: Background Basics Part 2: Sequence Alignments Part 3: Evolutionary Processes Part 4: Genome Characteristics Part 5: Secondary Structures Part 6: Tertiary Structures Part 7: Cells and Organisms Appendix A. Probability, Information, and Bayesian Analysis Appendix B. Molecular Energy Functions Appendix C. Function Optimization Further Reading List of Symbols Glossary Index


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