NEW SECOND EDITION
Molecular Driving Forces Statistical Thermodynamics in Biology, Chemistry, Physics, and Nanoscience
Ken A. Dill and Sarina Bromberg Molecular Driving Forces, Second Edition is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. It demonstrates how the complex behaviors of molecules can result from a few simple physical processes, and how simple models provide surprisingly accurate insights into the workings of the molecular world. Widely adopted in its First Edition, Molecular Driving Forces is regarded by teachers and students as an accessible textbook that illuminates underlying principles and concepts. This Second Edition includes three new chapters: (1) “Microscopic Dynamics” describes the microscopic basis for dynamical processes and single-molecule processes; (2) “Molecular Machines” describes how nanoscale machines and engines work, and how energy is transduced into actions; (3) and “The Logic of Thermodynamics” was added in response to requests from users of the First Edition to describe more of classical thermodynamics, including more details on the distinction between reversible and irreversible processes. New practical applications, examples, and end-of-chapter questions are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanoscience. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts.
KEY FEATURES • Writing is readable, friendly, and accessible, and leads students step-by-step throughout. • Carefully crafted figures streamline complex data to promote conceptual understanding. • Simple models, such as lattice models, encapsulate complex processes. • Selection of topics prepares students for an interdisciplinary world—in chemistry, biology, physics, material science, environmental science, and nanoscience. • Includes the most extensive and modern applications of current physical chemistry books. • Worked examples in chapters explain key concepts and show their practical application. • Contains all the math and physics needed for students. • Appropriate as a physical chemistry book at several levels, from undergraduate chemistry or bioengineering to graduate physics and biophysics. • Each chapter contains end-of-chapter problem sets, references, and suggestions for further reading.
Garland Science November 2010 720 pages 690 illustrations Paperback 978-0-8153-4430£49.00
rland Science vember 2010 0 pages 0 illustrations perback 8-0-8153-4430-8 9.00
TABLE OF CONTENTS 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16.
Principles of Probability Extremum Principles Predict Equilibria Heat, Work & Energy Multivariate Calculus Entropy & the Boltzmann Law Thermodynamic Driving Forces The Logic of Thermodynamics Laboratory Conditions & Free Energies General Forces, Maxwell’s Relations & Mixtures The Statistical Mechanics of Simple Gases & Solids What Is Temperature? What Is Heat Capacity? Chemical Equilibria Equilibria Between Liquids, Solids, & Gases Solutions & Mixtures The Solvation & Transfer of Molecules Between Phases Physical Kinetics: Diffusion, Permeation & Flow
17. 18. 19. 20. 21. 22.
Microscopic Dynamics Chemical Kinetics & Transition States Coulomb’s Law of Electrostatic Forces The Electrostatic Potential Electrochemical Equilibria Salt Ions Shield Charged Objects in Solution 23. Intermolecular Interactions 24. Phase Transitions 25. Cooperativity: The Landau, Ising & Helix-Coil Models 26. Adsorption, Binding & Catalysis 27. Multi-site & Cooperative Ligand Binding 28. Bio & Nano Machines 29. Water 30. Water as a Solvent 31. Polymer Solutions 32. Polymer Elasticity & Collapse 33. Polymers Resist Confinement & Deformation Appendices
Visit www.garlandscience.com/mdf2 to view sample chapters.
NEW IN THE SECOND EDITION • A chapter on “Microscopic Dynamics” introduces nonequilibrium statistical mechanics, including the dynamics of single-molecule or few-particle systems. • Another chapter explores the principles of molecular machines: how ATP drives proton pumps and molecular motors, and how signals and information are transduced in biology, for example. • And a third new chapter, “The Logic of Thermodynamics”, expands coverage of classical thermodynamics. • A section has been added on how batteries and fuel cells work. • Purely mathematical topics are moved to the appendix. • New applications, worked examples, and end-of-chapter problems, keep the book fresh and relevant.
SUPPLEMENTS The following supplements are available to qualified instructors and may be requested via e-mail from garlanduk@tandf.co.uk. • PowerPoint® slides and JPEGs of the figures and micrographs. • Solutions Manual for end-of chapter problems.