Viruses: Biology, Application and Control

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VIRUSES BIOLOGY | APPLICATIONS | CONTROL

DAVID R. HARPER Viruses.indd 1

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VIRUSES BIOLOGY|APPLICATIONS|CONTROL

Viruses: Biology, Applications, and Control is a concise textbook for advanced

undergraduate and graduate students and is an updated and expanded version of the Second Edition of David Harper’s Molecular Virology. Focusing on key mechanisms and developments, Viruses presents many recent scientific advances, including virus evolution, emerging infections, virus extinction, control of infections, antiviral drugs, gene therapy, bacteriophage therapy, and diagnostics.

The first chapters introduce the reader to the structure and nature of viruses, including their classification and evolution. As viruses cause widespread and serious disease, the ensuing chapters explain how they interact with the immune system and the different ways we try to defeat them: vaccines, antiviral drugs, and immunotherapy. Laboratory methods for viral detection and laboratory diagnosis are also covered. While viruses do cause disease, many do not, and their special biology means they can have beneficial uses and this aspect of viruses is included. One of the most interesting areas in virology, given extensive coverage here, is how new viruses emerge and establish themselves.

Viruses: Biology, Applications, and Control is a rigorous treatment of the molecular

side of virology and its conceptual approach makes it an essential text for students and non-specialists.

THE AUTHOR David R. Harper is the founder and Chief Scientific Officer at AmpliPhi Biosciences. He was formerly at the Department of Virology, Barts and The London School of Medicine and Dentistry, UK

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Garland Science • July 2 346 pages • 220 illustrat Paperback: 978-0-8153-4150-5

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FEATURES

1. Virus Structure and Infection 2. Virus Classification and Evolution 3. Virus Replication 4. Immune Response and Evasion 5. Vaccines and Vaccination 6. Antiviral Drugs 7. Beneficial Use of Viruses 8. Emergence, Spread, and Extinction 9. Viruses, Vectors, and Genomics 10. Culture, Detection, and Diagnosis Appendix 1: Viral Replication Strategies Appendix 2: Current Antiviral Drugs

Instructor Resources • Figures from the book in JPEG & PowerPoint® formats • Selected animations

Online Supplements

Table of Contents

• Viral replication strategies of the major virus groups causing human infections are included in a dedicated appendix • Covers the emergence of new viruses, for example SARS, bird flu, and Ebola, and attempts to eradicate known viruses such as smallpox and polio • Key Concepts and Further Reading at the end of each chapter • Depth-of-understanding problems, for student review and classroom

discussion, help the reader apply theoretical material to real-world issues

Student Resources • Hints to answering the depth- of-understanding problems • Online glossary • Selected animations Will be available at

www.garlandscience.com/viruses

PRE-PUBLICATION REVIEWS

land Science • July 2011 pages • 220 illustrations k: 978-0-8153-4150-5 • £41.00

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“The organization of the book suits the organization of my course. The strengths are accurate information, the writing is professional and clear, the diagrams enhance the text, and there is quite a bit of valuable information in a book of this size.”

Stephen Rice, University of Minnesota, USA

“This is an excellent small book that covers the subject comprehensively. I would certainly recommend this to students on my course.”

Sheila Graham, IBLS, University of Glasgow, UK

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