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WORLD’S CLINICAL LABORATORY NEWS LEADER ISSN 1068-1760
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Vol. 39 No.1 • 2-3/2022
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Marker Predicts Sepsis in Critical Patients
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epsis has been reported as a major cause of increased morbidity, length of stay and mortality among patients hospitalized in Intensive Care Units (ICUs) for any cause. The survival of patients developing sepsis in the ICU is strictly related to an early
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Novel Protein Biomarkers Evaluate Prostate Cancer Aggressiveness
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rostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often
fatal outcome. In order to be able to treat prostate cancer more efficiently, it is necessary to understand the complex processes in the tumor at the molecular level. Though multiple genomic and transcriptomic-based analyses have been
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Simple Rapid Test Identifies Genetic Mutations in Cancer Cells for Personalized Therapy
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nvestigators have developed an extremely sensitive test to detect and quantify, from a routine blood sample, DNA fragments containing rare genetic mutations in cancer cells. Faster and cheaper than current methods, the assay can be performed on widely available instruments. See article on page 4
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Rapid Antigen Screening for Bladder Cancer
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rinary bladder cancer (BC) is the tenth most prevalent cancer affecting mainly the elderly and men. The suspicion of BC often arises after the detection of microscopic or macroscopic (gross) hematuria during a patient’s examination. An accurate urinary marker for BC could be valuable in identifying high-risk patients and reducing the number of control Cont’d on page 12
D-Serine Clearance Helps Measure Kidney Function
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valuation of kidney function is essential in daily clinical practice. The measured glomerular filtration rate (mGFR) using exogenous inulin has been considered as the gold standard of kidney function, though this procedure is labor intensive, time consuming, and expensive. D-Serine is a candidate biomarker of kidney function. D-Serine circulates the blood Cont’d on page 10
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Smartphone App with LAMP Kit Rapidly Detects COVID -19 / Flu Virus
COVID-19 Update. . . . . 5
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n a potential game changer for COVID-19 pandemic control efforts, a new cell phone app and lab kit have transformed a smartphone into a COVID-19/flu detection system. The detection system developed by a team of research scientists at UC Cont’d on page 14
Sensitive Protein Assay Differentiates Parkinson’s from Other Synucleinopathies
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team of British researchers adapted a sensitive analytical method to evaluate the diagnostic value of a real-time quaking-induced conversion (RT-QuIC) assay for assessing disease progression, stratification, and conversion in synucleinopathies such as
Parkinson’s disease. Synucleinopathies (also called alpha-synucleinopathies) are neurodegenerative diseases characterized by the abnormal accumulation of aggregates of alpha-synuclein protein in neurons, nerve fibers, or glial cells. There are three Cont’d on page 24
Clinical News. . . . . . 4-26 IFCC News. . . . . . . . . . 25 Product News . . . . . 6-28 Industry News . . . . . . . 29 Events Calendar . . 30-31
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