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WORLD’S CLINICAL LABORATORY NEWS LEADER ISSN 1068-1760
Vol. 36 No.3 • 5/2019
DAILY CLINICAL LAB NEWS
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Blood Test Detects Severe Transplant Rejection ung transplant recipients have the shortest survival rates among patients who get solid organ transplantation of any kind, as only about half live past five years. Lung transplant recipients face a high incidence of chronic rejection, which occurs when the
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Inflammatory Bowel Disease Linked to Prostate Cancer bout one million men have inflammatory bowel disease in the USA, a common chronic condition that includes Crohn’s disease and ulcerative colitis. Epidemiologic studies have noted an association between chronic inflammation and prostate cancer.
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Prostate cancer is cancer that occurs in the prostate, a small walnut-shaped gland in men that produces the seminal fluid that nourishes and transports sperm. Prostate cancer is one of the most common types of cancer in men. Usually prostate cancer grows Cont’d on page 16
Blood Test Detects Alzheimer’s Before Symptoms Appear
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n international team of researchers identiA fied ten protein features
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Simple Inexpensive Test For Esophageal Cancer ancer of the esophagus claims more than 400,000 lives around the world each year. With no efficient, reliable method of screening for the disease, by the time symptoms become apparent, it’s often too late to save the patient. In 2016, the USA saw nearly 17,000 new cases diagnosed and about 16,000 deaths from cancer of the esophagus. Those numbers
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Bile Acid Blood Test Predicts Stillbirth Risk
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Newborn Cytomegalovirus Test Cleared for Marketing
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ytomegalovirus or CMV is a common virus that infects people of all ages. In the USA, nearly one in three children are already infected with CMV by age five and over half of adults by age 40
Clinical News . . . . . . 4-42 IFCC Annual Report . . 19 IFCC News . . . . . . . . . . 43 Product News . . . . . 6-42 Industry News . . . . . . 49 Events Calendar . . . . . 50
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Cancer-Associated Circular RNAs Catalogued Across Tumors
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ntrahepatic cholestasis of pregnancy (ICP) is caused by a build-up of bile acids in the blood, and symptoms include pruritus. ICP is a liver disorder affecting approximately 5,300 pregnancies annually in the UK, more than 14 every day. ICP is diagnosed in women with gestational pruritus and increased serum bile acids, and can be complicated by preterm labor,
See article on page 5
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to form a biomarker panel for Alzheimer's Disease before the appearance of any symptoms. By differentiating future Alzheimer's patients from among cognitively unimpaired individuals, such a blood test would be of key benefit toward coping with the disease.
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ircular RNA is a type of RNA which, unlike the better known linear RNA, forms a covalently closed continuous loop, i.e., in circular RNA the 3’ and 5’ ends normally present in an RNA molecule have been joined together. Circular ribonucleic acids (cir-
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cRNAs) are an intriguing class of RNA due to their covalently closed structure, high stability, and implicated roles in gene regulation. Scientists have begun to catalogue and have started characterizing circRNAs found across cancer types, including proposed circRNA Cont’d on page 4
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