LabMedica International October 2018

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WORLD’S CLINICAL LABORATORY NEWS LEADER ISSN 1068-1760

Vol. 35 No.6 • 10/2018

DAILY CLINICAL LAB NEWS

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Simple Blood Test Devised for Hepatitis B

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Extracellular RNA Helps Diagnose Medical Conditions

iral hepatitis is a major global health problem, and estimates suggest that hepatitis B was responsible for about half of the 1.45 million viral hepatitis-related deaths that occurred worldwide in 2013. A simple inexpensive blood test has been devised

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or some diseases, biomarkers can be used to determine how far the illness has advanced, but not shed light on how quickly it will progress in the future. Circulating extracellular RNAs (exRNAs) have the potential to serve as biomarkers for a wide

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range of medical conditions. However, limitations in existing exRNA isolation methods and a lack of knowledge on parameters affecting exRNA variability in human samples may hinder their successful discovery and clinical implementation. A new way has

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Microfluid Application To Enable Noninvasive Prenatal Testing

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urrently, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is estimated to affect more than one million people in the USA, and up to 24 million people worldwide. This often-debilitating condition is characterized by feelings of extreme exhaustion, muscle and joint pain, and insomnia, as well as difficulty concentrating or remembering things.

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here is no accurate method for distinguishing between the hypervirulent strain from the classical strain of Klebsiella pneumoniae (cKp), which is most often seen in the Western hemisphere, and is less virulent and usually causes infections in hospital settings. Several biomarkers have been discovered that can accurately identify hypervirulent K. pneumoniae (hvKp), a pathogen

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Point-of-Care Test Diagnoses Respiratory Viruses from Saliva

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he use of saliva as a specimen for the detection of respiratory viruses has been proposed as an alternative to nasopharyngeal aspirate or nasopharyngeal swab. Saliva may have the advantage to cause less discomfort in patients and less risk for healthcare workers.

Clinical News . . . . 4-33

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Events Calendar . . . 34

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Genetic Connections Uncovered Between Psychiatric Disorders

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Biomarker Discovered for Hypervirulent Pathogen

Image: Dr. Marnie Winter examining fetal trophoblastic cells isolated using inertial microfluidics

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breakthrough application of inertial microfluA idics technology toward the efficient isolation of trophoblastic cells from maternal peripheral blood, could lead to noninvasive prenatal diagnosis testing, thereby replacing current invasive procedures such as amniocentesis and chorionic villus sampling.

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rain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a consid-

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erable challenge. Over the past century, the classification of brain disorders has evolved to reflect the medical and scientific communities’ assessments of the presumed root causes of clinical phenomena such as behavioral change, loss of motor Cont’d on page 5

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