MCQ-Basic Science

FRCPath Part1 Course

Basic Science Cell injury and cell death EMQ 1 A. Liquefactive necrosis B. Coagulative necrosis C. Fat necrosis D. P53 E. Bcl-2 F. Metastatic calcification G. Dystrophic calcification H. Caesous necrosis Necrosis pattern in Brain abscess Necrosis pattern in Myocardial infarction Necrosis pattern in acute pancreatitis Apoptosis promoter Apoptosis inhibitor Patient with Paget’s disease showing foci of calcification in skin

MCQ 2 A kidney tumour shows histology of oncocytoma. The tumour cell have…

A. B. C. D.

Increased lipids Increased mitochondria Cytoskeleton abnormality Increased glycogen

Acute and chronic inflammation MCQ 3 A patient develops lung abscess. Which mediator is responsible for fever?

A. Prostaglandins B. Macrophages C. C3a &C5a D. TNF and IL-1 MCQ 4 A patient suffers from pneumonia and develops septic shock. In majority of cases it is caused by endotoxin (lipopolysacchride) present on…

A. B. C. D.

Gram positive bacteria Gram negative bacteria Fungi Parasite

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FRCPath Part1 Course

Generic disorder MCQ 5 Fragile X syndrome has which of the mutation: A. Point mutation B. Frameshift mutation C. Missense mutation D. Trinucleotide repeat mutation EMQ 6 A. Autosomal dominant inheritance B. Autosomal recessive inheritance C. X-linked recessive inheritance D. Trisomy Marfan syndrome Cystic fibrosis Fragile X syndrome Huntington disease Haemophilia Edward syndrome

Disease of immunity MCQ 7 Which type of hypersensitivity reaction is involved in systemic lupus erythematosus?

A. Type I B. Type II C. Type III D. Type IV Neoplasia MCQ 8 A person has medullary carcinoma of thyroid, phaeochromocytoma, parathyroid hyperplasia. Which gene mutation is present here?

A. MEN1 B. RET gene C. BRCA 1 D. APC MCQ 9 A newborn developed congenital rubella infection. Which of the following is not a manifestion of rubella infection?

A. Patent ductus arteriosus B. Tetralogy of Fallot C. Ventricular septal defect D. Atrial septal defect

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