Annual Report 2015
A medical university A
(Dnr 1-638/2015)
COVER PHOTO Marie CarlĂŠn at the Department of Neuroscience is one of the researchers using optogenetics to examine complex structures in the brain. The method makes it possible to turn individual cells on and off in order to study their function in detail. Optogenetics has quickly resulted a lot of new knowledge about which neurons give rise to various functions in the brain. Photo: Gustav MĂĽrtensson.
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KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
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The Vice-Chancellor’s statement A university dependent on every single employee
Internationalisation – the future is global
Every day all our employees go to their work at Karolinska Institutet, KI, with a common objective – to make a significant contribution to the improvement of human health. It is a vision that we share with many other medical universities around the world. Based on this vision, we now have an extensive network and good international cooperation with universities, other departments and companies.
KI currently partners with a large number of international universities, in both research and education. We are now working on a long-term strategy for how, and with which international partners, we are to collaborate. We want to strengthen our global partnerships and support universities in low- and middle income countries. We also want our students to be well equipped to meet opportunities and challenges at the global level.
KI – building for the future
Innovation and industrial collaboration – a way to give back knowledge
Deeper cooperation with the healthcare services The Stockholm County Council, SCC, is our single most important partner. About half of KI’s activities are carried out in close collaboration with the healthcare services. Following more than a year’s intensive work, we now have a new regional agreement to regulate collaboration between KI and SCC. Through this agreement, the parties will work together to promote advances in healthcare by expanding cooperation in the areas of translational and clinical research, education, development and innovation. Following this, KI and SCC will draft a joint, long-term strategy for collaboration on university healthcare in the Stockholm region. Translational and clinical research shall be given optimal conditions in the healthcare system. Placements within KI’s study programmes will to a greater extent take place in environments that have a very high quality of care as well as qualified and adequate supervision. KI and SCC will also make joint advances in the area of informatics so as to effectively meet the need for patient data from records, quality registers and biobanks and for other information needed in healthcare and research. The results of research will benefit patients by means of a well-developed organisation and process for applying and disseminating knowledge in healthcare, and by means of an effective innovation process.
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Innovation acitivities are assuming an increasingly prominent role at KI. These focus on several important questions, such as the creation of a new management structure enhanced with international expertise. A structured follow-up of performance and additional funding models are also prioritized issues. I see innovation as an important component in all study programmes, and we need new forms of partnership between the university and various actors in industry.
Thank you! In the past year, KI has received strong support and great generosity through donations and grants from private individuals, foundations and other funding bodies, and to all these I would like to extend a warm thank you.
Karin Dahlman-Wright Acting Vice-Chancellor Photo: Erik Cronberg.
In the past year, many of the initiatives we started while developing Strategy 2018 have begun to take shape. The construction of the research laboratory, Biomedicum, is in progress, as is work on the adjacent building for comparative medicine. 2015 work was started to build Neo at the Huddinge campus, a building that will primarily bring together basic research in immediate proximity to Karolinska University Hospital and the Royal Institute of Technology’s (KTH) new establishment. By renovating existing premises, we are also creating the “Future Laboratory”, with construction planned to start in the summer of 2016. I am particularly pleased that we are able to offer our students an entirely new learning environment on the Huddinge campus, an inviting milieu of 1000 square metres for studies and social interaction.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
The students have the floor Undergraduate students and doctoral students at Karolinska Institutet are represented by the two student unions, the Medical Students’ Association, MF, and the Student Union of Odontology, OF. The unions work primarily with student influence, students’ rights and student life. KI has the goal of seeing student representation at all levels of the organisation. For those of us who are active in student unions, this goal opens up great opportunities for exerting influence, but it also places demands on us. In order to achieve the high objectives KI has set for being a leading university, student representation must work effectively and the unions must have a voice in that process. It is as a unified university KI can achieve its objectives. The unions look forward to continued collaboration in a common direction. In the past year, the unions participated in a great number of different processes and decisions that have had an impact on all students at KI. At the beginning of 2015, the members of our union presiding committees were invited to a tour of the planned learning environments on the Huddinge campus. A former laboratory that once belonged to the Dental Technology programme was to be converted into lecture halls, seminar rooms and interactive IT environments. An exciting and modern project that we students had the chance to submit our views on. Almost a year on, we now eagerly await the opening! A little later in the spring, we met employees at KI’s Communications and Public Relations Office to discuss alternative ways to reach students. The consensus was that too many e-mails, though well meant, can easily be seen as spam. Instead, we student representatives required a greater physical presence of various kinds in order to get messages through today’s media noise. In 2015 the Student Health Centre wanted to get a clearer profile among students, which the unions have encouraged. We have met on several occasions during the year in order to improve
the situation for students. The knowledge that there is someone to turn to is hugely important if there is a need to speak with someone in confidence about relationships or stress, for example. Among other things, these meetings have resulted in the Student Health Centre coming into contact with students at our introductory events and contributing something positive and health-promoting. The Student Health Centre also arranged lectures on health and lifestyle during a joint day of sports. It is clear that there is a great demand for this kind of activities, and the plan is to increase these activities in the future. In November was the KI’s pro-vice-chancellor election performed, in which around 20 students participated. We made sure to vote for the person who had the clearest profile and the most expansive visions for education issues. An extremely important task and a prerequisite for continued student representation by the unions was submitting the application for union status in September. This process is carried out every three years and is done separately for each union. With little insight into what was expected of us, we took on this task: to provide a compilation and detailed description of our activities in order to try to look into the future and say what the union would be like in ten years and to justify why we need more resources for our study-related events. For us members of the presiding committee, this was an extremely demanding process, but all those hours of work were certainly worth it! Both unions have retained their union status and we were also in agreement with the university management regarding a more generous support for the activities of both unions in the future. This means that we will be able to arrange even better welcome activities for newly admitted students, even more alternatives at our sports days, better social activities and that we will be able to continue monitoring the study situation of all students at KI – and this is of course what everything we do is about.
On behalf of the Medical Students’ Association and the Student Union of Odontology
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Petter Berg, Chair of the Student Union of Odontology 2015 Photo: Erik Cronberg.
Photo: Private.
Jennie Sporre, Chair of the Medical Students’ Association 2015
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Key indicators 2015
2014
2013
2012
2011
6,062 72% 155 5,534 170 107 50% 395 60% 2,069 58% 770 58% 122 61% 3.10 4.44 359 8 n/a n/a
5,978 72% 160 5,613 170 74 56% 408 59% 2,071 58% 650 59% 281 57% 2.56 4.37 340 9 4,858 1,039
6,014 73% 147 5,589 158 51 64% 373 55% 2,090 59% 595 64% 375 62% 2.41 4.24 306 12 4,752 1,020
5,885 73% 154 5,307 170 34 57% 438 57% 2,111 60% 572 65% 380 63% 3.03 4.26 359 14 4,334 1,048
5 815 73% 146 5 351 159 10 54% 409 61% 2 045 62% 544 64% 349 62% 2.56 4.21 349 14 4,149 1,028
4,694 61% 5,193 853 48% 776 45% 372 29%
4,473 62% 4,924 844 47% 739 43% 367 28%
4,283 63% 4,736 827 46% 717 42% 373 28%
4,192 64% 4,716 846 46% 714 41% 367 27%
4,109 65% 4,699 845 47% 707 41% 347 26%
Revenue, total (SEK million), of which Bachelor’s and Master’s education (SEK million) – direct government funding (%) – external revenue (%) Doctoral education and research (SEK million) – direct government funding (%) – external revenue (%) Costs, total (SEK million) – staff – premises
6,475 1,050 86% 14% 5,424 35% 65% 6,394 53% 12%
6,156 1,007 86% 14% 5,149 37% 63% 6,078 52% 13%
5,796 991 88% 12% 4,805 37% 63% 5,797 52% 13%
5,646 954 87% 13% 4,692 37% 63% 5,506 52% 12%
5,340 926 87% 13% 4,415 37% 63% 5,188 53% 11%
Premises costs per m2 (SEK)
3,415
3,438
3,386
3,118
2,916
Balance sheet total (SEK million), of which – unexpended grants – change in capital for the year – administrative capital (incl. change in cap. for the year)
6,186 3 062 76 1,435
5,577 2,621 63 1,359
5,165 2,445 8 1,296
5,017 2,313 108 1,289
4,899 2,277 145 1,196
Education and research FTE, full time equivalent, students 1 – women Cost per FTE student (SEK thousand) APE, annual performance equivalents 1 Cost per APE (SEK thousand) Number of fee-paying students – women New doctoral student admissions – women Doctoral students, total >_ 10% activity – women Doctoral students with employment (FTEs) – women Doctoral students with doctoral grants (FTEs) – women Average study time, licentiate students (net) Average study time, doctoral students (net) Doctoral degrees awarded Licentiate degrees awarded Peer-reviewed scientific publications 2 Cost per peer-reviewed scientific publication (SEK thousand) 2
Staff FTE, full time equivalent, employees – women Average annual number of employees 3 Teaching staff (FTEs) – women Teaching staff with doctoral degrees (FTEs) – women Professors (FTEs) – women
Finance
1
Excluding doctoral students, contract education and contracted courses. Figure not given for 2015 owing to delay in registration, which would otherwise distort the statistics. The figures for 2011–2014 have also been adjusted due to the aforementioned delay in registration. 3 Average number of employees in April and October. Sources: The HR administration system Primula, the student database Ladok, The financial system Agresso. 2
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KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Content Highlights at Karolinska Institutet 2015...................................................................................................................... 8 Karolinska Institutet in brief..........................................................................................................................................10 KI’s commission and governance...............................................................................................................................................................................10 Organisation.......................................................................................................................................................................................................................10 Quality assurance..............................................................................................................................................................................................................10
Education...............................................................................................................................................................................12 Range of courses and study programmes...............................................................................................................................................................13 Students...............................................................................................................................................................................................................................13 Education............................................................................................................................................................................................................................15 Internationalisation..........................................................................................................................................................................................................16 Quality..................................................................................................................................................................................................................................18 Equal opportunities.........................................................................................................................................................................................................21 Special commitments.....................................................................................................................................................................................................21
Doctoral education...........................................................................................................................................................22 Doctoral students.............................................................................................................................................................................................................23 Quality..................................................................................................................................................................................................................................24 Internationalisation..........................................................................................................................................................................................................25 Equal opportunities.........................................................................................................................................................................................................25
Research.................................................................................................................................................................................26 New research findings – some examples.................................................................................................................................................................27 Quality..................................................................................................................................................................................................................................30 Research funding..............................................................................................................................................................................................................31 Strategic infrastructure....................................................................................................................................................................................................33 Internationalisation..........................................................................................................................................................................................................34 Equal opportunities.........................................................................................................................................................................................................35
Collaboration and innovation......................................................................................................................................36 Collaboration with Stockholm County Council....................................................................................................................................................37 Collaboration with the general public......................................................................................................................................................................38 Innovation support and collaboration with industry...........................................................................................................................................39 The innovation system....................................................................................................................................................................................................40
A university environment in development.............................................................................................................42 An attractive workplace in which to develop.........................................................................................................................................................43 Human resources report................................................................................................................................................................................................43 Recruitment........................................................................................................................................................................................................................45 Leadership and professional development.............................................................................................................................................................46 Work environment and employment conditions ................................................................................................................................................46 Equal opportunities.........................................................................................................................................................................................................46 Infrastructure....................................................................................................................................................................................................................48 Sustainable development............................................................................................................................................................................................49 Research and education for sustainable development.......................................................................................................................................49 Sustainable campus.........................................................................................................................................................................................................49
Financial report...................................................................................................................................................................50 Sources of funding...........................................................................................................................................................................................................51 Education at bachelor’s and master’s level..............................................................................................................................................................52 Research and education at doctoral level................................................................................................................................................................53 Asset management...........................................................................................................................................................................................................54 Funds.....................................................................................................................................................................................................................................54 KI Foundations..................................................................................................................................................................................................................55 Statement of financial performance..........................................................................................................................................................................56 Balance sheet.....................................................................................................................................................................................................................57 Internal control..................................................................................................................................................................................................................59 Appendix.............................................................................................................................................................................................................................60 The University Board.......................................................................................................................................................................................................66
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
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FEBRUARY
50
Photo: iStock.
MARCH
Silvia Doctors. The first cohort of Silvia Doctors graduates in May. These doctors have completed a master’s course in Dementia Care developed through cooperation between Karolinska Institutet and the Silviahemmet Foundation. Queen Silvia herself presents the diploma to the six doctors.
Spring Conferment Ceremony. Conferment Ceremony for Karolinska Institutet’s new doctoral graduates on 22 May. The ceremony is also attended by this year’s honorary doctors of medicine Tak W Mak, professor at the University of Toronto, Canada; Bertil Hållsten, founder of the Hållsten Research Foundation, Stockholm, Sweden; Barry Everitt, Professor of Behavioural Neuroscience at the University of Cambridge, UK and Mariam Claeson, Director of Maternal, Newborn and Child Health at the Bill and Melinda Gates Foundation, Seattle, USA.
MAY APRIL
Donation. Karolinska Institutet receives a donation of USD 50 million from Hong Kong-based businessman Ming Wai Lau. This funding makes it possible to start research activities in the field of regenerative medicine, with a Stockholm node and a Hong Kong node under KI’s direction. The purpose includes using stem cell technology to recreate damaged tissue in the heart, liver and nervous system.
JUNE State visits. Indian president is on a state visit. During the first ever visit made by an Indian head of state to Sweden, President Pranab Mukherjee visits Karolinska Institutet on 2 June together with King Carl Gustaf and Queen Silvia. The Government’s representative is the Minister for Higher Education and Research, Helene Hellmark Knutsson. In connection with an official stay in Sweden, President Jakaya Kikwete of Tanzania visits Karolinska Institutet.
Graduation season. End of semester means graduation. June sees celebrations for both newly graduated global Master’s students and Bachelor’s students. Their ceremonies are gilded with speeches and diplomas from university representatives and praise from family and friends. Photo: Ulf Sirborn.
JanuarY
Photos: Erik Cronberg.
Top-level meeting. Anders Hamsten, Vice-Chancellor of Karolinska Institutet, and Melvin Samsom, Hospital Director at Karolinska University Hospital, are featured in a joint interview by our in-house magazine KI Bladet at the beginning of the year. They agree that the major overall challenge is to improve the integration of the university and the university hospital and that highly qualified healthcare demands close cooperation with research, education and innovation.
Visits by ministers. The Minister for Higher Education and Research, Helene Hellmark Knutsson, visits Karolinska Institutet. One of the issues raised is that of more places in higher education in order to meet the demand that exists, not least in healthcare. The Minister for Enterprise and Innovation, Mikael Damberg, meets KI’s management in March. The Government is due to present its research policy bill in autumn 2016.
Photo: Gustav Mårtensson.
Highlights at Karolinska Institutet 2015
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Photo: Ulf Sirborn.
International. Karolinska Institutet and the Max Planck Society, Cologne, Germany, sign an agreement on the establishment of a new joint research laboratory at Karolinska Institutet specialising in congenital metabolic diseases. The collaborative programme will be led by a common research team leader and will engage researchers employed with both parties.
Photo: iStock.
Photo: Gustav Mårtensson.
million US-dollar
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Photo: Erik Cronberg.
SEPTEMBER OCTOBER
Photo: Erik Cronberg.
Pride. Around 120 people participate in the Pride Parade in Stockholm behind the Karolinska Institutet banner in early August. These included the initiators, Queerolinska, the HBTQ section of the Medical Students’ Association. KI’s management is represented by the University Director, the Deans of Education and Doctoral Education, many students and several employees.
Ministry for Foreign Affairs. Close to 150 ambassadors, Consul-Generals and other senior officials from the Ministry for Foreign Affairs visit KI as part of the Ministry’s annual conference to inspire and prepare its agency heads for the coming year. The programme focused on matters such as the role of research and education in creating international contacts.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
DECEMBER
Nobel Prize. This year’s Nobel Prize in Physiology or Medicine is awarded – the three researchers Satoshi Omura, William C. Campbell and Youyou Tu for discoveries that have saved millions of people from deadly and debilitating parasitic diseases. One of the three Chemistry Laureates is Tomas Lindahl, who made some of his crucial discoveries on DNA repair at Karolinska Institutet in the early 1970s. Congratulations, Tomas!
Neo. Cooperation was one of our favourite expressions when the turf was cut for a new research building on the Huddinge campus. The ceremony is held on 22 October adjacent to the main entrance of Karolinska University Hospital. Here – on a plot of ground still consisting of gravel and reinforcement bars – the Neo research building will be constructed next to an identical research building for KTH. In late 2017, researchers will already be able to move into Neo.
Photo: © ® The Nobel Foundation.
AUGUST
NOVEMBER
Photo: Gunnar Ask.
JULY
Network. The EU-funded network EurocanPlatform, which is coordinated from Karolinska Institutet, holds its final meeting in Brussels in November. The result is new partnerships between cancer centres around Europe that aim to transfer research discoveries from laboratory to clinic.
Photo: Erik Cronberg.
Anniversary. For 30 years, upper-secondary students have been able to spend their summers doing research through Karolinska Institutet’s biomedical summer research school. Over the course of seven weeks, students in their second or third year of upper-secondary programmes in natural sciences or engineering have the chance to actively participate in a research project at one of KI’s departments. This year, the summer research school turns 30 and this is celebrated with an anniversary symposium for and by former students.
Photo: iStock.
Photo: iStock.
Collaboration. A partnership between Swedish and Vietnamese universities is inaugurated in November. The Training and Research Academic Collaboration (TRAC) involves five Swedish higher education institutions and is coordinated by Karolinska Institutet. The goal is to develop an academic centre for education and research in order to contribute to the improvement of global health.
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ABOUT KAROLINSKA INSTITUTET
Karolinska Institutet in brief Karolinska Institutet’s, KI’s, vision is to significantly contribute to the improvement of human health. KI is a modern medical university that accounts for the single largest share of all academic medical research conducted in Sweden and has the largest range of medical courses and study programmes in the country. Our close connections with healthcare, extensive infrastructure and strong finances allow KI to conduct education and research of the highest quality.
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KI’s commission and governance
Organisation
KI’s commission has its basis in the Swedish Higher Education Act, which states that the university’s role is to offer courses and study programmes based on research and proven experience and to conduct research and development. The university is also required to collaborate with society at large and disseminate information about its activities. The following performance report is based on the university’s commission as set out by the Government in the Higher Education Act and the Appropriations Directions. Academic freedom, firmly established in law, provides extensive space for independent research and education. KI has only one faculty: medicine, which is carried out in a very decentralised organisation. KI’s governance model prescribes that the University Board is responsible for budget decisions concerning the organisation as a whole and the Vice-Chancellor makes decisions about further allocation of resources and annual duties based on adopted strategies and focus areas. During autumn 2015 KI established a three-year operational plan covering the years 2016–2018 that integrates the process for internal control. This process facilitates the implementation of KI’s Strategy 2018 and aims to clarify the key tasks and challenges that will be of significance to sustainability, continuity and renewal. The activities of Karolinska Institutet emanates in an area where fundamental values are of a particular importance. The public is entitled to place extensive demands on our approach and activities. For this reason, KI’s strategy is based on established core values expressing four principles to support the daily work of employees at the university. KI must safeguard the freedom of research, and our activities are to be characterised by: • a very high quality and an ethical approach, • trust and support for the initiatives, creativity, independence and skills of our employees and students, • good leadership, employeeship, inclusion, openness, equality and diversity, as well as care for the internal and external environments, • a strong social commitment and contribution to sustainable development within and outside Sweden’s borders through our education and research.
Research and education at KI are mainly carried out at 22 departments in the county of Stockholm. Karolinska University Hospital is adjacent to the campuses and has a vital role in clinical research and education. Collaboration also takes place with other hospitals and clinics in the nearby area. Together with the public real estate company Akademiska Hus, KI is undertaking a huge investment in new buildings and modern premises in order to better meet the needs of research and education. KI has actively participated in the planning of the urban quarter Hagastaden and the new university hospital while also developing its own campus in Solna. It is important to take advantage of the opportunities for cooperation and efficiency that the new university hospital can offer. The hospital is the university’s nearest neighbour in Solna and the plan is to connect the new research laboratory, Biomedicum, with the hospital’s research building. A corresponding structure is taking shape at KI’s southern campus in Flemingsberg. The infrastructure will provide better conditions for modern medical research which increasingly requires access to patients and advanced equipment. This should be shared and accessible to numerous researchers to make it cost efficient.
Quality assurance Quality above quantity is a key word in KI’s Strategy 2018. Quality goals are defined in policy and strategy documents. In May 2015, the Vice-Chancellor set up a project with the mission of creating an integrated quality management system for the university. A vital objective is to establish conditions for continuous quality improvement based on goals and quantifiable criteria that are expressed in Strategy 2018 and external requirements. This is carried out by a set of tools including continuous quality assurance and evaluation. Prerequisites for successful quality assurance procedures are the integration into everyday activities and recognition throughout the organisation. This will be our challenge during 2016.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Photo: Erik Cronberg.
ABOUT KAROLINSKA INSTITUTET
Daniela Duchens Harnisch and Sandra Leblons are medical students at Karolinska Institutet. Here you see them participating in a microscopy course during the second semester of their studies.
Karolinska Institutet, based in the Stockholm area, Sweden, conducts research and education on two campuses and at several of the county’s hospitals. Activities at KI’s departments are arranged at the following locations: Campus Solna and Karolinska University Hospital Solna Full-time equivalent students
2 684
Research revenue (million SEK)
3 141
Full-time equivalent employees
3 392
Campus Huddinge and Karolinska University Hospital Huddinge Full-time equivalent students
3 073
Research revenue (million SEK)
1 079
Full-time equivalent employees
1 214
VISION Karolinska Institutet significantly contributes to the improvement of human health.
MISSION Karolinska Institutets mission is to conduct research and education and to collaborate with society.
Strategy 2018 4 focus areas:
Danderyd Hospital Full-time equivalent students
243
Research revenue (million SEK)
38
Full-time equivalent employees
25 EMPLOYEES
Stockholm South General Hospital Full-time equivalent students
INFRASTRUCTURE
185
Research revenue (million SEK)
35
Full-time equivalent employees
35
COLLABORATION FUNDING
Swetox, Södertälje Research revenue (million SEK)
36
Full-time equivalent employees
27
A
EDUCATION
Karolinska Institutet has a unique range of study programmes in medicine and healthcare
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Photo: Erik Cronberg.
Jan Jakobsson, Adjunct Professor at the Department of Clinical Sciences, Danderyd Hospital, shows medical students Abraham Ibrahimson and Maria Rye how to initiate general anaesthetic before an operation. Using a vein catheter, the patient can be administered medication directly into a blood vessel.
EDUCATION
Photo: Gustav Mårtensson.
During the year, the Board of Higher Education has focused on securing the quality and research basis of study programmes. Part of this work involves extensive reorganisation to bring most programmes under the delegated responsibility of the KI departments. We have produced and implemented a more transparent model for allocating resources, and a project has been initiated to review the distribution and follow-up of research funding for teachers. The board has also worked strategically to increase internal dialogue and to make education issues visible.” Annika Östman Wernerson, Dean of Higher Education
13 BEGINNER’S PROGRAMMES
27 CONTINUATION PROGRAMMES
Range of courses and study programmes Karolinska Institutet, KI, has a wide range of study programmes in medicine and healthcare. This wide range is unique in Sweden. It is important that the range of courses and study programmes corresponds to student demand and labour market needs. According to labour market forecasts for the years ahead, there will be a great demand for the professions educated at KI. In 2015, KI offered over 40 study programmes and about 60 free-standing courses. The majority of the range offered are programmes leading to a professional qualification and supplementary education for those who already have an education in medicine and healthcare. This year has seen the start of a new master’s programme in molecular techniques in life science. The programme leads to a joint degree with Stockholm University and KTH Royal Institute of Technology within the framework of the Science for Life Laboratory (SciLifeLab).
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
60 FREE-STANDING COURSES
Students Applicants KI’s study programmes generally have a high number of applicants per admitted student. The number of qualified first-choice applicants continued to increase in 2015, but a rise in admissions figures led to a decrease in the number of applicants per admitted student. A lower number of applicants per admitted student can particularly be noted for one- and two-year master’s programmes, having increased for a couple of years. On the other hand, the number of applicants per admitted student for undergraduate programmes has increased and is unchanged for the specialist nursing programmes. Competition was greatest among applicants for the Study Programme in Medicine with eight qualified first-time applicants per student admitted, but the Study Programme in Psychology (5.6 applicants per student admitted) and the Study Programme in Dental Hygiene (5.0 applicants per student admitted) also had a high acceptance ratio.
Widening participation In 2015, KI responded to a survey from the Swedish Council for Higher Education (UHR) about KI’s work to widen participation.
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EDUCATION
Number of applicants per place by programme type (qualified first-choice applicants) 2012–2015 2012 Places Beginner’s
2013
Applicants/ place
Places
2014
Applicants/ place
Places
2015
Applicants/ place
Places
Applicants/ place
1,736
3.5
1,718
3.9
1,789
4.1
1,822
4.2
Continuation (excl. master’s)
843
2.4
905
2.2
915
1.9
974
1.7
Master’s
470
1.6
547
1.8
452
2.0
621
1.6
3,049
2.9
3,170
3.1
3,156
3.2
3,417
3.0
Total
Sources: UHR, NyA Open.
8,0
5,6
5,0
qualified first-choice applicants per student admitted to
qualified first-choice applicants per student admitted to
qualified first-choice applicants per student admitted to
STUDY PROGRAMME IN MEDICINE
STUDY PROGRAMME IN PSYCHOLOGY
STUDY PROGRAMME IN DENTAL HYGIENE
FTE students at KI (6,062)
6% 7%
27 %
3% 8% 3%
6%
11 %
In completing the survey, it became apparent that many of the activities that KI started in the early 2000s have today been implemented in core operations. Notable are KI’s Academic Writing Support and the opportunity to shadow a student. During the year, KI participated in UHR’s hearing on widening participation, which showed that work by higher education institutions would benefit from a clear definition of the concept of widening participation and from goals being set for this work. The survey and hearing results will form the basis of KI’s actions in 2016. KI has continued to take active part in Include, a network organisation for sharing experience and tools in widening participation matters.
Student influence
13 %
4% 7%
5%
Medicine 27 % Physiotherapy 6 % Nursing 13 % Psychology 5 % Dentistry 7 % Occupational therapy 4 % Other beginner’s programmes 11 % Biomedical laboratory science 3 % Specialist nursing (continuation) 8 % Other continuation programmes 3 % Master programmes 7 % Freestanding courses 6 % Source: Ladok.
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KI seeks to promote a study environment in which students, teachers and management take a joint responsibility for effective student influence. This is a prerequisite for achieving a very high quality of operations. According to the Higher Education Act, the primary task of a student union is to monitor and be involved in the educational development. The student unions at KI have the opportunity to appoint representatives to all bodies that have direct responsibility for education issues. In order for these bodies to be quorate, at least one student representative must be present, provided that such a representative has been appointed by the student union. During the year, KI has made a decision on which student associations will have the status of student union at the university for the period 2016–2018. An application for union status was submitted by two student associations – the Medical Students’ Association and the Student Union of Odontology. Both were granted student union status, with responsibilities for student influence and the monitoring of education within their respective areas of
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
EDUCATION
Revenue from commissions distributed by source of funding Number of degrees awarded 2012–2015 Degree
2012
2013
2014
2015
Professional qualifications
1,223
1,256
1,432
1,578
655
891
1,106
1,246
Total number of degrees
1,878
2,147
2,538
2,824
Total number of individuals
1,668
1,758
1,964
2,105
General qualifications
12 % 8%
45 %
5%
Source: Ladok.
Full-time equivalent students (FTEs) and annual performance equivalents (APEs) in contract education 2012–2015 2012
2013
2014
2015
Full-time equivalent students
250
241
304
279
Annual performance equivalents
222
188
274
249
20 % 10 % County councils and municipalities 45 % Higher education institutions 10 % Other government agencies 20 % Organisations and foundations 5 %
Source: Ladok.
Swedish companies 8 % Foreign financiers 12 % Source: Agresso.
activity. KI provides financial support for this, as well as for the students’ and doctoral students’ ombudsmen. KI organises annual training for students who participate in KI’s planning and decision-making bodies supporting student influence. The training focuses on laws and regulations and organisational and decision-making structures. It is offered in both Swedish and English.
Education Full-time equivalent students (FTEs) and annual performance equivalents (APEs) In 2015, the number of FTEs was 6,062 and the number of APEs was 5,534 within the framework of the funding cap. This is a small increase in the number of FTEs, but a decrease in the number of APEs compared with 2014. The APE figure is lower than the previous year for a number of programmes. This is partly attributable to the fact that the academic year consisted of 41 weeks, which is a week more than is normally the case. Each programme’s share of the total number of FTEs is illustrated in the pie chart on the left. The number of FTEs and APEs in the various programmes is shown in the table appendix.
Degrees The total number of degrees awarded has increased in comparison with 2014. This is a general increase as regards professional qualifications, which is largely due to previous increases in places on several programmes. The specialist nursing programmes now also lead to a one-year Master’s degree, which explains the great increase in general qualifications.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Commissions KI’s commissions include contract education and contracted courses from other higher education institutions and of other commissions. Revenues from commissions amounted to just under SEK 81.5 million in 2015, an increase of seven per cent compared with 2014. See the pie chart above for information on revenues from different sources of funding. Contract education In order to meet society’s need for continuing professional development of healthcare professionals, KI offers a wide range of contract education in the area of healthcare. In 2015, specialist courses, e.g. for nurses and dentists, psychotherapy courses and specialist competence courses (SC courses) constituted a major proportion of turnover. However, contract education covers almost 150 different education activities for a variety of professional categories. In particular, it is worth noting that the number of courses for personnel working with children and young people has increased and that our cooperation with the City of Stockholm has continued to develop. In 2015, the first cohort of medical doctors completed the Master’s Course in Dementia Care, and a corresponding course for occupational therapists and physiotherapists started for the first time. Online courses continue to represent a significant portion of KI’s contract education. The decrease in the number of FTEs and APEs is mainly due to fewer participants in the longer psychotherapy courses and to the fact that one of the specialist nursing programmes did not start during the year. Despite this, turnover increased, which is above all due to a greater scope of international commissions and a greater scope to commissions from municipalities. Several of these commissions concerned courses for which no education credits are awarded.
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EDUCATION
Student exchanges 2015 Incoming and outgoing students within exchange programmes
Number of incoming students to Karolinska Institutet
Number of outgoing students from Karolinska Institutet
NORTH AMERICA NORTH AMERICA
296
incoming students to Karolinska Institutet in 2015
31 31
157
outgoing students from Karolinska Institutet in 2015
32
32
SOUTH AMERICA SOUTH AMERICA
4 4
1
Internationalisation Internationalisation activities have been carried out in accordance with the action plan for 2014–2017. Objectives in the action plan are that global health issues must be integrated in compulsory education, that all study programmes have a compulsory course in English, and that student and teacher mobility increase. The objective is also to increase the number of non EU/EEA students on the global master’s programmes. The theme of KI’s Teachers’ Day 2015 was internationalisation and included discussion about global health objectives and courses in English. A plan has been produced for a number of activities on the theme of Global Health to be organised for KI’s teaching staff in 2016. During the year, KI has enhanced support for teachers with regard to teaching in English and teaching in the “international classroom”. Two half-day seminars for teaching staff were also arranged on these themes. The number of outgoing exchange teachers decreased during the year from 60 to 38. A comparison of recent years shows that teacher mobility tends to vary. The decrease is above all seen within the Erasmus programme, while there has been an increase within the Linnaeus-Palme programme, as several of the planning trips previously undertaken have led to continued cooperation. The number of incoming exchange teachers is relatively constant. During the year, the number of employees that participated in staff exchange within the Erasmus programme has increased, from two to twelve. KI has continued to arrange information events about teacher and student exchanges and social activities for participating
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teachers and students. The number of incoming students is higher than last year, and the imbalance between incoming and outgoing students remains. As in previous years there is very great interest, above all from European students, in coming to KI. A number of students do parts of their degree project work abroad at universities or companies outside exchange programmes. Some also participate in international courses such as Global Health and Medical Development in Europe and the EU, in which part of the tuition is carried out abroad.
Tuition fees for non EU/EEA students In 2015, KI offered one international bachelor’s programme and eight international master’s programmes. There were also a number of freestanding courses taught in English. KI had a total of 172 fee-paying students (91 women), which is an increase compared with the previous year. The number of FTEs was 107 and the number of APEs was 98. In the autumn term 2015, 58 new fee-paying students were registered on KI’s global master’s programmes. Of these students, 22 had a full scholarship, which is a 57 per cent decline compared with 2014. The trend form 2014 of more self-financed tuition-fee students continues.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
1
EDUCATION
ASIA ASIA EUROPE EUROPE
193
193
73
73
32 32
6 6
20
20
8
8 AFRICA
AFRICA
30 30
23
OCEANIA
23
OCEANIA
Source: Ladok.
KI has participated in the master’s programme Public Health in Disasters, which is an Erasmus Mundus cooperation with Universidad de Oviedo, Spain and Université catholique de Louvain, Belgium. Also in 2015, a number of Brazilian students on the Ciência sem Fronteiras scholarship programme chose to study at KI. Investments within KI’s tuition fee-funded operations benefit all of the university’s internationalisation and training activities. In addition to the reception services and service on campus, the tuition-fee financed activities contribute towards the funding of pedagogical development that is aimed at improving and developing teaching in the international classroom. These efforts have also contributed to internationalisation at the KI campus. For the third year running, tuition-fee financed activities showed a positive financial outcome. The surplus will be reinvested in these activities. Examples of reinvestments are improved career service and language workshops for international students. Cooperation with the Swedish Migration Agency has worked well. However, it should be pointed out that a number of students have been unable to accept their study places due to delayed residence permits. Some students state that they find the long processing time for extending their residence permit difficult.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Number of full-time equivalent students (FTEs) and annual performance equivalents (APEs) in tuition-fee financed activities 2012–2015 2012
2013
2014
2015
Full-time equivalent students
34
51
74
107
Annual performance equivalents
28
50
64
98
Source: Ladok. Revenue and costs for operations funded by tuition fees 2012–2015 (SEK million) 2012
2013
2014
2015
5,7
9,3
14,7
19.3
Costs
-5,9
-7,6
10,7
15.4
Total
-0,2
1,7
4,1
3.9
Revenue
Source: Agresso.
17
EDUCATION
Quality Measures to improve the quality of KI’s study programmes KI has continued to implement the proposals put forward in the 2013 report on the quality and research basis of KI’s courses and study programmes. A new definition of research-based education has been established and will be used as a guiding principle in KI’s courses and study programmes. In order to clarify the departments’ responsibility for education and for its quality and research basis, the organisational structure for education is being changed. This reorganisation commenced in January 2015 when responsibility for a number of study programmes was delegated to one department. In 2015, a further four departments have been making preparations to assume programme responsibility from 1 January 2016. As part of the work to develop an integrated quality management system for education at bachelor’s and master’s level, quality indicators are being identified. This work will continue over the course of 2016. An important step in enhancing the quality of KI’s study programmes is to secure a teaching faculty of high academic and educational competence. As part of this work, KI’s recruitment strategy is introducing a teaching career track. In 2015 an inventory was made of the competence of course directors for the
18
Study Programme in Medicine. Similar inventories will be made for the other programmes.
Use of performance-based resource allocation In 2015, KI received SEK 11.7 million in quality-based funding. These funds have primarily been used for quality improvement measures in the study programmes rated by the Swedish Higher Education Authority (UKÄ) as “very high quality”. The programmes have mainly used the funding for educational development and the development of international activities. Remaining funds have been used for overall investments in quality development, for example implementation of KI’s action plan for quality evaluation and the development of an integrated quality management system for education at Bachelor’s and Master’s level.
Professional development for teachers In 2015, KI arranged 14 courses on teaching and learning in higher education and a number of shorter continuing professional development courses for teachers. These courses had just over 400 participants in total. In addition a freestanding course with around 150 participants was organised for clinical teachers and supervisors in placement courses. KI also arranged a teachers’ day which focused on the internationalisation of education and involved around 200 participants.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Photo: iStock.
EDUCATION
14 courses David Martinsson, Linn Zetterström and Mitchell Isakka are students on the Master’s Programme in Bioentrepreneurship at Karolinska Institutet. A degree will give them a solid basis for working on the development and administration of life science projects and companies. Photo: Erik Cronberg.
Photo: Erik Cronberg.
on teaching and learning in higher education were arranged with a total of 350 participants
Pedagogical leadership training The leadership training programme which KI started in 2014 was concluded in 2015. The overall goal of the programme was to ensure the future supply of scientifically and pedagogically qualified leaders for educational activities at KI. The evaluation of the training showed that participants were very satisfied with both the structure and content of the course. There are plans to repeat this training in 2016.
200 participants at Teachers’ Day Internationalisation was the theme of KI’s Teachers’ Day 2015
Online courses Since 2013, KI has collaborated on Massive Open Online Courses (MOOCs) with the international education group edX. The purpose of MOOC activities is to develop and market KI study programmes globally in order to attract the best students. KI has developed six courses since the collaboration began. Three courses were developed in 2015, of which two were carried out. The third will be offered in 2016. During the year preparations have also been made to enable all MOOCs to be eligible as self-study courses.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
In 2015 KI developed three MOOCs in cooperation with the education group edX
19
EDUCATION
45% men
Gender distribution of beginners on continuation programmes Midwifery Psychotherapy Specialist nursing Odontological prophylactics Master’s 1 year Photos: Erik Cronberg.
Master’s 2 year
55% women
Total 0%
20%
40%
60%
Men
80% 100% Women
Gender distribution of beginners on beginner’s programmes Occupational therapist Audiology Biomedicine Biomedical lab sciences Physiotherapy Speech pathology and therapy
Medicine Midwifery Optometry
The Study Programme in Medicine has the most even gender distribution
Psychotherapy Psychology Specialist nursing Radiology
Nursing Odontological prophylactics Master’s 1 year Dental hygiene
Dentistry Master’s 2 year Total
77%
0%
20%
40%
Men
60%
80% 100% 80% Women Women
Source: Ladok.
of beginner students are women
20
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
EDUCATION
Equal opportunities Gender distribution A majority of first- and second-cycle students are women, and the proportion of men among beginner students has been at around 23 per cent over time. Some study programmes have no or only a few men, and it is only the Study Programme in Medicine that has a relatively even gender distribution. The recent trend of a greater proportion of men on master’s programmes appears to have been broken. Our recruitment initiatives involve active work for KI’s study programmes to be represented by both women and men, on KI’s website, in social media, at fairs and when visiting schools. It is, however, difficult to influence gender-related vocational choices.
In order to strengthen the equal opportunity perspective in the university’s study programmes, KI arranges lectures, workshops and seminars for supervisors and teachers. Harassment, discrimination, equal conditions for patients and gender disparities in health are among the subjects raised. During the year two teacher seminars were held on the theme of accessible teaching. The aim is to equip teachers with pedagogical tools which they can use when teaching students with disabilities. KI offers both students and employees the opportunity to take a web-based course on discrimination and harassment. This online course is available in both Swedish and English. In 2015 KI participated in Stockholm Pride together with the Medical Students’ Association and its student association Queerolinska. During the year KI’s Council for Equal Opportunities provided financial support for Heteroveckan, a studentdriven festival week with a norm-critical perspective. The year also included the inauguration of the intersectional book collection at the University Library. The aim of this collection is to supplement the library’s regular literature, particularly highlighting normcritical and intersectional perspectives in areas such as medicine, pedagogy and psychology.
Special commitments Supplementary training for persons with formal education in medicine, dental surgery and nursing from countries outside the EU/EEA. Together with the universities of Gothenburg and Linköping, KI has in 2015 arranged supplementary training for doctors, dentists and nurses who had completed their training in countries outside the EU/EEA. KI has a national coordination role. These courses cover one year’s full-time studies, half of which are theoretical and half clinical training. All three courses are developed in collaboration with the other participating institutions.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Photo: Erik Cronberg.
Equal opportunities in courses and study programmes
Cecilia Stening and Johan Tengberg are in semester 3 of the Study Programme in Medicine at Karolinska Institutet and are also histology tutors for medical students in semester 2. Histology is the study of biological tissue under the microscope. Studying tissue and its appearance can help to detect various diseases.
The year has seen intensive discussions on the expansion of the number of places within existing programmes and the opportunity to provide supplementary education for other occupational groups. KI has also received requests from the Swedish Public Employment Service to give preparatory courses and from the National Board of Health and Welfare to test knowledge and skills and to provide a course on Swedish statutes to all licensed professions.
21
DOCTORAL EDUCATION
Karolinska Institutet’s conferment ceremonies are arranged to formally celebrate the scientific achievements and the hard work involved in compiling and defending a doctoral thesis. At the conferment ceremony in the Stockholm City Hall, the new doctoral graduates receive their insignia; hat – the symbol for academic freedom and diploma – the written attestation of this dignity.
22
Photo: Stefan Zimmerman.
Karolinska Institutet’s doctoral students shape the research landscape of the future
DOCTORAL EDUCATION
Photo: Erik Cronberg.
A major focus for the Board of Doctoral Education in 2015 has been to increase internationalisation. The board has endeavoured to see more of our doctoral students spending a part of their education outside Sweden. We also want to increase our international collaboration on doctoral education, both with important foreign universities and within the framework of various Marie Skłodowska Curie programmes.” Anders Gustafsson, Dean of Doctoral Education
2,069 94 % 359 active doctoral students
would recommend KI
Doctoral education is an important aspect of activities at Karolinska Institutet (KI) and its doctoral students play a significant role in the research that is carried out. Responsibility for doctoral programmes has been delegated to the KI departments. It is above all the individual supervisors who ensure that the almost 400 doctoral students who graduate each year have developed into competent and independent researchers. For this to be possible, the university provides a framework that includes supervisor training, directors of studies at the departments, research schools, faculty resources for doctoral students as well as rules and guidelines.
Doctoral students This year’s results show no major changes in terms of the number of doctoral students, although a weak trend towards fewer new doctoral students is discernible. This is an expected development due to increased costs for doctoral students, which partly stem from doctoral grants having been restricted from two years to one
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
doctoral degrees
year. In 2016 the opportunity for doctoral grants is being removed entirely, which will further increase the cost for funding doctoral students. The decrease in the number of doctoral students with doctoral grants, from 17 per cent in the autumn semester of 2014 to 9 per cent in the autumn semester of 2015, is matched by an increase in the number of doctoral students with a doctoral studentship, from 45 per cent to 52 per cent. The increased cost has thus not meant that a higher proportion of doctoral students at KI have been recruited among those with external stipends or those with employment outside the university, but the departments have in most cases been able to offer a studentship instead. At the end of 2015, 2,069 active doctoral students were registered at KI. Of these, 935 reported that they carried on studies on a part-time basis during the autumn semester (10–99 per cent of full-time). In 2015, the proportion of newly admitted doctoral students who were eligible through education from a country other than Sweden was 37 per cent. The most well-represented countries are China (four per cent of all those newly admitted) and Western European countries such as Italy, the Netherlands, Denmark and Germany. It is important to note that the country where students became eligible for doctoral studies is not the same thing as the country of nationality or citizenship.
23
DOCTORAL EDUCATION
Doctoral education: admissions, registered students and degrees awarded 2012–2015 Degree
2012
2013
2014
2015
Doctoral admissions
438
373
408
395
– of which licentiates
15
9
9
7
2,111
2,090
14
12
9
8
359
306
340
359
3
10
6
7
Postgraduate students (acticve >_ 10%) Licentiate degrees Doctoral degrees – of which earlier licentiate degree
2,071 2,069
Source: Ladok.
Active doctoral students at KI 2012–2015 Number 2 500
2 000
1 500
Quality Third-cycle programmes of high quality means that theses of high scientific quality are produced, but also that KI awards degrees to employable, competent and independent researchers. Besides prominent research, this requires a learning environment characterised by good leadership, focused on doctoral students’ learning and development.
Third-cycle programmes – networks for doctoral students Third-cycle programmes are thematic networks for doctoral students with the task of coordinating the range of courses and other learning activities in the relevant research domain. The overall aim of these programmes is to contribute to a good learning environment beyond what is offered by the KI departments and research teams. During the year, the range of third-cycle programmes has been reviewed and requirements have been specified in order to clarify areas of responsibility and financial frameworks. Ahead of 2016, some programmes have been merged with other programmes, and a new third-cycle programme for cardiovascular research has been created.
Fulfillment of objectives
1 000
500
0 2012 Men
2013
2014
Women
2015 Total
Definition: Doctoral students that have had an activity rate of at least 10 per cent during the autumn semester. Source: Ladok.
Specified intended learning outcomes are used as a basis for planning an individualised programme for each doctoral student, and this makes it possible to focus on the student’s learning. Progress and fulfillment of objectives can then be monitored throughout the programme. This makes it easier to assess the learning progress and to introduce measures at an early stage if necessary. In 2015 a pilot study was carried out concerning an electronic system for following up the individual study plans. The system provides an overview of all doctoral students, which means that their studies can be followed up with greater quality assurance.
Follow-up Number of doctoral degrees awarded at KI 2012–2015 Number 400
300
200
100
0 2012 Men
2013 Women
2014
2015
Since eight years, all doctoral students have been invited to participate in an anonymous survey in connection with their thesis defence, an exit poll on their completed studies. The response rate in recent years has been stable at just over 80 per cent. The exit poll shows, for example, that 94 per cent of respondents in 2014 would probably recommend KI to prospective doctoral students (combined number of responses affirming the options “agree” and “somewhat agree”). This is a positive development as previous years’ responses were 91 per cent (2013), 86 per cent (2012) and 89 per cent (2011). In addition, a further survey was carried out in autumn 2015 concerning the learning and environment of doctoral students. This survey will also be addressed to doctoral students at several other universities in Europe, which will enable international comparisons. The results will be presented during 2016.
Total
Source: Ladok.
24
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Photo: Erik Cronberg.
DOCTORAL EDUCATION
Azadeh Karami, doctoral student at the Department of Neurobiology, Care Sciences and Society, conducts research on Alzheimer’s disease in the lab at Novum, Huddinge campus.
Internationalisation Among other things, KI’s Strategy 2018 states that a limited number of in-depth collaborations are to be further developed within doctoral education and that doctoral students are to be given opportunity to participate in international exchanges. Projects in the partnership with Stellenbosch University in South Africa and Makerere University in Uganda have been allocated additional money for doctoral education. During the year, 40 doctoral students have also received travel grants from KI of up to SEK 25,000 in order to carry out part of their doctoral education abroad.
international, institutionalised collaboration involving doctoral education at KI. The doctoral students in this programme share their time between laboratories at KI and at NIH and have supervisors from both organisations. In 2014, KI and NIH agreed to develop their collaboration and in 2015 planning for a new agreement began.
China Scholarship Council, CSC
Supervisor training, which is compulsory for new principal supervisors, includes a half-day session about equal opportunities, with topics as gender equality, discrimination and harassment. Supervisor training is offered several times a year adressing both current and soon-to-be supervisors. A complement to this training is KI’s online course on equal conditions, which is available to all students and employees. Since 2010, a section on equal opportunities has been included in the introduction day, which is mandatory for all newly admitted third-cycle students. KI also finances the Doctoral Ombudsman, who assists third-cycle students and is able to represent them. The exit poll also poses questions about harassment and discrimination in cases of dispute.
During the year, a collaboration agreement with CSC has been developed. The agreement covers stipends for five Master’s students, 30 doctoral students, 20 postdocs and five visiting researchers to KI. KI’s research teams have shown great interest in this initiative.
Singapore During the year, the collaboration agreements on joint doctoral student programmes were renewed with both the National University of Singapore and Nanyang Technological University.
National Institutes of Health, NIH (USA) Since 2001, KI has had an established doctoral student collaboration with NIH in the field of neuroscience. This is the largest
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Equal opportunities
25
RESEARCH
Annika Kinch, doctoral student at the Department of Clinical Sciences, Danderyd Hospital, conducts research on palliative patients with an implantable cardioverter-defibrillator (ICD). Patients already affected by, or who are at risk of being affected by, life-threatening arrhythmia can have an ICD implanted. An ICD monitors heart rate and can when necessary treat life-threatening arrhythmia by means of rapid pacemaker stimulation or an electrical shock to restore a normal rate. 26
Photo: Erik Cronberg.
Karolinska Institutet’s research breakthroughs contribute to the improvement of human health
RESEARCH
Photo: Erik Cronberg.
An increasingly important task for KI is collaboration with society at large. In the Stockholm region KI is developing its collaboration with Stockholm County Council (SCC) and with KTH Royal Institute of Technology and Stockholm University. There is also greater international cooperation with organisations and leading universities. KI is working actively to increase collaboration with parts of the regional and global pharmaceutical industry. Broad collaboration and interaction with society at large is a prerequisite for KI’s continued development.”
The percentage of patients who receive life-saving cardiopulmonary resuscitation has increased substantially thanks to volunteer SMS Lifesavers.
Good blood sugar control reduces the risk of problems following a bypass operation on Type 1 diabetes patients.
Karolinska Institutet, KI, has made continued efforts to enhance the preconditions that are necessary for taking further steps towards the absolute forefront of international research. This involves investments in infrastructure, both at the university and in collaboration with healthcare services. New career paths have been created, the conditions for strategic recruitment have improved and there is increased focus on competition for research grants. Collaboration with industry has been improved.
New research findings – some examples KI’s research covers the full range from basic studies in molecular biology to clinical studies and patient-focused research. Several of the academic works from 2015 concerned diseases affecting many people, such as cancer and cardiovascular disease. Some examples are provided below.
Patient studies point to survival factors The percentage of patients who receive life-saving cardiopulmonary resuscitation has increased substantially thanks to volunteer SMS
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Photo: Science Photo.
Photo: iStock.
Photo: Science Photo.
Hans-Gustaf Ljunggren, Dean of Research
A study reported risk factors for breast cancer diagnosed in the interval between two mammographic screenings.
Lifesavers (The New England Journal of Medicine, NEJM, June). CPR performed before the ambulance arrives doubles the chance of survival for patients suffering cardiac arrest (NEJM, June). Patients with a mechanical valve prosthesis had a better survival record than patients with a biological valve prosthesis. This finding might be of major importance since the use of biological valve prostheses has increased in all age groups in recent years (European Heart Journal, November). Another study identified income as an influencing factor: the higher a patient’s income, the better are his or her chances of surviving cardiac surgery in both the short and long term (Journal of the American College of Cardiology, JACC, October). Researchers were also able to establish that stored blood does not impair survival for cardiac surgery patients; blood stored between 14 and 42 days was just as safe as fresh blood (The Journal of the American Medical Association, JAMA, October).
How other diseases affect cardiovascular health It has been demonstrated that good blood sugar control reduces the risk of problems following a bypass operation in Type 1 diabetes patients (JACC, July). The already known increase in risk for negative effects following a bypass operation for diabetes patients was primarily seen in patients with Type 1 diabetes (JACC, April). Rheumatoid arthritis was linked to more serious symptoms and poorer outcomes in the event of acute heart problems (European Heart Journal, September).
27
RESEARCH
Finding yields more effective and better healthcare Researchers showed that a single blood test and an ECG can rule out the risk of myocardial infarction in patients seeking emergency care for chest pain. The researchers believe that this finding might be of major importance to the 15 to 20 million patients in the United States and Europe who seek emergency care for chest pain each year (JACC, April). Research was also able to show that Swedish healthcare had reduced the number of bleeding complications and had saved lives through the fast introduction of a new blood-thinning treatment for myocardial infarction (JAMA, February).
Heart muscle cells can be regenerated New human heart muscle cells can be formed, but this mainly happens during the first ten years of life. The results support the idea that it is possible to stimulate the rebuilding of lost heart tissue (Cell, June).
Risk factors for breast cancer have been mapped Many women who receive hormone therapy to lower the risk of breast cancer recurrence discontinue their recommended treatment. Different factors that increase the risk of discontinuing treatment have been identified (Journal of Clinical Oncology, June). Characteristics and risk factors for breast cancer diagnosed in the interval between two mammographic screenings were also reported (Journal of Clinical Oncology, February), and a third study demonstrated the link between some risk factors for breast cancer and disease prognosis (Journal of Clinical Oncology, November).
More precise cancer risk assessments are possible The removal of the fallopian tubes significantly reduces the risk for ovarian cancer (Journal of National Cancer Institute, January). Pregnancy does not increase the risk of relapse among women successfully treated for the Hodgkin’s lymphoma form of cancer (Journal of Clinical Oncology, December). Research also showed that the analysis of a biopsy from gastroscopy, an inspection of the stomach, oesophagus or duodenum, can predict the risk of developing stomach cancer (BMJ, July).
Detection of aggressive prostate cancer can be improved A new test for prostate cancer, known as the STHLM3 test, was presented. According to researchers, this is better at detecting aggressive cancer compared with current diagnosis using the PSA test (Lancet Oncology, November). One study was also able to explain why castration together with radiation increases the chance of survival for patients with prostate cancer compared with radiation therapy alone (Science Translational Medicine, November).
New findings on cancer treatments In oesophageal cancer operations it is common for the surgeon to remove a large number of lymph nodes in order to prevent the cancer from spreading and to increase the patient’s chance of survival. But according to a new study this did not influence the prognosis (Journal of National Cancer Institute, March). Researchers were also the first to suggest that cells in the tumour blood vessels contribute to a local environment that protects the cancer cells from tumour-killing immune cells. The results can contri-
28
bute to the development of better immune-based cancer therapies in the long term (Journal of National Cancer Institute, August).
Why we can halt when we walk A study identified a population of “stop cells” in the brainstem that are essential for the ability of mice to stop their locomotion (Cell, November). A new regulation mechanism for autophagy and eventually the death of dopamine-producing neurons in Parkinson’s disease has been described (Nature Neuroscience, April).
Brain training and healthy lifestyle may slow down cognitive decline It has been found that an intervention programme focusing on dementia risk factors can slow down cognitive decline in elderly people. During the two years the study ran, the risk of being affected by cognitive decline was 31 per cent higher in the control group than in the group that had been actively provided with advice on maintaining a healthy diet, participation in physical training and brain training and with support to manage cardiovascular risk factors (Lancet, March).
New methods simplify cell mapping Researchers presented a detailed map of cortical cell types and the genes active within them (Science, February). Researchers also presented a new method that makes it possible to identify new and previously unknown neuronal types and to gain an understanding of their function in relation to specific behaviours (Nature Biotech, December).
Small structures but great advances A study presented a simpler way to make nanostructures from DNA that are able to tolerate the low salt concentrations inside the body. This opens the way for new biological applications of DNA nanotechnology (Nature, July). Another study demonstrated that bone marrow cells can also form fat. The long-term hope is that this discovery could lead to new therapies for patients with metabolic diseases, in which adipose cells play a key part (Cell Metabolism, July).
New method can prevent suicide Suicidal behaviour can be prevented in young people using a method that teaches school pupils to detect mental ill-health in themselves and in their friends, and that also trains them to understand, interpret and handle difficult emotions (Lancet, January). A new study was also able to dismiss fears that the smoking cessation drug varenicline treatment increases the risk of adverse outcomes such as suicide attempts, psychoses, aggression and traffic accidents (BMJ, June).
Age of parents influences risk of autism The combined age of parents and large age gaps between parents can be linked to an increased risk of autism in children. The greater the age gap, the greater the risk their child will have autism (Molecular Psychiatry, June).
Malaria protection explained Researchers explained the mechanisms behind the protection that blood type O provides against severe malaria. (Nature Medicine, March).
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
RESEARCH
New research shows that gaining weight from one pregnancy to the next can increase the risk that women will risk a stillborn or lose their second babies within the first year of life. (Lancet, December). Bariatric surgery had both a positive and negative influence on the risk of complications during subsequent pregnancy and delivery. The results indicate that maternal health services should regard such cases as risk pregnancies (NEJM, February). Children born to women who were vaccinated against the H1N1 flu during their pregnancy did not have an increased risk of low birth weight, growth retardation or premature birth (BMJ, November).
One form of male infertility explained
Photo: Science Photo.
Pregnancy risks mapped
Pregnancy does not increase the risk of relapse among women successfully treated for the Hodgkin lymphoma form of cancer.
A study linked male infertility to autoimmune prostatic inflammation (Science Translational Medicine, June).
Crucial studies on abortion treatment
Photo: iStock.
Two studies presented results that might lead to new international recommendations for the treatment of medical abortions and miscarriages. One of the studies shows that it is possible to replace the clinical follow-up examinations recommended today for medical abortions with a home pregnancy test. The other study shows that midwives can safely and effectively treat failed abortions and miscarriages in rural districts of Uganda. (Lancet, March).
Risk genes identified in large-scale mapping Researchers at KI have been involved in a number of studies aiming to map genes and how they relate to diseases. For example, they have identified risk genes for breast cancer, atopic eczema, multiple sclerosis and aggressive skin cancer and have participated in studies concerning the link between genes and overweight (several studies in Nature and Nature Genetics, 2015).
It has been found that an intervention programme focusing on dementia risk factors can slow down cognitive decline in elderly people.
A study is the first to show that humans have genetically adapted to a polluted environment. Researchers have identified the gene that underlies the altered metabolism that protects some indigenous groups in the Andes of northern Argentina against exposure to arsenic. They have likely been exposed to high levels of arsenic in drinking water for thousands of years (Molecular Biology & Evolution, March).
Photo: Science Photo.
Human gene identified for tolerance to an environmental hazard
Research opens the way for new biological applications of DNA nanotechnology.
Environment more important for immune system than genes The environment drives human immune variation more than genes. The study also indicates that environmental influence on the immune system increases more and more as we age (Cell, January).
Why high-intensity exercise works Photo: iStock.
Researchers have identified a cellular mechanism behind the surprising benefits of short, high-intensity interval exercise (PNAS, from National Academy of Sciences, November). Research demonstrates that environmental influence on the immune system increases more and more as we age.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
29
RESEARCH
Number of published articles 2005–2014 7 000 6 000 5 000 4 000 3 000 2 000 1 000 0 2005
2006
2007
2008
2009
2010
2011
2012
Other
Editorial material
Review
Letter
Meeting abstract
Article
2013 2014
Source: Web of Science.
Field-normalised citation score 2005–2014 Citation score 1,75 1,50 1,25
0,75
2005 2006 2007
2008
2009 2010
KI
2011
2012 2013
Photo: Erik Cronberg.
1,00
2014
Global average
Source: Web of Science.
Andrea Strandberg, research assistant at the Department of Clinical Neuroscience, with equipment that is used to measure eye movement at the Marianne Bernadotte Centrum at St. Erik Eye Hospital.
Change in research funding 2006–2015
Quality
SEK million
3 500 3 000
Measures of academic output – bibliometrics
2 500 2 000 1 500 1 000 500 0 2006
2007
2008
2009
2010
External Source: Agresso.
2011
2012
Government
2013
2014
2015
KI and many other universities use bibliometrics to follow the dissemination and impact of research results. Bibliometrics involves the application of mathematical and statistical methods to articles, books and other communications media. Reported data2 should be seen from a long-term perspective. The number of published articles is a rough measure of academic output and depends on a variety of factors, such as the publication patterns of different disciplines. The bars in the figure on the top-left of the page represent published articles with addresses that can be connected to KI.
2 Certain
data included herein are derived from the Web of Science® prepared by THOMSON REUTERS®, Inc. (Thomson®), Philadelphia, Pennsylvania, USA: © Copyright THOMSON REUTERS® 2016. All rights reserved.
30
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
RESEARCH
Total research revenue 2012–2015 (SEK million) 2012
2013
2014
2015
Change 2014–2015 (%)
Funding source Research councils
729
800
844
969
14.8
Other government agencies
349
344
288
307
6.6
Municipalities and county councils
475
396
376
400
6.4
Swedish foundations and organisations
692
779
904
974
7.7
Foreign foundations and organisations
343
351
409
405
-1.0
Swedish companies
168
182
198
252
27.3
Foreign companies
73
85
94
89
-5.3
Dividends from KI funds
56
68
70
76
8.6
Financial income
50
35
18
6
-66.7
2,935
3,040
3,202
3,478
8.6
Total external funding Direct government funding
1,732
1,763
1,920
1,897
-1.2
Total
4,669
4,802
5,121
5,375
5.0
63
63
63
65
Proportion of external funding (%) Source: Agresso.
Figures are based on the year of publication and unfractionated calculation. Because there is a slight delay in the database being updated, complete statistics for the past year are not available at the time the annual report is published. This means that details for 2015 are not reported so as to provide a true and fair view of developments. The sub-items number of “articles” and “reviews” have increased by 47 per cent since 2005, and half the increase has taken place since 2010. For all reported sub-items, the increase in total since 2005 is about 52 per cent.
Field-normalised citation score The field-normalised citation score reflects the number of citations of the article compared to other articles of the same type, i.e. the same type of document from the same year and the same subject. An article’s score is 1 if it is cited as many times as the average number for similar articles. The centre graph on the opposite page shows the average value of the field-normalised citation score for all articles from KI. Changes from previous years are relatively small, which means that KI maintains a level above the world average. Published articles from 2015 cannot constitute the basis of stable and reliable results and have been excluded. Work on the integrated quality management system commenced in 2015 in accordance with Strategy 2018. This involves work to define and develop quality indicators and quality improvement processes. This work will be developed further in 2016.
Recruitment strategy KI’s recruitment strategy includes coordination and inventory of needs, financing for the group of professors, strategic recruit-
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
ments and recruitment tools as well as a career structure for junior researchers, such as the tenure track. Resources have been allocated for supporting departments in their recruitment of particularly qualified and internationally leading researchers and for “anti-recruiting”. There is also funding for the recruitment of junior researchers (the Career Ladder). An important part of a researcher’s development is to undertake a postdoc period in a highly qualified international environment. This constitutes one of several qualification criteria when filling positions on the Career Ladder.
Commissions as a research team leader Special criteria have been developed for academic commissions at the research team level in order to raise the profile of academic leadership at this level. The research team constitutes the basis of research and is an important part of the department. The research team is an appropriate unit by which to evaluate quality. The commission as a research team leader is also intended to provide the opportunity for development, greater independence and the acquisition of qualifications for career advancement and other leadership commissions.
Research funding Having increased for several years, direct government funding has now levelled off. External funding continues to increase. In relation to 2014, this increase is 8.6 per cent. Funding from research councils has increased by 14.8 per cent, while funding from Swedish companies has increased by 27.3 per cent. The proportion of external funds to government funds has seen a slight increase, to 65 per cent.
31
RESEARCH
The European Union KI retained its position as the largest recipient of EU grants of all Swedish higher education institutions, and one of the largest in Europe, in the field of health. A total of 214 projects at KI were funded by the EU in 2015. Revenues from these amounted to SEK 232 million. KI coordinates twelve of these projects. KI is also involved in projects within the programmes for food, ICT and communication technology, nano-science, safety and environmental science. KI participates in 14 of a total of 57 ongoing Innovative Medicine Initiative (IMI) projects, and is coordinator in one project. KI also commenced two new projects under the EU Health Programme in 2015. The first call for proposals within the European Institute of Innovation & Technology (EIT) Health was announced in 2015. The Scandinavian head office, which is one of six European “Co-Location Centres” has been established in Stockholm at KI Science Park. More about EIT is presented in the chapter Collaboration and innovation. KI maintains its national top position with regard to the number of research constellations within the field of health in “top-down” projects. However, KI has stepped down from first to fourth place in the list of Swedish recipients of EU grants. This is in part due to the fact that Horizon 2020 grants have had a greater focus on applied research.
Number of EU-funded projects at KI in 2015:
214 232
Revenues for EU-funded projects at KI in 2015 amounted to SEK 232 million
European support for individual researchers
Revenue from the EU (including scholarships) 2006–2015 SEK million 300 250 200 150 100 50 0 2006 2007 2008 Income
2009
2010 2011
2012 2013
2014
2015
Scholarships
Due to new accounting principles that were introduced in 2011, scholarship holders are displayed separately above for the years 2011-2015. Source: Agresso.
European grants for individual researchers are primarily received from the European Research Council (ERC) and the Research Executive Agency (REA). Four new projects supported by the ERC were started in 2015. At the end of 2015, KI had 29 ongoing ERC projects. The ERC provides support to individual researchers for ideas that have the potential to make a difference in their particular field. The university has received two Consolidator Grants, which are intended for excellent researchers on their way to consolidating their research position. A grant was also awarded with the aim of advancing ERC project ideas, a Proof of Concept Grant. KI has nine ERC Advanced Grants already running, 14 Starting Grants, five Consolidator Grants and one Proof of Concept Grant. The Marie Skłodowska-Curie Programme encompasses both individual and network-based forms of support, with a common aim to reinforce Europe’s intellectual capital and competitiveness. In 2014 there were 18 individual Marie Skłodowska-Curie grants to researchers at KI. KI had 21 network-based grants, of which six were new. For the first time, KI is the coordinator for such a network project.
Number of EU projects 2011–2015*
Total number of projects with KI as coordinator**
2011
2012
2013
2014
2015
222
234
229
202
214
31
21
19
15
12
* Number of current projects within FP6, FP7 and the Health Programme. Decided but not yet started are not included. ** The figures referring to KI as coordinator do not include projects supported by the European Research Council, ERC. Source: EU database KI.
32
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
RESEARCH
Strategic infrastructure
Photo: Erik Cronberg.
Modern research requires a greater degree of integrated and advanced research infrastructures that can provide researchers with high-quality service. In 2015, KI and the other Swedish higher education institutions have carried out a needs assessment in order to identify advanced methods and expensive instrumentation that could well be hosted at one or more institutions with a nation-wide service. KI is responsible for or participates in several important infrastructures. The Swedish Toxicology Sciences Research Center (Swetox), a centre for research and education in toxicologically related sciences, has undergone further development in 2015. Swetox is a collaboration between eleven universities, with a large research/ testing facility in Södertälje. Science for Life Laboratory, SciLifeLab, has continued its national development and now also includes activities at higher education institutions besides the four hosts, of which KI is one party. SciLifeLab provides access to modern instruments for advanced large-scale research projects, focusing on studies of the function of genes and proteins. SciLifeLab hosts a platform for pharmaceuticals development that shares equipment with the national organisation in the field of chemical biology, Chemical Biology Consortium Sweden (CBCS), at the KI campus. Swedish Infrastructure for Integrated Structural Biology, SWEDSTRUCT, is working to create a cohesive infrastructure
for structural biology and also has synergies with SciLifeLab. Biobanking and Molecular Resource Infrastructure of Sweden (BBMRI.se) aims to create a national standard for the collection of biobank samples, along with cost-effective opportunities for long-term storage and analysis of samples. KI is also working with the Stockholm County Council, SCC, to set up a number of regional facilities for biobanking collaboration. More about infrastructure and business parks is presented in the chapter Collaboration and innovation and in the section Infrastructure.
International Neuroinformatics Coordinating Facility (INCF) INCF was established by the OECD in August 2005 for the purposes of developing the field of neuroinformatics (data sharing and computer modelling). Neuroinformatics is a separate part of bioinformatics, which is very important for the development of knowledge about the function of the nervous system and its psychiatric and neurological diseases. In 2015, Malaysia joined INCF, which now has 18 member countries in Europe, North America, Australia and Asia, and is financed through fees related to the countries’ investments in research and development. INCF also collaborates within various EU projects, such as the Human Brain Project, and the clinical Traumatic Brain Injury Project.
Claudio Brozzoli, research associate at the Aging Research Center (ARC) at the Department of Neurobiology, Care Sciences and Society.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
33
RESEARCH
International co-publications 2013–2015 The number of academic articles published by Karolinska Institutet’s researchers in collaboration with one or more researchers from each country or territory. Certain data included herein are derived from the Web of Science ® prepared by THOMSON REUTERS ®, Inc. (Thomson®), Philadelphia, Pennsylvania, USA: © Copyright THOMSON REUTERS ® 2016. All rights reserved.
3,340
academic articles published by Karolinska Institutet’s researchers in collaboration with researchers in the USA
Internationalisation Internationalisation initiatives at KI aim to improve quality and diversity in our research, education and administration in order to improve both the university’s competitiveness and that of its partners. The concept of internationalisation covers international relations and mobility as well as all activities that add an international dimension. The map shown here is an overview of the international co-publications that KI has had with one or more researchers from each country or territory in 2013–2015.
0 1–10 11–50 51-200 201-1,000 1,000+
TRAC (Vietnam) Training and Research Academic Collaboration (TRAC) is a three-year collaborative project between five Swedish higher education institutions: KI (coordinator), Uppsala University, Umeå University, the University of Gothenburg and Linköping University. These institutions have together received SEK five million from the Foundation for the Internationalisation of Education and Research (STINT) in order to establish a common platform/ common infrastructure for research and education collaboration between Vietnam and Sweden. The project inherits from relations established during the many years that Swedish higher education institutions have been operating in Vietnam.
Mayo Clinic (USA) In September, KI hosted the 21st network meeting within the platform cooperation between KI and Mayo Clinic. Around 140 guests from the USA participated in the hitherto biggest joint conference with a focus on research, education, administration and innovation. Co-arranger for this year’s event was Karolinska University Hospital. During the year funding was admitted for ten research projects and support activities as well as visiting travels.
34
INTERNATIONAL JOINT PUBLICATIONS National University of Singapore and Nanyang2013–2015 Technological University The number of academic articles (Singapore) published by Karolinska Institutet’s researchers in co withmany one or moreKIresearchers each education country or territory. For years has had a from research, and doctoral education partnerships in Singapore. As a means furtherby THOMSON REUTERS ®, Inc. Certain data included herein are derived from the Web of Scienceof ® prepared Philadelphia, Pennsylvania, USA: © Copyright ® 2016. All rights reserved. developing KI’s relationships and inTHOMSON order toREUTERS initiate deeper cooperation within the areas of immunology and infection, a symposium was held at the end of the year with the National University of Singapore, with participation from Nanyang Technological University.
Seoul National University (South Korea) During the year KI renewed its declaration of intent regarding cooperation with Seoul National University. There are research cooperations within several areas, including cancer and biomedical technology.
The Rockefeller University (USA)
The University of Edinburgh (United Kingdom)
KI collaborates with the Rockefeller University through postdoctoral researcher exchanges, short-term exchanges of technical and academic staff and the series of Nicholson Lectures. These lectures are held alternately at each university.
During the year KI and the University of Edinburgh have identified each other as strategic collaboration partners. A Memorandum of Understanding to develop this cooperation within several different complementary research areas, has been signed.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
RESEARCH
830
MACEDONIA
LEBANON
MYANMAR
academic articles published by Karolinska Institutet’s researchers in collaboration with researchers in Australia
BOTSWANA
150
academic articles published by Karolinska Institutet’s researchers in collaboration with researchers in South Africa
NS 2013–2015
Hong Kong (China)
Institutet’s researchers in collaboration In February it was announced that KI had received a donation ry.
of USD 50 million from Hong Kong-based businessman Ming Lau Center for Regenerative Medicine will consist of two nodes, one in Stockholm and one in Hong Kong, where researchers will be given opportunity to work together in an independent international research environment. During the year work has been undertaken to the centre at the Hong Kong Science and Technology Park during 2016.
ared by THOMSON REUTERS ®, Inc. (Thomson®), Wai Lau. The Ming Wai 6. All rights reserved.
Max Planck Society (Germany) During the year KI signed an agreement with the Max Planck Society in Germany to establish a joint laboratory at KI specialising in congenital metabolic diseases: Max Planck Institute for Biology of Ageing – Karolinska Institutet Laboratory. This cooperation will deepen already ongoing research on congenital metabolic diseases.
Makerere University (Uganda) During the year a new agreement has been signed to regulate the opportunity for a double PhD degree. An open seminar and a
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
meeting of alumni were also arranged together with the College of Health Sciences. Four project applications from KI were approved by Sida in 2015 under the Research and Training Partnership Programme 2015–2020.
Muhimbili University of Health and Allied Sciences, MUHAS (Tanzania) During 2015 six project applications with funding by Sida (the Swedish international development agency) have been approved for cooperation with MUHAS in 2015–2020, five of which are coordinated from KI. One of these projects concerns raising the capacity of doctoral education and research at MUHAS.
Equal opportunities Training for research team leaders was carried out for the first time in 2015. The course includes a half-day seminar about equal opportunities and an online course tailored to this group. See also the chapter A university environment in development.
35
COLLABORATION AND INNOVATION
Karolinska Institutet has an important role for society at large
36
Photo: Erik Cronberg.
The traditional Nobel lectures given by the year’s Nobel laureate in Physiology or Medicine attract a large audience to the Aula Medica on the Solna campus. The lectures are given during the Nobel week and are highly appreciated by Karolinska Institutet employees and students and by visitors from the general public.
COLLABORATION AND INNOVATION
Karolinska Institutet, KI, collaborates extensively with other higher education institutions, hospitals, government agencies, companies and organisations throughout the world. Such collaborations are essential to a successful university. The vast majority of KI’s research is carried out in collaboration with an external party, and more than half together with an international party. KI’s single largest partner, Stockholm County Council (SCC), facilitates vitally important clinical research and education. More than half of KI’s activities are conducted in the clinical environment, primarily in hospitals, but also in primary care and elderly care facilities. The areas around KI’s campuses in Solna and Huddinge are constantly being developed as strong nodes for medicine and health research. KI shares its location with Karolinska University Hospital, KI Science Park, SciLifeLab, the Public Health Agency of Sweden and the European Centre for Disease Prevention and Control, ECDC. Stockholm University, Södertörn University, the Royal Institute of Technology, KTH, and the Stockholm School of Economics are the closest academic institutions in Stockholm that KI collaborates with. In 2015, KI and KTH implemented a joint education programme and doctorate degree in medical technology. Eleven universities are behind the initiative at the national academic centre of excellence, Swetox in Södertälje, with research, education and broad collaboration in toxicology. In 2015 Swetox became the first academic research environment in Sweden to be granted GLP status (The OECD Principles of Good Laboratory Practice) for Toxicological studies, Analytic and Clinical Chemistry. In the region we also have close collaboration with Uppsala University, several companies and foundations, including Flemingsberg Science and Stockholm Science City. The latter two are supported by KI with operating grants of SEK 1 million and SEK 500,000 each per year. In cooperation with the Max Planck Gesellschaft in Germany and its Institute for Biology of Ageing, a Max Planck laboratory has been established at KI with activities specialising in rare congenital metabolic diseases.
More than half of the research is carried out together with an international party
MAX PLANCK INSTITUTE FOR BIOLOGY OF AGEING – KAROLINSKA INSTITUTET LABORATORY
Collaboration with Stockholm County Council SCC is KI’s single most important partner; a considerable portion of KI’s research and education requires access to the healthcare services. Extensive restructuring of healthcare in the Stockholm region requires intensified collaboration between KI and the county council and this takes place at different organisational levels. Under the KI-SCC collaboration organisation, KI is participating in the planning and operationalisation of the new Karolinska University Hospital and in the designing of the new operational model at the University Hospital. In addition to this, KI continues its involvement in the joint KI-SCC project Programme 4D and in the establishment of an academic specialist centre. Another important focus area is ICT-related development. KI is represented in the county council’s RSIT (regional colla-
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Innovations
37
Photo: Erik Cronberg.
COLLABORATION AND INNOVATION
Last-minute preparations for the 2015 Nobel lectures given by the Nobel – laureates in Physiology or Medicine, William C. Campbell, Satoshi Omura and Youyou Tu.
boration IT) and has been invited to participate in working groups concerning the county council’s Programme 3R initiative for the future healthcare information environment.
New regional ALF agreement In November 2015, KI and SCC signed a new regional agreement concerning cooperation on clinical research and training and the development of health care to enter into force on 1 January 2016. It replaces, among other things, the time-limited regional ALF agreement between KI and the county council that was signed in April 2015. With the new agreement, the parties will work together to promote advances in healthcare by deepening and expanding cooperation in the areas of translational and clinical research, education, development and innovation. A joint, long-term strategy for collaboration on university healthcare in the Stockholm region will be drafted and a new collaboration organisation will be established in 2016.
Collaboration for the allocation of RDE resources Collaboration for the allocation of ALF funds and the RDE (research, development and education) resources that the county council brings to the cooperation for joint prioritisation is organised within the KI-SCC collaboration organisation. KI-SCC annually announces funds for various activities including clinically focused medical research and development projects and funds for clinical positions at various levels, such as clinical post-doctoral researchers and clinical researchers. In addition to resources for activities at appropriate units, funds
38
are also distributed to clinical research schools and core facilities, i.e. service units that offer services that cannot easily be implemented and/or carried out by individual research teams. The bulk of resources earmarked for education are used for placements within the medicine programme and the speech therapy programme. Funds are also allocated to, e.g. adjunct clinical lecturers, pedagogical research and development projects and to the activities of KUA, KUM and KTC (clinical education ward, clinical education reception and clinical training centre). In the area of infrastructure, KI-SCC has continued to support the Stockholm Medical Biobank and the Quality Register Centre Stockholm. There is more about clinical research and education in the respective chapters.
Collaboration with the general public KI works purposefully to inform society at large about the knowledge being created at the university. The mass media is an important channel for the dissemination of research results to the university’s external target groups and a wider general audience. KI’s popular science magazine, Medical Science, is distributed to the press, politicians, funders, hospitals and schools and to paying subscribers and purchasers of individual issues. Last year, the magazine increased its printed edition to 25,500 copies and it is also available on several digital magazine sites. An annual collection edition in English is distributed to groups such as foreign journalists and embassies.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
341 SEK million in funding from companies in 2015
Photo: Gustav Mårtensson.
COLLABORATION AND INNOVATION
In 2015 Vice-Chancellor Anders Hamsten and Peter Kurtzhals, research director at Novo Nordisk A/S, signed a collaboration agreement on diabetes research.
Many of KI’s researchers and teachers are also involved in public debate as the authors of opinion pieces and books, as lecturers and by participating in fairs and conferences. During the year both researchers and students at KI have also started podcasts with the general public in mind. Since 2001, KI has had close cooperation with several upper-secondary schools, primarily in Stockholm’s outer areas. The aim is to increase the interest of school pupils in the natural sciences, to encourage them to pursue further studies and to broaden the recruitment base. The focus is on programmes in natural sciences or engineering.
Innovation support and collaboration with industry A significant proportion of the research at KI is carried out in close collaboration with companies, both Swedish and foreign. This allows for an exchange of knowledge and also provides a source of funding. Over the course of 2015, KI received SEK 341 million in funding from companies (SEK 289 the previous year), of which SEK 89 million came from companies based abroad. The development work for collaboration and innovation is based on the knowledge triangle – research, education and innovation – with the entrepreneur at the centre. Joint cooperation forms and objectives are produced in order to optimise results and effects in the form of benefits for customers and society at large. Making this possible requires robust steering, monitoring and follow-up, for example through the following initiatives: • An Advisory Council has been established with representatives from KI, SCC, the Stockholm County Administrative Board, private companies and investors. • New steering with a clearer division of roles and integration of KI’s various innovation actors is planned. • New forms of collaboration with industry have been analysed and are being applied successively. KI Science Park and several important centres for collaboration are based at KI. SciLifeLab, which is a national resource in
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
molecular bio-sciences, is operated jointly by KI, KTH, Uppsala University and Stockholm University and is funded by government appropriations and funds from the Knut and Alice Wallenberg Foundation and AstraZeneca. A new centre, ICMC, for translational research in collaboration with AstraZeneca was inaugurated in 2015. The centre’s overall objective is to identify and validate new target molecules in the area of cardiovascular and metabolic diseases. In February 2015, KI and the Danish pharmaceutical company Novo Nordisk A/S signed a collaboration agreement on diabetes research. The research programme will run for five years and will mainly be undertaken at KI, with some periods at Novo Nordisk in Denmark. Another example of long-term company partnerships established in 2015 is Johnson & Johnson Innovation, which intends to enhance KI’s innovative strength and to convert this into product and business development and into implementation within healthcare. At the same time KI also commenced a partnership with the pharmaceutical company Janssen (part of Johnson & Johnson). This project uses healthcare data to analyse the follow-up of disease and treatment and how this relates to effects in clinical trials. An important project based on the knowledge triangle is EIT Health, which is a Knowledge and Innovation Community, KIC, for Healthy Living and Active Aging. This KIC was established by the European Institute for Innovation and Technology, EIT, in 2014. EIT Health is one of the EU’s biggest innovation and education initiatives in the field of health and will be financed by up to EUR 700 million until 2020. KI participates in EIT Health in order to partner with prominent Swedish and European institutions and companies to address the challenges of demographic change. In 2015 the legal and financial structures for EIT Health have been established. The Scandinavian head office, which is one of six European Co-Location Centres has been established in Stockholm at KI Science Park. For more information on collaborative research projects, see the chapter Research and the table appendix – Table 6, Revenue 2015, largest sources of funding.
39
COLLABORATION AND INNOVATION
Karolinska Institutet
Karolinska Institutet Holding AB
Overarching tasks of the innovation system
The Innovation Office
Karolinska Institutet Innovations AB
• Inspire new innovative ideas
Support for private sector collaboration, regional collaboration, information and guidance for researchers in innovation issues
Unit for Bioentrepreneurship Research and education in innovation and entrepreneurship
Incubator. Business evaluation and support for commercialisation. Start-up formation and coaching. Licensing.
• Support the development of ideas towards utilisation • Identify business opportunities with innovative potential • Secure “proof of concept” and funding in an early phase
Karolinska Institutet Science Park AB
• Promote commercialisation with customer benefit
Soft and hard infrastructure, meeting places for knowledge transfer and experience exchange, specific support functions for life science companies
• Establish partnerships with industry and investors
Academia
Incubator
KI’s integrated innovation system with clear roles within the university for innovation education, research, early-phase advice and support for private sector collaboration. KI Holding AB offers support for commercialisation of ideas and infrastructure for companies.
The innovation system Companies, researchers or students who wish to collaborate with industry and other organisations outside academia or develop innovative ideas, whether they can be commercialised or otherwise, are offered the concrete support initiatives of KI’s innovation system. The objective is to stimulate the utilisation of sciencebased knowledge in medicine and health, such as new products or services. The innovation system strengthens translational capability and contributes to a more professional interaction between academic research and education and society at large with a focus on industrial enterprise and utilisation.
Early-stage advisory and cooperation with industry KI has run an innovation office since 2010. The innovation office provides comprehensive and integrated service aimed at researchers, students and companies. In 2015 there were 97 early-stage advisory cases handled at the innovation office, seven of which involved advice to students. Of these cases, 30 have been followed up with various types of in-depth initiatives, of which 22 led to extended patent investigations. Six advice cases have been passed on to KI Innovations in order to obtain Verification for Growth funding from Vinnova. There were 17 cases of company collaboration with already established research at KI during the year involving both large and small companies, of which five cases led to more concrete collaboration and/or an agreement. The Innovation Office participates in several regional and national projects that aim to improve conditions for the utilisation of ideas and knowledge, including several projects funded by Vinnova. With support from regional structural funds, the Innovation Office has collaborated with SCC in order to further enhance the
40
growth opportunities of small companies in the region. In cooperation with Södertörn University, KI has established a multidisciplinary meeting place for academia, industry and society at large.
KI’s incubator Karolinska Institutet Innovations AB offers commercial advice and support. Ideas and inventions based on research, primarily from researchers at KI, are evaluated. KI Innovations is responsible for allocating funding from Vinnova to evaluate the commercial potential of promising projects. In 2015 KI Innovations examined, assessed and followed up 66 ideas and inventions. Of the 66 ideas submitted, 31 have progressed to verification by external experts financed by Verification for Growth (Vinnova), pre-study funding (ALMI) or utilisation funding (Swedish Foundation for Strategic Research, SSF). During the year four new companies/projects have been brought into the incubator at KI Innovations. Of the projects or companies undergoing verification at KI Innovations, ten have successfully secured external funding (investment or other form of support) during the year. One project with significant ownership by KI Innovations made a successful exit during the year through the sale of rights to a patented technology platform. At the end of 2015, there were 55 active commercial projects at KI Innovations. More than 1,500 ideas and inventions have been evaluated since the company was founded in 1996.
KI Science Park KI Science Park offers premises in a business development environment on the Solna and Huddinge campuses. KI Science Park has 86 companies (of which nine listed companies) with 672 employees and emerged from KI’s research, healthcare and other companies which chose to localise close to KI. The park acts as a growth and meeting place for the companies and their stakeholders. In order
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
COLLABORATION AND INNOVATION
Selected key indicators for collaboration
2011
2012
2013
2014
2015
A. Externally financed research, total (SEK million) – from companies, total revenue (SEK million) – from overseas companies (SEK million)
2,792 250 79
2,935 241 73
3,040 268 85
3,202 292 94
3,478 341 89
422 129
395 124
291 131
251 110
248 105
69 17
63 14
56 8
69 11
74 8
235
250
241
304
279
71 51
75 56
84 64
85 67
91 71
B. Contract research (SEK million) – from companies, total revenue (SEK million) C. Contract education, total revenue (SEK million) – from companies, total (SEK million) D. Contract education (FTE students) E. Adjunct Professors (total number) – of which are financed by Stockholm County Council F. Doctoral students employed in the private sector and public organisations (annual working units)
446
455
479
500
511
G. Number of EU projects (FP6, FP7, H2020 and EU health programme) – as coordinator
222 31
234 21
229 19
202 15
214 12
H. Ideas/advice/cases treated at KI Innovations AB and the Innovation Office
157
178
123
139
150
I. KI Innovations AB active projects at turn of year
13
11
30
50
55
J. Companies within KI Science Park
65
63
70
82
86 672
580
420
575
635
L. Scientific articles, percentage co-published with parties outside of KI (%)
K. Employed by companies within KI Science Park
84
83
85
84
M. Scientific articles, percentage co-published with international parties (%)
62
63
63
63
Sources: A–C: The financial system Agresso, D: The student database Ladok, E: KI Recruitment Unit, F: The student database Ladok, G: KI Grants Office, H–K: Data from respective operations, L, M: Web of Science/KI University Library. Certain data included herein are derived from the Web of Science® prepared by THOMSON REUTERS®, Inc. (Thomson®), Philadelphia, Pennsylvania, USA: © Copyright THOMSON REUTERS® 2016. All rights reserved.
84 %
of academic articles were published together with an external party
672 employed by companies within KI Science Park
91
adjunct professors
to support the companies’ development, KI Science Park offers a medicine and life science focused mentor programme, seminars, workshops and a business development programme.
Research in innovation and entrepreneurship at KI aims to increase the level of knowledge and the development of innovation systems and innovation processes in medicine and life science.
Education and research in innovation and entrepreneurship
KI Holding AB
The Unit for BioEntrepreneurship (UBE) is an academic unit at KI that conducts research in innovation and entrepreneurship, knowledge dissemination and education, including a two-year international Master’s programme given at KI. In 2015 almost 300 students at KI received education in entrepreneurship and innovation. A significant proportion of this research and education takes place in collaboration with companies and organisations – through a total of 56 different collaborative projects in 2015. Interdisciplinary studies are facilitated at the Stockholm School of Entrepreneurship, an academic collaboration between KI, the Stockholm School of Economics, KTH, the University College of Arts, Crafts and Design, and Stockholm University. In 2015 a one-year project was carried out to initiate implementation of entrepreneurship in KI’s doctoral education.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Karolinska Institutet Holding AB owns, sells and manages shares and participations in several project and service companies. Their aim is the commercial exploitation of projects and knowledge developed or originating from activities at KI so that knowledge and research results are put to good use. KI Holding controls six wholly owned subsidiaries: KI Innovations AB, KI Science Park AB, KI Housing AB, KI University Press AB, the recently activated KI Information AB and the dormant KI Support AB. KI Holding is by voting power (25.6 per cent) the largest owner and in equity (6.8 per cent) the third largest owner of the independent investment company Karolinska Development AB (Nasdaq Stockholm: KDEV, KD). As of 31 December 2015, its portfolio consisted of twelve companies. In December 2015, KI Holding and KD signed a new nonexclusive deal flow agreement.
41
A university environment in development
Karolinska Institutet is building a university environment for the future
42
Photo: Erik Cronberg.
Steinar Stokke (CEO, SveaNor), Kerstin Tham (Pro-Vice-Chancellor at KI) and Daniel Dronjak (Chair of the Executive Committee, Huddinge) cutting the turf for the new research building on the Huddinge campus. Neo is expected to be ready for occupancy in late 2017.
A university environment in development
A university environment in development During the year, good career and development opportunities, a good work environment and a committed leadership that encourages development have been key concepts in Karolinska Institutet’s (KI’s) work to promote an attractive workplace. All these factors constitute fundamental conditions for enabling KI to develop and strengthen its position as one of the world’s leading medical universities.
In 2015 KI has continued its work to meet the HR challenges described in Strategy 2018, which include the development of leadership, employeeship, the work environment and recruitment. As regards overall competence at the university there will be a need for both specialised and broad skills with a clear focus on quality. Strategic recruitments of the most skilled employees in international competition are important for enabling KI to strengthen its competitiveness as an internationally successful university. Equally important is the provision of optimal conditions for both senior and junior employees to enjoy and develop in their work. It is not sufficient to offer good career and development opportunities and good employment conditions; we must also offer a good work environment and a committed leadership that encourages development. Employees should feel pride, motivation and commitment in their work and should want to recommend KI as a workplace. Based on the objectives established in Strategy 2018, several measures in employee empowerment have been planned, commenced or implemented in 2015.
Human resources report In October 2015, KI had 5,233 employees, corresponding to 4,694 full-time equivalent (FTE) employees*. This is an increase of 5 per cent on the same period in 2014. 60 per cent of employees (3,163 persons) were women. All staff categories increased with the exception of preclinical senior lecturers (-11 per cent) and lecturers (-1 per cent). During the year KI decided to discontinue doctoral grants as a form of funding doctoral education from July 2016. However, a gradual transition already began in 2015 and doctoral studentships as a form of funding increased by 18 per cent.
Photos: Erik Cronberg.
An attractive workplace in which to develop
5,233 EMPLOYEES
3,163 ARE WOMEN
* Here, “full-time equivalent employees” refers to the number of full-time and part-time employees translated into full-time employees. A person employed on a half-time basis is counted as 0.5 full-time equivalents.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
43
A university environment in development
The human resources report only covers employees with a formal position. KI’s activities also involve a large number of persons who are affiliated with KI. Staff turnover is largely unchanged compared with 2014, i.e. 11 per cent for permanently employed staff and 20 per cent in total for both permanent and temporary staff, including doctoral students.
is within the interval 40–60 per cent for senior lecturers, senior researchers, assistant professors, postdocs and doctoral students. Among professors, the proportion of women has increased compared with 2014, i.e. 29 per cent of professors are women. Among technical/administrative positions, a large majority is still women, but the gender distribution has become somewhat more even, from 72 per cent women in 2014 to 70 per cent women in 2015.
Newly employed professors and senior lecturers
Teachers with doctorates
During the year KI employed 16 new professors, including nine women, having advertised these positions in international competition. Two council researchers, of which one is a woman, have been employed as professors following an assessment of qualifications. KI has also recruited five internationally prominent and successful professors, of which one is a woman, through nomination. During the year the university has recruited 16 new visiting professors, including 7 women, and 21 people have been newly employed or had employment periods extended as adjunct professor, of which 6 were women. In October 2015, the combined level of employment for the adjunct professors was equivalent to just under 21 FTEs. During the year, 13 people have been employed as senior lecturers, of which 11 were women, and 14 people have been newly employed or had employment periods extended as adjunct senior lecturer, of which 3 were women. In October 2015 all adjunct senior lecturers employed corresponded to around 9 FTEs.
The number and proportion of teachers with doctorates continues to increase, from 88 per cent in 2014 to 91 per cent in 2015. The human resources report for teachers with doctorates includes professors, senior lecturers, assistant professors and lecturers. Only the group of lecturers has teachers without doctorates.
Number of teachers with doctorates and proportion of all teachers 2012–2015 (FTE employees) Number of doctorates
Proportion of total (%)
2012
714
84
2013
717
87
2014
739
88
2015
776
91
Year (%)
Staff gender distribution Gender distribution is slightly evened, but remains at approximately two-thirds women. As last year, the gender distribution
Source: Primula.
FTE employees, various categories of staff 2012–2015 2012
2013
2014
Change 2014–2015 (%)
2015
Number
Women (%)
Number
Women (%)
Number
Women (%)
Number
Women (%)
Professor, pre-clinical
214
29
221
28
221
28
230
29
4
Professor, clinical
153
24
151
27
146
27
143
28
-2
Senior lecturer, pre-clinical
122
62
109
64
110
62
110
63
0
37
41
41
47
48
51
45
46
-5
Lecturer
159
75
155
73
159
75
157
75
-1
Researcher
364
45
345
47
360
46
379
48
5
Research associate
161
51
149
53
161
52
170
53
5
Postdoctor with employment
429
60
493
56
526
56
539
57
2
Senior lecturer, clinical
Doctoral student
572
64
595
64
650
59
770
58
18
Technical and admin. staff
1 981
75
2 023
74
2 093
72
2 153
70
3
Total
4,192
64
4,283
63
4,473
62
4,694
61
5
Here, “full-time equivalent employees” refers to the number of full-time and part-time employees translated into full-time employees. The figures above include all employees who were not on a full leave of absence during the month measured, regardless of full-time/part-time or length of their employment, but exclude those in assistant posts in combination with doctoral grants and adjunct teachers. The figures refer to October 2015. Source: Primula.
44
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
A university environment in development
Gender distribution in various staff categories Professor = 372 Senior Lecturer = 155 Lecturer = 157 Senior researcher = 379 Assistant professor = 170 Postdoctor with employment = 539 Doctoral student = 770 Administrative staff = 1,048 Technical staff = 1,105
800
600
400
200
0
200
Women (total 2,857)
400
600
800
Men (total 1,837)
Source: Primula.
Newly appointed professors and lecturers 2012–2015 2012
2013
2014
2015
Number
Women (%)
Number
Women (%)
Number
Women (%)
Number
Women (%)
Professors 24
33
23
26
19
36
23
48
Visiting professors
Professors*
3
0
3
0
8
25
16
44
Adjunct professors
9
44
13
38
13
46
10
30
36
33
39
28
40
37
49
43
19
47
12
100
17
64
13
62
5
40
5
60
6
0
5
20
24
46
17
88
23
47
18
50
Total Senior lecturers Senior lecturers* Adjunct senior lecturers Total
*Promoted professors are included for 2012-2013. **Promoted senior lecturers are included for 2012-2013. Source: Access, internal KI-database for recruitment.
Recruitment The recruitment strategy group The university management’s Strategy 2018 has focused on raising quality in all parts of KI’s operations. The management has selected a few strategy areas where it proposes general measures to be taken. The strategy area for employees covers initiatives related to the recruitment and career of researching and teaching staff. In March 2015, KI appointed an inter-board working group to produce proposals for a recruitment strategy for KI.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Strategic recruitment For the second consecutive year KI announced positions for the recruitment of prominent junior researchers within medical science. This is a strategic investment in junior researchers with particularly excellent academic qualifications and future potential. It is a broad investment focusing on both basic research and clinical research. The investment covers three levels of the academic career; research associate, extension of previous employment as a research associate, and researcher. The Board of Research finances the successful applicant’s salary for four, two and five years, respectively. This year’s announcement drew a total of more than 500 applicants.
45
A university environment in development
KI starts research activities in Hong Kong
New courses
In connection with KI’s start of research activities in Hong Kong, work has commenced in 2015 to investigate the conditions for acting as an employer in Hong Kong. This has, for example, involved studying Hong Kong’s labour law and mapping employment conditions and benefits that are applicable to researchers, especially at universities. The current establishment of activities in Hong Kong is intended to serve as a model for similar initiatives in the future.
In addition to the 15 basic work environment courses that are regularly given to managers, safety representatives and others dealing with work environment issues, KI has in the past year developed specialised courses. Four courses specialising in the risk assessments made in systematic work environment management and one course on the role of safety representatives in new construction and renovation have been offered. September 2015 saw the start of new leadership training for research team leaders that includes a module on laboratory safety.
International Staff Service Intensified international recruitment has raised demands on information and support regarding international relocation. In 2015 activities for the reception of international personnel have been enhanced and now also cover a supplementary service for research associates, researchers, senior lecturers and professors. The service supports with personal consultation on relocation matters, for example accommodation, schooling healthcare, banking and taxes.
Leadership and professional development Provision of expertise and leadership development By means of a thorough needs analysis performed through consultation with all departments, KI has during the year designed an overall concept for provision of expertise and leadership development (Talent Management @KI). This includes training and developing employees and leaders/managers to create an effective process for career switching and phase-out. KI has also carried out individual development initiatives for managers and leaders and has supported the organisation through tailored development initiatives for specific professional functions and teams. Introduced this year is participation in mentoring programmes through the network of Stockholm’s higher education institutions. The basic range of managerial training now includes a new course for research team leaders. Courses in English have increased in 2015. Furthermore, work to introduce a leadership development programme for senior managers has been started.
Work environment and employment conditions Code of Conduct KI’s guidelines for work environment and health include the objective for the working climate to be characterised by job satisfaction and community, open communication with a permissive attitude and approach, respect and consideration, and collaboration, participation and influence. In order to strengthen and clarify this, spring 2015 saw the introduction of a Code of Conduct that covers all employees, i.e. also scholarship holders and affiliated co-workers.
46
New training facilities and meeting place for employees and students On 7 October 2015, KI inaugurated its training facilities for employees and students on the Huddinge campus. The facilities are unique in their design, which has prioritised large areas and space for movement and social interaction. The idea is that these areas will primarily inspire functionality, the joy of motion, learning and application in everyday life, but also have a function in teaching. Furthermore, instructors and team leaders, mainly from KI, have been recruited to create a safe and welcoming atmosphere for all visitors.
Interventions and health promotion for students In accordance with the programme proposal adopted last year, KI has increased resources for also being able to offer students access to premises, events and training classes. As part of its health promotion initiatives, KI has started several new training classes and opened new premises, described above. Interventions linked to the results from the employee survey have also been implemented during the year. Among other things, the university has offered courses in English on support for sleep and stress-related problems.
Equal opportunities KI’s activities on equal opportunities are based on the equal rights and opportunities of all employees and students – regardless of gender, gender identity and expression, ethnicity, religion or other faith, disability, sexual orientation or age. The Board and the ViceChancellor are ultimately responsible for these efforts being target oriented in accordance with discrimination legislation. The Council for Equal Opportunities, reporting directly to the ViceChancellor, works strategically at an overall level and supports work at the local level (departments and study programmes, etc.). The work is rooted in KI’s action plan for equal treatment, which covers all employees as well as applicants and students at all levels.
Recruitment targets for professors The proportion of women among newly appointed professors and visiting professors during the year was 45 per cent, compared with 35 per cent last year. During the entire recruitment period 2012-2015, the proportion of women among newly appointed professors and visiting professors was 36 per cent. In KI’s appropriation directions for the fiscal year 2012, the Ministry of Education and Research established a recruitment
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Foto: Gustav Mårtensson.
A university environment in development
KI’s recruitment strategy includes coordination and inventory of needs, strategic recruitments and recruitment tools as well as a career structure for junior researchers.
goal for the university stating that at least 47 per cent of the professors employed during the period 2012-2015 should be women. The recruitment goal does not include adjunct professors. To achieve this goal, an action plan was drafted in 2013. The action plan includes financial support for departments which employ a woman as professor or visiting professor, quality assurance of the recruitment process, special KID-funding (partial financing funds for doctoral studentship) for women supervisors and skills enhancement programmes. As a part of the latter initiative, recruitment staff and academic representatives with a recruitment task have been offered training in gender equal recruitment during the year. Since 2014 financial support has been allocated to eight departments to employ a woman as visiting professor and funding for thirteen departments to employ a woman as professor. The initiative has been successful and the Board of Research has therefore decided to let it continue until mid-2016.
Courses and seminars Equal opportunities has been an integrated part of courses, seminars and other skills enhancement programmes for students/ doctoral students and for managers and other employees. Among
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
the recurrent events offering training sessions in the area of equal opportunities are the course within formal management and leadership and courses for research team leaders and supervisors. In addition, a seminar on the discrimination ground of religion or other faith was arranged for the departments’ HR personnel and KI’s representatives for equal opportunities, with around 40 participants.
Funds for preventive efforts in the area of equal opportunities In order to stimulate preventive work and good ideas in the area of equal opportunities in departments and study programmes, the KI Council for Equal Opportunities offers financial funding for longer projects and occasional events specialising in one or more of the statutory grounds of discrimination. In 2015 funding has been allocated to KI University Library for a new book collection to supplement the library’s regular literature. The aim of this collection is to particularly highlight norm-critical and intersectional perspectives in areas such as medicine, pedagogy and psychology, to visualise perspectives that are often surpressed or stereotyped and to create conditions for an inquiring and critical examination of one’s own patterns of thought and actions.
47
A university environment in development
Infrastructure
The property owner, Akademiska Hus, is investing approximately SEK 3.2 billion, and Karolinska Institutet has signed a 25-year lease. The cost development is under control and the forecasted rental cost is only a few per cent above what was budgeted in June 2012. Five departments on the Solna campus will move into Biomedicum, and most of the buildings that they use today will be vacated by KI and leased out by Akademiska Hus to other operations. In 2015–2016, the Wargentin building is undergoing various stages of adaption for the KI Biobank. During the year, an assessment concerning the conversion and extension of the Wargentin building was also initiated in order to create grouped premises for electron microscopy in close proximity to Biomedicum. There are also plans for improved and expanded research premises in Huddinge. These plans concern the new research building Neo and the Future Laboratory project. In June 2015, a lease was signed for just over 15,000 square metres in Neo (80 per cent of the building), and construction was started with estimated completion in late 2017. The main purpose of Neo is to bring together activities in modern medical research premises in immediate proximity to Karolinska University Hospital so as to facilitate translational research which in the relatively near future can be converted into healthcare and treatment methods. In addition to research facilities, rooms for teaching, conferences and examinations are also being planned in Neo. Parallel to Neo is the Future Laboratory project, which will completely renovate about 10,000 square metres on several floors in existing premises. The goal is to create modern facilities for research and education that will lead to increased interaction and collaboration between departments and clinics. It is planned that Future Laboratory will be ready for occupancy in stages during 2017 and 2018. In collaboration with Akademiska Hus, the KI Facilities Office is monitoring the location and design of the egress from the new Metro line with a station at Solnavägen between Karolinska University Hospital and KI. Metro traffic is estimated to begin around 2022. The work on a detailed development plan for housing in the northern part of the Solna campus has been further delayed due to repeated appeals. The matter has passed the Stockholm County Administrative Board, but is now being appealed at the Land and
48
Photo: Erik Cronberg.
As last year, 2015 has been characterised by the planning of the major investments in premises under Strategy 2018. The single largest investment is the construction of Biomedicum and the adjoining building for comparative medicine (KM-B) on the Solna campus. During the year both buildings have grown to full height, even though a lot work remains until completion and occupancy in 2018. The area of the premises will be a total of approximately 55,000 square metres with space for just over 1,600 employees.
The project Future Learning Environments is based on teaching and learning research, with the goal of ensuring that learning environments at Karolinska Institutet’s campuses will create the best possible conditions for education of the highest quality.
Area and costs of premises 2011–2015 Area (sq.m.)
Cost (SEK million)
Proportion of total cost (%)
2011
200,859
586
11
2012
213,881
667
12
2013
218,870
741
13
2014
220,628
763
13
2015
220,759
754
12
Year (%)
Costs for premises include rent, electricity, media, cleaning etc. Source: KI real estate system and Agresso.
Environment Court. Occupancy in 2016 is no longer possible but can take place no earlier than late 2017. The intention is for KI to pre-lease all 400 planned apartments and mediate these to visiting research fellows and students via KI Housing. During the year, a new health promotion centre was completed on the Huddinge campus. In autumn 2015, 1,100 square metres became available to students and staff for various forms of strength and motion training. The renewal of KI’s learning environments – lecture halls and seminar rooms as well as more informal settings – continued in 2015, mainly in Huddinge. Here, the concept has been taken to a new level in highly creative environments that have been well received by students.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
A university environment in development
Sustainable development Karolinska Institutet’s, KI’s, vision is to significantly contribute to the improvement of human health. Good public health is both a prerequisite and a goal for sustainable development. In addition, KI contributes to sustainable development by taking environmental and social responsibility in its daily activities. A large part of the university’s sustainability work is carried out within the framework of KI’s environmental and sustainability management system, which aims at meeting the requirements of the international standard ISO 14001.
Research and education for sustainable development In accordance with Strategy 2018, KI’s activities are to be characterised by a strong social commitment and contribute to sustainable development within and outside Sweden’s borders through our education and research. In 2015 KI made efforts to increase knowledge and awareness of sustainable development among the general public, students, researchers and teachers. The results from an online survey about sustainable development, addressed to KI’s doctoral course directors, have been compiled in a report presenting good examples and other subject areas in which doctoral programmes can further clarify the aspect of sustainable development. During the year an interprofessional elective course, Sustainable development in healthcare, was offered to second-cycle students, and the number of students admitted has doubled in comparison with the previous year. Sustainability issues have also been clarified on the university’s web portal for the environment and sustainable development.
various needs. Training in this area can be obtained from the University Administration as necessary. The virtualisation project at the central IT Office at KI is more or less completed. In its next stage KI will endeavour to offer the KI departments the opportunity to replace their traditional data servers with virtual servers in the the central IT Office’s system. The university will thereby raise the security of the IT environment at the departments, reduce electricity consumption and reduce the use of old equipment. The standard workplace project has also been implemented centrally at the University Administration and will be offered to the departments. The project will make it possible to purchase from a selection of “green” standard computers that are configured as environmentally efficiently as possible. Other important contributions are the environmental activities at the departments, for example aiming at reducing the amount of hazardous substances used in laboratories. The role of environmental and sustainability representative has been formalised during the year and is now included in an appendix to the Vice-Chancellor’s decision-making procedures and delegation rules for Karolinska Institutet. Environmental and sustainability representatives are now appointed at the departments through delegation by Heads of Department, and training for them has been implemented during 2015. In order to improve chemicals management with respect to the environment, work environment and safety, chemicals representatives have also been appointed at the departments through delegation by Heads of Department. Training, activities and meetings have been initiated. Chemicals inventory takers for each research team have similarly been appointed. During the year a KI-adapted course has also been designed and offered to acting supervisors and deputy supervisors for flammable goods. In 2015 the bar code system of the KLARA product database has been implemented at KI and training has been carried out. The bar code system can be used for chemicals inventory and management and has been introduced in order to increase safety and to reduce the quantity of hazardous chemicals at Karolinska Institutet.
Sustainable campus
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
During the year, environment and sustainability representatives, chemicals representatives and chemicals inventory takers have been appointed at the departments. Photo: iStock.
In accordance with Strategy 2018, KI’s activities are to be characterised by care for the internal and external environments. In 2015, KI completed several projects and measures to promote the environment and sustainable development. A selection of these is presented below. KI has an objective to reduce the climate influence of travelling. One means is the commuter bus that has been running exclusively on renewable fuel between Solna and Huddinge since 1 September 2015 by agreement between KI and Karolinska University Hospital. An electric car has been purchased for catering on the Solna campus. The electric car has symbolic value as it is a small step on the path towards a fossil-free fleet of vehicles and reduces climate influence, noise and particle emissions on campus. In order to reduce the need for travelling there are various solutions for virtual meetings that are being gradually developed/ supplemented, in order to follow developments and to cover
49
FINANCIAL REPORT
Karolinska Institutet’s finances provide conditions for prominent research and education
50
Photo: Erik Cronberg.
Deputy Head of Department Margarita Diez, Head of Administration Karin Wallin Blomberg and Head of Department Jan Hillert discuss financial issues at the Department of Clinical Neuroscience, Solna campus.
FINANCIAL REPORT
6.5 KI:s turnover in 2015
SEK billion
Karolinska Institutet’s (KI) finances remain strong. In 2015 turnover, measured in revenues, increased by SEK 318 million or 5.2 per cent compared with 2014. The largest increase in revenues is in the category of external grants, SEK 269.4 million compared with 2014. Research activity is still dominant and amounts to approximately 84 per cent of the total turnover. The positive change in capital for the year amounted to a total of SEK 75.9 million (SEK 62.7 million), of which KI activities accounted for SEK 80.4 million (SEK 78.3 million) and Karolinska Institutet Holding AB accounted for minus SEK 4.5 million (minus SEK 15.7 million).
Sources of funding The funding of KI’s activities in 2015, divided into sources of funding, as shown in the pie chart on the right. There is a decrease in the category of direct government funding from 45 to 43 per cent, while research councils and other government agencies increased by the corresponding percentage. The percentages for the other sources are unchanged between the years. The largest individual sources of external funding are listed in the table appendix, Table 6. The combined government funding of KI’s activities amounts to 64 per cent, which is at the same level as in 2014.
Karolinska Institutet’s revenue for 2015, SEK 6,475 million in total (SEK 6,156 million)
1% 4% 1% 7%
16 %
43 %
7% 6% 15 % Direct government funding 43 % (45 %) Research councils 15 % (14 %) Other government agencies 6 % (5 %) Municipalities and county councils 7 % (7 %) Swedish foundations and organisations 16 % (16 %) Foreign foundations and organisations 7 % (7 %) Swedish companies 4 % (4 %) Foreign companies 1 % (1 %) Financial income 1 % (1 %)
The source of information in this chapter is the financial system Agresso, unless otherwise specified. Last year’s figures in brackets.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
51
FINANCIAL REPORT
Education at bachelor’s and master’s level
Bachelor’s and Master’s education total SEK million 2012
2013
2014
2015
Revenue Direct goverment funding
833.1
874.8
870.6
906.4
Fees and other remunerations
100.6
97.3
118.0
123.9
19.8
18.9
18.5
19.8
0.0
0.0
0.0
0.0
Grants Financial income Total revenue
953.6
991.0 1,007.1 1,050.1
Staff costs
507.7
483.4
559.9
551.2
Premises costs
109.2
100.4
121.9
90.8
Other operating expenses
335.7
350.3
340.1
373.6
Financial costs
0.1
0.1
0.1
0.2
Depreciation
12.2
15.7
7.8
14.0
Expenses
Total expenses
965.0
949.9 1,029.9 1,029.8
Transfers Government funding
7.6
7.6
4.5
4.5
Funding from other government agencies
0.0
0.0
0.0
0.1
Other funding
0.0
0.1
0.4
0.0
-7.6
-7.7
-4.9
-4.6
For the year
-11.4
41.1
-22.8
20.4
Balance brought forward
139.1
127.8
168.9
146.1
Total (balance carried forward)
127.8
168.9
146.1
166.4
Grants distributed
Change in capital
1.0
52
Revenue KI did not reach the funding cap through the settlement for full-time equivalent (FTE) students and annual performance equivalents (APEs) in 2015. KI can nevertheless appropriate the entire funding cap by allocating funds for December performances from 2014 and by settling previous years’ surplus production of approximately SEK 0.6 million. KI’s appropriation document was revised in the middle of 2015 and KI’s funding cap was increased by approximately SEK 9 million. The government appropriation has been adjusted for prices and salaries by 0.79 per cent (2.06 per cent). Further information is available in the appropriation report. Activities within the framework of the medical training and research agreement are reported under the section Collaboration and innovation. Revenues under the item Fees and other remuneration increased in comparison with 2014, which is attributable to an increase in revenues from tuition fees and contract education. Revenues from grants consist mostly of grants from other government agencies transferred to KI for activities in the field of education, in accordance with the appropriations document of each agency.
Expenses This year’s expenses for education are at the same level as in 2014. Education activities account for approximately 16 per cent of KI’s total expenses. Staff costs decreased somewhat compared with last year. The figures for 2014 contain a reallocation of staff costs from research to education, which negatively affected education activities in 2014. The decrease in costs for premises, compared with 2014, is also due to a reallocation of SEK 22 million made in 2014 between research and education, which has affected costs for premises. Financial costs consists of interest on overdue payments and the negative interest on the cash and bank balances. The difference in depreciation between 2014 and 2015 is due to a correction of approximately minus SEK 7 million that was made in 2014. Apart from the correction, depreciation is at the same level as the previous year.
5.4
Education revenue in 2015
Research revenue in 2015
SEK billion
SEK billion
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
FINANCIAL REPORT
Research and education at doctoral level Revenue Research revenue for the year amounted to SEK 5,424.4 million (SEK 5,148.9 million). The direct government funding decreased by SEK 22.8 million or 1.2 per cent compared with 2014, which is in accordance with the appropriations document. The government appropriation has been adjusted for prices and salaries by 0.79 per cent (2.06 per cent). Activities within the framework of the medical training and research agreement are reported under the section Collaboration and innovation. Fees and other remuneration decreased by SEK 7.3 million compared with the previous year, which is primarily explained by a decrease in government-funded contract research. The largest increase is in the item Revenues from grants, which increased by SEK 268 million or 10.3 per cent. A larger share of external resources funded research in 2015 compared with the previous year. The Swedish Research Council is behind an increase in revenues of SEK 112 million compared with 2014. In the category Foundations and organisations, the biggest increase is seen in the Wallenberg Foundations. In the category of companies, AstraZeneca has accounted for a significant increase in 2015. Further information in Table 6. Financial revenues increased by SEK 37.6 million in 2015 compared with 2014. In 2015, the annual average Interest rate on the interest account with the National Debt Office was minus 0.25 per cent (0.47 per cent). Interest income from the Swedish National Debt Office is approximately SEK 1.5 million and is due to negative interest rates on KI’s loans for fixed assets Other financial revenues consist of an appreciation of approximately SEK 31 million on the value of financial fixed assets within asset management and of a capital gain of approximately SEK 32 million from the sale of securities within asset management.
Expenses Total expenses for the year increased by SEK 316 million or 6.3 per cent compared with 2014. Staff costs increased in total by SEK 239.7 million or 9.3 per cent compared with the previous year. There was a salary review during the year with an outcome of 4.67 per cent. The number of employees has also increased during the year, and these factors explain the increase in staff costs. The figures for 2014 contain a reallocation of staff costs from research to education, which affects the comparison between the years. KI’s total costs for premises decreased somewhat compared with 2014. The explanation for this is that KI has during the year begun to apply improvement expenditure on property owned by others, which has had a positive effect on premises costs as some costs are dealt with as depreciations instead of rent surcharges. A correction of SEK 22 million for premises costs was made in 2014 between research and education, which affects the comparison between the years. Apart from the correction, these costs are at the same level as the previous year. Increased other operating expenses, 2.4 per cent, is a result of expansion of activities and the increase is mainly in the cost category Purchase of services.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Research and doctoral education (including asset management) SEK million 2012
2013
2014
2015
Revenue Direct goverment funding Fees and other remunerations Grants Financial income Total revenue
1,732.4 1,762.8 1,919.5 1,896.7 670.1
612.2
601.1
593.8
2,234.6 2,379.1 2,594.5 2,862.5 54.9
50.7
33.8
71.4
4,692.0 4,804.8 5,148.9 5,424.4
Expenses Staff costs Premises costs Other operating expenses Financial costs Depreciation Total expenses
2,363.5 2,507.0 2,568.5 2,808.2 557.7
640.8
640.7
663.1
1,433.2 1,494.2 1,604.5 1,643.6 8.9
9.5
11.7
19.3
177.8
195.6
222.3
230.1
4,541.1 4,847.1 5,047.8 5,364.4
Transfers Government funding
12.2
13.4
12.5
13.2
Funding from other government agencies
34.7
42.2
40.5
68.8
Other funding
84.7
86.9
90.9
136.1
-131.6
-142.5
-143.9
-218.1
For the year
150.9
-42.3
101.1
60.0
Balance brought forward
954.5 1,105.4 1,063.2 1,164.3
Total (balance carried forward)
1,105.4 1,063.2 1,164.3 1,224.3
Grants distributed
Change in capital
Financial costs consist primarily of exchange rate losses of SEK 8.9 million (SEK 7.9 million) and interest expenses of SEK 8.9 million (SEK 2.6 million), on our balance in the Swedish National Debt Office. The annual average interest rate on the deposit account for 2015, is minus 0.25 per cent (0.47 per cent). Exchange rate losses were mainly attributable to currency hedging of SEK 3.6 million (SEK 4.3 million) and SEK 5.3 million (SEK 3.6 million) is due to a stronger exchange rate, in particular for the US dollar and the Euro, linked to supplier invoices. Depreciation increased, mainly due to increased investments.
53
FINANCIAL REPORT
Loans at the National Debt Office Each year new loans are taken in the National Debt Office for the fixed assets that are funded by the government. This takes place twice a year, in June and December, on investments made up to May and November respectively. At the time of the loan, a repayment is simultaneously made that corresponds to the year’s depreciation and retirements. New investments were made in 2015 equivalent to SEK 148.5 million and depreciation amounted to SEK 148.5 million. Total loan debt in the National Debt Office is SEK 612.1 million. The annual average interest rate in 2015 was minus 0.25 per cent (0.47 per cent).
Agency capital Accumulated agency capital, including the change in capital for the year, amounted to SEK 1,434.8 million (SEK 1,358.8 million). Subsidiaries were responsible for SEK 44.1 million (SEK 48.6 million), asset management SEK 98.9 million (SEK 53.9 million) and core activities SEK 1,291.8 million (SEK 1,256.3 million).
Distribution of investment fund portfolio
29,6 %
28,5 %
3,7 % 7,2 %
31 %
Asset management
Interest-bearing securities 28,5 %
Karolinska Institutet manages individual donations intended for medical science at KI. Donations are divided into:
Global equity funds 31 %
Cash 3,7 % Swedish equity funds 7,2 % Alternative investments 29,6 %
1. Funds, which are included in the accounts of KI. 2. Independent foundations, which are their own legal entities with administration linked to KI. For funds that are managed and reported within KI, both yield and capital may be utilised. The independent foundations are individual legal entities and issue their own separate annual reports. Any yield the foundations distribute to KI is included as external grants in KI’s accounts. Summaries of KI’s foundations’ accounts are shown in order to provide a complete picture of KI’s donated assets, regardless of their legal format.
Funds At the end of the year, the market value of the fund portfolio reported in KI asset management amounted to SEK 640.9 million (SEK 247.1 million). This big increase is attributable to the Ming Wai Lau Center (MWLC). The donation for MWLC has been placed in its own portfolio with only interest-bearing securities. At the end of the year, the market value of the MWLC portfolio amounted to SEK 424 million. The following comments on the fund portfolio are excluding MWLC. In 2015, net outflow (the difference between purchased and sold funds) was minus SEK 23.9 million (minus SEK 48.4 million) and the total change in value was SEK 13.1 million (SEK 27.4 million). Holdings in the fund portfolio are distributed as shown above.
54
Yield The total yield of the portfolio excluding MWLC was 5.2 per cent in 2015. The relative yield compared to the market index was 0.4 percentage points. The positive outcome is attributable to Swedish and foreign shares and to alternative investments. In 2015 interestbearing securities have had a negative yield of minus 0.7 per cent. Investments regarding the MWLC portfolio were started in December, which means that it is not possible to state any annual yield.
Yield in per cent compared with the reference index 2012
2013
2014
2015
KI’s funds
6.4
9.8
15.4
5.2
Reference index
6.9
12.6
15
4.8
Yield is stated net, i.e. including dividends and deductions for administrative costs. Share indices are stated inclusive of reinvested dividends.
Indices used for comparison in 2015 Swedish fixed interest
OMRX Bond
30 %
Shares
MS CI World Net Div (SEK)
40 %
Alternative Investments
OMRX T-Bill + 3 %
30 %
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
FINANCIAL REPORT
KI Foundations
Dividend from KI’s funds
76
Associated foundations
SEK million
Dividend from KI’s funds
178
In 2015, SEK 76.3 million was allocated to core activities within KI, according to purpose as shown in the table below.
Dividend from KI’s funds (SEK million) Research grants
2012
2013
2014
2015
35.1
61.4
69.5
75
Travel grants
0.6
0.6
0.6
0.6
Bachelor’s and Master’s education
0.1
0.4
0.1
0.7
Other
20
5.3
0
0
55.8
67.7
70.2
76.3
Total
There are 178 (192) associated foundations that issue annual accounts and reports that are separate to that of the agency. Three (0) new foundations were established in 2015. The asset value of these is SEK 20.4 million. Seventeen foundations have been wound up following decisions, either from the Swedish Legal, Financial and Administrative Services Agency or KI’s Board of Research, that all of the assets may be released with the aim of fulfilling the foundation’s purpose. New donations totalling SEK 4.1 million (SEK 2.9 million) were invested in existing foundations. The value of the foundations’ assets, SEK 1,683 million, increased by SEK 77 million or 4 per cent compared with 2014 after dividends but including new donations. The foundation value at the end of the year consisted of Swedish shares 19 per cent (19 per cent), foreign shares 42 per cent (46 per cent), hedge funds 19 per cent (19 per cent), interest-bearing securities 18 per cent (16 per cent) and cash and cash equivalents 2 per cent (0 per cent). During the year, SEK 28.8 million (SEK 33 million) was distributed to KI from the foundations, SEK 2.9 million (SEK 4.6 million) of which consisted of released restricted assets. The purpose and direction of the grant is determined by the aim of each foundation. For foundations with associated administration, KI received remuneration of SEK 1.4 million (SEK 1.0 million) for administrative costs.
Foundations (SEK million)
External resources to asset management
Asset value
In 2015, KI received a total of SEK 502.6 million (SEK 70.3 million) from external donations. Individual donations of SEK 2.0 million or more are reported below.
Grants awarded
2012
2013
2014
2015
1,235
1,398
1,605
1,683
35.8
29.6
32.7
28.8
Research purpose
Donor
Research within regenerative medicine incl. establishing the Ming Wai Lau Center for Regenerative Medicine
Ming Wai Lau
The Endre A. Balazs Professorship in Innnovation and Entrepreneurship
Dr Endre A. Balazs and Dr Janet L. Denlinger
17.2
Medical research and doctoral education
Gustaf and Tyra Svensson Memorial Fund
15.1
Professorship in clinical treatment
MEDA AB
7.0
Cognitive neurosciences, with a specific focus on brain aging
Stichting af Jochnick Foundation
5.0
Support for young research assistants
Hållsten Research Foundation
4.0
Scientific research primarily concerning cancer
Sune and Charlotta Hays Foundation
3.9
Support for young research assistants
William K. Bowes Jr. Foundation
3.3
Haematological research
Dr Åke Olsson’s Foundation for Haematological Research
2.5
Research concerning gastoenterology and hepatology
Ruth and Richard Julin Foundation
2.3
Support for Igor Adameykos reseach
Hållsten Research Foundation
2.0
Investor's Professorship in Innovative Care
Investor AB
2.0
Support for Sten Eirik Jacobsens research
Tobias Foundation
2.0
Support for the AMORIS database at IMM
Gunnar and Ingmar Jungner Foundation for Laboratory Medicine
2.0
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Amount (SEK million)
422.7
55
FINANCIAL REPORT
Statement of financial performance (SEK in thousands)
Operating revenue Direct government funding Fees and other remuneration Grants Financial income
Outcome
Outcome
01/01/2015
01/01/2014
31/12/2015
31/12/2014
2,803,083
2,790,123
717,751
719,165
2,882,354
2 612,920
71,358
33,817
6,474,547
6,156,024
-3,359,431
-3,128,457
-753,922
-762,632
-2,017,193
-1,944,673
Financial costs
-19,459
-11,819
Depreciation
-244,163
-230,119
-6,394,167
-6,077,700
Operating profit/loss
80,379
78,324
Profit/loss from holdings in associated companies and subsidiary
-4,472
-15,683
2,279
2,306
-2,277
-2,267
2
39
17,675
17,005
Total revenue Operating expenses Staff costs Premises costs Other operating expenses
Total expenses
Collection of general revenue Revenue from fees etc. and other revenue not at the authority’s disposal General revenue transferred to the Government budget Balance Transfers Funding received from the Government budget for the financing of grants Funding received from Government agencies for the financing of grants Other funding received for the financing of grants Grants distributed Balance
CHANGE IN CAPITAL FOR THE YEAR
56
68,869
40,496
136,119 -222,664 0
91,391 -148,892 0
75,909
62,680
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
FINANCIAL REPORT
Balance sheet (SEK in thousands) ASSETS
31/12/2015
31/12/2014
Capitalised expenditure for development
4,346
6,002
Rights and other intangible fixed assets
6,634
4,187
10,980
10,190
31,557
26,061
Machinery, equipment, installations etc.
783,715
824,764
Fixed assets under construction
110,140
81,590
925,412
932,415
44,127
48,599
640,932
199,421
685,060
248,021
Accounts receivable
154,146
145,491
Receivables from other Government agencies
109,701
113,022
1,364
376
265,211
258,890
Prepaid expenses
164,070
167,742
Accrued grant revenue
332,012
244,378
Other accrued revenue
9,973
7,396
506,055
419,516
-399
-405
-399
-405
3,617,853
3,599,344
176,151
109,263
Total cash and bank balances
3,794,004
3,708,607
TOTAL ASSETS
6,186,323
5,577,234
Intangible fixed assets
Total intangible fixed assets Tangible fixed assets Expenditure for improvements to leased property
Total tangible fixed assets Financial fixed assets Holdings in associated companies and subsidiary Other long-term securities holdings Total financial fixed assets Receivables
Other receivables Total receivables Cut-off items
Total cut-off items Settlement with the Government Settlement with the Government Total settlement with the Government Cash and bank balances Balance of the interest-bearing account at the Swedish National Debt Office Cash and bank
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
57
FINANCIAL REPORT
Balance sheet (SEK in thousands) CAPITAL AND LIABILITIES
31/12/2015
31/12/2014
5 238
5 238
43 599
59 282
1 310 010
1 231 647
75 909
62 680
1 434 757
1 358 847
3 562
5 088
Agency capital Government capital Shares of earnings in associated companies and subsidiary Capital brought forward Change in capital according to the statement of financial performance Total agency capital Provisions Provisions for pensions and similar obligations Other provisions
33 214
30 757
36 776
35 845
Loans at the Swedish National Debt Office
612 091
612 138
Liabilities to other Government agencies
139 429
136 363
Accounts payable
262 277
292 660
Other liabilities
205 664
127 695
Total liabilities etc.
1 219 462
1 168 857
139 102
123 564
3 062 310
2 620 924
293 916
269 198
Total cut-off items
3 495 328
3 013 685
TOTAL CAPITAL AND LIABILITIES
6 186 323
5 577 234
84 062 84 062
58 595 58 595
Total provisions Liabilities etc.
Cut-off items Accrued expenses Unexpended grants Other prepaid revenue
Contingent liabilities Other contingent liabilities Total contingent liabilities
58
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
FINANCIAL REPORT
Internal control Karolinska Institutet (KI) conducts systematic internal control at all levels of operations to ensure that the university is performing its duties, achieving established objectives and making sure that its work is being pursued in accordance with operational requirements from the Government. KI is subject to the Internal Audit Ordinance (2006:1228) and is thereby obligated to maintain a quality-assured process for internal control. The Internal Control Ordinance (2007:603) means that KI must prepare a risk assessment, implement control activities, perform systematic follow-up and also document this work. The university’s process for internal control has been designed in accordance with rules and guidelines established by the Board in 2009, with more detailed instructions being adopted on a continuous basis by the Vice-Chancellor. In April 2014, the Board adopted KI’s Strategy 2018, which contains measures within four main areas. During the year, the intentions behind the strategy have been integrated into the processes of operational planning, follow-up and of internal control, which covers the years 2016–2018.
Risk analysis The basis for the risk assessment is KI’s commission in accordance with the Higher Education Act and Ordinance, the appropriation directions and KI’s Strategy 2018. In addition, significant observations in conjunction with internal and external audit were taken into account. A more thorough analysis is to be performed at departments and internal boards every three years. This fell in 2015. On 12 October 2015, the Board established twelve risks concerning the organisation as a whole, based on aggregated documentation. These areas are mainly associated with the university’s core activities in combination with external uncertainties. The three highest rated risk areas have points of contact with Stockholm County Council. Here, KI must find effective forms of collaboration to create opportunities for clinical research and education and to bring about one coherent informatics structure.
Follow-up The Board is ultimately responsible for the follow-up and evaluation of the internal control process in order to ensure the adequacy of risk analysis and associated control activities. This follow-up also forms the basis of the conclusions that can be drawn prior to the assessment of internal control in the annual report. One part of the follow-up of KI’s process for internal control is continuous internal audit. The risks identified constitute an important basis for assessment. Evaluation and review of the university’s operations is also performed by external parties, such as the Swedish Higher Education Authority (UKÄ) and the Swedish National Audit Office. Taken together, this provides the university with continuous proposals and recommendations for further improvements. The quality of operations is an important measure regarding goal achievement and an indirect measure of internal control. In May 2015, the Vice-Chancellor set up a project with the mission of creating an integrated quality management system for the university. A vital objective is to establish conditions for continuous quality evaluation, quality assurance and quality improvement of operations based on Strategy 2018 and external requirements.
Documentation The Board makes an annual decision regarding which documentation is to constitute the basis for the assessment of internal control in connection with signing in the annual report. This documentation has its starting point in implemented work with the mandatory elements for internal control. The Board’s assessment is also based on the Vice-Chancellor’s annual compilation of decision proposals and on reports from the Swedish National Audit Office and KI’s internal audit.
Summary assessment and report of measures In connection with the Board’s overall assessment of internal control at KI, it may be stated that deficiencies might exist. This statement is occasioned by an ongoing matter at KI concerning the researcher Paolo Macchiarini. The Board has appointed an external investigation with regard to this case.
Control activities Based on the Board’s assessment of the risk priorities that must be managed, there are annual decisions on the control activities necessary for fulfilling duties and objectives. In light of the simplified risk analysis performed for 2015, the Board decided on control activities and responsible risk owners for the different areas. Significant results in developed action plans have then been reported to the Board on two occasions during the year. An overall assessment of the effects of these control activities is that the risk level has decreased within some areas, but several risks concerning the organisation as a whole are recurrent and require long-term solutions. In addition, a central part of the control structure is established through the university’s process for operational planning at all organisational levels, but also within the framework of continuous manual or automatic controls within various areas.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
59
APPENDIX
Table 1 Number of first-chocie applicants per admitted student 2012
2013
per % admitted women
Beginner’s programmes Occupational therapy Audiology Biomedicine Biomedical laboratory science
1.3 1.9 0.6 1.0
87 73 62 78
per % admitted women
1.5 2.6 0.6 1.3
2015
2014
88 77 61 79
per % admitted women
1.6 3.1 0.9 1.3
83 80 67 83
per % admitted women
1.7 3.1 1.2 1.4
87 68 60 73
Physiotherapy
3.2
68
3.5
65
4.0
63
4.2
63
Speech and language pathology
3.8
94
4.5
91
2.5
90
3.1
87
Medicine
6.8
57
6.8
58
7.8
58
8.0
59
Optometry
1.8
83
2.0
76
1.8
83
1.8
85
Psychology
3.9
73
6.0
72
6.1
68
5.6
75
Radiography
1.4
77
2.3
72
2.2
80
1.9
73
Nursing
3.0
88
3.2
88
3.1
86
3.2
84
Dental hygiene
4.7
92
5.4
93
4.1
90
5.0
93
Dentistry
4.2
70
4.6
69
4.4
70
4.5
68
Midwifery
5.3
100
5.0
100
3.6
100
2.8
100
Psychotherapy
2.0
81
1.4
83
1.6
81
1.3
88
Continuation programmes
Specialist nursing
2.2
86
2.0
87
1.7
86
2.0
86
Odontological prophylactics
1.3
100
1.0
93
1.2
95
1.1
100
1.4
95
-
1.5
87
3.8
68
5.0
3.5
78
MSc (1 year) – Work and health MSc (1 year) – Diagnostic cytology
1.7
80
MSc (1 year) – Global health
2.6
79
78
MSc (1/2 year) – Clin. medical science
2.4
88
2.3
81
1.7
82
1.2
84
MSc (1 year) – Clinical optometry
1.3
89
1.4
91
1.5
86
1.3
86
1.0
59
-
1.1
64
MSc (1/2 year) – Medical education
60
-
-
MSc (2 year) – Bioentrepreneurship
0.9
57
1.1
63
1.2
49
1.3
58
MSc (2 year) – Biomedicine
2.4
63
2.7
60
2.3
62
2.0
67
MSc (2 year) – Public health sciences
1.4
68
1.4
73
1.9
63
1.4
65
61
MSc (2 year) – Health informatics
0.8
48
1.2
MSc (2 year) – Toxicology
0.9
55
-
Total
2.9
75
3.1
75
1.5
40
1.4
57
1.1
64
1.0
62
3.2
72
3.0
73
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
APPENDIX
Table 2 First-year students registered for term 1 2012
Beginner’s programmes Occupational therapy Audiology Biomedicine Biomedical laboratory science Physiotherapy Speech and language pathology Medicine
2013
2015
2014
total
% women
total
% women
% total women
total
% women
94 24 75 95
86 71 64 78
92 25 77 101
89 68 68 81
95 18 79 82
86 89 70 83
97 21 73 77
87 67 71 71
151
74
149
63
32
84
33
82
151
58
145
62
47
87
37
89
325
48
320
49
334
49
329
55
Optometry
62
85
59
75
58
83
56
86
Psychology
84
65
85
59
78
71
90
64
Radiography
50
74
57
70
46
80
56
70
367
86
354
86
343
86
345
83
Dental hygiene
Nursing
49
96
45
98
49
88
47
91
Dentistry
97
70
96
65
94
63
95
63
Midwifery
63
100
67
100
66
100
80
100
Psychotherapy
16
75
16
88
15
80
19
95
633
89
647
89
576
87
574
89
23
100
23
87
14
100
26
100
90
96
-
81
90
71
31
Continuation programmes
Specialist nursing Odontological prophylactics MSc (1 year) – Work and health
-
MSc (1 year) – Diagnostic cytology
15
80
-
MSc (1 year) – Global health
32
75
31
MSc (1 year) – Public health in disasters
-
65
-
-
35
77
15
53
7
86
12
58
MSc (1/2 year) – Clin. medical science
80
85
83
82
85
80
78
86
MSc (1 year) – Clinical optometry
26
88
20
90
27
85
25
92
MSc (1/2 year) – Medical education
-
37
62
-
37
62
MSc (2 year) – Bioentrepreneurship
33
61
25
60
32
59
38
66
MSc (2 year) – Biomedicine
38
61
39
72
38
61
37
78
MSc (2 year) – Public health sciences
49
82
43
81
63
57
59
80
MSc (2 year) – Health informatics
36
36
34
50
34
38
28
68
-
-
6
50
21
52
-
30
57
27
67
2,570
77
2,663
2,492
75
2,630
77
MSc (2 year) – Molecular tech. in life sc. MSc (2 year) – Toxicology Total
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
-
77
61
APPENDIX
Table 3 Full-time equivalent students (FTEs) 2012
2013
2015
2014
total
% women
total
% women
Beginner’s programmes Occupational therapy Audiology Biomedicine Biomedical laboratory science Public health sciences
205 48 145 196 65
88 74 62 82 88
213 48 158 205 38
89 70 65 82 92
Physiotherapy
340
70
357
67
370
67
365
64
94
93
111
90
108
90
116
88
1,516
54
1,591
54
1,667
53
1,651
53
103
89
110
85
127
82
130
81
1
50
0
-
0
-
0
-
Speech and language pathology Medicine Optometry Medical informatics Podiatry
% total women
224 55 157 205 14
88 70 69 84 90
total
% women
231 58 172 204 0
88 72 71 82 -
0
-
0
-
0
-
-
-
Psychology
251
70
285
68
300
68
320
69
Radiography
105
77
114
78
112
80
110
76
Nursing
601
85
788
85
792
87
806
88
86
94
82
94
85
95
89
92
396
66
412
65
433
65
443
66
35
75
19
79
5
89
-
-
95
98
101
100
101
100
111
100
Dental hygiene Dentistry Dental technology Continuation programmes Midwifery Psychotherapy Specialist nursing Odontological prophylactics
81
21
82
20
82
17
82
88
458
91
456
89
447
89
20
100
20
94
15
88
16
100
MSc (1 year) – Work and health
29
95
34
95
31
97
36
95
MSc (1 year) – Diagnostic cytology
14
75
7
80
0
-
-
-
MSc (1 year) – Global health
26
81
25
77
24
75
22
77
-
-
-
-
2
81
3
100
69
83
71
83
74
82
71
83
MSc (1 year) – Public health in disasters MSc (1/2 year) – Clin. medical science MSc (1 year) – Clinical optometry
23
94
23
89
22
87
27
88
MSc (1/2 year) – Medical education
14
82
16
76
15
74
15
73
MSc (2 year) – Bioentrepreneurship
24
58
35
64
41
63
46
61
MSc (2 year) – Biomedicine
71
61
68
61
69
65
70
66
MSc (2 year) – Public health sciences
79
81
68
84
65
85
75
78
MSc (2 year) – Health informatics
33
46
29
39
27
49
22
56
-
-
-
-
-
2
60
23
52
19
49
19
53
26
66
701
81
488
80
341
78
362
78
5,885
73
6,014
73
5,978
72
6,062
72
MSc (2 year) – Molecular tech. in life sc. MSc (2 year) – Toxicology Single subject courses Total
62
22 457
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
APPENDIX
Table 4 Full-time equivalent students (FTEs) and annual performance equivalents (APEs) 2012
2013
FTE
APE
%*
FTE
APE
Beginner’s programmes Occupational therapy Audiology Biomedicine Biomedical laboratory science Public health sciences
205 48 145 196 65
193 46 128 166 69
94 96 89 84 105
213 48 158 205 38
Physiotherapy
340
315
93
94
90
96
1,516 1,402
93
Speech and language pathology Medicine Optometry
2015
2014 FTE
APE
%*
FTE
204 96 45 93 136 86 185 90 45 119
224 55 157 205 14
217 97 55 100 141 90 186 90 17 122
231 58 172 204 0
216 54 142 184 2
94 94 82 90 -
357
360 101
370
355
96
365
338
93
111
105
95
108
101
93
116
109
94
1,591 1,500
94
1,667 1,660 100 1,651 1,583
96
%*
APE
%*
103
102
98
110
101
92
127
114
89
130
121
93
1
2
-
0
2
-
0
1
-
0
2
-
Podiatry Psychology Radiography
0 251 105
1 223 100
89 95
0 285 114
0 270 106
95 93
0 300 112
0 276 92 114 102
320 109
290 91
91 83
Nursing
601
521
87
788
713
90
792
745
94
806
733
91
Medical informatics
Dental hygiene Dentistry Dental technology
86
78
91
82
72
88
85
70
82
89
75
84
396
364
92
412
363
88
433
396
91
443
416
94
35
41
117
19
20 109
5
7 139
-
-
-
95
84
89
101
111
102
92
Continuation programmes Midwifery Psychotherapy
96
96
101
94
93
22
18
83
21
20
95
20
18
88
17
16
93
457
428
94
458
409
89
456
423
93
447
409
91
Odontological prophylactics
20
14
69
20
25 125
15
13
88
16
9
54
MSc (1 year) – Work and health
29
31
108
34
22
64
31
36 117
MSc (1 year) – Diagnostic cytology
14
14
103
7
8 109
0
0
MSc (1 year) – Global health
27 106
Specialist nursing
26
22
85
25
MSc (1 year) – Public health in disasters
-
-
-
-
MSc (1/2 year) – Clin. medical science
69
67
97
MSc (1 year) – Clinical optometry
23
24
MSc (1/2 year) – Medical education
14
11
MSc (2 year) – Bioentrepreneurship
24
MSc (2 year) – Biomedicine
71
MSc (2 year) – Public health sciences MSc (2 year) – Health informatics
28
79
-
-
-
19
87
24
22
-
22
-
2
2
94
3
71
72 102
74
69
93
71
65
101
23
24 104
22
21
96
27
28 104
83
16
12
15
14
97
15
14
18
76
35
30
86
41
41 100
46
39
84
70
98
68
66
97
69
65
95
70
67
96
79
82
104
68
69 102
65
60
92
75
70
94
33
28
85
29
28
96
27
29 106
-
-
-
-
-
-
-
23
19
83
19
23 120
19
701
535
76
488
5,885 5,307
90
MSc (2 year) – Molecular tech. in life sc. MSc (2 year) – Toxicology Single subject courses Total
36
-
-
429
6,014 5,589
75
88
341
3 104 91 94
22
22
98
-
2
1
43
20 107
26
20
79
362
268
74
6,062 5,534
91
233
68
93 5,978 5,613
94
*Performance indicator
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
63
APPENDIX
Table 5 Degrees 2012
Professional qualifications Occupational therapy Audiology Midwifery Biomedical lab science Physiotherapy Speech and language pathology Medicine Optometry Psychology Psychotherapy Radiography Nursing Specialist nursing Dental hygiene Dentistry Dental technology Total professional qualifications General qualifications University diplomas BSc
2015
2014
total
% women
total
% women
60 18 56 52 107 4 272 29 18 14 39 14 419 38 70 13 1,223
88 83 96 85 64 100 54 97 72 79 74 86 89 97 77 69 78
52 10 56 57 108 30 219 31 32 21 23 113 378 39 70 17 1,256
96 80 98 84 69 90 59 90 75 81 74 90 90 92 63 59 80
66 15 65 53 108 30 240 26 36 12 38 226 397 33 76 11 1,432
83 67 100 89 68 100 56 88 67 83 84 81 91 94 70 91 80
71 17 64 65 101 21 292 38 47 13 33 237 439 46 94 1,578
89 71 100 85 77 95 56 87 72 77 88 89 90 100 61
1 351
100 83
0 464
86
1 488
100 82
3 422
67 85
15 3 27 43 4 20 7 177
100 100 70 81 50 90 71 89
19 1 30 70 2 21 4 283
95 0 70 84 100 90 50 90
43 3 30 68 13 23 5 484
95 67 70 81 77 83 100 88
67 57 78 36 86 100 100 100 82 33 100
19 34 43 19 11 3 4 21 11 21 1
58 50 86 42 91 100 100 52 91 57 100
18 33 41 18 11 3 5 7 10 2 4
78 73 76 56 82 100 100 100 60 0 100
1,106
82
1,246
85
2,538
81
2,824
82,2
MSc (1 year) Work and health Biomedical lab science Global health Clinical medical science Medical teaching and training Optometry Radiography Other main subjects
0 1 26 39 0 20 4 69
Master’s qualifications Bioentrepreneurship Biomedicine Public health Health informatics Clinical medical science Speech and language pathology Medical teaching and training Dentistry Psychology Toxicology Broad MSc (1 year)
14 38 35 9 9 0 0 8 7 17 7
38 57 53 71
3 30 51 14 7 1 3 4 11 3 4
655
79
891
84
Total qualifications awarded
1,878
78
2,147
82
Total graduates
1,668
Total general qualifications
64
2013
100 77 90 95 75 77 57 66 77 56 89
1,758
% total women
1,964
total
% women
80
2,105
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
APPENDIX
Table 6 Revenue 2015, largest sources of funding, SEK million Research councils Swedish Research Council Forte Formas Government agencies Royal Institute of Technology Vinnova The National Board of Health and Welfare Kammarkollegiet Stockholm University The Swedish Armed Forces The Swedish Social Insurance Agency The Public Health Agency of Sweden The Swedish Institute SIDA Organisations and foundations The Wallenberg Foundations The Swedish Cancer Society The Swedish Foundation for Strategic Research The Swedish Heart-Lung Foundation The Swedish Childhood Cancer Foundation The Erling-Persson Family Foundation The Torsten and Ragnar Söderberg Foundations KI-foundations The Swedish Brain Foundation Gustaf and Tyra Svensson Memorial Fund
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
819,9 117,9 31,7
County and municipal councils Stockholm County Council Västra Götaland County Council Botkyrka municipality
418,4 5,1 3,4
137,2 45,2 32,6 25,9
Companies AstraZeneca AFA Insurance Novo Nordisk KI Science Park
137,6 32,0 12,4 11,9
17,9 11,7 9,7 9,5 9,5 7,7
194,5 164,2 97,0 71,6 70,2 57,1 52,4 38,3 20,2 16,3
Meda Pfizer Merck & Co (MSD) Biogen Idec Johnson & Johnson CBD Solutions Foreign organisations and foundations European Union (EU) CHDI Foundation National Institutes of Health (NIH) The Novo Nordisk Foundation OECD Stichting af Jochnick Foundation University of North Carolina Kingdom of Saudi Arabia Aarhus University Hospital Scripps Research Institute
10,0 7,5 6,6 5,6 5,5 5,4
233,5 19,6 15,4 13,8 11,9 9,9 7,7 7,3 5,6 5,3
65
THE UNIVERSITY BOARD
Resolution on the annual report and assessment of internal control The University Board hereby resolve to submit the annual report for 2015. We confirm that the annual report provides a true and fair impression of the authority’s results, costs, revenue and of the agency’s financial position. We judge that deficiencies might exist in the authority’s internal control with respect to the following1:
An ongoing matter at Karolinska Institutet (KI) indicates that deficiencies might exist in KI’s internal control. The Board has appointed an external investigation with regard to this case.
Stockholm, 19 February 2016
Lars Leijonborg, Chair
Karin Dahlman-Wright, Acting Vice-Chancellor
Annika Andersson, Deputy Chair
Dan Andersson
Elias Arnér Petter Berg Anders Blanck Susana Borrás Eskil Franck Arash Hellysaz Anna Karlsson Lena von Koch Matilda Liljedahl Torbjörn Rosdahl Charlotte Strömberg
1 See
66
also the chapter on Intern control regarding measures taken or planned with reference to the deficiencies reported.
KAROLINSKA INSTITUTET ANNUAL REPORT 2015
Karolinska Institutet ANNUAL REPORT 2015 Design: Sofia Lindberg | Print: E-print 2016
|
ISBN: 978-91-85681-83-9
A
Karolinska Institutet’s Annual Report 2015 Compiled by: The Central Administration, Karolinska Institutet Published by: The Communication and Public Relations Office, Karolinska Institutet SE-171 77 Stockholm ki.se
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