PARKINSON'S DISEASE FOUNDATION
Annual Report 2011
THE
PDF EFFECT
The mission of the Parkinson's Disease FoundationÂŽ (PDFÂŽ ) is two-fold: to understand and find the cure to Parkinson's disease and related movement disorders; and, for as long as this search continues, to ensure that those individuals and families who live with Parkinson's are able to achieve and maintain the best possible quality of life.
Cover and inside cover Members of the Parkinson's Support Group of the Mid-Hudson Valley gather at their third annual Parkinson’s Awareness Month walk in Poughkeepsie, NY, which benefited PDF.
Table of Contents 2
Letter from Leadership
4
Energizing Science
8
Empowering People
14
Improving Care
16
Our Donors
32
Our Researchers
34
Financial Reports
36
Our People
The theme of our Annual Report this year is “The PDF Effect.” What does this line mean? To us at the Parkinson’s Disease Foundation (PDF), it means focusing not just on what we put into our work, but what comes out of it. Not just the shape and direction of the programs we design — and with your help, execute — but the impact of those programs on the pace of science, and on the lives and futures of the people we serve. Take, for example, the research programs we fund (see the section Energizing Science). We have highlighted just four research grant recipients (selected from among the dozens we funded in 2011) to illustrate what we do in this area: a young student Fellow from Germany; a senior scientist at Memorial Sloan-Kettering Cancer Center (MSKCC); a team of scientists at the University of British Columbia; and a clinical researcher at the PDF Research Center at Rush University. They were selected through our rigorous peer-review process because of their superior track records in the past and high potential for creative contributions in the future. But what exactly are they accomplishing with the money we give them? Well, the student Fellow is working on finding
2 | Letter from Leadership
new “targets” for Parkinson’s treatments in a lab at Massachusetts General Hospital. The MSKCC scientist is studying the role of stem cells in potential Parkinson’s treatments. The Canadian team is studying a specific gene mutation that — though rare — may help illuminate a whole area of neurodegenerative disease. And the Rush University scientist has found a possible “marker” for Parkinson’s in the colon of people with the disease. These people and others like them, make up an A-team of scientific explorers, working at the edge of the known universe of neuroscience. And they are getting things done — things that will answer questions, solve problems and improve lives. Then there are the ways we work with people who live with Parkinson’s and their loved ones (see the section Empowering People). Here, “The PDF Effect” is of two main kinds. One is to provide the information that people can use to improve their own lives as “managers” of their Parkinson’s — for example, our national HelpLine, our portfolio of publications and our popular PD ExpertBriefings online seminar series. The other is to provide programs that can em-
Letter from Leadership
power people with leadership potential to serve as advocates for the development of new research and treatments. Through our Parkinson’s Advocates in Research program, lay advocates are trained through three-day institutes and more recently, through online courses, to play leading roles in advancing research. The work that these people do helps themselves, and it helps their communities. It is all part of “The PDF Effect.” A third area that carries the stamp of “The PDF Effect” is the quality of care that is provided to people with Parkinson’s (see the section Improving Care). Take for example our innovative online Parkinson’s course for physical therapists — designed by a blue-ribbon committee of leaders in that profession, and modeled on a course in Parkinson’s for nurses that we developed a year earlier. Or take the network of training initiatives we provide for future leaders of the movement disorders profession, in PDF-funded medical centers like Columbia and Rush Universities, and through professional organizations like the Parkinson Study Group and the American Academy of Neurology. Of course “The PDF Effect” would not exist without Our Donors — 41,000 of them in 2011 alone. In this report, we list the names of more than 1,600 donors who made gifts of $500 or more between July 1, 2010 and December 31, 2011 to support the research and other activities of the Parkinson’s Disease Foundation. We thank them for all they have done to make our work possible, and
we recognize the proceeds of their generosity in the section Financial Reports. From these and all our other sources of revenue, PDF received a total of $10,284,389 during the fiscal year that ended June 30, 2011 — an increase of $757,979, or more than seven percent, over the amount we received during the same period in 2010. Nor would “The PDF Effect” exist without the people who make it all happen, from day to day. These include a devoted Board of Directors and People with Parkinson’s Advisory Council; an outstanding network of scientists and educators who volunteer their services to PDF; and a creative and industrious professional staff of 24. They are the people who make “The PDF Effect” possible. We thank them, one and all. Sincerely yours,
Robin Anthony Elliott Executive Director
Lewis P. Rowland, M.D. President, Board of Directors
The PDF Effect: Annual Report 2011 | 3
Since its founding in 1957, the Parkinson’s Disease Foundation has supported hundreds of research projects throughout the world — furthering Parkinson’s science and improving the lives of individuals touched by the disease. PDF's funding philosophy is to empower stakeholders — Parkinson’s scientists, clinicians and other members of the scientific community — to identify novel questions about, and answers to, the puzzle of Parkinson’s. The research program is guided by PDF’s Scientific Advisory Board, joined by representatives of PDF's Parkinson’s Advocates in Research program.
Identifying New Targets for Parkinson’s Treatments
α-synuclein levels
an advanced imaging technique that provides a Excessive amounts of the protein alpha-synu“window” on a living mouse’s brain, Mr. Ebrahimiclein in neurons can predispose a person to Fakhari and coworkers showed that both pathways Parkinson’s disease (PD). Now a study in the Octorecycle alpha-synuclein. UPS is the main recycling ber 12, 2011 issue of The Journal of Neuroscience pathway for alpha-synuclein under norhas identified two distinct cellular pathmal conditions, whereas ALP kicks in ways that help neurons dispose of un300% only when levels of alpha-synuclein are wanted alpha-synuclein. high, as in the neurons of some people Previous studies on the roles of the with Parkinson’s. Enhancing the work of two recycling mechanisms, the ubiqui200% UPS or making the ALS mechanism kick tin-proteasome system (UPS) and the in sooner (before too much alpha-synuautophagy-lysosome pathway (ALP), in 100% clein accumulates) should be studied to alpha-synuclein degradation have produced conflicting results. To settle this slow down or even prevent Parkinson’s. debate, Darius Ebrahimi-Fakhari, a medThese findings may help scientists 0 No Inhibitor Inhibitor ical student at the University of Heidelunderstand what causes Parkinson’s berg in Germany, undertook a PDF(e.g., how the recycling mechanisms are This graph illustrates the accumulation of alphafunded summer student fellowship in faulty) and help scientists identify new synuclein in the presence of inhibitors of the cell's targets for Parkinson’s treatments. the lab of Pamela McLean, Ph.D., at two recycling pathways. Massachusetts General Hospital. Using
4 | Energizing Science
Energizing Science
Clarifying the Role of Stem Cells in Parkinson's Treatments Scientists, funded in part by PDF, announced in the November 2011 issue of Nature, that they have transformed pluripotent stem cells into dopamine neurons and implanted them into the brains of animals. Pluripotent stem cells, such as those derived from embryos and more recently induced from adult skin cells, have the potential to develop into nearly any cell type, but scientists have had trouble transforming these stem cells into the desired cell type. For the first time, Lorenz Studer, M.D., at the Memorial Sloan-Kettering Cancer Center and his colleagues appear to have identified the correct conditions necessary to transform pluripotent stem cells exclusively into dopamine neurons that resemble those lost from the same brain region affected by Parkinson’s, that grow and perform well in animals, and do not produce tumors. The fact that these transplanted neurons reduced some Parkinson’s symptoms in animals is a good sign for potential therapeutic applications in people living with PD.
Before stem cell therapy for Parkinson’s becomes a reality, however, significant challenges remain. Longer-term experiments in monkeys must be done to show that the neurons can survive and avoid tumor formation for longer than one month and can alleviate PD symptoms. Animals in these experiments were also given immune-suppressing drugs to prevent their bodies from rejecting the transplanted cells. These drugs have substantial side effects when taken long-term, which must be balanced against the benefit of improved PD symptoms. Furthermore, stem cells may replace the cells that are affected by Parkinson’s, but they will probably not stop the neurodegenerative process. Nevertheless, until a safe and effective stem cell replacement therapy has been demonstrated, this new protocol can been used in the laboratory to efficiently generate large quantities of the dopamine neurons necessary to screen and test potential drug therapies currently under investigation.
Newly made dopamine-producing neurons derived from stem cells
“The fact that these transplanted neurons reduced some Parkinson’s symptoms in animals is a good sign for potential therapeutic applications in people living with PD. ” The PDF Effect: Annual Report 2011 | 5
Energizing Science
Discovering a New Genetic Mutation Linked to Parkinson's developed Parkinson’s and others did not. In the past, this type of DNA analysis has been very difficult, requiring examination and DNA collection from large numbers of affected families. The University of British Columbia researchers instead used a new and efficient technique called whole exome sequencing, which focuses on small, but important, sentence-like sections of DNA. These sections govern the production of proteins. Since mutated proteins are most often the cause of genetic diseases, they reasoned that mutations linked to inherited PD would be found here. Like most other genetic causes of PD, this newly identified genetic mutation is exceedingly rare, resulting in very few cases of PD. Nevertheless, a better understanding of how a VPS35 mutation causes cellular processes to go awry may help scientists to unravel the causes of PD and other neurodegenerative diseases.
Using a new, cutting-edge technology for gene sequencing, researchers funded in part by PDF have discovered a new gene called vesicular sorting protein complex 35 (VPS35) that is linked to Parkinson’s in people with familial PD. The results appeared in the July 15, 2011 issue of the American Journal of Human Genetics. In recent years, researchers have identified about a dozen genes that either cause Parkinson's or increase the risk of developing the disease. To search for a new PD gene, an international team of researchers led by Carles Vilariño-Güell, Ph.D., and Matthew J. Farrer, Ph.D., of the University of British Columbia, Vancouver, Canada, focused on a family from Switzerland in which 11 people in three generations were diagnosed with PD. They compared the DNA of family members with PD to that of unaffected family members to search for differences that could explain why some members
2
1
I
II
1
2
M 64
wt
2
III IV
1
3
M 46
3
M
3
4
5
6
M 48 4
5
6
wt 2
M 47
7
7
8 2
9
10
M 60 8
9
2
M 45
10
wt
M 42 11
M 49
12
13
2
M 54
14
wt
A pedigree of the original Swiss family used to identify the VPS35 mutation. Filled symbols indicate individuals affected with PD and the number below the symbol indicates their corresponding age at disease onset. Individuals are either mutation carriers (M) or have a normal (wt) genome. Square symbols are male and round symbols are females. Diamond symbols are number of children, no sex specified. Slash marks indicate deceased individuals.
6 | The PDF Effect: Annual Report 2011
Finding a Biomarker for Parkinson's Disease Unlike other conditions that can be diagnosed through blood tests or biopsies, there is no definitive test or "biomarker" that can identify Parkinson's or trace its development. A study funded in part by PDF and published in the July 2011 issue of Movement Disorders suggests that the presence of the alpha-synuclein protein in the colon may be a biomarker for the disease.
leagues published additional results in the June 2012 issue of Movement Disorders suggesting that doctors may be able to diagnose early Parkinson's with a colonoscopy. In this study, Dr. Shannon detected alpha-synuclein in colon tissue samples removed two to five years before the individuals reported any symptoms of Parkinson’s (see image below). If the findings from this very small study are replicated in a
“Early detection of Parkinson's, before the significant loss of dopamine-producing neurons, would help facilitate a search for a cure, or for interventions that slow disease progression.
”
In people with PD, the alpha-synuclein protein forms abnormal clumps in cells, and these toxic aggregates kill dopamine-producing neurons. One hypothesis suggests that Parkinson's may actually begin in neurons of the intestinal wall and spread by cell-to-cell transfer of alpha-synuclein through the vagus nerve to the brain. In support of this hypothesis, Kathleen Shannon, M.D., and her colleagues at the PDF Research Center at Rush University Medical Center detected alphasynuclein in colon tissue samples of people with early Parkinson's. This study is the first to demonstrate alpha-synuclein aggregation in colon tissue. Building upon this work, Dr. Shannon and col-
larger number of samples, it may be possible to use colonoscopy to predict who may develop PD. Doctors already recommend that people age 50 and older have a colonoscopy every three to ten years for colon cancer surveillance. For those who would be interested, the same biopsy may be able to predict their risk for Parkinson’s. Therefore, it would be relatively easy to test colon tissue biopsies for both cancer and the alpha-synuclein protein. Although these initial results are promising, it will be important to confirm the results in larger populations of people with and without PD, as well as in people with Parkinson's-like disorders.
Energizing Science | 7
Central to PDF’s philosophy is the belief that people with Parkinson’s must be key partners on initiatives that move the cause forward. To make this happen, PDF recognizes that the community needs certain tools to effectively make a difference. In recent years, PDF has made a commitment to providing these tools to empower people touched by Parkinson’s to become actively engaged in research, education and advocacy efforts in their communities.
Finding Ways to Speed New Treatments The current process that brings new Parkinson’s treatments to market is very slow. There are many factors that may contribute to this delay but PDF believes that in order to speed this process, people with Parkinson’s must be primary partners in research alongside scientists, government and industry. PDF's Parkinson’s Advocates in Research (PAIR) program offers intensive in-person trainings, known as Learning Institutes, and an online course to provide people touched by Parkinson’s with the scientific knowledge and leadership skills needed to advance research in their communities. Since its launch in 2008, the PAIR network has expanded to include more than 180 Research Advocates from 38 states. In 2011, PDF Research Advocates were involved in a wide range of leadership activities including the examples below. Guiding Parkinson’s Research A PDF Research Advocate since 2009, Diane Cook was named in 2011 to the Board of Directors of the Colorado Neurological Institute (CNI) where she assists with the review of clinical trials. Ms. Cook is also co-investigator with Rajeev Kumar, M.D., of CNI, and Katen McRae, M.D., of the University of Denver, on a research study to determine the efficacy of a model training program she helped to create that is specifically geared toward people with Parkinson’s disease in a support group environment. The model involves incorporating skills of self-efficacy into the support group’s curriculum. Ms. Cook’s efforts have helped nearly 100 people with Parkinson’s get involved with research.
8 | Empowering People
Empowering People
Educating Their Community About Research Studies A PDF Research Advocate since 2010, Bernie Snead believes that one of the simplest ways to advance research is to let the community know what they can do to help. In collaboration with Parkinson Association of the Carolinas (PAC), Mr. Snead brought the latest information to support groups in North and South Carolina in 2011. Interweaving the PDF guide, Getting Involved in Parkinson’s Research, with his own personal experiences in volunteering for trials, Mr. Snead presented to 13 support groups in six months and was selected to be a member of the PAC Speakers Bureau. Following Mr. Snead’s presentations, the number of support group members who stated that they were likely to participate in a clinical trial increased by 50 percent. Filling Gaps in Parkinson’s Research Another PDF Research Advocate from 2010, Ronnie Wanetick collaborates with major Parkinson’s research centers in Northern California to address a major barrier to Parkinson’s research: improving the system that informs people of clinical trials taking place within their community. Working with study coordinators at the University of California at San Francisco, The Parkinson’s Institute and the University of California at Davis, Ms. Wanetick receives a list of all enrolling studies and she then distributes this list to support groups in her area. In just over two months, 13 individuals have enrolled in studies because of this system, dramatically reducing the length of time that it has taken clinical trials at these centers to enroll.
2011 Learning Institute Graduates
“It will be invaluable to have knowledgeable PDF Research Advocates join our team of researchers, doctors and other professionals, in order to prioritize Parkinson’s disease research and improve studies. ” Jay Nutt, M.D.
Oregon Health & Science University (OHSU) Parkinson Center of Oregon and Movement Disorders Program
The PDF Effect: Annual Report 2011 | 9
Empowering People
Connecting the Parkinson’s Community to Resources A top priority for PDF remains the dissemination of accurate, accessible information about Parkinson’s to people with the disease and their families. The cornerstone of our efforts is our national toll-free HelpLine, which is staffed by trained information specialists who can answer questions about Parkinson’s and connect people living with the disease to community resources. In 2011, more than 5,000 people from all over the country were advised through our HelpLine. To address the financial concerns facing many people with Parkinson's, PDF once again awarded $50,000 in 2011 to the Melvin Weinstein Parkinson’s Foundation to help individuals who meet certain eligibility requirements pay for a home health aide or visiting nurse and purchase such medical equipment as wheelchairs, walkers and canes. Since 2008, the Helen M. Lynch Direct Aid Fund of the Parkinson’s Disease Foundation and the Melvin Weinstein Parkinson’s Foundation has helped over 500 people in the Parkinson’s community.
“Thank you for the very useful information you provide. Your publications are a staple in the educational materials that we provide to our newly diagnosed Parkinson’s patients.
”
Lisa H., R.N. Fayetteville, AR
10 | The PDF Effect: Annual Report 2011
PDF also offers a growing portfolio of educational materials that are developed in response to community needs. In 2011, over 800,000 print educational publications were distributed worldwide. The Second Edition of our most popular and visible publication, the Parkinson’s Disease Resource List, was released in April 2011. The print and online version of this new edition includes over 750 resources for the Parkinson’s community throughout the US and around the world. The concept for this publication developed from conversations with our People with Parkinson’s Advisory Council. In response to requests from the community, PDF added 10 fact sheets in 2011 to our line of educational materials. These fact sheets cover a range of topics from Fatigue and Sleep Disorders to Caring for the Care Partner. PDF now has over 50 fact sheets that offer in-depth information about specific areas of Parkinson’s treatment and care. They are written by physicians and people living with Parkinson’s and many are available in Spanish.
Providing Access to Leaders in Parkinson’s Research and Care
“I have learned so much from your seminars. They have been clear and understandable for someone without a science background. They have made it much easier to face the diagnosis and put it in perspective.
”
LISTEN WATCH LEARN
Ann M.
Chicago, IL
Recognizing the ongoing need to provide people with Parkinson's and their families with research updates and strategies for living well with the disease, PDF continued in 2011 our popular PD ExpertBriefings online seminars. This program provided people with Parkinson's around the country, and the world, with first-hand access to the insights of some of those who are at the forefront of Parkinson's research and care. Topics covered in 2011 included: • Physical Therapy and PD — What You Need to Know, led by Heather Cianci, P.T., M.S., G.C.S., of the Dan Aaron Parkinson’s Rehabilitation Center (Good Shepherd/Penn Partners) at Pennsylvania Hospital in Philadelphia, PA • Cognition and PD: What You’ve Always Wanted to Know But Were Too Afraid to Ask, led by Alexander I. Tröster, Ph.D., of the University of North Carolina at Chapel Hill
• Understanding Pain in Parkinson's, led by Jeffrey Wertheimer, Ph.D., of Cedars-Sinai Medical Center in Los Angeles, CA • Impulsive and Compulsive Behaviors in Parkinson’s, led by Daniel Weintraub, M.D., of the University of Pennsylvania in Philadelphia, PA • Caring for a Person with Late Stage Parkinson’s, led by Joan Gardner, R.N., B.S.N. and Rose Wichmann, P.T., of the Struthers Parkinson's Center in Minneapolis, MN These seminars are available for viewing from the comfort of home, 24 hours a day, seven days a week. For those who may not have the technology to watch online, PDF offers DVDs of this series. Since 2007, PDF has held more than 30 online seminars and in 2011, more than 10,000 individuals in 38 countries participated in at least one of our PD ExpertBriefings.
• What's in the PD Pipeline?, led by Michael Schlossmacher, M.D., of the University of Ottawa
Empowering People | 11
Empowering People
Making an Impact During Parkinson’s Awareness Month In 2011, PDF once again took the lead in helping the Parkinson’s community mark April as Parkinson’s Awareness Month. The theme of our 2011 campaign was “Shatter the Myths” about what it means to live with Parkinson’s by spreading the word, educating the community and supporting research for the cure. The theme resonated with many individuals across the country as captured in the inspiring highlights below. Spreading the Word • 20 individuals, including Ruth Pearce in Gainesville, GA, displayed the Parkinson’s Quilt in 11 states. An estimated 2,500 people visited the quilt during April. • Many individuals, including PDF Research Advocates Jim Patterson of Dunedin, FL, and Patti Meese of Scottsdale, AZ, successfully had proclamations signed by local, state, and federal officials. The United States Senate also proclaimed April as Parkinson’s Awareness Month. Sample Chock full o’Nuts cup
• Chock full o’Nuts helped PDF’s efforts by featuring an awareness message on one million coffee cans, and an advertisement in a national Sunday circular and on cups and displays in stores in New York City.
Members of PDF’s People with Parkinson’s Advisory Council at the 2011 Parkinson’s Unity Walk
“It is amazing to experience what people can do to show support for those of us who are living with Parkinson’s disease. ” Jerry T.
Mount Vernon, NY
12 | The PDF Effect: Annual Report 2011
Educating the Community • More than 1,400 individuals wore one of the Parkinson’s Awareness Month t-shirts designed by winners of the annual design contest, Marian Bumala, of La Honda, CA, and Stephanie Longo, of Cherry Hill, NJ. • PDF Research Advocates John Baumann of Louisville, KY, and Linda Hinkle and Mary Yeaman of Indianapolis, IN, partnered with the Indiana Pacers to host an event that included a Rock Steady boxing demonstration, educational handouts and a reading of a proclamation during half-time. PDF Research Advocate Carolyn Weaver of Freeland, MI, brought posters and informational materials to 13 different locations in her state.
Marian Bumala holding an image of her winning t-shirt design
• Libraries proved to be a great spot for education. PDF Research Advocate Gordie Guist, of Camden, ME, was one of 42 individuals who set up an educational display about Parkinson’s. Supporting the Cure • More than 750 individuals helped PDF to raise $200,000, (well over the initial $100,000 goal) for the Irving G. Brilliant Parkinson’s Research Challenge. Because the challenge met its goal, Mr. Brilliant also increased his matching gift to $200,000, which meant that a total of $400,000 was raised for Parkinson’s research. • PDF Champions held unique fundraising events across the country raising $38,000. In Ocala, FL, Barbara Hebert brought the first Parkinson’s walk to her community and raised nearly $3,000. Barbara Hebert and friends at the first Parkinson’s Walk in Ocala, FL
• Gristedes Supermarkets partnered with PDF in the New York area and raised over $5,000 through the campaign, “Tulips Bloom for Parkinson’s.”
Empowering People | 13
A core component of our mission is ensuring that people with Parkinson’s and their families have the best quality of life. This is only possible when people living with Parkinson’s receive the best possible care. For over 35 years, PDF has offered mentorship programs that provide the training needed to ensure that the best minds are recruited to Parkinson’s research and care. In recent years, PDF has expanded its training programs to include online courses for healthcare professionals serving people with Parkinson’s.
Investing in the Training of Physicians and Researchers Although the number of people living with Parkinson’s is expected to increase in coming years, there is a shortage of the physician-scientists necessary to help not only understand Parkinson’s, but also to carry new discoveries forward into the clinic to help people living with the disease. So how can the best physicians be encouraged to acquire additional training in Parkinson’s disease? PDF focuses on this challenge and invests in the training of physicians and researchers throughout their careers. One of these physician-scientists is Christopher W. Hess, M.D., a Research Fellow at Columbia University Medical Center. During the first two years of his fellowship, Dr. Hess honed his skills in the care of people with Parkinson’s and became interested in researching how the nervous system affects movement in Parkinson’s.
14 | Improving Care
Dr. Hess’s research involves investigating the brain’s ability to “compensate” in Parkinson’s. It turns out that the brain — its cells and the billions of connections between them — shows a limited ability to change and adapt when faced with new experiences, including injury and illness. For example, in Parkinson’s, the area of the brain known as the basal ganglia — which helps to produce the body’s voluntary movements — stops working when it loses dopamine producing cells. When this happens, Dr. Hess speculates that other parts of the brain may lend a helping hand. This means that although the basal ganglia are not working properly, other parts of the brain kick in to ensure that a person with PD initially does not experience any symptoms. In fact, those symptoms might not be noticeable to a person with PD until the time when the brain can no longer help out, or compensate. Dr. Hess hopes his studies may pave the way for better objective tests that could help diagnose Parkinson’s earlier in its course — perhaps even before a person notices any symptoms.
Improving Care
Offering Educational Opportunities to Healthcare Professionals Nurses and physical therapists play a key role in ensuring that people with Parkinson’s have the best possible quality of life. Unfortunately, there is little information on the disease designed specifically for these professionals. PDF believes that offering educational opportunities to healthcare professionals will help ensure better care for people with Parkinson’s. Our free four-part online course, Parkinson's Across the Lifespan: A Roadmap for Nurses, was designed to address this need and provides the latest in current treatments and care strategies. This course is led by Parkinson’s nurse specialists, physical therapists and people with Parkinson’s. Continuing education credits are available. In 2011, more than 4,000 nurses from around the world completed the course. This brings the total number of registrants to more than 9,000 since its
launch in June 2010. This course was designed and hosted by PDF in collaboration with the American Parkinson Disease Association and the National Parkinson Foundation. Building on the success of this course, PDF led the development in 2011 of an online course for physical therapists entitled, Parkinson’s Disease: A Practical Approach to Evaluation and Treatment for the Physical Therapist. This four-part course was designed by expert physical therapists in the field of Parkinson’s and offers updates in best practice for treating people with Parkinson’s. Continuing education credits are available. It was launched in April 2012 by PDF in collaboration with the American Parkinson Disease Association, the American Physical Therapy Association and the Visiting Nurse Service of New York.
“PDF believes that offering educational opportunities to healthcare
”
professionals will help ensure better care for people with Parkinson’s.
The PDF Effect: Annual Report 2011 | 15
A
The work of the Parkinson’s Disease Foundation is only possible because of the generous support of numerous individuals, families, foundations and corporations. PDF gratefully acknowledges the following donors who are central to “The PDF Effect” and who are helping us to improve the lives and futures of people touched by Parkinson’s.
Events that Support PDF In 2011, events that supported PDF around the country grossed over one million dollars for Parkinson’s research. In New York City, almost 1,000 people joined together to support PDF by attending one of our three annual events: Bal du Printemps; Celebrate Spring; and Carnaval at the Copa. In total, these events grossed approximately $750,000. In addition, we were joined this year by over 50 PDF Champions who gave their time and energy to raise awareness of Parkinson's and funds for PDF in A) Herbert Pardes, M.D. and John Thain at Bal du Printemps.
their local communities. These volunteers helped to move the cause forward by organizing pancake breakfasts, joining standup paddle boating events, running in marathons, participating in bike rides and walk-a-thons and by creating their own personalized pages on the PDF website in honor of loved ones with Parkinson's. Their efforts raised almost $300,000. PDF is very grateful for the efforts of its generous volunteers that have made these events possible.
B) Co-chair Amy Sole and friends at Carnaval at the Copa.
H) PPAC Member Tom Palizzi and family who generously replaced their Christmas exchange with a donation to PDF.
C) Co-chairs G. Pennington Egbert III, Missy Egbert Sheehan and Georgina B. Schaeffer at Celebrate Spring.
I) Family and friends celebrate the life of Ernest G. Spence with a New England-style contradance.
D) Rachel Isenberg and Douglas Briller at Mt. Kilimanjaro.
J) John Morris and friend at his Bicycle Across New York State event.
E) Nicholas Tarallo, Belkis Rosario, Jeffrey Miller, Debra Castiglione and Marc Pillinger at the 6th Annual Pillinger Miller Tarallo, LLP, (PMT) Golf Outing.
K) Edward Barsamian, Cornelia Ercklent and Jeffrey Caldwell at Celebrate Spring.
F) Molly Riddick and friends at the Second Annual Pancakes for Parkinson's benefit.
L) Molly Eger and PPAC Member David Eger at the Ninth Annual Music for Parkinson's Concert.
G) PDF Executive Director Robin Elliott, Board Member Margo Catsimatidis and John Catsimatidis at Bal du Printemps.
M) Pam Quinn and Lucy Roucis at Bal du Printemps.
16 | Our Donors
N) Pamela Strom and Susie Prestie at the first Standup to Parkinson's Race.
Our Donors
B C D
E
F
G
H I
J
K
L M N
The PDF Effect: Annual Report 2011 | 17
Our Donors
The following individuals, families, foundations and corporations have made cumulative gifts of $500 or more to PDF between July 1, 2010 and December 31, 2011.
Individuals Colman and Nancy Abbe
Harry Bailey
Arnie Bernstein
Andrew Bookout
Kyle W. Abel
Patricia P. Bailey
Daniel and Shelolia Bernstein
Edward C. Booth
Robert and Georgean Abels
Robert and Barbara Baker
Josh Bernstein
Charles A. Bordner, Jr.
Andrew Abramson
Sharon and William Baker
Richard A. Bernstein
Stephanie E. K. Borynack
Andrew and Danielle Abramson
Alex Balanevsky
Neil and Marilyn Bersch
Patrick and Martha Boudewyns
Shirley Abramson
Thelma and Ray Balbes
Mr. and Mrs. David M. Berwind, Sr. Diana Bouton
Leslie J. Acherman
Byrd and Alice Ball
Morris Berzon
Dierdra Bowditch
Stephen and Marsha Ackerman
Florence Barad
David and Jo Anne Bescherer
Grace Bowman
Carol H. Adragna
Sandi Bartel
Beth Besen
James and Michelle Bowman
Dr. Avadesh and Uma Agarwal
Walter Bates
Latchmin Bharat
David Bradford
Sunil Agrawal
Doris Bato
Mr. and Mrs. Alan L. Bibby
Mary Ann Bradham
Mark A. Ahlemann
Peter M. Bauer
Kevin and Debbie Biddle
Sandra Brawner
Roger E. Ailes
Sandra Beal
Louis Bigliani
Bill and Terri Breach
Mr. and Mrs.Thomas S. Alexander Bill and Diane Allen George and Jodie Allen Janet S. Andersen Eric A. Anderson Janet Anderson Mr. and Mrs. Nigel Andrews Joe Andronaco Eric Appelbaum Salvatore Armenio Daniel Armstrong Jeffrey and Shari Aronson Walter E. Arps Mark E. Arroll Simon Asselin Edgar Astrove Shahid Atcha John and Anne Atherton
John and Virginia Beaman
Andrea Billhardt
Michael and Tracess Brenner
Michael and Marcia Beck
Simran Bindra
Carol S. Brewer
Bernie and Wendy Beiser
Jules and Helen Bingham
Hon. Gale Brewer
Mr. and Mrs. Frank M. Bell, Jr.
Maurice and Sarah Birdwell
Irving G. Brilliant
Janet and Lawrence Bell
Lewis Black
Toby Brimberg
Alfonso C. Bellanca
Page Morton Black
John and Patty Brissenden
Marvin Bellin
James Blackorby
Jill and Ken Brodkowitz
Mark Belotz
David H. and Mary B. Blair
Robert and Judith Brody
Dr. Gardner and Patricia Bemis
Cliff and Arlene Blaker
Doug Brown
Don and Carol Bender
James and Carol Blann
Edward and Karen Brown
Tom and Anne Benedict
Moshe Blich
James S. Brown
Alison Benge
Sean and Rosanne Bloodwell
Michael Brown
Robert Benjamin
Herschel and Rita Bloom
Frank A. Bennack
Theodore and Flora Blumenthal
Dr. Russel and Dr. Susanna Brown
Jack M. Berghuis James and Suzanne Bergoffen Donald Berkowitz Martin Berkowitz
Allan Atmore
Deborah Berman and Bruce Greenberg
Norman and Alison Axelrod
Bernard Berner
18 | The PDF Effect: Annual Report 2011
David and Susan Brunell
James Bobo
Nancy F. Brunetti
John and Barbara Bohannon
Gregory Bruns
Richard Bohlen
Bunyan Bryant
Rose-Marie Boller
Amy and Arthur Buckman
Joan R. Bolling
Mr. and Mrs. Mark Budd
D. R. Booker
John and Mary Ann Bumgarner
Klaus and Robyn Burckhardt
Tom and Shwu Mei Chen
Pamela B. Burgess
Kang Cheng
Daniel and Maureen Cummings, Jr.
Michael Donnantuono Christine A. Doyle
Julie Donovan
Nancy Burke
Terry and Brooke Cheng
Mr. and Mrs. William Cunningham
Dr. Robert Burke and Dr. Sharon Wardlaw
Mr. and Mrs. Thomas Cherner
Gene and Judi Curry
Mr. and Mrs. David A. Dray
Shuet-Hing L. Chiu
Barry Curtis
Lyle Drews
Albert and Vera Chrone
Christopher Curtis
Jennifer Driana
Richard Churchill
John Czarnecki
Chris and Jill Drury
Robert and Patricia Caldwell
Wayne Citrin and Deborah Arhelger
Mr. and Mrs. Stephen D'Amato
Mark and Lorraine Duewiger
Marvin S. Caligor
Carol C. Clark, Ph.D.
Mr. and Mrs. Phillip A. Daniel
Richard and Jane Dunbar
Pete Campbell
Aaron and Wendy Clayton
Philip and Mark Danely, Jr.
Bob Duncan
William R. Campbell
Marlynn Clayton
John Danstrom
Harold Dunlap
Joaquin and Angela Campo
Mary Jane and Carleton Cleveland
Mr. and Mrs. Alex Darragh
Roger C. Dunn
Beverly Dashevsky
David and Carole Ebner
Ralph Cline
Diana H. Davis
Brian and Karen Eckhart
Jean Clovis
Mr. and Mrs. Monty Davis
Hollis and Sharon Eddins
Mark Coatney
Ellen R. De Carr
Arthur and Martha Edelstein
Andrew Cochrane
Elizabeth de Lima
Mark Edie
Dr. William Coggshall
Dr. Linton Deck
Loralee Edlund
Norman Cohan
Thomas Y. Deconcilis
Abbie Edwards
Dayl Cohen
Stephen and Kristine Delay
G. Pennington Egbert III Mrs. George P. Egbert, Jr.
James and Debbie Burrows Judy Buyan Peter and Barbara Bye
James M. Cantrell, Jr. Jeff and Dieta Cao Robert and Mary Capaldi James and Mary Jo Capps Karen Card Sharon Cardinal Peter Cardozo Mr. and Mrs. Raymond W. Carlin
Mendel Cohen
Guido D'Elia
Martha B. Carlisle
Gerard Cole, Jr.
Rance and Donna DeLong
Adele Eger
Lisa L. Carnoy
Maureen Coleman
Cynthia Deluz
David and Jane Eger
Ed Carson
Debra M. Collins
Walter Dennis
Ronald A. Eger
Benjamin Carter
Arlene and Walter Cooper
Deborah DePace
Soral Eglowstein
James and Nancy Casty
Mr. and Mrs. Thomas A. Cooper
Anthony DePaolo
Roberta Ehre
Virginia Y. Detoy
Dr. N. J. Ehrenkranz
Max S. Deutsch
Frances Ehrlich
Brett DeWolfe
Robert Eidelberg
Jerry Diamondstein
Charlotte Einstein
Mr. and Mrs. Chris J. Dicharry
Stafford Elias
Mark Dickinson
Robin A. Elliott and Dr. Sheila Gordon
Lee S. Casty Ronald G. Casty John and Margo Catsimatidis Mike and Joyce Caudill Gregory and Amy Cecchi Mr. and Mrs. Bernard D. Chalfin A. W. Chandler George Chang Robert Chang Robert Chartoff Carol and Stephen Chase Mr. and Mrs. Adam Chasnow Howard and Shiow Ling Chen John and Julie Chen
Dr. and Mrs. Frank J. Coppa Katharine T. Cornelius Arnold S. Corrigan Betty Cotton Norman and Helen Coulson Dr. C. W. Cowles Matthew and Janice Coyle Matthew Coz William Cribbin Sally S. Cross Rev. Carol C. Cruikshank Jose R. Cruz Jennifer Csorba
Ervin Dieckhoff Albert L. Diringer Aida S. Dishman Lawrence Dobrow Gary R. Dodman
Patricia and Daniel Ellis Paul Ellis Ernest Ellison II Samuel and Maryann Ellsworth
Kathleen and Eamonn Dolan Mr. and Mrs. Francis Donnantuono
Our Donors | 19
Our Donors
Individuals James A. Emanuele
Russell Furtick
Mr. and Mrs. Benjamin Gomez
Jon and Stevi Gurkoff
Dr. Renee Epstein
Rose Mary and Dan Fuss
Charles E. Good
Andrew Gustin
Steven and Linda Epstein
Ronald and Kroupa Galowich
Richard Goodman
Lydia Gustin
Mr. and Mrs. Jeffery Ettinger
Sarah Belk Gambrell
Dr. Robert R. Goodman
Mark Guzzi
Ellen Fagan
Alan and Marion Garfield
Sarah Goodman
Lois Gwinn
Dr. Stanley and Charlotte Fahn
Diane Garrett
Preston Goodrich
Dr. Ann Rita Hader
Fernando U. Fajardo
Eleanor Gatto
Verma Goodwin
Scott D. Hahn
Paul Falick
Mr. and Mrs. William R. Geist
Alan L. Gordon
Michael Halchak
John P. Falk
Venita Georgieff
Carol E. Gordon
Jeffrey Hamer
Dr. Andrew Farb
Mr. and Mrs. Daniel Gersen
Mr. and Ms. James A. Gordon
William Hamilton
Kenneth H. Fast
Brian J. Gettleman
Stephen Gorny
Charles Hammer
John Fatteross
Helen D. Gibbons
Norma Hammond
Burt and Noelle Faure
Gerald Z. Gibian
Peter John Goulandris and Dr. Karen E. Burke
Gian M. Favalli
Joel Gibson
Leonard and Gloria Fazio
Nora Gibson
Dr. Daniel Feinberg
Robert M. Gilhooley
Barry A. Feldman, D.D.S.
Christopher Gillock
Mr. and Mrs. Paul Feldman
Anthony and Susan Gilroy
George F. Fesko
Dr. Laura Ginkel
Richard Field
Mr. and Mrs. Myron Ginsberg
Philip Fierro
Robert and Gail Ginsberg
Sheldon Fireman
Don S. Ginsburg
Joseph R. Fisher, Jr.
Catherine Giordano
Mr. and Mrs. John J. Fleps
Betty and Max Glass
Richard Gourdeau Mr. and Mrs. Thomas G. Grace, Jr. Stephen L. Graessle Rachel Granger Dr. Michael and Dena Granhof Christine Grant Patrick J. F. Gratton Helen W. Gray Kent Gray Mr. and Mrs. Alan C. Greenberg Betty Jo Greenberger Sherwin Greenwald
William Haney Sulabha V. Hardikar J. Alan and Karen Harding Katie Harms Gilbert Haroche Nancy Harold Steven G. Harper, M.D. Benjamin and Doris Harwell Diane Harwood Don Haslett Mr. and Mrs. Jeffrey Havsy Russell and Wilma Hawk
Margery Z. Flicker
Carol Glickenhaus
Dr. Ann E. Fordham
Stephanie Gluck
Mr. and Mrs. Alan J. Forman
Morton D. Goetz
Cathy Forsberg
Edythe Gold
Dr. and Mrs. Brian Forst
Nancy Gold
Jack Fortinsky
Michael and Anne Golden
Dr. and Mrs. Edward F. Fox
Stanley F. Goldfein
Patrick Franc
Alvin Goldman
Leonard and Jennifer Gruenberg
Jonathan Franzen
Amy Goldman
Nicole D. Guidara
Michael W. Herlihy
Kristina Fresk
James and Sarah Goldman
William and Ruth Gulick
Margaret S. Herold
Geoffrey and Sarah Gund
Philip C. Herr II
Dr. and Mrs. Lawrence Friedman Stephanie Goldman-Pittel and Andrew Pittel Elizabeth B. Friou Dr. Thomas R. Goldsmith Dr. Paul A. Fuchs Jerome Goldstein Mark Funderburk
20 | The PDF Effect: Annual Report 2011
Mr. and Ms. Nicholas P. Greville Mr. and Mrs. John Scott Griffin Andrea Grillini Pete and Emily Gross Sharon Grossman Lillian M. Grossman-Strater
Jimmie and Kurt Hayek Susan Heidenberg Dr. John and Peggy Heilman Jean Kenna Heins Sydney and Roslyn Helfen Mr. and Mrs. Lewis Helfstein Richard and Rose Henneberger Troy D. Henry
Sharyn L. Gunderson
Mr. and Mrs. Stuart A. Hersch
Arlen R. Gunner
Dr. Daniel and Ms. Natalie Hertz
Shelly Guo
Henry G. Herzing
Raymond Hull
Chris and Marnie Kapuscinski
Joel N. Klevens
Mr. and Mrs. Steven Herzog
Helen C. Hutchison
Gary M. Karlitz
George and Jennifer Heseltine
Mr. and Mrs. Mark Indelicato
George Karnoutsos
Dr. David L. Klionsky and Eva Youshock
Steven and Sherry C. Hibshman
Dianne C. Isenberg
Andrew C. Karp
Cliff Ishmael
Richard and Jane Karp
John Isley
Karoly Kasza
Nancy L. Isserlis
Arnold A. Katz
William and Judith Jackson
Steven Katz
Mr. and Mrs. Alan L. Jacobs
Mr. and Mrs. Lawrence Katzman
John Hickey William and Mary Hicks Richard L. Hildbold Mr. and Mrs. Lane M. Hill Majorie and William Hill Sara Hill Jean Hilton Nancy E. Hinkley Mr. and Mrs. Robert F. Hirsch Anna Ho George Hoberg Bryan Hockman Ian Hodgson Monty Hoeflein Elizabeth and Marvin Hoekstra Robert Hoemeke
Randi S. Jacobs Selwyn and Marjorie Jacobs Denny P. Jacobson Ben Jacoby Peter H. Jakes Allan Janoff Richard N. Jayson Judi Jecmen Mr. and Mrs. Arthur P. Jentoft Dean O. Jeynes Donald and Marian Johnson
Randolph S. Klueger James Knowles Suzanne Knowles Edgar and Eileen Koerner Mr. and Mrs. A. Eugene Kohn Shiro Koike Patricia Kolb
Suzanne M. Kavetas
Isobel R. Konecky
Lori Kay
Mr. and Mrs. Robert Kooiman
Paul Kebabian
Kristijan Kordic
Christopher Keber
Cheryl R. Korth
Judithann C. Keefe
Kay Kowitt
Mr. and Mrs. David C. Kell
Mary J. Kraaij
Dr. David L. Keller
Henry E. Kramer
Mr. and Mrs. Lawrence Keller
Phyllis Kravetz
Edward Kelly
Seymour Kreshek
Kathleen D. Kelly
James Kress
Mr. and Mrs. Robert Kennedy
Midge Kretchmer
Jeffrey A. Hoffman
Kevin P. and Laurel E. Johnson-Smith
Arthur and Nancy Kesselhaut
William Krieg
Mr. and Mrs. Neil Hoffman
Mary Johnson
Fadi Khater
Philip and Mary Hogan
Michael D. Johnson
Mary and Franklin Kilgore
Mark B. Kristof and Beth V. Ward
Stephen and Margot Holland
Rhona B. Johnson
Sarah King
Karen Holmes
Thad and Suzanne Johnson
A. E. Kinnison
Alexander Holtzman
Crandall D. Jones
Kaitlyn L. Kinsey
Katherine Hopkins
David and Carolyn Jones
Linda S. Kinzelberg
Sandy and Bruce Horn
Nathanial and Judith Jones
Clarence Kipps
Mr. and Mrs. Jerry Hornstein
Eleanor N. Jordan
John Kirrane
David L. Horwitz
Robert and Sheryl Josephson
Barbara Kirsh
Andrew and Susan Howard and Family
Rosemary Joyce
Stephen Kish
Leslie Kahn
Nicholas Kissel
Sherrie Kaiser
Kevin Kissell
Andrew Kampf
Dr. and Mrs. Francis l. Kittredge
Daniel and Susan Kane
Andy Klein
Zelma Kangas
Gary M. Kleingartner
Henry Kaplan
Mr. and Mrs. Edward Kleinshmidt
Elmer Hsu Deborah and Alan Huber Harold and Pamela Huberfeld Helen Hudgens Patricia H. Huggard Seth Huhnerkoch
Babette E. Krolik Gloria Kronenberg Mr. and Mrs. Rhett Krulla Carol Kuchar Howard and Gail Kunreuther Howard C. H. Kuo Barbara Kyse Patrick LaGrange Louise M. Lallier Lawrence Lam Gordon Lambert Family of Ann and Scott Landes Nancy and Kenneth Landes and Family
Our Donors | 21
Our Donors
Individuals Robert F. Landy
Joan Lipkowitz
David J. Marx
Milton and Cheryl Mill
Mark Lane
Cara Lipshie
Yvonne L. Mason
Mr. and Mrs. Doug Millar
Merry and Martin Lapidus
Mr. and Mrs. Joseph Liss
Catherine and Allan Mathis
Dr. David Miller
Mr. and Mrs. Manuel Larramendi Mark and Judith Litt
George and Priscilla Matouk
Jody Miller
Robert and Susan Larson
Stephen Littman
Mr. and Mrs. Ray Matra
Kendall L. Miller
Roxana Laughlin
Theresa Lo
William and Gail Mattsson
Michael Miller
Robert O. Laven
William Lockeretz
Diane Matusiak
Richard and Lois Miller
Sarah Le Sueur
Marshall Loeb
William and Natalie Mauskopf
Mark Milstein
Mrs. Gene G. Leary
John T. Loftus
Robert M. Maxwell
Pauline M. Lecomte
Bruce and Priscilla Long
Michael and Jessica Mayerson
Eugene and Barbara Miltenberger
So Young Lee
Mr. and Mrs. Douglas Long
William McAlee
Brian Leffler
Gloria Long
Robert and Marsha McCleary
Suzanne M. Leggett
Jim Long
Mark and Gaby R. Lehrer
Mr. and Mrs. Robert Long
Michael and Cynthia McConnell
Mr. and Mrs. Mark Lehrer
Robert D. Lonier
Thomas Lehrer
Gilbert Louzoun
Mike Lein
Dina Lowy
Jill Leinbach
Anthony and Lillian Lu
Laurie Leiner and Morton Katz
Chris P. Lucas
Walter F. Leinhardt
Joseph and Patricia Luetje
Jeffrey and Penelope Leman
Mr. and Ms. Walter Lyczkowski
Johanna K. Lemlech
Hsiang Lin Ma
Jason Lerman
J. W. and Emily Maallister
Dr. Ilan and Dr. Barbara Levi
Marcia L. Mac Harg
Dina L. Levin
Joanne C. MacCallum
Francine and Irwin Levine
Daniel Maddalena
Jerome and Arlene Levine
George R. Mahoney, Jr. and Linda L. Mahoney
Muriel G. Lewis Constance E. Lieber Anita and Stanley Liebowitz Stanley and Susan Liebowitz Mr. and Mrs. William Lifland John and Catherine Liguori Ruth V. Lilley Betsy Lim Mr. and Mrs. William M. Linden Edward and Sylvia Linhares Richard Linhart
Mr. and Mrs. Burton C. Mallory Larry and Janis J. Malone William and Catherine Mandi Ellen H. Manian On-Hou Mar Sidney and Phyllis Margolis Linda Markeloff Rebecca Markley Kay Marmorek Lucille Marquez Sharon R. Marr
22 | The PDF Effect: Annual Report 2011
Everett McCubrey Erin McGarry Cubero Charles McGeown John and Helen McGrath Kevin M. McHugh Dr. Guy McKhann Gordon McLean Charles A. McMellon John P. McMichael Molly McMillan W. McMillin Claire A. McNary
Christina Milton Carol M. Miner Marion and Walter Minton Dr. Martin Mintz and Ms. Cynthia Mintz Alan B. Mirken Zareen Taj Mirza Lawrence J. Misrok Dr. Ena E. Mocega, M.D. Gina Modica Gretta and Lee Mogel Andrea Moletteri John P. Molloy, Sr. Louis Monaco, Jr. Donna Mondani Elena Mondini Christopher Montgomery
Mr. and Mrs. Stephen J. McShane
Jan M. Montgomery
Mary J. Meehan
Mr. and Mrs. George E. Moore
Jane Meeker
Mr. and Mrs. Robert E. Moore
David Melillo
Mr. and Mrs. David Moorman
Merle D. Melvin
Miriam Moran
Dr. Vincent Memoli
Howard and Ginger Morgan
Andrew and Brigittar Menard
Peter A. Morgan
Dr. Robert Mencher
Florence Morris
Robert and Kathleen Menifree
Jay B. Morrow
Craig A. Merdian
Pam Moshe
S. W. and Joan Metcalf
Steve Mount
Joseph W. Metz
Paul V. Mrugacz
Irving G. Brilliant Research Challenge Supporters We thank these contributors to the Irving G. Brilliant Research Challenge 2011 who gave $500 or more and whose gifts were matched by Mr. Brilliant for a total of $400,000 raised for Parkinson's research. Thelma R. Balbes
Majorie and William Hill
Monica Reed
James and Suzanne Bergoffen
Eleanor N. Jordan
Stephen Reed
Rose-Marie H. Boller
Light of Day Foundation, Inc.
Ezra and Nilofer Reese
Irving G. Brilliant
Mark D. Litt
Henry Richmond
Mr. and Mrs. Mark Budd
Burton Mallory
Sherie Ritzler
Robert Chartoff
Ellen H. Manian
Christopher Rohwetter
William Cunningham
Andrew Menard
St. Jude Medical Center
The DuBose Family Foundation
MetLife Alico
Stan M. Sandberg
Bob Duncan
Joseph W. Metz
Paul Ellis
Marion Minton
Arnold and Marie Schwartz Fund
Epstein, Becker & Green, P.C.
Andrea Moletteri
Ferguson Family Trusts
Sunil Nayar
John W. & Laura S. Stewart Foundation
Ronald H. Galowich
Robert Northington
Rebecca C. Swan
Stanley F. Goldfein
Dorothy S. Oda
Martin Typer
Preston Goodrich
Rick Oddo
U.M.R. Foundation
Wilma P. Hawk
John and Marnie Olson
Mark Viviano
Clyde W. Smith
Michael Opalak
Diane M. Mueller
Maggie Nicholas
Terrence C. O'Bar
Michael Opalak
Kenneth N. Munsen
Pearl Nicholls
Bernice S. Oberndorf
James Orsini
Mr. and Mrs. Michael Murphy
Magda Nieuweboer
Mr. and Mrs. George O'Connor
Neal Ortenberg
Elizabeth Murray
Sally L. Nightingale
Thomas and Dorothy Oda
Debra Osburne
Kenneth Musen
Agnes Nixon
Rick Oddo
Mila A. Ostin
Frances F. Musser
Jim and Marla Nock
Debra Oden
Don Oswald
Jean Myers
Edward J. Noha
Robert Ogden
Melissa Nace
Lloyd Noland
Kathleen O'Grady
Mr. and Mrs. Robert Paglia and Family
Sarita Narson
Robert Northington
Christopher and Lilla Ohrstrom
Paul and Marcy Nathan
Sabato Noto
Carol Okane
Sunil Nayar
Allan Novak
Aksel Olesen
Douglas C. Nelson and Jean A. Douglas
Mr. and Mrs. Eugene A. Nowell
Donald Olson
Carol Noymer
John and Marnie Olson
Mr. and Mrs. Lawrence C. Nussdorf
Mr. and Mrs. Timothy Onders
Ruth K. Nelson Bernard and Sandra Newman
David and Judy Pahren Arthur Palik Tony Pallagrosi James Palmer Dr. Pasqual J. Pantone Blaine Parkin and Maralee Chase Parkin
Our Donors | 23
Our Donors
Individuals Alan Patricof
Frederick Prince
Dawn Roberts
Hellyn L. Sarek
Hugh L. Patterson
Ronald D. Provost
Mr. and Mrs. Jeffrey D. Roberts
Lawton Sargent
Randall and Mary Payne
Dana C. Puddy
Thomas and Brenda Roberts
Scott Sassa
Sandy Payne
Bhaskar Pulikal
David Robinson
Melba Pearlstein, Esq.
The Roland T. Quade Family
Sally Robinson
Mr. and Mrs. Gary Satterthwaite
Dr. and Mrs. Timothy Pedley
Marjorie Quaife
Dr. Jean-Christophe Rochet
Deborah Pelle
William Rabbe
Karin Rodgers
Val R. Pemberton
Mickey and Ellen Rabina
Hazue T. Rogers
William S. Penick
Jeffrey Rabinowitz
Fritz Rohrlich
John C. Pepples
W. Matt and Amelia Ralls
Christopher Rohwetter
Shirley Perez
Gerald and Barbara Ranzal
Robert and Heddie Romanoff
Theresa D. Perl
Cathy Raphael
The Romero Family
Dr. Carolyn Perla
John Raphael
John Rosecky
Harvey and Irene Pessar
Debra Raskin and Michael Young
Mark Rosen
Dr. Neil Schiff and Patrice L. Schiff
Charles A. Rosenbaum
Keith E. Schilder
Mr. and Mrs. Frank A. Petitti George Petras Col. and Mrs. John Phelps
Michael and Kristin Reed Dr. Monica Reed and Stanton Reed
Eleanor and Richard Phillips
Stephen Reed
Stephen and Patricia Pickering
Mr. Ezra and Dr. Nilofer Reese
Donna Pickett
Ralph and Barbara Reis
Colin G. Pitt
Aleks and Stacy Renshaw
Nina Platt
David and Nancy Resnick
Carol Pogash Marilyn J. Polansky
Andath L. Saunders Daniel C. Savitsky Anand R. Savur John and Deborah Scanlon Mr. and Mrs. David S. Schaefer Donald A. Schaefer Heather Schaefer Matthew J. Schaeffer
Jean Rosenberg
Susan Schindler Mr. and Mrs. Edward Rosenblum Steven Schirripa Carol Rosensweig and John Schlarbaum Charlene D. Grant Dr. Gregory and Melvin S. Rosenthal Patricia Schlegel David and Nadine Ross Dr. Herbert Schlesinger Dr. Harley A. Rotbart
Carole Schlessinger
Dr. Margaret E. Rice
Dr. Deborah C. Roth and Jack Roth
Robert E. Schmitt
Harold V. Richard
Melissa Roth
Anthony and M. Allison Richards
Mr. and Mrs. Steven Rourke
Richard and Anita Pollak Ruth Pollack and Martin Bressler
Paul and Tanako Richards
Deborah Pollard
Henry and Renee Richmond
Sheng-Shung Pong
Mr. and Mrs. Alan B. Richstein
Carlyn G. Poole
William and Sandra Richter
Mr. and Mrs. Henry A. Pope, Jr.
Drs. John and Susan Pollack
Dr. and Mrs. Lewis P. Rowland Robert Rozak
Fredrick and Karen Schneider Marriane Schnell Jay and Suzette Schochet Charles and Kathren Schreck
Hedda Rublin
Dr. Thomas J. and Jean Schreiber
Carl Russell
Michael Shrimmer
Mr. and Mrs. Michael A. Riddick
Ken W. Ryder
Mr. and Ms. Craig Schrock
Jamie Saccardo
Shelley and Blair Schrum
James and Sandra Porter
Sandra L. Rigopoulos
David M. Schuld
Louisa and Henry Porter
William F. Ringier
Mr. and Mrs. Paigualina Sacchetti
Margaret Posthumus
Frank Ritchey
Ruth Ann Potts
Sherie Ritzler
Dr. Matthew Power Arjun Prabhu
Drs. Lawrence J. and Carol L. Rizzolo
Jack and Pamela Preston
Brenda G. Roberts
24 | The PDF Effect: Annual Report 2011
Steven B. Sadler Albert and Jane Safer Saul M. Salka Stan M. Sandberg and Stacey J. Mayesh David Sands
Brian and Kathy Schultz Eric Schwartz Howard and Phyllis Schwartz Marie D. Schwartz Martin Schwartz Max and Nancy Schwartz
James Parkinson Legacy Society We thank these members of the James Parkinson Legacy Society who have included PDF in their estate plans or have established a charitable gift annuity with us. Gertrude S. Bell
Matilda Goodman
Mr. and Mrs. Robert W. Smith
Roger M. Bowman
Eleanor N. Jordan
Charles L. Thomas
Ann Cavalli
Annette Korn
Lucy Veneble
Aila G. Dawe
Viola B. Marshall
M. R. Weingardt
Jean Dewdney
Edith Perman-Allen
James B. Wittrock
Guy Estes
Marie D. Schwartz
Elizabeth A. Geiser
Stephanie and Bernard Schwartz
If you have made estate plans which include PDF or wish to establish a charitable gift annuity which provides you with income for life, please contact Eddie Pelto, Director of Development, at (800) 457- 6676.
Dr. Regina Schwarz and Dr. David Aftergood
Dr. and Mrs. Thomas Shiftan
Dr. and Mrs. Bernard E. Small
Alice M. Starr
Gary I. Shimoda
Alexa Smith
Roger and Marianne Staubach
Mr. and Mrs. Frederick Schwarzmann
R. L. Shoemaker
Clyde W. Smith, Jr.
Carolyn Stearns
James and Susan Show
James Smith
Carol Stegink
Thelma J. Scott
Rose L. Shure
Kathryn Smith
Joel and Kathy Segall
Stanley Sidel
Steve Smith
Dr. Philip Stein and Bonnie Stein
Ethel Seife
Ms. Janice Siegel and Dr. Lloyd Marks
Mr. and Mrs. Marcellus Snow
Ethel L. Schwarzman
B. Semmel Edward and Cynthia Seretan Dr. William D. Severinghaus and Mary C. Severinghaus
Arthur and Dr. Sandra Siler Julie Silva David Silverman
Mr. and Mrs. Paul W. Snyde, Jr. B. Robert and Mary A. Snyder Glenn Snyder
Rita R. Steinberg Gail Stelter Jonathan and Sydney Stern Louis and Freya Stern Russell and Meryl Stern
Paul Silverman
J. Clifton Snyder and Lillian Gordon Snyder
Brenda M. Shapiro
Mr. and Mrs. Mark K. Silverstein
Amy Sole
Todd D. Stewart
Jerome Shapiro
Robert and Kathleen Simione
Dr. Stanley Sollie
Mr. and Mrs. Abbott Stillman
Leslie C. Shapiro
Ian Simmonds
Dr. and Mrs. Marvin Solomon
Ronald and Evelyn Shapiro
J. Robert and Linda Sims
Phyllis Sonnega
Dr. Alvin M. Stinson and Annette Stinson
Candy G. Shaw
Phillip S. Sirianni, Jr.
Douglas Spaniol
Rev. F. Barry Stipp and Colette Stipp
Felice K. Shea
Samuel J. Sirota
Stacie Spector
Scott Strickland
Dr. Sam Shelanski
Arline B. Slepoy
Sue Sperger
Warren and Frances Stricoff
Debbie J. Shepherd
Catherine Slivinske
Jerry I. Speyer
Richard Strobel
Roger and Ewanna Sherburne
Jeffrey Sloan
Joseph and Louise Spiezio
John Sheridan
Mr. and Mrs. Richard Sloan
Earl and Dolores Spurrier
Christianna L. Strohbeck and Dr. Ramaswamy Murari
Jack and Paula Sherman
John F. Slusser
Matt and Barbara Stanek
Lindsey Strubhar
Douglass and Julie Shands
Sandra and Evan Stern
Our Donors | 25
Our Donors
Individuals Alberto and Lynda Ann Strulovic Francine Turk
Evelene Wechsler
Pamela Yin
Yves T. Struye
David and Sharon Turner
Audrey and John Wee
Beverly Yoder
Jessica Stuart
Martin Typer
James M. Weichert
Susan and Nathan Yost
Christopher and Mary Jo Studwell
Dr. Richard and Gail Ullman
Kenneth and Susan Weil
Jeanne Young
Rodolfo Urbina
Andrew Weinrich
Larry Young
Sharon Sturges Laura Sudar Vivian and Charles Sukenik Anthony and Sylvia Summa Ram and Preethi Sundaram Rebecca C. Swan James and June Swartz Edward and Nancy Sweeney Diane Swonk Kevin V. Symmons Laura J. Taff Charles Talcott James and Mary Talmage Gordon Tannura Catherine Targowski Carol and Melvin Taub Mary Elizabeth Taylor Michael Tedesco Louis Teitelman and Family Nathan and May Teitelman Rocky and Cindy Terrel John and Carmen Thain Ann Thompson
Johanna M. Utrecht
Herbert and Judith Weintraub
Peter M. Young
Lester and Antonette Vaccari
Sally W. Weintraub
Kathy Younkins
Louis Vaccaro III
Mr. and Mrs. Bernard W. Weiser
Pat Younts Lou and Gail Zaccheo
Russell and Whitney Van Nuis
Beverly Weiser
Leslie Van Meir
Dr. James Weiss
Jed and Brenda Zachs
Benjamin and Deborah Varat
John Wellsandt
Edward Zajac
Craig Varrelman
Delores E. Westphal
Rose Zaretsky
Mr. and Mrs. Jeffrey D. Varsa
Nancy M. Wheeler
Christine Zeisler Mr. and Mrs. Robert Zelnick
Yvonne Vasicek
Jennifer and Robert Wheelock
Marshall Vass
Lawrence E. White
Mr. and Mrs. Robert M. Zemsky
Richard N. Vaughan
Pamela White
Judy Zendell
Mary Ann Veitch
Mary Wiebke
Louis G. Zimmerman
Renzo Vescio
Robert and Sherry Wiener
Cynthia Zirinsky
Edward M. Vietor
Robert and Carol Wilder
Melvin and Esther Zirkes
Joseph Virgilio
Jeffrey and Lise Wilks
Donald and Lynn Zucker
Mark Viviano
Kenneth and Kimberly Williams
Susan Zwick
Frederick and Toni Von Zuben
Wendy Williams
Matthew and Sonja Vorwald
Dr. Philip J. Wilner
Jules and Florine Wachter
Kenneth R. Wilson
Richard and Cheryl Wade
Belinda Windsor
Doris C. Wages
Dorothy Winkey
Mr. and Mrs. Alan S. Waldenberg Michael Witter Dan Walsh
Joel Wojnilower
Regina Wang
Adam Wolfberg
Melvin and Charlotte Timm
Mary Wardell
Ann Wolfe
Mr. and Mrs. David Timony
Audrey Warfield
Eve Wolff
Zane G. Todd
Sandi Wasch
Fred and Mary Woodlief
John and Patricia Toebe
Lori L. Wasserman
Rosalind Woolf
Maureen Tokar
Toshi Watanabe
Walter E. Woolsey Dave Wopat
Mr. and Mrs William S. Thompson
Mr. and Mrs. David Tolli
John W. Watkins
Rhonda Tomashefsky
Eliot R. Wax
Terry and Karen Wright
Alison Torres
Betty Weber
Jerome and Selma Yaguda
Marshall and Gloria Tucker
Jane and James Webster
Yi Tien Yang
26 | The PDF Effect: Annual Report 2011
PDF Champions We thank our PDF Champions whose efforts from July 1, 2010 to December 31, 2011 helped us fund promising research and also raised awareness in communities around the US. 3 4 Fighting PD
June Keszeg
Alethea Bancale – Niagara Falls
James Knowles
International Marathon
Diane Banks – Sycamore Hills Golf Fundraiser
Natasha Brown Tomee Brown Gary Chard – Gary's 60th Birthday Party Matthew Coz – Burning River 100 Mile Endurance Run
Lindsay Borsack Cruz – More Magazine Fitness Half Marathon
Tammy Kozumplik – Cut-a-Thon Ivory Latta – 1st Annual Ivory Latta Celebrities for Parkinson's
Adrienne, Peter and Miranda Lee Rachel V. Loeser
Molly Riddick – Pancakes for Parkinson's Benefit
Teresa Riffle – Circleville, OH Walk for a Cure
Michael Roush – Parkinson's Walk for a Cure/In Memory of Lloyd Roush
Frank Rumoro – 1st Annual "Stepping Out" Fundraising Walk
Jill Markey – Doug's Wild Ride
Wendy A. Schreiber
Julee Masters – Cakes Creations and Co
S. Jane Schrick
Charles F. McGeown – McGeown Golf
Michael Showstead – Phillips Boston
Tournament
Banquets
Jason Davis – Bill Lowery Memorial Fund
Kayla McKibben – Dancers Who Care
Julie Silva – San Francisco Half Marathon
Brian DeFord – DeFord Mountain Hike
Kristian Melby – NYC Marathon
Angela Sipes
Maria De Leon, M.D.
David P. Melillo – Zwick Pro Am Golf
Kathy Smith – Change for Parkinson’s
Cindy DeLuz Deana DeModena
Tournament
Jesus John Scott Michael – Poker for Jesus
Megan Smith Bella Somelofske – Newport, RI Marathon
Brett DeWolfe – Iron Man Challenge
Greg Mocarski – Running for Faye
Linda Spence – Ernie's Favorites
Naomi Diep
John Morris – Bicycle from Montauk
Mel Stewart – Cape Epic
Theresa Donahoe John D'Onofrio David J. Eger, Ph.D. – Music for Parkinson's Research
Point to Niagara Falls
Lori Morrow – Chicago Marathon Paul V. Mrugacz – Chili Cook Off Denise Mullineaux
Jeni Forshier-Jenkins – Shuffle and Shake – Parkinson's Awareness
Jennifer Neathery – Neathery Nashville
Ashley Garrett
Tom Palizzi – Tom Palizzi and Family
Antoinette & Ken Geraci Linda Giorgilli-Rice John Gollisz
Marathon Holiday Giving
Parkinson's Support Group of the Mid-Hudson Valley Inc – Walk Over the Hudson
Pamela Strom – Stand Up to Parkinson’s Race
Danielle Surace – Vincent Fillingeri Memorial
Carol Tahsuda Pillinger Miller Tarallo, LLP Cynthia Taylor Doris Vasquez K. C. Veitch – Kappa Delta Phi Sorority/ Sigma Pi Fraternity
Alexandria Gorski – Gorski PD Month
Marina Parrish
Linda Walsh – Run In Honor of Dad
Andrea Grillini – Car Wash For PD
Jim Patterson – Pints for Parkinson’s
Emily Walter
Hillary Hackett – Wake Forest Run/Walk
Crystal Penney – Wedding of Crystal
Madelyn Weingart and Alison Magistrali
in Honor of Uncle Barry
& Tom
Jay Hebert – Parkinsons In the Park
Rita Peters – Oklahoma City Marathon
Clayton Henderson Memorial
Lisa Piccirillo
Michael Hornung – Splash for a Cause
Debra Pinon
Rachel Isenberg – Half-Marathon
Tanya Puckett – Albany, GA Marathon
Philadelphia; Pittsburgh to Philly Bike; Mt. Kilimanjaro Climb
Randi S. Jacobs
Deb Rabinowitz – Every Day Sundays with Mollie
Becky Jarnagin
Alexander Ranieri and Kristina Mazzone – Long Island Half Marathon
Elizabeth Keshish
Don Rempher – Hiking the Pacific Coast
Brittany West – Find a Cure in Our Lifetime
Gillian Woods – Keeping the Pace with PD: NW Arkansas
Yacso-Meyer – Stuart Meyers Champions Event
Pat Younts – Pat Younts Versus Parkinson's Golf Tournament
Zogsports – Zogsports Play for a Cause
Our Donors | 27
Our Donors
Foundations/Corporations/Organizations A&M Label
BlackRock Kelso Capital
Abbott Laboratories
The David H. and Mary B. Blair Charitable Fund
ADM Information Services Kenneth Aidekman Family Foundation
BNSF Foundation TX
Louis and Virginia Clemente Foundation, Inc.
Eli Lilly and Company Foundation, Inc.
The Clorox Company Foundation
Encana Oil and Gas (USA), Inc.
The Betsy and Alan Cohn Foundation, Inc.
Epstein, Becker and Green, P.C.
Epic Systems Corporation
Employees Community Fund of the Boeing Company The Shana Alexander Charitable Foundation Bonner Family Private Foundation, Inc. Alexandra and Martin Symonds Foundation, Inc. Booz | Allen | Hamilton
Jerome and Ilene Cole Foundation, Inc.
Ernst Foundation, Inc.
The George Coleman, Jr. Foundation
The George and Jodie Allen Charitable Fund
Arthur and Eve Fastenberg Philanthropic Fund
Bowman, Monaco and Black, PC
Simon and Eve Colin Foundation, Inc.
Ferguson Family Trusts
Bristol-Myers Squibb Company
Colligas Family Markets, LP
Feuerring Foundation
Brookhill Planning, LLC
The Color Fund
Fidelity Charitable Gift Fund
Brooklyn Mechanical Corp.
Columbia University Medical Center
Firstgiving, Inc.
Brown Charitable Foundation
Community Health Charities
Amicus Therapeutics
BT Americas Corporate Matching Funds
Consumer Electronics Association
Forest Family Foundation
Apple Matching Gifts Program
Budwitz and Meyerjack, PC
Cox Communications
Applied Materials
Burgundy Foundation, Inc.
The Connie Frank Foundation
CSX Corporation
Archer and Greiner, P.C.
The Caliban Foundation
Fred Siegel Foundation
AT+T United Way
California Community Foundation
Cumberland Community Foundation, Inc.
The Fremont Foundation
Edna Williams Curl and Myron R. Curl Endowment for Parkinson's
GE Foundation
Allstate Giving Campaign The Allyn Foundation, Inc. Altria Matching Gifts Program American Society of Appraisers America's Charities
The Atmos Foundation Automatic Data Processing, Inc. BAE Systems The Bane Foundation Bank of America Bank of America United Way Campaign Bart and Associates, Inc. Alvin H. Baum Family Fund Beck and Masten Buick-GMC, Inc.
Boucher Charitable Foundation
Cambrex Corp. Campbell, Inc. Canata Family Foundation
The Dana Foundation
DCH Montclair, LLC D/B/A Cardinal Engineering Associates, Montclair Acura Inc. Diamantine Family Foundation, Cardinal Health Foundation Inc. Caribbean Enterprises, Inc.
The Dinan Family Foundation
Castle Harlan, Inc.
Eamonn and Kathleen Dolan Charitable Fund
James and Nancy Casty Charitable Foundation Lee S. Casty Philanthropic Fund
Don Ayers Pontiac
Fairchild Martindale Foundation
Harriet Ford Dickenson Foundation Fox Family Charitable Trust
Gap, Inc. Giving Campaign General Electric Co. Give With Liberty Ruth and Jack Glantz Family Foundation Inc. Glickenhaus Foundation Joseph H. Goldberg Family Foundation Edward and Marjorie Goldberger Foundation Goldman Sachs Gives Sol Goldman Charitable Trust
The Bendheim Foundation
Ronald G. Casty Family Foundation
The Dopkin-Singer-Dannenberg Foundation, Inc. Dorf Associates
The Berner Charitable and Scholarship Foundation
Cedar Grove Lutheran Church
Google Matching Gifts Program
Dreiseszun Family Foundation
Cemex Materials, LLC
The DuBose Family Foundation
The Samuel and Grace Gorlitz Foundation
Check Point Software Technologies
Dupont Systems, Inc.
Lee Gottlieb Fund, Inc.
Eagel Sports Promotions, Inc.
The Gottwald Foundation
Echlin Foundation
The Tom and Bonnie Grace Family Foundation
Bell-Mark Sales Company, Inc.
Big Y Foods, Inc. Biotechnology Industry Organization Bisgeier Family Foundation Page and William Black Foundation
Terry Cheng Gift Fund The Cimino Group, Inc. Citizens Bank
28 | The PDF Effect: Annual Report 2011
El Paso Corporation
Gracie Square Hospital
Grand Council of Cryptic Masons
Dr. Rudolph and Mildred Joseph Foundation
William and Nancy Lifland Fund
Grand Chapter O.E.S.
Just Give
Light of Day Foundation, Inc.
Mabel Burchard Fischer Grant Foundation
Greater Kalamazoo United Way
Litterman Family Foundation
The Kandell Fund
Loeb and Loeb, LLP
Jerome A. Kaplan and Deena L. Kaplan Family Foundation, Inc.
Lovinger Family Foundation
Sally Nightingale Charitable Fund
Macquarie Bank, LTD MAERSK, Inc.
H&R Block
Fred Kassner Family Foundation
Nine Thirty Capital Management, LLC
The Gwendolyn HalseyAlbertson Foundation
Kastle Greens Corp.
Ann S. and Albert L. Maltz Foundation
Eugene and Emily Grant Foundation The Jack Webster Grigsby Foundation
Harrah's North Kansas City, LLC
Robert and Florence Kaufman Foundation, Inc.
George W. Harris Foundation
Harry L. Kavetas Family Fund
The Harte Auto Group
Kelly Refrigeration and Freezer, Inc.
Mahoney Donor Fund
Mar-Ber Development Corp. Mazur, Carp, Rubin and Schulman, P.C.
New York Presbyterian Hospital The New York Times New York University New York Yankees Foundation
Employees Charity Organization of Northrop Grumman Northwest Hills Credit Union Northwoods League Foundation
McCormick Company, Inc.
The Calvin Flavia Oak Foundation, Inc.
Kelly Family Foundation
The McGraw-Hill Companies
Thomas P. and Patricia A. O'Donnell Foundation
Leona M. and Harry B. Helmsley Foundation, Inc.
Kesselhaut Family Foundation
Medtronic, Inc.
Elmer P. Kinnamon Trust
Office Automation Systems
Merck Partnership For Giving
HighVista Strategies, LLC
The Richard E. and Marianne B. Kipper Foundation
Ogden Cap Properties, LLC
MetLife Alico
OH Local
Sam W. Klein Charitable Foundation
Microsoft Giving Campaign
Richard and Harriet Orkand Charitable Fund
Hauser Family Foundation, Inc. The Hearst Corporation
IHS Foundation Homestead Foundation, Inc.
Sharon Klein Graphic Design
Mid-Atlantic Center for the Performing Arts
Kniffin Family Foundation
Midstate Radiology Associates, LLC
Regina Pargament Trust Fund
The Kortschak Family Foundation
The Millison Foundation
Parkinson Network of Mount Diablo
The Kosher Nosh
The Mirapaul Foundation
Parkinson's Unity Walk, Inc.
The Kraus Family Foundation
Jeffrey Modell Foundation, Inc.
Isermann Family Foundation
Seryl and Charles Kushner Family Foundation
Morgan Stanley
Hyman and Bessie Passman Family Charitable Foundation, Inc.
Isidore C. Myers-Joseph A. Erickson Properties, Inc.
Latham and Watkins, LLP
Mount Sinai Hospital
Lawrence Livermore National Laboratory
Nanell Foundation
Hortley G. Leblang Charitable Trust
Thomas Neal Foundation, Inc.
Honeywell International Charity Matching Gift Program IBM Employee Services Center Independent Charities of America ING Charitable Giving Program Ipsen
The JCT Foundation J. M. Smucker Company Jacoby Family Fund
Motorola Foundation
National Sound Industries, Inc.
PEC United Charities, Inc.
Patton Holdings, Inc. PBM Products Pearson Education Pfizer Foundation Matching Gifts Program
The Janus Foundation
Legatus Foundation
The Netter Foundation, Inc.
Pfizer, Inc.
Jewish Communal Fund
Dana and Jesse Lehman Foundation
Network Consulting, Inc.
PG&E Corporation
John Wojtowicz, Inc.
Network For Good
The Eileen and Peter Lehrer Family Foundation, Inc.
The New York Community Trust
Philip Holzer and Associates, LLC
Anita and Stanley Liebowitz Fund
New York Life Insurance Company
Johnson & Johnson Family of Companies Jordan Family Foundation
The Phillies Davis Phinney Foundation
Our Donors | 29
Our Donors
Foundations/Corporations/Organizations Pillinger Miller Tarallo, LLP
S&S Realty
Suplove, Inc.
Pitney Bowes Employee Giving Program
SAD Foundation
Henry and Marilyn Taub Foundation
Play For Your Cause The Bernard Plotkin Fund The Portmann Family Charitable Fund Premiere Paddle Surf
Edmond J. Safra Foundation Sanky Communications, Inc. Schering-Plough The Jean and Thomas Schreiber Philanthropic Fund
Shirley Waldbaum Witkin Foundation, Inc. Wasily Family Foundation
Judy and Warren Tenney Foundation
Weiden Schwartz Fischler Family Foundation
The David Tepper Charitable Foundation
Weill Cornell Medical College
Teva Neuroscience, Inc.
J. Weinstein Foundation, Inc.
The David C. and Jeannie Price Fund
Schulte Roth and Zabel, LLP
Three Swallows Foundation
Wellpoint Associate Giving Campaign
Schwab Charitable Fund
Prince Charitable Trusts
Phyllis and Howard Schwartz Philanthropic Fund
Timber Creek Capital Management, LLC
Wells Fargo Community Support Campaign
Tishman Speyer Properties, LP
Wellspeak, Dugas and Kane
Quadel Consulting Corp. Qualcomm Matching Gift Program R.A. Novia and Associates, LLC R.C. Bigelow, Inc. Ralph J. Duffie, Inc. Razoo Foundation Red Apple Group Kristin and Michael Reed Family Foundation, Inc. Regions Morgan Keegan Trust The Donald Reich Family Charitable Fund Re-Steel Supply Co., Inc. Retired Public Employees Association of California
Arnold and Marie Schwartz Fund
TJM Investments
WESTAT
Secure Real Estate Management, LP
Toshiba Business Solutions
Westchester Hills Golf Club
Truist
Mark and Muriel Wexler Foundation
Semmes The Shafir Family Fund Leslie C. and Leonard A. Shapiro Family Foundation, Inc. The Ron Shapiro Charitable Foundation
The Trukenbrod Family Foundation Tumi, Inc. Turnaround Management Association UCB, Inc.
The Shubert Organization, Inc.
Richard and Gail Ullman Charitable Fund
Siegel, O'Connor, O'Donnell and Beck, PC
The Ullmann Family Foundation
The Sierra Fund The Oscar and Edith Simon Foundation
U.M.R. Foundation United Refining Company United Technologies
The Herbert and Arline Slepoy Charitable Fund
United Way of Central Indiana, Inc.
Smith Haven Ministries, Inc.
United Way of New York City
Society of the Transfiguration
United Way of Rhode Island
Ropes and Gray, Inc.
The Spurlino Foundation
United Way of Somerset County
Eli and Mae Rosen Foundation
St. Irene's Philoptochos Society
United Way, Inc.
Joseph Rosen Foundation
St. Jude Medical Center
U.S. Charitable Gift Trust
The Benjamin M. Rosen Family Foundation
Frank and Domna Stanton Foundation, Inc.
The V & L Marx Foundation
Rheem Manufacturing Company The Andrew and Lisa Rodman Foundation
The Irene Herbert Ross and John W. and Laura S. Stewart Harper Grant Ross Foundation Foundation Ross-Kolmerten Fund Royal Neighbors of America Dianne H. Ruthman Family Foundation
Vanguard Charitable Endowment Program Visa Givingstation
The Dorothy Strelsin Foundation
Vision Equities, LLC
Sullivan and Cromwell, LLP
Wachovia
Sullivan Solar Power
30 | The PDF Effect: Annual Report 2011
The Wheeler Family Foundation WithumSmith + Brown The Yaspan Unterberg Foundation, Inc. Zankel Charitable Lead Trust Mary and George H. Zimmerman Foundation Zoe's Best Friend, Inc.
Planned Giving Estates
Planned Giving Trusts
Succession of Verble Mary Augustine
Isabellea M. Amell Revocable Trust
Joseph M. and Eva M. Perasso 2000 Trust
Gloria Broward
Evelien Auerhamer Trust
Powers Revocable Trust
George Bruno
Adele Blank Charitable Lead Trust
Elizabeth Kellogg Crouch J. B. Daiches
Dorothy M. Booth Charitable Trust
Richard P. Rost Trust Esther Ruddick Trust Frances Marie Smith Revocable Living Trust
Nelson C. Doland, Jr.
BettyLou Burton Trust
Lillian Dursht
Mae C. Clegg Trust
Ernest C. Geiger
Ruth D'Atri Trust
Lester W. Stevenson, Jr. Trust
James C. Harnden
Trust of Edith Eisler
Esther Stykel Living Trust
Ruby Jefferson
Lida Ferguson Testamentary Trust
Esther Wright Trust
Dorothy Bauer Jochem Anthony Klempa
Gladys Field Charitable Lead Annuity Trust
Dolly Koler
Dorcile R. Fowler Trust
Marie Langlois
Evan A. Fradenburgh Trust
Kenneth W. Law
Millie & Jesse Fusfeld Charitable Trust
Virginia N. Lowry Irene M. Matto Appolonia Mayer
Bettie D. Gallagher Irrevocable Trust
John D. Mazzarella
Annette Goodrich Revocable Trust
Paul Edwin Melcher
Hudson Charitable Trust
Joan P. Metcalf
Gladys T. Hyman Trust
Velma R. Nagel
Charles Irwin Trust
John J. Robinson
J. Bert Jones Trust
Anne J. Schaff
Rose A. Kalns Trust
Florence Schwartz
Kniffin Charitable Remainder Trust
Helen Sisko Lawrence Stchur Martha Valchich Irene A. White Allyne Whitlock M. R. Wiegandt Edward Zotter
Wesley L. Southerland Revocable Living Trust
Trust of Virginia Ladensohn Toni Lieberman Family Charitable Trust Margaret D. Lienemann Charitable Trust Irene M. Matto Trust Gordon McLean Trust Trust of L. M. McOmie Henry A. Morris and Marian C. Morris Revocable Living Trust The Melba M. O'Connell Trust
Our Donors | 31
In 2011, PDF awarded $5.5 million for Parkinson’s research. This included 40 awards for projects and mentored fellowships initiated by individual investigators from the global scientific community and collaborative projects conducted by research teams at major institutions. We thank the following grant recipients for their commitment to improving the lives and futures of people touched by Parkinson’s. Center Grants | $2.62 Million
International Research Grants | $825,000
Allow talented scientists the flexibility and long-term support to collaborate on basic, translational and clinical research.
Promote innovative research projects that have high potential to significantly advance the knowledge of Parkinson’s.
Columbia University Medical Center Roy N. Alcalay, M.D., Robert Burke, M.D., Lorraine N. Clarke, Ph.D., Stanley Fahn, M.D., Blair Ford, M.D., Lloyd Greene, Ph.D., Paul E. Greene, Ph.D., Elan D. Louis, M.D., M.S., Karen Marder, M.D., M.P.H., Pietro Mazzoni, M.D., Ph.D., Serge Przedborski, M.D., Ph.D., Seth Pullman, M.D., Yaakov Stern, Ph.D., David Sulzer, Ph.D., Jean Paul Vonsattel, M.D., Cheryl Waters, M.D., Nancy Wexler, Ph.D., Ai Yamamoto, Ph.D.
Evaluating the Role of Mitochondrial Dynamics in Parkinson's Disease in an In Vivo Vertebrate Model: Real-Time Live Imaging of Mitochondrial Dynamics in Dopamine Neurons in Whole Zebrafish Sarah Berman, Ph.D., M.D., and Edward Burton M.D., D.Phil., F.R.C.P., University of Pittsburgh Impact of Low- and High-Frequency Electrical Stimulation on the Inputs, Integrative Properties and Output of the Subthalamic Nucleus Mark Bevan B.Sc., Ph.D., Northwestern University, Chicago
Rush University Medical Center Telomere Biology in Patients with Incident Parkinson’s Disease* Tobias Kurth, M.D., Sc.D., and Robert Y. L. Zee, Ph.D., M.P.H., Brigham and Women’s Hospital, Boston
Brandon R. Barton, M.D., Bryan A. Bernard, Ph.D., Cynthia L. Comella, M.D., Jennifer G. Goldman, M.D., M.S., Christopher G. Goetz, M.D., Deborah A. Hall, M.D., Katie Kompoliti, M.D., Jeffrey Kordower, Ph.D., Kathleen M. Shannon, M.D., Glenn T. Stebbins, Ph.D., Leo Verhagen, M.D., Ph.D.
Identification of Neuroprotective Factors in Tobacco* Leo J. Pallanck, Ph.D., University of Washington
Weill Cornell Medical Center M. Flint Beal, M.D., Claire Henchcliffe, M.D., D.Phil., Melissa J. Nirenberg, M.D., Ph.D.
Small Aromatic Molecules as Novel Inhibitors of Alpha-Synuclein Aggregation Daniel Segal, Ph.D., Tel Aviv University, Israel
Additional Research Programs | $189,000 Fund innovative collaborative programs, such as the Advancing Parkinson’s Treatments grant to the Parkinson Study Group to facilitate the movement of treatments from “bench to bedside.”
Identification of Genes for Parkinson's Disease in an Isolated Greek Community and a Greek Population Cohort Georgia Xiromerisiou Ph.D., M.D., and Henry Houlden M.D., M.R.C.P., Ph.D., University of Thessaly, Greece and University College London, England
*Denotes second year of funding
32 | Our Researchers
Our Researchers Fellowship and Career Development Grants | $1.22 Million Prepare leaders in Parkinson’s research and clinical practice. Research Fellowship Projects | $190,000 Development of a Progressive Neurodegenerative Mouse Model of Parkinson's Disease Ane Korff, Ph.D., St Jude Children's Research Hospital Evaluating Pedunculopontine Nucleus Stimulation as a Treatment for L-DOPA-Resistant Gait Disorders in Advanced Parkinson's Disease Abirami Muralidharan, Ph.D., University of Minnesota The Role of Parkin in Regulating Mitochondrial Dynamics and Homeostasis in Cortical and Dopaminergic Neurons Victor Van Laar, Ph.D., University of Pittsburgh The Locus Coeruleus as a Substrate for Parkinsonian Cognitive Inflexibility Elena Vazey, Ph.D., Medical University of South Carolina
Post Residency Fellowship Training | $720,000 Columbia University Medical Center Rush University Medical Center David Arkadir, M.D., Ph.D. Sheila Rane, M.D. Christopher W. Hess, M.D. Houman Homayoun, M.D. Sheng-Han Kuo, M.D., Ph.D. Alexander Shtilbans, M.D. Sirinan Tazen, M.D. Mary Ann Thenganatt, M.D. Tuhin Virmani, M.D., Ph.D.
Effectiveness of O4 in the Regulation of Toxicity Levels in Parkinson's Disease Models Anna Norton; mentors Erich Wanker, Ph.D., and Jan Bieschke, Ph.D., Charité Medical School of Humboldt University, Germany Role of Beta-Band Activity within the Internal Segment of the Globus Pallidus in Non-Human Primates During a Command/ Countermand Motor Task Shaun Patel; mentor Emad Eskandar, M.D., Massachusetts General Hospital In Vivo and In Vitro Assessment of Urate Modulation by Pyrazinamide Matthew Pearce; mentor Michael A. Schwarzschild, M.D., Ph.D., Massachusetts General Hospital GABAa Receptor Expression Profile and Function in the Globus Pallidus Ruth Quintana; mentor C. Savio Chan, Ph.D., Northwestern University, Chicago Effect of Forced Exercise on Resting State Functional Connectivity in Parkinson’s Disease Chintan Shah; mentor Michael D. Phillips, M.D., Cleveland Clinic Foundation
Summer Student Fellowship Projects | $45,000
Examination of PGC-1 and SIRT3 Pathways in LRRK2 and Alpha-Synuclein Models of Parkinson’s Disease Aarthi Subramanian; mentor M. Flint Beal, M.D., Weill Cornell Medical College
Identifying the Natural and Functional Progression of PD Rachel Boehm; mentor Quincy Almeida B.Sc., M.Sc., Ph.D., Wilfrid Laurier University, Canada
Potential Abnormalities of Brain Circuits of Parkinson’s Disease Lirong Tan; mentor Jing-Huei Lee, Ph.D., University of Cincinnati
R2* Changes in Substantia Nigra and Dentate Nucleus Related to Tremor-and Akinetic/Rigid-Predominant Parkinson’s Disease Christopher DiMaio; mentor Mechelle Lewis, Ph.D., Penn State College of Medicine
The Effect of Wii Fitness Training on Postural Imbalance in Patients with Parkinson’s Disease Megan Trager; mentor Helen Bronte Stewart, M.D., Stanford University
The Effects of Autophagy Enhancement on Alpha-Synuclein In Vivo Darius Ebrahimi-Fakhari; mentor Pamela J. McLean, Ph.D., Massachusetts General Hospital/Harvard Medical School
Collaborative Fellowships | $265,000
Instability in Persons with Parkinsonism: Assessment and Interventions in a Community Setting David Galaso; mentor Lee Dibble, P.T., Ph.D., A.T.C., University of Utah β oscillations in the STN and SNr of Parkinson’s Disease Patients Vahagn Karapetyan; mentor William D. Hutchison, Ph.D., University of Toronto Cardiovascular Autonomic Dysfunction as an Early Biomarker for Parkinson’s Disease Sung Kim; mentor Sheila Fleming, Ph.D., University of Cincinnati College of Medicine Cognitive Profiles of PD: Implications for Dementia Ivy Miller; mentor Alice Cronin-Golomb, Ph.D., Boston University
PDF-AANF Clinician-Scientist Development Award | $165,000 (three years) (co-sponsored with American Academy of Neurology Foundation) Mechanisms of Cell Type-Specific Vulnerability in Synucleinopathy: A Yeast-Stem Cell Dual Discovery Platform Vikram Khurana, M.D., Ph.D., Massachusetts General Hospital PDF-PSG Mentored Clinical Research Award | $100,000 (Funded by a grant from PDF to the Parkinson Study Group) Behavioral Treatment of Anxiety in Parkinson’s (BEHTA-PD): A Pilot Study Jessica Calleo, Ph.D.; mentors Laura Marsh, M.D., and Melinda Stanley, Ph.D., Baylor College of Medicine Genetic and Transcriptional Analysis of Susceptibility for PD Neuropathology Joshua Shulman, M.D., Ph.D.; mentors Philip De Jager, M.D., Ph.D., Lewis Sudarsky, M.D. and Clemens Scherzer, M.D., Harvard/Brigham and Women’s Hospital
The PDF Effect: Annual Report 2011 | 33
Statement of Financial Position
June 30 2011
2010
$779,578
$670,883
550,651
1,055,553
74,161
81,764
12,446,070
11,045,254
235,521
327,069
56,540
56,540
-
236,935
210,723
201,024
$14,353,244
$13,675,022
Accounts payable and accrued expenses
$766,321
$823,380
Grants payable
1,327,440
1,368,427
210,723
201,024
2,304,483
2,392,831
Unrestricted
8,608,353
9,547,208
Temporarily restricted
1,073,946
1,734,983
Permanently restricted
2,366,462
Assets Cash and cash equivalents Contributions and other receivables Other current assets Investments, at fair value Fixed assets, net Other noncurrent assets Life Estate Gift Investments — restricted as to use Total assets
Liabilities and net assets
Deferred compensation plan Total liabilities Net assets
Total net assets Total liabilities and net assets
12,048,761
11,282,191
$14,353,244
$13,675,022
In 2011, PDF was awarded both a four-star rating from Charity Navigator (the highest) and the Charity Seal of Approval from the Wise Giving Alliance of the Better Business Bureau (BBB). 34 | Financial Reports
Financial Reports
Statement of Activities
Year ended June 30, 2010
Year ended June 30, 2011 Unrestricted
Temporarily Permanently Restricted Restricted
Total
Unrestricted
Temporarily Restricted
Total
Operating support and revenue: Contributions
$ 4,022,882
$172,277
-
$4,195,159
$ 4,141,567
$610,493
$4,752,060
2,398,320
-
$2,366,462
4,764,782
3,761,136
-
3,761,136
Special events revenue, net
348,050
-
-
348,050
207,828
-
207,828
Investment income
976,398
-
-
976,398
805,386
-
805,386
Net assets released from restrictions
833,314
(833,314)
-
-
273,709
(273,709)
-
8,578,964
(661,037)
2,366,462
10,284,389
9,189,626
336,784
9,526,410
Research
5,671,135
-
-
5,671,135
5,626,735
-
5,626,735
Public information/patient information and referral services
1,990,591
-
-
1,990,591
2,071,164
-
2,071,164
7,661,726
7,697,899
586,536
574,680
-
Bequests
Total operating support and revenue
Operating expenses: Program services:
Total program services
7,661,726
7,697,899
Supporting services: Management and general
586,536
-
-
574,680
1,269,557
-
-
1,269,557
1,227,820
-
1,227,820
Total supporting services
1,856,093
-
-
1,856,093
1,802,500
-
1,802,500
Total operating expenses
9,517,819
-
-
9,517,819
9,500,399
-
9,500,399
2,366,462
Fundraising
Change in net assets
(938,855)
(661,037)
Net assets, beginning of year
9,547,208
1,734,983
$8,608,353
$1,073,946
Net assets, end of year
$2,366,462
766,570
(310,773)
336,784
26,011
11,282,191
9,857,981
1,398,199
11,256,180
$12,048,761
$9,547,208
$1,734,983
$11,282,191
Administration & Fundraising
20%
Percentage of our dollars spent on our programs and our mission
Advocacy
5%
Education
15%
HOW Our Funds Were Spent 2011 Research
80%
60%
The PDF Effect: Annual Report 2011 | 35
Our People
Board of Directors
Scientific Advisory Board
Officers
Constance Woodruff Atwell, Ph.D. M. Flint Beal, M.D. Robert Burke, M.D. Cynthia L. Comella, M.D., F.A.A.N. David Eidelberg, M.D. Stanley Fahn, M.D., Chair Christopher Goetz, M.D. Lloyd Greene, Ph.D. J. Timothy Greenamyre, M.D., Ph.D. Danna Jennings, M.D. Katie Kompoliti, M.D. Jeffrey H. Kordower, Ph.D. J. William Langston, M.D. Karen Marder, M.D., M.P.H. Serge Przedborski, M.D., Ph.D. Kathleen Shannon, M.D. Yaakov Stern, M.D. David Sulzer, Ph.D. G. Frederick Wooten, M.D. Anne B. Young, M.D., Ph.D.
Page Morton Black Chairman Lewis P. Rowland, M.D. President Timothy A. Pedley, M.D. Vice President Stephen Ackerman Treasurer Isobel Robins Konecky Secretary Stanley Fahn, M.D. Scientific Director
Directors Constance Woodruff Atwell, Ph.D. Karen Elizabeth Burke, M.D., Ph.D. Margo Catsimatidis Barbara Costikyan Peter Dorn George Pennington Egbert III David J. Eger, Ph.D. Stephen B. Flood, Esq. Sarah Belk Gambrell Stephanie Goldman-Pittel Arlene Levine Marshall Loeb Howard DeWitt Morgan Marie D. Schwartz Domna Stanton, Ph.D. Sandra Feagan Stern, Ed.D. Melvin S. Taub Martin Tuchman
Executive Director Robin Anthony Elliott
People with Parkinson's Advisory Council Maria De Leon, M.D. Steve DeWitte Hao Dong, Ph.D. David J. Eger, Ph.D.*, Co-Chair Eric Hellinger Rhona B. Johnson* Daniel J.B. Kiefer, J.D.* Linda M. Morgan, M.B.A., R.Ph. Michael O’Leary* Tom Palizzi Marc Sherman, J.D. Ann Wasson*, Co-Chair Peggy Willocks Fred Woodlief, D.D.S. * founding members
36 | Our People
Image Credits: Page 2 Ben Hide Photography (top); Page 4 Janet Charles (top); Page 4 Modified from Ebrahimi-Fakhari et al., The Journal of Neuroscience; Page 5 Courtesy of Lorenz Studer, M.D.; Page 6 Modified from Vilariño-Güell at al., American Journal of Human Genetics; Page 7 Modified from Shannon et al., Movement Disorders; Page 10 Janet Charles; Page 13 Lars Howlett, The Half Moon Bay Review (top); Page 16 Janet Charles (top); Page 17 Patrick McMullan (B); Patrick McMullan (C); Janet Charles (G); Patrick McMullan (K); Cynthia Servais (N)
1359 Broadway, Suite 1509 | New York, NY 10018 P: (212) 923-4700 F: (212) 923-4778
© 2012 Parkinson’s Disease Foundation
(800) 457-6676 | www.pdf.org | info@pdf.org