Pharmaceutical & Cosmetic Review Africa Q3 2019

AFRICA

Quarter 3 2019 | Volume 4 | Number 3

PHARMACEUTICAL & COSMETIC REVIEW AFRICA

www.pharmacos.co.za

Africa’s skin care

market blooms with opportunity

New laboratory solutions for pharma R&D

Fragrance makes the difference in consumer products

Packaging machinery to change your game

Quarter 3 2019 | Volume 4 | Number 3

AFRICA

www.pharmacos.co.za PHARMACEUTICAL & COSMETIC REVIEW AFRICA

CONTENTS 6 NEWS

Brenntag acquires Chemgrit Cosmetics

New Symrise lab for cosmetics ingredients

Health ministers endorse aggressive plan for vector control

16 Natural wax ingredients offer a great way to innovate

10 EVENTS

Sustainable Palm Oil Conference highlights

Inaugural HPCI South Africa a great success

14 SKIN CARE

Cleansing and moisturisation made easy

Natural wax derived ingredients

Effective sebum control active for African skin

19 FRAGRANCES

PwC report findings on the industry’s value

Symrise creates lab-based jobs in Nigeria

Excite the senses with IFF-LMR naturals

26 Energy saving microbiological safety cabinets

22 PHARMA FOCUS:

LAB EQUIPMENT & SERVICES

Affordable and reliable solutions from Labotec

Abbott opens its second office in sub-Saharan Africa

Energy saving microbiological safety cabinets

27 INDUSTRY TALK

Increased focus on collaboration with China

28 PACKAGING MACHINERY

Automation in action at Bionorica

Tips to implement AI in manufacturing

30

22

Essentials for a successful laboratory How to implement AI in manufacturing P C Africa | QUARTER 3 2019 |

3

PHARMACEUTICAL & COSMETIC REVIEW AFRICA

FROM THE EDITOR

Naturalist consumers drive new beauty innovations

C

onsumer spending on cosmetics

the global producer of fragrances and

and personal care products is

flavours recently expanded its presence in

increasing in Africa. In the skin

the region with new application labs and

care category, the natural beauty

will be creating several jobs there too. This

trend is taking shape as African consumers

exciting regional development and other

make changes to their lifestyle. Take a look

enticing stories about how fragrance makes

at Nigeria – in the past two years there’s

the difference in consumer products are

been an upsurge in product launches with

featured on page 20.

natural and organic claims.

Arami is a natural skin care brand

Because all new product development begins in a lab, our bumper pharma focus

THE TEAM EDITORIAL

Editor: Abby Vorster +27 (0)11 877 6038 abby.vorster@newmedia.co.za Layout & Design: Naresh Budraj Contributors: Jacques Strydom, Marco Mandrioli ADVERTISING Sales Executive: Carla Melless +27 (0)83 260 6060 carla.melless@newmedia.co.za Sales Executive: Anita Raath +27 (0)82 976 6541 anita.raath@newmedia.co.za Sales Executive: Candida Giambo-Kruger +27 (0)71 438 1918 candida.giambo-kruger@newmedia.co.za INTERNATIONAL SALES Germany/Austria/Switzerland: Eisenacher Medien Erhardt Eisenacher +49 228 249 9860 info@eisenacher-medien.de Italy: Ngcombroker Giacomo Rotunno +39 370 101 4694 g.rotunno@ngcombroker.com Taiwan: Ringier Trade Media Sydney Lai +886 4 2329 7318 sydneylai@ringier.com.hk CIRCULATION

handcrafted in small batches in Nigeria. Its

on page 22 is dedicated to supporting

products, which include skin and hair care

readers on their innovation journeys.

oils, body butters, masks and scrubs, claim

You can find out more about Labotec’s

to be formulated with natural ingredients

essential solutions for African laboratories,

PUBLISHING TEAM

sourced on the African continent. YouSkin

Abbott’s recent investment in West

General Manager: Dev Naidoo

beauty is another relatively new beauty

Africa and Telstar’s new energy saving

brand said to be revolutionising the Nigerian

microbiological safety cabinets.

Publishing Manager: Natalie Da Silva +27 (0)11 877 6281 natalie.dasilva@newmedia.co.za

beauty market. Created by Youtopia beauty,

The P&C Africa team would love to

YouSkin is dedicated to restoring skin.

hear from our readers. If you have a great

One of its organic offerings, the YouSkin

manufacturing story or other interesting

vitamin c organic anti-ageing facial serum

news pertaining to the pharma or cosmetics

with hyaluronic acid, promises to address

industries, please send an e-mail to

wrinkles, acne and pigmentation.

abby.vorster@newmedia.co.za to share

It’s forward thinking brands such as these

your story with us.

that inspire ingredients suppliers to innovate.

On page 14, you can read about cold process, one pot raw materials for wash-off

Enjoy the read!

Circulation Manager: Felicity Garbers +27 (0)21 701 1566 felicity.garbers@newmedia.co.za

Production Controller: Mandy Ackerman Art Director: David Kyslinger JOHANNESBURG OFFICE New Media Publishing, Ground floor, Media Park, 69 Kingsway Avenue, Auckland Park, 2092 Tel: +27 (0)11 877 6111, Fax: +27 (0)11 877 6198 POSTAL ADDRESS PO Box 784698, Sandton, Johannesburg, 2146 Published by New Media, a division of Media24 (Pty) Ltd.

and leave-on formulations; natural and

MANAGEMENT TEAM

synthetic functional ingredients made from

MANAGING DIRECTOR: Aileen Lamb

waxy substances; and a new seed extract

COMMERCIAL DIRECTOR: Maria Tiganis

that’s been tested on African skin and

BRAND STRATEGY DIRECTOR: Andrew Nunneley

proven effective in sebum control.

The Nigerian market is highlighted again

CHIEF FINANCIAL OFFICER: Venette Malone

in our section dedicated to fragrances.

HEAD OF HR: Camillah West

Africa’s most populous country has been

CEO: MEDIA24: Ishmet Davidson

high on Symrise’s radar for some time;

HEAD OFFICE

ADVERTISERS’ INDEX

New Media House, 19 Bree Street, Cape Town 8001 PO Box 440, Green Point, Cape Town 8051 Tel: +27 (0)21 417 1111, Fax: +27 (0)21 417 1112 www.newmedia.co.za

Botanichem......................................................7..........................www.botanichem.co.za ChemSystems ..................................................15........................www.chemsystems.co.za Croda SA ..........................................................5..........................www.sederma.com IMCD SA ............................................................13........................www.imcdgroup.com ISW Shrink..........................................................IBC......................www.iswshrink.co.za Nautica Organic Trading ...............................18........................www.nauticaorganics.com O6 Agencies SA................................................21........................www.o6southafrica.com Omron Electronics ...........................................30.......................www.industrial.omron.co.za

Pharmaceutical Cosmetic Review Africa is published by New Media four times a year and circulates to manufacturers, packers and distributors of pharmaceuticals, health products, cosmetics, detergents, soaps, toiletries and allied products. The journal is an up-to-date source of reference for company directors, factory and production managers, marketing executives, engineers, import agents, buyers and research personnel.

Sensetek ...........................................................19........................www.sensetek.biz

While precautions have been taken to ensure the accuracy of its contents and information given to readers, neither the editor, publisher, or its agents can accept responsibility for damages or injury which may arise therefrom. All rights reserved. © Pharmaceutical Cosmetic Review Africa. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, photocopying, electronic, mechanical or otherwise without the prior written permission of the copyright owners.

Wika Instruments..............................................IFC......................www.wika.co.za

Pharmaceutical

Sappi Southern Africa .....................................OBC....................www.sappi.com Savannah Fine Chemicals..............................17........................www.savannah.co.za

Cosmetic Review Africa is printed by Tandym.

Copyright: all rights reserved.

4

| QUARTER 3 2019 | P C Africa

Re-balance the microbiota Ecodermine™ Prebiotic complex dedicated to the skin wellness ess & harmony Hairspa™ Microbiota balance for a healthy scalp Kombuchka PH™ Skin glow enhancer inspired from a probioticc drink

Immediate effect

Long-lasting effect

Before

Kombuchka PH™ is obtained from KOMBUCHA, a tea fermented by a symbiosis of a yeast and a bacterium, that has been consumed for thousands of years.

New tests with Ecodermine™/Hairspa™: these selective and adaptative prebiotics regulate the commensal and pathogenic population of skin microbiota.

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T2.5h

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Smart Science to Improve LivesTM

These naturally derived active ingredients promote a holistic beauty synonymous with harmony, health and well-being.

Follow us on Scan the code for free* sample Part of Croda international Plc.

*Samples will be sent at Sederma’s discretion

Multi-area approach: dry area (arms, legs, face), moist area (intimate area) and oily area (scalp).

After applying E/H 2 %

NEWS

RETAINS ITS NUMBER ONE RAKING FOR THE SEVENTH YEAR in a row, Amway has

USD8.8 billion. As the company looks beyond 2019, its

own has never been more relevant than right now,’

been named the world’s leading direct selling company

strategic investments will focus on driving future growth

says CEO, Milind Pant, in the company’s 2018 sales

on the Direct Selling News Global 100 list. The list ranks

through social commerce, product personalisation

announcement. ‘People around the world like the idea

the top revenue generating direct selling companies

and innovation, as well as new digital experiences for

of entrepreneurship and Amway will continue to fuel the

in the world. Celebrating its 60th anniversary this year,

Amway business owners and their customers. ‘Amway’s

humanity and passion they and Amway business owners

Amway saw a two percent increase of its 2017sales of

cause of helping people build businesses of their

bring to their businesses each day.’ •

BRENNTAG ACQUIRES CHEMGRIT COSMETICS

A NATURAL WAY TO EASE FRIZZ KUPANDA’S BUHLE MANKETTI Seed Oil gives hair a fighting chance against frizz. The seeds are harvested from the manketti tree (also known as the ‘mongongo’ tree), which grows in throughout southern Africa.

The seed oil, which is Cosmos approved and manufactured in accredited EU facilities, is produced from the kernel of manketti

ON 1 AUGUST, Brenntag signed an

Chemgrit Cosmetics operates

fruit. It is available in a cold-press unrefined format or as physically refined.

agreement to acquire the operating

three warehouses, in Johannesburg,

business of Chemgrit Cosmetics,

Durban and Cape Town, and an in-

headquartered in Johannesburg,

house laboratory at its headquarters

linoleic, oleic, palmitic and stearic acids. The combinations and

South Africa. Part of the larger

to provide customers with value

proportions of these acids are not found in other vegetable oils

Chemgrit chemicals group, Chemgrit

added services. These include

traditionally used in cosmetics formulations. It is also rich in vitamin

Cosmetics is an independent

mixing, refilling, redistribution and

E, which provides excellent oxidative stability.

specialty chemical distributor with

delivery, formulating and testing of

a focus on the personal care and

materials and products and other

proven effective in managing hair but in the long term, they often

cleaning markets.

technical support.

lead to dry, greasy, limp and lifeless hair.

Karsten Beckmann, member of

The oil is rich in unsaturated fatty acids including eleostearic,

Products to control frizz traditionally rely on silicones, which are

Kupanda’s Buhle Manketti Seed Oil presents a natural alternative

Anthony Gerace, Brenntag

the management board of Brenntag

Group’s MD of mergers and

to synthetic ingredients whilst still achieving a similar protective

Group and CEO Brenntag Europe,

acquisitions, adds: ‘Based on a

coating effect to silicone.

Middle East and Africa, comments:

dedicated structure and team,

‘With the acquisition of Chemgrit

Chemgrit Cosmetics has a strong

tresses, both directly after application and after 24 hours under a

Cosmetics, we are expanding the

foothold in personal care – one of

constant humidity of 70 percent. The results showed two percent of

industry segment and scope for

the fastest growing market segments

Buhle Maketti Seed Oil decreased frizz volume by 63 percent after

Brenntag South Africa in specialities.

in South Africa and sub-Saharan

application and, after 14 hours, by 31 percent. With a five percent

The company’s cosmetics focus

Africa. Brenntag can use its existing

concentration, the immediate frizz reduction was 71 percent and 51

perfectly complements our existing

structure in east and west Africa

percent after 24 hours.

national food and pharma business

as well as Maghreb to roll out the

and supports our ambition to achieve

cosmetics business line in the region.’

showed a significant improvement when treated with Buhle Maketti

a strong position and comprehensive

The transaction is expected to be

Seed Oil. Interestingly the tests revealed a greater improvement in

offering in South Africa.’

completed by 1 October. •

hair suppleness was achieved with two percent of the oil compared

Clere’s

fan wins big

No.1

A VISIBLY EMOTIONAL Thandiwe Zuma thanked

Su-Marie Annandale. ‘It’s an absolute

Clere with tears in her eyes, on finding out she’d just won

honour and privilege to be able to change

R100 000 in the Are you Clere’s number one fan winter

people’s lives this way.’

promotion. ‘Thank you so much Clere. I really love the

Studies were conducted to assess its anti-frizz efficacy on hair

In vitro studies to investigate its effect on hair suppleness

to five percent.

Due to its positive effect on frizzy hair volume and suppleness, Buhle Manketti Seed Oil is ideal for Ethnic hair care formulations.

Kupanda is a producer of high value, esoteric, natural products, which originate from various regions in Africa. Kupanda is represented throughout southern Africa by Botanichem. •

Zuma, aged 27, from Umlazi in KwaZulu-Natal, South

for the first time, after experiencing flying for the first time, she had no idea she was in fact the grand prize

lotions and cremes; they’re the reason I have such great

Africa, purchased her favourite Clere product – Lanolin &

winner. That day was one of many firsts for Zuma. When

skin,’ she commented.

Glycerine Lotion – at a Pick n Pay in the region. She never

asked what she plans to do with the money, she said

in her wildest dreams would have thought the purchase

she’s going to save it for now. ‘All I know is, my life has

and entry would lead to her winning R100 000.

changed,’ she exclaimed. ‘There aren’t enough words to

The winter promotion, which ran from early March and ended on 31 July, received a whopping 150 000 entries. ‘This has undoubtedly been one of Clere’s most successful competitions to date,’ said brand manager,

6

| QUARTER 3 2019 | P C Africa

It’s the first competition I have ever entered, and I just can’t believe it,’ she added. Landing in Johannesburg

express how happy I am. I’m overwhelmed. Clere, you’ve made my dreams come true.’ •

NEWS

INTRODUCES NEW MOBILE APP LAUNCHED IN EIGHT African countries,

offers a number of key benefits, allowing customers

DHL Express’ innovative mobile platform allows

to access valuable features on the move.

customers in sub-Saharan Africa to track and

‘Customers can access accurate shipping

It’s not only about new technology, but also a different mindset and culture. ‘Our customers are constantly evolving and changing

coordinate the delivery of their shipments with

quotations, find their closest DHL Service Points for

the way they communicate, work, travel and

greater ease and convenience.

easy collections and deliveries and of course, track

consume, so we need to ensure we provide

Hennie Heymans, CEO of DHL Express

their shipments in real time. Embracing digitalisation

solutions agile enough to adapt to their changing

sub-Saharan Africa, says the DHL Express

is the name of the game when it comes to enhancing

needs.’ With online transactions growing

Mobile app is part of the company’s ongoing

customer experience and we are excited to introduce

exponentially in Africa, Heymans says that there

commitment to drive innovations that enhance

yet another exciting mobile application to our

is a clear demand for integrated mobile solutions

customer experience.

customers across the region.’

that allow customers to transact whenever and

‘The app is an exciting new addition to our

According to a report by GSMA Intelligence,

wherever they are.

service offering in sub-Saharan Africa and has been

mobile phones and services are enabling business

launched in South Africa, Kenya, Ghana, Nigeria,

growth in Africa. The mobile ecosystem has made

DHL is constantly working towards providing

‘As the global leader in express logistics,

Ethiopia, Mauritius, Tanzania and Uganda. It will be

a significant contribution to the economy, with an

cutting-edge solutions that help to connect Africa’s

rolled out in a further 40 countries across the region

economic value contribution of USD110 billion,

consumers and business owners with the global

by the end of 2020.’ The DHL Express Mobile app

equivalent to 7.1 percent of the region’s GDP in 2017.

market,’ he concludes. •

Expanded cosmetics

application lab for Symrise IN HOLZMINDEN, GERMANY, Symrise has

says Dr Heinz-Jürgen Bertram, CEO of Symrise. ‘In a

opened a new laboratory for cosmetics ingredients. The

logical next step, we have now reinforced the division

new facility will enable the development, optimisation

with a modern laboratory for the micro protection

and testing of new formulations, utilising the portfolio

category. We intend to develop our division of cosmetic

of antimicrobial ingredients from the company’s micro

ingredients even further. We are the first company in

protection category. The lab will support customer

our sector that started early investments in this business

specific projects as well as the development of

area, which sets us apart from the competition. We

innovative materials for use in cosmetics applications.

recognise opportunities early and take advantage of

The company has broadened its capabilities to conduct on-site workshops as a means of enhancing

their potential.’

Symrise intends to also use the new laboratory to

customer service. Symrise also intends to expand the

study the interaction of the ingredients in formulations

micro protection category’s capabilities within the

and to identify new characteristics.

cosmetic ingredients division. The category consists

‘In the last few years, we have successfully

of a portfolio of safe and effective preservatives and

expanded and developed our business in the area

multifunctional ingredients, as well as skin protection

of cosmetic ingredients,’ says Eder Ramos, global

products such as deodorants, anti-dandruff and

president cosmetic ingredients. ‘We hope to build

hygiene solutions.

on our success with this modern facility, which will

‘In recent years, the cosmetic ingredients division has grown rapidly thanks to exciting developments,’

directly support our customers in the development of cosmetics.’ •

Symrise’s ribbon cutting ceremony in Holzminden, Germany for the expanded laboratory

P C Africa | QUARTER 3 2019 |

7

NEWS

What’s in a pill?

THE IDENTIFICATION OF medicinal products (IDMP) is a highly regulated area.

ISO has a range of standards and guidance documents for IDMP which support the activities of medicines agencies worldwide. They provide the basis for data collection and exchange of information related to the characteristics of medicinal products.

This enables the global identification of the ingredients of medicinal products, necessary for commercial and regulatory purposes.

ISO/TR 14872, Health informatics — Identification of medicinal products — Core principles for maintenance of identifiers and terms, provides a framework for ongoing maintenance and support of identifiers and terms, which meet the criteria of IDMP standards. It describes a service delivery model and core principles which can be used as evaluation criteria for choosing IDMP terminology service providers. It also helps with the development of more robust service level agreements and governance processes used by IDMP data owners and terminology maintenance providers.

The new technical report will be of use to many organisations in the biopharmaceutical and pharmaceutical industries, including global regulators

‘Collaboration amongst regulators, pharmaceutical companies and other parties

involved in the development, authorisation, marketing and distribution of

in the industry helps to improve patient care through improving the reporting and

medicinal products.

documentation of things like adverse-events and patient records,’ he explains.

Convenor of the ISO working group responsible for the IDMP standards and ISO/

ISO/TR 14872 was developed by working group 6, Pharmacy and medicines

TR 14872, Christian Hay, says the terminology maintenance service delivery model

business, of ISO technical committee ISO/TC 215, Health informatics, the secretariat

proposed in this document will help to provide a framework for greater collaboration

of which is held by ANSI, ISO’s member for the USA. It is available from national ISO

and shared data governance amongst IDMP stakeholders.

members or the ISO Store. •

AFRICAN HEALTH MINISTERS

PUSH TO CONTROL VECTOR BORNE DISEASES targeting mosquitoes as well as snails,

troubling burden of vector borne diseases,

and copepods.

primarily malaria, yellow fever, chikungunya,

Speaking during the 69th session of the

Image courtesy of WHO AFRO

The African region has a high and

black flies, sand flies, Tsetse flies, ticks, fleas

dengue and schistosomiasis. While the risk

WHO Regional Committee for Africa, which

of transmission for Zika virus disease remains

took place in the Republic of Congo’s

high, information on incidence and trends of

Brazzaville, Dr Matshidiso Moeti, WHO

the disease is limited. The 10 WHO member

regional director for Africa said: ‘In the

states with the highest burden of malaria

extraordinary push to improve access to

reported an estimated 3.5 million more

case management services for vector borne

malaria cases in 2017 than the previous

diseases and reduce disease transmission

year. More than 440 million people are at

through protective interventions, we lost sight

risk of yellow fever in the region, despite

of disease surveillance and research.’

the availability of a vaccine and

She recalled that effective vector control along with stronger diagnosis and case

improved surveillance.

In May 2017, the World Health Assembly

WITH COUNTRIES IN Africa experiencing

management reduced the malaria cases

adopted a resolution on the Global Vector

increased cases and deaths due to malaria

and deaths in the WHO African region

Control Response 2017 to 2030 strategy to

and other vector borne diseases, 47 health

between 2000 and 2015.

strengthen vector management through

ministers have endorsed the region’s first

‘Now that we have exhausted our arsenal

increased capacity, improved surveillance,

aggressive plan for vector control across

of interventions and the vectors are gaining

better coordination and integrated actions

the continent. The plan recognises the

an upper hand, we have to do things

across sectors and diseases.

need for a push on all-fronts to eliminate

differently,’ Dr Moeti said.

the disease transmitters.

In the form of the Framework on the

The framework on the implementation of

The framework’s priorities take into

the strategy is Africa’s first regional step since

consideration the alarming challenges

the World Health Assembly adoption to fill the

Implementation of the Global Vector

of insecticide resistance, new mosquito

missing link.

Control Response, the plan is a significant

behaviours, environmental risks (unplanned

recalibration of how to bring vector borne

urbanisation), health system weaknesses,

that vector borne diseases are not only a

diseases under control. It contains 10

weak entomological monitoring and

public health problem,’ Dr Moeti added, ‘but

priorities for reducing the burden and threat

evidence for decision-making and the

also a problem for a parade of sectors which

of vector borne diseases in the World Health

depleted expertise and the dearth of

requires a reinvigorated and integrated

Organization (WHO) African region through

domestic resources to sustain interventions

response, critically adjusted to overcome the

locally adapted and sustainable practices

and collaboration.

changed behaviours and conditions.’ •

8

| QUARTER 3 2019 | P C Africa

‘Equally important, the framework clarifies

DIARY

WHAT'S ON IN

2019

October Beauty Istanbul 2 to 4 October ICC Taksim, Istanbul, Turkey www.beauty-istanbul.com

in-cosmetics North America 23 to 24 October New York City, USA www.northamerica.in-cosmetics.com

November

Sustainable Cosmetics Summit Paris, France 4 to 6 November www.sustainablecosmeticssummit.com

CPhi Worldwide

AFRICA

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9

EVENTS

Making sustainable palm oil the norm in Africa

Close to 200 delegates came together on 20 August at La Palm Royal Beach Hotel in Accra, Ghana for Africa’s third Sustainable Palm Oil Conference. The event was hosted to discuss the urgent need for a long term sustainable development plan for palm oil production in Africa.

Godwin Nogheghase Obaseki, governor of Edo State, Nigeria

A

s the presence of the Roundtable on Sustainable Palm Oil (RSPO)

Delegates who attended Africa’s third Sustainable Palm Oil Conference

forest cover countries like Gabon.

RSPO’s assurance director, Salahudin

Stakeholders who spoke at Africa’s third Sustainable Palm Oil Conference, hosted by the RSPO and Proforest

standard to simplify the entry process into the certification system. RSPO members

increases with certified members

Yaacob, called for a long term sustainable

are expected to vote to adopt the

in over 15 countries across Africa,

development plan in the region. ‘RSPO

proposed RSPO independent smallholder

and with stringent new principles and

can only achieve its vision of transforming

standard during its general assembly in

criteria in place, the conference provided

markets to make sustainable palm oil

November. RSPO will continue to work with

an ideal platform for a constructive debate

the norm through collaboration with

local partners on the ground to ensure

around regional vision and renewed

all stakeholders, from growers and

sustainable palm oil production in Africa

commitment from key producing countries.

governments to fi nancial institutions and

benefits people and the planet.

With high profi le dignitaries, growers, NGOs, fi nancial institutions and consumer

NGOs,’ he stated.

Abraham Baffoe, Africa regional director

The conference covered the regional implementation of the 2018 RSPO principles

goods manufacturers in attendance, it

for Proforest, added: ‘A sustainable oil palm

and criteria; the role of financial institutions

was mutually acknowledged if African

industry in Africa is something we are deeply

in promoting sustainable agriculture;

palm oil producing countries achieve their

committed to; it’s wonderful to have so

how governments can mainstream

ambition to convert from net importers to net

much interest from companies and other

sustainability; and opportunities to change

exporters, palm oil production will

stakeholders. We look forward to seeing

the deforestation narrative in African palm

significantly increase.

these connections deepen as a result of this

oil producing countries. The new decent

conference, as we all work together towards

living wage guidance was also socialised

of Edo State, Nigeria delivered a strong

an industry that contributes to the economic

with members as an important tool to help

message to delegates and the industry: ‘If

development of African countries,

improve livelihoods.•

you are not part of the solution, then you are

whilst preserving the crucially important

part of the problem. Let me congratulate all

biodiversity of the region.’

Godwin Nogheghase Obaseki, governor

of you here today, for demonstrating your interests of all of us in Africa to make

With smallholders estimated to account

sustainable palm oil the norm.’

for approximately 70 percent of palm

A NEW FRONTIER FOR OIL PALM

oil production area in Africa, yet roughly

APPROXIMATELY SIX PERCENT of global palm oil

COMMITTED TO SUSTAINABILITY

only 30 percent of output, supporting

is produced in West Africa, making it a new frontier

It’s vitally important any development is

smallholders to improve their yields was

done sustainably, ensuring a balance

another focal point for delegates.

commitment to a solution. It’s in the

between palm oil production and nature

SUPPORTING SMALLHOLDERS

Robert Fagans, Liberia’s deputy minister

for oil palm production. RSPO’s engagement in Africa is growing with 70 members and counting. It first established a physical presence in the region in July 2017 in Ghana and by September 2018 it had

conservation. This is crucial where

of agriculture, commented: ‘Working

livelihoods are intricately connected to the

with smallholders to improve their yields

palm oil industry and natural resources, and

through sustainable farming methods is

contexts are taken into consideration in developing

where oil palm growing areas overlap areas

critical for palm oil growth in Liberia.’ RSPO

and implementing RSPO’s statutes.

of international conservation such as high

has been developing a new, separate

10

| QUARTER 2 2019 | P C Africa

expanded to Cameroon. The work the Africa team does enables the organisation to ensure regional

Learn how to lead and succeed in the competitive world of beauty

Join us for the P&C REVIEW 2020

Beauty Benchmarks & Innovation TH I NK TANK

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See how your brand stacks up against some of the most sustainable ones, meet beauty vloggers and bloggers and get inspired to create great social media content while you learn about how to adapt to rapid changes in the market.

SOUTH AFRICAN PHARMACEUTICAL & COSMETIC REVIEW Date:

Thursday, 20 February 2020

Time:

08h30 to 16h00

Venue:

Media Park Auditorium, Auckland Park, Johannesburg, South Africa

• Early bird Tickets Released! Book before 30 November and save!

Our presenters will educate and enlighten you on claims, social media and influencer marketing, INCI listing dos and don’ts, financial wellness, bricks versus clicks and the rise of e-commerce, sustainability, global trends, market data and category insights.

• Early bird special: R1 125 per person including VAT • Tickets booked after 30 November: R1 495 per person including VAT • You will receive a full breakdown of the day once you have booked and paid for your ticket as well as a breakdown of all the speakers.

• To register, send an e-mail to Natalie.DaSilva@newmedia.co.za with the names and surnames of your conference delegates.

EVENTS

First edition of HPCI South Africa a great success HPCI South Africa expo took place in Johannesburg, in conjunction with the annual Coschem scientific conference. On 4 and 5 September, visitors headed Gallagher Convention Centre to attend the exhibition devoted exclusively to showcasing ingredients for home and personal care products.

As part of the IFSCC international speaker programme, Tony O’Lenick of Siltech LLC gave a presentation on innovating with minimally disruptive formulations

Anna Mommeja and Vijay Bahadur of Seppic, a CJP Chemicals’ principal The Vantage Speciality Chemicals stand at HPCI South Africa 2019

Prof Beverley Summers of Sefako Makgatho Health Sciences University and Erica de Kock of Unicare Ingredients

H

PCI South Africa featured 25

Vanessa Lahn of Evonik Nutrition & Care in Germany with René Spada of Evonik South Africa

Organised by SOFW Journal and

The SOFW Journal and Vincentz Network teams at Gallagher Convention Centre

Based on the theme of ‘innovating the

exhibitors representing 87

Vincentz Network, the HPCI South Africa

possibility, the conference continues to

international companies. It was

expo has set a target to become a leading

be central to the ongoing development of

attended by more than 500 buyers

event on the African continent for the

the African cosmetics industry and a key

personal care and home care markets.

platform for knowledge sharing.

from the personal care and home care markets, who were equally satisfied with this premiere event.

HPCI SOUTH AFRICA EXPO HAS SET A TARGET TO BECOME A LEADING EVENT ON THE AFRICAN CONTINENT FOR THE PERSONAL CARE AND HOME CARE MARKETS The expo is based on the concept of

Exhibitors included AMA Laboratories, Ayanda African Oils, Brenntag South Africa,

SAFETY ASSESSMENT SEMINAR

Carst & Walker SA, CJP Chemicals, Croda

The DGK IKW Safety Assessor Seminar,

SA, Cosmetic Ingredients co-located

organised with the support of Cosmetic,

with Quantum Colours, Dia-Stron, DST

Toiletries & Fragrance Association of South

Cosmeceutical Platform, Evonik Industries,

Africa (CTFA), took place on the second day

Fourchem, Kaza Natural Oils, Millchem,

of the expo and conference. This seminar

Mireuxus, Orkila South Africa, Protea

focused on relevant issues pertaining to the

Chemicals, Savannah Fine Chemicals,

safety of cosmetics.

Solvay Polymers & Chemicals, Symrise, The

The German Cosmetic, Toiletry,

Care Co., Unicare Ingredients and Vantage

Perfumery and Detergent Association (IKW)

Speciality Chemicals.

and the German Society for Scientific and Applied Cosmetics (DGK) shared their

SCIENTIFIC CONFERENCE

unique training concept during the seminar,

In addition to the show, the Coschem

giving prospective safety assessors and

annual scientific conference offered

interested individuals an opportunity to

an extensive programme of lectures

learn about innovations and gain hands

focusing on the dissemination of scientific

on experience.

information. Local and international

The next HPCI South Africa expo will take

knowledge exchange, business interaction

presenters were invited to present papers

place in Johannesburg, in September 2020,

and networking, providing a platform for

outlining research and development in the

in conjunction with the Coschem annual

suppliers and buyers to come together and

cosmetics industry and new materials that

scientific conference. Visit www.hpci-events.

discuss new products and respective needs.

can be brought to market.

com/south-africa/ for more information. •

12

| QUARTER 3 2019 | P C Africa

SKIN CARE

Cleansing and moisturisation made easy

Cold process, one pot raw materials save time, energy and resources in the production process. They also offer consistency in quality for every batch, due to the precision and stability polymers bring to a formulation. Jacques Strydom of ChemSystems discusses the benefits of polymer technologies in wash-off and leave-on systems.

T

here are various ways to cleanse the skin. Two popular methods are normally combined in a multifunctional exfoliating face

or body wash for ultimate cleansing efficiency. This product type involves a surfactant base (normally Sodium Laureth Sulphate) to remove dirt and sebum, with abrasive particles suspended in the base.

These particles could be synthetic wax spheres (historically plastic) or fine pieces of apricot kernel for example, which range in size and abrasiveness.

The trick with an exfoliating cleanser is to suspend the particles uniformly and with stability for the entirety of a product’s shelf life. Aesthetics are also just as important as stability and these products enjoy the inherent ability to display a visually appealing cleansing format. For this reason, a crystal clear liquid is preferred for the particles to properly stand out and entice potential consumers.

Aculyn Excel rheology modifier, available from ChemSystems, is an efficient and cost-effective way to achieve a crystal clear formulation with the required stability. Its ability to suspend particles over a wide pH range (from three to 11), is phenomenal and it’s capable of producing crystal clear gel washes.

14

| QUARTER 3 2019 | P C Africa

Low pH washes, often called pH neutral,

viscosity when certain emollients or

are becoming more popular. The claim

penetration enhancers are added. It is

‘pH neutral’ refers to the pH of human

broadly compatible with a large range of

skin, which is closer to 5.5. It used to be a

surfactants, ensuring versatility.

challenge to make a crystal clear gel wash with good suspension properties at such

SKIN MOISTURISATION

a low pH, because suspension polymers

Creams with moisturisation benefits are

are typically low in pH and need to be

made by heating a water phase and an

neutralised to swell and build viscosity.

emulsifying wax containing oil phase in

Aculyn Excel also requires neutralisation

two separate vessels.

– yet the difference comes in after it has

Both phases are then combined

been neutralised to pH 8, where citric acid

under high shear. Not only does this

is used reduce the pH to the desired level

require vast amounts of energy, but also

of the application.

a specialised homogeniser to ensure a

With Aculyn Excel rheology modifier

smooth and stable emulsion is produced.

you can also suspend bubbles for a

This process also requires well-trained

refreshing and appealing visual effect.

compounders and rigorous quality

It enables the use of softer preservative

control to make sure there is consistency

packages, because it doesn’t lose

between batches.

SKIN CARE

All of these challenges are eliminated

guideline formulation using Flocare

when using the Flocare range of

ET-76 as the sole emulsifier. The

polymeric emulsifiers, also available from

simplest formulation would

ChemSystems. Flocare ET-76 offers great

entail only Flocare ET-76,

viscosity at low inclusion levels over a

water, a preservative

wide pH Range (from six to 11) and readily

and fragrance, but

includes an emollient. Neutralisation is

various emollients,

not required as the product thickens upon

emotives and

addition at any stage of the process,

actives can be

requiring minimal stirring for a beautiful,

added with ease.

homogenous emulsion. Because of the low dosage needed to effectively build

SKIN CREAMS

viscosity and give emolliency in a cold

Some prefer

process, a cost saving can be achieved

using emulsifying

with Flocare ET-76.

waxes for creams,

This polymeric emulsifier is also

because they create

extremely versatile, allowing applications

pure white, opaque

from spray to cream and everything

emulsions that look

in between. It thickens, stabilises and

silky and feel velvety. Yet

texturises without the need for heat or

these formulations normally

neutralisation. Additional emulsifiers are

contain numerous ingredients,

not needed for stability, as the polymer

including primary emulsifiers, secondary

can emulsify up to 30 percent oil. Table

or co-emulsifiers, viscosity builders and

1 shows a typical moisturising cream

emollients etc.

Aculyn Excel rheology modifier is an efficient and cost-effective way to achieve a crystal clear, stable formulation

Akulu Wax LC07-PF from ChemSystems is

TABLE 1: FORMULATION GUIDE

a proprietary wax blend concentrate that

Phase Ingredients INCI

Wt %

ticks all the boxes of the aforementioned

A

Deionised Water Aqua

Qs to

Although heating (85°C) is required in the

100

water phase, Akulu Wax LC07-PF is added

Glycerine Glycerine

2

to the same vessel with medium stirring,

Capric/Caprylic Triglyceride Capric/Caprylic Triglyceride

2

so no homogenisation is needed. A

Finsolv TN C12-C15 Alkyl Benzoate

3

preservative and fragrance can be added

Vit E Acetate Tocopheryl Acetate

0.1

at the end during cooling, resulting in a

Fragrance Parfum

0.6

more basic process to achieve a luxurious

Troycare PE91

Phenoxyethanol, Ethylhexylglycerin

B Flocare ET 76 Sodium Polyacrylate (and) Hydrogenated Polydecene (and) Trideceth-6

1

ingredients in a single raw material.

skin cream with moisturising properties. •

2

ChemSystems – Jacques.Strydom@aeciworld.com

P C Africa | QUARTER 3 2019 |

15

SKIN CARE

Natural wax ingredients

offer a great way to innovate

In Africa, many brands feature natural claims on skin care product packaging. KahlWax, represented throughout southern Africa by Savannah Fine Chemicals, offers several natural and synthetic functional ingredients made from waxy substances. These ingredients are ideal for clean beauty and natural skin care formulations.

K

ahlJellies are unique blends of

• 7036Plus VegoJelly – a fully vegan, plant

rated the emulsions in five categories

waxes and oils with multifunctional

derived blend, mainly made of berry wax

scoring from one (poor) to five (excellent).

benefits. Initially designed as a

and castor oil with a melting point of 42

They could not detect a significant

natural petrolatum alternative,

to 48°C

difference between the two formulations,

they have proven their value as functional ingredients. They have a super soft, silky skin feel and improve the pay-off of colour

• 7037 BerryJelly is the same as VegoJelly but without ascorbyl palmitate • 7235 NaturalJelly is a unique blend of

yet OrganicJelly showed a positive impact on smoothness, non-greasy skin feel, absorption and spreadability.

cosmetics. They can be used in various

mostly beeswax, carnauba wax and

beauty care applications with typical use

castor oil with a slightly higher melting

BERRY WAX

levels ranging from five to 10 percent. They

point ranging from 55 to 62°C

Derived from berry fruit peels of the Rhus

are also very useful in solving blooming or syneresis (oil bleeding) problems.

• 7236 OrganicJelly is the same as 7235 yet it’s made of organic quality ingredients.

These opaque, soft and low melting blends of natural waxes and oils are

verniciflua tree, native to China and the Indian subcontinent, berry wax (INCI: Rhus Verniciflua Peel Cera/Rhus Succedanea

In a paired sensory analysis, an O/W

Fruit Cera) is a pale wax.

homogenous and temperature and light

emulsion formulated with five percent of

The wax partially melts on contact with

stable. KahlJellies are easy to emulsify and

7236 OrganicJelly was compared to the

the skin, improving the feel of emulsions and

show very good compatibility with polar

same formula containing five percent of

supporting a luxury, creamy and nurturing

emollients. The range includes:

petrolatum. There were 15 volunteers who

feel. Berry wax also works as a re-fatting

TABLE 1: REPAIRING HAND OIL PHASE INGREDIENT INCI

%

A Coconut Oil Cocos Nucifera Oil 14.20 WITARIX MCT 60/40 Caprylic/Capric Triglyceride Ad 100 coconut based

6723 Shorea Robusta Resin + Shorea Robusta Resin, Octyldodecanol 12.30 Octyldodecanol

6427 Megasoft Complex Crambe Abyssinica Seed Oil, Euphorbia Cerifera 3.00 Cera, Hydroxystearic Acid, Beta-Sitosterol, Rhus Verniciflua Peel Cera/Rhus Succedanea Fruit Cera, Tocopherol, Helianthus Annuus Seed Oil B Aerosil 200 Silica 4.00 C White Castor Oil Disp COD 8008 Ricinus Communis Seed Oil, CI 77891 0.50 D Passioline Passiflora Edulis Seed Oil 4.20

Arnica Oil Glycine Soja Oil, Arnica Montana Flower Extract, 2.80 Tocopherol Monoi NaTrue Parfum Deeply repair damaged and stressed hands with this natural and vegan skin oil, made with soothing and healing plant oils, and moisturising 6427 Megasoft Complex

16

| QUARTER 3 2019 | P C Africa

0.50

SKIN CARE

agent and supplies the skin with valuable,

a melting range from 48 to 54°C and is

extracted from the trunk of pine trees. The

nutritive components.

very temperature stable. Thanks to its low

blend mainly consists of 70 to 80 percent

peroxide value, 6290 cannot go rancid

beta sitosterol, which has many skin care

and does not require the addition of

benefits, including moisturising and

of triglycerol ester of

antioxidants. It also makes cream whiter,

skin soothing.

C16/C18 Fatty Acid.

the droplet size smaller and it has a positive

Although its melting

influence on emulsion stability.

6290 Berry Wax is a very soft, cream white coloured wax with a high content

point is at around

The special semi-solid consistency of Megasoft Complex is achieved by the addition of berry and candelilla waxes.

52°C, about 20 percent

BLEND OF SPECIALITY INGREDIENTS

Berry wax also improves the way emulsions

of the wax already

6427 Megasoft Complex is a special blend

feel on the skin and supports a luxury,

melts below 30°C.

of natural waxes, oils and emollients,

creamy and nurturing skin feel. It works as

enriched with phytosterols. The main

a re-fatting agent and supplies the skin

with 30 volunteers was

component of 6427 is the seed oil of

with valuable nutritive components.

carried out in a paired

Crambe abyssinica, a plant native to the

6427 deeply nourishes the skin

comparison of an O/W

Mediterranean region and eastern Africa,

while providing a smooth, soft layer of

emulsion with and without

particularly to the area originally called

protection against dehydration without

two percent of 6290. The

Abyssinia, nowadays known as Ethiopia.

feeling greasy or heavy. This makes it an

A sensory analysis

results showed the addition

Crambe abyssinica seed oil is a

ideal choice for skin care products where

of berry wax leads to better skin

renewable and highly biodegradable

a pleasantly light skin feel is desired, such

absorption, faster spreading and

substitute for synthetic silicone oils. Often

as hand and face creams, a hand oil (see

being compared to jojoba oil and broccoli

Table 1 for the formulation guide), lotions

seed oil, it is very silky in texture, easily

and foundations. •

a more pleasant texture.

6290 Berry Wax is very easy to work with and compatible with all commonly

absorbed and does not leave behind a sticky or greasy feeling.

Adding to its skin nourishing qualities,

used ingredients.

6427 Megasoft Complex is enriched with

The product has

a natural phytosterol mixture, which is

KahlWax – www.kahlwax.com Savannah Fine Chemicals – www.savannah.co.za

®

2019-08-26 Ad_P&C Africa_Q3_KahlWax_Pfade.indd 1

26.08.2019 10:29:01

P C Africa | QUARTER 2 2019 |

17

SKIN CARE

Bix’Activ

– tested and effective on oily African skin While 35 percent of people worldwide struggle with oily skin, topical solutions available on the market are often not suitable for African skin types. In a remarkable development for the African skin care industry, BASF has tested its extract, Bix’Activ on dark skin tones.

A

frican skin tends to produce more sebum, has a different composition of sebum and skin lipids, and shininess can be more pronounced. This is why personal care products need to be customised to

its unique requirements. A clinical study done in Mauritius has confirmed BASF’s Bix’Activ is especially effective on oily African skin. An overproduction of sebum and resulting shininess are a common concern when it comes to African skin. In 2018, an in vivo study was done on an Asian population where Bix’Activ was shown to decrease sebaceous gland activity, pore size and skin imperfection. A new placebo controlled clinical study has also confirmed the efficacy of Bix’Activ on the unique characteristics of African skin. The study showed a decrease in

D0 – before treatment and D28 – after 28 days of product application

sebum excretion to the skin surface by 44 percent and an

volunteers reported an improvement in their skin’s appearance.

11 percent reduction in shininess compared to the first day of

For instance, 93 percent perceived their skin to be less oily, while

the study (D0). In a self-assessment, a significant majority of the

90 percent felt their skin looked healthier.

BIXA ORELLANA SEED EXTRACT Oily skin is due to hyperactive glands that produce excess sebum. Its causes are varied and range from hormonal changes to environmental factors, such as weather or air pollution and lifestyle, including the consumption of alcohol, a diet rich in dairy products and sugar. Bix’Activ is an extract of Bixa Orellana seeds. It addresses the dermatological roots of oily skin conditions by restricting the overproduction of lipids in sebaceous glands. The active ingredient conforms to the Cosmos standard for natural and organic cosmetics and is suitable for use in Natrue certified formulations.

STRONG REGIONAL APPROACH Developing customised personal care products for African type of skin is part of BASF’s overall strategy to develop consumeroriented solutions for the sub-Saharan African beauty market.

In February, BASF opened its new personal care application technology laboratory in Lagos, Nigeria, which provides regional competence for the market. The opening of the application technology laboratory in Nigeria was just the start of BASF’s sub-Saharan African journey. It is working closely with customers to support them in developing innovative personal care solutions for African skin and hair. With its on-site technical support and customised personal care concepts, BASF aims to become a preferred partner to customers in the personal care industry in sub-Saharan Africa. The company’s investment in the region will increase its footprint on the continent and will nurture partnerships and innovation geared towards sustainable growth.• BASF – www.carecreations.basf.com

18

| QUARTER 3 2019 | P C Africa

FRAGRANCES

Fragrance makes the difference

A study conducted by PwC on behalf of IFRA reveals fragrance boosts the value of consumer goods. In perfumes, cosmetics and cleaning products, it can boost their value by 10 times.

E

ntitled The Value of Fragrance, the

The report also shows the social

fragrance, cosmetics and personal care

report shows the manufacturing

value of the industry. It supports 26 000

products, as well as household products

of fragrance ingredients alone

highly skilled jobs and nearly 400 000

and detergents.

contributes €7.2 billion in

jobs at supplier level in more than

economic value. These ingredients are

50 countries. This helps to sustain and

INVESTED IN EMPLOYEES AND R&D

responsible for between €48 billion and

give back to communities around

Martina Bianchini, IFRA president, says:

€72 billion in value added for 25 consumer

the world.

‘This report highlights how the fragrance

product categories.

In 2017, the fragrance industry generated sales worth €7.3 billion,

‘Fragrance has the power to make

industry is sophisticated, global and

the difference – in every sense,’

innovative. As an industry, we invest eight

adds Carlos.

percent of net sales in R&D – higher than

contributing to €357 billion in global

all sectors in the European Union other

sales generated by consumer product

MAPPING THE VALUE CHAIN

than pharmaceuticals and technology

manufacturing and retailing.

One of the innovations of the report

hardware. Per employee, the value

is the mapping of the complex global

added is €135 000 – higher than in the

Fragrance Association (IFRA), Michael

fragrance value chain. This chain begins

automotive sector and which underlines

Carlos, comments: ‘The fragrance

with 3 000 suppliers of natural and

how much talent and creativity we have

industry may be relatively small, but it

synthetic raw materials, from smallholder

in our industry.’

makes a big impression. This report shows

farms to synthetics manufacturers. It

how we add significant economic value to

continues with an innovative fragrance

Middle East and Africa, Asia-Pacific and

our suppliers and customers, as well

industry (represented globally by IFRA),

Latin America, is based on data gathered

as consumers.’

which delivers ingredients for use in fine

and analysed by PwC for the year 2017. •

Chairman of the International

The report, which covers Europe, the

Tel 011 608 4944 Fax 011 608 4948 Email sales@sensetek.biz

Sensetek.indd 1

2017/03/02 11:50 AM

P C Africa | QUARTER 3 2019 |

19

FRAGRANCES

Fruit –

a challenge in perfumery:

A

symbol of pleasure, softness and gourmet delight, fruits

are one of perfumery’s most frequently used raw materials.

Rudy McLean, pictured second from the left, with Symrise executives and special guests, who attend the launch of the new labs in Nigeria

Developing scent,

Despite their volatile side, their olfactory richness makes them an ingredient of choice paired with floral, floriental or chypre notes

care and taste solutions for Nigeria Symrise is setting up application labs in Nigeria for the first time in its corporate history. On 4 September, the global fragrance and flavours manufacturer, with its head office in Germany, opened the new facilities in Lagos, the largest city in the west African country.

in fragrances for women and accompanying fougère or woody notes to appeal to men.

While perfume compositions have long highlighted the appetising and confectionery side of fruits, the search for authenticity is leading perfumers to fashion them in a much more natural way. As a result, sickly sweet and artificial strawberry

R

flavoured candies have given way udy McLean, managing director at

itself with the local markets. Beyond this,

to the fresh and sparkling, juicy

Symrise South Africa, says the new

the team has built close and lasting

pulp and flesh.

application labs will strengthen the

relationships with customers.

company’s presence and underpin

Fruits are aqueous bases

The goal of the new application labs is

from which essential oils cannot

to incorporate customer preferences and

be obtained. This gap in the

market requirements in regional product

perfumer’s organ can now be

Saharan Africa will work on developing

development and with speed. To achieve

partly filled thanks to Symtrap

applications using Symrise’s fragrances and

this, Symrise will employ three new lab

technology, which is unique to

cosmetics ingredients. Flavours for various

specialists in Nigeria.

Symrise and implemented in

our growth goals in the region.

In the labs, Symrise experts from sub-

application areas, in particular

Amazonia. It makes it possible

With more than 190 million

for beverages, sweet applications and

inhabitants, Nigeria is by far the most

to capture the essence of the

savoury foods, will also be developed.

populous African nation and a key

finest natural ingredients of the

regional economy.

Amazon region, where wild nature

The company wants to meet the preferences of regional customers as closely as possible with this

we are enhancing our

local expansion.

footprint in the region

‘With these application labs, we can

and intensifying

create products in the market for the

our long-term

market,’ McLean adds. ‘We can deepen our

commitment to

understanding of the preferences

Nigeria and west

and needs of the region’s people and –

Africa,’ McLean

where possible – use raw materials

concludes.•

from the region.’

COMMITTED TO THE REGION The history of Symrise is closely connected

of an exceptional, one of a kind

‘With this new investment,

character still prevails today.

DID YOU KNOW?

Symrise is now able to offer, authentic passion fruit with a

has been active in the African country

20

| QUARTER 3 2019 | P C Africa

found in aqueous

for example, a juicy, fruity and

Flavour & Nutrition segments, the company

Symrise has worked intensively to familiarise

fragrance molecules

it’s all happening on Instagram, solutions such as where the Fine Fragrance entity the rinsing water shares its fragrance stories, offering or residual juice users a chance to find out about from the extraction, Symrise perfumers, their creations, distillation or inspirations and vision of tomorrow’s perfumery. Follow lyophilisation of plants @finefragrancestories_ and fruit. It is thanks bysymrise on Instagram. to this technology that

with Nigeria. With its Scent & Care and

for more than 30 years. During this time,

The process captures

Symrise – www.symrise.com

temptingly delicious effect.•

Balsam of Peru, an aromatic resin obtained from the balsam tree, is used to fragrance perfumes and toiletries

FRAGRANCES

Excite the senses with IFF-LMR naturals IFF-LMR, a subsidiary of International Flavors & Fragrances, has gained FairWild certification for Peru Balsam from El Salvador, an ingredient used in perfumery. The certification recognises IFF’s commitment to sustainable harvesting processes and fair working conditions.

T

he FairWild Foundation promotes

communities. IFF-LMR offers a portfolio of

Madagascar to honour its rich biodiversity

the sustainable use of wild

sustainable fragrance ingredients that

and the tradition of producing perfumery

collected ingredients, with a fair

satisfy our customers’ needs and reduce

ingredients. The subsidiary’s R&D team

deal for those involved throughout

our environmental footprint.’

is deployed to improve aspects of

the supply chain. FairWild Standards

yield and quality, including cultivation,

ensure the continued use and long-term

HONOURING BIODIVERSITY

harvesting, post-harvesting and the

survival of wild species and populations

Africa is home to 25 percent of the world’s

transformation of the crops. Its scientists

in their habitats, while respecting

botanical species. In Madagascar,

partner with the botanical and extraction

traditions and cultures and supporting

located off the coast of East Africa, IFF-

research departments at Madagascar’s

the livelihoods of stakeholders. This Peru

LMR has established a sourcing platform

Antananarivo University to identify

Balsam is said to be the first FairWild

with two goals:

breakthrough perfumery ingredients.

certified fragrance ingredient to be

1. to improve the quality, transparency,

These long-standing relationships allow

commercially available globally.

and sustainability of ingredients

IFF-LMR to share its botanical expertise

sourced in the region while optimising

and provide guidance on achieving

of IFF-LMR comments: ‘Gaining FairWild

the supply chain to obtain full

the requirements of For Life, FairWild

certification for Peru Balsam underscores

traceability

and Eco-Cert certifications for

Bertrand de Preville, general manager

our commitment to sourcing ingredients responsibly, conserving natural resources and improving the livelihoods of farming

2. to develop new botanicals sourced in the region.

IFF-LMR partners with producers in

sustainable practices.•

IFF – www.iff.com

P C Africa | QUARTER 3 2019 |

21

PHARMA FOCUS: LAB EQUIPMENT & SERVICES

Essentials for

a successful laboratory Labotec offers African laboratories quality and reliable equipment at an affordable price. The company’s regional footprint avoids obstacles with time delays, often experienced when sourcing equipment and spares for maintenance from international suppliers.

A

fter extensive trials and testing

The Labotec Eco range sports around

The Labotec EcoBath, featuring a powerful circulation pump

temperature sensor. These popular

in the Labotec workshop in

32 product ranges often used in

benchtop models are based on a new

a quest to find elementary

laboratories. The emphasis is on quality

ergonomic design with stainless steel

products manufactured

South African manufactured durable

body construction and a slam lock door

within the sub-Saharan African region,

products available at an economical

handle for easy closing.

the company has released its own

price for the African market.

branded range of widely used laboratory

The company’s EcoTherm ovens also

The Eco range is an extension of the

sport the new stainless-steel body and

essentials. These products live up to

existing popular Labotec EcoTherm and

slam lock door. They operate in the

quality expectations and provide a good

IncoTherm ovens and incubators. These

temperature range of ambient +7°C

basic starting point.

products have a widespread footprint in

to 250°C with a choice of five different

South African laboratories and proven

capacities and are ideal for drying

competency over three The Labotec EcoStir overhead stirrer

decades.

Designed to provide fundamental cost advantages, with the timeous availability of in-stock spares from the company’s qualified technical maintenance workshop, the Eco

processes, ageing, curing

DID YOU KNOW?

and general thermal investigations.

Range extensions

include the EcoTherm Laboratory supplies such as reagents and slides; diagnostic glassware drying test kits, syringes, needles, gloves, and oven and industrial infection control items; and medical oven with an internal equipment such as microscopes, blood volume up to 1 400ℓ, pressure machines and glucometers are which operates in the among the diverse range of goods in high demand in the African temperature range of healthcare sector. Source: Frost ambient +7°C to 250°C. & Sullivan Africa Healthcare The larger size 2 000ℓ Industry Outlook oven operates between

range offers the necessary specified accuracy and

ambient +7°C and 130°C. The IncoShake range consists of two

uniformity during use. Labotec supplies

150ℓ models with temperature ranges of

this range with a two year guarantee.

0 to 60°C. The difference is one model

The Labotec Eco range complements

has a refrigeration system and automatic

the company’s Precision ranges of

defrost, plus there is a smaller 14ℓ entry

balances and furnaces launched last

level solution for sample agitation at

year. Labotec has also launched a

a controlled temperature. The units all

new filtration range, which includes

feature microprocessor speed control

filter paper, filter manifolds and

and digital speed indication with an easy

membrane filters.

to use setting knob and 120-minute timer with infinity setting.

HEATING AND COOLING

22

| QUARTER 3 2019 | P C Africa

Labotec IncoGrow growth chambers

The Labotec IncoTherm incubators are

provide reproducible light or temperature

ideal for use in microbiology and related

conditions for all growing requirements.

fields. They operate at temperatures

They feature an automatic defrost

ranging from ambient +7°C to 110°C with

function for ease of use, a weekly

a choice of six capacities. IncoTherm’s

programmable timer and independently

digital series has a high accuracy PT100

controlled lighting allowing a selection

PHARMA FOCUS: LAB EQUIPMENT & SERVICES

of different lux levels. The EcoBath

MIXING, STIRRING AND SHAKING

waterbaths and circulators ensure

The Labotec MagneStir range has

consistent and reproducible mixing

uniform and accurate heating and

a magnetic stirrer suitable for all

and stirring results and are suitable for

cooling with a powerful circulation pump

applications. The range includes

most types of lab applications where

for uniform temperature distribution

basic and ceramic models, as well

controlled stirring and heating is required.

in the bath. They are equipped with a

as models with a chemical resistance

high accurate pt100 temperature sensor

heating plate and integrated temperature

maximum volumes of 20ℓ, has solid state

and electronic PID control with a digital

probe with digital display. There is also

electronic control, an adjustable height

indication of set and process value.

a heavy-duty stainless-steel model for

and easy to set digital control.

The EcoBath heatable range is suitable

temperature and shaking water baths.

Suitable for many types of digestion experiments, the EcoSteam bath can accommodate a variety of round bottom kjeldahl flasks and has a unique lid design that ensures all water vapour returns back to the bath.

EcoBlock heating blocks feature PID controllers with various block hole

The EcoStir overhead stirrer can handle

The OrbiShake platform shaker with its

stirring larger volumes.

for water or oil applications, while there are other options for circulating, low

All the models in the range will give

robust, functional design and trouble-

THE LABOTEC ECO RANGE SPORTS AROUND 32 PRODUCT RANGES OFTEN USED IN LABORATORIES

free operation creates a shaking motion for mixing liquids in flasks conducive to culturing cells. A full range of accessories is available for all clamping requirements.

GENERAL LAB SOLUTIONS SonicClean ultrasonic cleaners are effective for a variety of cleaning applications. Manufactured from longlasting stainless-steel tanks, there are four

diameter selections, and a choice of a

sizes all fitted with 60-minute timers with a

maximum temperature from ambient to

bypass function. The bigger models have

200°C or 450°C.

drain taps for easy maintenance.

Engineered for longevity, there are

The Labotec LabTrolley has a 50kg

two EcoPlate hotplate finishes suitable

per shelf carrying capacity and is

for different applications. The mild steel

characterised by its robust stainless-

hotplate is the laboratory workhorse

steel construction and hygienic, easy

for general heating while the more

to clean design. The 100mm easy

advanced digital aluminium EcoPlate

glide, silent running heavy duty caster

is equipped with PID temperature

wheels ensure no snagging on floor

control and ensures even temperature

joints or lift entrances.

distribution for more

FilterPress and RiffleSplitters ranges are

sensitive applications.

Labotec’s EcoBlock heating block

used in the industrial laboratories. The FilterPress is used for de-watering slurry and general investigation of remnants.

The RiffleSplitters are available in a variety of chamber sizes for even splitting of your sample for further analysis.

Labotec was one of the first laboratory supply companies in South Africa, with offices in Johannesburg, Cape Town and Durban. Over the years, its sales footprint has grown beyond South Africa, leading to the establishment of an exports division focused on the African market.•

Labotec – www.labotec.co.za

A Labotec EcoTherm oven

P C Africa | QUARTER 3 2019 |

23

PHARMA FOCUS: LAB EQUIPMENT & SERVICES

Abbott continues to invest in east Africa

In September, Abbott, a leading global healthcare company, announced the opening of its second office in sub-Saharan Africa at The Watermark – Nairobi Garage Business Park.

T

he new office will function as

KENYAN INVESTMENTS

a headquarter for Abbott’s

In Kenya, Abbott’s Diagnostics

operations in east Africa and is

businesses have supplied millions

intended to support its expanded

of rapid tests for HIV, malaria and

growth opportunities in the region.

hepatitis. Abbott core laboratory

Abbott’s other office in sub-Saharan

and molecular systems at

Africa has been based in Johannesburg,

multiple sites analyse high

South Africa, since 1940.

volumes of test samples critical to

‘The economies of Kenya and east Africa are growing rapidly and present a tremendous opportunity for global

the health and wellbeing of all Kenyans.

In 2016, Abbott’s established

Abbott’s Alinity s offers a significant leap forward when it comes to speed, automation and efficiency for blood and plasma screening

and created the first emergency medical

investment and partnership,’ says

pharmaceuticals business invested in a

facilities and residency programme in

Maxwell Okello, CEO, American

manufacturer in the region, acquiring

east Africa.

Chamber of Commerce, Kenya. ‘We are

several products developed for

delighted to see American companies

keeping children healthy. Since 2009,

REACHING RURAL RWANDA

like Abbott increase their commitment

the company’s nutrition business has

In Rwanda, Abbott is collaborating

to working with local governments and

provided trusted and scientifically proven

with the Ministry of Health to establish

the private sector to accelerate the

nutrition solutions to help Kenyans of all

a new model for the decentralisation

economic growth and prosperity of

ages live stronger and healthier lives.

of healthcare to reach people in rural

the region.’

As the population and economies of the east African community continue to grow, its member states are increasingly focused on strengthening their health systems to improve the health outcomes of their people – their most important resource – and the future of Africa.

COMMITTED TO AFRICA Damian Halloran, Abbott’s vice president,

areas. The company also provides

ABBOTT IS DEEPENING ITS LONG-STANDING COMMITMENT TO KENYA AND EAST AFRICA AS A WHOLE

infectious disease-emerging markets,

technical expertise and funds a pilot programme of second-generation health posts, which will deliver a wide range of primary health services for prenatal and paediatric care, testing and treatment of infectious diseases, and wound care.

RAPID DIAGNOSTICS IN UGANDA Abbott’s diagnostics business plays a key role in Uganda’s hepatitis C elimination programme and has a

deepening its long-standing commitment

STRENGTHENED HEALTHCARE IN TANZANIA

to Kenya, and to East Africa as a whole,

Since 2001, Abbott and the Abbott

by increasing our resources in the region.

Fund have worked closely with the

We are working with governments and

government of Tanzania to strengthen

Service, one of the largest HIV testing

stakeholders in the region to realize

the country’s healthcare system. With

laboratories in the world, operates

sustainable healthcare so that people

more than USD$130 million invested to

Abbott’s molecular systems, which tested

in all places and stages of life can

date and the contributions of specialised

more than 900 000 samples last year.

achieve more, and live not just longer,

Abbott experts, this unique public-

Abbott’s rapid diagnostic tests for HIV,

but better lives.’

private partnership is finding sustainable

syphilis and malaria are widely used

solutions to critical healthcare

for screening those diseases; several

and an ongoing commitment to Africa,

challenges – elevating testing, treatment

hundred PIMA analysers do CD4 testing

Abbott is advancing science and

and care for people across the country.

throughout Uganda. •

technology to constantly shape new

As part of this initiative, Abbott has

methods of care and improve treatment

helped upgrade patient testing and care

standards across the continent.

at the country’s largest public hospital

rapid diagnostics, comments: ‘Abbott is

With more than 75 years of heritage

24

| QUARTER 3 2019 | P C Africa

presence in large hospitals, providing results to facilitate prognosis and diagnosis of various diseases.

The National Health Laboratory

Abbott – www.abbott.com

PHARMA FOCUS: LAB EQUIPMENT & SERVICES

European Pharmacopoeia

updates to address new challenges The newly released 10th Edition of the European Pharmacopoeia, contains 2 420 monographs and 374 general texts, including general monographs and methods of analysis, as well as around 2 780 descriptions of reagents.

The 10 th Edition of the European Pharmacopoeia and the subsequent updates will be available in print and electronic formats

DID YOU KNOW?

and innovative treatments, such

The European Pharmacopoeia is a single reference work for the quality control of medicines. The official standards it contains provide a scientific basis for quality control during the entire life cycle of a product.

as infliximab concentrated solution (2928), the revised general monograph on products of recombinant DNA technology and a new chapter on the quantification and characterisation of residual host

cell DNA. All offer quality standards for a wide range of biological medicines while allowing for the necessary flexibility.

I

n total, 114 new monographs have

recent changes in regulatory processes

been introduced, compared to

at European and international level.’

Edition 9.0. Of these, 17 concern active substances of high medical

SPECTROPHOTOMETRY

interest covering key therapeutic

In the 10 th Edition of the European

classes, such as anti-neoplastics,

Pharmacopoeia, thoroughly revised

immunosuppressants, anti-arrhythmics,

general chapters include those on

anti-thrombotics, antiretrovirals or

infrared absorption spectrophotometry

analgesics. Seven monographs

and ultraviolet and visible absorption

concern finished products containing

spectrophotometry. The latter

chemically defined active substances.

now covers UV-Vis detectors for

Altogether 683 revisions were made, taking into account the latest scientific and technical evolutions,

chromatographic systems and process analytical technology applications.

Acceptance criteria for elemental

legal and regulatory developments,

impurity levels, as defined in the ICH

the increasing demand for generic

Q3D guideline, are reflected in this new

and biosimilar products, new risks in

edition. It also provides standardised

the public health domain and the

approaches for correctly determining

globalisation of trade and commerce.

elemental impurity levels. Further

Dr Susanne Keitel, director of the

work on elemental impurities include

European Directorate for the Quality

the revision of the general monographs

of Medicines and Healthcare (EDQM),

on substances for pharmaceutical use

explains: ‘This updated edition

and pharmaceutical preparations,

responds to the latest developments

the general chapters on elemental

in the pharma industry and defines

Impurities and their determination,

quality and safety standards for

as well as numerous individual

medicines on the basis of scientific

monographs.

ANIMAL TESTING The 3Rs concept – of replacement, reduction and refinement – which is aimed at protecting animals used for scientific purposes, is widely reflected in the 10 th Edition. The test for abnormal toxicity was completely removed, and altogether, 49 individual monographs, 36 of which concern vaccines for human use, were revised.

Another step is the new chapter on the substitution of in vivo methods by in vitro methods for the quality control of vaccines, which will ease the transition from in vivo to in vitro methods. In total, 59 monographs were revised in this context.

SUBSEQUENT UPDATES The 10 th Edition of the European Pharmacopoeia will become effective on 1 January 2020 and will be updated with eight supplements (10.0 to 10.8) over the following three years. Functionalities of the electronic versions have been improved to better address users’ needs. These improvements allow for more effective user management, including re-allocation of access rights amongst user groups. •

expertise. It includes a whole variety of new substances and products,

BIOLOGICAL MEDICINES

while reflecting the latest scientific and

In the field of biologicals, several

technological advances, as well as

new monographs address existing

Visit https://bit.ly/2lUTkYG for more information on the 10th Edition.

P C Africa | QUARTER 3 2019 |

25

PHARMA FOCUS: LAB EQUIPMENT & SERVICES

Energy saving

microbiological safety cabinets Telstar has consolidated its position as a leader in laboratory applications in the pharmaceutical, cosmetics and biotechnology industries. Backed by 50 years’ experience and a strong international presence, the company offers a range of compact and ergonomic solutions for life sciences applications.

I

ntended for the laminar flow

and dimmable LED illumination, which

system. The innovative design of this freeze

manipulation of microorganisms

ensures optimum protection levels as well

dryer results in an extremely compact unit

with biological risk levels 2 and 3,

as low energy consumption.

with large condensation capacity up to

Telstar’s safety cabinets feature an

Bio II Advance Plus cabinets are

eight litres.

innovative design. They also offer a smaller

designed in compliance with the

footprint than the market average whilst

European standard EN 12469 and certified

an automatic defrosting function for

maintaining a comfortable workspace.

by TÜV-Nord, in Hamburg, Germany.

quick and easy de-icing. Its design enables many product formats to be pre-

The new compact range of microbiological safety cabinets, Bio II Advance Plus, are 759mm in width, 1 260mm in height and provide a working volume of 340dm3.

Equipped to achieve maximum efficiency, the microbiological safety cabinets integrate energy saving EC fans

The LyoQuest’s ice condenser includes

BIO II ADVANCE PLUS CABINETS ARE DESIGNED IN COMPLIANCE WITH THE EUROPEAN STANDARD EN 12469 AND CERTIFIED BY TÜV-NORD

frozen in the unit, without the need for an additional freezer.

COLD STORAGE TECHNOLOGY Boreas from Telstar is a new -86°C ultra-low temperature freezer designed to increase average performance by 20 percent. An innovative mechanical design enhances robustness, efficiency and ergonomics as well as ensuring the integrity of the cold preservation process. Equipped with vacuum panels, the freezer guarantees the highest level of thermal insulation and

COMPACT FREEZE DRYERS

maintains a temperature of -80°C with

The company also offers the latest

ambient temperatures up to +28°C.

generation of compact laboratory freeze

Unlike standard freezers designed with

dryers, integrating pre-freezing primary

panels based on polyurethane foam, a

drying and secondary drying processes.

thinner inner insulation provides Boreas

Telstar LyoQuest is an innovative benchtop

with an enlarged storage capacity of

laboratory freeze dryer that combines

up to 30 percent. It also uses high purity

flexibility with performance in a single unit.

natural refrigerant CFC-free gases,

This ensures users can carry out complete

which contribute to preservation of the

cycles using different containers, such as

environment. The ecological ultra-low

vials, trays, ampoules and flasks, with the

freezers line has been developed using

same piece of equipment.

Telstar’s cold storage technology. •

In addition to being versatile, LyoQuest enables users to create recipes that The Bio II Advance Plus microbiological safety cabinet

26

| QUARTER 3 2019 | P C Africa

include time, temperature and vacuum control via its integrated PLC control

Telstar – www.telstar.com

INDUSTRY TALK

More Chinese pharma firms to invest in African markets African countries and China see significant opportunities in strengthening collaboration in the pharma and healthcare fields. This is according to a new insights report from Fitch Solutions, a credit and macro intelligence solutions firm. systems, which are expected to significantly increase demand for medicines. It’s

60 Figure 1: 2017 data of Chinese healthcare products exported to African countries – larger markets have been targeted first, but more will follow

presently estimated, 47 percent of people in Africa do not have access to quality medicines. Generics manufacturers are expected to benefit the most from this trend

40

as governments will be looking to contain costs in parallel with expanding health services. Chinese drug makers will likely focus initially on lower risk, higher reward

20

African markets. With only 34 of the 55 African countries having a significant level of pharma production, Chinese companies may explore the prospects of establishing

0

South Africa

Egypt

Nigeria

Kenya

Algeria

Ghana

Tanzania

their own manufacturing sites. This will allow them to build trust with local stakeholders, set up more efficient distribution networks

Chinese exports of health products to African countries in 2017 (USDmn)

and procure cheaper medicines faster, while fulfilling commitments of supporting

I

African countries by generating jobs

n an effort to cover healthcare needs

country – Chinese pharma and medical

and decrease their dependency on

equipment investors held discussions

international donations, countries in

with delegates from a number of

Africa are increasingly looking to entice

African countries to discuss investment

and income.

UNFAVOURABLE ASPECTS Despite the significant growth potential

and strengthen collaborations with Chinese

opportunities in the African continent. More

healthcare companies. In turn, these

many African countries, a number of them

specifically, representatives of investment

Chinese firms are looking expand their

will continue to be marred by persistent

promotion agencies from Ethiopia, Kenya,

operations and exports in African markets

issues. Favouring local production is a

Mozambique and Zambia explored

and seize the revenue earning potential

common practice in African countries,

opportunities with Chinese firms in the

these countries hold. This is strengthened by

creating an unfavourable environment

areas of vaccinations, medical equipment

other large-scale projects China is currently

for international drug makers. In cases

and drug production.

where drug makers have manufacturing

undertaking in Africa, such as the Belt & Road project, and the deterrent effect of

STRONG EXPORT POTENTIAL

Western firms’ established presence in

Chinese pharma companies are expected

neighbouring markets.

to increase their exports and physical

Until now, Chinese pharma imports

sites in Africa, political uncertainty, policy discontinuation and civil unrest can pose significant risks to their operations.

The regulatory environment will remain

presence in Africa in the medium term.

accounted for less than five percent of total

underdeveloped by Western standards,

Previously noted by Fitch Solutions, certain

health products imports in Africa (2017

even though it is believed the establishment

African countries present opportunities

data), with Chinese firms primarily focused

of the African Medicines Agency will

for international drug makers, supported

on larger markets such as South Africa,

ameliorate and harmonise regulatory

by a large and growing population, a

Egypt and Nigeria (see Figure 1).

regimes in certain African countries in the

high prevalence of both infectious and

medium term. Chinese drug makers will

chronic diseases, and a surge in average

READY TO INVEST

also have to compete with their Indian

life expectancy. African countries currently

Increased partnership efforts between

counterparts, which have established a

import approximately 70 percent of their

China and Africa are evident in the

longer and stronger presence in the African

pharma products, highlighting the strong

growing interest in exploring investment

generics market. •

export potential they hold for Chinese

opportunities. In June, at the Convention

firms. The attractiveness of African pharma

on Pharmaceuticals China – the biggest

markets is also supported by intensifying

pharma products trade fair in the

efforts to introduce universal healthcare

Fitch Solutions – www.fitchsolutions.com

P C Africa | QUARTER 3 2019 |

27

PACKAGING MACHINERY

Automation in action on a liquids line

Bavarian pharma manufacturer, Bionorica trusts in solutions from Romaco, a leading global supplier of processing and packaging equipment. With the help of Romaco, Bionorica recently automated various steps in its liquids production plant. By Marco Mandrioli, Romaco’s area sales manager

F

or over 85 years, Bionorica has been unlocking the healing power of nature to produce effective and well tolerated herbal medicines. The company has grown from a one-man business to a global player, employing

about 1 700 people and operating in more than 40 countries worldwide. The business is still owner run and has its headquarters in Neumarkt, Bavaria.

At the Neumarkt site, non-sterile liquids are filled and packed in glass bottles on two liquid lines for therapeutic nose, throat and lung applications. To improve the overall equipment effectiveness of its liquids production, Bionorica decided to automate

DID YOU KNOW?

Bionorica is mainly known for Sinupret – Germany’s number one cold remedy in terms of sales.

The product is also available internationally, including South Africa.

various steps that were previously manual. In addition to depalletising and the unpacking of foil-sealed ‘safe packs’ – the feeding and inspection of bottles are now fully automated.

The idea is that, in future, all modules on the line will deliver the same high level of performance. Although the filling machine theoretically has a maximum output in the region of 200 bottles per minute, this figure has never actually been reached in practice because the machine’s capacity has so far been unmatched by the performance of the other modules, notably the cartoner. This is why Bionorica opted to replace every module on the line apart from the filling machine.

The internationally successful remedy, Sinupret, on the automated liquids line at Bionorica

cartoner subsequently packs the bottles into cartons together with a leaflet. Finally, they are serialised with a 2D code and packed into cases, sealed and serialised again by a case packerpalletiser, before being automatically loaded onto pallets at the end of the line.

Four of the modules on the new packaging line are from the Karlsruhe-based Romaco Group, which develops, manufactures and distributes GMP compliant, high-tech system solutions for the pharma industry.

‘Romaco has a broad, premium quality product portfolio – which is a great advantage when implementing complex plants like ours. It means we can source several machines from just one supplier,’ explains Howard Fick of Bionorica’s engineering department. ‘The supplier also convinced us with the offering of good value for money solutions, individually tailored to our needs and its prompt and efficient support.’

A LOOK AT THE PROCESS In the first section of the fully automatic liquids line, the glass bottles delivered in safe packs are automatically depalletised and unpacked with the help of a Romaco Macofar MED 003 depacking system. They are then passed to an inspection unit, featuring a new technology jointly developed by Romaco and Bionorica, for detecting and removing faulty bottles.

In the next step, the bottles are fed via a rotary table to the filling machine, where they are filled, fitted with a screw cap and labelled. A Romaco Promatic PC 4250 continuous motion

28

| QUARTER 3 2019 | P C Africa

The Romaco Promatic PC 4250 continuous motion cartoner packs bottles into cartons

PACKAGING MACHINERY

Once the safe packs have been depalletised, the Romaco Macofar MED 003 depacking machine cuts open the thermoshrink plastic packaging material with three heated, moving blades. Unlike conventional depacking systems, the MED 003 has a separate servo motor for every single movement, allowing for the individual programming and storage of unpacking parameters for any safe pack type. The format change time – Bionorica uses 30, 50 and 100mℓ bottle sizes – is significantly reduced because far fewer format parts have to be replaced with the MED 003 compared to other depacking machines with a single, central motor.

TAILORED SOLUTION PREVENTS DAMAGE To prevent damage to the filling machine due to faulty bottles, Bionorica collaborated with Romaco to develop a simple, space saving solution for monitoring empty bottles. This inspection unit, named Spectra, is necessary because the manufacturer uses blow moulded glass bottles as primary packaging for its medicines. About one to two percent of these containers are

Bionorica trusts Romaco technologies, when it comes to packaging its Sinupret drops

outside the tolerance range i.e. they are not exactly vertical, or the

maintenance,’ comments Gerhard Garthe, area sales manager

bottom is too thick. In the past, these bottles regularly damaged

at Romaco. Garthe is also responsible for providing support for all

the filling machine, resulting in lengthy stoppages.

Romaco technologies installed at Bionorica.

‘An inspection unit capable of meeting our requirements and

‘In practical use, the PC 4250 completes toolless format

with damage prevention as its sole purpose, didn’t yet exist. This is

changes in under 30 minutes and stack heights can be modified

why we decided to collaborate with Romaco on designing a new

in less than 10 minutes,’ he adds.

solution,’ Fick reports. ‘Not only is Spectra an exact fit and answer

Each of the cartoner’s drives has its own torque limiter, whether

to our needs, it was also much more cost-effective than any of the

it’s for the infeed conveyor, erection unit or the various closing

standard products on the market. The standard products were

groups. This is especially important on bottle lines where individual

also way too complex for our needs.’

components are subjected to very heavy loads.

CARTONER WITH TWO SPEEDS

the cartoner to Bionorica’s highly specific needs. It was important

The Romaco Promatic PC 4250 was integrated into Bionorica’s

for the cartoner to operate at two different speeds. In normal

liquid line as an advanced cartoning module. It has no problem

operation, the packaging line achieves around 200 bottles per

keeping pace with the filling machine.

minute, which is consistent with the performance limit of the

‘Aside from the very short ramp-up phase, the PC 4250 impresses with its ease of handling and straightforward

Romaco’s customising expertise came in hand while tailoring

filling machine. However, if the cartoner stops briefly because of a stoppage on a downstream machine, bottles collect ahead of it on an accumulation table. They are detected by the sensors installed in the cartoner and the speed is then temporarily increased to 240 cartons per minute, to enable the backlog to be cleared. As a result, the filling machine upstream from the cartoner is not required to interrupt operation and there is no loss of performance on the line as a whole.

INCREASED PRODUCTIVITY The new liquids line has been up and running at Bionorica in the final configuration since July 2018. As soon as all the settings are optimised, Bionorica predicts an increase in its productivity of roughly 20 percent compared to the old line.

The company’s second liquids line is about to be upgraded in the same way – starting with another Romaco Promatic PC 4250 cartoner, which is in the process of being commissioned at Bionorica. In future, the Bavarian pharmaceutical manufacturer’s complete range of liquid products will be packaged using Romaco technology. •

Romaco – www.romaco.com

P C Africa | QUARTER 3 2019 |

29

PACKAGING MACHINERY

How to implement AI in manufacturing By developing Forpheus, the world’s first robot that plays table tennis, Omron demonstrates how AI can be incorporated into machines in a packaging environment.

C

areful consideration is

• W hether you have

required before deciding

enough data, which

whether cloud or edge

data is the most

computing would be

relevant and how will

the most effective solution for manufacturing facility, taking into account the recent arrival of artificial intelligence (AI) and machine

it be used • T he cost of the infrastructure • T he problems to

learning. Forpheus embodies

be solved and the

Omron’s three-fold philosophy for

increase in efficiency

innovative automation: integration,

achieved by the use of

WEIGH UP THE OPTIONS

interaction and intelligence,

cloud or edge computing.

Advances in technology have resulted

specifically AI. The robot uses its

Some manufacturing facilities might

in access to machine control equipment

Using AI in a manufacturing environment has its benefits

cameras and sensors to assess

decide to send all data to the cloud.

that process and recognise patterns

an opponent’s play, determining

Large IT companies promote the

within the data. Although edge

their skill level and modifying its

cloud as ‘the solution to everything’.

computing has some distinct differences

own play to make the game of

According to Omron, the cloud isn’t

to cloud computing in the manufacturing

table tennis more challenging.

a complete panacea, as it doesn’t

arena, it doesn’t have to be a complete

This is an example of how smart

show or respond in real time to what’s

substitution. The two can co-exist. In

machines could be used to train and

actually happening on a line. This is why

some situations, computing might take

assist people in a manufacturing

Omron is focussing on AI. Manufacturing

place in the cloud and be transferred to

environment, making the most of

companies are increasingly recognising

edge devices.

their potential.

that AI can make a major contribution

Both cloud and edge computing

to their profitability by increasing overall

HELPING THE HUMAN BRAIN

play a valuable role in manufacturing,

equipment effectiveness, leading to

especially in factories starting to use

Packaging machines within a factory

greater productivity and reducing costs.

AI. Yet, edge computing does appear

are a potential source of valuable data.

AI can have direct and immediate

superior when it comes to using AI on a

But how can you access and analyse

benefits, because the intelligence is

packaging line. •

this data? How can a factory use

incorporated within the machine rather

this data effectively, especially

than being located elsewhere. Users can

when introducing AI to enhance its

focus on potential issues in a process,

capabilities? To answer these questions,

using real time data from the system and

you need to understand the following:

its components.

Omron South Africa – www.industrial.omron.co.za

Superior image sensing speed and precision FH Series

• High-precision object detection • Ultra-high-speed searching • Flexible functionalities to provide high compatibility with manufacturing machines

Would you like to know more? +27 (0)11 579 2600 info.sa@eu.omron.com industrial.omron.co.za fh_series_177x65_ad_enza_01.indd 1

30

| QUARTER 2 2019 | P C Africa

11-06-18 09:42

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