Pharmaceutical & Cosmetic Review Africa Q1 2022 by New Media B2B

AFRICA Quarter 1 2022 | Volume 7 | 01

www.pharmacos.co.za

PHARMA FOCUS THE EVOLUTION OF TABLET COATINGS

BEAUTY INNOVATIONS FORMULATING WITH INVERSE EMULSIONS

PACKAGING

CODING AND MARKING WITH MINIMAL ENVIRONMENTAL IMPACT

Curl care

Formulation hacks for healthy natural hair

AFRICA www.pharmacos.co.za

Quarter 1 2022 | Volume 7 | 01

PHARMACEUTICAL & COSMETIC REVIEW AFRICA

CONTENTS 6

Innovative hair care

that celebrates individuality

NEWS

Natural astaxanthin meets changing demands for health supplements Symrise announces expansion in Grasse

21 BEAUTY INNOVATIONS Bio-based surfactants drive the transition to renewable carbon

Rotocon appointed EyeC inspection systems distributor in South Africa

Provital journeys towards circular beauty with Pomarage

10 HAIR CARE

AECI showcases the various benefits of inverse emulsions

IMCD celebrates consumers’ individuality with innovative formulas Botanichem addresses formulators curl care challenges

26 FRAGRANCES

Discover the power of global scents with Düllberg Konzentra

Sederma restores original hair pigmentation with Silverfree peptide

16 PHARMA FOCUS: TABLETING & ENCAPSULATION

28 PACKAGING

Explore the evolution of tablet coatings with Quantum Colours Introducing the all-in-one tableting solution, Kollitab DC 87 L

Improve coding and marking while reducing your environmental impact How to overcome challenges in sustainable packaging manufacturing

3D screen-printing technology to improve drug delivery

The evolution of tablet coatings 28

Improve coding and marking while reducing your impact on the environment P&C AFRICA // QUARTER 1 2022

PHARMACEUTICAL & COSMETIC REVIEW AFRICA

FROM THE EDITOR

THE TEAM EDITORIAL

Editor: Abby Vorster +27 (0)11 877 6038 abby.vorster@newmedia.co.za Layout & Design: Andipha Nkoloti Sub-editor: Katrien Smit Contributors: Anele Ntuli, Lonsdale O’Donovan, Thorsten Cech, Sithembiso Dlalisa

Up your game when formulating for curly hair

aturally curly is beautiful, especially on

tablet coatings while highlighting the advantages of

good hair days. It gets all the compliments

this tablet manufacturing technique. Next up, BASF

and yet managing curly hair is a dread. I

discusses how a modern co-processed excipient can

have naturally wavy hair which I straighten

simplify drug product production and support cost-

daily, but my mom and sister have the most incredibly beautiful thick auburn curls – which they say is a

optimised manufacturing. Upcycling is the latest buzzword in the beauty

challenge to manage. For them and every other person

industry, with many ingredients suppliers looking

with curly hair, the thin line between untameable locks

into re-using discarded natural waste such as coffee

and good hair days is a good hair care routine with the

grounds or fruit peels for the production of cosmetic

right products.

ingredients. We take a look at this concept in the

In Africa, it is said that many consumers struggle

section on beauty innovations. Turn to page 22 to

to find suitable products for their hair care regime.

read about how Provital upcycles apple pomace – a

These include a moisturising and detangling shampoo,

byproduct of apple cider production – to produce the

rinse-off conditioner that repairs the hair, as well

skin care active ingredient, Pomarage.

as a shine lotion, hair food, scalp treatment and oil

Düllberg Konzentra takes centre stage in the

moisturiser. When designed with the right ingredients,

fragrances feature as we explore the fragrance

these products will enhance and benefit curly hair.

house’s new trend concept – “Feel the World”.

We address this challenge for formulators in our Q1

This trend concept consists of portfolio of sensual

edition of Pharmaceutical & Cosmetic Review Africa.

fragrance experiences inspired by souvenirs from

IMCD South Africa is featured on our cover to

around the world. The scents are best suited for body

showcase its recent hair care roadshow in which the

care formulations, such as a shower

company’s technical team took to the streets to find

bar or bath steamer, to send

out more about the hair care needs of “curlies”. Turn

consumers on a sensual global

to page 10 to read about its focus group meetings

journey. Turn to page 26 to read

with African consumers and the bespoke curl care

more about this.

formulations designed by the technical team to meet their hair care needs.

I hope you enjoy this edition!

Considering the major focus of pharma manufacturing in Africa is on tablets and capsules, our pharma focus on page 16 explores new developments

ADVERTISING Sales Executive: Carla Melless +27 (0)83 260 6060 carla.melless@newmedia.co.za Sales Executive: Anita Raath +27 (0)82 976 6541 anita.raath@newmedia.co.za Sales Executive: Candida Giambo-Kruger +27 (0)71 438 1918 candida.giambo-kruger@newmedia.co.za INTERNATIONAL SALES Germany/Austria/Switzerland: Eisenacher Medien Erhardt Eisenacher +49 228 249 9860 info@eisenacher-medien.de Italy: Ngcombroker Giacomo Rotunno +39 370 101 4694 g.rotunno@ngcombroker.com Taiwan: Ringier Trade Media Sydney Lai +886 4 2329 7318 sydneylai@ringier.com.hk CIRCULATION Circulation Manager: Felicity Garbers felicity.garbers@newmedia.co.za PUBLISHING TEAM General Manager: Dev Naidoo Production Controller: Mandy Ackerman Art Director: David Kyslinger JOHANNESBURG OFFICE New Media Publishing, Ground floor 272 Pretoria Avenue, Randburg Tel: +27 (0)11 713 9000 POSTAL ADDRESS PO Box 784698, Sandton, Johannesburg, 2146 Published by New Media, a division of Media24 (Pty) Ltd. MANAGEMENT TEAM MANAGING DIRECTOR: Aileen Lamb COMMERCIAL DIRECTOR: Maria Tiganis BRAND STRATEGY DIRECTOR: Andrew Nunneley CHIEF FINANCIAL OFFICER: Venette Malone

in tableting and encapsulation. On page 16, Quantum

CEO: MEDIA24: Ishmet Davidson

Colours takes readers through the evolution of

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Cape Town, 8001

AECI Specialty Chemicals..............................25....................... www.aeciworld.com/ specialty-chemicals Botanichem .....................................................13........................ www.botanichem.co.za Chempack Industries......................................12........................ www.cpack.co.za Croda SA ..........................................................15........................ www.crodapersonalcare.com Düllberg Konzentra..........................................27........................ www.duellberg-konzentra.de IJP Filling & Labelling.......................................IFC...................... www.labelling.co.za IMCD SA ............................................................OFC.................... www.imcdgroup.com Mitas Corporation ...........................................29....................... www.tracepack.co.za Omron Electronics ...........................................30....................... industrial.omron.co.za Quantum Colours SA ......................................17........................ www.quantumcolours.com Savannah Fine Chemicals..............................23....................... www.savannah.co.za Sensetek ...........................................................26....................... www.sensetek.co.za Telstar ................................................................19........................ www.telstar.com Vega Controls SA ............................................5.......................... www.vega.com/vegapoint

Email: newmedia@newmedia.co.za

Tel: +27 21 406 2002 PO Box 440, Green Point, Cape Town 8051

Pharmaceutical Cosmetic Review Africa is published by New Media four times a year and circulates to manufacturers, packers and distributors of pharmaceuticals, health products, cosmetics, detergents, soaps, toiletries and allied products. The journal is an up-to-date source of reference for company directors, factory and production managers, marketing executives, engineers, import agents, buyers and research personnel. While precautions have been taken to ensure the accuracy of its contents and information given to readers, neither the editor, publisher, or its agents can accept responsibility for damages or injury which may arise therefrom. All rights reserved. © Pharmaceutical Cosmetic Review Africa. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, photocopying, electronic, mechanical or otherwise without the prior written permission of the copyright owners. Pharmaceutical

Cosmetic Review Africa is printed by Tandym.

QUARTER 1 2022 // P&C AFRICA

We bring colour into view! Compact capacitive level switches with 360° custom-colour status display

256 colours Individually selectable: Measurement in progress Sensor switching Process malfunction

15 cm

Compact design

Hygienic adapter system

Adjustment via smartphone

www.vega.com/vegapoint

NEWS

Natural astaxanthin meets changing demands for health supplements PREVENTIVE HEALTH MEASURES

of cell membranes, thus protecting

and immune support continue to

cells and their powerhouses

be of major importance to people

(mitochondria) from oxidative stress.

worldwide. The same applies to

In doing so, astaxanthin can boost

the demand for plant-based and

muscle endurance, counteract fatigue,

personalised diets. At Vitafoods

reduce inflammation, improve skin

Europe 2022 from 10 to 12 May,

texture and enhance capillary blood

natural astaxanthin pioneer AstaReal

flow in the eyes, as well as the brain.

will be focusing on ingredient

cold water-dispersible powder, or

consumer concerns.

oil extract, AstaReal offers natural

With its AstaGummy Boost that

Omya set to grow in Asia Pacific with the acquisition of Prima Inter-Chem A LEADING GLOBAL producer of industrial minerals, Omya has acquired the distributor Prima Inter-Chem, which is based in Malaysia and Indonesia. With this move, Omya will boost and develop its ingredient and speciality chemicals distribution capability for the food, pharmaceutical, animal feed and industrial markets. In addition, the acquisition will see Omya establishing a platform for growth in

Whether as algal biomass, a

solutions that address these

astaxanthin in many different forms.

delivers the antioxidant in an easy-

Diverse processing options and

to-swallow gummy format and its

possibilities allow for the combination

vegan softgel capsules, the company

of astaxanthin with other ingredients,

is tapping into new target groups in

such as vitamins, minerals, pro- and

order to meet the needs of consumers.

prebiotics and plant extracts, in a

AstaReal astaxanthin serves several current trends at the same time. Derived from the microalga

liquid shot, soft gummy, sachet or capsule format. Peter Ahlm, marketing and sales

Haematococcus pluvialis, astaxanthin

manager at AstaReal, says: “Stable

is both a natural carotenoid and

immune health, plant-based or

sustainable nutrient that aligns with

personalized nutrition are all topics

emerging, plant-based trends. Almost

that are driving consumers and thus

at the bottom of the marine food

our customers. People are more

chain, microalgae supply fish and krill

willing than ever to look closely at

with astaxanthin and omega-3 fatty

ingredients that help them achieve

acids, and yet it is a sustainable and

their holistic health goals.

vegan alternative to both. Backed by more than 70 human

At the same time, they are demanding sustainable products

clinical studies, AstaReal astaxanthin

as they are considered better

demonstrates numerous benefits for

and healthier.

the growing demography of healthy

With natural astaxanthin in its

agers. Its unique structure enables

many different delivery formats, we

natural astaxanthin to target free

can meet these demands in the best

radicals in the inner and outer layers

possible way.” •

the wider region. This is another success story of Omya’s strategy to acquire complementary businesses. Prima and Omya share the same values and business approach of helping customers and principals expand their market reach, both internationally and throughout the Asia Pacific region. Omya’s existing capabilities in Asia Pacific will be strengthened by the exceptional knowledge, experience and expertise that Prima brings to the organisation. Omya looks forward to welcoming the impressive team at Prima into the group. Khoo Kah Pheng and Lim Kooi Fui, founders and shareholders of Prima Inter-Chem say: “We are very pleased to have found a great haven for the team and business we have built over the last 38 years. We believe that Omya is the best partner to take Prima to the next level of growth and success in Asia.” •

QUARTER 1 2022 // P&C AFRICA

Astaxanthin in production at the AstaReal plant. Astaxanthin is what gives the pink and red colour to salmon, shrimp and lobster

NEWS

Glatt to inaugurate vaccine production in Ghana with fill and finish plant GLATT IN WEIMAR, Germany has been

Africa is to be developed. As a process

commissioned to conduct a concept

expert and working in close collaboration

occupy 7 000m2, encompassing various essential

study to investigate the technical and

with the vaccine manufacturer, Glatt will

areas on different floors. These include the warehouse

economic aspects of a fill and finish

provide detailed planning services for the

and logistics level, a mezzanine for changing rooms

plant for vaccines. The independent,

plant, investigate its technical feasibility

with an adjacent canteen and a floor for administration

fully integrated state-of-the-art

and provide economic efficiency advice.

and technology. The heart of the facility, the

biotechnological facility is to be built in

The current planning envisages the filling

production level, will comprise two preparation and

Accra, Ghana, and will lay the foundation

of vaccines in four independent production

formulation units for different vaccine categories (up

in the region for vaccine production

modules. Single-use components for

to biosafety level 1), a R&D area and quality control

against COVID-19 and other diseases.

different primary packaging materials will

laboratory. After the successful completion

be used.

of all phases, the plant will be

The current pandemic has underscored the need for vaccine production in

The plant will be operated by DEK

The main building and administration wing will

able to fill at least 100m

Africa. Through government’s vaccine

Vaccines, a company founded by three

vaccine doses per shift,

development and manufacturing

pharmaceutical manufacturers based

per year. •

presidential committee

in Africa. The project comprises three

(VMC), Ghanaian President Nana Addo

phases, which will be implemented

Dankwa Akufo-Addo has convened a board

on a step-by-step basis. The specific

to establish a 10-year plan for vaccine

requirements for the manufacture of

development and production. The most

current and future products are already

promising near-term approach to achieve

being incorporated into Glatt’s planning to

this goal is the construction of a bottling

ensure a smooth production process. The

and packaging plant. On this basis, further

same approach is being applied to legal

capacity for full vaccine production in

conditions and standards.

An artist’s impression of the state-of-the-art biotechnological facility, to be built in Accra, Ghana

Symrise announces expansion in Grasse, the French perfume capital SYMRISE HAS SUBMITTED a binding offer to

Symrise intends to build a strong player in

“We are very pleased about the offer to join

acquire 100% of R. Romani – Société Française

the Grasse area with a new growth platform

such an important Group as Symrise. Customers

d’Aromatiques (SFA Romani), a high-end fragrance

including creation centres, sales and marketing

and employees of Neroli will be in very good

house. In addition, Symrise submitted a binding offer

teams, as well as production capacities.

hands which will be most important for me”, said

to fully acquire Neroli Invest DL (Groupe Neroli). Both companies are based in the Grasse area in France. With these transactions, Symrise intends to

SFA Romani, founded in 1963 in Grasse, is finest natural raw materials, its craftmanship

reinforce its fine fragrance presence in southern

in fragrance creation and the quality of its

France, strengthen its competitiveness in the

compositions. In almost 60 years, the company

creation of fragrance compositions and broaden

has developed unparalleled know-how in high-

its presence in key countries in Europe, Africa

end fragrance compounds.

and the Middle East. The combined annual sales

“We are very proud of all that SFA Romani has

of SFA Romani and Groupe Neroli amount to

achieved in 60 years as an independent company.

more than €40m. The closing of the transactions

We embody unparalleled know-how and quality in

is expected in Q2 2022, subject to approval of

high-end fragrance compounds from Grasse. We

respective bodies and consultations of the works

are confident that the company and our brand will

councils. The parties agreed to keep the purchase

continue to flourish as part of the Symrise family,”

price confidential.

said Viviane and Charles Romani-Caruso, founders

Ricardo Omori, global SVP fine fragrance of Symrise, comments: “With these transactions,

Christian Dussoullier, CEO of Neroli group. •

internationally recognised for its choice of the

of SFA Romani founders. Groupe Neroli consists of the companies

we will increase our access to high-quality

Creations & Parfums and Floressence, both

natural ingredients, expand our customer base

founded in the mid-1980s in St. Cezaire within

and strengthen our competitiveness through

Pays de Grasse. Last November, Symrise had

greater agility and a significantly enlarged fine

already announced a joint venture with Groupe

fragrance team in the historical birthplace of

Neroli. Now, the company decided to fully

perfumery in Europe, Pays de Grasse.”

acquire the shares.

To build a strong position in natural fragrance ingredients, Groupe Neroli established long-term partnerships with farmers in the Grasse area for the sustainable cultivation of flowers

P&C AFRICA // QUARTER 1 2022

NEWS

Rotocon appointed EyeC inspection systems distributor in South Africa ROTOCON HAS BEEN appointed the exclusive EyeC distribution

New entrant to develop and support cosmetic and skin care entrepreneurs

partner in South Africa for its range of innovative artwork and print

Cosmetics industry expert, Robyn Brown

inspection systems. EyeC attended Propak Africa with Rotocon to meet industry professionals and showcase its ProofRunner Web inline inspection system. The trade show took place from 8 to 11 March

The company is also planning

in Johannesburg, South Africa,

to create ‘kits’ for popular skin

“Over the last 20 years, EyeC has built a reputation of providing

care and personal care products

reliable, high-quality inspection systems to help customers implement

for those who do not have

rigorous quality control processes and ensure compliance,” said

experience in formulating.

Michael Aengenvoort, Rotocon group CEO. “Its range of automated

The other side of the

inspection systems will be of great benefit to South African printers

company is to provide

throughout the entire cycle of their production process.”

information and advice on the

Ralph Beier, sales director at EyeC, adds: “We are very pleased to

basic principles of formulation

add Rotocon to our global distribution partner network. The company’s

and skin care production

knowledge of the print industry and exemplary coverage of the South African market coupled with an experienced technical support team made appointing Rotocon as our partner an easy decision.” Founded in 2002 in Hamburg, Germany, EyeC is the market’s only supplier to ensure the product quality throughout the entire printing process – from the first artwork file to the finished product. The product portfolio includes file-to-file comparison for artwork revision control and prepress applications, as well as print-to-file inspection systems for press sample testing and 100% print quality control of products such as folding cartons, labels, leaflets, or flexible packaging. Worldwide, there are over 1 800 EyeC inspection systems in use by pharmaceutical companies, printers and branded goods manufacturers. With EyeC products, users avoid recalls, keep production costs and material waste in check and optimise their quality control. •

to industry newcomers THE PERSONAL CARE Coach

with a view to launching

and Training Company is a

certified training courses for

new venture by well-known

compounders, formulators

industry expert Robyn Brown,

and entrepreneurs.

who through her work in the

my work and interaction with

for a venture that is focused

entrepreneurs, I have seen

on developing and supporting

firsthand the need within

emerging small cosmetics and

the cosmetic industry for an

skin care businesses.

accredited course that will

Brown describes the

players with the opportunity

Training Company as a

to learn how to make

one-stop shop for aspiring

cosmetics,” she explains. offer compounders, formulators

There are two sides to

and industry entrepreneurs,

the company:

who either do not have any

1. to supply ingredients and

other cosmetic and toiletry

2. to provide advice and accredited training.

training or do not qualify for other courses currently available, the opportunity to

“The concept is to provide

improve their skills and get an

support to small- and

accredited qualification.

medium-size enterprises

The courses will cover the

that want access to the same

basics of formulation; what

quality cosmetic actives,

equipment to use and how to

ingredients and raw materials

use it.

as their larger counterparts,” says Brown. The Personal Care Coach focuses on supplying these ingredients in smaller pack sizes

QUARTER 1 2022 // P&C AFRICA

The training courses will

entrepreneurs and businesses.

raw materials

provide new and existing role

Personal Care Coach and

skin care and cosmetic

Ralph Beier, sales director at EyeC, with Michael Aengenvoort, Rotocon group CEO at Propak Africa 2022

“Over the years, through

industry, identified the need

The Personal Care Coach and Training Company expects to be up and running by the end of March. For more information,

that are affordable and accessible

please send Robyn Brown a

to start-ups and SMMEs who do

WhatsApp message on

not require large quantities.

+27 (0)84 599 0063. •

WHAT'S ON IN

DIARY

2022

April

in-cosmetics Global

5 to 7 April Paris, France www.in-cosmetics.com/global

SAPHEX

6 to 7 April Joburg, South Africa www.saphex.co.za

Labelexpo Europe

26 to 29 April Brussels Expo, Belgium www.labelexpo-europe.com

May

Propak East Africa

10 to 12 May Nairobi, Kenya www.propakeastafrica.com

Vitafoods Europe

10 to 12 May Geneva, Switzerland www.vitafoods.eu.com

June Analytica

21 to 24 June Munich, Germany www.analytica.de/en

2022 World Perfumery Congress

29 June to 1 July Miami, Florida www.worldperfumerycongress.com

P&C AFRICA // QUARTER 1 2022

HAIR CARE

– addressing Curl care the challenge for formulators

Curly hair requires special care due to its unique structure. This is even more the case for ethnic hair types. Curly hair in general lacks moisture and dries out easily. The reason for this lies in the physical structure of curly hair. Formulators and manufacturers need to understand the makings of hair curly in order to design products that will enhance and benefit the hair type.

HE SCIENCE OF hair shape holds the key to effective hair care

throughout the hair. Whilst this means people with curly hair may not

product formulation – regardless of whether the product

need to wash as often, it can lead to dandruff and scalp irritation,

is intended for straight or curly hair. An article published by

which can cause discomfort.

Northwestern University explains that there are two aspects of the hair’s structure which determine its shape – the shaft and the follicle. Essentially, the shaft is the part of the hair we see growing out of the

When it comes to the hair shaft, it is the way the protein molecules build up on the curly hair that affects how curly the hair is. Proteins such as keratins tend to build up unevenly in curly hair, collecting in

head, whilst the follicle lies within the scalp and is the anchor that holds

the curve of the hair and making it curl even more, although this is

hair in place. The shape of the follicle determines the amount of curl in

less of an issue than the actual shape of the follicle when it comes to

the hair, i.e. a round follicle will produce straight hair, an oval follicle will

affecting curliness.

result in wavy hair and an elliptical or hooked follicle produces curly or extremely curly hair. The angle at which hair grows out of the scalp affects the intensity of

SOOTHE, CALM AND NOURISH HAIR Curly and extremely curly hair need extra care, mostly in the form of

the curl. Curly hairs tunnel in at an angle, which also has an impact on the

ingredients that can restore hair’s moisture. Gentle cleansing is also

oiliness of the hair as the angle makes it difficult for natural oils to spread

important in order to manage the occurrence of irritable scalp and the build-up of dandruff. Ingredient manufacturer Cobiosa, which celebrates its 50 th anniversary this year, specialises in the production of botanical extracts from the Andean region and the extraction of natural active ingredients. Included in this offering is a range of ingredients for the hair care industry. Cobiosa has identified two particular ingredients which are ideal for inclusion in products for curly and extremely curly hair. Ethomega is an exotic and exclusive oil mix combining the soothing and antioxidant properties of chia seed oil with the powerful nourishing properties of sacha inchi oil. Ethomega contains a very high content of polyunsaturated fatty acids and tocopherols. It helps to: • reduce split hairs and breakage

QUARTER 1 2022 // P&C AFRICA

• restore the scalp and hair barrier

The Jatropha macrantha plant

HAIR CARE

Table 1: Perfect curls gentle shampoo

Phase

Raw material Water

% 54.77

Propanediol

5.00

Dermasoft OMP

3.00

Varisoft EQ 100

0.70

Bentone Hydroclay 2000

0.20

Cosmedia Guar

0.30

Dehyton PK

5 6

20.00

Dehyquart C4046

5.00

Ethomega

5.00

Covi-ox T70C

0.40

Protecsyl

5.00

Emulgador CH 8717

0.20

Perfume

0.10

Lactic Acid Solution 20%

0.33

Total

100.00

Raw material Water

3 4

% 71.00

Glycerin

2.00

Dermosoft OMP

3.00

Varisoft BT 85

5.00

Dehyquart C4046

5.00

Lanette 16

3.00

Ethomega

5.00

Covi-ox T70C

0.50

Protecsyl Parfum Total

Cobiosa’s version of the “curly girl method” includes a list of dos and don’ts and ingredients to avoid and embrace to achieve perfect curls and healthy, extra nourished hair.

DOs

DON’Ts

• Cleaning: clean using a conditioner or cream shampoo with natural emollients.

• Don’t use sulfates.

• Moisturise using humectants such as glycerine and nourishing oils.

• Don’t use heat, it severely damages the hair.

• Create curl definition and styling with leave-on formulas to boost hair wellness, hydration and avoid frizz.

• Don’t use non-soluble silicones.

• Don’t use drying alcohols.

• Seal with natural and nourishing oils.

• increase brightness

and elasticity and

• protect hair colour

improving weak and

• improve scalp comfort by calming the

breakable hair. Protecsyl

itching sensation • restore moisture.

helps to: • prevent frizz • protect and preserve hair proteins

Table 2: Hair mask hydration boost

Phase

COBIOSA’S CURLY GIRL METHOD

PROTECTING THE INNER HAIR ARCHITECTURE

• repair split ends

The second ingredient, Protecsyl, is an

• prevent hair breakage

extract from the Jatropha macrantha plant,

• protect hair colour

which is indigenous to Peru.

• protect the inner architecture of the hair.

Curly and extremely curly hair need extra care Protecsyl is an exotic active

• strengthen the hair

Used together, Ethomega and Protecsyl are ideal for gentle cleansing shampoos, hair masks, hair cream and split-end sealing treatments. Both ingredients are available throughout Southern Africa from Botanichem. Check out the formulation guides in tables 1 and 2 for more information on these

ingredient designed to protect the

suggested formulas or chat to Robyn Brown at

5.00

inner hair architecture and prevent

Botanichem for guidance. •

0.50

protein degradation.

100.00

It preserves the cell membrane complex, supporting hair resistance

Botanichem – www.botanichem.co.za Cobiosa – www.cobiosa.com

P&C AFRICA // QUARTER 1 2022

HAIR CARE

Embracing individuality and restoring confidence with Silverfree Well-ageing and self-care trends are seeing an increased need in the market for hair products that help consumers look younger and more vibrant while embracing their natural beauty. Silverfree is Croda’s solution for those who want the freedom to be authentic when it comes to their hair. By Anele Ntuli of Croda SA

UMAN BEINGS COMMUNICATE in many ways. Non-verbal methods of communication tend to be very

successful, especially within large groups of people of different backgrounds and ethnicities. Typically, non-verbal communication is thought to include sign language, symbols, totems and other written forms. Yet, communication actually starts at home when people get ready to face the day. For centuries, choice of clothing and hairstyling have been used to pass messages amongst mankind. Especially in Africa, hairstyles have significant relevance in religious, cultural, tribal and social settings. Hairstyle messaging is often widely understood; the significance and meaning of a particular hairstyle may differ depending on the context. For example, in many social groups, women are required to cover their heads to show respect, modesty or even mourning.

Nowadays, society is changing and consumers are using their hair to express their individuality rather than conform to traditional norms. This is evident in the latest research from Mintel on hair colourants, which states that the number of 16-

Did you know? Silverfree works in both preventive and corrective ways. It prevents premature hair greying and blurs any greying hair demarcation line, allowing re-pigmentation.

to 24-year-old men using hair colourants grew by 8% from 2018 to 2019.2 Hair has the ability to communicate power, status, influence and romantic availability (mostly in women) in addition to cleanliness, financial

that help their hair appear more vibrant and help them look younger, with a particular emphasis on embracing natural beauty.4 The onset of hair greying differs according

status and orderliness – because beauty really is

to ethnicity: mid-30s in Caucasians, late 30s in

in the eye of the beholder.

Asians and mid-40s amongst Afro demographics.5

How then, does grey hair affect the way

Figure 1

Scientific research has proven that the greying of hair is not only a consequence of old age. Lifestyle,

melanin which expresses the colour seen in eyes,

external influences and genetics have a great effect

skin and hair. This process occurs in the hair

MANAGING GREY HAIR WITH SMART SCIENCE

on hair pigmentation. This is why Sederma has used

bulb where cells actively divide and only occurs

smart science to offer an innovative approach to

during the Anagen or hair growth phase. Melanin

Grey hair is universally perceived to be a sign of

managing grey hair, promoting hair freedom and

granules are transferred into the cortical and

ageing. This can have detrimental effects on one’s

exclusive beauty.

medulla keratinocytes, resulting in the formation of

people communicate with others?

self-esteem, especially in cases of premature

Silverfree™ by Sederma helps individuals

pigmented hair shafts.6 Melanin only represents 1%

greying. In a world where people are living longer

embrace their natural beauty by re-educating hair

of the composition of hair and is formed from the

due to advances in medicine, society is ageing

bulbs to produce their authentic hair pigmentation.

enzymatic conversion of tyrosine by tyrosinase to

and “well-ageing” claims are steadily increasing.

Melanogenesis is the process that controls all

form insoluble polymeric pigments, eumelanin (dark

Consumers are constantly looking for products

human pigmentation. Melanocyte cells produce

pigment) and pheomelanin (light pigment).7

QUARTER 1 2022 // P&C AFRICA

HAIR CARE

Figure 2

Sederma has used smart science to offer an innovative approach to managing grey hair

PROVEN EFFECTIVE WITH FAVOURABLE NATURAL CONTENT

protects the cells against oxidative damage

Now that we know the science behind natural

exposome, ensuring melanocyte function

hair colour, it’s important to understand how

integrity. Its efficacy has been proven in vitro and

Silverfree works. This biomimetic peptide

is validated in four independent clinical studies.

supports the progressive restoration of original

induced by the cellular metabolism and the

Silverfree helps visibly reduce the density of

hair pigmentation with a remnant effect while

white hair (from 32.4% to 86%) and helps recover

protecting it from oxidative damage.

original hair colour (an increase in pigmented

The biomimetic peptide lasts for up to four

hair from 27.4 % to 385%) – see Figure 2. It

months after the last application, triggering

has a natural origin content of 99.4% and is a

overexpression of the key pigmenting genes, and

formulator’s dream as it is easy to incorporate

reactivates melanocyte function (see Figure 1).

in formulations. Silverfree is water-soluble, fully

Silverfree also promotes hair repigmentation

cold-processable and recommended for use at

by stimulating dendrite elongation, improving

1.5%. It is recommended for all types of hair care

melanosome recruitment into keratinocytes.

products such as masks, hair sprays, oils, serums,

By boosting cells’ inner defence, Silverfree

conditioners and waxes. 8 •

SILVERFREE

References: 1. Yussuf, T. and Yussuf, T., 2022. African Hair and Communication - Omenka Online. [online] Omenka Online. Available at: <https://www.omenkaonline.com/african-hair-communication/>. 2. Team, M., 2022. Four in ten UK 16-24-year-old men use hair colourants. [online] Mintel. Available at: <https://www. mintel.com/press-centre/beauty-and-personal-care/ reach-for-the-bleach-four-in-ten-uk-16-24-year-oldmen-use-in-home-hair-colourants>. 3. Kumar, A., Shamim, H. and Nagaraju, U., 2018. Premature graying of hair: Review with updates. International Journal of Trichology, 10(5), p.198. 4. Team, M., 2022. Hair colourants drive innovation in hair care globally. [online] Mintel. Available at: <https://www.mintel. com/press-centre/beauty-and-personal-care/global-hair-colourant-market-trends>. 5. Maymone, M., Laughter, M., Pollock, S., Khan, I., Marques, T., Abdat, R., Goldberg, L. and Vashi, N., 2021. Hair Aging in Different Races and Ethnicities. NCBI, [online] 14(1), p.1. Available at: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869811/>. 6. Slominski, A., Wortsman, J., Plonka, P., Schallreuter, K., Paus, R. and Tobin, D., 2005. Hair Follicle Pigmentation. Journal of Investigative Dermatology, 124(1), pp.13-21. 7. Deckner, G., 2020. Hair Pigmentation and Melanogenesis - Prospector Knowledge Center. [online] Prospector Knowledge Center. Available at: <https://knowledge. ulprospector.com/10385/pcc-hair-pigmentation/>. 8. Crodapersonalcare.com. 2021. Silverfree| Personal Care. [online] Available at: <https://www.crodapersonalcare. com/en-gb/product-finder/product/5464-Silverfree>.

Sederma – www.crodapersonalcare.com

Smart science to improve lives™ SouthAfrica_03-2022_Silverfree.indd 1

16/03/2022 16:00:01

P&C AFRICA // QUARTER 1 2022

PHARMA FOCUS: TABLETING & ENCAPSULATION

The evolution of tablet coatings Applied to various oral dosage forms such as particles, powders, granules, crystals, pellets and tablets, coatings have advanced from an art of earlier years to technologically advanced and controlled processes centred around compliance and good manufacturing practices. By Lonsdale O’Donovan of Quantum Colours

RADITIONALLY, TABLETS WERE sugarcoated. Yet sugar coating is a long and tedious process of building layer upon layer,

followed by polishing, with some variable results in certain cases. The advantage of this process is the fact that the equipment is simple and inexpensive and yields an attractive appearance. Subsequent to sugar coating, film coating became the preferred way of coating tablets. This involved solvents (alcohol or methylene chloride) used with solids. The process was easy but posed a flammable hazard and the equipment had to be flame-proof.

REASONS WHY TABLETS SHOULD BE COATED:

1. A tablet coating gives brand recognition to a tablet by adding colour. 2. A coating can mask an unpleasant taste or smell, such as a B-complex tablet, which can be masked with a flavoured coating. 3. A coating acts as a moisture barrier, protecting active ingredients against oxidisation. 4. Coatings protect the core against light. 5. They can be used to separate incompatible material. 6. A coating is used to hide discolouration of the core over time. 7. By using polymers that are pH specific, a coating can modify drug release. 8. Coating aids structural strength to the core and can increase the hardness of the core by about 60N.

QUARTER 1 2022 // P&C AFRICA

PHARMA FOCUS: TABLETING & ENCAPSULATION

Did you know? The majority of pharma manufacturers in the East African region produce non-sterile products. The major focus is on solids (capsules/tablets), consisting of mainly non-complicated formulations. About 56% of the products manufactured throughout East Africa’s pharma industry are solid dosage forms, mostly tablets. Most of the solids are presented as strip/blister/bulk packs.

Source: African Centre for Technology Studies

Because the coating process has many variables, everything needs to be controlled and correctly done in order to obtain the desired result

Polymer-based coatings yield a smooth, glossy finish on tablets which is easy to swallow and compatible with most active ingredients. Enteric coatings can be based on methacrylic acid copolymers type A, B and C, which are pH specific. The delivery systems can be specific to the jejunum (pH 6.0), colon (pH7.0) and duodenum (pH5.5). Enteric preparations can

Finished tablets also had an undesirable solvent or

be used for targeted-specific drug delivery, or

chemical-like smell. In most instances the solvent

to protect the active ingredients in the tablet

process was replaced with the aqueous-based film

against the acid medium of the stomach.

coatings, which are more challenging to use as the

HPMC-based coatings yield a matte finish

coating has to be applied to the tablets without

and are not as smooth as polymer-based

wetting and could affect the integrity of the tablets.

coatings, though HPMC-based coatings give good moisture protection.

SELECTING THE RIGHT COATING Depending on its required functionality – be it

THE COATING PROCESS

moisture, taste barrier, controlled sustained release

Because the coating process has many

or enteric – a film coating is generally based on a

variables, everything needs to be controlled and

powder blend of different low viscosity, film-forming

correctly done in order to obtain the desired

polymers (PVA) or cellulose (HPMC), plasticisers,

result of an aesthetically pleasing tablet to the

pigments, fillers and flow agents etc. This powder

functionality of the actual coating.

base is then mixed with R/O water or a solvent base, depending on the physical properties of the tablet. It is critical that the correct type of coating is

Some critical parameters begin with the integrity of the raw materials used to manufacture the cores through to the

selected. Solvents are used when rapid drying is

manufacturing process of the tablets and on to

required, especially when hygroscopic material

the processing and coating of the tablets.

is used in the tablet core like some calcium/

Remember, it’s critical to obtain the

magnesium (Ca/Mg) preparations. For a Ca/

recommended weight gain on the cores to

Mg preparation that absorbs moisture from the

achieve the desired efficacy of the functional

atmosphere, one should not select an enteric

coating. To identify and resolve defects

coating as this will compromise the absorptivity as

associated with the coating process, readers

the calcium and magnesium needs to be exposed

are invited to request a complimentary trouble-

to the acidic medium of the stomach in order to

shooting guide in poster format from

activate the minerals to become more bio-available.

Quantum Colours, by sending an email to

The incorrect selection of an enteric coating can

sales2@quantumcolours.com. This detailed

account for an 80% loss in availability of calcium and

poster covers issues such as orange peel, film

magnesium and should not be the first choice.

peeling, picking, twinning, film cracking, logo erosion, film chipping, colour variation, logo

POLYMER-BASED COATINGS

bridging and logo infilling. •

Film coatings based on high molecular weight polymers are safe to use as these cannot be absorbed into tissue. They have no physical action at the recommended dosage and are non-toxic.

Quantum Colours – www.quantumcolours.com

P&C AFRICA // QUARTER 1 2022

PHARMA FOCUS: TABLETING & ENCAPSULATION

Kollitab DC 87 L – the

all-inone tableting solution Accelerating product development to shorten time to market, without compromising on the robustness of a tableting formulation. Maximising the reliability of large-scale tableting processes, while simplifying drug product production allowing for cost-optimised manufacturing at the same time – the targets of a formulator have never been more challenging. Thorsten Cech of BASF SE and Sithembiso Dlalisa of BASF South Africa explore modern co-processed excipients and computer-aided formulation development as effective tools to overcome these demanding tasks.

RADITIONALLY, AN ACTIVE pharmaceutical

projects, respectively. This is the area of conflict

dedicated API? No, surely not. That is not the claim.

ingredient (API) is formulated as an

where both an all-in-one tableting aid and a virtual

All-in-one excipients are optimised to simplify

immediate release tablet by combining

pharma assistant come in handy. Holistically, these

development, increase processing robustness and

various excipients. Each individual excipient

two tools simplify formulation development and free

reduce the overall cost of tablet manufacturing.

addresses a specific need in the overall formulation

up time and resources greatly re-quired.

Indeed, following the concept and utilising all its

concept. Typical requirements are:

overarching benefits provides various advantages

•

increasing the tablet volume with a filler

THE ALL-IN-ONE TABLETING AID

throughout the entire business, such as:

•

improving tablet strength with a binder

Co-processed excipients are well established

•

adjusting the disintegration features by

in the pharmaceutical community. Uniting the

employing a disintegrant

performances and synergies of cleverly combined

lowering the ejection force by selecting an

excipients and the benefits of a dedicated

effective lubricant.

manufacturing process, co-processed excipients

Further formulation components might also

provide performances that single components

•

be required such as wetting agents or glidants to

are uncapable to deliver. All-in-one excipients

improve the powder flow of the tableting blend.

evolutionarily developed from this concept (see

There is a huge selection of excipients available

purchasing benefits by reducing the number of vendors which reduces complexities

•

quality and regulatory benefits by minimising testing efforts and expenses, which reduces paperwork

•

warehousing benefits by minimising the number of excipients, freeing up expensive storage area

•

research and development benefits by

Table 1). By adding missing attributes, they are

simplifying formulation development and

to formulators. All these ingredients need to be

transformed to offer fully fetched formulation

shortening time-to-market, freeing up

evaluated, cleverly combined and their synergies

concepts, satisfying all the needs of an immediate

considered. The relevant ratios must also be

release target product profile.

examined to build up the required target product profile. Having such options is generally a desired feature and key for optimising formulations of demanding APIs. Though, in the field of low-tomid dose APIs, which do not require any special attention when being formulated as immediate release tablets, the situation is very different. Options ask for experience, knowledge, a huge stock of excipients, multiple trials, financial resources and substantial time investments. Time,

Formulation development is much more straight forward with Kollitab DC 87 L All-in-one components combine the

precious resources. •

production benefits by allowing for direct compression and streamlining of processes, hereby decreasing manufacturing complexity and risk of failure.

REDUCE COMPONENTS WITH KOLLITAB DC 87 L An evaluation of marketed drug products reveals that a huge variety of excipients are used in pharma manufacturing. To formulate four drug products, today’s formulation

being the most precious aspect of all, could be

functionalities required to formulate an immediate-

concepts easily require 15+ ingredients

spend in other projects.

release tablet, with the application ease of a

(four APIs and 11+ excipients). Utilising the

Consistently, formulators must balance

ready-to-use component and the robustness and

capabilities of an all-in-one component

their efforts. Time can either be invested in the

processing reliability of a customised formulation.

reduces the number of ingredients to five.

development of a standard tablet or put into challenging, yet commercially more interesting

QUARTER 1 2022 // P&C AFRICA

Is an all-in-one excipient specifically optimised to support customised formulation concepts of a

There are still four APIs, but just one excipient: Kollitab DC 87 L.

PHARMA FOCUS: TABLETING & ENCAPSULATION

Kollitab DC 87 L can substitute 11+ excipients in the warehouse and it substitutes an even larger number of

Table 1: Evolution of functionality, from co-processing to an all-in-one excipient

Product

Ludipress LCE

Ludipress

Ludiflash

Kollitab DC 87 L

Category

co-processed excipient

all-in-one excipient

Applicable dosage forms

• lozenges • chewable tablets • effervescent tablets

• immediate release tablets

• orally disintegrating tablets

• immediate release tablets

Components

• filler • binder

• filler • binder • disintegrant

• powder flow • dust free • tablet-ability • compressibility • compactability • disintegration • tablet ejection

• filler • binder • disintegrant • lubricant

Functions addressed

• powder flow • tablet-ability • compressibility • compactability

• powder flow • tablet-ability • compressibility • compactability • disintegration

• powder flow • tablet-ability • compressibility • compactability • disintegration • taste

• powder flow • dust free • tablet-ability • compressibility • compactability • disintegration • tablet ejection

excipients on the list of components screened during drug product development. Instead of testing various fillers, binders, disintegrants and lubricants, altering their ratio and still compromising on the overall performance of a physical powder blend, formulation development is much more straight forward with Kollitab DC 87 L. The only variable is the mixing ratio of the API and the all-in-one tableting aid. However, even this ratio can be predicted using ZoomLab, a virtual pharma assistant.

THE VIRTUAL PHARMA ASSISTANT ZoomLab is part of a series of BASF’s web-based assistance supporting the pharma industry with expertise. Alongside RegXcellence (providing documents and information for mainly regulatory purposes) and MyProductWorld (supporting with information on products and allowing for sample requests), ZoomLab has been tailored to simplify formulators’ lives. The algorithms and modules provided by ZoomLab range from topical

information on the chemical nature and physical

The combination of both tools provides

applications to coated oral solid dosage forms

behaviour of generic APIs. If listed, a first virtual

maximum flexibility and spontaneity, relevant

providing modified drug release, additionally

prototype of a drug product can be generated

for tender business. If an API has been

considering solubility and bioavailability of the API.

within minutes, even without having ever touched

characterised previously or is even listed among

the API.

the generic APIs in the ZoomLab database, one

ZoomLab underpins the profound formulation expertise of BASF’s application experts and is

can check a Kollitab DC 87 L based formulation

the outcome of decades of scientific formulation

A HOLISTIC APPROACH

concept even without having any of the

work. The heart of ZoomLab is a formulation

Leveraging the capabilities of ZoomLab leads to a

formulation components. If the ZoomLab check

wizard. This unique tool calculates the most

robust and reliable formulation concept without

is successful, the next simple steps are ordering

promising formulation concept based on very

the need of conducting a single trial.

the two components (API and Kollitab DC 87 L)

simple tests to characterise the API (e.g. particle

Combining the advantages of the virtual

and following the manufacturing instructions

size distribution, flowability, tablet-ability) and

pharma assistant with the performance of

provided by ZoomLab. The result is the first

some general information on its chemical nature.

Kollitab DC 87 L provides a vast set of advantages,

prototypes will be ready in no time. •

Thus, suitable excipients are selected according

resulting in a major simplification in the

to the specific needs of the API and based on

development of immediate release tablets. The

their chemical compatibility. Additionally, there

time that is liberated can be invested in more

is an API database within ZoomLab which holds

relevant projects.

YOUR VACCINE PRODUCTION PARTNER

BASF South Africa – sithembiso.dlalisa@basf.com

PHARMACEUTICAL SERVICES WE ARE SOCIAL

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Consultancy

Engineering

Construction

• Vaccine Project business plan development • GAP assessment (Process & Facilities) • New Annex 1 fully compliance (CCS, RA ...) • Feasibility Studies • QA system implementation

• Project C&Q • Cleanroom qualification (GMP & ISO 14644) • Conceptual Design • Basic & Detail Engineering

• Clean Room Systems • Biosafety Level Areas (BSL) • Freeze Dryer/Sterilization/ Depyrogenation • Integration of the filling line • Biowaste systems • Disinfection systems • Isolator / RABS integration

ANUNCI TELSTAR esp.indd 1

Commissioning & Qualification Validation • Special construction for critical environments with containment requirements • Project Management • Construction Site Supervision • Procurement • Start-up

22/04/2021 9:48:22

P&C AFRICA // QUARTER 1 2022

PHARMA FOCUS: TABLETING & ENCAPSULATION

Patient-centric 3D screen-printing technology to improve drug delivery

Evonik Venture Capital has invested in Laxxon Medical. Based in Nevada, in the US, the company has developed a 3D screen-printing technology for manufacturing structured tablets, which enable the controlled release of active pharmaceutical ingredients over time.

ITH LAXXON MEDICAL’S technology, multiple ingredients can be combined into one pill. Evonik’s specialised

polymers ensure targeted delivery of the active ingredients in these novel tablets. “This technology is great for patients. We expect fewer side effects from a more controlled drug delivery and having fewer pills reduces the risk of forgetting doses during the day,” says Bernhard

Did you know? Laxxon Medical holds the exclusive worldwide rights to the patented use and application of 3D screen-printing

technology for the development, manufacture and commercialisation of pharmaceutical dosage forms.

Mohr, head of Evonik Venture Capital. “We are pleased to support innovation that brings real benefits to people and their health.”

With Laxxon’s technology, multiple drugs can be layered on top of each other in another design, combining several pills into one

Multiple drugs can be layered on top of each other in another design, combining several pills into one.

The new technology could generate opportunities to extend patents for pharmaceutical companies because of improved drug delivery

The size, geometry, inner structure and materials

pharmaceutical companies because

Care business line. “The collaboration

Laxxon’s 3D screen printing gives the tablets

of improved drug delivery.

with Laxxon will allow us to accelerate

used are combined to allow ideal kinetics – i.e., the speed of chemical reactions in the body – for the release of active ingredients. Another benefit of the technology is the speed of printing, which is significantly faster than established 3D printing processes, allowing mass production. The new technology could generate

The size, geometry, inner structure and materials used for 3D-printed pharmaceuticals are combined to allow ideal kinetics A structured tablet with a QR code

opportunities to extend patents for

different layers. The inner structure of the pill

our activities in this important and

can, for example, have alternative layers of active

HIGH-PRECISION DRUG DELIVERY

ingredient and inert layers. This design allows for

Evonik has 60 years’ experience in developing

several doses of the drug to be released over time.

drug delivery systems. The company produces

A PERFECT PARTNERSHIP

excipients such as polymers, which serve as a

Laxxon was founded in 2017 in Switzerland

coating for tablets, for example. These coatings

by Helmut Kerschbaumer, Klaus Kuehne and

allow for the active ingredient to be released either

Achim Schneeberger. Since 2021, the company

immediately after being swallowed or after a certain

has headquarters in the US with German and

delay, or providing a sustained release over time.

Swiss subsidiaries.

Evonik’s products will be used in Laxxon’s

emerging market.”

“Evonik is the perfect partner to support

printing pastes. In addition, Evonik and Laxxon have

the development of tablets with unique release

signed a joint product development and cooperation

properties,” says Kerschbaumer, CEO of Laxxon.

agreement. Based on the agreement, Evonik intends

“We are happy to have one of the world’s leading

to manufacture tablets for Laxxon.

speciality chemicals companies with which we can

The technology is relevant to Evonik’s innovation growth fields in healthcare solutions

further develop our products and at the same time commercially manufacture them.” •

and additive manufacturing.

Evonik Venture Capital is investing in the American start-up Laxxon Medical, which has developed a 3D screen-printing technology that can be used to produce structured tablets

QUARTER 1 2022 // P&C AFRICA

“Drug delivery is becoming more high-precision and increasingly targets specific patient groups,” said Thomas Riermeier, head of Evonik’s Health

Evonik Venture Capital – venturing.evonik.com/en Laxxon – www.laxxonmedical.com

BEAUTY INNOVATIONS

100% bio-based surfactants drive the transition to renewable carbon Clariant recently unveiled its new Vita 100% bio-based surfactants and polyethylene glycols (PEGs). These beauty innovations are a means to directly address climate change by helping remove fossil carbon from the value chain.

S OUR CLIMATE gives us increasing and alarming signals of change, individuals and industries are looking for ways to reduce their environmental footprint. This is coupled with the demand for bio-based chemicals, which is set to grow in the coming years. Clariant is committed to fostering the transition to a more sustainable bioeconomy and has a growing share of bio-based products and processing aids in its portfolio. The introduction of 100% biobased surfactants and PEGs significantly expands the company’s Vita-designated ingredients. Vita products are based on renewable feedstocks and have at least a 98% Renewable Carbon Index (RCI). This is just one example of Clariant’s commitment to providing low carbon footprint solutions to customers and it’s a key milestone in Clariant’s new purpose-led strategy of accelerating sustainability-driven innovation and its vision to achieve “greater chemistry – between people and planet”. SUPPORTS SWITCH TO BIO-BASED CHEMISTRY “From the packaging to the many ingredients, a typical consumer product in coatings, personal care, home care, and industrial and agricultural applications still uses petrochemicals and therefore fossil carbon,” says Christian Vang, global head of business unit industrial and consumer specialties at Clariant. “Switching to biobased carbon chemistry remains a big challenge for manufacturers. By launching

Did you know? Because only bio-based feedstocks are used, the ingredients have a significantly lower carbon footprint than their fossilbased counterparts. The Vita surfactants are CO₂ emissions savers – they can help save up to 85% of CO₂ emissions compared to their fossil analogues.*

The range of Vita surfactants and PEGs contribute to the removal of fossil carbon from the value chain and help to save up to 85% of CO₂ emissions per tonne of product compared to their fossil counterparts

the Vita surfactant and PEG range we are offering them an important new solution to achieve this.” Designed for natural formulations with a high RCI target, the new Vita products support manufacturers in maximising the bio-based carbon content of consumer goods. Suitable applications include detergents, hair and body shampoo, paint, industrial lubricants and crop formulations. Emulsogen HCO 040 SG Vita (hydrogenated castor oil ethoxylates) is a solubiliser for active, essential and perfume oils and an O/W emulsifier for special emulsions. This product is 100% bio-based with a fully segregated supply chain and a RCI of 100%. Clariant uses 100% bio-ethanol derived from sugar cane or corn to create the ethylene oxide for its innovative new surfactants and PEGs. The bio-based material is fully segregated along the value chain from the field to the final consumer product. PARALLEL IN PERFORMANCE AND EFFICIENCY In addition to setting the standard in greener production, these new solutions are chemically equivalent to Clariant’s fossil versions, offering the same performance and efficiency to formulators and brand owners.

Customers can currently benefit from more than 70 bio-based products. This number will grow as the range is continually expanded to meet evolving market needs. During the first quarter of this year, double-digit kilotons of bio-based surfactants and PEGs will be available for global business segments from Clariant IGL Specialty Chemicals (CISC), a Clariant joint venture. As a global leader in specialty chemicals and a member of the UN Global Compact, Clariant is at the forefront of advanced carbon solutions with a unique level of expertise, know-how and industry knowledge. Click on the link – https://bit.ly/3Kskc8c – to find out more about the new Vita range of surfactants for natural formulations. • * Based on an EO estimative

Clariant – www.clariant.com

P&C AFRICA // QUARTER 1 2022

BEAUTY INNOVATIONS

Upcycling an apple a day restores skin health To achieve a circular beauty industry, any impact on the environment needs to be prevented through collaboration and transparency and by operating in harmony with nature’s rhythms. The active ingredient Pomarage was born from this intention by way of an agro-cosmetics symbiosis between Provital and Mooma. This is the story of Provital’s journey towards circular beauty and how it upcycles apple cider waste to produce the well-ageing hero ingredient, Pomarage.

REVENTION SITS RIGHT at the

ingredients, transforming the idea into

top of the waste management

a concept of “circular beauty” and working

supplier in Girona, Spain, based in close

hierarchy. The circular economy

Mooma is a family-run artisan

steadily towards a zero-waste cosmetics

proximity to Provital. With over 50 years’

stands in contrast to the linear “use-

industry that is truly in tune with

experience in the fruit-growing sector,

and-dispose” model. In this context, the

nature’s rhythms.

the company is currently operated by

cosmetics industry has a vital role to play in catalysing the bioeconomy, as it’s able to make use of and increase the value of waste – more commonly known as upcycling. Upcycled products are positioned above recycled alternatives, creating a stellar perception and the ability to obtain real gems from waste. Pomarage™ from Provital, represented

the third generation of the family, who

Beauty brands can gain value by working with suppliers and partners to set sustainable initiatives in motion

by Savannah Fine Chemicals throughout Southern Africa, is the result of recovering byproducts from apple processing in Spain. Apples are known around the world to

are dedicated to apple growing in the Empordà region. As the main byproduct of apple processing to make cider, apple pomace is agricultural waste containing a mixture of flesh, skin and seeds. As the waste product is rich in polyphenols, Provital decided to reuse it as the key raw material of Pomarage. This innovative thinking obtains a well-

COLLABORATION IS KEY IN CIRCULAR BEAUTY

ageing active ingredient that: •

To embark upon a truly circular beauty

is sourced within the immediate vicinity, i.e. 100% local in Spain

be synonymous with health. There is also

project, collaboration is crucial. Beauty

a real need for them to be upcycled, with

brands can gain value by working with

Spain alone producing more than half a

suppliers and partners to set sustainable

million tonnes of apples each year – 25% to

initiatives in motion. When it comes to

30% of which become waste material. This

conveying the message of circular beauty

•

apple waste contains a high concentration

to consumers, transparency is an essential

•

of polyphenols, which are active molecules

factor. It is vital to be completely honest

for the farming sector, thanks to

with recognised and confirmed skin

with regard to ingredient sourcing and

the processing and recycling of agri-

anti-ageing properties.1 Apples also have

traceability initiatives that demonstrate the

food waste.

known whitening properties, as well as UVB

authenticity of suppliers and raw materials.

protection and lipolytic activity. 2,3

Pomarage was born as the result of

•

is developed in line with the circular economy concept

•

has a lower environmental impact (carbon footprint) generates less waste has a positive economic impact

Provital’s intention to collaborate with

RESTORING SKIN’S HEALTHY APPEARANCE

of the circular economy to its processes,

various entities at different points in

Pomarage contributes to restoring

but also looks at the option of using

the value chain, resulting in its industrial

skin’s healthy appearance thanks to

these resources to manufacture active

symbiosis collaboration with Mooma.

its mechanism of action on reducing

Provital not only applies the concepts

QUARTER 1 2022 // P&C AFRICA

BEAUTY INNOVATIONS

inflammatory

The effects of

processes. These

Pomarage on skin health

are the markers

were further analysed

associated with cellular

is a perfect active ingredient for ethical and sustainable skin care products, designed to attract the more inclusive consumer. •

using an aged dermal

senescence, which are

fibroblast model. To this end,

addressed via multiple actions

the fibroblasts were treated with a

on the different steps of biosynthesis

dose of 0.015% of the active ingredient for

and maturation of collagen. Pomarage

24 hours. The relative gene expression

also acts on the different structures in

was then quantified using the RT-qPCR

the extracellular matrix (ECM), improving

technique, and the results were expressed

its elasticity and density in the dermis.

as a percentage of change relative to the

To understand the ingredient’s

levels found on the unstimulated control,

efficacy, Provital studied the effects of

considered as 100%. The results showed

Pomarage on the expression of certain

a higher gene expression as HAS2 and

genes involved in the structure of the ECM

COL1A2, and a lower gene expression

and therefore on skin health. To do this,

as MMP-3, demonstrating once again

normal human dermal fibroblasts (NHDF)

the positive effect of Pomarage on the

were treated with a 0.125% dose of the

structure of the skin’s ECM and on the

active ingredient for 24 hours. The relative

elasticity and density of the dermis.4, 5

quantification of gene expression was

Thanks to its well-known origin – the

performed using real-time quantitative

apple – Pomarage provides the tools to

PCR (RT-qPCR), and the results were

create a simple but effective message

expressed as a change percentage relative

that fulfils the purpose of circular beauty.

to the levels found on the unstimulated

And with its proven efficacy on improving

control, considered as 100%.

skin’s health and condition, Pomarage

References: 1.

Trullas, C., Kurdian, K., Lamy, A., Milani, M., Campos, C., Foyaca, M., & Sanz, M. T. (2015). Biorevitalising effect of a novel facial serum containing apple stem cell extract, pro-collagen lipopeptide, creatine, and urea on skin ageing signs. Journal of Cosmetic Dermatology, 15(1), 24–30. https://doi.org/10.1111/jocd.12173

Siyuan, S., Tong, L., & Liu, R. (2018). Apple phytochemicals and their health benefits. Food Science and Human Wellness, 7(3), 185–195. https://doi.org/10.1016/j. fshw.2018.09.003

Szauter, K. M., Cao, T., Boyd, C. D., & Csiszar, K. (2005). Lysyl oxidase in development, ageing and pathologies of the skin. Pathologie Biologie, 53(7), 448–456. https://doi. org/10.1016/j.patbio.2004.12.033

Lago, J. C., & Puzzi, M. B. (2019). The effect of aging in primary human dermal fibroblasts. PLoS ONE, 14(7), 1–14. https://doi.org/10.1371/journal.pone.0219165

Tzellos, T. G., Klagas, I., Vahtsevanos, K., Triaridis, S., Printza, A., Kyrgidis, A., Karakiulakis, G., Zouboulis, C. C., & Papakonstantinou, E. (2009). Extrinsic ageing in the human skin is associated with alterations in the expression of hyaluronic acid and its metabolising enzymes. Experimental Dermatology, 18(12), 1028–1035. https://doi.org/10.1111/j.1600-0625.2009.00889.x

Provital – www.weareprovital.com/en Savannah Fine Chemicals – www.savannah.co.za

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www.savannah.co.za P&C AFRICA // QUARTER 1 2022

BEAUTY INNOVATIONS

The inverse emulsion: a cost-effective hero formulation technology For the longest time, w/o emulsions were reserved for use in sunscreens, waterproof makeup and nappy (barrier) creams. Yet over the years, emulsion technology has evolved widening the range of applications for emulsions to almost all personal care products. AECI Specialty Chemicals explains the history behind the technology and how the application focus has changed.

difference between water-in-oil (w/o)

SELECTING W/O EMULSIONS AND EMOLLIENTS

phase content increases the viscosity of the

and oil-in-water (o/w) emulsions. Water

T’S IMPORTANT TO understand the main

In w/o emulsions, increasing the dispersed

In the past, w/o emulsions were perceived

final emulsion. Thus, oil phases in the order

and oil are not miscible with each other, so

as sticky, greasy, heavy, hard to stabilise

of 10% to 15% yield thick creams, while oil

emulsifiers are needed to mix the two parts

and expensive. Yet scientific advances have

phases in the range of 18% to 35% yield lower

and create a stable end-product.

addressed and counteracted these issues

viscosity lotions.

In colloidal science, the ‘inside’ phase is called the dispersed phase while the ‘outside’ phase is referred to as the continuous phase. In a w/o emulsion, the water is the dispersed phase and the oil, the continuous phase. W/o offers a number of practical advantages, because the oil is on the “outside”. For example, the

over time. It is now possible to easily produce

The choice of emollient is critical to the sensory experience of a final product

end-product feels oily to the touch – this

The other advantage of w/o is that the viscosity of the oil phase is proportional to the final emulsion viscosity, due to the oil phase being the continuous phase. This means that adding cosmetic waxes, butters and even petrolatum, will significantly alter the structure of the emulsion, allowing applications like beauty balms and body butters. The choice of emollient is critical to the

is commonly experienced with sunscreens.

w/o emulsions that are cost-effective, easy to

sensory experience of a final product. Selecting

The characteristic enables water resistance,

stabilise, fast absorbing, feel light on skin (where

more volatile emollients with high spreading

which is why w/o is the preferred emulsion

required), and are non-tacky. These factors

coefficients, such as silicones, squalanes and

type for sunscreens, waterproof makeup and

are addressed by two main components of the

certain alkanes, achieves light emulsions that

barrier creams.

formulation, being the choice of emulsifier and

penetrate the skin easily.

The lipid barrier also locks in moisture, so w/o emulsions are great for problematic

the selection of emollients. AECI Specialty Chemicals has a solution for

Similarly, when more occlusive emollients are used, like mineral oil and certain vegetable

skin, prone to psoriasis, eczema and

both of these ingredient types. Its easy-to-use

oils, heavier emulsions are created. A heavier

dryness. This begs the question, why are the

w/o emulsifier base is supplied in a viscous liquid

emulsion performs better at preventing

majority of personal care creams o/w, which

format and is used at very low dosages between

transepidermal water loss, effectively

is the opposite type of emulsion?

1.8% and 3%.

increasing moisturisation.

QUARTER 1 2022 // P&C AFRICA

BEAUTY INNOVATIONS

METHOD OF MANUFACTURE:

1. In separate vessel add phase A ingredients in the correct order and mix after addition at a temperature of 70°C. 2. Add phase B to mixing vessel and heat to between 75°C and 80°C. 3. Under high shear add 30% of phase A to phase B. 4. Ensure emulsion inversion occurs. 5. Add the balance of phase A and continue to homogenise until a thick lotion is formed. 6. Ensure that phase A is completely emulsified. 7. Cool to below 55°C and add fragrance. 8. Homogenise once more.

Table 1: Cost-effective tissue oil lotion

Phase

Mass %

Approx. material cost per kg

In-formulation cost per kg

77.4

Salt (Sodium Chloride)

2.0

$0.33

$0.01

Glycerine

2.0

$1.84

$0.04

White Oil

16.0

$1.32

$0.21

W/O Emulsifier Base 3

1.3

$13.16

$0.17

Preservative PE91

0.8

$9.21

$0.07

Fragrance

0.5

$29.61

$0.15

Step

Ingredient

Deionised Water

Total: $0.65/kg

EQUALLY BENEFICIAL FOR HAIR CARE Of course, the technology is not limited to skin care. Because these emulsions can be designed with such large quantities of oil, it also makes them perfect for certain hair care products such as oil moisturisers, masks, hair foods and serums. Imagine combining a blend of nourishing oils that are highly favoured by consumers, such as argan oil, coconut oil, Abyssinian oil and sapote oil, and saving costs in the process. The cost savings are made possible by the emulsifier, which allows for water to be included in the formulation without hampering the performance of the oils. Table 1 features an example of a formulation for a highly cost-effective tissue oil lotion. The formulation uses minimal ingredients and yet it yields a beautifully glossy, rich cream that radiantly moisturises the skin. •

Imagine combining a blend of nourishing oils that are highly favoured by consumers, such as argan oil, coconut oil, Abyssinian oil and sapote oil, and saving costs in the process

AECI Specialty Chemicals – thureya.sarlie@aeciworld.com

Contact our experts for the perfect emulsiﬁer

- Water-in-Oil - Oil-in-Water - Cold Process (polymeric) - Natural - Wax Concentrates Thureya Sarlie (Commercial) E-mail thureya.sarlie@aeciworld.com

P&C AFRICA // QUARTER 1 2022

FRAGRANCES

Feel the world by harnessing the power of sensual fragrance experiences Souvenirs can narrate stories from the past or conjure up visions of the future. Düllberg Konzentra’s new trend concept aims to do both simultaneously. “Feel the World” sparks sensual mind movies for those who feel the lure of far-away places – even when travel is restricted. Experts of the international fragrance house reveals how in this article.

HAT ARE THE things we cannot and do not want to relinquish in life? What is close to our hearts? Sometimes these can be ordinary, everyday objects, like souvenirs that remind us of discoveries of foreign places and the world around us. For Lisa-Marie Achilles of the marketing team at Düllberg Konzentra, this idea was

to different destinations and to create new memories. With Feel the World, we want to re-open the doors to the world and make this possible. We have created sensual fragrance experiences which invoke new fragrance memories from around the world,” she explains.

the inspiration for a new fragrance concept designed for use in body care products. “Over the past two years, we have become accustomed to living with memories and souvenirs of more care-free times. Now the time has come to head out once again

consumer insights, explains Christian Lüke of Düllberg Konzentra’s marketing team. One of these insights is slow luxury. “Instant gratification is passé; now the journey is very much the reward. Progressing slowly along the path of discovery, rather

THREE TOPICS UNITED IN ONE CONCEPT Feel the World is based on a variety of

Tel 011 608 4944 Fax 011 608 4948 Email sales@sensetek.biz

Sensetek.indd 1

QUARTER 1 2022 // P&C AFRICA

2017/03/02 11:50 AM

FRAGRANCES

than focusing exclusively on the end result, is a source of pure joy. This is all about those moments of reflection that consumers want to savour,” he comments. The concept goes hand in hand with a longing for the unusual and exotic. The different traditions and backgrounds of ideas and objects encourage us to discover and explore the stories behind them. Ultimately, it’s about that all-encompassing topic of inspiration – and a modern interpretation of exciting products from around the world.

We have created sensual fragrance experiences which invoke new fragrance memories from around the world Achilles adds: “With Feel the World we want to send consumers on a sensual journey around the world – and to enable customers to create inspiring body care products that they can further underpin with ‘souvenirs’.” This serves to create a sensual museum of memories where every object tells its own distinctive story.

Concepts from various continents AMERICA: A TRIBUTE TO THE SWEAT LODGE Dancing Around Glowing Stones is the story that has America as its destination. It references the sweat lodge tradition of the indigenous peoples of America; these sacred places were used for spiritual cleansing and purification ceremonies. “Fragrances played a key role, for example sage or pine. The sweat lodge ceremony aimed to facilitate a rebirth experience, to rebalance

disrupted energy and to liberate from illness, pain and mental burdens,” says Lüke. As a bath or shower steamer for a fragrant, cleansing bath at home, this story can be reinterpreted – and illustrated with pine firewood as a souvenir. The main notes in the fragrance are aromatic fougère with pine and sage, with drifts of mandarin, tonka and vanilla floating in the background. EUROPA: CELEBRATING SAVON DE MARSEILLE Soap from Marseille is famous across Europe. The recipe itself hasn’t changed in over a century; it is based on pure, natural ingredients – and is also the perfect souvenir. This iconic product could be reborn as a “Marseille Soap” shower bar with richly nurturing ingredients such as olive, herbs and sea salt – and rounded off with two fragrances by Düllberg Konzentra: a floral-green creation with fresh notes and violet petals combined with olive, almond, tonka, vanilla and woody undertones; and a variant with honeysuckle, rose, lilac and balsamic notes. ASIA: THE POWER OF WATER Asia is represented in a journey to Bali by the authentic Melucat ritual that cleanses the body, mind and soul. The focus is on water, and the Balinese people use this ritual to symbolically enter a new phase of life, to recover from an illness or to cleanse themselves of elements that disrupt the soul’s balance. “Our care concept integrates sea minerals, salt and a touch of frangipani. As a solid shower bar in the shape of a frangipani blossom, it becomes a beautifully fragrant souvenir,” says Achilles. Düllberg Konzentra has developed two scents for this theme: a citrusy, floral-fruity composition with citrus, frangipani, coconut and

pineapple; and a floral-aromatic composition with citrus, complemented by sage, aquatic notes and patchouli. OCEANIA: AUSTRALIAN SECRETS Australia is home to numerous plants and bushes that play an important role in the culture of the Aboriginal people. Evergreen lemon myrtle, the pods of the acacia and the fruits and leaves of the papaya tree are all used in traditional medicine. Düllberg Konzentra has translated these ingredients into an appealing, modern body care concept. Achilles says: “As an immune-systemboosting shower product with lemon myrtle, acacia and papaya, this pays tribute to the ancient culture of Down Under. Our fruity-green fragrance with passionfruit, orange, mango and vanilla beautifully expresses the concept.” AFRICA: THE MYSTIC POWER OF BLACK SOAP People in West Africa have been making their own soap for centuries. The legendary black soap “Dudu Osun” is crafted with palm kernel oil and shea butter, the ash of cocoa pods and dried palm bunch ash, with added citrus extract, wild honey and aloe vera. This traditional recipe can be given a new lease on life in the form of a shower bar. It combines the natural caring ingredients of black soap with the added benefits of wild honey, aloe vera and shea butter, which in turn is extracted from African shea nuts, the “souvenir” of this care concept. The perfumers at Düllberg Konzentra have used gourmand and floral notes – including honey and peach, orris, clove and milk – in their composition of this product. • Düllberg Konzentra – www.duellberg-konzentra.de/en

Fragrances are t he

feelings of flowers. www.duellberg-konzentra.de

P&C AFRICA // QUARTER 1 2022

PACKAGING

Improve coding and marking while reducing your impact on the environment Climate change and the need to reduce carbon emissions have become global priorities today. With the declaration of climate emergencies by governments at all levels, companies are striving to find ways to contribute, either by reducing their emissions or supplying goods and services to enable others to do so. TracePack’s coding and marking lasers are designed to have minimal impact on the environment and to be energy efficient.

HE USE OF LASER technology positively impacts the environment because no waste is produced, therefore

eliminating the need to recycle potentially harmful residual products. To apply codes, TracePack recommends solutions based on laser technology due to its ability to mark a wide range of materials such as plastics, cardboard, glass etc., cleanly and safely, with great legibility, permanence and low maintenance costs.

With vision systems, the manufacturer can ensure that production processes are fault-free

Did you know? TracePack’s In-Sight 2D machine-vision systems are unmatched in their ability to inspect, identify and guide parts. These self-contained, industrial-grade vision systems combine a library of advanced vision tools with high-speed image acquisition and processing. A wide range of models, including line scan and colour systems, meet most price and performance requirements.

and firmly sealed. Even though materials of high quality are used, contamination by small dirt particles can still occur, tubes may become deformed when the outer packaging is applied, or there may be faulty seals at the base of the tube. With vision systems, the manufacturer can ensure that production processes are faultfree. The cameras detect foreign bodies based on the contrast to their surroundings. A red, ring-shaped LED light illuminates the inside of the tube from above. Any undesired particles cast a shadow detected by the TracePack cameras, making it possible to see objects of

system could not completely guarantee that

the same colour as the tube itself.

particles of dirt from the preliminary tube production stage would not be inside the tube

SEAMLESS CHECKING PROCEDURE

after the filling and sealing process.

The high-performance technology from

During the filling process, In-Sight vision systems check that the tubes are round, clean

TracePack ensures that the nozzles enter the tubes accurately to within a tolerance of 3mm.

The most appropriate technology for marking and coding on each container depends on the characteristics of the container, whether it is a jar of cream, deodorant, aluminium aerosol can, makeup and perfumes or colognes. The iCON-3 meets the high quality standards of the pharmaceutical industry for the coding of labels, tubes and boxes and ensures perfect coding for personal care products. Whatever the material used, TracePack’s laser coding solutions will guarantee clear, permanent and secure marking of batch numbers as well as QR codes.

COMPLETE PACKAGING INSPECTION FOR TUBES A recent development in manufacturing, vision systems are used to check whether the actual product packaging is clean and safe before tubes are filled. Previously, filling systems that were not equipped with a machine-vision

QUARTER 1 2022 // P&C AFRICA

Inspection of tubes on a production line

PACKAGING

Coding on mascara packaging the faulty tube is ejected from the process. The In-Sight vision systems are networked to a central panel PC , which records images of all

Laser markings on tube packaging

the defective pieces. This makes it possible to detect faults quickly without having to recheck

The checking procedure takes place without an

outside of the tolerance range, it is identified as

the actual packaging item that has already been

additional operation step during the process.

faulty and is not filled.

ejected from the process. •

The individual cameras receive a trigger for

The cameras also check the seal itself. If

every tube and record pictures of the packages

the seal is not complete or the printing is not

as they move past. If a tube is out-of-round or

properly aligned with the specified parameters,

TracePack – www.tracepack.co.za

Improve your company coding and marking while reducing the impact on the environment. With the declaration of climate emergencies by governments at all levels, companies are striving to find ways to contribute. Our coding and marking lasers are designed to have minimal impact on the environment and be energy efficient. The use of laser technology also positively impacts the environment because no waste is produced, therefore eliminating the need to recycle potentially harmful residual products.

Reach out and let us introduce you to our comprehensive packaging solutions today. +27 10 020 7221

www.tracepack.co.za

P&C AFRICA // QUARTER 1 2022

PACKAGING

Overcoming challenges in sustainable packaging manufacturing Sustainability in the packaging industry is one of the key aspects in fighting the plastic waste issue and ultimately climate change. The challenges that this presents, require flexible and powerful automation technology to be overcome.

F MORE SUSTAINABLE materials are used in

sensor technology. This solution can be placed

Omron supports accurate detection of glue

packaging, it is still of the highest importance to

closer to the sealing bar.

patterns. The high resolution and brightness

ensure the quality of the end product remains

3. Packaging and label quality control

settings allow low-contrast defects to be detected, even in the toughest light conditions

unaffected. Changing to more sustainable materials

Flexible packaging with new elements such as

can result in typical problems on a manufacturing

resealable closures place different demands on

line. To overcome these challenges, automation

packaging integrity and quality testing. Thinner

and robotics technology that works flexibly with

films, bio-based materials, or those with a

Cardboard boxes made of recycled fibres have

different materials is needed.

higher recycled content have a different thermal,

higher porosity and are more flexible.

1. Film jamming

elongation and puncture resistance profile.

Although thinner, recycled films are more

These differences can lead to irregularities in

sustainable, they can tangle quicker. Correct handling with maximum throughput and minimum film consumption is key to overall original equipment effectiveness. Omron’s film tension control system provides synchronised control of tension, feed and cut. This is complemented by (colour) mark detection for film compensation through motion control to

the shape and edges during forming and cutting.

Changing to more sustainable materials can result in typical problems on a manufacturing line

or with difficult to detect materials. 5. Multi-material handling

Traditional palletising solutions are complicated to adapt and program, they take up a lot of space, and cannot be relocated to other parts of the plant when needed. It is therefore advisable to have an integrated collaborative robot (Cobot) solution with dedicated grippers to safely handle a wide range of irregular shapes, porosity levels and delicate objects.

ensure optimal unwinding of the roll. The Omron

Challenges in reading, checking, or verifying label

INTEGRATED AUTOMATION PLATFORM

Packaging Library offers a wide range of function

information on packaging are overcome with

Sysmac from Omron is an integrated automation

blocks for film processing in VFFS machines.

Omron’s high-speed inspection system.

platform that provides complete control and

The system is suitable for multiple lines and

2. Film sealing

management of an auotmated plant.

Thinner film materials offer lower costs and

transparent integration with robotic systems.

improved aesthetics. However, these materials

It offers a multi-camera platform with a single

controller series supports synchronous control of all

are more sensitive to heat when using traditional

controller for multiple-image capture at high

machine devices and offers advanced features such

adhesives and sealing technologies.

speed to reliably detect potential defects.

as motion, robotics, and database connectivity.

The sealing temperature must be controlled

4. New adhesives and gluing techniques

At the core of this platform, the machine

This multidisciplinary concept allows to simplify the

and automatically adjusted to avoid losing

To produce and seal cartons, companies are

solution architecture, reduce programming effort

productivity or sealing defects.

increasingly relying on a strategic and reduced

and optimise productivity. •

Omron addresses this challenge with an

application of adhesives. This requires a high

AI-based temperature control algorithm

level of precision and continuous quality control.

synchronised with machine movement and

With its automated visual inspection system,

Omron – www.industrial.omron.co.za

Flexible Production Integrated Robotic Solutions

• Autonomous teach and go and self-recharging • Automated can fit within a line or factory to achieve end to end automation and traceability • Intelligent can optimize travelling path and work within a fleet of up to 100 robots • Safe fully collaborative and operate along people Would you like to know more? +27 (0)11 579 2600 info_sa@omron.com industrial.omron.co.za

flexible_production_177x65mm_ad_enza_01_d02.indd 1

QUARTER 1 2022 // P&C AFRICA

07-09-21 13:57

A full-service experience

Review Ishida Europe has extended its range of QX Flex tray sealers with the launch of a new model, which meets market demands for a compact, high-performance solution. The innovative model also maximises output, capacity and flexibility for medium- to high-volume production lines. Sustainability is an integral part of Multivac’s strategy. For 60 years, the company’s packaging solutions have ensured that sensitive products globally can be processed efficiently, as well as being packed hygienically, reliably and attractively.

Rotolabel is passionate about the environment and focuses on minimising any negative ecological impact of its products. The company subscribes to the four Rs of packaging sustainability: responsible sourcing; reduction of materials; recyclability and increased recycled content

Read more in the latest issue of Packaging Review Out Now! ADVERTISING

Interested in advertising in PACKAGING REVIEW? If you are a supplier to the packaging industry, this will be an ideal opportunity to showcase your product offering and create additional brand awareness within the food, beverage, pharmaceutical, cosmetics, personal care, and home care manufacturing sectors.

Contact our advertising sales executives to book your space: Anita Raath Sales executive +27 (0)82 976 6541

Carla Melless Sales executive +27 (0)83 260 6060

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Pharmaceutical & Cosmetic Review Africa Q1 2022

Articles inside

Overcoming challenges in sustainable packaging manufacturing

Improve coding and marking while reducing your impact on the environment

Feel the world by harnessing the power of sensual fragrance experiences

Upcycling an apple a day restores skin health

Kollitab DC 87 L – the all-in-one tableting solution

Curl care – addressing the challenge for formulators

Innovative hair care that celebrates individuality