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I take the privilege to present the hard copy compilation for the [Volume 3 Issue (1)] of Journal of AYUSH:-Ayurveda, Yoga,Unani ,Siddha and Homeopathy. The intension of JoAYUSH is to create an atmosphere that stimulates creativeness, research and growth in the area of Ayurveda, Yoga, Unani, Siddha and Homeopathy. The development and growth of the mankind is the consequence of brilliant Research done by eminent Scientists and Engineers in every field. JoAYUSH provides an outlet for Research findings and reviews in areas of Ayurveda, Yoga, Unani, Siddha and Homeopathy found to be relevant for National and International recent developments & research initiative. The aim and scope of the Journal is to provide an academic medium and an important reference for the advancement and dissemination of Research results that support high level learning, teaching and research in the domain of Ayurveda, Yoga, Unani, Siddha and Homeopathy. Finally, I express my sincere gratitude and thanks to our Editorial/ Reviewer board and Authors for their continued support and invaluable contributions and suggestions in the form of authoring writeups/ reviewing and providing constructive comments for the advancement of the journals. With regards to their due continuous support and co-operation, we have been able to publish quality Research/Reviews findings for our customers base. I hope you will enjoy reading this issue and we welcome your feedback on any aspect of the Journal.

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Journal of AYUSH : Ayurveda, Yoga, Unani, Siddha and Homeopathy

Contents

1. Observational Study on the Role of Gandusha (Jambu Patra Kwatha) in the Management of Mukhapaka Rakesh Shukla, Amit A Patil, Vidula A Patil

2. Concept of Avartana in Ayurvedic Classics Nagasri N. Ekbote, Rajshekhar V. S., Sreelakshmi C. Reddy, Nitin B. Patil

3. Concept of Kshudraroga in Brihattrayi and Laghuttrayi Rakesh Shukla, Ajit S Verma

4. Conceptual Study of Kamala Harkrishna BN, Yadav Chhaju Ram

5. Doctrine of Signature - A key in Discovering the Therapeutical Effect of Zornia gibbosa Span Bipin Vithal Sawant

6. A Practical Approach to Clinical Trials: Concepts and Methodologies Qamar Uddin, L. Samiulla, Syed Shakir Jamil

7. Antimicrobial Activity of Indian Vessels (Copper, Silver and Bronze): A New Horizon Megha T, Rekha CR, Sreevastha

8. Preparation and Physico-chemical Analysis of Apasmarari Rasa â&#x20AC;&#x201C; An Ayurvedic Formulation Vikas Saroch, R. S. Hiremath

9. A Critical Appraisal of Bhagna (Fracture) and Its Management in Ancient Indian Surgery P. L. Rasale, S. Y. Raut, U. S.Namburi, M. N. Suryawanshi

10. A Study on Promoting Physiological Personalities of the Students by Vethathiri Maharishi's Nine-Center Meditation Using Quantum Magnetic Resonance Analyzer Raj Kumar, G. R. Valliammal

11. Bhojanottara Karma â&#x20AC;&#x201C; An Accentuated Ritual after Intake of Ahar Kasha Nath Samagandi, Jagriti Sharma Samagandi, Kamalesh Kumar Sharma

Journal of AYUSH : Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Observational Study on the Role of Gandusha (Jambu Patra Kwatha) in the Management of Mukhapaka Rakesh Shukla1*, Amit A Patil2, Vidula A Patil3 Department of Swasthavritta, Sriganganagar College of Ayurvedic Science and Research, Sri Ganganagar, Rajasthan, India 2 Department of Swasthavritta, MES Ayurvedic college, Chiplun, Maharastra 3 NIA, Jaipur

Abstract Mukhapaka is neither a serious disorder nor one that can be dismissed as cursory. It is not life-threatening, but at the same time it can be crippling by grossly disturbing the individualâ&#x20AC;&#x2122;s life style. Habits like tobacco chewing, smoking, etc., have increased incidences of diseases pertaining to oral cavity. To assess the role of Jambu Patra Kwatha Gandusha, as Upakrama in the management of Mukhapaka. Gandusha of Jambu Patra Kwatha which have Kashaya, Madhur and Amla Rasa, Shita Virya and other properties like Pittaghnata, Vranaghnata and Varna Ropan. On the basis of this study, it can be concluded in a nutshell that Gandusha with Jambu Patra Kwatha provided significant result in reducing signs and symptoms; and also in preventing recurrent Mukhapaka.

Keywords: Gandusha, jambu, mukhapaka

Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Concept of Avartana in Ayurvedic Classics Nagasri N. Ekbote1*, Rajshekhar V. S.1, Sreelakshmi C. Reddy1, Nitin B. Patil2 Department of Panchakarma, KLEU’S Shri BMK Ayurved College and Research Centre, Belgaum, India 2 Department of Agada Tantra, KLEU’S Shri BMK Ayurved College and Research Centre, Belgaum, India 1

Abstract There are many drug doses forms for drug delivery systems available in Ayurvedic classics. Snehapaka is one among these pharmaceutical processes. It is a method of preparation of medicated sneha (ghee or oil) and depending on stage of preparation, it is of three types. Among these, the madhyama paka sneha is used to administer orally. When this snehapaka is done repeatedly with drava dravya (decoction, milk, etc.) and kalka (paste) the process is called Avartana. Depending on the number of processes, the formulations are named shatapaki and sahsrapaki. This avartana process was generated to potentiate the formulation which was used from Samhita period to minimize dose, for easy consumption and assimilation of the medicine. This article aims to review a unique method of sneha preparation (avartana) in different contexts of Ayurveda.

Keywords: Snehapaka, avartana, shatapaki, sahasrapaki

Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Concept of Kshudraroga in Brihattrayi and Laghuttrayi Rakesh Shukla1*, Ajit S Verma2 1

Department of Swasthavritta, Sriganganagar College of Ayurvedic Science and Research, Sriganganagar, Rajasthan, India 2 Department of Samhita, Uttranchal Ayurvedic Medical College, Dehradun, India

Abstract Changes in lifestyle like excess pollution, use of synthetic chemicals, and also improper diet due to hectic schedule have increased number of patients with diseases like Khalitya and Palitya. In todayâ&#x20AC;&#x2122;s sophisticated society, external features like hair and skin decide the status of the person and make one more conscious about them. Nowadays, occurrence of a few Kshudrarogas is very high in the society. Their prevalence is experienced everywhere and they cannot be considered as minor in nature and neglected. There is confusion in the Kshudraroga, its number, its definition, its factors like severity of Hetu, Lakshana and Chikitsa. The aim of this paper is to study and classify Kshudraroga from Brihattrayi and Laghuttrayi. Kshudrarogas do not have Doshaja classification (lacking Sankhya Samprapti). They have Hetus and Lakshanas of lower magnitude. Almost all texts of different chronological order have described Kshudraroga with less or more elaboration.

Keywords: Kshudraroga, hetu, lakshana, chikitsa

Journal of AYUSH : Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Conceptual Study of Kamala Harkrishna BN*, Yadav Chhaju Ram Department of Kriya Shareera, National Institute of Ayurveda, Jaipur, India

Abstract In the present world, major group of diseases called lifestyle diseases are sprouting and growing like mushroom. Too many people are dying relatively young from these lifestyle related diseases. Among these disorders, a group of liver diseases is one of the major fast growing groups of diseases. Main reason for this is the insult that we show in the form of improper life style to our liver, which is the major metabolic organ in the body. Jaundice is the major sign that we come across in many of the liver diseases. Ayurveda also speaks about this under the heading of Kamala. Kamala is a disease entity which occurs primarily due to vitiated Pitta Dosa. It is also a Raktaja Vikara. Kosta Shakashrita and Shakashrita are the major two types of Kamala among different types of Kamalas mentioned in the classics. Kamala includes a spectrum of liver diseases that we come across in contemporary medical science. Before blindly prescribing the readymade medicines it is very important to understand the pathology of that disease. Once this is done it is easy to get into treatment aspect.

Keywords: Kamala, liver diseases, pitta dosa, lifestyle diseases

Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Doctrine of Signature - A key in Discovering the Therapeutical Effect of Zornia gibbosa Span Bipin Vithal Sawant* Department of Dravyaguna, G. J. Patel Institute of Ayurvedic Studies & Research,Gujrat, India

Abstract According to Doctrine of signatures the herbs that resemble various parts of the body can be used to treat ailments of that part of the body. The theme of natural objects' shapes having significance is very old and can be correlated with “Purushoayam Lokasammitah” (man is epitome of universe) of Ayurveda. In Shatpat Bhrahman, a reference regarding functional correlation of various parts of the trees to that of human organ also supports the above philosophy. Inspired by this, folklore practitioner of Udupi district of Karnataka has made a successful effort to utilize a commonly available drugs Zornia gibbosa in the treatment of fracture by analysing its characteristic sticky nature which help the leaves to unite ones they are cut. To substantiate the folklore claims animal experimentation was carried out which showed significant anti-inflammatory and analgesic activity. This signifies Doctrine of signatures can be effectively utilised as a primary or firsthand tool in the direction towards the analysis of therapeutic effects of any unexplored herb as in case of Zornia gibbosa Span

Keywords: Zornia gibbosa Span., doctrine of signatures, purushoayam lokasammitah (man is epitome of universe)

Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

A Practical Approach to Clinical Trials: Concepts and Methodologies Qamar Uddin1*, L. Samiulla1, Syed Shakir Jamil2 1

Regional Research Institute of Unani Medicine (RRIUM), Bhadrak, Odisha, India Central Council for Research in Unani Medicine (CCRUM), Janakpuri, New Delhi, India

Abstract Clinical trial is a research study that is conducted on human volunteers to collect safety and efficacy data for health interventions (e.g., drugs, diagnostics, devices, therapy protocols). Clinical trial is intended to produce knowledge valuable for understanding human disease, preventing and treating illness and promoting health. Clinical trials can only be conducted after gathering satisfactory information on the quality and nonclinical safety of the product, and after taking Ethics Committee approval. Initially, these trials are conducted on small number of subjects. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multi-center trials in multiple countries. Clinical trials are used to test the safety and efficacy of new drugs and therapies on human volunteers. Today, such investigations are carried out using protocols that adhere to accepted standards of safety, patient care and data interpretation. However, history shows that patient welfare was not always such a high priority. Recently, clinical trials are facing several challenges, such as imperfect public understanding of clinical research, lack of interest in practitioners, and poor coordination between health management organizations and academic medical centers. So, there is a need to educate all practitioners about clinical research, and to stimulate their interest in clinical research careers. The aim of this review is to enlighten general public and practitioners about the facts and general details of clinical trials.

Keywords: Clinical trial, protocol, health, safety, efficacy

Journal of AYUSH : Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Antimicrobial Activity of Indian Vessels (Copper, Silver and Bronze): A New Horizon Megha T1*, Rekha CR2, Sreevastha3 Govt. Ayurveda Medical College, Mysore, Karnataka, India 2 Maharani’s Science College for Women, Mysore, Karnataka, India 3 Govt. Ayurveda Medical College, Mysore, Karnataka, India 1

Abstract Water is the essence of life. Water known as Jala in Sanskrit has several synonyms in Sanskrit. One of the synonyms of water in Sanskrit is Jeevanam which means life. Water is not only an essential element but is also one of the five basic essential elements for the creation of this universe (including the humans). It is the Jala Mahabhoota – the water element. Charaka Samhita mentions that all types of fluids in the body are made up of Jala Mahabhoota (water element). Hence, the water we use is of life-giving principle and a detailed knowledge of water, its purity and purification is very important. Hence, in this study an attempt was made to check the efficacy of Indian vessels in purifying water. The study revealed that copper, bronze, silver and steel were capable of purifying water in respective order.

Keywords: MPN (multiple-tube fermentation) test, copper, silver, bronze, water (jala), SSLB (single-strength lactose broth media), DSLB (double-strength lactose broth media)

Journal of AYUSH : Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 4, Issue 1 www.stmjournals.com

Preparation and Physico-chemical Analysis of Apasmarari Rasa – An Ayurvedic Formulation Vikas Saroch*, R. S. Hiremath Department of Rasashastra, KLEU’s Shri B. M. K. Ayurveda Mahavidyalaya, Belgaum-03, Karnataka, India

Abstract Apasmarari Rasa, a unique Ayurvedic preparation has the main ingredients like Hingulottha Shuddha Parad (HSP), Shuddha Gandhaka (SG) and Shuddha Tuttha (ST) and Bhavana Dravya (trituration) as Tinospora cordifolia (Guduchi). The Chakrikas (pellets) prepared after giving bhavana to the above-mentioned ingredients, were sealed in Sharava (shallow earthen disc) Samputa (uniform smeared and dried) and subjected to Agni. After self-cooling (Swangasheeta), the mixture was triturated with Musa paradisiaca Linn (Kadali Kanda Swarasa) tuber juice for one day and the final product was subjected to analysis. Physico-chemical analytical findings were as these: Grahya Hingula showed 35.6% of Hg, Grahya Gandhaka showed 91.9% of S, and Grahya Tuttha showed 23.84 % of copper. Hingulottha Shuddha Parada (HSP) showed 99.39% of mercury (Hg), Shuddha Gandhaka (SG) showed 87% of sulfur (S) and ST showed 19.12% of copper (Cu). Prepared Apasmarari Rasa (ARR) showed 18.57% of Hg, 8.85 % of sulfur (S) and 15.26% of copper (Cu).

Keywords: Agnisamskara, apasmarari rasa, gandhaka , mardana ,parada, tuttha.

Journal of AYUSH : Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

A Critical Appraisal of Bhagna (Fracture) and Its Management in Ancient Indian Surgery P. L. Rasale1*, S. Y. Raut2, U. S.Namburi3, M. N. Suryawanshi3 1

Govt. Ayurved College, Nagpur, India Shalyatantra Department Government Ayurved College, Nagpur, India 3 Ayurved Mental Health Research Institute, CCRAS, Nagpur, India

Abstract Fractures are one of the common surgical conditions in the orthopedics and many of the new techniques are developed for the management as per the condition. In ancient Indian surgery Acharya Sushruta described extensively in Sushrutasamhita Nidana and Chikitstastans about fracture, its etiology, classifications and various modalities of management and also termed this condition as Bhagna. In ancient times, Bhagnas were commonly seen in wars or violent attacks by wild animals, etc., but presently these are common due to road traffic accidents. In the classics of Ayurveda the classification of Bhagna was extensively explained based on nature of violence, shape of fracture, displacement of fracture fragments, fracture with or without wound. Further Sushruta explains that if it occurs in the bones it is called as Kandabhagna (bone fracture) and in the joints it is called as Sandhimukta (joint dislocation). Again he sub-classifies Kandabhagna under twelve types and Sandhimukta under six types. Sushruta describes various modalities of fracture management; as per the condition he suggests the conservative or surgical management. Conservative management includes Kushabandhana, Alepa, Chakrayog, Tailadroni, etc. This paper elaborates the wisdom of orthopedic branch in ancient times especially fracture and its management with possible modern co-relates and shows how much knowledge existed and how well organized it was so many centuries ago. The concepts, theories, and techniques practiced several thousand years ago hold true even in todayâ&#x20AC;&#x2122;s practice.

Keywords: Kandbhagna, fracture, ancient Bhagna surgery, asthibhagna

Journal of AYUSH : Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 4, Issue 1 www.stmjournals.com

A Study on Promoting Physiological Personalities of the Students by Vethathiri Maharishiâ&#x20AC;&#x2122;s Nine-Center Meditation Using Quantum Magnetic Resonance Analyzer Raj Kumar1*, G. R. Valliammal2 Yoga for Human Excellence, Bharathiar University, India

Abstract The nine-center meditation of simplified Kundalini yoga was formulated by sage Vethathiri Maharishi. It involves the following centers: Mooladhara, Swadhistana, Manipuraga, Anahatha, Visuddhi, Agna, Thuriya, Shakthi Kalam and Shiva Kalam. Meditation is done on all the nine centers, seven of which are endocrine glands located within the physical body and Shakthi Kalam, Shiva Kalam are universal field and absolute space respectively. Meditation commences at Mooladhara Chakra, followed by meditation on each of other Chakras and concludes when the mind merges with absolute space. The quantum magnetic resonance analyzer is a scanning machine working on the basis of electromagnetic waves of body cells. The weak magnetic frequency and energy of human body is collected by holding the sensor. After amplification by the instrument and processing by the built-in microprocessor, the data are compared with the standard quantum resonant spectrum of diseases, nutrition and other indicators incorporated in the instrument. Finally, it generates reports on 22 health parameters. To prove the research concept, students of two different schools pursuing 11th standard were selected and chosen â&#x20AC;&#x201C; one as experimental group and the other as controlled group. After six months of regular practice of the nine-center meditation, the former group of students progressed well compared to the later in the following: considerable increase in hormone secretions of endocrine glands, insulin in blood and BMI and significant decrease in pulse rate, blood pressure and blood sugar level. The nine-center meditation regulates and promotes the secretions of hormones which uplift physiological functions of humans.

Keywords: Mooladhara, swadhistana, manipuraga, anahatha, visudhi, agna, thuriya, shakthi kalam, shiva kalam

Journal of AYUSH: Ayureveda, Yoga, Unani, Siddha and Homeopathy ISSN: 2321-6484 Volume 3, Issue 1 www.stmjournals.com

Bhojanottara Karma â&#x20AC;&#x201C; An Accentuated Ritual after Intake of Ahar Kasha Nath Samagandi1*, Jagriti Sharma Samagandi2, Kamalesh Kumar Sharma3 1 Department of Swasthavritta, National Institute of Ayurveda, Jaipur, India 2 Dept of Rasa Shastra and Baishyajja Kalpana, National Institute of Ayurveda, Jaipur, India 3 Department of Swasthavritta, National Institute of Ayurveda, Jaipur, India

Abstract Wellness is the way to achieve physical, mental, social, emotional and spiritual gratification. Ayurveda emphasizes that normalcy in terms of Guna and Karma of Tridosa (three humors) refers to a wellness of an individual, so the name Tri-Sthuna (three main pillars of Shareera). Ahara as the source of energy, Nidra as a state of energy conservation and Abrahmacarya as an act of energy consumption, all together as a Trayopastambha support in the maintenance of equilibrium of Tridosha. Ahara, as a source of nutrition and energy, directly relies upon digestion and its absorption. A health benefit of Ahara depends not only on the qualitative food ingestion, but also on the appropriateness in the digestion of consuming food. Suppression of digestive fire is an inevitable factor after food consumption; modern nutrition is lagging behind in guiding natural tips which are essential for maintaining the capacity of digestive fire to its optimum, for digestion, assimilation and absorption of consuming food. Ayurveda emphasizes these tips, but they are dispersed widely in Ayurveda excellence. Here the present review article is done to throw a ray of light on the glimpses of instructions under the title of Bhojanottara Karma, luck, Achamana, Tambula Sevana, Chankramana, etc., under one roof, which are needed for the proper utilization of consuming food.

Keywords: Ahara, bhojanottara karma, chankramana, digestion