Research & reviews a journal of drug design & discovery (vol1, issue2) by STM Journals Publication

eISSN: 2349-9036

Research & Reviews: A Journal of

Drug Design & Discovery RRJoDDD May - August 2014

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Internal Members Puneet Pandeya Manager Associate Editors Gargi Asha Jha Nupur Anand

Monika Malhotra Assistant Manager Assistant Editors Priyanka Aswal Aditya Sanyal Anupama Garg Sona Chahal Himani Pandey

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Dr. Bimlesh Lochab Industrial Tribology Machine Dynamics & Maintenance Engineering Centre (ITMMEC) Indian Institute of Technology Delhi, India.

Dr. Rajiv Prakash School of Materials Science and Technology, Institute of Technology, Banaras Hindu University, Varanasi, India.

Prof. S. Ramaprabhu Alternative Energy Technology Laboratory, Department of Physics, Indian Institute of Technology, Chennai, India.

Dr. Rakesh Kumar Assistant Professor, Department of Applied Chemistry, BIT Mesra, Patna, India.

STM Journal (s) Advisory Board

Dr. Baldev Raj Chairman, National Institute of Technology Puducherry, India. Former Director, Indira Gandhi Centre for Atomic Research, India.

Prof. Bankim Chandra Ray Professor and Head, Department of Metallurgical and Materials Engineering National Institute of Technology, Rourkela, India.

Dr. Hardev Singh Virk Professor Emeritus, Eternal University, Baru Sahib, India.

Dr. Baskar Kaliyamoorthy Associate Professor, Department of Civil Engineering National Institute of Technology Trichy, India.

Prof. D. N. Rao Professor, Department of Biochemistry, AIIMS, New Delhi, India.

Prof. Jugal Kishore Professor, Department of Community Medicine, Maulana Azad Medical College, New Delhi, India.

Dr. Ashish Runthala

Dr. Pankaj Poddar

Lecturer, Biological Sciences Group, Birla Institute of Technology & Science, Pilani Rajasthan, India.

Scientist, Physical & Materials Chemistry Division, National Chemical Laboratory, Pune, India.

Dr. Nandini Chatterjee Singh Associate Professor, National Brain Research Centre, Manesar, India.

STM Journal (s) Advisory Board & Editorial Board

Dr. Priyavrat Thareja

Dr. Rakesh Kumar

Head, Materials and Metallurgical Engineering Department, PEC University of Technology, Chandigarh, India.

Assistant Professor, Department of Applied Chemistry, BIT Mesra, Patna, India.

Dr. Shankargouda Patil

Dr. Shrikant Balkisan Dhoot

Asst. Prof., Department of Oral Pathology, KLE Society's Institute of Dental Sciences, Bangalore, India.

Head Research & Development, Nurture Earth R&D Pvt Ltd MIT Campus, Beed bypass road, Aurangabad, India.

Prof. Subash Chandra Mishra

Prof. Sundara Ramaprabhu

Professor, Metallurgical & Materials Engineering Department, NIT, Rourkela, India.

Professor, Department of Physics Indian Institute of Technology Madras, India.

Prof. Yuwaraj Marotrao Ghugal Professor and Head Department, Govt. College of Engineering Station Road, Osmanpura, Aurangabad, India.

Editorial Board

Dr. A Srinivasa Rao Professor & HOD Dept. of Pharmaceutical Analysis & QA Shri Vishnu College of Pharmacy Vishnupur, A.P, India.

Dr. Abhay Dharamsi Professor and Head Dept. of Pharmaceutics Maliba Pharmacy College Bardoli-Mahuva Road, Gujarat, India.

Dr. Amita Verma Head Dept. of Pharmaceutical Sciences, SHIATS-Deemed University, Allahabad, India.

Dr. Anita Mahapatra Assistant Professor, Dept. of Natural Products NIPER, Ahmedabad, Gujarat, India.

Dr. Arabinda Nayak HOD, Department of Pharmacology, Gujarat Technological University, India.

Dr. Deepika Singh Medical Chemistry Division CSIR - Indian Institute of Integrative Medicine, Canal Road, Jammu, India.

Dr. George D Geromichalos Head, Molecular Modeling & Drug Design Symeonidion Research Center Theagenion Cancer Hospital, Greece.

Dr. Jayarajakumar Kalaimani Faculty of Pharmacy, AIMST University, Bedong, Malaysia.

Dr. K.K Sivakumar Assistant Professor, Department of Pharmaceutical Chemistry, KMCH College of Pharmacy, Coimbatore, India.

Miss Maushmi Shailesh Kumar Assistant Professor, Dept. of Pharmaceutical Biotechnology, SPPSPTM, NMIMS University, Mumbai, India.

Dr Murugesan Sankaran Assistant Professor, Department of Pharmacy, Birla Institute of Technology, Pilani, Rajasthan, India.

Dr. Muthyala Murali Krishna Kumar Assistant Professor, College of Pharmaceutical Sciences, Andhra, India.

Editorial Board

Mr. T Durai Ananda Kumar

Dr. Suneel .I. Majagi

Sr Assistant Professor, Dept of Pharmaceutical Chemistry, Gokaraju Rangaraju College of Pharmacy, Nizampet, Hyderabad, India.

Associate Professor Department of Pharmacology J.N.Medical College Belgaum, Karnataka, India.

Dr. Udayabanu Malairaman

Dr. V. Ravichandran Faculty of Pharmacy, AIMST University, Semeling, Kedah, Malaysia.

Assistant Professor, Department of Pharmacy, Jaypee University of Information Technology, Solan, H.P, India.

Dr. Santanu Chakraborty

Dr. Jenifer Solomon Rajan

Assistant Professor, Department: Pharmaceutics, Dr. B. C. Roy Engineering College, Kolkata, India.

Asst. Profesor, Department of Biotechnology,Bon secours College for Womens, Thanjavur, Tamilnadu, India.

Dr. Nahlah Elkudsiah Ismail

Dr. Sandip Prabhakar Zine

Faculty of Pharmacy, Universiti Teknologi MARA (UiTM) Puncak Alam Campus, Bandar Puncak Alam, Selangor, Malaysia.

Assistant Professor, Department of Pharmaceutical Chemistry, Vivekanand Education Society's College of Pharmacy, Mumbai, India.

Dr. Shihabuddin Bin Ahmad Senior Lecturer Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam, Selangor, Malaysia.

Dr. Mudit Dixit Head-Department of Drug Regulatory Affairs & Assistant Professor (Pharmaceutics)(Senior Grade), NGSM Institute of Pharmaceutical Sciences, Mangalore, India.

Ms. Soh Yee Chang Faculty of Pharmacy UiTM Puncak Alam Campus Malaysia.

Editorial Board

Dr. Nishant Shukla Lecturer Head of Kayachikitsa , Coordinatordaivyavyapashrya chikitsa Kendra, India.

Dr. P. Senthil Kumar Assistant Professor, KMCH College of Pharmacy, Coimbatore, India.

Dr. Poonam Singh Scientist CSIR-Central Drug Research Institute, Lucknow, India.

Dr. Pratap Chandra Acharya Assistant Professor, Dept. of Pharmaceutical Chemistry, SPPSPTM, SVKM'S NMIMS University, Mumbai, India.

Mrs. Priti Jain Dept. of Pharmacy, Birla Institute of Technology and Science, Pilani, India.

Dr. R.K Singh Senior Principal Scientist, CDRI, Lucknow, India.

Dr. Sadia Sultan Lecturer, Faculty of Pharmacy, UiTM Puncak Alam Campus Bandar Puncak Alam Selangor, Malaysia.

Dr. Sanghapal D. Sawant CSIR-Indian Institute of Integrative Medicine, Jammu, India.

Dr. Sapna Shrikumar Principal, Moulana College of Pharmacy, Angadtppuram , Perinthalmanna, Malappuram, Kerala, India.

Dr. Shashank K Singh Senior Scientist, CSIR-Indian Institute of Integrative Medicine ,Canal Road Jammu, India.

Director's Desk

STM JOURNALS

I take the privilege to present the print version for the Volume 1 Issue (2) of Research & Reviews: A Journal of Drug Design and Discovery. The intension of RRJoDDD is to create an atmosphere that stimulates creativeness, research and growth in the area of Drug Design and Discovery. The development and growth of the mankind is the consequence of brilliant Research done by eminent Scientists and Engineers in every field. RRJoDDD provides an outlet for Research findings and reviews in areas of Drug Design and Discovery found to be relevant for National and International recent developments & research initiative. The aim and scope of the Journal is to provide an academic medium and an important reference for the advancement and dissemination of Research results that support high level learning, teaching and research in the domain of Drug Design and Discovery. Finally, and Authors for their continued support and invaluable contributions and suggestions in the form of authoring I express my sincere gratitude and thanks to our Editorial/ Reviewer board write ups/ reviewing and providing constructive comments for the advancement of the journals. With regards to their due continuous support and co-operation, we have been able to publish quality Research/Reviews findings for our customers base. I hope you will enjoy reading this issue and we welcome your feedback on any aspect of the Journal.

Dr. Archana Mehrotra Director STM Journals

Research & Reviews: A Journal of Drug Design & Discovery

Contents

1. Antibacterial Activity and Preliminary Phytochemical Screening of the Extracts of the Bark of Moringa oleifera Jenifer S, Priya S

2. Antibacterial Activity of Leaf and Flower Extract of Lablab purpureus against Clinical Isolates of Staphylococcus aureus Priya S., Jenifer S.

3. Single Nucleotide Polymorphism in CYP17 and CYP19 in Breast Cancer Laveena D. K., Jenifer S., Singh S. J. S.

4. Pharmacology of Herbal Drugs: Ayurvedic Approach Nishant Shukla

5. A Comprehensive Literary Review on Heavenly Elixirâ&#x20AC;&#x201C;Amrita Patil Shilpa, Chaudhary Anandkumar