Research & reviewsjournal of oncology and hematology(vol3, issue1) by STM Journals Publication

(RRJoOH)

eISSN: 2319-3387

Research & Reviews

Journal of

Oncology & Hematology Jan - April 2014

(RRJHS)

sCurrent Aspects of Nanomedicine for Cancer.

sEffectiveness of an Informational Booklet on Prevention of Cervical Cancer in

Terms of Knowledge and Attitude of Female College Students. sEfficacy of Home Based Progressive Resistance Exercise Program Verses Aerobic

Exercise Program in Improving Quality of Life in Elderly Subjects. sTreatment Planning Techniques in External Beam Photon Radiation Therapy.

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Research & Reviews: Journal of Oncology and Hematology (ISSN: 2319-3387) Focus and Scope Covers † Radiation Oncology. † Surgical Oncology. † Medical Oncology. † Interventional Oncology. † Gynecologic Oncology. †

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Prof. Satheesan Balasubramanian Director, Professor and Head of Department of Surgical Oncology Malabar Cancer Centre, Thlassery, Kannur, India.

Prof Thangarajan Rajkumar Professor and Head, Dept. of Molecular Oncology,Cancer Institute (WIA), Adyar, Madras, India.

Professor Keechilat Pavithran Department of Medicaloncology and Hematology, Amrita Institute of Medical Sciences P.O. AIMS Ponekkara Cochin, India.

Chinmay Kumar Panda Dept. of Oncogene Regulation Chittaranjan National Cancer Institute, Kolkata, India.

Dr. Rakesh Jalali Professor of Radiation Oncology Convener, NeuroOncology Group, Tata Memorial Hospital Parel, Mumbai India.

Dr Dillip Kumar Parida Head, Department of Oncology, Maw Diang Diang, Shillong, Meghalaya, India.

Dr. Pritha Ray Assistant Professor and Principle Investigator Tata Memorial Centre, India.

Dr. Lalit Kumar Dr. B.R. Ambedkar Institute-Rotary Cancer Hospital, AIIMS Department of Medical Oncology, India.

Fayaz Ahmad Malik Scientist Department of Cancer Pharmacology Indian Institute of Integrative Medicine, India.

Ms Krishna P. Gupta Carcinogenesis Labratory,Indian Institute of Toxicology Research,M.G.Marg, Lucknow, India.

Dr Arun Chaturvedi Senior Consultant & Head of Surgical Oncology Sahara India Medical Institute Ltd. Lucknow, India.

Dr. D.K. Vijaykumar Prof. & Head, Dept. of Surgical Oncology Amrita Institute of Medical Sciences & Research CentrePonekkara P.O., Cochin Kerala, India.

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I take the privilege to present the hard copy compilation for the [Volume 3 Issue (1)] of Research & Reviews: Journal of Oncology and Hematology. The intension of RRJoOH is to create an atmosphere that stimulates creativeness, research and growth in the area of Oncology and Hematology. The development and growth of the mankind is the consequence of brilliant Research done by eminent Scientists and Engineers in every field. RRJoOH provides an outlet for Research findings and reviews in areas of Oncology and Hematology found to be relevant for National and International recent developments & research initiative. The aim and scope of the Journal is to provide an academic medium and an important reference for the advancement and dissemination of Research results that support high level learning, teaching and research in the domain of Oncology and Hematology. Finally, I express my sincere gratitude and thanks to our Editorial/ Reviewer board and Authors for their continued support and invaluable contributions and suggestions in the form of authoring writeups/ reviewing and providing constructive comments for the advancement of the journals. With regards to their due continuous support and co-operation, we have been able to publish quality Research/Reviews findings for our customers base. I hope you will enjoy reading this issue and we welcome your feedback on any aspect of the Journal.

Dr. Archana Mehrotra Director STM Journals

Research & Reviews: Journal of Oncology and Hematology

Contents

1. Current Aspects of Nanomedicine for Cancer Markna J. H., Raval C. S., Shah N. A.

2. Effectiveness of an Informational Booklet on Prevention of Cervical Cancer in Terms of Knowledge and Attitude of Female College Students Sharma P., Kumari V., Bishnoi A.

3. Efficacy of Home Based Progressive Resistance Exercise Program Verses Aerobic Exercise Program in Improving Quality of Life in Elderly Subjects Improving Quality of Life in Elderly Subjects Choudhuri B., Patra P

4. Treatment Planning Techniques in External Beam Photon Radiation Therapy Michieka A

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387 Volume 3, Issue 1 www.stmjournals.com

Current Aspects of Nanomedicine for Cancer Markna J. H.1*, Raval C. S.1, Shah N. A.2 1

Department of Nanotechnology, V. V. P. Engineering College, Gujarat Technological University, Rajkot-360005, India 2 Department of Electronics, Saurashtra University, Rajkot-360005, India

Abstract Nanotechnology is an advanced as well as budding branch of the science. It involves the studies of materials at the nano scale. It has demonstrated its enormous applications in almost every discipline like in biotechnology, medicines, electronics, etc. Among its nanotechnology, when applied to medical specialties than it is called nanomedicines. Nanomedicines are surprisingly effective in case of cancer. Nanomedicines provide better drug delivery as well as more efficacious against tumor cells and with the help of various nanoparticles better imaging of cancerous tissues can be possible. This article briefly describes the current as well as future trends of nanomedicines in the case of cancers. It also pronounces benefits of these advanced medicines over the traditional medicines.

Keywords: Nanotechnology, nanomedicines, cancer, nano particles, drug delivery

Page 1

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387 Volume 3, Issue 1 www.stmjournals.com

Effectiveness of an Informational Booklet on Prevention of Cervical Cancer in Terms of Knowledge and Attitude of Female College Students Sharma P., Kumari V.*, Bishnoi A. M.M. College of Nursing, M.M. University, Mullana, Ambala, Haryana, India

Abstract Cancer of the uterine cervix is the leading cause of mortality and morbidity among women worldwide. An experimental study was undertaken with the objectives to assess and evaluate the effectiveness of an informational booklet on prevention of cervical cancer in terms of knowledge and attitude among female college students before and after the administration of informational booklet. The research design adopted for the study was one-group pre-test post-test design. The sample comprised of 150 female college students of M.M. Engineering College, Mullana which were selected by convenience sampling. A knowledge questionnaire was used to assess knowledge of female college students regarding prevention of cervical cancer and 5-point. Attitude scale to assess attitude of female college students regarding prevention of cervical cancer. Paired “t” test was used to find out the significance of difference in mean pretest and posttest knowledge and attitude score. The findings suggest that the mean post test knowledge score (25.9) was significantly higher than mean pre-test knowledge score (20.2) at p < 0.05. The subjects after exposure to the informational booklet gained a significantly higher attitude score (96.56 versus 68.11 at p < .05.) The study concluded that informational booklet was effective in enhancing knowledge as well as modifying the attitude of female college students on prevention of cervical cancer.

Keywords: Cervical cancer, informational booklet, knowledge and attitude

Page 5

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387 Volume 3, Issue 1 www.stmjournals.com

Efficacy of Home Based Progressive Resistance Exercise Program Verses Aerobic Exercise Program in Improving Quality of Life in Elderly Subjects Choudhuri B., Patra P.* Department of Physiotherapy, Dolphin (P.G.) Institute, Dehradun, India Abstract The purpose of the present study is to compare the effectiveness of resistance training versus aerobic training for reduction of cancer related fatigue and improvement in quality of life. A comparative study. Participants were selected from The Government Cancer Hospital, Agartala and few private cancer clinics. A total of 20 subjects were recruited for the study on the basis of inclusion and exclusion criteria after signing the informed consent form. MFSI-SF was used to measure cancer related fatigue and QOLS was used to measure quality of life. The result of present study indicates that both resistance and aerobic training improved the quality of life in subjects with CRF. However, resistance trainings were more effective in both physical score (PS) and mental score (MS). The present study concluded that resistance training is more effective in reducing fatigue in subjects with CRF as compared to aerobic exercise.

Keywords: cancer related fatigue (CRF), resisted training, aerobic training, quality of life (QOL), multidimensional fatigue symptom inventory â&#x20AC;&#x201C; short form (MFSI-SF), quality of life scale (QOLS)

Research & Reviews: Journal of Oncology and Hematology ISSN: 2319 -3387 Volume 3, Issue 1 www.stmjournals.com

Treatment Planning Techniques in External Beam Photon Radiation Therapy Michieka A.* Interdisciplinary Research, University of Nairobi, Nairobi, Kenya Abstract Volumetric modulated radiation therapy (VMAT) is a modern treatment technique in radiation therapy, and it delivers conformal radiation dose to the tumor while minimizing dose to the normal tissues. The beam delivery is done in the form of one or multiple arcs, with gantry rotating around the treatment isocenter. A number of literature suggests that VMAT could be an attractive option to treat prostate cancer. However, there is no consensus about which treatment technique produces better dosimetric results. In this article, some of the factors which may influence the results of the studies are addressed. Furthermore, major dosimetric findings comparing different treatment planning techniques for prostate cancer in external beam photon radiation therapy are summarized.

Keywords: Treatment planning, VMAT, prostate cancer