Antibiotic Therapy in Small Animals

PRESENTATION

BROCHURE Handbook of antimicrobial therapy in companion animals

Antibiotic Therapy in Small Animals Victoria Villagrasa Sebastián Gemma León Bello Mireia García Roselló

in Small Animals

Handbook of antimicrobial therapy in companion animals

Antibiotic Therapy

Antibiotic Therapy in Small Animals Victoria Villagrasa Sebastián Gemma León Bello Mireia García Roselló

PY092859_Antimicrobial_therapy_COVER_SERVET.indd 3

10/7/18 10:09

AUTHOR: Victoria Villagrasa Sebastián, Gemma León

Bello, Mireia García Roselló.

FORMAT: 17 × 24 cm.

NUMBER OF PAGES:112.

BINDING: hardcover.

ESTIMATED

RETAIL PRICE

€45

eBook included

The objectives of this guide, which is aimed at small veterinary surgeons, is to provide guidelines on the use of antibiotics in daily practice and refresh the reader’s knowledge of the pharmacokinetics, indications, and contraindications of antibiotics.

It includes numerous figures, tables and charts that summarise the dosage forms available and the treatment protocols for each antibiotic family, so as to help practitioners choose the most suitable antibiotic for each case and thus achieve maximum therapeutic efficacy while preventing the development of resistance.

Presentation of the book Small animal veterinary medicine is complex and resembles human medicine in that each case is treated individually based on the patient’s clinical signs and physiopathological features. The range of drugs available for veterinary use is now vast and a wide variety of antibiotic families are used to treat infectious diseases affecting small animals, always based on the therapeutic indications for each family and the microorganisms present in each situation.

The prescription of human drugs for use in animals under the rules of the “cascade� is decreasing nowadays thanks to the higher availability of veterinary antibiotics. However, this recent increase in the range of molecules available may confuse veterinary surgeons and make it more difficult for them to choose the most suitable antibiotic for each patient.

For this reason, this guide provides veterinary surgeons with a classification of the antibiotics for veterinary use indicated in small animals, as well as therapeutic protocols to increase drug efficacy and thereby minimise the development of antibiotic resistance.

This guide on antibiotic therapy is the result of the joint efforts of several specialists in pharmacology and small animal internal medicine, .

The authors Victoria Villagrasa Sebastián PhD in Pharmaceutical Sciences from the University of Valencia, Spain, in 1998. She is currently professor at CEU-Cardenal Herrera University (Valencia), where she teaches Pharmacology to undergraduate students of Veterinary Medicine and Physiotherapy. She has also taught students of Medicine at the University of Valencia, as well as the postgraduate course titled “Use of anti-infectious drugs in prophylaxis and therapeutics” at CEU-Cardenal Herrera University. She currently teaches master’s-level courses in the field of pharmaceutical healthcare and consumer health and food safety at CEU-Cardenal Herrera University. She has performed this activity concurrently with research, supervised various PhD theses and collaborated in multiple projects and research contracts with different pharmaceutical companies. All this has resulted in the publication of many articles in peer-reviewed scientific journals specialised in pharmacology.

She has coauthored two editions of the book Manual de farmacología : guía para el uso racional del medicamento (Pharmacology Manual. A Guide to the Rational Use of Drugs), as well as many book chapters and specialised international scientific publications. She is a member of the Committee for the Evaluation of Drugs for Veterinary Use of the Spanish Medicines and Health Products Agency (AEMPS).

Gemma León Bello PhD in Public Health from Miguel Hernández University, Elche, Spain (2015). Joint master’s degree in Environmental Health from the University of Valencia, Menéndez Pelayo International University and the “Universitat Empresa” Foundation (2003). She holds a diploma in Methodology of Research in Health Sciences by the Health Studies School of Valencia (EVES) and a Diploma in Public Health by the Spanish National School of Health.

She also obtained a diploma in Veterinary Pharmaccology in 2014. She is currently a lecturer at the Faculty of Veterinary Sciences of CEU Cardenal Herrera University (Valencia), where she teaches Pharmacology. She is in charge of medicines management at the Veterinary Teaching Hospital, CEU Cardenal Herrera University. She has participated in several research projects and is the author and coauthor of several scientific publications and teaching materials.

PhD in Veterinary Medicine by the Polytechnic University of Valencia in 2004. She obtained a postgraduate diploma in small animal medicine in 2014, and is the coordinator for the CEU-Cardenal Herrera University postgraduate programme in small animal medicine.

She has participated in many research projects on neuronal regeneration at the Príncipe Felipe Research Center (Valencia) . Veterinary surgeon at the CEU-Cardenal Herrera University Veterinary Teaching Hospital since 2008, and director of the hospital since 2013.

She has coauthored various textbooks and scientific articles published in international journals. She has participated in many research projects and is currently a member of a research group on experimental and applied veterinary surgery.

hkeita/shutterstock.com

Mireia García Roselló

Collaborators Encarna Castillo García Professor in the Department of Pharmaceutical Studies, Faculty of Health Sciences, CEUCardenal Herrera University

Empar García Roselló Associate professor in the Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

Ángel María Hernández Guerra Professor in the Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

Jaume Jordá Moret Associate professor in the Department of Animal Health and Production, Veterinary Public Health and Food Sciences and Technology, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

María López Murcia Professor in the Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

Clara Marín Orenga Professor in the Department of Animal Health and Production, Veterinary Public Health and Food Sciences and Technology , Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

Marta Marín Vázquez Lecturer in the Department of Pharmaceutical Studies, Faculty of Health Sciences, CEUCardenal Herrera University.

Aloma Mayordomo Febrer Lecturer in the Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

María Raquel Miquel González Associate professor in the Department of Pharmaceutical Studies, Faculty of Health Sciences, CEU-Cardenal Herrera University.

María Amparo Sanahuja Santafé Associate professor in the Department of Pharmaceutical Studies, Faculty of Health Sciences, CEU-Cardenal Herrera University.

María Sebastián Morelló Associate professor in the Department of Pharmaceutical Studies, Faculty of Health Sciences, CEU-Cardenal Herrera University.

Professor in the Department of Animal Health and Production, Veterinary Public Health and Food Sciences and Technology, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

Eliseo Zuriaga Sanchís Associate professor in the Department of Animal Medicine and Surgery, Faculty of Veterinary Sciences, CEU-Cardenal Herrera University.

hkeita/shutterstock.com

Santiago Vega García

Handbook of antimicrobial therapy in companion animals

Antibiotic Therapy in Small Animals Victoria Villagrasa Sebastián Gemma León Bello Mireia García Roselló

PY092859_Antimicrobial_therapy_COVER_SERVET.indd 3

10/7/18 10:09

Table of contents 1. Introduction to antimicrobial therapy Definition of antibiotic History of antiobiotic medicines

Cephalosporins Pharmacokinetics Adverse effects Interactions and contraindications Spectrum of action

General classification of the main families of antibiotics

Bacterial resistance

Definition of related terms

Dosage forms and treatment protocol

Main mechanisms of bacterial resistance

2. Guidelines for appropriate use of antibiotics

Therapeutic use

Carbapenems Pharmacokinetics Adverse effects Interactions and contraindications

Introduction

Spectrum of action

Scope of the problem

Bacterial resistance

Role of health authorities

Therapeutic use

Role of veterinary practitioners Cascade use of products due to unavailability of authorised veterinary medicines

3. β-Lactams

Dosage forms and treatment protocol

Monobactams Pharmacokinetics Adverse effects Interactions and contraindications Spectrum of action

Mechanism of action

Therapeutic use

Penicillins

Dosage forms and treatment protocol

Pharmacokinetics

β-Lactamase inhibitors

Adverse effects

Pharmacokinetics

Interactions and contraindications

Adverse effects

Spectrum of action

Interactions and contraindications

Bacterial resistance

Spectrum of action

Therapeutic use

Therapeutic use

Dosage forms and treatment protocol

Dosage forms and treatment protocol

4. Macrolides

7. Tetraciclinas

Mechanism of action

Mechanism of action

Pharmacokinetics

Pharmacokinetics

Adverse effects

Adverse effects

Interactions and contraindications

Interactions and contraindications

Spectrum of action

Spectrum of action

Bacterial resistance

Bacterial resistance

Therapeutic use

Therapeutic use

Dosage forms and treatment protocol

Dosage forms and treatment protocol

5. Aminoglycosides Mechanism of action Pharmacokinetics

Case study

8. Sulfonamides and trimethoprim

Adverse effects

Mechanism of action

Interactions and contraindications

Pharmacokinetics

Spectrum of action

Adverse effects

Bacterial resistance

Interactions and contraindications

Therapeutic use

Spectrum of action

Dosage forms and treatment protocol

Bacterial resistance

Case study

Therapeutic use

6. Quinolones Mechanism of action Pharmacokinetics

Dosage forms and treatment protocol

9. Chloramphenicol and metronidazole

Adverse effects

Chloramphenicol

Interactions and contraindications

Pharmacokinetics

Spectrum of action

Adverse effects

Bacterial resistance

Interactions and contraindications

Therapeutic use Dosage forms and treatment protocol Case study

Spectrum of action Therapeutic use Dosage forms and treatment protocol

Metronidazole

Interactions and contraindications

Pharmacokinetics

Spectrum of action

Adverse effects

Bacterial resistance

Interactions and contraindications

Therapeutic use

Spectrum of action

Dosage forms and treatment protocol

Therapeutic use Dosage forms and treatment protocol

10. Lincosamides: lincomycin and clindamycin

Bacitracin Mechanism of action Pharmacokinetics Adverse effects Interactions and contraindications

Mechanism of action

Spectrum of action

Pharmacokinetics

Bacterial resistance

Adverse effects

Therapeutic use

Interactions and contraindications

Dosage forms and treatment protoco

Spectrum of action Bacterial resistance Therapeutic use Dosage forms and treatment protocol Case study

11. Polypeptide antibiotics Polymyxins

12. Antibiotic therapy tables for most common infections Preliminary comments Oral cavity infections Ear, nose and throat infections Nervous system infections Skin infections Respiratory tract infections

Mechanism of action

Sepsis and bacteriaemia

Pharmacokinetics

Antibiotic therapy tables according to location of infection

Adverse effects

The publishing strength of Grupo AsĂ­s Editorial Servet, a division of Grupo AsĂ­s, has become one of the reference publishing companies in the veterinary sector worldwide. More than 15 years of experience in the publishing of contents about veterinary medicine guarantees the quality of its work. With a wide national and international distribution, the books in its catalogue are present in many different countries and have been translated into nine languages to date: English, French, Portuguese, German, Italian, Turkish, Japanese, Russian and Chinese.

Its identifying characteristic is a large multidisciplinary team formed by doctors and graduates in Veterinary Medicine and Fine Arts, and specialised designers with a great knowledge of the sector in which they work. Every book is subject to thorough technical and linguistic reviews and analyses, which allow the creation of works with a unique design and excellent contents.

Servet works with the most renowned national and international authors to include the topics most demanded by veterinary surgeons in its catalogue. In addition to its own works, Servet also prepares books for companies and the main multinational companies in the sector are among its clients.

Communication services Online visualisation of the sample chapter.

Presentation brochure in PDF format, compatible with mobile devices.

Servet (División de Grupo Asís Biomedia S.L.) Centro Empresarial El Trovador, planta 8, oficina I Plaza Antonio Beltrán Martínez, 1 • 50002 Zaragoza (España) Tel.: +34 976 461 480 • Fax: +34 976 423 000 • www.grupoasis.com