SPONSORED CONTENT
TridAnt
INFECTION PREVENTION INFRASTRUCTURE ARJUN LUTHRA, COMMERCIAL DIRECTOR, BIOINTERACTIONS, EXPLAINS HOW MULTI-ACTION TECHNOLOGY IS A STRAIGHTFORWARD SOLUTION TO FIGHT COVID-19, PREVENT FUTURE PANDEMICS AND ENHANCE GLOBAL HEALTHCARE INFRASTRUCTURE.
T
he case for revolutionary technologies and solutions that greatly enhance our quality of living has never been more important than now. Innovations that protect and enhance our daily routines are in constant demand and are especially critical considering the global Covid-19 pandemic. As the pandemic has persisted, our healthcare services and innovations have battled to keep up with the viral mutations as well as mitigate impact to core areas of healthcare services. This highlights the importance of a preventative measure to be in place so we can return to a better normal. The prevention measure must focus on confronting the current and future variants of Covid-19, preventing other harmful pathogens in our daily lives, as well as enhancing global infrastructure to prevent another pandemic from occurring. THE ROLE OF MATERIALS Materials play a critical role in improving the performance of technology and can improve the applicability of the products. The antimicrobial efficacy of materials involves critical interactions between the pathogen and surface interface, and the successes of applications
depend on a variety of biological events occurring at this interface. These events intensify the complications, which must be addressed during innovation and development. The challenge of infection prevention will help long-term prevention mechanisms which enhance medical devices as well as consumer applications. The biological events which occur at the pathogen-surface interface is critical to improving the prevention technology against pathogens. Biological responses are complex processes which are governed by a variety of factors. These factors range from surface properties, which include the chemistry, topography, wettability, and composition of a surface, to the biological entities present at the interface. Infections on surfaces have long been studied as they pose a significant challenge which has impeded long-term medical device applications. A variety of preventative techniques including silver, copper, and other chemistries used on medical devices have proven not to be significantly effective and highlight the need for an innovative solution. It has been seen in a randomized study of surface treatments to prevent infections that silver surface treatments have failed to reduce infection rates. It has also been seen that the use of silverimpregnated collagen cuffs can impede catheter fixation due to the killing of fibroblasts and cause the catheter to dislodge, thereby highlighting the toxic effects of similar chemistries to silver technology on eukaryotic cells. Furthermore, it has been recommended that any catheter which has caused bacteremia should be immediately removed and only replaced once results of blood cultures normalised. This highlights the difficulty previous technologies experienced when combating infections safely on a surface over long periods of time. Such as approach has had limited success, requiring the use of antibiotics which leads to resistance and further complications. The biological events that occur on a surface are a complex result of interactions between the surface and the proteins and cells, which are present at the pathogen-surface interface. These complex challenges require a multiaction material which considers all these varying factors in one straightforward technology. Multi-action materials provide a high-performance surface which prevents pathogen growth, enhances protection durability, and uses safe components all in one straight-forward solution. THE POWER OF PARTNERSHIPS BioInteractions Ltd and Phoel Ltd have partnered together to provide TridAnt®, the most advanced infection prevention infrastructure that enhances the control of pathogens in high-risk environments such as hospitals and GP practices. TridAnt® technology ensures broad spectrum protection of up to 99.99% against bacteria, viruses, and yeast as well as enhanced durability of up to 365 days — all while using technology comprised of chemistry which has been safe enough to use on medical devices for decades.
26
WWW.MEDICALPLASTICSNEWS.COM
