Chemical Today March 2017 by worldofchemicals.com

March 2017 | Volume 1 | Issue 10 | ₹200 www.worldofchemicals.com

Sector View Skin Cosmetics

Expert Viewpoint

Surfactants F&B Enzymes Construction Chemicals

Logistics

Supply Chain Interview

‘SUPER’ SKINCARE

WITH ‘SUPER’ FOOD

SuperFood to

SuperSkin

n today’s world, youngsters are more focused on grooming and improving their appearance. To enhance their personality, across the world youngsters are using more of skin brightening, skin whitening creams or lotions. Added to this, the changing lifestyles of consumers, increasing incomes and rising importance of beautification, has helped grow the global cosmetic skin care market. The skin care market is also seeing use of natural active ingredients based cosmetics, as a way to connect better with the environment conscious consumers. One of the key aspects in this area is the use of Superfoods making its way into the various creams and lotions. Everyone wants to be super fit, super healthy and super attractive. And to achieve this tag, the word ‘Superfood’ has taken the imagination of health conscious generation. So, while these Superfoods like kale, spinach, parsley are being tossed up into super healthy salads, the extracts of these Superfoods are widely being used as ingredients for cosmetics and skin care products to get super healthy skin. Hence, superfood is being treated not only as the elixir of health but also of the skin. So the next time you are munching on a bowl of healthy salad, do take notice, it could well become part of your face cream. Considering the trend towards natural products it is expected to create a market opportunity for natural and active cosmetic ingredients such as enzymes, botanical extracts and amino acids.

CHEMICAL

TODAY EDITOR IN CHIEF: Shivani Mody

PRINCIPAL CORRESPONDENT: Debarati Das GRAPHIC DESIGNER: Santosh Pradhan SUBSCRIPTION: subscriptions@worldofchemicals.com EDITORIAL: editorial@worldofchemicals.com BUSINESS HEAD: Naveen Suryavanshi

ADVERTISING: advt@worldofchemicals.com US & Europe naveen@worldofchemicals.com OVERSEAS PARTNER Eastern China Vivian Shang, +86-21 6289-5533 EXT 169, vivian@ringiertrade.com

Northern China and Southern China Maggie Liu, +86-20 8732-3316 EXT 9332, maggieliu@ringiertrade.com

International

Catch up on the latest development in the skin care cosmetics industry as we explore what super foods have to offer.

Mike Hay, +852 2369 8788 ext 11, mchhay@ringier.com.hk

Getting into the area of Soaps & Detergents, we notice the potential in the detergent chemicals and liquid detergent markets. One key trend on the rise is the use of high performance enzymes in the detergents. This is said to further become important keeping in mind the water pollution concerns and stricter environmental rules & regulations on an international level. A noteworthy fact is that both chemical and biotechnology companies are trying to compete with each other for greater market share by offering high-performance enzymes for liquid detergents. Moving ahead, the competition in the market is said to intensify further with more players entering the arena.

Kelly Wong, +886 4 2329 7318, wangyujung@ringier.com.hk

Also for this month, read what Dr Kurt Bock, President of Verband der Chemischen Industrie eV (VCI), has to say as he speaks on ‘Chemistry 4.0: Innovations for a dramatically changing world. Whether you want to give us a break, bouquet or brickbats, write to editorial@worldofchemicals.com

Taiwan

Printed by Jaison M Jose, Published by Bejoy Koroth on behalf of Kimberlite Softwares Pvt Ltd. and Printed at Josco Printers, #14, 12th Cross, Little Flower Hospital Road, R.M.Nagar, Bangalore 560016 and Published at Kimberlite Softwares Pvt Ltd., #46, Near ST. James Church, Dasarahalli, Bangalore 560024. Editor: Shivani Mody

Disclaimer: All rights reserved worldwide. No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, without the prior written permission of the publisher, except in the case of brief quotations embodied in critical reviews and certain other noncommercial uses permitted by copyright law. All photographs, unless otherwise specified, are used for illustrative purposes only. The publisher makes every effort to ensure that the magazine’s contents are correct. However, we accept no responsibility for any errors or omissions and for any loss or damage caused as an effect thereof. The information provided in this publication is for general use and may not be appropriate for the specific requirements of readers. Views and opinions expressed in this magazine are not necessarily those of the publisher.

EXPERT VIEWPOINT SURFACTANTS

20 R Kumaresan, Head, Business Unit, Industrial and Consumer Specialties, India, Clariant.

FOOD & BEVERAGE ENZYMES

22 Andrew Fordyce, Executive Vice President, Food & Beverages, Novozymes A/S.

INSIGHTS

CONSTRUCTION CHEMICALS

OIL & GAS, ENERGY AND CHEMICALS IN 2017

Sanjay Bahadur, Chief Executive Officer, Pidilite Industries Ltd.

SECTOR VIEW

Chemical Today

is a monthly magazine focused on chemistry & the chemical industry.

‘SUPER’ SKINCARE WITH ‘SUPER’ FOOD

PHYTONUTRIENTS

CONTENTS

QUOTES 04 NEWS NATIONAL 06 INTERNATIONAL 10 MAKE A DIFFERENCE 14 NORTH AMERICA OUTLOOK 16

EVENTS 18 GREEN CHEMISTRY

INNOVATION SURFACTANTS 40 SKIN REJUVENATION 28

GETTING A LITTLE EXTRA FROM FOOD

38 FEATURE

SOAPS & DETERGENTS

LOGISTICS

IT IN CHEMICALS

CASE STUDY CUTTING FLUIDS

INSIGHTS OUTLOOK 2017

MARKET UPDATES

INTERNATIONAL FOCUS NORTH AMERICA CLEANING CHEMICALS INDUSTRY

54 56

REPORT BREWING ENZYMES CAR WASH DETERGENTS & SOAPS COSMETIC INGREDIENTS SOY-BASED SURFACTANTS

58 60 62 64

ACADEMIC R&D

ACADEMIC SPEAK FOOD PROCESSING

R&D YOUNG TURKS

JOBS 78

PRODUCTS 82

Alok Gautam,

Country Logistics and Supply Chain Leader, Dow Chemical International Pvt Ltd (Dow India).

Chemical Today Magazine | March 2017

Dr Kurt Bock,

President of Verband der Chemischen Industrie eV (VCI) and Chief Executive of BASF.

EQUIPMENT CHEMICAL SENSORS MARKET 84 DISPENSING EQUIPMENT 86 EQUIPMENT 88

Published for March 2017.

QUOTES

he Indian specialty chemical industry is estimated to grow almost threefold its current size by the year 2020. This will be driven by demand from sectors like automotive, healthcare, agriculture, plastics, construction and FMCG. The country has a large population with low per-capita consumption of chemicals and a strong GDP growth outlook; this indicates the robust potential of India’s specialty chemical demand India is already acquiring a prominent position as a manufacturing base for multinational chemical majors. Several mature products in the sector have already been commoditized or are at risk of the same. Specialty chemical manufacturers need to strengthen their focus on niche applications and product innovation in order to protect their margins.

Dr Deepak Parikh,

Region Head – India, Clariant.

The government has addressed long pending issues to promote ease of doing business in pharma and medical devices sector. The correction of the inverted duty structure for medical devices, withdrawal of extension duty on imports to promote domestic manufacturing of bulk drugs and bringing about a fair, transparent, predictable and level playing field in the sector are some. Ananth Kumar, Minister of Chemical and Fertilizers, Government Of India.

India’s formulation exports have witnessed two block buster products going off patent between April-November 2015 namely Aripiprazole and Esomeprazole. There is no block buster drug going off patent during the current fiscal and the existing generics prices are coming down. This explains the causes for slowdown in pharma exports.

Ravi Uday Bhasker, Director General, Pharmexcil.

Chemical Today Magazine | March 2017

At present we are seeing some positive signs like more than expected monsoon, passage of GST amendment bill and expectation of better GDP growth, which will boost the economic activities across the country leading to consumption, which in turn will increase transportation. K K Kapur, CEO, Indag Rubber Limited. The rise of e-commerce and access to new technologies has accelerated counterfeiting and other forms of illicit trade. That makes fighting counterfeit medical products an ever-more urgent priority for pharma companies – both in terms of patient safety and brand reputation. Yann Ischi, Director, New Channels and Partnerships, SICPA. Farmed salmon remains one of the richest sources of omega-3s, which are beneficial for human health and supporting healthy brain development. And in fact, farmed salmon delivers more omega-3s than wild caught salmon. Douglas Tocher, Professor, Stirling University. Considered as one of the most needed tax reforms, the Goods and Services Tax (GST) will change the country’s taxation regime for good. GST will enhance the ease of doing business in India, provide greater transparency and empower supply chains to be integrated. We hope that this year’s budget focuses on the implementation of GST by June 2017, so that the Indian industries are able to consolidate their business under the new tax platform Shilip Kumar, Country President, Henkel India. Within the Volkswagen Group, we have a clear strategy for how we want to put battery-electric vehicles into series production across our brands and in many different market segments. However, a major qualification for success in the volume market is more powerful battery concepts. In Volkswagen Group R&D we are focusing on close cooperation, not only with industrial partners but also with the smart minds of the scientific community. Dr Ulrich Eichhorn, Head, Group R&D, Volkswagen AG. Using reverse osmosis for pre-treatment means we can reduce the consumption of specific chemicals for resin bed regeneration by around 60 percent. Ashraf Aly Mostafa, Project Manager, Alexandria Fertilizers Co (Alexfert). You can’t have healthy children without healthy mothers, and the future of every country depends on having both. We need the support of all partners if we’re going to achieve our goal of universal access to healthcare for every woman and every child. We’re grateful for this financial contribution by MSD for Mothers, the first Global Financing Facility received from a private sector. Jim Yong Kim, World Bank Group President. Right now, there is a huge, unmet demand for basic consumer goods in India. But this is changing fast with a vastly increasing middle class. As masterbatch producers, we see enormous opportunities in the steps India is taking to open up the domestic market and moving to higher quality products. We want to be part of that change. Jurg Weibel, Owner and Director, Granula AG.

Chemical Today Magazine | March 2017

NEWS NATIONAL

ONGC LIKELY TO ACQUIRE HINDUSTAN PETROLEUM IN $6.6 BN DEAL

Chemical Today Magazine | March 2017

ndia’s state-run Oil and Natural Gas Corporation (ONGC), will take control of Hindustan Petroleum Corporation Limited (HPCL) as part of the government’s plan to create an integrated public sector oil entity comparable with big global oil companies like Shell BP and ExxonMobil, top government officials told the leading business daily. The deal is worth to be Rs 44,000 crore ($6.6 billion) at current market prices. “It is a very big decision. A Cabinet note will soon be moved. The government of India will transfer its majority shareholding (of 51.11 percent in HPCL) to ONGC, which will then become the holding company of HPCL,” said one of the officials cited above. The move will stop short of a complete merger, which may take longer but the purpose will be served with this step, said the people cited above. “The deal comes following the government plans to integrate either HPCL or Bharat Petroleum Corp Ltd (BPCL) with ONGC in line with the February 1 budget announcement to - create an integrated public sector oil major which will be able to match the performance of international and domestic private sector oil and gas companies.” The newspaper had also reported that the status of all other oil companies such as Oil India Ltd (OIL) and Indian Oil Corp (IOC) would remain unchanged. ONGC’s exploration functions will be integrated with HPCL’s refining and distribution capabilities. HPCL, which owns and operates two major refineries in Mumbai and Visakhapatnam, has India’s largest lubricants unit and second largest pipeline network of 3,015 km apart from a vast marketing system. The thinking behind such vertical integration is that it will reduce risk-high crude oil prices will boost the exploration business and when they drop, the distribution segment will benefit. “The world over, the largest and most successful oil companies like Shell, BP and Exxon, are vertically integrated,” said an official, stressing that ONGCHPCL’s earnings will become more stable and investors will benefit from this reduced volatility. Source: Economic Times News

NEWS NATIONAL MEGHMANI FINECHEM PLANS TO SET UP CHLOROMETHANE PLANT IN DAHEJ

eghmani Finechem Ltd (MFL), a subsidiary of Meghmani Organics Ltd (MOL), plans to set up a chloromethane plant of 40,000 metric tonne per annum (MTPA) at Dahej, Gujarat, India with an investment of Rs 140 crores. It will produce methylene dichloride (MDC), chloroform and carbon tetra chloride. The plant will be established at the existing manufacturing facility of MFL situated at GIDC Dahej and will be commissioned in March 2018.

“MFL is in line with the company’s strategic intent of expanding its chemicals business. The basic advantage to set up CMS plant at the present complex is availability of ready infrastructure and usage of 41,000 metric tonne per annum of chlorine. This will help MFL in reducing the cost of production of CMS plant and profitability of the company,” said a company press release. Chloromethane plant will enable

AUROBINDO FORAYS INTO BIOSIMILARS DEVELOPMENT; ACQUIRES SWISS FIRM’S PRODUCTS

Meghmani Finechem to meet the growing needs of pharmaceutical and agrochemical customers for methylene dichloride, which is widely imported into the country. The CMS plant will also enable Meghmani Finechem to meet demand for raw material of refrigerant gases. MFL expects to achieve turnover of Rs 120 crores in full financial year operation of FY 2018-19.

TATA CHEMICALS TO SET UP TWO FACILITIES IN INDIA; INVESTS

Rs 565 CRORE

ata Chemicals plans to invest Rs 565 crore to set up two facilities in Andhra Pradesh and Gujarat, to manufacture soluble dietary fibres and silica, respectively. The company signed a Memorandum of Understanding with Andhra Pradesh government last month to seal a Rs 270 crore investment plan to set up a biotechnology unit in Nellore district for manufacturing soluble dietary fibres. Additionally, an investment of Rs 295 crore has been approved to set up a plant in Gujarat for manufacturing precipitated highly dispersible silica, a company press release said.

urobindo Pharma Limited announced the acquisition of four cell culture derived biosimilar products from Swiss firm, TL Biopharmaceutical AG. As part of this agreement, TL will supply all the developmental data for four molecules and Aurobindo will develop, commercialise and market these products globally.

strategic investment for future growth and will position Aurobindo as a strong player in the rapidly evolving biosimilars landscape. Building on these first four products licensed from TL, Aurobindo is expanding its diverse portfolio of eight more next wave of biosimilars ensuring a strong and diverse products pipeline.

Aurobindo Pharma claims that the branded market size of these four biosimilars, three of them monoclonal antibodies in oncology is very promising. Regulatory filing for these products is expected to happen during 2020-22. Aurobindo is preparing to take its lead molecule from this transaction, a Bevacizumab biosimilar, for clinical trials in 2017. Bevacizumab is an anti-antiogenesis drug used in treating multiple-cancers including metastatic colon or rectal cancer, non-squamous and non-small cell lung cancers. Aurobindo Pharma said that this transaction is a

“We are impressed with TL’s product development as these are developed to the highest standards of biosimilarity. This acquisition is in-line with our strategy of investing in complex products and is an important first step towards establishing Aurobindo’s global biosimilars portfolio,” said N Govindarajan, managing director, Aurobindo Pharma Limited. Aurobindo has set up a fully functional R&D center for biologics development and is also establishing a state-of-art manufacturing facility in Hyderabad, Telangana which would be ready by second quarter of 2018.

Chemical Today Magazine | March 2017

“These investments in innovative specialty businesses mark a significant milestone in our journey to build technology enabled differentiation in our products and brands. With our investment in Gujarat, we are aiming to add value to our soda ash business, and through investment in nutritional solutions business in Andhra, we aim to serve demanding and critical segments such as Early Life Nutrition (infant nutrition) and medical foods through ingredients, formulations and customised products,” said R Mukundan, managing director and CEO, Tata Chemicals. While dispersible silica, a specialty chemical, represents downstream value addition to TCL’s soda ash business, precipitated silica has applications in several industries including rubber, coatings, pesticides and oral care, and seven patents have already been filed for the company’s product.

BENGALURU TO GET PHARMA & MEDICAL TECHNOLOGY ZONE

he Centre, in partnership with the State government planning to establish an exclusive zone for pharmaceuticals and medical technology at Bengaluru to boost domestic production of these products under the Make in India initiative. “Bengaluru, being the hub of information technology and skilled manpower, will prove to be the ideal location to set up a pharma and med tech zone and the ministry will work with the State Government to establish it soon,” said Ananth Kumar, minister for chemicals & fertilizers, during the India Pharma & India Medical Device International Conference. Mansukh Lal Mandaviya, minister of state for chemicals & fertilizers, added that the recent approval of the pharma and med tech zone in Andhra Pradesh has attracted over 30 investment proposals from domestic and international pharma

Chemical Today Magazine | March 2017

companies which has the potential to reduce the manufacturing cost of drugs and medical devices by around 30 percent as compared to global prices.

He further added that the government has addressed long pending issues to promote Ease of Doing Business in pharma and medical devices sector. He said,

Talking about the achievements of the pharma sector, Ananth Kumar said that the industry has achieved a compounded annual growth rate (CAGR) of over 15 percent and expressed confidence that the sector would be worth $55 billion by 2020 from the present $32 billion. India accounts for around 20 percent of the world’s generic medicine supply chain, exporting to over 250 countries globally. Indian pharma industry provides over 60 percent of global vaccines.

“Correction of the inverted duty structure for medical devices, withdrawal of extension duty on imports to promote domestic manufacturing of bulk drugs and bringing about a fair, transparent, predictable and level playing field in the sector etc, has been done by the government. The government will maintain this stability for the sector in the future as well.”

“In this fiscal year, the Indian Pharma sector has received Foreign Direct Investment (FDI) close to $14 billion and has generated employment for over 2.5 million people across India,” said Kumar.

“The state pharma industry constitutes 264 manufacturing units that include small-medium, large, public sector and multinational companies. The state stands fifth in pharmaceuticals exports with 40 percent of its pharma produce being exported overseas,” said Siddaramaiah, Karnataka chief minister.

NEWS INTERNATIONAL TRONOX TO BUY CRISTAL TIO2 BUSINESS IN $1.67 BILLION DEAL COMPANY INTENDS TO SELL ITS ALKALI BUSINESS.

ronox Limited (TROX) has entered into a definitive agreement to acquire the titanium dioxide (TiO2) business of Cristal, for $1.673 billion of cash and Class A ordinary shares representing 24 percent ownership in proforma Tronox.

TiO2 pigment producer with assets and operations on six continents. The combined company will operate 11 TiO2 pigment plants in eight countries with a total capacity of 1.3 million metric tonnes per annum.

Cristal is a privately held global chemical and mining company. It is a subsidiary of Saudi Arabia’s National Industrialization Co (Tasnee).

Closing is expected to occur before the first quarter 2018. Tronox anticipates completing the sale of its Alkali business in the second half of 2017.

Simultaneously with this announcement, the company announced its intent to begin a process to sell its Alkali business. The combination of the TiO2 businesses of Tronox and Cristal creates the world’s largest and most highly integrated

Tom Casey will remain chairman and CEO of the company (Tronox) and it’s corporate offices will remain in Stamford. “We are pleased to announce the highly synergistic combination of the TiO2 businesses of Tronox and Cristal that will

bring significant value to our shareholders, our customers and our employees,” said Casey. “Our intent to sell alkali comes at an attractive time as the global market for natural soda ash is recovering and prices are improving,” added Casey. “This agreement will create the most diverse manufacturing platform of any titanium dioxide company. The resulting global network and synergies arising from the consolidation of businesses will allow us to better meet customer needs worldwide and provide a more sustainable business,” said Dr Talal Al-Shair, vice chairman, Tasnee and chairman of Cristal.

CRODA TO EXPAND POLYMER CAPACITY IN UK; INVESTS £27 MILLION

roda International Plc has invested £27 million in expanding its Hull manufacturing site in the UK, which will nearly double existing capacity. The £27 million ($33.52 million) investment is in line with the group’s strategy of investing in faster growth markets. It will enable Croda to satisfy growing demand for its renowned polymer additives through to 2030 and beyond. The Hull site is one of three polymer additive manufacturing plants in Croda, with the others located in Gouda, Netherlands and Mianyang, China. The plants produce fatty acid amides and innovative slip additives including Incroslip SL, the ultimate in high slip and stability. This investment further strengthens Croda’s commitment to the global polymer market and enhances its position as the market leader in this technology.

“Croda is committed to offering the highest quality products delivered with world class service. This significant investment at our Hull manufacturing facility will allow us to meet our customers’ increasing demands in a growing market and to further develop our innovation pipeline,” said Mike Millington, global managing director polymer additives, Croda.

Croda’s Hull manufacturing site in UK.

“This strategic investment highlights Croda’s commitment to UK manufacturing and provides job security for our local workforce. Our increased capacity will combine cutting edge technology with optimised production and process efficiencies to ensure that we continue to supply the highest performing and most innovative products possible,” said Carl Evans, Hull site director at Croda.

COVESTRO SELLS SPRAY POLYURETHANE FOAM BUSINESS TO ACCELLA

ccella Polyurethane Systems LLC plans to acquire certain assets of the North American spray polyurethane foam (SPF) business located in Spring, TX, from Covestro LLC, for an undisclosed amount. The sale is scheduled to be completed in the second quarter of 2017. “This acquisition will significantly improve Accella’s position in the spray polyurethane foam market and is another strategic step with our positive track record combining the best polyurethane based companies in

Chemical Today Magazine | March 2017

the industry,” said Andy Harris, president and CEO, Accella. Chris Brink, Accella’s VP of polyurethane systems, added “SPF is a very important area of business for our company with the value it brings to society. We will continue to raise the position of SPF as the preferred insulation choice in modern residential and commercial construction.”

leading producer of spray polyurethane foam, which is used as insulation and roofing in the construction of commercial buildings and residential homes.

The Covestro Spring, TX facility includes both commercial and production operations, serving North America as a

This divestiture will allow us to focus on our core business,” said Jerry MacCleary, president, Covestro LLC.

“Both technically and commercially, Covestro’s SPF team have helped grow spray polyurethane foam as a technology in the construction market.

WACKER EXPANDS POLYMERIC BINDERS CAPACITY IN GERMANY

acker Chemie AG is expanding its existing production plants for polymeric binders in Germany. The company is currently building another dispersion reactor with an annual capacity of 60,000 metric tonnes at its Burghausen site. Some €25 million have been reserved for the production and local infrastructure expansion. The plant is scheduled for completion before the end of the year. Wacker’s dispersions are commonly used to formulate low-odour and low-emission indoor paints, but can also be found in plasters, adhesives, carpet applications or technical textiles. Moreover, they are the key raw material for the production of dispersible polymer powders for construction applications. This way, Wacker is taking account of the globally rising demand for high-quality

polymeric binders, which is being driven by worldwide trends such as urbanisation, renovation and energy efficiency. Alongside the new reactor, the group is also investing in the expansion and modernization of local infrastructure. “The additional capacity will strengthen our market position as one of the world’s leading manufacturers of dispersions and dispersible polymer powders, and will help us meet our customers’ continuously increasing demand over the long term,” said Rudolf Staudigl, president & CEO of Wacker. “We are not only making a key contribution to supply security in the years to come, but also to the cost-efficient production of our dispersions and dispersible polymer powders,” said Peter Summo, head of the Wacker Polymers business division.

MITSUI CHEMICALS ACQUIRES 10 PC STAKE IN BELCHIM CROP PROTECTION

itsui Chemicals Agro Inc (MCAG) said that it has acquired 10 percent stake in Belchim Crop Protection NV, a Belgium based agrochemicals company. In a company press release, Mitsui Chemicals said, “MCAG has built a mutual trust with Belchim presently through the distribution of MCAG’s products. With taking advantage of both companies’ strengths, this business and shareholding will enable MCAG to reinforce the relationship with Belchim and drive further success by accelerating development of the market as well as new products in European market.” “It is a privilege to join forces with a strong R&D partner like Mitsui Chemicals Agro, so we can amplify our existing innovative portfolio and make our company future proof,” said Dirk Putteman, CEO, Belchim Crop Protection NV.

Mitsui Chemicals Agro Inc (MCAG) has acquired a 10 percent shareholding position in Belchim Crop Protection NV. The two companies agreed on a business collaboration. This collaboration and shareholding will reinforce the relationship with MCAG and drive further success for both companies by accelerating the development of products in the market as well as introducing new products into the market.

Chemical Today Magazine | March 2017

“Belchim has the regulatory know-how and a strong market access in Europe. With Belchim as a partner, we will enhance our overseas business and strengthen MCAG’s sales considerably,” said Kazunori Tani, president, Mitsui Chemicals Agro. Founded in 1987, Belchim Crop Protection NV is a globally expanding company with sales of €460 million in 2016.

NEWS MAKE A DIFFERENCE AKZONOBEL ADDS COLOURFUL SPARKLE TO THE

NEW MCLAREN-HONDA FORMULA 1 CAR

he 2017 McLaren-Honda Formula 1 racing car was launched, when fans caught their first glimpse of the MCL32’s new Tarocco Orange livery - a colour developed by AkzoNobel in conjunction with McLaren-Honda. The company’s colour expertise has enabled the world championship winning Formula 1 team to maintain links to their 1960s roots and heritage, while bringing a new image and sparkle. The new Tarocco Orange colour provided a striking contrast to matt black and gloss white finish when the new car was launched at the McLaren Thought Leadership Centre, in Woking, UK.

12 6

Chemical Today Magazine | March 2017

“We share a passion with McLaren for creating efficient, high performance technology. McLaren-Honda Formula 1 team is known for their iconic livery and the new colour will add a new chapter to this, which we are proud to be part of,” said Peter Tomlinson, managing director of AkzoNobel’s vehicle refinishes business. The two companies have been working closely together since 2008, when AkzoNobel first became official supplier of paint solutions to the McLaren-Honda Formula 1 team. McLaren-Honda will use the company’s premium Sikkens brand for its Formula 1 cars for the whole of the 2017 season, which starts in Melbourne,

Australia, on March 26. “With the McLaren-Honda MCL32, we’re really leveraging AkzoNobel’s colour expertise and technology. The results are stunning,” said Jonathan Neale, COO, McLaren Technology Group.“We’ve also made significant progress in reducing the average curing time of bodywork parts by more than half, and lowering the paint shop’s carbon footprint by up to 80 percent. We will continue working with AkzoNobel on further innovations as we investigate coating possibilities, both for now and for the future,” he added. The 2017 MCL32 will be driven by Fernando Alonso and Stoffel Vandoorne

One of the many archers who have enjoyed great success with Beiter nocks is Lisa Unruh of Germany, who recently was named a 2016 Woman Athlete of the Year by the World Archery Federation.

COVESTRO POLYCARBONATE USED

TO MAKE PRECISION NOCKS FOR ARCHERS A

rchery is a sport that’s all about precision, which is why bow and arrow technology is continuously evolving. That also applies to the nock of an arrow – the notched tip that briefly clasps the bowstring before the tension of the drawn bow is released and the arrow takes flight. It’s the central point where tremendous energy is directly transferred to the arrow, enabling it to reach speeds of over 300 kilometres per hour. Werner Beiter GmbH & Co KG, located in the town of Dauchingen in Germany’s Swabia region, is considered a pioneer in precision injection moulding and has gained an international reputation

Chemical Today Magazine | March 2017

as a manufacturer of premium archery accessories and parts. Since 1985, the company has been using the polycarbonate Makrolon® 2805 from Covestro for its nocks. With its mechanical strength – and effective colours developed for this area of application – the polycarbonate is the key to the nocks’ outstanding quality. The international renown of these products is ultimately due to their remarkable durability, coupled with a visual effect that enables an archer to see the arrow’s point of impact, even from considerable distances. One of the many archers who have enjoyed great success with Beiter nocks is Lisa

Unruh of Germany, who recently was named a 2016 Woman Athlete of the Year by the World Archery Federation. National teams, world champions and Olympic medalists from all over the world are constantly flocking to the Werner and Iris Centre at Beiter’s site in Dauchingen – an incomparable facility for testing archery equipment. They’re always on a quest for the latest refinement that can push the boundaries of world-class performance a little further. And Makrolon® 2805 is always in the forefront whenever successful archers celebrate their victories, the company said.

NEWS MAKE A DIFFERENCE CHANDRA ASRI SUPPLIES POLYPROPYLENE RESINS FOR TOYOTA

olypropylene impact copolymer resins which are produced by PT Chandra Asri Petrochemical Tbk, Indonesia’s largest integrated petrochemical company, meets the specifications defined by PT Toyota Motor Manufacturing Indonesia (TMMIN) to be used as raw material for the manufacturing of car components for Toyota Vios and Yaris. This success is a major breakthrough for Indonesian petrochemical industry in entering the automotive component sector that applies international standards, which have been supplied by other countries. In addition to a new marketing field that will continue to increase along with the development of the automotive industry, this breakthrough will support efforts of the Indonesia government. The government is looking to strengthen the

national industrial structure because this is a mutually beneficial cooperation between the company and TMMIN. It also improves the performance of compounding and moulding industry in the country, namely PT Hexa Indonesia who adds additives and colouring in resins and PT Sugity who mould the resins into automotive components. Besides Toyota Vios and Yaris, the company also plans to supply the models for Fortuner and Kijang Innova as well as other cars of LCGC Toyota. Currently, other brands, which have used the company’s polypropylene impact copolymer are LCGC Daihatsu and Honda cars and motorcycles. Further, the import substitution for these resins and car components can save the country’s foreign exchange.

METAMATERIAL TECHNOLOGIES, AIRBUS TO DEVELOP LASER PROTECTION PRODUCT METAAIR™

George Palikaras, founder and CEO of MTI, demonstrates how Bayfol HX photopolymer films from Covestro block and deflect the light of high power laser pointers.

etamaterial Technologies Inc (MTI) and its optical filters division, Lamda Guard has agreed with leading aircraft manufacturer Airbus to validate, certify, and commercialize its laser protection product metaAIR™, for aviation. In 2014, MTI signed its first agreement with Airbus to test and tailor metaAIR™, which is a flexible metamaterial optical filter, engineered to protect vision against harmful laser beams aimed at aircraft. Laser strikes on commercial aircraft are rising globally. In 2015, according to the Federal Aviation Administration (FAA), the number of reported laser incidents nearly doubled to 7,703 in commercial aviation. “We also see an increasing number of possible applications for metaAIR, beyond the commercial aircraft division,” said

Chemical Today Magazine | March 2017

Pascal Andrei, vice president, chief product security officer, Airbus Group. MTI is a great example of Airbus “start-up 2 partner” programme led by Elsa Keita from Airbus Corporate Innovation. This programme aims at building mutually beneficial partnerships with disruptive innovators. “Our objective is to place Canada and its citizens on innovation’s leading edge,” said Navdeep Bains, Canadian minister for innovation, science and economic development and minister responsible for the Atlantic Canada Opportunities Agency. “We look forward to continuing our relationship with Airbus as we move to commercialize metaAIR. Together we will be able to make a positive impact on the aviation industry around the world,” said Maurice Guitton, MTI board chairman.

“metaAIR will provide vision protection to pilots in the aviation industry and can offer solutions in other industries including the military, transportation and glass manufacturers,” said George Palikaras, MTI Founder and CEO. MTI has also developed a partnership with Covestro, which supplies a custom Bayfol® HX photopolymer film for the manufacturing of metaAIR™. “MTI is at the cutting edge of optical applications. They have developed a unique optical filter that is different from anything currently available on the market. We have been working with them for the last two years to provide a speciality photopolymer material film and support the required volume,” said Thomas Facke, responsible for marketing and business development of photopolymer films at Covestro.

AKZONOBEL, BARRIER, DRONEOPS TO DEVELOP DRONE TECHNOLOGY FOR MARINE INDUSTRY

kzoNobel NV, oil and gas tank operator Barrier Group and DroneOps joined forces to develop a drone capable of remotely inspecting enclosed spaces and ballast water tanks, thus improving the safety in the marine industry. The project will use advanced virtual reality technology to deliver safer, more accurate evaluations of ballast water tanks, offshore wind farms and other enclosed or difficult to access spaces on ships and marine structures, including inspections of coatings and corrosion. Usually, inspections are carried out by a crew, surveyors or independent inspectors – a potentially risky activity which represents one of the most common causes of workrelated fatalities in the industry. By replacing human inspections with a drone, routine maintenance can be monitored remotely and in real time by office-based staff, with instant feedback available to the vessel or offshore structure’s superintendent. The partnership itself offers a complete overview of the issues and challenges associated with enclosed space inspections. Additional coatings expertise will be provided by Safinah Ltd, a leading coatings consultancy. AkzoNobel is already using innovative drone technology. The company is currently testing the use of drones in Australia for inspecting sites in remote locations where access is limited and the movement of heavy equipment is difficult. As the new project progresses, the drone will undergo flight trials at AkzoNobel’s UK-based coatings test site and Barrier Group’s indoor training facility. The drone’s completion and launch are planned for October 2017. “Surveys of enclosed spaces and ballast water tanks are an essential part of routine maintenance and are increasingly critical for ship owners,” explained Michael Hindmarsh, business development manager at AkzoNobel’s marine coatings business. “Inspecting these areas thoroughly can require working at height, entering confined spaces and negotiating slippery surfaces that could be poorly lit, all of which are high-risk activities that the maritime industry is keen to address,” he concluded

Chemical Today Magazine | March 2017

TIO2 PRICE RECOVERY TO CONTINUE A

more balanced global supply outlook, stable end-market demand and expected producer pricing discipline should enable prices for titanium dioxide (TiO2) to continue to rise throughout 2017 and into 2018, according to Fitch Ratings. Continued TiO2 pricing momentum should also lead to stronger TiO2 feedstock prices over the medium term, although Fitch does not expect significant recovery in the short term given a general lag in recovery of the feedstock market relative to the pigment industry. Stronger cash flow generation from higher prices and restructuring initiatives should help US producers repair balance sheets that have been hampered by the pressured conditions of the past several years. Global supply is currently more balanced due to notable closures over the past two years that have helped thin the global supply glut. Fitch expects these closures, which represent 270,000 tonnes of capacity, and the recent fire at Huntsman’s sulphate plant in Pori, Finland, will lead to tighter supply in the near term. This should lead to more balanced market conditions that enable global demand to better catch up to global supply. Fitch believes top Western producers are strongly incentivized to adopt a more disciplined pricing strategy to offset earnings exposure to the pigment

Chemical Today Magazine | March 2017

industry. Huntsman’s decision to spin off its pigments business to Venator Materials Corp. means that, by mid-2017, two of the three largest TiO2 producers in the world will operate as stand-alone entities. These producers were previously business segments of larger conglomerates whose consolidated earnings were less sensitive to TiO2 price volatility. Utilization rates are projected to increase to the upper 80 percent range by 2018 from the low 80 percent range in 2015, driven by tighter supply and recovering demand that should largely track GDP after years of sub-GDP growth. The agency believes the downward demand pressures of high customer inventories and paint reformulation by top coatings companies that led to a weaker demand profile in the past have largely abated. However, the TiO2 industry as a whole will still be highly sensitive to historical stocking and destocking trends. Additionally, the supply reductions of the past two years should be offset in the long term as Chemours’ Altamira expansion ramps up to full capacity, emphasizing the importance of stable demand growth and producer pricing discipline in Fitch’s projected recovery. Fitch expects prices for both sulphate and chloride TiO2 feedstock to eventually follow pigment prices directionally, given

that around 90 percent of TiO2 feedstock produced is used for pigment production and projects the feedstock market will recover in the medium term. However, recovery will likely be modest in the short term, owing in part to what Fitch understands to be a general sixto nine-month lag between realizing a price recovery in TiO2 and that recovery beginning to flow back downstream to feedstock producers. The credit profiles of US producers such as Chemours, Kronos Tronox have improved throughout 2016 and should continue to strengthen in 2017. Higher prices and restructuring initiatives have led to an influx of cash that has enabled issuers to replenish liquidity and deleverage balance sheets, which are currently elevated due to depressed pricing, and, in some cases, high debt loads as a result of acquisitions. However, liquidity, financial leverage and capital allocation strategies separate the directional momentum of issuer credit profiles. Chemours’ b+*/positive* credit opinion rating benefits from high liquidity, projected deleveraging and the resolution of certain legacy liabilities inherited from its spinoff from DuPont; conversely, Tronox’s b+*/negative* credit opinion rating stems from high leverage and a tendency to pursue more shareholder-friendly actions at the expense of its balance sheet.

EVENTS 01 – 03 March 2017

UPCOMING EVENTS

FSHOW 2017

Chemical Today Magazine | March 2017

Location: Shanghai new international expo centre, China Organised by: CCPIT Sub-Council of Chemical Industry Website: http://www.worldofchemicals.com/media/event/fshow-2017/374.html FSHOW is the fertiliser branch of China International Agrochemical & Crop Protection Exhibition (CAC) from 2010. During FSHOW, many fertiliser enterprises have seized the chance to show their strength of enterprises with FSHOW platform.

08-10 March 2017 CPhI Istanbul 2017

Location: Istanbul Expo Center (IFM), Istanbul – Turkey Organised by: UBM plc Website: http://www.worldofchemicals.com/media/event/cphi-istanbul-2017/357.html This event brings together local Turkish and regional drug manufacturers with global suppliers of raw materials, machinery, packaging solutions and contract services.

20 – 23 March 2017 Arablab 2017

Location: Dubai International Convention & Exhibition Centre, Dubai, UAE Organised by: ARABLAB Group Website: http://www.worldofchemicals.com/media/event/arablab-2017/355.html Arablab is the only trade show for the Analytical Industry that reaches buyers from the growth markets such as the Middle East & Africa and the Indian SubContinent as well as China & Asia.

28 – 30 March 2017 LogiChem 2017

Location: Movenpick Hotel, Amsterdam, Netherlands Organised by: Worldwide Business Research Website: http://www.worldofchemicals.com/media/event/logichem-2017/369.html LogiChem is the must attend event for heads of supply chain and logistics from the world’s leading chemicals manufacturers as they look to achieve commercial and supply chain excellence. LogiChem is the only dedicated “supply chain as a business enabler” conference in Europe and the only place to access 200+ chemical supply chain leaders in one place at one time.

08 – 11 July 2017 Plastasia 2017

Location: Pragati Maidan, New Delhi Organised by: Triune Exhibitors Pvt Ltd Website: http://www.plastasia.in/ The 6th Plastasia 2017 event brings together key industry players and decisionmakers from the corporate and public sectors in the region providing a strategic setting to forge business tie-ups and contacts. The event showcases the latest technology and machineries used in manufacturing of plastics and petrochemicals with participation from different parts of the world.

07 – 08 March 2017 AMAI 2017

Location: Surya Palace Hotel, Vadodara. Organised by: AMAI Website: www.ama-india.org International Conference on development of chloro chemicals in India in association with CCAIA & CCAON, China brings together chlorine manufacturers, existing and prospective chlorine consumers as well as prospective investors, technology licensors for chloro chemicals from India and China, designers & suppliers of plant & equipment for chloro chemicals plants from India & China, detailed engineering consultants, Chinese chloro chemicals manufacturers.

21 – 22 March 2017 CAPINDIA

Location: Bombay Exhibition Centre, Goregaon, Mumbai Organised by: Chemexcil, Capexcil, Plexconcil, Shefexcil. Website: http://capindia.org.in/ CAPINDIA brings together domestic & Overseas buyers, International Agents and Distributors seeking market representation from Indian exporters, End Users seeking raw materials for captive consumption, Private Label Buyers, Merchant Exporters, Industrial and Marketing Consultants, Central and State Government Departments & Agencies to showcase a range of Industrial & Agricultural Raw Materials, Consumer Items, Packaging Items, Plastics Processing Machinery and Construction Raw Materials.

12 – 14 April 2017 China INTERDYE 2017

Location:CHINA Shanghai World Expo Exhibition & Convention Center (SWEECC), Shanghai, China Website : http://www.chinainterdye.com/en/ China INTERDYE is a UFI approved exhibition. It will be a stand where plenty of crucial goods will probably be presented. Several of these are generally dye, textile chemicals and printing industry. This event showcases products like pre-treatment auxiliaries, dyeing auxiliaries, finishing auxiliaries, printing auxiliaries, acid dyes, azoic dyes, basic dyes, direct dyes, disperse dyes, mordant dyes, reactive dyes, sulphur dyes, vat dyes, etc. in the chemicals & dyes, textile, fabrics & yarns industries. It is a place where buyer-seller meets and get-together and a platform for new partnership developments.

04 – 05 March 2017 AZEOTROPY 2017

Location: IIT Bombay, Mumbai, India Organised by: IIT Bombay Website: http://www.azeotropy.com/ AZeotropy is organised by students of IIT Bombay in the month of March. We aim to emphasize the spirit of engineering, experimenting with ideas and learning from them. Every year more than 4000 students from over 350 colleges come and participate in our competitions, lectures & workshops. Also more than 100 corporate personalities from industry as well as academia attend the symposium. We have also seen personalities such as Dr Rakesh Agrawal (Distinguished Professor, Purdue University), Mr. Harsha Bhogle (Indian cricket commentator, Journalist and a Chemical Engineer), Dr K Vijay Raghavan (Secretary, Department of Biotechnology, India and Distinguished Professor and former Director of The National Centre for Biological Sciences), Mr. Achyut Godbole (Managing Director of Syntel India) and many others being a part of AZeotropy.

Chemical Today Magazine | March 2017

EXPERT VIEWPOINT SURFACTANTS

BRINGING THE

‘NATURALNESS’ IN SURFACTANTS BY DEBARATI DAS Key growth drivers for consumer based surfactants market. Some of the growth drivers in this market will be: • Increasing significance of youthful appearance • Skin intolerance and allergies occurring more often • Growing concern about harmful effect of artificial substances • Greater desire for natural but effective products • Sustainable production and environmental compatibility increasingly desired in cosmetics as well • Market for natural cosmetics growing rapidly

and

organic

• Purchasing power of consumer has increased – consumers are willing to pay a premium for sustainable products

Global product manufacturers’ demands and expectations. For surfactants – an important group of ingredients of personal care products is the trend towards greater ‘naturalness’. The large group of surfactants based on renewable resources is preferred over petroleum-based surfactants.

R Kumaresan, Head, Business Unit, Industrial and Consumer Specialties, India, Clariant, opens up about the shift in consumer preferences towards natural and organic cosmetics, which has made the consumer based surfactants industry rethink about its chemical compositions.

Chemical Today Magazine | March 2017

Also, efficacy or effectiveness is the most important key driver, although there is considerable attention to certain toxicological parameters. Mildness is another important feature demanded for hair and skin cleansing products. This is now also extended to other skin-contact products like dishwashes and fabric washes. Lastly, the trend to switch from traditional bar soaps to liquid gels and soaps, is also creating more demand for surfactants.

Implementing sustainability in the company. Sustainability is intrinsic to our strategy. Recently, we launched a 5-year multipartner project for a sustainable supply chain with L’Oreal addressing

social, environmental and economic improvements. We also RSPO-certified (mass balance) our plants for sustainable palm oil supply. Other examples include achieving Halal certification at certain plants and the commitment of APEO-free surfactants for the Coating markets. Innovation and sustainability will definitely make the difference in retaining our leadership position.

Focus on R&D and innovation for surfactants. For personal care: Clariant has launched GlucoTainTM, which is an innovative range of sugar-based surfactants offering sensory benefits through individual foam structures – from fluffy to rich – and light to caring conditioning levels. It creates new possibilities for formulators to go the next step in developing innovative products and platforms based on sulfate-free, CAPB-free and betainefree formulations for a wide range of applications. In addition it addresses the consumer’s desire for more natural and mild products with no compromise on cleansing properties. GlucoTainTM is suitable for hair care and skin care applications such as shampoo, shower liquid, soaps, facial cleansers or shaving foams. Its EO-free and sulfate-free ingredients are readily biodegradable products with a 94-95 percent RCI (Renewable Carbon Index), a high content of non-tropical biomass, and a good ecotox profile.

Chemical Today Magazine | March 2017

Industrial and consumer surfactants business of the company. Clariant focuses on increasing the efficiency of surfactant systems in cleaning formulations as this addresses a key aspect of sustainability. Our ongoing search for sustainable solutions led us to GlucoPure™: innovative and highperforming sugar-based surfactants for hand dishwashing and hard surface cleaners. GlucoPure™ is based on sugar and natural oils such as RSPO certified palm oil resulting in a Renewable Carbon Index of up to 95 percent. From specific blends to facilitate and accelerate the production of many different formulations from our customers, to synergy concepts based on the versatile and powerful perfomanceboosting ammonium quaternary PraepagenTM HY. Our range allows formulations even with anionic surfactants, and enables a reduction in the total amount of surfactants used. GenaminoxTM CHE is a new amine oxide in the Clariant line of products, allowing much more efficient and environmentally friendly formulations for cleaners and disinfectants formulations. Clariant offers a complete portfolio of surfactants including: Anionics | Ethoxylates | Amine Oxides | Betaines | Quats / Esters | Amine derivatives | Sugar surfactants

EXPERT VIEWPOINT FOOD & BEVERAGE ENZYMES

ADDING ENZYMES

FOR BETTER NUTRITION

Andrew Fordyce,

Executive Vice President, Food & Beverages, Novozymes A/S talks at length about the ways in which enzymes can make food and beverages healthier, tastier and nutritious.

14 22

Chemical Today Magazine | March February 2017 2017

BY SHIVANI MODY Trends in the food & beverage enzymes industry.

Areas of growth for food & beverage enzymes.

make for slower ramp-up of new products, but long lifetime.

Food & beverage enzymes are the largest category in the enzyme world – yet only a small fraction of the food ingredients and processing aids market. It is a global industry with many applications – beverages, baking, starch, oils & fats, and food & nutrition.

We see demand for our enzymes that supports the global trends of urbanization – which for instance means more on-the-go eating.

Potential regions for growth.

Novozymes is the global leader in the food & beverages enzyme market. It is the most fragmented and diverse market for the company – with a broad portfolio of 300+ products across applications. We help customers improve the quality and sustainability of their food and beverage products and the processes and thereby bring better products to consumers.

In terms of regions, from the ongoing industrialization of emerging markets – Latin America, the Middle East and Africa, China, India, and Southeast Asia – is where we will see increased growth.

We have identified two macro trends and three industry trends that also set the scope for future growth. Around the world we are witnessing shifting demographics and urbanization. This creates a growing demand for better, more convenient and healthier foods, for improved processing and optimization of raw materials, and also for substitutes for animal protein, all areas where enzymes can help. This trend also creates challenges, as consumers form preferences for traditional foods, and local markets and dietary habits are fragmented. Local market regulation is also fragmented and this slows market entry. Another macro trend is the digitalization of the global economy. Our customers use data analytics to validate the efficiency gains they achieve by using enzymes. In the food & beverages industry, consumers focus more on health, wellness and natural products. This translates into business opportunities for enzymes, as we witness an increased awareness about food safety, a demand for “naturally healthy” products, and growth in the market for “food intolerance” products, such as lactose-free dairy. Another strong trend in the industry is the increased cost of raw materials. This increases demand for optimization in raw materials and production processes. Finally, we see customers consolidating operations, but diversifying brands to cater to hyper local consumer preferences. This provides an opportunity for Novozymes to forge strong partnerships with our customers and help them optimize costs and build their brands.

Chemical Today Magazine | March 2017

We all see the rise of organic, where enzymes can support the labeling of our customers’ products.

There is also an interesting growth area in terms of enabling the use of local raw materials eg. brewing in Africa where there is a strong culture of homemade beer – opaque beer – made out of locally grown raw materials like sorghum or cassava. In cases like this, we are extremely proud when our enzymes are used to ensure consistency and make commercial beer based 100 percent on such local raw materials, helping to produce high-quality local offerings, while catering to the traditional taste of the consumers.

Technological development in food & beverage enzymes business. The company invests around 13 percent of our revenue back into R&D to help us to find new and effective enzyme and microbial solutions for our customers. With that industry-leading investment we continue to find new enzymes that expand our ability to transform the quality and sustainability of our customer’s food and beverage products and processes. Examples of our innovation are our recent launch of Extenda brand products for starch refining, new enzymes launching in 2017 for oil and fats processing, and our newest enzyme for dairy, a lactose-reduction product called Saphera. We see this commitment to innovation as a powerful way for us to help the Food and Beverage industry to take advantage of opportunities and improve business.

Factors restraining increased usage of food & beverage enzymes. I can mention two factors – an increased focus on costs at our customers, and then the very fragmented nature of the food & beverage industry. A lot of the needs are niche, which means we cannot justify innovation in all areas. The fragmented industry structure and industry profile also

The more established markets – Europe and North America – are the largest markets for Novozymes food & beverage today. However, we definitely see the rise of the emerging markets, and we expect and plan for a balancing out of the global picture. However, it is very different by sub-business. We are seeing growth potential in literally every emerging market – including China, India, Southeast Asia, Latin America, and certain Middle Eastern and African countries.

Food & beverage enzymes business within the company. We are the second largest business area for Novozymes and serve several key markets, including: • Baking •

Starch processing

•

Oil seed processing

•

Dairy and infant formula

•

Beer, wine & distilled alcohol

•

Juice production

Plans to expand footprint in potential regions. The ongoing industrialization and urbanization of emerging markets in AsiaPacific, Middle East, and Africa regions continue to provide growth opportunities for our biological solutions. Our strategic plan is to invest in regional footprints and sharper techno-commercial capabilities to better understand customers’ needs – and develop solutions that address their needs. Another key part of our strategic plan is to drive regional innovations, particularly relating to locally available raw materials, and to develop new enzymatic applications in indigenous foods and beverages.

Latest R&D and innovations. Some of our recent examples in R&D: • Saphera: a lactase enzyme that sets a new standard for production and quality of a wide range of lactose-free products, including milk and fermented dairy products such as yogurt. Originated from Bifidobacterium bifidum, Saphera differs considerably from traditional lactases made from yeast. With Saphera, the desired lactose level can be more precisely measured and easily reached. Saphera

Low-allergenic infant food.

works at lower pH and higher temperature than other lactases and is therefore not only suitable for production of lactose-free milk and other products, but also for fermented dairy products. • Extenda: an enzyme solution that lowers the cost of converting starch into sweeteners. Targeting the saccharification step, the enzyme produces more dextrose than any other product in the market. • Acrylaway: modifies the amino acid asparagine which is responsible for the formation of acrylamide during cooking. This significantly reduces the level of acrylamide in the final food product. Acrylamide is a chemical compound naturally formed in some food types when baked, fried, toasted or roasted and is considered to be a potential health risk.

Enzymatic degumming

Quality and sustainability of food & beverages enzymes by the company. A few examples to explain Novozymes’ work towards quality and sustainability: Novamyl is an enzyme that keeps bread fresh longer. It reduces the amount of waste while still allowing for very high quality bread. The bread remains softer and more resilient for longer, reducing unit costs and number of deliveries required to keep fresh products on the shelf. With our newest innovations in starch we help our customers get more starch and more protein with less corn; we help them process starch at lower pH levels while using less water. We help our customers sustainably convert oil feedstocks into biodiesel whilst lowering the use of chemicals. Novozymes’ solutions help juice producers ‘make more from less’ by squeezing more juice out of apples, pears, stone fruits,

Brewing with enzymes

Chemical Today Magazine | March 2017

grapes, and berries, as well as removing haze-causing substances from the juice. Enzymatic interesterification produces hard stocks for margarine and shortening fats without creating unhealthy trans-fatty acids. Enzymatic interesterification is a more cost-efficient process than chemical interesterification. And with Saphera we enable dairy producers to easily reach the desired lactose level in low-lactose products.

Factors that will increase demand for Carbohydrases usage. Carbohydrases is one class of enzymes that is used actively in food & beverages, along with proteases, lipases, and cellulases. We see growth in all of the enzymatic categories due to increasing volume of food processing and innovation that increases the benefits of enzymes for food & beverage processers.

Ways you address consumer awareness towards food quality, safety, processed & packaged food and waste reduction.

• Our strategies are linked to the mega trends that I mentioned before. For instance, in the area of safety we have a technology, Acrylaway, that can significantly eliminate acrylamide in fried foods. • We work with regulatory agencies to ensure that Novozymes enzymes are fully compliant with all requirements to be sold ie. FIAP registrations. • We are exploring technologies that can improve yields in vegetable oil processing. • We look for different substrates ie. cassava, to apply enzymes, or to use local raw materials in such areas as brewing. • As market leader it is our job to increase the penetration of enzymes – not merely try and take market share from our competition. • That is also why we spend around 13 percent of sales on R&D to ensure that we can continue to supply our customers with new exciting innovation and remain the global leader in enzyme technology.

EXPERT VIEWPOINT CONSTRUCTION CHEMICALS

SUSTAINABLE ARCHITECTURE

IS THE FUTURE

Sanjay Bahadur, Chief Executive Officer, Pidilite Industries Ltd delves into the reasons how waterproofing chemicals is one of the most important segments in construction activities. Yet in India, this market is at a premature state due to the use of traditional methods of construction. He also talks about how Pidilite is working towards raising the awareness in the Indian construction business on carrying out effective waterproofing. 26

Chemical Today Magazine | March 2017

BY DEBARATI DAS Construction chemicals industry in India. Indian construction chemicals market is still at a growing stage as usage levels are much lower compared to other markets due to limited awareness about products and their benefits as well as price conscious customers. Although at a nascent stage, the Indian construction chemical market will exhibit a CAGR of 17.2 per cent during 2016 to 2020 and expected to reach $1.89 billion by 2020. The consumption of construction chemicals is also set to increase alongside robust growth in the cement and construction industries. Construction chemicals provide buildings and structures with many enhancing properties such as higher strength, more longevity, reduced water requirement, and also increased resistance to abrasion and corrosion. Once, more number of people realize the benefits that can be obtained from utilizing construction chemicals, the market will witness further expansion.

Trends and latest development in waterproofing chemicals. Green construction is the current trend in construction chemicals and waterproofing solutions market in the country. The waterproofing market in India is at a very

premature state, since the bulk of the construction sites use traditional methods like brickbat coba and mud puska, which have their own limitations. Hence, we see this as an area where huge opportunities exist. There is an urgency to inculcate the right material usage, right dosage and the correct application to ensure that we create healthy structures. As far as development in the construction chemicals industry goes, it has huge growth potential due to the construction and manufacturing boom in India. Many newly developed products give better performance and results - hence there will be a shift in demand towards products offering better performance.

Key market drivers supporting growth of waterproofing chemicals. Although it is said that the construction chemicals’ industry has a good growth potential over the next few years, the industry needs continuous support from the government, regulatory bodies as well as the industry associations / federations to sustain its growth. Some of the key growth imperatives seen for the construction chemicals industry in the year ahead include strong marketing strategies and increased customer awareness towards applications and benefits.

The growth of construction chemicals and waterproofing segments are strongly linked to construction and infrastructure industry nationwide. The mammoth $1 trillion infrastructure investment during 12th plan period, the government’s ‘Housing for All by 2022’ target and the upcoming 100 Smart Cities project will be the main drivers for the construction chemicals and water proofing industry. The waterproofing market nationwide is at a growing stage, since the bulk of the construction sites are still stuck with traditional.

Government initiatives to aid growth of waterproofing chemicals sector. The Indian construction chemical market is attracting lots of attention with most of the global construction companies present with their full portfolio of products in India. Increased focus on infrastructure investment by the government, vertical growth in metros, participation of overseas investors and contracting companies, and governments’ plan to build 100 smart cities in India will propel the construction chemicals segment in the coming years. Significant presence of global construction chemical companies in the Indian markets have further intensified the competition and boosted the market growth.

Chemical Today Magazine | March 2017

EXPERT VIEWPOINT CONSTRUCTION CHEMICALS

Global customer demands in the construction industry.

the structure strong over a longer period of time.

Across India, the rapidly rising urbanization situation has ensured swift increase in the speed of construction. The construction materials and techniques, which need to be utilized has to be in sync with future challenges. Technological advancement and optimum usage of materials is vital for structures to last for many more years.

Emphasis on R&D and innovation.

However, there is an urgent need to have standards and codes, which can match the requirements of today’s construction activities. Although, few such norms exists they are outdated or inadequate. Moreover, such codes could be sourced from international standards that may not be relevant to Indian conditions. Therefore, we have to look at modifying these standards and bringing them in line with the local Indian conditions.

Focusing on sustainability for your products and processes. With an increase in awareness levels among general masses, the demand for sustainable architecture is set to increase. Coinciding with the simultaneous bursting of the real estate bubble in many countries, sustainable architecture has gone from being marginalized to emerging as an increasingly vital part of any type of project. A similar trend is expected to be followed in India as well in the coming years. With buildings moving from conventional approach to energy and water saving structures, our built environments will have less impact on the natural surroundings. The future is headed in the direction where every structure being built adheres to specific sustainability and ‘green’ norms. Dr Fixit LEC (Low Energy Consumption) and Dr Fixit Blue Seal are the two most effective innovations for sustainable construction from the house of Pidilite. These products enhance the lifecycle of the building providing better insulation and reducing heat. This in turn also reduces the overall energy consumption and hence the carbon footprint of the building. Additionally, unlike other conventional raw materials, these products help in reducing the thermal stress on a structure and eliminate leakages that result in expansion of the steel used in the core of the walls and pillars. Hence, it can safely be said that these products help in keeping

Chemical Today Magazine | March 2017

State of the art technology with global competition mapping leads the R&D to develop the best in kind products. Also while doing this the marketing practices are studied and well kept in mind. Our consistent efforts are to generate green solutions for various areas of application catering to the needs of complex high-rise structures. We remain committed towards creating technologies which are state-ofthe-art based on principles of innovation. Our products also aim at being environment friendly. We realise that in today’s age innovation and environment friendly solutions go hand-in-hand. Through our various products, we remain true to the needs of the environment - examples like LEC. We focus our R&D efforts to present innovative products. Our effort has also been to offer solutions and be pro-active in doing so. We understand the waterproofing industry like no other and hence bring to consumers new age solutions. We not only prescribe products but also help them with the treatment. Our best in class customer support is an example of our continuous efforts towards being customer centric. As far as our company is concerned our main focus is largely on waterproofing. Today, Dr Fixit is one of the most trusted brands in the Indian construction industry known for its innovation and pioneering solutions for waterproofing. The construction materials and techniques, which need to be utilized has to be in sync with future challenges. Technological advancement and optimum usage of materials is vital for structures to last for many more years. However, there is an urgent need to have standards and codes, which can match the requirements of today’s construction activities. Although, few such norms exists they are outdated or inadequate. At Pidilite, we offer a wide range of applications such as Waterproofing, Repair Solutions for existing structures and Tile Fixing Solutions. Also, we offer a host of other applications like Exterior Coatings, Sealants, Concrete Admixtures, Floorings and Grouts to satisfy all construction related problems. There has been a lot

of thought processes combined with uninterrupted R&D that have helped us strengthen the overall brand equity of our mother brand Dr Fixit. We offer a comprehensive range of waterproofing products that provide surface-wise solutions to satisfy diverse requirements during construction and have over the years managed to establish ourselves as a preferred brand in this category. Our products include Dr Fixit LW, Leakfree Homes, Dr Fixit Blueseal, Dr Fixit Roofseal and Raincoat Cool.

Challenges faced by construction chemicals manufacturers. The construction chemical market in India is still underdeveloped as compared to the other countries. The industry faces major challenges, which act as a hindrance in its growth. One of the biggest challenges facing the segment is low awareness about the benefits of utilizing construction chemicals. Due to low awareness, not many people realize that even though construction chemicals entail a higher initial cost, it becomes economically beneficial over the long term. The other key challenge is the practice of employing unskilled workers in construction activity. Lack of skilled workers hampers the growth of the sector, as construction chemicals are sensitive products and their use requires basic technical expertise and training. Customer service needs to be an important part of the business as it contributes towards the development of the sector. Market participants are also frequently challenged by the absence of quality standards for manufacture and applications of construction chemical, which leads to price wars. To overcome the challenges mentioned above, we have setup Dr Fixit Knowledge Centre at Kochi where we demonstrate how to carryout waterproofing properly. The Knowledge Centre imparts practical training on dealing with real life challenges in construction. The response has been very good and we are planning to open more such centers in other cities too. We have a non-for-profit organization called Dr Fixit Institute, which imparts knowledge about the best construction practices in the industry to the ACE Community and the students of civil engineering.

GREEN CHEMISTRY Breakthrough process to produce

Renewable Car Tyres From Trees and Grasses Discovery could have major impact on the multi-billion dollar tyre industry.

team of researchers, led by the University of Minnesota, has invented a new technology to produce automobile tyres from trees and grasses in a process that could shift the tyre production industry toward using renewable resources found right in our backyards. Conventional car tyres are viewed as environmentally unfriendly because they are predominately made from fossil fuels. The car tyres produced from biomass that includes trees and grasses would be identical to existing car tyres with the same chemical makeup, color, shape, and performance. The technology has been patented by the University of Minnesota and is available for licensing through the University of Minnesota Office of Technology Commercialization. The new study is published by the American Chemical Society’s ACS Catalysis, a leading journal in the chemical and catalysis sciences. Authors of the study, include researchers from the University of Minnesota, University of

Massachusetts Amherst, and the Center for Sustainable Polymers, a National Science Foundation-funded center at the University of Minnesota. “Our team created a new chemical process to make isoprene, the key molecule in car tyres, from natural products like trees, grasses, or corn,” said Paul Dauenhauer, a University of Minnesota associate professor of chemical engineering and materials science and lead researcher of the study. “This research could have a major impact on the multi-billion dollar automobile tyres industry.” “Collaboration was really the key to this research taking biomass all the way to isoprene,” said Carol Bessel, the deputy director for the chemistry division at the National Science Foundation (NSF), which funds the Center for Sustainable Polymers. Currently, isoprene is produced by thermally breaking apart molecules in petroleum that are similar to gasoline in a process called “cracking.” The isoprene is

then separated out of hundreds of products and purified. In the final step, the isoprene is reacted with itself into long chains to make a solid polymer that is the major component in car tyres. Biomass-derived isoprene has been a major initiative of tyre companies for the past decade, with most of the effort focused on fermentation technology (similar to ethanol production). However, renewable isoprene has proven a difficult molecule to generate from microbes, and efforts to make it by an entirely biological process have not been successful. Funded by NSF, researchers from the Center for Sustainable Polymers have focused on a new process that begins with sugars derived from biomass including grasses, trees and corn. They found that a three-step process is optimized when it is “hybridized,” meaning it combines biological fermentation using microbes with conventional catalytic refining that is similar to petroleum refining technology. “Economically bio-sourced isoprene has the potential to expand domestic production of car tyres by using renewable, readily available resources instead of fossil fuels,” said Frank Bates, a worldrenowned polymer expert and University of Minnesota Regents professor of chemical engineering and materials science. “This discovery could also impact many other technologically advanced rubber-based products.” In addition to Dauenhauer, researchers who were part of the study from the University of Minnesota were professors Michael Tsapatsis and Kechun Zhang, postdoctoral researchers Omar Abdelrahman, Dae Sung Park, Charles Spanjers and Limin Ren, and current student Katherine Vinter. University of Massachusetts Amherst professor Wei Fan and student Hong Je Cho were also part of the research team.

Catalytic conversion of biomass-derived chemicals to renewable polymers occurs in laboratory stirred-tank reactors. Credit: University of Minnesota

Chemical Today Magazine | March 2017

Cost-saving, longer-lasting biodegradable

Adhesive Patented

Donghai Wang, professor of biological and agricultural engineering, and Susan Sun, university distinguished professor of grain science and industry, developed a patented biodegradable resin for adhesives and coatings.

ansas State University researchers have patented the first plant-based resin of its kind that would be ideal for readherable painters’ tape, labels, packing tapes, stationery notes and other adhesive uses. It also can provide shiny coatings. “Painters generally finish projects with mounds of used tape made of low-quality paper that does not recycle,” said Susan Sun, university distinguished professor of grain science and industry and lead researcher on the project. “If they could use biodegradable tape, like ours, it would greatly reduce the amount of waste.” In addition to adhesive applications, the resin could be used in coatings on wooden surfaces, slick magazine pages, bags of potato chips and other items needing shiny and protective surfaces that are either flexible or rigid. Sun said the resin outperforms previous bio-based adhesives because it adheres to a surface for a longer period of time, has a longer shelf life and is more waterresistant. Because the substance is plantbased, its resources are biodegradable and renewable. “Our resin is unique because it is made from soybean, corn and other plant oils,” Sun said. “Currently available resins are

Chemical Today Magazine | March 2017

made from petroleum-based products, which are less sustainable, and from plant fatty acids, which cost more to process.” The research has been featured in several publications, including Biomacromolecules, Journal of Materials Chemistry and others. It has been presented at the International Material Research Conference in China, the Green Chemistry and Engineering Conference in Washington DC, the American Chemical Society National Meeting in Anaheim, California and other events. Initial funding was provided by the Kansas Soybean Commission and the United Soybean Board. Additional funding sources include the US Department of Agriculture and the National Institute of Food and Agriculture. Sun developed the resin with Donghai Wang, professor of biological and agricultural engineering and Kollbe Ahn, a 2011 Kansas State University grain science doctoral graduate who is now a research professor at the University of California, Santa Barbara. The patent was issued to the Kansas State University Research Foundation, a nonprofit corporation responsible for managing technology transfer activities at the university.

GREEN CHEMISTRY Flipping the switch on

Ammonia Production Process generates electricity instead of consuming energy.

Ross Milton works in the glove box used to keep nitrogenase in an oxygen-free environment.

provided by Minteer’s collaborators at the Instituto de Catalisis y Petroleoquimica in Spain, to strip electrons from hydrogen gas and provide them to the nitrogen-reducing reaction. The cell consists of two compartments, connected via carbon paper electrodes. In one vial, hydrogen gas is oxidized by hydrogenase and electrons are carried to the anode. In the other, electrons come off the cathode and are combined with nitrogen, via nitrogenase, to create ammonia.

early a century ago, German chemist Fritz Haber won the Nobel Prize in Chemistry for a process to generate ammonia from hydrogen and nitrogen gases. The process, still in use today, ushered in a revolution in agriculture, but now consumes around one percent of the world’s energy to achieve the high pressures and temperatures that drive the chemical reactions to produce ammonia. Now, University of Utah chemists publish a different method, using enzymes derived from nature, that generates ammonia at room temperature. As a bonus, the reaction generates a small electrical current. The method is published in Angewandte Chemie International Edition. Although chemistry and materials science and engineering professor Shelley Minteer and postdoctoral scholar Ross Milton have only been able to produce small quantities of ammonia so far, their method could lead to a less energy-intensive source of the ammonia, used worldwide as a vital fertilizer.

Chemical Today Magazine | March 2017

“It’s a spontaneous process, so rather than having to put energy in, it’s actually generating its own electricity,” Minteer said.

Simulating a cell In biology, conversion of gaseous nitrogen to ammonia is called nitrogen “fixation” and is accomplished through several pathways, including through enzymes called nitrogenases. Used by some bacteria, nitrogenases are the only known enzymes to reduce nitrogen to ammonia. Nitrogenase is rarely studied in fuel cell applications, because the enzyme is not commercially available and must be handled in an oxygen-free environment.

The electrons move from the anode to the cathode via a circuit. Protons (oxidized hydrogen atoms) travel through a membrane between the anodic and cathodic chambers, supplying the hydrogen atoms needed to synthesize ammonia. The movement of the electrons creates current, and is the source of the small amount of electrical power generated by the reaction.

Scaling up

“One of the things my group does well is designing the interface between the enzyme and the electrode, so the enzymes can communicate with electrode surfaces,” Minteer said.

Several challenges remain to be overcome before Minteer and Milton’s smallscale process can find application at an industrial scale. One is the oxygen sensitivity of nitrogenase, another is the requirement of chemically-expensive ATP, a source of energy in cells and in nitrogen fixation. Milton said that re-engineering the reaction to circumvent the need for ATP would take the fuel cell “to the next level.” Until then, he said, the most notable and impactful aspect of this work is the production of ammonia without the massive energy drain characteristic of the industry standard process.

Minteer and Milton envisioned a fuel cell system that replicated the biological process of nitrogen fixation, using nitrogenase and hydrogenase, an enzyme graciously

“The real thing is not the quantity of ammonia produced, but that it’s possible to make electricity at the same time,” Milton said.

New Eco-Friendly

Concrete Developed

Rutgers’ Richard Riman invented energy-efficient technology that could help limit climate change

n the future, wide-ranging composite materials are expected to be stronger, lighter, cheaper and greener for our planet, thanks to an invention by Rutgers’ Richard Riman.

Inventors. The materials could be used for engine, interior and exterior applications. Other materials could perform advanced electronic, optical and magnetic functions that replace mechanical ones.

Nine years ago, Riman, a distinguished professor in the department of materials science and engineering in the school of engineering, invented an energy-efficient technology that harnesses largely lowtemperature, water-based reactions. As a result, he and his team can make things in water that previously were made at temperatures well above those required to thermally decompose plastics.

“It’s a foundational or platform technology for solidifying materials that contain ceramics, among other things. They can be pure ceramics, ceramics and metals, ceramics and polymers – a really wide range of composites.”

So far, the revolutionary technology has been used to make more than 30 different materials, including concrete that stores carbon dioxide, the prime greenhouse gas linked to climate change. Other materials include multiple families of composites that incorporate a wide range of metals, polymers and ceramics whose behavior can be processed to resemble wood, bone, seashells and even steel. A promising option is creating materials for lightweight automobiles, said Riman, who holds dozens of patents and was recently named a fellow of the National Academy of

Chemical Today Magazine | March 2017

Riman’s patented technology creates bonds between materials at low temperatures. It’s called reactive hydrothermal liquidphase densification (rHLPD), also known as low-temperature solidification. And it’s been used to make a wide range of ceramic composite materials at Rutgers, according to an article published last summer in the Journal of the American Ceramic Society. “Typically, we don’t go any higher than 240 degrees centigrade (464 degrees Fahrenheit) to make the composite materials,” Riman said. “A lot of these processes are done even at room temperature.” “I looked at how shellfish make ceramics at low-temperature, like carbonate crystals,

Richard E. Riman focuses on making ceramic materials under sustainable conditions.

and then looked at what people can do with water to make landing strips in Alaska and I said we should be able to do this with ceramics, but use a low-temperature chemical process that involves water,” he said. Riman came up with the idea decades ago but didn’t launch the technology until climate change became a bigger issue. “When it became important to investors to see green technology developed to address carbon emissions in the world, I decided it was time to take this technology commercial,” he said. “The first thing we did was show that we could make a material that costs the same as conventional Portland cement,” he said. “We developed processing technology that allows you to drop the technology right into the conventional world of concrete and cement without having to make major capital expenditures typically encountered when a technology is disruptive to the marketplace. We plan to do the same thing in the advanced materials business.” “When you can develop technologies that are safe and easy to use, it’s a game changer – and that’s just one of the many areas that we’re interested in pursuing,” Riman said.

SECTOR VIEW SKIN COSMETICS

‘SUPER’ SKINCARE WITH

‘SUPER’ FOOD O

ur skin has been bearing the dangerously damaging effect under the shroud of pollution, stress and unhealthy eating. This has led to a major shift in the way cosmetics is being perceived wherein the focus is shifting from powdered and dolled up faces to nourishing and rejuvenating the skin from within with the power of superfoods.

BY DEBARATI DAS

oday, everyone wants to be super fit, super healthy and super attractive. And to achieve this tag, the word ‘superfood’ has taken the imagination of health conscious generation. So, while these superfoods like kale, spinach, parsley are being tossed up into super healthy salads, the extracts of these superfoods are also widely being used as ingredients for cosmetics and skin care products to get super healthy skin. This shift in the cosmetic products has brought in the awareness that a ‘healthy skin’ is the key to ‘beauty’ rather than masking the face with foundation and makeup. And hence, superfood is being treated not only as the elixir of health but also skin. These food trends are increasingly influencing beauty and skincare regime. Avocado oil for skin moisturising, quinoa grains for hair strengthening, papaya for skin lightning…. the list of superveggies, superfruits, supergrains, that are being used in cosmetic products are endless. The organic cosmetic market is forecasted to be valued at $66.1 billion by 2020, according to a Future Market Insights report.

Chemical Today Magazine | March 2017

Skincare regime derived from nature is not new and has traditionally been used in many cultures for thousands of years. What is called superfood today is a local food item used in every kitchen in many parts of the world. It is only now that the cosmetics industry is acknowledging the power engulfed in these food and have reinvented it under the superfood tag.

products. Its Tulasara™ range showcases the Ayurvedic richness and the use of Turmeric in Indian pre-wedding ritual for glowing skin. The brand also brought out the goodness of Nangai Oil from Nangai nuts which are sourced from Melip and Mbonvor villages in Malekula island to explore the magical ways to repair spit ends.

used for scalp treatment and protection against dull and dry hair.

In this search for new superfoods, the cosmetics industry has been exploring the traditional spices, plants and vegetables of the East, diving deep into the ocean bed for rare algae and finding out new potential of the already in use foods.

Origins, a cosmetics brand from the US and one of the original brands of The Estee Lauder Companies, is known for its sustainable practices and plant-heavy skincare ingredients such as spirulina, spinach and green tea. One of its skin treatment lotions utilises reishi (lingzhi) mushroom, which is rich in water-soluble polysaccharides and is known for its immune-system-boosting properties. Its rejuvenating treatment cream uses the properties of self-hydrating Rose of Jericho, lychee and watermelon to repair and naturally moisture dry and dehydrated skin. Its foaming-face wash uses the antioxidant properties of white tea along with coconut and Oat Amino Acid.

Avocado: This good fat does more good to your skin than you can imagine. The Mexican fruit, rich in fatty acids naturally moisturises and helps repair skin. It is also a rich source of protein, potassium, vitamins E, A, K, B6 and C, fiber, folate, iron, magnesium, phosphorus and copper and has numerous skin and hair benefits. It hydrates dty skin, treats damaged hair, slows aging process.

The extracts of superfoods are increasingly being used in various cosmetic products from moisturising creams, foundation, sunscreen, soaps, handwash and various other skin care items so that the benefits can directly seep into the skin and heal the skin from within in a safe and organic manner. Sabinsa cosmetics, which has been promoting the use of natural ingredients and superfoods in its cosmetics products for long, has been actively using various superfoods like Emblica officinalis commonly known as Amla, Punica granatum or Pomegranate, Rosemary, Artocarpus lakoocha- a tree found in Indian Subcontinent and Southeast Asia and commonly known as monkey fruit or Monkey Jack, and Curcuma longa or Turmeric. The extracts of these superfoods is being used in various skin care products for skin lightening, anti-aging, moisturising, sunscreen, etc. Extracts obtained from green tender coconut water, which is packed with a powerhouse of micronutrients, is being used in Sabinsa’s various hair care products to promote hair growth. Global brand, L’Oreal uses quinoa husk in its cosmetics. Quinoa husk, considered to be waste of agro-food industry, contains saponins and polyphenols which can be used as essential cosmetic ingredient. L’Oreal researchers have proven exfoliating properties of the quinoa husk extract and is used in various products. Skincare brand, Kiehl’s, has been on the forefront of this trend of using superfood content on cosmetics for many years by using avocado oil in eye treatment products, argan oil in hair care products and lentil extract in skin care creams. While most of its products use the goodness of calendula, aloe vera, grape fruit, coconut, etc, one of its latest products uses quinoa husk extract for surface cell turnover. Another skincare brand, Aveda, has been promoting traditional skincare customs and rituals around the globe in its skin care

Chemical Today Magazine | March 2017

Here are some of the superfoods whose potential will be unearthed, explored and used to the fullest by the cosmetics and the skin care industry this year: Turmeric: Also called ‘the golden spice of life’ due to its numerous medicinal properties, has traditionally been used in the East for centuries in culinary and beauty regimes. It is now being appreciated by the global cosmetic industry which is incorporating this bright yellow root in various skincare products to brighten dull skin and provide solution with its antiinflammatory properties. Moringa: Also called the drumstick tree, is native to the southern foothills of the Himalayas in northwestern India and is known for its various medicinal properties. Every part of the tree – leaves, pod, fruits, sap, seeds, oil, flowers, roots and bark has medicinal properties. It is currently being used in beauty products for its anti-ageing, antioxidant and hair care properties. It is being used in various beauty products like moisturising creams, hair cleaning and rejuvenation etc. Kale: This cabbage like vegetable is the latest vegetable to be included in the list of superfoods. After dishing up various healthy recipes, kale is now creeping into skincare regime in the form of face packs, moisturisers, serums, and oils for replenished skin. These leafy green veggies are also being used for its antioxidant properties as first aids for skin. With the recent fad for purple food, Purple Kale, which has highest concentrations of nutrients including vitamin A, vitamin K and manganese, is also being increasing

Spirulina: This blue-green algae is a freshwater plant and an elixir for skin which can help speed up cell renewal and fight against fine lines giving an additional blast of amino acids, vitamins and fatty acids to your skin.

Chia seeds: These tiny seeds are packed with omega-3 and omega-6 fatty acids which give deep nourishment to the skin, hair and nails. It reduces inflammation, dryness, and increase circulation. Blueberry: You might have had blueberry smoothies and yogurt. But it’s time that you applied it on your face for a younger looking skin and fight ache. It also helps prevent premature greying of hair and facilitates hair growth. Goji Berries: This super berry power packed with vitamin C is not just good for complexion but also brightens and hydrates the skin. Carrot: Carrot oil is rich in pro-vitamin A which helps to heal and repair the skin. It is an ideal after-sun soother and repairs the skin after sun exposure giving a glow to the skin. Acai Berry: Anti-pollution cosmetics are on a rise to combat the after effects of various pollutants attacking our skin every day. Acai berry is packed with antioxidants to fight free radicals and pollution damage, it also comes heavily laden with omega oils which nourish and replenish skin. Spinach Leaf: And Popeye the Sailor Man had his can of spinach for strength. But that’s not it. Spinach leaves are packed with vitamins A, C, E and K which replenish the skin, while folic acid helps to keep complexion clear. Our mothers and grandmothers told us to finish our plate of green leafy vegetables. It sure took us a lot of time to understand the reason. Now these leafy veggies are finding their way into our lives not just as smoothies and desserts but also as creams, serums, and oils to help rejuvenate our skin. Various cosmetics companies have been constantly using superfood formulas packed with the goodness of kale, spinach, alfalfa, chia seeds to make safe, healthy and organic formulations for good skin.

FEATURE SOAPS & DETERGENTS GLOBAL DETERGENT CHEMICALS MARKET: TRENDS AND OPPORTUNITIES

oth chemical and biotechnology companies are trying to outshine each other for greater market share by offering high-performance enzymes for liquid detergents. Going forward, the competition in the market is slated to increase further with more players entering the arena, according to a report by Transparency Market Research

Overview Presence of a copious number of global and regional vendors makes the global market for liquid detergent chemicals highly competitive. Both chemical companies and biotechnology companies are trying to outshine each other for greater market share by offering high-performance enzymes for liquid detergents. Going forward, the competition in the market is slated to increase further with more players entering the arena. Growth opportunities remains high for suppliers that provide differentiated value, which allows them to sustain competitive pricing. Detergents are used as laundry detergent, biological reagents, fuel additives, soapless soaps etc. Of these, detergents account for maximum market share on account of their large-scale use. Fuel injector and carburetor component of Otto engines, for instance, are benefited by detergents that thwart fouling in fuels. Again, isolation and purification of integral membrane proteins in biological cells is carried out with the aid of reagent grade detergents. Soapless soap is a non-soap cleanser sans soap with a little acidic pH. Detergent chemicals find application as industrial and institutional cleaners, metalworking fluids, household detergents, and personal care products, among others. Detergents are manufactured using three process namely, the blender process, agglomeration process and slurry method.

Trends and Opportunities The primary growth driver in the global market for detergent chemicals is the swift pace of industrialization worldwide. Further, progress on the technology front has also been driving the market. Most vendors in the market are laying a lot of

Chemical Today Magazine | March 2017

emphasis on research and development of polymer technology that can add more value to detergent formulators. Another noticeable trend in the market is the growing thrust on green cleaning products and methods that use environment friendly ingredients in place of volatile organic compounds that cause dermatological and respiratory disorders. Posing a roadblock to the growth in the global market for detergent chemicals is the unstable prices of raw materials on account of the volatile oil and natural gas prices. The main raw materials used in formulating detergents are sodium sulphate, sodium silicate, palm stearin, Linear Alkyl Benzene Sulfonic Acid (LABSA) and Palm Fatty Acid Distillate (PFAD), among others.

Regional Outlook Geographically, the key segments of the global market for machine control system are Asia Pacific, North America, Europe and the Rest of the World. Asia Pacific, bolstered substantially by China and India, is predicted to outshine all other regions in terms of consumption of detergent chemicals. The Middle East and Africa are other prominent markets. In the years ahead, the US is anticipated to trim its market share because of the buying behaviour of customers. Europe, on the contrary is expected to gain market share.

Companies in the sector Some of the companies that maintain competition in the global market for detergent chemicals are AkzoNobel, Huntsman Corporation, Solvay, BASF SE, Dow Chemicals, Tata Chemicals, Procter & Gamble, Dial Corp, Clariant AG, Unilever, Shell Chemicals, Airedale Chemicals, Colgate, International Detergent Chemicals Ltd and Condea

GLOBAL LIQUID LAUNDRY DETERGENT MARKET: TRENDS AND OPPORTUNITIES

Liquid laundry detergent is produced using several ingredients such as soap, zeolites (water softeners), complexation agents (builders), bleach, and other enzymes. Liquid laundry detergent is mainly used to clean laundry. It has applications in two end user segments such as commercial and residential. Commercial applications of liquid laundry detergent include textile industry, laundry services, and hospitality industry among others. Its residential application includes household cleaning.

Growth opportunity Liquid laundry detergent is easy to apply and produces less wastage when used, on account of which it is gaining acceptance and is substituting soaps and detergent powders in the market. Population growth and increasing disposable income are expected to remain the major drivers of global liquid laundry detergent market. Increasing disposable income of consumers in emerging markets is driving the demand for clothes, which in turn has spurred demand for liquid laundry detergent. Additionally, growing population and increasing tourism activities have been key factors for increase in demand for liquid laundry detergent in hospitality segment. Increasing usage of laundry services across developing countries is also expected to help the growth of liquid laundry detergent market. Liquid laundry detergents are considered to be environmentally hazardous. Degradability of liquid laundry detergent coupled with European Unionâ&#x20AC;&#x2122;s regulation to ban phosphates in domestic products is expected to be a major market restraint. However, research & development activities for the manufacture of biodegradable liquid laundry detergent are expected to provide huge growth opportunities for the market.

Regional Outlook

iquid laundry detergent is easy to apply and produces less wastage when used, on account of which it is gaining acceptance and is substituting soaps and detergent powders in the market. Increasing disposable income of consumers in emerging markets has spurred demand for liquid laundry detergent, according to a report by Grand View Research Inc.

Chemical Today Magazine | March 2017

North America emerged as the largest consumer of liquid laundry detergent globally. The market in this region is characterized by high level of consumerism in textile industry. Asia Pacific emerged as the largest producer of liquid laundry detergents and is expected to become the fastest growing regional market in future. Increasing awareness regarding liquid laundry detergent and growing industrial investments in emerging markets such as India and China are expected to boost the growth of liquid laundry detergent market in this region. Increasing demand for liquid laundry detergent in Latin America is expected to drive the demand for the market in RoW.

Key Players Some of the major participants in global liquid laundry detergent market include Colgate-Palmolive Company, Henkel KGaA, Procter & Gamble Co, Unilever and The Dial Corporation among others. Other participants in the market include The Clorox Company, Sun Products Corporation, Church & Dwight, Reckitt Benckiser Plc, and Wipro Enterprises Ltd.

FEATURE PHYTONUTRIENTS

GETTING A LITTLE

EXTRA FROM FOOD H

aving a healthy diet of fruits and vegetables does not ensure optimum health as the food we consume is laced with harmful chemicals. Phytonutrients is the next level of nutritional supplements which is set to complete the dietary charts.

Chemical Today Magazine | March 2017

BY DEBARATI DAS

his generation, by large, is growing more health conscious as the awareness of healthy eating and healthy living is picking up pace. Vegan diet, superfoods etc. top the food chart nowadays. But have you wondered if we are really getting the maximum amount of plant nutrients from the fruits and vegetables that we consume or are the nutrients getting washed off due to the toxicity of soil, pesticides and the constant attack of various chemicals on plants? To address this, phytonutrients have begun gaining impetus in the foods and dietary supplements industries. Phytonutrients, or ‘plant- nutrients’ are certain specific, organic components found in plants that boasts of immense health benefits. Vegetables, legumes, nuts, grains and fruits are some of the rich sources of phytonutrients. These nutrients found in plants are produced by the plant to protect it from damaging environmental conditions like ultraviolet rays, predator pests, toxins, and pollutants while providing colour, flavour, and smell. Different plants and vegetables contain different phytonutrients and regular consumption of a varied mix of vegetables and fruits can boost the effectiveness of phytonutrients and considerably prevent or delay various diseases like reduction in blood pressure, increase in vessel dilation, improved vision, decreased inflammation, decreased LDL (low density lipids) cholesterol, and prevention of cellular damage.

Market Expansion Although, phytochemicals are best taken in by eating the foods that contain them, there has been a huge rise in the phytonutrients in the form of dietary supplements in the market which can be consumed in the form of tablets or health drinks as per requirement. The global market for phytonutrients was valued at $3.05 billion in 2014 and is projected to reach $4.63 billion by 2020, at a CAGR of 7.2 percent from 2015 to 2020, according to MarketsandMarkets report. Phytonutrients in plants can be found in the form of carotenoids, flavonoids, lycopene, resveratrol, and phytosterols - each of them serves a different purpose. For instance, carotenoids protect the body against the risk of heart disease, stroke, blindness, and certain types of cancer. They may also help slow the aging process, reduce difficulties associated with diabetes, and improve lung utility. Currently, carotenoids, phytosterols, and phenolic compounds are the most widely found and used phytonutrients in various sectors such as food & beverages, feed, pharmaceuticals, and cosmetics. Global carotenoids application may alone generate revenue over $2 billion by 2024, according to Global Market Insights while global phytosterols market size may surpass

Chemical Today Magazine | March 2017

$730 million by 2024. Flavonoids are the second most widely used phytonutrients.

trending drivers which may fuel industry growth.

These supplements are readily available and contain multiple phytonutrients. The demand has found further impetus due to growing health awareness among consumers coupled with rising health concerns, changing food habits and hectic lifestyle. Consumers also realise that phytonutrients are superior-quality foodstuffs with balanced nutrients. These supplements can plug the missing holes in nutrition intake in a normal diet plan.

Phytonutrients in the form of beverage consumption, such as energy drinks and sports drinks, would drive nutraceutical supplements demand among health conscious population. Vitamin E market may surpass 165 kilo tonnes by 2024. The shift towards natural and organic beauty products has fuelled the phytonutrients market in cosmetics industry where products including skin care, sunscreen lotions, hair care and perfumes are increasingly using natural ingredients.

Cashing on nutrients These disease-preventing properties have led to the transformation of phytonutrients to numerous commercial products containing phytonutrients in different proportions. Natural solutions that advance human health are in high demand and with this, microbial solutions is expected to witness a huge growth. Chr. Hansen, a global supplier of probiotics to dietary supplements, infant formula and dairy, is further strengthening its microbial platform with Lactobacillus rhamnosus GG (protected under the trademark LGG®), which is used in food and dietary supplements. “The markets for well documented probiotic strains are experiencing very strong growth in dietary supplements and drive an entire category in fermented milk products, such as yoghurt, kefir, etc. We believe that there are vast opportunities for the LGG® brand considering Chr. Hansen’s wide geographic reach and deep technical knowledge,” said Lasse Nagell, senior vice president, human health, Chr. Hansen. Additionally, the food & beverages, pharmaceutical and nutraceutical industries are constantly trying to come up with new methods to incorporate these phytonutrients in new avatars to entice customer’s choice. They are also being used as additives of food products such as bakery products, milk, sausages, spicy sauces, yogurts, spreads and margarine. Chr. Hansen came up with lactose-free milk with reduced sugar for consumers who perceive it as a healthier alternative. Most lactose free milk products experience flavour issues while manufacturers struggle with high cost of fermented dairy free of lactose. Chr. Hansen’s NOLA® Fit, retained the premium taste of dairy products produced at affordable cost by working on high specific activity of the enzyme over a wide pH and temperature. Apart from this, the Global Market Insights report that the pharmaceutical application would surpass $1 trillion by 2024. APAC, led by India’s pharmaceutical growth, may witness over $60 billion by 2024. Increase in health diseases such as cardiovascular diseases, cancer and diabetes are key

The immense health benefits of phytonutrients are being vigorously marketed to further drive its market globally. Also, increasing availability and cheaper cost of raw materials, improved extraction techniques, and diversified application demands are driving the demand for phytonutrients across the world. This has led to significant strengthening efforts in R&D to identify efficient sources to extract phytonutrients and meet the rapidly growing demand for phytonutrients. However, what good is a good diet if there isn’t any room for cheat foods. And to match up with “health conscious food loving” consumers who love to binge on a slice of pizza or a scoop of cake, Pharmachem Laboratories came up with a carb controller ingredient called DietSpice, which is a line of functional seasonings that can be sprinkled on food to help weight watchers absorb fewer calories from the starches in their meals. This ingredient is a proprietary extract of Phaseolus vulgaris, or white kidney bean. “No one would argue that a high-protein, low-carb diet is the way to go if you want to lose weight. But it is hard to stick to because we all love our starchy foods,” said Mitch Skop, managing director, Pharmachem. “The ingredient started at the very end of ephedra and the very beginning of the low carb craze.” The demand for phytonutrients majorly comes from Europe and will continue to dominate the global market in the near future owing to the rising health concerns in the region. The US, Germany, France, Italy, and China are the top five markets for phytonutrients and account for nearly 50 percent of the global total phytonutrients consumption, according to Marketsand Markets report. However, since stressed lifestyle, unhealthy eating, aging population and rising health concerns are becoming a universal phenomenon, phytonutrient market has a great growth opportunities in emerging markets and untapped regions. The phytonutrients industry is here to stay and explore new avenues of adding value to food.

INNOVATION SURFACTANTS

INNOVATING TO LAUNCH

CUSTOMIZED SURFACTANTS BY SAMIR RAWAL

he Huntsman Performance Products division has surfactants as a significant part of its portfolio with backward integration in EO at USA and Australia manufacturing assets. This business focuses on diverse applications including but not limited to Agrochemicals, Home and Personal Care, Paints & Coatings, Oilfield Chemicals, Textiles, Metal Working etc. At Huntsman, we constantly innovate to launch customized surfactants for our valued customer. Some of the themes are APE free surfactants, polymeric dispersants, and surfactants for multiactive ingredients etc.

Ostwald Ripening Particle size growth typically occurs as a result of the spontaneous thermodynamic process known as Ostwald Ripening. In simple terms, the phenomena occurs as a means of reducing surface energy. Larger particles will grow at the expense of smaller ones to minimise the exposed surface area. In the case of agrochemical substrates, the phenomena can be accelerated by increased water solubility. This facilitates ‘easier’ detachment, diffusion and re-attachment of the energetically unfavorable surface molecules.

1. Novel Dispersant For Suspension Concentrates PATENT NUMBERS: US8420573 & US8247353

TERSPERSE® 2612 dispersant is a novel polymeric dispersant for use in agrochemical suspension concentrates. It integrates Huntsman technology to create a dispersing agent that can provide improved formulation stability.

Introduction Despite advances in formulation technology, there are several challenges still faced during the development and commercialization of Suspension Concentrates (SC). These include:

Dispersant Synergy TERSPERSE® 2612 dispersant achieves enhanced performance through improved synergy with agrochemical substrates. Its unique chemistry improves interfacial adsorption, increasing the energetic favorability of smaller particles and thus limiting Ostwald Ripening. This is well highlighted by the microscopic comparison of two imidacloprid 600g/L SC formulations that have been subject to accelerated storage at 54° C.

• susceptibility to temperature • unwanted rheological phenomena • particle size growth All of these challenges can ultimately result in de-stabilization of SC formulations.

Particle Size Growth Particle size growth is one of the more common challenges faced in SC development. It can typically be well controlled by the use of dispersing agents, particularly those which are polymeric. TERSPERSE® 2612 dispersant is beneficial in that it can offer improved suppression of particle size growth versus existing industry benchmark polymeric dispersants.

Chemical Today Magazine | March 2017

2. Dispersants for High-Electrolyte Solutions To overcome herbicide resistance (or tolerance) and meet the ever demanding needs of effective crop management, more advanced and often challenging multi-active ingredient formulations have

become increasingly popular. A particularly desirable example is the dispersion of a water insoluble active ingredient in a water soluble active ingredient; in other words, a finely divided solid suspended in a highelectrolyte solution (HES).

The attributes of TERSPERSE® 3030 dispersant include: • Effectively disperses solid active ingredient in a salt or high-electrolyte solution

Introduction

• Prevents agglomeration/flocculation of solid dispersed phase

A novel polyamide condensate that has demonstrated the ability to solve difficult high-electrolyte formulation problems.

• Low use-rate required for effective dispersion, and typical SC preparative procedures can be employed

Problem Traditional dispersants are typically antagonized by high electrolyte environments.

Challenge To create stable, robust formulations where solid active ingredients are effectively dispersed in a high-electrolyte solution.

Example High-Electrolyte Systems

Particle Size Behavior The narrow particle size distribution offered by the use of TERSPERSE® 3030 dispersant both initially and following

Rheological Characteristics Increasing the volume fraction of terbuthylazine (Φ) in a HES formulation using TERSPERSE® 3030 dispersant resulted in excellent viscoelastic behavior

Chemical Today Magazine | March 2017

accelerated storage at 54°C shows its effectiveness in HES formulations. The use of a conventional polymeric dispersant will typically result in strong flocculation.

Comparison with Traditional Polymeric Dispersant

(Delta >> 45°) and a low shear modulus over a wide temperature range. This behavior is indicative of a dispersant which is working effectively even at such high active ingredien. concentrations.

INNOVATION SURFACTANTS Example High-Electrolyte Systems TERSPERSE® 3030 dispersant resulted in a phase stable solution with lower viscosity than the standard polymeric dispersant. As expected, TERSPERSE® 2500 dispersant, unlike TERSPERSE® 3030 dispersant, showed strong shear thinning and a significant yield stress which are indicative of flocculation.

Particle Size Behavior TERSPERSE® 3030 dispersant is unique when compared to conventional dispersants in that it’s been shown to display adjuvancy toward at least one active ingredient.

3. APE Free Surfactants APE’s (Alkyl Phenol Ethoxylates) are predominantly used in Textiles, and Industrial & Institutional cleaning industries. Choice of alternatives is very dependent on end applications and formulation criteria. Finding a one-for-one replacement is not straightforward and we would strongly recommend our customers to work with our specialized technologists to enable us to find what might be the best fit for their needs. Especially as application conditions can vary vastly - eg. pH, electrolyte levels, and temperatures. Alcohol ethoxylates can be used as alternatives to APE’s. This class of surfactant is core to Huntsman’s portfolio and we offer many varieties based on different hydrophobes with varying alkoxylation levels as befits the application. Our series of HYDRAPOLTM RP nonionic surfactants are high performance wetting and dispersing agents intended for general application as primary wetters, detergents, and scouring agents. They have a good biodegradability profile and are not identified as endocrine disruptors. As such they may be used as functional alternatives

to APE’s in most wetting and detergency applications. Methyl ester ethoxylates (MEE’s) are a relatively new class of nonionic surfactants based on vegetable oils. Huntsman’s series of SURFONIC® and TERIC® ME MEE’s are readily biodegradable with low aquatic toxicity profiles, and could be considered in some applications as APE alternatives. They have excellent emulsification properties and no appreciable gel phase in water compared to their AEO counterparts. They are most applicable under neutral pH conditions. With R&D facilities in USA, Europe, China, Australia and India, we are continuously focusing on innovation in surfactants for our key markets. Huntsman Corporation operates more than 100 manufacturing and R&D facilities in approximately 30 countries, within five distinct business divisions - namely Polyurethanes, Performance Products, Advanced Materials, Textile Effects and Pigments & Additives. HYDRAPOLTM, SURFONIC®, TERIC® and TERSPERSE® are trademarks of Huntsman Corporation or an affiliate thereof. Author: Samir Rawal is Country Manager, India Subcontinent, Huntsman Performance Products

Chemical Today Magazine | March 2017

INNOVATION SKIN REJUVENATION

EPIGENETIC APPROACH

FOR SKIN REJUVENATION BY JULIA COMAS, CRISTINA DAVI, ELENA CANADAS, SANDRA MENDEZ, RAQUEL DELGADO

Abstract

he epidermis is one of the most active tissues in terms of regeneration. This renewal capacity experiences a decrease with time, leading to the appearance of aging signs, such as wrinkles and dullness. The new peptide presented below showed a potential capacity to improve the epidermal regeneration process, with a suggested reprogramming effect of epidermal cells through the modulation of epigenetic mechanisms. When applied on the skin of volunteers, it helped accelerate the renewal time and improved their skin appearance.

Incorporating epigenetics into cosmetics Epigenetics is a concept based on the interpretation of gene expression and it represents a current trend in the cosmetics field with a strong interest placed on it. As a more clarifying way to understand such concept, genetics and epigenetics could be compared to the processes of writing and reading a book. Genes are known to be identical among the human beings, and these could be related to the written information of a book, which is the same for all of its copies. On the other hand, once this text is read by different readers, the emotions or reactions that it may cause can vary depending on their mood or previous experiences. The same thing could be extrapolated to epigenetics, being this related to the possible interpretations of the information stored in the DNA or genes which, depending on environmental and lifestyle factors, can result in different read-outs. Epigenetic processes represent molecular mechanisms able to regulate gene expression, activating or silencing it, independently of the genetic sequence of the genes. These mechanisms can vary from DNA methylation, modifications of histones, chromatin conformation and non-coding RNAs, such as the microRNAs (miRNAs). These epigenetic modifications determine how cells behave, playing an important role in certain physiological functions, such as the control of the fate of progenitor cells located in the basal layer of the epidermis (1).

The role of basal cells in epidermal regeneration In the basal layer of the epidermis reside the stem and progenitor cells, which have a significant regenerative capacity. Stem cells are unspecialized cells capable of undergoing divisions for long periods of time. They divide to generate progenitor cells, known to have a limited proliferative

Chemical Today Magazine | March 2017

potential and to eventually undergo differentiation into keratinocytes (2). The self-renewal abilities of basal cells are maintained by the transcription factors OCT4, SOX2, and KLF4, which are stem cell markers whose activity is repressed by microRNA-145 (miR-145) (3). Levels of this non-coding RNA are low in basal cells but increase during differentiation, with a concomitant decrease of the stem cell transcription factors. This switch is associated with changes in the characteristic markers present in the cells: basal cells express keratin 14 (K14) and p63 (required for their high regenerative potential), whereas suprabasal keratinocytes produce keratin 10 (K10). With age, progenitor cells decrease their division rate, reducing the generation of functional keratinocytes. This consequently decreases the efficiency of epidermal renewal and results in a more aged complexion (4). The latest launch of REPROAGE™ peptide, inspired by epigenetics, showed to modulate microRNA-145, aiming to support cellular reprogramming to

reactivate the progenitors pool and help epidermal self-renewal last longer. When tested on volunteers it helped accelerate epidermal regeneration, associated with an improved skin complexion.

Modulation of miR-145 and induction of stem cell factors Human keratinocytes from adult (HEKa) were used to evaluate the ability of the peptide to modulate the epigenetic factor miR-145 and to boost the stem cell transcription factors. HEKa were incubated with 0.01 mg/mL REPROAGE™ peptide for 24 hours, while non-treated cells were used as a control. miR-145 levels were then detected and quantified by means of a hybridizationbased assay. Another test was performed by incubating HEKa with 1 or 5 µg/mL REPROAGE™ peptide or by leaving the cells untreated as a control. Following incubation, the quantification of the stem cell markers SOX2, OCT4 and KLF4 was assessed by RT-PCR. After the treatment, results showed a 25.4 percent decrease (p<0.001) in the quantity of microRNA-145 and an induction of

the three transcription factors (Fig. 1), suggesting a cellular reprogramming effect and an improved self-renewal capacity.

Favoring progenitor cells of the epidermis Reconstructed human epidermis (RHE) were used to verify changes in specific cell markers after the treatment with 0.01 mg/ mL REPROAGE™ peptide or with the medium alone (control). Keratins K14 and K10 and the transcription factor p63 were separately detected in different epidermal models by means of immunohistochemistry. Levels of each protein were quantified through fluorescence microscopy images. After the active treatment, K10 decreased by 71.3 percent and K14 increased by 325.8 percent in a statistically significant manner (p<0.001), suggesting a stimulation of the basal layer, formed by the progenitor and stem cells (Fig. 2). The second treatment with the peptide resulted in an enhancement of p63 by 110.9 percent (p<0.0001), associated with an activation of the pool of epidermal progenitors for a better regenerative potential (Fig. 3).

Fig. 1. Gene expression of three different transcription factors (*p<0.05; **p<0.01).

Control

REPROAGE™ peptide

K 10 Fig. 2. RHE showing K10 and K14 in green (nuclei are colored in blue).

K 14

Chemical Today Magazine | March 2017

INNOVATION SKIN REJUVENATION Renewal and smoothing of the skin surface The epidermal renewal capacity and the changes in skin roughness were evaluated on two groups of female volunteers of different ages: 20 subjects aged 35-40 years old and 20 aged 50-55 years old. The subjects applied, twice a day, a cream containing 2 percent REPROAGE™ peptide solution and a placebo cream. Renewal of the stratum corneum was assessed on the forearm skin of the subjects by means of dihydroxyacetone staining. The stratum corneum turnover time (SCTT) was evaluated under different conditions for the two groups of volunteers, but also for a third younger group (1825 years old), which was used to obtain a correlation between SCTT and age from the 3 groups and hence, interpolate the years of rejuvenation after each treatment. A significant decrease in the SCTT was obtained in the skin where the cream containing REPROAGE™ peptide solution was applied on, reducing differences between age groups (figure 4). These results show an accelerated cell renewal and point to a revitalization of the skin. With respect to placebo, the SCTT in 3540 years old subjects treated with the active cream corresponded to that of 13 years younger skin. In 50-55 years old volunteers, the skin renovation was equivalent to that of 17 years younger. Skin roughness was measured on the area underneath the eyes by means of a microtopography imaging system (Fig. 5) and the average surface roughness (Sa) was obtained. Following the treatment with the active cream, skin roughness decreased in a statistically significant way after 28 days, being the results even better after 56 days: in the 35-40 years old group Sa decreased by 10.2 percent on average (**p<0.01) and up to 44.4 percent; in 50-55 years old volunteers, Sa improved by 13.7 percent (***p<0.001) and up to 41.6 percent, suggesting a smoothing effect by the active ingredient.

Radiant and better-looking skin To determine the improvement of the skin complexion, a clinical test was performed on 20 female volunteers (35-55 years old), who applied a cream containing 2 percent REPROAGE™ peptide solution to the face, twice a day. After 56 days of treatment, skin luminance was measured from high resolution

Chemical Today Magazine | March 2017

Fig. 3. Epidermal models with p63 represented in green (cell nuclei marked in blue).

Control

REPROAGE™ peptide

Fig. 4. Epidermal self-renewal time (vs non-treated skin: **p<0.01; **p<0.001; vs placebo: *p<0.05).

Fig. 5. Reconstructed 3D images of skin roughness. The reduction in surface depth can be seen as a tendency to change from blue to red colour. 28 days

35-40 years old

50-55 years old

0 days

56 days

Fig. 6. Photographs of one volunteer before and after the treatment.

photographs, resulting in an increase of 1.5 percent (*p<0.05). The enhancement in radiance, together with a general improvement in the skin appearance were further supported by the digital images of the volunteers (Fig. 6).

Conclusion By means of epigenetics through the modulation of miR-145 levels, which is involved in the regulation of epidermal differentiation, REPROAGE™ peptide

suggests a reactivation of the pool of epidermal progenitors for a longer-lasting epidermal self-renewal ability. When evaluated on the skin of volunteers, it showed to accelerate the stratum corneum renewal process, and it helped obtain a smoother and more radiant skin appearance. Hence, the peptide is intended to be introduced into cosmetic formulations aiming to counteract the slowdown of the skin regeneration process and to revitalize the dull complexion experienced with age.

BIBLIOGRAPHY 1. Weinhold B. Epigenetics: the science of change. Environmental Health Perspectives. 114(3):A160–A167, 2006. 2. Lavker RM, Sun TT. Epidermal stem cells: properties, markers, and location. PNAS. 97(25):13473-5, 2000. 3. Xu N, Papagiannakopoulos T, Pan G, Thomson JA et al. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell. 137(4):647-58, 2009. 4. Zobiri O, Deshayes N, Rathman-Josserand M. Evolution of the clonogenic potential of human epidermal stem/progenitor cells with age. Stem Cells Cloning. 5: 1-4, 2012. REPROAGE™ is owned by The Lubrizol Corporation or its affiliates. Authors: Julia Comas, Cristina Davi, Elena Canadas, Sandra Mendez and Raquel Delgado are from Lipotec SAU (Lubrizol Corporation company) in Gava, Spain

Chemical Today Magazine | March 2017

CASE STUDY CUTTING FLUIDS

HENKEL SUPPLIES

high-impact cutting fluid to closure system specialist Corvaglia Bactericide-free and economical in use

n the production of its platens for injection moulds, Swiss closure system specialist Corvaglia makes use of an innovative high-impact cutting fluid from Henkel that reduces the necessary bath make-up and top-up concentrations while offering considerably longer bath lifetimes. At the same time, the optimized, formaldehyde-free formulation results in a low-foam and low-odour emulsion. Together with licensees, partner companies and vertically integrated1 beverage bottlers, some 80 billion Corvaglia closures are injection-moulded each year. In this gigantic market, Corvaglia Mould AG, based since 2007 in Eschlikon, Switzerland, produces roughly 3,000 cavities each year, distributed over platens for 4 to 96 molds. Over a period of 25 years, the company and its two closure-producing sister organizations have established themselves as the world’s leading specialists in beverage bottle closures. Many closure designs are developed for big-name customers or have asserted themselves as quasi-standard in the market. Since the company’s founding, the focus has been on weight- and assembly-saving one-component closures on which both the shell and inner seal are injection-moulded in HDPE in a single process step. In both business areas – closures and moulds – Corvaglia is constantly investing in new equipment and machines. For further development and validation of mould and cap technology, a comprehensively equipped design and test centre was opened at the Eschlikon location in 2010. “Corvaglia is alone in having a fully integrated process chain from the allencompassing, efficient closure concept

Chemical Today Magazine | March 2017

through to 24/7 cap production,” said Daniel Burgi, responsible for milling technologies at Corvaglia Mould. “We aspire to be the top address for progressive closure cap solutions and this is why we seek support from the best-qualified suppliers.”

Consistent focus on sustainability In toolmaking, this refers not least to the cutting fluids that Corvaglia obtains through Thommen-Furler AG for its machining operations. This company based in Ruti near Buren (Switzerland) is the market leader in chemical and lubricant distribution, recycling/disposal, and wastewater and environmental technology for the entire Swiss industrial market. Corvaglia has the ambition to grow on the strength of product quality rather than quantity. Thus Thommen-Furler recommended six years ago the use of formaldehyde-free cutting fluid Bonderite L-MR from Henkel for metalworking. This range of water-miscible, finely dispersed emulsions is distinguished by its odourless, efficient and environmentally compatible formulations that provide very long bath lifetimes for drilling, turning, milling, sawing, tapping and grinding of metals of all kinds. This is coupled with an outstanding anti-corrosive and lubricant effect that is also capable of minimizing tool wear and the reject rate. “We used to be repeatedly confronted with a number of problems with cutting fluids, such as odor and deposits, excessive foaming, high drag-out together with the removed chips, and correspondingly high top-up concentrations,” said Burgi. “Since 2010, almost all of our machining has been carried out with Bonderite L-MR. The processes have thus become much cleaner,

and we have managed to reduce cutting fluid usage significantly overall.” The Henkel product has also shown itself to be much more tolerant to waters of different hardness – a beneficial feature, as Corvaglia obtains its process water from different sources. Andre Lagnaz, lubes sales engineer at Thommen-Furler, who visits his customers every three months to check fluid quality on site sums up the requirements of a modern, economical and sustainable cutting fluid: “The emulsion not only has to cool and lubricate reliably, but also has to run off quickly and be residue-free. High sludge accumulation in the coolant bath, high drag-out, and the oil film that used to be omnipresent in many machining shops do not occur with Bonderite solutions from Henkel anymore.”

Since its commissioning a year and a half ago, the 6,000-liter cutting fluid unit makes do with a weekly top-up of just 1-2% – the image shows quality control with a refractometer to measure relative density in °Bx.

When a new, fully automatic machining centre with a 6,000-liter cutting fluid system went into operation in Eschlikon in 2015, choosing the product was not difficult, as Henkel had upgraded its technology yet again with Bonderite L-MR 71-7.

Goal: 3-year bath lifetime The predecessor product was already well-accepted in metalworking worldwide – from pocketknife and clock production through to automotive and aircraft manufacturing. “For Bonderite L-MR 71-7, we have primarily further-optimized the formulation’s pH stability. Its patented emulsion system ensures particularly low foaming in waters with 5 to 100 degrees of German hardness. And the required bath make-up concentration is only 5 to 8 percent,” said Ulrike Mussigbrodt, business development manager distribution at Henkel.

Machining center Makino A92 with a 3-ton load capacity during the production of an injection mold platen at the Corvaglia Mould plant (Eschlikon, Switzerland) with the use of bactericide-free cutting fluid Bonderite L-MR 71-7 from Henkel

In terms of workplace health and safety, Henkel has also set new standards with its Bonderite L-MR 71-7. Its irritant potential on contact with the eyes has been minimized, which explains why the new product is not classified as hazardous under EU Regulation 1272/2008. “Our goal is market leadership for cutting fluids in Europe,” said Mussigbrodt. Andre Lagnaz sees good prospects for achieving this ambitious target. “On the new machine, we started with an initial concentration of 6.5 percent a year and a half ago and we are still on average well below 2 percent for the top-up concentration. Taking the differences in water hardness into account, this is extremely low. We have recorded similarly good values at other locations. Thanks to the longer bath lifetimes, our customers are benefiting from significant reductions in consumption and costs despite the higher purchase price.” In fact, Lagnaz has to remind his customers to avoid overconcentration during routine top-ups, as this can cause unnecessary costs. “Depending on chip volume, we add about 10 liters per week to the new machining center,” Burgi added. Drag-out is minimal. The bath life already matches that of other Bonderite products and promises to surpass it by a wide margin. Our goal now is three years.”

Each year, Corvaglia Mould produces 3,000 cavities for the production of closure caps all over the world.

Conclusion Metalworking enterprises looking for an effective as well as economic and environmentally compatible cutting fluid will find in Bonderite L-MR 71-7 from Henkel a product that combines outstanding performance with extra-long bath lifetimes. Low initial and top-up concentrations, minimized foaming and sludge formation, and low drag-out make for an extremely attractive cost-benefit ratio. The odourless, formaldehyde-free and environmentally compatible formulation keeps the workplace clean and healthy. Bonderite is a registered trademark of Henkel and/or its affiliates in Germany and elsewhere.

Ejection of screw caps for beverage bottles from a 96-mold tool with a 2.5 s cycle time at Corvaglia Closures Eschlikon

Includes all process steps from injection-moulding of the container preforms and closure caps, to stretch-blow or blow-moulding of the container through to beverage bottling.

Chemical Today Magazine | March 2017

MARKET UPDATES

HONEYWELL Inaugurates New Refrigerant Lab in India

oneywell inaugurated a state-ofthe-art refrigerant laboratory at the Honeywell India Technology Centre (HITC) in Gurgaon, Haryana, India. The laboratory was unveiled by Robert Kemp, deputy minister counselor, economic, environment, science and technology at the US Embassy, who dedicated HITC’s new lab in the region. The day also commemorates the fifth anniversary of the HITC, one of the company’s main technology development hubs outside of the US. The new laboratory will support local and regional OEM partners in designing, incubating and testing new refrigerants, while helping them transition to lowglobal-warming-potential (LGWP) alternatives. As one of the key signatories to the Kigali amendment to the Montreal Protocol, India has committed to cutting down hydrofluorocarbon (HFC) use. By reducing the use of chemicals with high global-warming-potential (GWP), the historic amendment aims to limit the

Chemical Today Magazine | March 2017

global temperature increase to no more than 0.5°C by the end of the century. “Honeywell is committed to providing next-generation solutions that are available today as an option to support the Indian government on transitioning from HFCs to environmentally preferable materials,” said Julien Soulet, managing director for Honeywell fluorine products in Europe, Middle East, Africa and India. “First mover customers in the region will benefit from the development of an industry based on environmentally preferable LGWP refrigerants that is aligned with the Government of India’s vision of Make in India,” said Rajiv Banavali, vice president and chief technology officer, Honeywell, advanced materials. Honeywell and its suppliers are in the middle of a $900 million investment programme in technology development and new capacity based on Honeywell’s hydrofluoro-olefin (HFO) technology, which helps customers lower their carbon footprint without sacrificing end-product performance.

ARLANXEO OPENS NEW KELTAN QUALITY LAB IN NETHERLANDS A

RLANXEO Holding BV said it is strengthening the competitive position of its global EPDM business in the ongoing challenging market environment, while at the same time optimizing its global footprint. For this it has opened a manufacturing quality control laboratory at the Chemelot site in Geleen, The Netherlands. The new 250 m2 facility is located beside the ARLANXEO Keltan EPDM plant. It is directly connected to the control room, which makes it possible to implement changes driven by test results immediately in the plant’s operations. Laboratory staff will carry out a full range of tests on the Keltan EPDM product,

Chemical Today Magazine | March 2017

including all industry standards such as Mooney and gel tests. Until now, these production quality tests have been carried out by external resources. The opening of the new Q-Laboratory comes as ARLANXEO marks the 50th anniversary of the introduction of Keltan EPDM. Keltan has a global footprint with plants in every strategic region with the ability to serve customers with premium products locally. Opening the new Q-Laboratory, Christian Widdershoven, head of Keltan® elastomers and managing director ARLANXEO Netherlands BV said: “This year, Keltan EPDM is marking its 50th anniversary. We are proud of the

product’s unrivalled track record and globally recognised high quality standards, established here in Geleen. “The opening of this new facility underlines the importance we place on ongoing quality and demonstrates our commitment to this product site.” “We are preparing for the future by developing a more sustainable EPDM production technology. Key examples include the use of Keltan ACE™ catalyst technology, and the recent introduction of Keltan® Eco EPDM grades, the world’s first EPDM rubber based on bio-ethylene,” he concluded.

INSIGHTS OUTLOOK 2017

OIL & GAS, ENERGY AND CHEMICALS IN 2017 For the year 2017, the oil & gas, energy and chemical industries must grapple with uncertainty that stems from various factors including the OPEC deal, Donald Trumpâ&#x20AC;&#x2122;s election, Brexit, slowing emerging economies, electric vehicles, and new regulations. The ADI team has assessed these factors and uncertainties in our outlook for 2017. 52

Chemical Today Magazine | March 2017

BY UDAY TURAGA Upstream - Oil • Oil prices have recovered following the OPEC deal – that Russia has joined too – to cut output although it’s too early to say if the deal’s contribution is purely sentiment or an actual price floor. Uncertainty around compliance with the deal will continue to foster anxiety especially since OPEC nations had elevated productions to begin with.

• Slowing supply and rising demand are more likely than seen in the recent past to strengthen natural gas prices although there is considerable uncertainty.

• Rising oil prices will encourage shale operators to bring uncompleted and, potentially, new wells online – with lower costs and higher productivity – and the North American resource is increasingly likely to serve as a price ceiling.

• LNG markets are struggling with oversupply leading to a renewed push among large buyers eg, Japan and South Korea, to weaken oil price indexation. Japan is liberalizing its LNG purchasing policies, Singapore is positioning itself as a regional hub, and India is actively trading LNG cargoes thereby increasing supply liquidity in the Asian market. In Europe, pipeline gas suppliers have reacted to protect market share in the wake of abundant LNG supply.

• Credit, which was financing capital spending for upstream independents and dividends for majors, is drying up. So, oil and gas players relied on divestments for cash flow and were supported by inflated acreage valuations particularly in the Permian and Appalachia M&A deals last year.

• Technology development and innovation around natural gas production and utilization continue to advance rapidly. In 2017, shale breakeven costs are likely to drop further, Petronas is closing in on shipping the first cargo ever from a floating LNG unit, and FSRU adoption is growing quickly.

• Oil demand growth is slowing in the medium term thanks to rising fuel economy of automobiles, growing penetration of electric and autonomous vehicles, declining role of energy-intensive manufacturing in emerging economies, and demographic shifts away from car ownership. In the near term, oil demand growth is fragmenting as large emerging economies are slowing while smaller emerging economies are surging.

Downstream, Refining and Fuels

• President-Elect Donald Trump’s promise to cut regulations has little policy detail but will support the positive industry sentiment.

Upstream - Natural Gas • The global natural gas resource base continues to be robust but supply is likely to moderate with North America likely to finally cut natural gas production in 2017. Even so, LNG production is likely to grow further with new trains coming online in 2017 at Gorgon, Ichthys, Wheatstone, and Sabine Pass. • Natural gas exports to Mexico, cold weather prospects, growing share of gasfired power generation, and rising LNG exports are all likely to strengthen natural gas demand although it is not growing fast enough relative to supply.

Chemical Today Magazine | March 2017

• Refining margins around the world declined dramatically in 2016. S. crack spreads fell due to lower product prices in export markets and higher crude oil prices relative to Brent while Asia and Europe were oversupplied from capacity and exports. • Companies that had built exposure to midstream and trading capabilities performed better than pure-play peers and will continue to be advantaged in 2017. • Consolidation among the pure-play refiners is likely to continue in 2017 and international participation in the US downstream segment will likely increase too. • Fuel regulations around sulphur limits, rising octane barrel values, crude oil and refined product exports, and pricing challenges with renewable identification numbers will occupy industry players in 2017.

Oilfield Services and Energy Equipment Markets • Upstream capex declined a little over 20 percent in 2016 better than the cuts exceeding 25 percent in 2015. Led by North American and national oil companies,

upstream capex will rise by about 5 percent in 2017. • In addition, oil and gas operators are clamping down on costs frustrated by the industry’s rising capital intensity. Since 2008, oil & gas capex growth has exceeded 6 percent but production has grown only 2 percent annually. • Capital spending will be allocated to smaller and near-term projects and it will likely be several years before operators will consider new deepwater, oil sands, largescale LNG, and refining projects • In such an environment of depressed capital spending, the share of aftermarket services in the oil and gas equipment market will continue to rise. • Mergers and acquisitions, which intensified in 2016 with Technip-FMC Technology and the GE-Baker Hughes deals being prominent examples, will likely continue in 2017 as players struggle with depressed capex and pricing flexibility. • Oilfield service companies and OEMs may see some revenue growth in 2017 mainly driven by new business activity and not from higher prices.

Chemicals • Economic strife in China, overcapacity, and weak private investment significantly hindered global chemical industry growth in 2016. • An emerging light vehicle market, positive trends in construction, and significant shale-linked capital investment is expected to spurn a recovery in 2017. • In 2017, chemical players will shift their focus to high-growth emerging markets and segments eg, automotive and housing, to reduce exposure to businesses that are struggling with depressed demand. • Further consolidation is expected to happen in 2017 as there is still a difficult economic climate and chemical manufacturers are seeking opportunities to increase operational scale and optimize cost.

Author Uday Turaga is CEO of ADI Analytics LLC.

INTERNATIONAL FOCUS NORTH AMERICA

CHEMICAL INDUSTRY WITNESSING

EXCEPTIONAL

RESURGENCE BY SHARVARI RALE

The 2008 economic crisis had dreadfully hit North America. However, the region, especially the US is currently on the way to recover, rapidly and cautiously. The $1 trillion chemicals market in North America was no exception to the economic downfall but is now witnessing impressive growth, as shale gas and speciality chemicals are predominantly attracting significant revenues to the chemicals market.

he US currently represents more than 75 percent of the total North American chemical industry. The next decade will see immense growth of the US as a key exporter within North America, and globally as well. While Canada is moving ahead gradually, Mexico is expecting healthy opportunities in near future. Now that boom in shale gas, specialities and oil slates are driving huge investments in an array of projects put forth by the petrochemical sector, several other industrial verticals are also raising substantial demand for basic as well as speciality chemicals.

Sub-segments continue to gather momentum in varied verticals Basic chemicals, including inorganic and organic chemicals, dyes, pigments, and plastic resins will continue to gather traction in multiple industrial verticals. Especially, plastic resins have been enjoying a little more momentous growth

Chemical Today Magazine | March 2017

due to robust demand from construction, automotive, and packaging markets. On the other side, speciality chemicals, such as plastic additives, coatings, sealants and adhesives, catalysts, and water treatment chemicals will experience performance-oriented sales over the next decade. Strategic government and private investments in the pharmaceuticals are likely to garner attractive opportunities for pharmaceutical chemicals, whereas consistent technological innovation and ever-evolving consumer behaviour will continue to fuel the consumer product chemicals segment. Automotive and aerospace industries will continue to generate demand for chemicals used in manufacturing of lightweight material panels. Similarly, segments, such as agaric chemicals, alternative plastics, polymers, and insulators will also see stable growth in near future. An important research finding concludes that sub-segments belonging

to bulk and fine chemicals, polymers, and formulation chemicals are observed to exhibit significantly larger market values, when compared to those in inorganic specialities and additives.

Shale resource development spurs abundant supply of natural gas Immense development of shale resources has been boosting the natural gas supply, increased the supply of natural gas and NGLs in North America. This will possibly promote competitive pricing of natural gas and NGLs in the long run. By 2020 end, NGL (especially Ethane) prices that have been historically low over the years, are anticipated to govern the North America’s chemicals market dynamics.

Volatility in prices of building blocks impacts market Scarcity of important building blocks of the chemical industry, including butenes, propylene, and butadiene will eventually result in volatile pricing, rather expensive. However, propylene prices could be stabilized in the long run, by increasing ondemand, application-specific production. Which chemical sectors will offer the maximum opportunities? • Bulk and vinyl resins are expected to benefit the most. • Among

commodity

polymers,

PVC

and polyethylene are likely to gain higher advantages. • Among the sub-segments that will possibly bag primarily supply-side benefits, bulk petrochemicals, such as butenes, butadiene, and propylene will top the list. Specific resins and synthetic rubbers are also likely to gain substantial supply-side benefits. • Organic intermediates, including methanol and ethylene derivatives, such as acetic acid, acetate chain, vinyl chloride monomer, and ethylene dichloride are expected to achieve major profits. • Among those that are projected to enjoy demand-side benefits, synthetic rubber will be the leading sub-segment. Engineering plastics will also be a crucial sub-segment. • Besides the aforementioned subsegments, electronic chemicals, acids, bases, and petrochemicals are foreseen to be the important chemical sub-segments.

Cognizance of supply-demand is the key to progress Over the next decade, leading chemical companies in North America are expected to encounter with several profitable opportunities. A majority of players will continue to strive for better product portfolio alignment, whereas others will attempt to restructure some of the key product segments in order to cater to the respective supply-demand scenarios and

demands from end-use industries. While major market players will be indulged in product portfolio realignment, many of the recognized equity firms are likely to remain behind-the-curtain market builders. Competition is already tough and may turn even more intense with continuously entering new players. In a bid to benefit from respective supply-demand scenarios, chemical companies are expected to keep a keen eye on both, supply costs and market dynamics. We expect the chemical industry in North America to welcome a fresh set of opportunities for manufacturers each year; the leading companies must be on toes in order to gain a competitive edge, capitalize on the suitable available opportunities, and appropriately position themselves in the North American as well as global chemicals market. How can chemical companies achieve the expected competitiveness in the chemical industry? With the help of top-notch product quality, strong product identification, perfect access to economically priced natural gas, highly efficient workforce, top-class research centres, and probably the most important, implementation of a robust regulatory guideline. The key to success lies in identifying the evolution in supplydemand and evaluating the potential impact of constant developments on upstream and downstream segments along the value chain. Author

Sharvari Rale is a content developer at Future Market Insights.

Chemical Today Magazine | March 2017

INTERNATIONAL FOCUS NORTH AMERICA

CLEANING

CHEMICALS INDUSTRY

Melissa Hockstad,

President & CEO, American Cleaning Institute (ACI).

Chemical Today Magazine | March 2017

Trends and focus on sustainability There continues to be great demand for cleaning, hygiene and disinfecting products in all sectors: consumer, commercial, and healthcare. Moreover, the cleaning product supply chain is innovating to meet their customer requests with innovative, sustainable chemistries and products. What you have seen over the past decade is companies embracing and embedding sustainable business practices throughout their operations. At the American Cleaning Institute, we will be releasing our fourth Sustainability Report later this year, where we hope to showcase the industry’s progress toward sustainable development. In 2017 we plan to put our recent industry materiality assessment – which is really a critical issues assessment – at the center of the report, and reflect on the topics that matter most to our industry and stakeholders. Within this new integrated report structure, we will highlight key metrics and showcase the work ACI has done to move the needle on our material issues. You can also expect a showcase of ACI companies and their individual sustainability progress. We’re fortunate to have so many leader companies in the cleaning product supply chain, in the US and around the world, that are addressing the core vision of the American Cleaning Institute: to enhance health and the quality of life through sustainable cleaning products and practices.

Innovative research forms core of the products and chemistries. Among the areas ACI has focused on: • ACI has laid out a detailed work plan for the US Food and Drug Administration (FDA) to provide extensive safety and efficacy data for the major ingredients used in consumer, commercial, and healthcare antiseptic products that align with requests made by FDA. We are working diligently to ensure that consumer and commercial customers and healthcare institutions continue to have access to these safe and beneficial products. • This past year, ACI published a study detailing research methods that used innovative non-animal techniques for filling hazard data gaps for 261 high production volume chemicals. The research methods eliminated the need for over 1200 animal tests that would have sacrificed 115,000 to 150,000 animals. The research also showed between $50 million and $70 million in associated testing costs were avoided. • Safety data on hundreds of chemicals in the US consumer cleaning product supply chain have been collected and are now available through the website of the American Cleaning Institute’s Cleaning Product Ingredient Safety Initiative. ACI recently announced that more than five years of work on the Initiative has been finalized, providing reams of publicly available data on ingredients in cleaning products. The data available on ACI’s Cleaning Product Ingredient Safety Initiative provides the scientific backbone to cleaning product ingredient safety. The website represents a significant transparency initiative for the cleaning products industry.

Challenges in cleaning chemicals industry The challenges that lie ahead for our supply chain continue to involve meeting a greater demand for sustainable products and chemistries by retailers, governments and NGOs, complex regulatory requirements in many parts of the world, difficult economic headwinds and currency fluctuations. Yet the cleaning product sector remains resilient. Consumers and commercial institutions use cleaning and hygiene products every single day, and our supply chain will continue to bring products to market that meet the demands of a growing world population.

Chemical Today Magazine | March 2017

REPORT BREWING ENZYMES

GLOBAL ANALYSIS AND FORECAST

2016 â&#x20AC;&#x201C; 2024 58

Chemical Today Magazine | March 2017

Overview With the increase of beer consumption across the world, positive lifestyle changes and growing disposable income in the developing countries, the demand of beer has gone up rapidly in recent years. In order to match the jump in demand the producers of beers has focused on brewing enzymes to increase capacity, reduce the time of production, aging of final products and allowed use of raw material alternative to malt ie. barley+enzymes. This change in process also results in production of same quality of beer in less time, and improves utilization of vessel, reduce energy consumption and low maturation duration with high beer quality. There are different type of enzymes which come in to use at different brewing process of producing beer and also used to modify the taste and content of beer, producing light beers, containing less calories. The market for brewing enzymes is growing but not every player in the beer industry uses brewing enzymes and really few accept the use of brewing enzymes in the production process.

Segmentation Brewing enzymes market is majorly segmented by the enzyme type, by process, by function and region wise. On the basis of enzyme type, brewing enzymes used during brewing process of beer segmented as amylases (carbohydrate enzymes), proteases (protein enzymes), peptidases, and Beta-glucanases and xylanases (cellulose enzymes). Other important

brewing enzymes are pullulanases amyloglucosidases and Alpha-acetolactatedecarboxylases. Each of these enzymes are important for brewing and every enzyme have different function resulting in fast brewing of beer. The Îą-amylases is one of the most versatile enzymes most widely used enzyme because it has abundance of starch, and find itâ&#x20AC;&#x2122;s applicability if applications from the conversion of starch to sugar syrups in brewing industry. Brewing enzymes can be also segmented on the basis of function like increasing free amino nitrogen production, improve filtration, and to reduce the presence of polysaccharides like glucans which are viscous in nature. It also increases fermentable glucose production during the light beer production. Basically, brewing enzymes results in enhanced chill proofing, cold haze and definitively faster maturation. Brewing enzymes market can also be segmented on the basis of geography but the segmentation is done one the basis of parent market trends ie. brewing market. China is one of the major player in AsiaPacific market and rules the market with respect to demand of brewing enzymes. North American region has high demand of brewing enzymes due to huge production of beer in US, followed closely by Europe, pertaining the demand of brewing enzymes, due to high production of beer in Germany, UK, Poland and Spain. The growth will be moderate to slow due to maturity in developed regions Western Europe and North America causing rapid growth in the Asia/Pacific and other developing regions.

Drivers Brewing enzymes market is driven by growth in beer and industrial enzyme market. Brewing industry have grown quickly in recent years and shows promising growth in coming years from the developing regions, impacting the growth of brewing enzymes markets positively. Also with increasing demand of light beer, due to rise in health consciousness and increasing buying power of the developing nation, the developing nations will steer the growth of brewing enzymes market. Multinational players continue to make huge investments to grow their market coverage and collaborating with domestic operators, to tap markets in different regions, will also result in demand of brewing enzymes. Hence, it is possible to alter the taste and colour of beer by adding enzymes during the brewing process, the producers are not shying away with experimenting and launching new flavours in the market.

Key Players Few of the major user of brewing enzymes are categorized under brewing enzymes buyers (demand side), and brewing enzymes suppliers. Major brewing enzymes users are Miller Coors (US), SABMiller (UK), Heineken NV, A B Miller Plc, Anheuser-Busch InBev, Carlsberg Group, Diageo Plc, Tsingtao Brewery, Boston Beer Company and Beijing Yanjing Brewery. Major suppliers of brewing enzymes are AB Enzymes, Advanced Enzymes, Danisco (DuPont), Novozymes, DSM and Amano Enzyme. Source: Transparency Market Research

REPORT CAR WASH DETERGENTS & SOAPS

ANALYSIS AND FORECAST ASSESSMENT

2016 – 2026 60

Chemical Today Magazine | March 2017

utomotive industry is one the prime contributors to the overall GDP, which is anticipated to increase significantly in the foreseeable future. Factors such as increased vehicle population, growing disposable income of consumers leading to consumer inclination towards improved car care services are driving the demand for auto detailing among consumers across the globe.

online retailing, and automotive parts and accessories outlets. Car wash detergents and soaps market is used for both residential and industrial purpose.

Auto detailing involves a process of making an automobile look better including waxing and cleaning from in and out to top and bottom of an automobile. Automotive detailing process includes car wash, paint, trim, wax, wheels and tyre cleaning, interior vacuum, polishing, cleaning for reconditioning and others. Among all aforementioned, car washing is gaining significant traction among consumers across the globe.

Geographically, the Car Wash Detergents and Soaps market is segmented into seven regions including Japan, Middle East and Africa, Eastern Europe, Asia Pacific excluding Japan, Western Europe, Latin America and North America. North America is anticipated to witness significant growth in the next five to six years. This is attributed to new product launches and technological advancements by car wash detergent and soap manufacturers, catering to the demand for consumers. Owing to increasing consumer inclination among consumers for car washing, Asia Pacific excluding Japan is expected to be potential market for car wash detergents and soaps market in the foreseen future.

Segmentation

Dynamics

Car wash detergents and soaps market is segmented on the basis of product range, volume capacity, price range, product type, distribution channel and end users - for both car wash detergents and car wash soaps.

Increasing per capita income has led to paradigm shift in consumer lifestyle, resulting in consumer inclination towards discretionary services. In addition increasing growth of automotive industry, awareness about improved car washing methods have led to surge in consumer database especially for commercial car washing services. This is in turn anticipated to drive the demand for car wash detergents and soaps among consumers. In addition, shift from manual washing to automatic washing has fueled the demand for car wash detergents and soaps among automotive service stations at a significant rate in recent years.

On the basis of product range, car wash detergents and soaps market segmentation includes complete care, wheel, wheel and tyre, and others. On the basis of car wash detergents, the Car Wash Detergents and Soaps market is segmented into 1 gal, 48 oz, 10 oz, 11 oz, 12 oz, 14 oz, 16 oz, 18 oz, 20 oz, 23 oz, 24 oz, 26 oz, 28 oz, 32 oz, 33.8 oz, 4 oz, 40 oz and 5 oz. Based on price of different car wash detergents, the market is segmented into below $ 5, between $ 5 to $ 10, between $ 10 and $ 15, between $ 15 and $ 20, between $ 20 and $ 75 and above $ 75. Similarly, on the basis of volume capacity, car wash soaps are segmented into 20 oz, 64 oz, 48 oz, 16 oz, 23 oz, 10 oz, 8 oz, 11 oz, 18 oz, 26 oz, 28 oz, 32 oz, 24 oz, 33.8 oz, 12 oz, 14 oz and 40 oz. Based on price of different car wash soaps, the market is segmented into below $ 10, between $ 10 to $ 20, between $ 20 and $ 50, between $ 50 and $ 100, between $ 100 and $ 150, between $ 100 and $ 150, between $ 150 and $ 200 and $ 250, between $ 250 and $ 500, between $ 500 and $ 750, between $ 750 and $ 1000, between $ 1000 and $ 1250, between $ 1500 and $ 2000, between $ 2000 and $ 2500 and above $ 3000. Based on the type of product, the car wash detergents and soaps market is segmented into liquid-based, gel-based and foambased. On the basis of distribution channel, car wash detergents and soaps market is segmented into department stores, supermarkets and hypermarkets,

However, water conservation is a concern, which restricts the adoption of commercial car washing among consumers and thus, might restrain the car wash detergents and soaps market growth. Although, water conservation is a concern, development of equipment such as pressure washer, wherein the pressure of water stream and amount of water used is preset is an added advantage for car washing among both industrial and domestic end-users.

Key players Some of the players in the Car Wash Detergents and Soaps market include Meguiarâ&#x20AC;&#x2122;s Inc, Griotâ&#x20AC;&#x2122;s Garage, Chemical Guys, 3M Co, Yac Chemicals Limited, Mothers and The Armor All/STP Products Company among others. Car wash detergents and soaps market is fragmented in nature with large number of players at regional level. There leading car wash detergent and soap players are engaged in developing biodegradable formulas ensuring compliance with eco-friendly environment. Source: Future Market Insights

REPORT COSMETIC INGREDIENTS

GLOBAL ANALYSIS AND OPPORTUNITY

2015 â&#x20AC;&#x201C; 2025 62

Chemical Today Magazine | March 2017

osmetic ingredient market has changed a lot over the course of time. Since time immemorial, human beings are using different types of cosmetics to enhance their physical appearance, which in turn makes people feel more confident and pleasing in nature. It is due to growing demand for beauty products that market is flooded with various cosmetic products. The multi–billion dollar industry is growing at a lightning speed to meet the consumer demand.

Segmentation

Cosmetic ingredients are the specific sets of substance that are used in the formulation and composition of cosmetics. Any kind of impurities in raw materials and subsidiary technical materials are not considered as ingredients, hence water is also considered as separate ingredient. At present, various cosmetic business entrepreneurs use more than 5000 available cosmetic ingredients to offer selected cosmetics products.

Alpha hydroxy acids, beta hydroxyl acids and talc are some of the examples of commonly used cosmetics ingredients. Among all these product type, surfactants are expected to hold the market dominance throughout the forecast period, however, conditioning polymers is projected to grow at the highest CAGR between 2015 and 2025.

Drivers & Restraints

•

Skin Care

•

Nail Care

•

Make up

The demand for good quality cosmetic products is fuelling the cosmetic ingredient market. Changing lifestyle specially in developing regions of Asia Pacific and Latin America brings a sea of opportunities to cosmetic ingredients manufacturers and suppliers. Increase in per capita income, rising awareness about beautification and increasingly urbanized population is offering momentum to the growth of overall cosmetic industry which in turn is escalating the cosmetic ingredients market to its zenith. Though cosmetic industry market size is growing at an impressive rate, various regulations prohibiting the use of certain chemicals as ingredients is a major challenge to the cosmetic ingredients manufacturers. In APAC, China and ASEAN regions are some of the most lucrative regions for increase in consumer spending and rise in GDP.

Chemical Today Magazine | March 2017

On basis of product type • Surfactants • Emulsifiers • Antimicrobials •

UV absorbers

• Emollients •

Conditioning Polymers

• Others

On basis of end-use applications

• Others Skin care and make up are the two most lucrative markets for chemical ingredients manufacturers. Together, they account more than one–fourth of total cosmetic ingredients market. Changing lifestyle and increasing awareness about skin care is boosting the demand for skin care applications.

Region-wise Outlook On the basis of region, cosmetic ingredients finds its market scope in North America, Latin America, Middle East & Africa, Europe and Asia-Pacific. North America and Europe dominates the cosmetic ingredients, however, Asia Pacific and Latin America are expected to be the most promising regions in terms of incremental

opportunities lying ahead for generating high revenue. Cosmetic ingredient market is highly regulated in Europe and North America. China, India and ASEAN are the key promising countries driving the cosmetic ingredients market in AsiaPacific. Rapid growth of urbanization coupled with growing desire for skin care is expected to offer above average growth to cosmetic ingredients market in AsiaPacific. Brazil leads the cosmetic market followed by Mexico in Latin America. As per the CANIPEC, the Mexican personal care industry’s national chamber and association, there are more than 64 business enterprises operating in personal care market that are worth approximately $ 14 billion in Mexico.

Key Players Company needs to meet the stringent quality norms before marketing their key ingredients. It is due to these factors that the market in North America and Europe is consolidated and is dominated by list of key cosmetic ingredient manufacturers and suppliers. Some of the market participants in the global cosmetic ingredients market are BASF SE, The Dow Chemical Co, Ashland Inc, Rhodia, DuPont Tata & Lyle Bio Products, Sederma Inc, Sumitomo Group etc. Companies are investing heavily and are entering into mergers and acquisitions to tap the cosmetic ingredient market potential globally. For instance, Sumitomo Group is expected to acquire active cosmetic ingredient business from Kyowa Hakko Europe GmbH in order to advance its cosmetic ingredient business in Europe. Going through these points, there is no doubt that cosmetic ingredients market hold good market prospects in near future, thereby is anticipated to grow at impressive CAGR during the forecast period, 2015-2025. Source: Future Market Insights

REPORT SOY-BASED SURFACTANTS

INDUSTRY OUTLOOK & FORECAST 2016 â&#x20AC;&#x201C; 2023

ncreasing use of renewable resources coupled with rise in environmental awareness is likely to drive soy-based surfactants market. Global biosurfactants market size is estimated to exceed 500 kilo tonnes by 2023 growing at a CAGR of over 4 percent and is likely to be worth more than $2.5 billion by 2023. Soybeans are an important source of three natural products namely soy lecithin, protein and saponin. Lecithin dominated the soy-based surfactants market demand over the past few years. Global soy oilseed production was estimated at more than 280 million tonnes in 2014. Stringent government regulations owing to environmental concerns are likely to hamper synthetic detergent demand. Renewable materials such as seed oils & animal fats coupled with technological advancements are likely to counter challenges for soy-based surfactants market growth. Seed oil substitution can significantly reduce carbon footprints into the atmosphere. Lecithin can be derived from animal source such as egg yolk, but is too expensive for industrial applications. It is predominantly obtained from plant seeds, particularly oilseeds as they are abundantly available at competitive pricing. Soy lecithin market finds preference in industrial applications to be used as a stabilizer, antioxidant, emulsifier, nutritional supplement and wetting agent owing to structural & compositional properties. Soy-based surfactants market price trend will be critical in determining industry acceptance.

Chemical Today Magazine | March 2017

Soy lecithin was granted GRAS status by the FDA and is also confirmed safe by WHO. This factor is likely to positively influence soy-based surfactant market growth. It is widely used for applications in food industry with content ranging from 0.1 to 0.2 percent, and added to food products to enhance shelf life and quality. For example, lecithin is added in chocolates to reduce viscosity whereas it enhances the freshness & volume in baked goods. It is also used in food supplement applications for improving memory and cardiovascular health. Soy proteins market offers three major forms which depend upon protein content namely flours, protein concentrates and protein isolates. Protein concentrates are the most refined with purity of approximately 90 percent. They are widely used as nutritional & functional ingredients in food applications. Their presence also enhances the color, texture and flavor of food products. For example, in baked products, they are used for emulsification of fats & other ingredients which improves the shelf life. Soy protein isolates market finds uses in emulsified products such as liquid whipped toppings and coffee whiteners. They are also used as binders and emulsifiers in processed meat applications. These aforementioned factors are likely to drive soy based surfactants market. Growth in soybean oil production coupled with decline in dietary applications owing to health concerns is likely to accelerate its use for non-food applications such as surfactants, lubricants, plasticizers,

bio fuels and printing inks. It is used as fermentation substrate or raw material for sorphorolipids, rhamnolipids and mannosylerythritol lipids. Soy-based surfactants market also has potential opportunities in medical applications for solid lipid nanoparticles with size ranging from 80-350 mm used for an anticancer drug delivery, Dox (doxorubicin hydrochloride). A number of products are available in the market for applications such as household detergents, agricultural chemicals, personal care, oilfield chemicals, textiles and food processing. United Soybean Board (USB) is expected to sponsor research in this area. Biobased products under the brand name Sophoron and Ecos are used for household detergents applications. Compare, Liberate, Agnique are used for agricultural applications. Chemonic is used for personal care applications. Arquad and Actrosol OY67 are used for oilfield chemicals & textile applications respectively. Actrosol OY-75 and Yelkin, Ultrayech & Beakin lecithin are used for paints & coatings and food processing applications. The global soy-based surfactants market share is consolidated and is characterized by the technological advancements to develop cost effective product. Key companies operating in this market include Saraya Co Ltd, Loveland Products, Noveon and Illionois. Other prominent manufacturers include Sinerga Cosmetic Company, Cognic GmbH, AkzoNobel, Koch Industries, Georgia Pacific Corp and ADM. Source: Global Market Insights Inc

ACADEMIC R&D

ENZBOND TO MAKE FAST,

EFFECTIVE ENZYME DEVELOPMENT A REALITY EnzBond, a new biotechnology company from Oxford University, has been formed to commercialise in-silico technology, which makes utilising enzymes in drug manufacturing both cost-effective and time-efficient. 66

Chemical Today Magazine | March 2017

t present, discovering the right enzymes for production in drug development can prove both prohibitively expensive and time consuming, as identifying the right enzyme is a trial and error process that can see companies go through potentially thousands of enzymes during the search. This prevents the penetration of enzymes in the industries like pharma where effective and green technologies are crucial. EnzBond’s in-silico technology allows the company to examine the potential properties of these enzymes virtually, rapidly speeding up the process. Compared to rival biocatalyst discovery firms, EnzBond’s technology has demonstrated itself to be at least ten times faster and far more accurate. The company is currently in discussions with utilising its product with major pharmaceutical, agricultural, cosmetic, and synthetic biology firms. “The potential to apply enzymes to current production methods not only opens up the potential of cleaner processes but also potentially significant reductions in cost for critical compounds such as antivirals and antibiotics. We are excited to see what sectors our technology can terraform,” said Robert Simion, chief technology officer at EnzBond. EnzBond is also the first Oxford spinout developed by students since NaturalMotion, which was sold to games company Zynga for $527 million in one of the largest spinout exits on record. Typically, spinout companies are either led or advised by an academic founder. In the case of EnzBond, the founders did everything from develop the underlying technology to pitching the technology to pharmaceutical partners and investors while PhD students, and officially founded the company upon completion of their studies. “The process has been both rewarding and challenging. At EnzBond we had to build our strength as we go, learning all the aspects of business development in real life. Looking back, I can say that this experience is priceless. There is no bigger reward than achieving goals that seemed to be impossible before. But that was just the first step; we now have a great team with invaluable experience and many more ‘impossible’ targets to reach,” said Alina Rakhimova, chief executive officer at EnzBond. Oxford University Innovation, the research commercialisation company of Oxford University, was involved with spinning out the company, while Oxford Sciences Innovation, the spinout investment company for Oxford University, has backed EnzBond with £350,000 in seed financing. “We view this as an industry ripe for disruption and are excited to back founders with the right mix of skills to have an impact. In-silico methods have yet to properly penetrate enzyme design and we are confident that EnzBond’s technology has the answers,” said Lachlan Mackinnon, principal at Oxford Sciences Innovation.

Chemical Today Magazine | March 2017

ACADEMIC R&D

OXYTOCIN IMPROVES SYNCHRONISATION IN LEADER-FOLLOWER INTERACTION A new study from Center for Music in the Brain (MIB) shows that participants receiving oxytocin – a hormone known to promote social bonding – are more synchronized when finger-tapping together, than participants receiving placebo.

52 68

Chemical Today Magazine | March 2017

hen standing in a crowd at a concert, clapping hands along with the music on stage, it may be that people with higher levels of oxytocin are better synchronised with the beat of the music than those with lower levels of oxytocin. A new study from Center for Music in the Brain (MIB) Aarhus University/ The Royal Academy of Music, Denmark, published in Scientific Reports recently, shows that participants receiving oxytocin – a hormone known to promote social bonding – are more synchronized when finger-tapping together, than participants receiving placebo. This effect was observed when pairs of participants, placed in separate rooms tapped together in a leader/ follower relationship. When people synchronise their movements together, for example by walking in time,

Chemical Today Magazine | March 2017

clapping or making music, they seem to like each other more and report feeling greater affiliation with each other. Oxytocin is a naturally occurring hormone that has been shown to promote social interaction, such as cooperation and affiliation. However, until now it has been unclear whether the social effect of oxytocin is a direct one, or whether oxytocin in fact primarily affects synchronisation and only secondarily social behaviours.

Highlights how music creates and maintain social cohesion We set out to test these questions by measuring whether increased levels of oxytocin affected how pairs of participants synchronised together to a steady beat. One group of pairs received oxytocin through nasal spray, and another group received a placebo, also through nasal spray. Our

results indicate that oxytocin indeed affects synchronisation between participants but we did not find that oxytocin influenced how much tappers liked their tapping partners. The followers in the oxytocin group were less variable in their tapping to the beat suggesting that they were better at predicting the taps of their leaders. Thus oxytocin’s social effect may be explained by its role in facilitating prediction in interaction, even in the absence of subjectively experienced social affiliation. The ability to synchronise to a musical beat is largely a human skill. Our study contributes to our understanding of how this form of human behaviour is affected by socio-biological factors, such as oxytocin and leader-follower relationships. It also highlights how music creates and maintains social cohesion in an evolutionary perspective.

ACADEMIC SPEAK FOOD PROCESSING

IN SEARCH OF ‘GOOD’ FOOD Anurag Singh talks at length about how maintaining the quality of food is one of the major concerns today and the ways in which improved food processing/ technology can enhance food quality. Singh is Assistant Professor in Department of Food Science and Technology at National Institute of Food Technology Entrepreneurship and Management (NIFTEM), Haryana, India.

Brief about your current research. Currently I am working in the area of shelf life extension and value addition of fresh fruits and vegetables so that the wastage of fresh produce may be minimized. The farmers are not getting the right value of their produce. If a nominal change in the form of these produce is done, the income of the farmers can be increased. Moreover, these agro produce are rich source of numerous bioactive components of our use but due to poor infrastructure and lack

Chemical Today Magazine | March 2017

of knowledge, we are losing these valuable products. So we are trying to develop various protocols for shelf life extension and value addition for various crops.

Research in the field of food processing/food technology. Its true that now we have understood the importance of a healthy and safe food. That’s why many researches are being done in the area of food processing/ technology. There was

a time when we were concerned only about the quantity of food but now awareness has increased. The consumer is now concerned about the composition of food products, its shelf life, health effects etc. This awareness and new studies revealing the ill effects of various food components are the driving force for the researches in the area of food processing so that a healthy and safe food product may be delivered to the consumer. This will surely grow in future.

Role of green chemistry in food processing/technology. Green chemistry has direct relation with the food processing sector. The biggest challenge for the food processing sector is to ensure the safety of the product. The major threat to the food safety is from the raw materials used. The pesticide residues and heavy metals are the main problems. If the use of chemical fertilizers and pesticides for the crops is stopped, and if the chemical waste is not disposed in water, surely the problem of food processing sector would be minimized. Biopesticides if used by the farmers, the processor can offer a safe product to the end consumer.

Improving safety in food items to meet consumers’ demands. As I have already mentioned that today’s consumer is very much aware about his food. It’s a very common practice to look on the information panel of any packed food item to know what are the ingredients, what is the expiry date, is there any kind of allergic material used etc. Surely there is a demand of safe and hygienic food product. In my view, if Good Agricultural Practices (GAP), Good Manufacturing Practices (GMPs) and Good Hygienic Practices (GHPs) are followed by the farmers and food processors, we might be able to offer hygienic and safe food to the consumer. We need to mainly work upon on the raw material. If a good quality raw material is available, a safe finished product can surely be delivered. Additives that have any ill effect on human health should be strictly banned. Strict legislations are required to avoid the use of these additives. Also, controlling the unorganized food sector is the main challenge.

Technologies used to test food safety. Food safety is comprised of various factors. A food, depending upon the raw materials used and the processing method adopted, has to be tested for various things. Commonly we take microbial contamination as the major threat to the food safety but types of adulterants, use of

Chemical Today Magazine | March 2017

food additives beyond limits, any kind of foreign matter, any kind of toxins, any kind of allergen, chemical residues etc. are also equally important. Various microbiological testing methods are used to check the presence of pathogens. Chemical analysis methods are used for checking the adulterants. Physical methods like Fourier Transform-Infrared Spectroscopy (FT-IR), Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-MS (LC-MS), Scanning Electron Microscopy (SEM) and X-Ray Microanalysis etc. are being use to detect the foreign material in any food product. Various immunological assays are used to detect the toxins available. Allergens are detected using various Immunochemical methods (ELISA) (dipsticks), DNA-based methods (PCR) and Mass spectrometry. Now-a-days, ready-made kits are also available to detect the toxins and allergens.

Current concerns and importance of food additives/ preservatives. Food additives/ preservatives are added to improve the food quality and to extend the shelf life but in recent years there are so many studies that came up with the adverse effects of some of the additives/ preservatives. Recently we have heard about bromate that is being used in bakery products. So, as the science/ technology is advancing, we are gaining more information for the additives being used in food processing sector. Though there are limits prescribed in regulations but the implementation at ground level particularly in unorganized sector is difficult. There is an urgent requirement to find the suitable alternatives of such kind of additives so that the safe food product may be made available without compromising the quality of the product.

Functional foods to improve health of people. Since, consumers are now more conscious about their health, increased demand of functional foods can be seen in the market. In recent years we have seen some good functional foods entering food market starting from probiotic drinks to high dietary fibre cookies. Products claiming reduction in cholesterol, improving gut flora or preventing other problems can be seen easily. These products are definitely more beneficial to health than their counterparts. Junk foods have become an integral part of our life, particularly youth and kids, that is causing various health problems. So use of these functional foods

are surely a good option to improve health.

Challenges in the food processing/food technology segment. If we talk about the food processing sector in India, there are many challenges. Seasonality of crops, huge wastage of produce at farm level, poor storage infrastructure, poor transport facility particularly reefer vans, non-availability of trained man-power, taxation and various regulations at state and central level are the main challenges faced by the industry. That’s why still the food processing sector is majorly unorganized. There is an urgent need to create such an environment that the entrepreneurs get attracted towards this segment. In India, still the food processing sector is in its developing phase but surely it is a sunrise sector of future.

Research work on-going for biopesticides. The field of biopesticide is still in its nascent stage. In spite of the claimed efficacy, their use, however, has remained very low due to a number of socio-economic, technological and institutional constraints. Increasing awareness of health related effects of chemical pesticides has increased the demand of biopesticides. The researches are being done to develop biochemical pesticides either using plant Extracts and Oils or using Plant/ insect Growth Regulators. Use of various microbes for developing Microbial Pesticides like Bacterial Biopesticides, Fungal Biopesticides, Viral Biopesticides and other Microbial Biopesticides is also being done. They suppress pests either by producing a toxin specific to the pest, causing disease, preventing establishment of other microorganisms through competition, or various other modes of action. Recombinant DNA technology is also being deployed for enhancing efficacy of biopesticides. Novel fusion proteins are being designed to develop next-generation biopesticides. So there are many researches going on and the use of biopesticide is also increasing.

Obstacles faced in your current research. Well, in my current research work the main challenge is regarding the availability of same variety of crop for each experiment. The quantity of the available raw material for research varies time to time. This causes the problem. The method developed for a variety needs to be validated also for other varieties.

SOCIETY FOR SCIENCE & THE PUBLIC BROADCOM MASTERS FINALISTS 2016

R&D YOUNG TURKS Does Freezing Carbonated Water Affect CO2 Coming Out of Solution? Samantha Gaiera This project was designed to find out if freezing carbonated water affected CO2 coming out of solution. The hypothesis was that if carbonated water was frozen, more CO2 would come out of solution than if carbonated water was kept at room temperature for the same amount of time. 80 ml of carbonated water was measured and put into 2 jars. Carbonated water was used because its only ingredients are CO2 and H2O. The pH of the carbonated water was measured and recorded using a digital pH meter. The pH meter was measuring the acidity from the carbonic acid made from the CO2 in the water. The test was placed in the freezer and the control was left to sit out at room temperature. The time of day was noted. After the test froze overnight, it was removed from the freezer and left to melt to room temperature. 24 hours after the initial pH test, the pH of both solutions was recorded. This procedure was repeated for three trials. The average difference between the initial and final pH for the carbonated water that had been frozen was 1.20. The average pH difference for the control was 2.19. This showed that less carbon dioxide came out of solution in the freezer than in the solution sitting out. Although the length of each trial was close to 24 hours, the time in the freezer was not controlled, so that might have affected the results. The results of my three trials showed that letting carbonated water sit out, increases the pH more than freezing and thawing it for the same amount of time. The more carbonic acid in the water, the lower the pH. This suggests that freezing carbonated water slows the amount of CO2 coming out of solution. Source: Society for Science & the Public

Test for energy efficiency of renewable fuels

Sadie Howard The goal of this project was to determine if the energy in renewable fuel is equivalent to the energy in the same amount of non-renewable fuel. Measure the temperature change over time in water as it is heated using renewable fuel and non-renewable fuel. Using a ring stand, stop watch, thermometer, aluminum can, pipette, cotton cordage to absorb fuel, lighter, vegetable oil, and motor oil. The amount of energy in non-renewable fuel proved to be greater than the energy in the same amount of renewable fuel because the motor oil heated the water at a rate of .28 degrees (F)/s, while the vegetable oil heated the water at a rate of.21 degrees (F)/s. However, the motor oil was only greater by 7 hundredths of a degree per second. Repeated trials of non-renewable and renewable fuels show them to be comparable sources of energy, differing by output of 7 hundredths of a degree per second. This means that renewable fuels can provide a reasonable alternative to non-renewable fossil fuels. Sadie R. Howard found that the amount of energy in non-renewable fuel was greater than the energy in renewable fuel by only 7 hundredths of a degree (F) per second. Source: Society for Science & the Public

Chemical Today Magazine | March 2017

LOGISTICS SUPPLY CHAIN CAPABILITIES

Alok Gautam, Country Logistics and Supply Chain Leader, Dow Chemical International Pvt Ltd (Dow India), opens up that the need of the hour for chemical companies is to identify the right balance on responsiveness and efficiency in supply chain operations. He delves into the various sustainable measures that can be taken to make chemical logistics a safer journey.

Chemical Today Magazine | March 2017

MAKING SAFETY A PART

OF ORGANISATIONAL DNA BY SHIVANI MODY Trends and best practices for transportation of hazardous bulk chemicals. The Indian chemical industry has witnessed significant changes postliberalisation. Changing demand patterns and trade trends, increasing logistics costs, rising competitive intensity and focus on Environment, Health & Safety (EHS) and Quality standards are significant trends witnessed in chemical logistics. The need of the hour for chemical companies has been to identify the right balance on responsiveness and efficiency in supply chain operations. This has led to the changing scenarios in logistics and supply chain of chemical industry today. With the origin of Indian imports for liquid chemicals gradually balancing from complete Middle East focus to South-East Asia, the chemical manufacturing and trade activities are more or less spread across the country today. This has given rise to development of East Coast ports (Vizag, Paradip and Cuddalore). Ever-improving road infrastructure, use of railroads to transport chemicals and better awareness and safety standards in movement of hazardous goods are all good signs. We also see in recent years a trend towards significant investments in high-end vehicles for road transportation by Logistics Service Partners (LSPs) to chemical companies. This is really helping in raising the bar on safety and sustainability of operations.

Chemical Today Magazine | March 2017

Common practices include usage of ISO tanks that are extremely safe and feasible mode of transportation. Moreover, a shift to greener modes of transportation saves fuel and reduces CO2 emission as well.

Ensuring proper logistics and transportation of hazardous bulk chemicals in the company. Safety is not just a matter of priority, it’s an inherent part of the Dow DNA. Environment, Health and Safety (EHS) is a critical part of every business decision we make and we would rather forgo a dollar than to risk safety of our people and processes. This is the philosophy with which we operate at every level and the commitment to safety is paramount. We are one of the first Indian chemical companies to propose the use of ISO tanks for local bulk chemical deliveries. We have consistently worked together with our LSPs to use state-of-the-art vehicles and technology to safeguard movement of hazardous chemicals. All our manufacturing facilities are Responsible Care® certified. We have not only adhered to the highest standards of safety ourselves, we have always tried to enable other organizations, whether our partners, vendors or peers in the industry, to do the same. We evaluate all our partners on SQAS system, a standardized assessment to evaluate the quality, safety, security and environmental performance

of logistics service providers. Though in an early phase, we have found the adaptation and response quite encouraging from our partners. Dow India is a founding member of the Indian Chemical Council (ICC) initiatives Responsible Care® to ensure safe and sustainable practices in the industry as well as ‘Nicer Globe’, an online platform that tracks vehicular movement of partner chemical companies and makes available critical information in case of accident or loss of containment.

Growth potential in chemical logistics for the Asia Pacific region. In the past decade the major growth of global chemical industry (~ 3.4 percent) has been driven by Asia Pacific region (~7 percent), led by South-East Asia – naturally, the chemical logistics and supply chain operations in the region have come a long way. Particularly Singapore, China, South Korea, Japan and recently Thailand have emerged as key players, with global giants setting up manufacturing and supply chain capabilities there. West Asia, particularly Middle-East region has been favored over the years due to its geological advantages as well as proximity to developed markets. These advantages still stand and we see the region making a concerted effort to modernize its infrastructure and expand capabilities

across the value chain in chemical manufacturing. Dubai, Jebel Ali and other logistic hubs in the region serve them well and have kept up-to-date in terms of technology and processes. At Dow India, we are poised to benefit from both sides of the regional growth – while we have Map Ta Phut in Thailand for polyols and other assets in South East Asia already providing certain raw materials, our vantage position will be considerably strengthened as SADARA, our joint venture with Saudi Aramco will start production full-steam this year. Another boost for logistics and supply chain will come in form of Goods and Service Tax (GST) roll-out in India. It is expected to simplify the taxation and processes during goods transport considerably in India, which would be a feat. Currently, the resources consumed in coping with complexities of Indian taxes and duties as we transport goods across states are remarkably high. If implemented smoothly, GST will definitely bolster the growth of the sector in Asia Pacific, providing a good growth base for chemical industry overall.

Suggestions for improving road, rail, ship and air logistics for the chemical industry. In India internally, road logistics are used most widely so far – use of airways for goods transport has been increasing exponentially in the past few years, but it is still not as pervasive as developed economies. Another avenue for transport logistics is railways – in India the rail network is over 115,000 km wide, yet the storage and transfer capabilities are not fully developed, so the use of railways to transport chemicals is still very limited. Recent introduction of RO-RO services in rail corridors with busy roads in Maharashtra and Gujarat are a welcome move to improve use of the rail network. So far as the regulations of the modes of transport go, the transport of hazardous materials by any mode is heavily regulated – there are national, state-wise regulations as well as rules and guidelines of transport authorities and governing bodies. The adherence to regulations in India has been a challenge before, but at an industry level, there is much better awareness now and we see a lot of improvement in safety standards and regulatory compliance.

Chemical logistics requirements of emerging markets vs developed markets. It’s a difficult comparison, because the nature of goods manufactured in emerging and developed markets still vary and the

level of infrastructure and demands of the market are in precarious balance. Having said that, there are lessons to be learnt on both sides. In developed markets, the commitment to personal safety, regulatory compliance and quality standards is regarded highly. Emerging markets are getting there in terms of setting processes and achieving compliance standards needed. The developed markets are also focusing more on greener technologies that leave less of a carbon footprint. On the other hand, emerging markets need logistical flexibility in supply, adaptability to different conditions and infrastructure to serve the customers. This has led to great innovation in supply chain and logistics. Today, emerging markets have developed completely new supply chain models that pair frugal innovation – use of low-cost technology for cold storage, optimal use of resources to reap maximum value in goods transport – with availability of labour and use of digital technology. Some of these are easily adaptable in developed markets as well. I do foresee emerging markets growing with increasing demand for chemicals and the logistics sector needs to be ready to respond – we need skilled and trained manpower to handle hazardous and non-hazardous goods transport.

Maintaining sustainability in the supply chain for chemical companies. Sustainability in operations, not limiting only to supply chain, is high on priority for organizations globally. The world needs solutions for big challenges like energy, climate change, water, food, nature and social issues. We, at Dow India are committed to minimizing our footprint and to delivering solutions that help our customers and rest of the society. We have made significant advances in our sustainability journey since launching our first set of decade-long sustainability goals in 1995. Now we are on a journey to fulfill third generation of sustainability goals for 2025. As for sustainable supply chain and logistics operations, in India our focus has been on compliance with the global Dow standards of EHS and elevating the conversation in the industry about sustainability in supply chain. Of course, in operations, the effort is to minimize the footprint and use sustainable fuels, less road and more rails or road-rail-road approach wherever possible.

Managing safety of materials from point to point during transportation in the company.

Customers in India are spread across the length and breadth of the country, this brings in the challenge of distribution for long distances primarily by road. We have rolled out SOPs right from loading points, en-route transportation to unloading at customer locations. For hazardous goods being transported to new location, we conduct Distribution Risk Review (DRR) and the entire route is mapped by experts. It also includes assessment of unloading facility and, if required, includes training to personnel at different nodes. We have imposed restrictions on night driving and work with our partners to ensure drivers are adequately rested on long journeys. GPS tracking of the vehicles is done by LSPs and reports are shared on daily basis to ensure their safe movement on the road. We are taking steps to share properties of chemicals being transported at loading stations, ensuring the info sheets are with drivers. Today, Dow India transports all our hazardous material in ISO tanks, reducing safety risk on the road considerably.

Suggestions to improve policies related to chemical industry global logistics. Globalization has immensely benefitted not only emerging markets but the developed markets as well, if you look at manufacturing and movement of goods. Global sourcing policies and supply chain solutions are at the foundation of many successful multinational conglomerates. The Free Trade Agreements (FTAs), regional and geographic alliances and treaties have played a huge part in facilitating easier movement of goods across countries. India, on its part, is a part of multiple FTAs and regional alliances such as SAARC, BRICS and G20. While these agreements facilitate import-export, on-ground facilitation of supply chain and logistics is also possible through international rail freight and roadway corridors. Many emerging economies have focused on improving their port and airways infrastructure to become logistics hubs for the region. Given India’s vantage position in South Asia, we can also do this – new policies to use river waterways for freight transport, ‘Free Trade Warehousing Zones’ along with building new ports and refurbishing old ones, deployment of advanced technology hand-in-hand with ‘Make in India’ and ‘Skill India’ need to be implemented effectively. This will undoubtedly unleash the potential of India’s logistics and supply chain sector.

Note: To read the full interview, log on to www.worldofchemicals.com/media/interviews/management

Chemical Today Magazine | March 2017

JOBS Operator I - Chemical Company: Ashland Inc Date Posted: 02 February Country: US City: Chatham

Job Description: The Chemical Operator is responsible for some instructions and procedures so as to complete chemical processes in required yield to produce chemical products in required quality.

Officer - Production Company: BASF Asia Pacific Date Posted: 03 February Country: India City: Dahej

Job Description: Objective of this position is to Operate Distributed Control System safely and effectively for production processing. Co-ordinate the start-up, shutdown & normal Operations with Operator.

Chemical Process Technician Company: Evonik Industries AG Date Posted: 03 February Country: Singapore City: Jurong Island

Job Description: Responsibilities of Chemical Process Technician is to operate equipment in the production systems, prepare solutions, monitor certain measuring instruments and equipment, and assist in unloading and loading operations.

Research Scientist - Analytical

Job Description: Research Scientist is Accountable to identify problems, research contributing factors to handle multiple priorities. Analytical method development and validation for impurities using technique like GCMS, GCMS- Headspace, HPLC, GC Characterization of polymer, surfactant using techniques like FTIR, GC-pyrolysis, Gel permeable chromatography, CHNS.

Company: Huntsman Corp Date Posted: 06 February Country: India City: Mumbai

Chemistry Summer Internship Company: The Lubrizol Corp Date Posted: 07 February Country: US City: Brecksville

Job Description: Chemical Synthesis Internship is for the rising junior or senior with a passion for polymer and synthetic organic chemistry. Some experience in preparing and characterizing organic, and/or organometallic, and/or polymeric chemicals (eg organic chemistry lab) is required for this position.

Operator - Manufacturing Company: Merck KGaA Date Posted: 08 February Country: US City: Wisconsin

Products Specialist (Sample Prep) Company: Agilent Technologies Inc Date Posted: 08 February Country: China City: Shanghai

Job Description: Purpose of this position is to produce and purify chemical compounds to meet the demands and requirements of Sigma-Aldrich customers.

Job Description: Products Specialist Own and manage Agilent supplies sample prep products in Greater China region. Work with business operation manager to develop and implement dedicate sales plans, identify and develop new business opportunities to drive business growth.

Operator Company: Ashland Inc Date Posted: 10 February Country: US City: Bartow

Job Description: This position will be responsible for safe and efficient operation of various chemical process equipment including pumps, mixers, charging systems etc. Unloading rail-cars and tank wagons of materials.

Researcher Organic Chemistry Company: AkzoNobel Surface Chemistry Date Posted: 15 February Country: Netherlands City: Overijssel

Chemical Today Magazine | March 2017

Job Description: A key role in showing your capabilities in organic peroxide product and process knowledge and using this knowledge to support the growth of polymer chemistry.

Website: http://www.worldofchemicals.com/chemical-jobs.html

IT IN CHEMICALS CHEMISTRY 4.0

Talk by Dr Kurt Bock, President of Verband der Chemischen Industrie eV (VCI) and Chief Executive of BASF SE.

“CHEMISTRY 4.0: INNOVATIONS FOR

A DRAMATICALLY CHANGING WORLD” To a certain extent, short and medium-term economic fluctuations are normal in a market economic system. But beyond that, in the long run the world of the chemical-pharmaceutical industry is also undergoing fundamental change.

Chemical Today Magazine | March 2017

his is emphasized in the joint analysis by Prognos and Verband der Chemischen Industrie eV (VCI) for the chemical industry to the year 2030. Growth centres are shifting geographically; competition is getting fiercer. Not only the emerging markets of Asia are more intensively investing in research and development. Also industrial nations like the USA and Japan are vigorously driving forward their innovation processes, in order to gain market shares. Against this backdrop, the challenge of maintaining its top position in international competition is greater than ever before for the German chemical industry. Moreover, the globalization and digitalization of value chains change production and business models in the chemical industry. We need to get ready for this. Also the vision of a global climateneutral management style, the political goal of a circular economy in the EU or the Energiewende – energy transition – in Germany bring for us the task to utilize our ability to innovate for these challenges. Many of our member companies are taking an active stance in the face of such challenges. The VCI is currently examining what consequences they can have for our industry. We will present the results of a relevant study in the 2nd half 2017. I am convinced that we once more need to set a course for the future. This is expressed in “Chemistry 4.0” which is much more than another digitalization of the chemical industry. For a qualitative assessment of new things, it is helpful to cast a glance back at the development stages of the industry. In its over 150 year-long history, the chemical industry in Germany has proven more than once that it can successfully renew itself, both in technological and structural terms. This is evident in several periods.

Development stages of the chemical industry in Germany Chemistry 1.0 (1865 and subsequent years) The founding and pioneering time of the industry is strongly characterized by individual inventors who translate chemical findings into large-scale processes. The first chemical companies are founded and grow in this manner. Industrialization stimulates the demand for chemical products like chemical fertilisers, soaps and pharmaceuticals. Natural dyes are replaced by synthetic colours, for example, indigo. The raw material base is provided by reprocessed residues from carbon chemistry (tar) or vegetable and animal

Chemical Today Magazine | March 2017

fats and oils. Production is mainly in the discontinuous batch process. Chemistry 2.0 (1950 and subsequent years) Just under 100 years later, there is a successive changeover to the petroleum distillate naphtha as the raw material base. Naphtha opens up almost unlimited possibilities of new molecules for carbon chemistry. In integrated production over multi-step synthesis, a small number of primary chemicals as building blocks result in an enormous variety of industrial chemicals. Polymer materials from petrochemistry and man-made fibres become everyday products. The strongly growing demand encourages the construction of large plants where production costs are reduced by economies of scale. Big companies dominate the chemical business; they expand their central research departments. End-ofpipe environmental protection in the form of exhaust air filters and waste water purification is established in response to growing environmental problems. Chemie 3.0 (1980 and subsequent years) From the 1980s the increasing use of natural gas and renewables changes the existing raw material base. At the same time, bio-technology broadens the production processes of the industry and enables a new generation of medicines. The close cooperation between basic research in academia and application-oriented research strengthens the innovation ability of companies. The globalization of exports and an internationalization of production sites stimulate growth of the industry. The outsourcing of services and a focus on the core business are parts of the change in large companies. There are rising numbers of mergers and take-overs. Medium-sized enterprises choose an orientation to niches and specialty chemicals. Structural change in the industry also brings the creation of chemical parks. At the same time, the companies make major progress in environmental protection: The industry further cuts emissions by integrating environmental aspects already in production and plant planning. In parallel, product safety increases through a wider examination of substance properties. After this glance back, we should return to the present and also look ahead.

What characterizes the next level Chemistry 4.0 (from 2010)? There are mainly the impacts of digitalization as well as sustainability. They change the interplay between companies at the location Germany across the industries.

We are still at the very beginning. The horizontal linking of value chains is more and more moving to the fore – taking into consideration all three dimensions of sustainability. The intensive use of data and the communication between plants beyond company boundaries bring new chances for efficiency increases and innovative business models in our customer industries. Chemistry is part of this development: Predictive maintenance of plants, pinpoint application of crop protectants and fertilizers in agriculture through “digital farming” or a better steering of logistics with radio tags (RFID chips) – these are just a few examples for fields of application where digitized information is already used to improve cost and resource efficiency. Research and development strongly benefit from the evaluation options for huge volumes of data, particularly where results are elaborated in internationally connected teams. Moreover, with Chemistry 4.0 the industry wants to further develop its function in the value chains. The goal: The industry’s role should not be limited to supplying inputs, the industry also wants to become an established provider of all-round solutions and service packages for customers. Here, 3D printing is an example of a new business model. All this means that Chemistry 4.0 is more to us than just using the chances of digitalization: Sustainability becomes the comprehensive guiding principle and the concept for the future in the actions of the industry. Our initiative Chemie3 stands for this. This includes that we can assume an important function in a circular economy by recovering carbon-containing waste. In the mid-term perspective this also comprises the use of hydrogen from renewable energies in combination with CO2 for basic chemicals production. In this manner, we can concretize the vision of a climate-neutral management style globally. An outstanding topical example: With chemical innovations, the industry has a central role in the fundamental change in mobility through electric drive technology. Chemistry 4.0 stands for the strategy to generate sustainable growth for the industry through innovations at all levels. The ability of companies to continuously evolve has made Germany one of the leading locations worldwide for the chemical and pharma industry. With Chemistry 4.0 we are working to maintain our top position globally – and to make our contribution to the location Germany also in the future. NOTE: Excerpts from a press statement issued by VCI.

PRODUCTS

Seven

formulation solutions specially for tattooed skin

vonik offers seven formulation solutions based on its own raw materials that protect and nurture the skin before and after tattooing. “If the skin is properly prepared and appropriately conditioned after tattooing, it can recover fast,” said Dr Tammo Boinowitz, head of Evonik’s personal care business line. Evonik’s formulations contain active ingredients such as Sphingokine® NP, Skinmimics®, and SK-Influx® V as well as mild surfactants, emollients, and emulsifiers. One example of such a formulation is tattoo preparatory lotion, intended to moisturize the skin adequately before tattooing. The active ingredients from Evonik—including Sphingokine®, Skinmimics®, and Tegosoft® DEC—tauten the skin, stimulate regeneration of the epidermis, and ensure a pleasant, non-oily skin feel. After tattooing, it is important to use a cream or lotion that supports restoration of the skin’s protective barrier. The Evonik active ingredient SKInflux® V is particularly suitable for this purpose. To prevent the colours from fading, the skin needs effective protection against UV radiation. In Evonik’s Daily O/W body lotion SPF 15 for vibrant colours formulation, Tegosoft® DEC increases the solubility of UV filtres. For daily skin care, the lotion also contains the moisturizing emulsifier Tego® Care PBS 6 and Tego® Natural Betaine. Contact: Evonik Industries AG Rellinghauser Strabe 1-11, 45128 Essen, Germany Tel: +49 201 177-01 Email: juergen.krauter@evonik.com Web:www.evonik.com

Chemical Today Magazine | March 2017

Cosmetic Preservative - Effective Concepts

for Product Protection T

he launch of SymOcide® C provides cosmetic manufacturers with an effective and safe alternative to preserve their products. Symrise is offering the cosmetic preservative o-Cymen5-ol (p-thymol) under the brand name SymOcide® C. SymOcide® C is an effective alternative to traditional preservatives. It is odorless and globally approved for use in personal care. Preservatives help to protect personal care products against microbial spoilage, and therefore ensure consumer safety. Regardless of the fact that preservatives are an integral part of cosmetic formulations, current trends call for the replacement of some conventional preservatives for various reasons, such as negative press, consumer perception and regulatory changes. SymOcide® C is globally approved for use in cosmetic products including a positive listing in Europe and Japan as a cosmetic preservative. Its antimicrobial properties are particularly beneficial in Oral Care applications, such as toothpaste. Contact: Symrise AG Muhlenfeldstrabe 1, 37603 Holzminden, Germany Tel. +49 5531 90 0 Email: bernhard.kott@symrise.com Web:https://www.symrise.com

New, innovative

skin-purifying active ingredient available

o protect the skin from the ravages of pollution, Seppic is innovating with Contacticel™, a skin-purifying active ingredient. 92 percent of the world’s population lives in an environment that is too polluted, which causes numerous adverse impacts on the skin, such as early aging, cutaneous malfunctions or over-production of sebum. Contacticel™ is an extract from a little known red algae, Acrochaetium moniliforme which lives in contact with other algae. In association with other microorganisms, it helps to protect its host against outside aggressions. Drawing inspiration from the properties of this algae, Seppic’s new active ingredient offers the skin protection against pollution: in two months, it effectively reduces the sebum of skin exposed to a polluted atmosphere with a visible and lasting result. Contacticel™ is an exceptional skin-purifying agent that works against several pollutants (ozone, microparticles, heavy metals) through its combined properties. After Ephemer™, Contacticel™ is the second active ingredient that Seppic has developed with the innovative technology Celebrity™, which makes it possible here to produce large quantities of biomass from an algae that could not be cultivated or harvested in its natural setting.

Chemical Today Magazine | March 2017

Contact: SEPPIC SA 22 Terrasse Bellini 92800 Puteaux, France Tel: 33 (0)1 42 91 40 00 Email: alexandra.gilbert@airliquide.com Web:https://www.seppic.com

EQUIPMENT CHEMICAL SENSORS MARKET

ASIA PACIFIC

ANALYSIS AND OPPORTUNITY 2015 - 2025

Chemical Today Magazine | March 2017

Overview The significance of chemical sensors as a crucial industrial component has elevated owing to rising environmental risks. The increasing amount of pollutants released into the air has necessitated the demand for chemical sensors. Advantageous applicability of sensors in the analyzing chemical composition of varied samples is influencing adoption of chemical sensors. Higher order orthogonal sensors and chemical sensing array are key trends that are shaping up the global market. Low cost and portable nature of chemical sensors is also expected to fuel the growth of chemical sensors market during the forecast period. Besides environmental benefits, the use of chemical sensors to quantify analytes in chemical industrial processes is also witnessing an increase. Research labs, industrial processes & defense sector, and healthcare operation are using chemical sensors as advanced tools, which in turn, is driving the demand in the global chemical sensors market.

Asia Pacific: A Key Region North America and Europe are the leading regions in terms of overall demand for chemical sensors. Adoption of chemical sensors is expected to grow rapidly in APAC over the forecast period. The APAC chemical sensors market is likely to emerge as the fastest growing market with a double-digit CAGR over the forecast period 2015-2025.The concerning pollution levels in China, India and other APAC countries are also driving the demand for chemical sensors. Low prices, flexible applications and speedy technological implementations are fuelling the demand for chemical sensors in the APAC market. The APAC chemical sensors market forecast seems promising, owing to the rising usage of chemical sensors in industrial safety operations and environmental monitoring programs.

Factors Expected to Shape the Market In APAC, chemical sensors can be termed

as ideal components, having analytical functions, which can help prevent the unwanted output of several processes and monitor the health of the atmosphere. The factors impelling the onward growth of APAC market for chemical sensors include, • Growing usage of chemical sensors in indoor monitoring and homeland security applications. • Pervasive usage in the pharmaceutical, chemical, defence, security, food, biomedical, and clinical processes. • Integrations of chemical sponsors in electronics, computers, processing tools and novel designs of upcoming industrial machines. The manifestation of advanced technology for the production of cost-effective, miniaturized and portable chemical sensors, capable of continuous and static measurements in the remote environment, is a latent growth factor in the APAC chemical sensors market. On the other hand, the growth of chemical sensors market in APAC region is facing challenges that are derived from the resulting output of the use of chemical sensors. The three most crucial restraints of chemical sensors market include,

function and thereby, regard the chemical sensors as useless.

Market Segmentation Chemical sensors are integral components of products designed to analyse the chemical composition of a sample in an industry with the help of a particular technology. Hence, the global market for chemical sensors can be segmented on the basis of,

Product (Particulate Type) • Gas • Liquid • Solid

End-Use Industry • Medical • Automotive • Healthcare

Incorporated Technology • Electrochemical • Biochemical • Optical • Electrical • Electromechanical

Selectivity

• Thermometric

Chemical sensors are selective in nature. For example, biochemical sensors can be applied only in biochemical process, and their use in other processes can deliver inefficient output.

• Others

Sensitivity Upon continuous exposure to haphazard materials and chemicals, the sensitivity of the sensors will degrade. This will result in the persisting replacement of chemical sensors, and create a despise environment for the end-users.

Reversibility The design of any chemical sensor makes it unidirectional. However, the reversible chemical reactions occurring in an industrial process may alter the monitoring

Competitive Landscape The key companies shaping up the competitive landscape of the global chemical sensors market, including APAC region, are Abbot Laboratories, Nova Biochemical Corp., Denso Corp., Hoffmann-La Roche, NGK Spark Plug Company, Emerson Process Management, among others. In 2015, the leading multinational sensor and semiconductor manufacturer, Austria Mikro Systeme (commonly known as ams AG) acquired the CMOS sensors from NXP Semiconductors as a strategic measure to expand their existing environmental sensor technologies. Mergers as such illustrate the expansion of the global chemical sensors market size. Source: Future Market Insights

Chemical Today Magazine | March 2017

EQUIPMENT DISPENSING EQUIPMENT

HOW TO CHOOSE THE RIGHT DISPENSING EQUIPMENT? W

ith the advent of disposable medical equipment, the need for fast, reliable manufacture has increased considerably. The use of various assembly techniques has called for a number of different joining methods – primarily ultra-sonic welding, solvent welding and adhesive bonding. The latter category has some distinct advantages – in particular, the ability to provide easy application and to offer cure on demand. So, just how do you handle high volume production – while achieving accurate dispensing at a cost efficient price? The answer is automated application equipment. And it offers some real benefits. First, using application devices means only the required amount of product is used for each job. Compared with manual applications, savings of up to 50 per cent can frequently be achieved. And it is those kinds of savings that will gladden the heart of any financial director! Secondly, automatic equipment ensures the adhesive can be applied with precision. But beyond that, accuracy can be achieved at speeds far beyond even the fastest of manual efforts. For example, if a manufacturing facility sets a production target of one million components a year, that could involve a throughput of one unit every five seconds. Applying an adhesive by hand at that rate is just about impossible – let alone doing it with extreme accuracy. Next, automation will allow the product to be dispensed at a specified time, in the necessary volume, in a defined position, and with constantly repeatable accuracy. Needless to say, such results would be impossible to achieve with even the most diligent manual application. Lastly, application equipment allows a cleaner and safer working environment. Automation removes operator contact with the adhesive and significantly reduces the possibility of accidental misuse of the product. So, the case for automated application is considerable – but just what should you consider when choosing equipment for adhesives?

Chemical Today Magazine | March 2017

Chief considerations Fundamentally, there are three important considerations in selecting dispensing equipment - viscosity, dispense pattern and adhesive type. First, the viscosity of the adhesive will determine the type of equipment required. To state the obvious - the thicker the adhesive, the greater the power needed to dispense the product. Brands such as Loctite come in a variety of viscosities to suit different needs. The dispense pattern can vary from single to multiple spots, linear beads to circular coating and include dot sizes from 0.001ml per shot. On the other hand, screen printing - where the adhesive is squeezed through a fine mesh of the required shape - is an effective method of dispensing product on a large, flat surface. If the adhesive needs to be applied to the bore of a circular object, a rotaspray arrangement would be needed. This process involves measured adhesive being thrown by centrifugal force from a rotating cup to create a level coating on the inner surface of the part. Obviously, the type of equipment type will depend on the kind of adhesive being applied. For example, an Ultra Violet adhesive (a favourite among medical device producers) must be dispensed from a container and via tubing that restricts natural light. Any light falling on the adhesive before it reaches the surfaces to be joined will bring about premature curing.Anaerobic products (those that cure on metal surfaces in the absence of oxygen) demand equipment that doesn’t include metal and where they can reside in a container that allows air to be present. So, with all of that mind, equipment suppliers will need to discover the answers to a number of pertinent questions before being able to provide advice. • What type of adhesive is planned? • What is the size and shape of the parts to be bonded and/or sealed?

• How do the parts proceed along the assembly line? • What is the production rate? • At what stage of the production process will the adhesive be applied? • How long before the parts need to be handled or tested? Matching the needs Most manufacturers provide dispensing equipment ranging from simple hand operated guns to fully automated machines suitable for integration into production lines. When low viscosity products are involved off-the-shelf hand applicators are generally adequate. These low-cost handguns can be used with anaerobic, acrylic and silicone adhesives. However, they are not suitable for cyanoacrylate (‘instant’) adhesives. Some models dispense a continuous bead, while others apply single precise drops. The quantity dispensed by the hand trigger can be varied - with most common amounts being between 0.005 ml and 0.03 ml. Cartridge-packed adhesives can be dispensed by hand operated skeleton guns or pneumatic cartridge guns. In the latter case, the flow is regulated by manual control of the air supply. Foot operated versions of these guns are often available, too.

More demanding Semi-automatic systems dispense adhesive in precise doses while permitting control over both when and where the bead is applied. Such units are generally activated by means of a hand operated micro switch, although foot controls are also available. This equipment generally comes with a selection of valves to handle different adhesive types. Where UV adhesives are used, a suitable light source is required. Where lower volume dispensing is needed, a simple light probe will provide sufficient UV light to affect a cure. Where throughput is more substantial, an oven designed for UV adhesives might be a better proposition.

The key is matching the Ultra Violet light wavelength and intensity with the adhesive that is to be used. Semi-automatic systems are most commonly seen in manufacturing plants where medium to high volume repetitive work is demanded.

Top of the range

The answer depends on the type of adhesive being dispensed. An anaerobic will only cure when it comes into contact with a metal and when air is excluded from the joint. Therefore, unless metal has contaminated the nozzle or pipe, the adhesive will remain in liquid form.

In situations where fully automatic adhesive application is appropriate, equipment suppliers will usually design and build systems to meet specific requirements. These can either be integrated into existing production procedures or be completely self-contained. These purposebuilt systems can include features such as dispense monitoring facilities, low level tank warning signals and equipment failure alert.

So, no problem there.

Some common concerns

Two part adhesives do not cure until mixed together. Where mixing takes place in the nozzle, it is simply a matter of replacing it. Alternatively, an automatic purge cycle can be fitted which will clear the nozzle on a regular basis.

Users are sometimes concerned about possibility of the adhesive clogging up nozzle of their system. What occurs, example, during a tea break or over weekend?

the the for the

Cyanoacrylates (instant adhesives) cure when they come into contact with airborne moisture. If the adhesive does solidify at the dispensing end of the equipment, then the quick and inexpensive answer is to change the nozzle. Otherwise, the solution is to use special nozzles fitted with plastic liners to improve resistance to curing. Again, no difficulties.

Once more, no problem if the equipment is correctly set up. Making efficiencies There is no doubt that application equipment is a highly cost effective, clean and accurate way of dispensing adhesives. And the equipment can serve to dispense product to a wide selection of components. But, the equipment must be the right unit for the job or jobs in hand. And, generally speaking, there are many advantages to having the adhesive manufacturer also supply the equipment. When you are considering the use of dispensing equipment, the first step is to talk to an adhesives manufacturer. The technical specialists there will need to know what type of applications are involved, the production needs and the adhesive under consideration. Once those questions have been answered, it should become obvious just what kind of unit is best suited in order to make the processes simple, efficient and commercially viable. Contact:

Henkel Adhesives Technologies India Pvt Ltd Email: marketing.ag@henkel.com

Chemical Today Magazine | March 2017

EQUIPMENT

Ecoflux* Corrugated Tube Heat Exchangers for energy efficient heat transfer processes.. Ecoflux* Corrugated Tube Heat Exchangers (CTHE), flagship product of HRS Process Systems Ltd. is an innovative and energy efficient solution for various chemical industry applications like heating, condensation, cooling, chilling, reboiling and heat recovery.

Corrugated Tube Heat Exchangers for energy efficient heat transfer processes

The development of corrugated tube is perhaps the most exciting advancement in heat transfer technology. Ecoflux* CTHE incorporates corrugated tubes instead of smooth tubes which enables different flow regimes. This boosts the heat transfer by avoiding fouling due to formation of boundary layers with minimum increase in pressure loss.

coflux* Corrugated Tube Heat Exchangers (CTHE), flagship product of HRS Process Systems Ltd is an innovative and energy efficient solution for various chemical industry applications like heating, condensation, cooling, chilling, reboiling and heat recovery. The development of corrugated tube is perhaps the most exciting advancement in heat transfer technology. Ecoflux* CTHE incorporates corrugated tubes instead of smooth tubes which enables different flow regimes. It is designed in various patterns to suit a range of processes. The company can design & supply Ecoflux* CTHE in wide range of material of construction. Ecoflux* CTHE brings significant enhancement in heat transfer performance with long running times due to turbulent flow. Using Ecoflux* CTHE ensures minimised fouling, reduced maintenance costs and minimum spares requirement additionally high response to Clean-in-Place (CIP) without disassembly. Contact: HRS Process Systems Ltd 201/202 Karan Selene, 851 Bhandarkar Institute Road, Pune 411004, India

Ecoflux* CTHE is designed in various patterns like K – Series, DT - Series, MI- Series, ASSeries to suit a range of processes. HRS has expertise to design & supply Ecoflux* CTHE in wide range of material of construction likeTel: Titanium, Tantalum, Duplex, Hastelloy, Copper, 020 25663581/82/ 66047894 Cu-Ni alloys along with variants of stainless steel. Email: info@hrsasia.co.in HRS Process Systems Limited 201/202 Karan Selene, 851 Bhandarkar Institute Road, Pune -411004 Tel: +91 (20) 66047894/95, 2566 3581 / 82 Fax: +91 (20) 2566 3583 Email: info@hrsasia.co.in Url: www.hrsasia.co.in CIN: U29198PN2003PLC017846

Medicament mixer for simple to complex reactions

lanetary Mixer has facilitated a wide range of operations from the production of vast quantities of products and handling simple mixtures to complex reactions, which involve high internal pressure and controlled temperatures. The company offers these in stirrer designs and generate orbital rotation, just like a beater covers every point of the bowl, to provide efficient mixing results. Planetary Mixer has use for manufacturing of medicament, ointments, cosmetics: cold creams, hair dye cream, conditioners, lotions, gels, shampoo, and toothpaste etc. It has advanced drive heads can be raised and lowered by using a manual, hydraulic or electro mechanical means. The bowls are easily removable and facilitates the users in applications requiring remote discharge and cleaning. Jacketed Bowls are provided as an optional attachment.

Contact: ABS Pharma Equipments Gala no.-22/B, Star Industrial Estate, Naikpada, Waliv, Vasai (East), Dist. Palghar-401208., Maharashtra, India. Mobile : +91-9890204833 Email: anupnath326@rediffmail.com Web: http://www.abspharmaequipments.com

Chemical Today Magazine | March 2017

Web: www.hrsasia.co.in ASME ‘U’ Stamp Certified Company

Vacuum stainless steel mixing tank with agitator, mixing vessels

acuum mixing vessels is a container with an agitator for mixing, dispersing and reaction of different materials in chemical production. It is widely used in chemical, food, pharmaceuticals, resin, coating, paint, printing ink industry. It can be either dished end type or flat lid type, with level gauges, temperature detectors and display device. Usually, it has manhole, sight glass, feeding inlet, discharging outlet and spare openings. For different production process and reaction materials, the company will have different designs and configurations, mainly displayed on its shape, overall size, sanitary requirement, seal effect, with condenser, heat exchanger, pressure sensor, temperature sensor and load cell. Various agitators and discharging modes are available for option. Contact: Shree Bhagwati Machtech India Pvt Ltd. 9/A, Bhagyoday Estate, Ajod Dairy Road, Rakhial Industrial Area, Ahmedabad - 380 023, Gujarat, India Tel:+ 91 79 22770475 / 22730075 Email:response@multipackfillingmachine.com Web:http://www.storagetankindia.com

PP, HDPE pickling tanks with fume scrubber for steel plants

PPCPL offers pickling tanks for steel industries for pickling process of MS and stainless steel coils/bars/pipes. These tanks are manufactured from PP and HDPE. Thermoplastic pickling tanks are offered with specially designed lip type hood for fume collection from the sides of the tank. This kind of hood is suitable for the batch pickling operation for continuous pickling operation. Hood can be offered Top mounted and of any suitable shape. EPPCPL also offer pickling tanks with suitable hood and fume scrubber with a centrifugal exhaust fan. Its application include in coil pickling lines, surface treatment plants, hot dip galvanizing plants, stainless steel pickling plants, wire pickling lines, electroplating/anodizing plants, pipe pickling plants, metal finishing industries, steel cold rolling mills etc. The advantages are it has good insulating qualities, chemical & weather resistance, light weight and is easy to install. Contact: EPP Composites Pvt. Ltd. Plot No. 2646 Kranti Gate Main Road, GIDC Lodhika, Kalawad Road Metoda 360021, Rajkot, Gujarat, India. Tel: +91 70433 34762/+91 02827-287059/60 Email: kuwarjoshi@epp.co.in Web:www.epp.co.in

Chemical Today Magazine | March 2017

EQUIPMENT

Highly efficient sodium hydrosulfide (NaHS) production system

he Bionomic NaHS modular production system utilizes multistage gas absorption devices in a two-step process. This offers extremely efficient sodium hydrosulfide solution production using hydrogen sulfide and sodium hydroxide as the feedstocks. The Bionomic process consists of two absorption and reactor stages operating in series each incorporating a two stage hydrogen sulfide absorber arrangement that can achieve highly efficient 99.99 percent conversion of the hydrogen sulfide to NaHS. Each stage utilizes a unique design jet venturi followed by a packed absorption column situated over a reaction tank. This two stage combination multi-absorber set up combined with close temperature controls enables the process to run at optimum uniform product temperatures ensuring high quality NaHS production and reduced hydrogen sulfide off gassing. Precise controlled feeding of reactants with close temperature controls also ensures intermediate sodium sulfide concentrations are also held to within a specific range to eliminate unwanted precipitation. Contact: Bionomic Industries Inc. 777 Corporate Drive Mahwah, NJ 07430, USA Tel:800-311-6767/201-529-1094 Fax:201-529-0252 Email:sales@bionomicind.com Web:https://www.bionomicind.com

Introducing line of dry vacuum pumps

ash Dry-Pro series is a remarkably simple, yet sophisticated, reliable, and highly efficient line of dry vacuum pumps. The dry and contact free operation requires no lubrication in the pumping chamber. The result: no process contamination and no pollution caused by the pump operation. Nash Dry-Pro pumps can handle corrosives, organics, inorganics and solvents because of its oil-free, non-contacting screw design and are ideal for pharmaceutical and fine chemical applications. The pumps featuring high vapour and liquid tolerances, are easy to service, and have a long service life - the low rotational speed ensures low noise and low vibration operation. The shafts and screws are one solid piece, allowing for safe, problem-free design that eliminates corrosion between the screw rotor and shaft that can occur in other pump designs. Contact: Gardner Denver Nash LLC Alta Vista Business Park, 200 Simko Blvd, Charleroi PA 15022, USA Tel: +1 724-239-1500 Fax: +1 724-239-1502 E-mail: nash@gardnerdenver.com Web: http://www.gdnash.com

Chemical Today Magazine | March 2017

New Programmable, Corrosion Resistant, Stirring Hot Plates

orrey Pines Scientific announces its new EchoThermâ&#x201E;˘ programmable corrosion resistant digital stirring hot plates for use with aggressive chemicals in environments where other stirring hot plates would be quickly destroyed by vapours or spills. The EchoThermâ&#x201E;˘ Model HS70 programmable stirring hot plates are designed to be purged using an inert gas through a fitting on the rear of the chassis. Purging provides a positive pressure inside the unit to prevent corrosive gasses from entering the chassis and attacking the electronics or stirring mechanism. These units feature 10-programme memory with 10 steps per programme, temperature ramping, RS232 I/O port, membrane keyboard, and full function liquid crystal display where all parameters are continuously visible. Temperature control is by PID software. Contact: Torrey Pines Scientific, Inc. 2713 Loker Avenue West, Carlsbad, CA 92010 USA Tel:+1 760 930 9400/+1 866 573 9104 Fax:+1 760 930 9480 E-mail: info@torreypinesscientific.com Web:http://www.torreypinesscientific.com

ICP-OES instrument with superior analytical performance

eledyne Leeman Labs Prodigy7 ICP-OES instrument has superior analytical performance, which does not have to be traded off for any reason including price. While the Prodigy7 offers all of the advanced capabilities some laboratories require none of them have to be purchased up front if not needed. They can be easily added later if needs change. With large format, advanced CMOS array detector generating true simultaneous measurement, full wavelength coverage from 165 nm - 1100 nm, 500 mm-low stray light optics and full spectral access to capture the entire wavelength spectrum in a single reading, the Prodigy7 will solve your ICP-OES needs. ICP-OES is used for a wide range of applications in the following industries such as environmental, oil analysis, pharmaceutical, food, petrochemical, mining, biofuels etc. Contact: Teledyne Leeman Labs 110 Lowell Road, Hudson, NH 03051, USA Tel:603-886-8400 Email:LeemanInfo@teledyne.com Web:http://www.teledyneleemanlabs.com

Chemical Today Magazine | March 2017

EQUIPMENT

New smaller, faster handheld Raman spectrometer for material verification

etrohmâ&#x20AC;&#x2122;s Mira M-3 is the new handheld Raman spectrometer. Barely larger than a smartphone, the Mira M-3 enables true single-handed operation. The new Raman spectrometer meets the regulatory requirements of FDA CFR 21 Part 11 making it the preferred solution for fast, straightforward QC in the pharmaceutical industry. Operating Procedures can be customized on the Mira M-3. Routine users start their measurements at the push of a button to verify the identity of materials with a pass/fail result in a few seconds. Dedicated sampling attachments such as a Vial Holder (for powders and liquids) and a Tablet Holder (for tablets and pills) are part of the Mira M-3. Point-and-shoot attachments are also available for contact measurements through barriers (eg glass bottles). The Mira M-3 is fully compliant with FDA 21 CFR Part 11 providing multilevel access control, audit trails, secure electronic records and other features to exceed regulatory requirements.

Chemical Today Magazine | March 2017

Contact: Metrohm USA Inc 6555 Pelican Creek Circle, Riverview, FL 33578, USA Tel: 866-638-7646 Email: info@metrohm.com Web:https://www.metrohm.com

March Issue

Sector Focus Chemicals Section Cosmetics

• Antiperspirants • Deodorants • Haircare Chemicals • Skincare Chemicals • Suncare Chemicals • Oralcare Chemicals • Color Cosmetics • Anti-Oxidants •Emulsifiers • Foaming Agents • Anti-Wrinkle Agents • Emollients • Preservatives • Waxes

Soaps & Detergents

• Laundry Aids • Dishwasher Detergents • Household Cleaners • Chelating Agents • Detergent Raw Materials • Liquid Detergents • Bleaching Agents • Disinfection Agents

•Laundry Additives • Anionic Detergents •Cationic Detergents

Surfactants

• Nonionic Surfactants • Anionic Surfactants • Cationic Surfactants • Amphoteric Surfactants • Polymeric Surfactants

Enzymes & Harmones

• Textile Enzymes • Leather Enzymes • Bakery Enzymes •Brewery & Distillery Enzymes • Animal Feed Enzymes •Effluent Treatment Enzymes •Detergent Enzymes •Pulp & Paper Enzymes •Personalcare Enzymes •Plant Hormones •Human Hormones

Equipment Section Chemical Process Equipment

• Agglomerators • Agitators • Air Strippers • Blenders • Blowers • Chillers • Compressors • Condensers • Cooling towers • Crushers • Crystallisers •Distillation Equipment • Drivers • Dryers • Dust Collection Equipment • Evaporators • Feeders • Filtration Equipment • Fractionators • Granulators

• Heat Exchangers • Incinerators • Industrial Ovens • Mixing Equipment • Mills • Pipes • Precipitators • Pressure vessels • Pumps • Reactors • Shredders • Screening Equipment • Scrubbers • Sedimentation Equipment • Seperation Equipment • Storage Tanks •Valves • ventilators • Air Handlers • Autoclaves •Bioreactors • Blow Molding

April Issue

Sector Focus Chemicals Section: • Paint & Coatings • Propellants • Gas Treatment • Aerosols • Industrial Gases

Equipment Section: •

Chemical Process Equipment

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Chemical Today Magazine | January 2017

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