Time Contact Diciembre 2018

Page 14

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VISUALIZAN LA TRISTEZA EN EL CEREBRO SADNESS IS VISUALIZED IN THE BRAIN Investigadores de la Universidad de California en San Francisco, realizaron un estudio a 21 personas en el que determinaron que la tristeza genera una comunicación intensa entre las zonas cerebrales de la emoción y de la memoria. 13 de los 21 pacientes compartían la misma red en el cerebro, es decir, en el cerebro de estas personas los autores notaron un vínculo entre la tristeza y un circuito neuronal particular que conecta la amígdala, que lidia con fluctuaciones emocionales, con el hipocampo, que ayuda a almacenar recuerdos. Researchers from the University of California in San Francisco conducted a study to 21 people in which they determined that sadness generates intense communication between areas of the brain where emotions and memory are stored. Out of 21 patients, 13 of them shared the same network in their brain, that is, all these people were noted to have developed a connecting link between sadness and a certain neural circuit that connects the Amygdala, which performs a primary role in decision making and emotional responses, with the Hippocampus, which is associated mainly with storing long term memory. «

LA REGULACIÓN DE LOS RITMOS CIRCANDIANOS, ÚLTIMO AVANCE CONTRA EL CÁNCER

LATEST DEVELOPMENTS AGAINST CANCER, THE REGULATION OF CIRCADIAN RHYTHMS Un grupo de científicos estadounidenses ha demostrado que la regulación de ritmos circadianos podría tener un papel crítico en la lucha contra ciertos tipos de cáncer de hígado. Estos ritmos son un ‘reloj’ interno; regulan el sueño, el metabolismo y otras funciones vitales las 24 horas y operan en todas las células. En el estudio, lograron inhibir el avance del cáncer de hígado en un ratón, manipulando su ‘reloj circadiano’ a nivel molecular. Luego los investigadores confirmaron el hallazgo en las muestras del tejido humano. El equipo identificó una proteína defectuosa que inhibía la expresión de un factor clave de transcripción circadiana y bloqueaba la capacidad de los supresores tumorales de seguir su ‘ritmo celular’ de 24 horas. Cuando los investigadores forzaron a las células tumorales a volver a producir la proteína circadiana defectuosa, las células tumorales morían. A group of US scientists have demonstrated that the regulation of Circadian Rhythms might play a key role in the fight against certain types of liver cancer. Circadian Rhythms are basically a 24-hour internal clock that regulate sleep metabolism, another vital functions operating in all cells. In their study, scientists were able to inhibit the progression of liver cancer in a lab mouse, by regulating it´s “circadian clock” at a molecular level. Later, scientists were able to confirm findings in samples of human tissue.The team was able to identify a defective protein which inhibited the expression of a key factor of the circadian transcription and blocked the capacity of tumor suppressors to continue their celular rhythm of 24 hours. As scientists forced the tumoral cells to produce circadian defective protein again, these began to die. «

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