MEDICAL SCIENCES
Systolic Time Intervals in Clinical Heart Failure Left ventricular (LV) systolic function evaluation is based on ejection fraction assessment. Due to the great sensitivity of the examination, systolic time intervals (STI) are ideally suited to studying the effects of pharmacologic agents on the heart. By knowing the values of STI in ischemic heart disease (IHD) LV systolic dysfunction can be identified. Additionally, this method could have impending applications in the management of IHD. Smitha P S, PhD Scholar, Dept of Physiology, Sri Devaraj Urs Academ of Higher Education and Research Kaviraja Udupa, Faculty, Dept of Neurophysiology, NIMHANS Vinutha Shankar, Professor and Head of Dept of Physiology, Sri Devaraj Urs Academy of Higher Education and Research
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urrently, cardiovascular diseases (CVD) is the leading cause of mortality in India. Ischemic heart disease (IHD) and stroke are the predominant causes and are liable for >80 per cent of CVD deaths. The quality of cardiovascular care in timely detection and variation in CVD treatment to halt the progression of the disease is of paramount importance. Systolic time intervals (STI) measurement provides a temporal representation of the stages of the cardiac cycle that occur sequentially and are physiologically impacted by factors such as heart rate, preload, afterload, and myocardial inotropic condition. Hence, the addition of easily available techniques like STI measurements in primary and secondary healthcare settings in India along with routine standard investigations is the need of the hour.
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A SI A N H O S P I T A L & H EA LT HCA R E M A N AGE M E N T
Figure 1: Study flow IHD: Ischemic heart disease; MI: Myocardial infarction; ACS: Acute coronary syndrome; STEMI: ST-elevation MI; NSTEMI: Non-STEMI; PCI: Percutaneous coronary intervention; STI: Systolic time intervals; PEP: Pre-ejection period; LVET: Left ventricular ejection time; QS2: Total electro-mechanical systole.
IS S UE - 58, 2022
