Pharma Focus Asia - Issue 38

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RESEARCH & DEVELOPMENT

OCULAR DRUG DELIVERY PERSPECTIVE CURRENT CHALLENGES AND OPPORTUNITIES

Efficient drug delivery to eye remains a major challenge for the pharmaceutical researchers worldwide due to the number of barriers offered by this sensitive organ namely, static barriers dynamic barriers and metabolic barriers. Bypassing these barriers to reach the target site is the key to optimal therapeutic effect of ocular drugs. As the anatomy and physiology of each barrier is unique the ways to bypass them should also be different. This review summarises the various challenges and newer trends in the ocular drug delivery. Reshal Suri, Pursuing PhD, Pharmaceutics, Jamia Hamdard Sarwar Beg, Assistant Professor, Department of Pharmaceutics School of Pharmaceutical Education and Research, Jamia Hamdard Kanchan Kohli, Head, Department of Pharmaceutics School of Pharmaceutical Education and Research, Jamia Hamdard

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P H A RM A F O C U S A S I A

ISSUE 38 - 2020

A

s per the estimation of a Forbes analysis (2013), around US$5 billion is spent by large pharmaceutical companiesfor a single drug approval. Despite immense increase in the research expenditure and number of compounds in the development phase, the rate of approval of these compounds is fairly less due to the lack of drug efficacy. This innovation drought is also a major concern of ophthalmic care


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