EL AMPLIO MUNDO DE LAS TETRACICLINAS
CALIFICACION
THE BROAD WORLD OF THE TETRACYCLINES
_________
CELI ROMERO CELIA ELENA
10
UNIVERSIDAD TECNICA DE MACHALA, ECUADOR, elenaceliromero@gmail.com
ABSTRACT
producing
Tetracyclineas natural
are
or
a
set
of
semisynthetic
antibiotics,
derived
from
different
species
of
the
polypeptide
chain”. (2) “In additiom to this mechanis, tetracyclines can chelate the magnesium
necessary
for
Streptomyces. They share the
ribosomal binding to occur and
same
inhibit some bacterial enzyme
antmicrobial
spectrum,
tetracycli naphthacene nucleus,
systems,
toxicity
phosphotylation”. (2)
and
mechanism
of
action, varying in what is the pharmacokinetic profile. (1) Tetracyclines
are
including
oxidative
“Chlorotetracycline, bromotetracycline,
broad-
oxytetracycline
and
the
spectrum bacteriostatic agents,
tetracycline itself belong to this
having a effect on a wide variety
group of antibiotics. They all
of
share a common formula”. (2)
microorganisms,
them
the
preference
making
antibiotics
of
humans
and
in
animals. (1) “Biosynthetic tetracyclines block the
synthesis
preventing
of
the
proteins,
binding
of
Keywords:
Tetracyclines,
antibiotics, quality control RESUMEN Las tetraciclinas son un conjunto de
antibióticos
naturales
transfer RNA, which carries the
semisintéticos,
amino acid, with the ribosomal
distintas
units, that are mounted on the
Streptomyces.
mRNA
mismo espectro antimicrobiano,
chain
and
that
are
derivados
o
especies Comparten
de de el