15 minute read

a trailblazing Mix / crisol pionero

Playing Chicken with Glyphosate

from the previous page biochemical cells use and interact with.” During this synthesis, modification of a glycine analogue such as glyphosate will alter the physical and chemical properties of proteins and alter their “folding, stability, activity, and ultimately, the function of the protein”1 .

Advertisement

As a glycine analogue, glyphosate is a major factor in carcinogenesis2. “roundup was able to replace and work synergistically with estrogen, which is required for growth of breast cancer cells.” it did so by being incorporated into polypeptide chains during protein synthesis. Of the 1,550 genes analyzed, the expression of 680 was either increased or decreased. this was found in roundup formulations down to 0.00023% dilution of the commercial formulation:

“Alteration of estrogen-regulated gene expression in human cells induced by the agricultural and horticultural herbicide, glyphosate”.3

In September of 2019, the journal Frontiers in Genetics published “Glyphosate Primes Mammary Cells for tumorigenesis by reprogramming the Epigenome in a TET3Dependent Manner.” There is a heightened oncogenic response in mammary cells via the TET pathway (9/27/19). In the 2012 Gilles-Eric Seralini two-year study of glyphosate, he and his team found that female rats fed glyphosate “developed large mammary tumors almost always more often than and before” rats that were in the control group4 .

It didn’t take long to find studies that evidenced adverse health effects from “pure” glyphosate on human breast cells. the effects were found in human hormone-dependent breast cancer. But, risk becomes complicated when science is compromised by governmental agencies. Lessons are hard to cull from studies when those studies follow methodologies that are lacking, when rigor is compromised by financial gain. Knowledge about cause and effect is sucked into agribusiness’ black hole and risk becomes part of our diet!

Near the end of 2015, Jason Best, writing for TakePart, concluded that “it doesn’t take more than five minutes poking around on Google or WorldCat to begin turning up fairly recent studies in peer-reviewed scientific journals that include sentences like “a growing body of knowledge suggests the predominance of endocrine disrupting mechanisms caused by environmentally relevant levels of exposure to glyphosate-based herbicides.” For instance, various studies from South America, Europe, and the united states have evidenced low doses of glyphosate altering the development of the female reproductive tract, acting as “reproductive toxicants.” it affects the differentiation of ovarian follicles and the uterus. this exposure can happen prior to puberty or during gestation5. Another study by samsel and Seneff was published in 2016 in the Journal of Biological Physics and Chemistry that found (...) glycine, the smallest amino acid, has unique properties that support flexibility and the ability to anchor to the plasma membrane or the cytoskeleton.

Glyphosate substitution for conserved glycines can easily explain a link with diabetes, obesity, asthma, chronic obstructive pulmonary disease (COPD), pulmonary edema, adrenal insufficiency, hypothyroidism, Alzheimer’s disease, amyotrophic lateral sclerosis (ALS),

Parkinson’s disease, prion diseases,

Lupus, mitochondrial disease, non-

Hodgkin’s lymphoma, neural tube defects, infertility, hypertension, glaucoma, osteoporosis, fatty liver disease and kidney disease (“Glyphosate pathways to modern diseases V: Amino acid analogue of glycine in diverse proteins”.) A recent study from scientists in England, France, Italy and the netherlands found that the same mechanism of action by which glyphothomas Block Middlefield, OH sate kills weeds and plants also kills or alters the composition of the gut microbiome in animals that include the bacteria and fungi that impact immune functions in their bodies. the analysis of gut and blood biochemistry “revealed evidence that the animals were under oxidative stress, a condition associated with DNA damage and cancer” and that glyphosate interferes with the shikimate biochemical pathway in gut bacteria, similar to its actions in weeds and plants6 .

NOTAS/NOTES

1. Wikipedia 2. see Joaquin, July 2019 3. human and experimental toxicology, 2007 4. see dr. rosemary Mason, 10/10/18 5. us right to Know, 8/12/20 6. us right to Know, 1/27/21

Jugando “Gallina”con Glifosato

viene de la vuelta productos y células bioquímicas que finalmente utilizan y con las cuales interactuarán”. Durante esta síntesis, la modificación de un análogo de glicina (como el glifosato) alterará las propiedades físicas y químicas de las proteínas y alterará su “plegamiento, estabilidad, actividad y, en última instancia, la función de la proteína”1 . concluye en la pág. 26

MI PERIPLO A UOP

Crisol Pionero

Hace 57 años me bajé del autobús Greyhound en el centro de Stockton; era estudiante del primer año en el Raymond College de la UOP, la primera de las nuevas escuelas autónomas dentro la universidad. Nunca había estado en el campus. De hecho, nunca había estado a 100 millas al oeste de mi casa en San Antonio, Texas ¡Nunca había visto una montaña!

No solo era el único latino en mi clase de primer año, era el único hispano en la universidad. no fue hasta mi segundo año que la universidad matriculó a su primer estudiante afroamericano. No solo era el único latino, sino también era “importado” de Texas. En otras palabras, la universidad no tenía hispanos del condado san Joaquín o siquiera de California. Quizás igualmente sorprendente, en ese momento no encontré nada raro en todo esto —no esperaba que hubiera otros estudiantes latinos. Hoy en día, el sitio virtual de la UOP informa que hay un 23 por ciento de matriculados hispanos y un 21 por ciento de blancos no hispanos. (Me parece divertido cómo los términos junto a mi casillero étnico han cambiado a lo largo de las décadas: mexicano-americano, hispano, chicano, latino, hispano blanco, latinx).

La mezcla étnica de uoP evidencia un importante cambio social. A pesar del racismo, la cultura de la supremacía blanca y el sentimiento antiinmigrante que estamos presenciando en Estados Unidos, la mayoría de nuestras principales instituciones continúan siendo más diversas. Estamos seguros de que seremos más diversos en los próximos años, ya que los ancianos que morirán son en su mayoría blancos y la mayoría de los jóvenes son lo que ahora llamamos “personas de color”.

Más allá de estos datos demográficos de personas que ya están aquí y que nacerán aquí, estamos seguros de que seguiremos viendo una continua inmigración desde México y América Central. incluso los comentaristas conservadores —que no

A JOURNEY TO UOP

A trailblazing Mix

rev. peter Morales, sequim, Wa

son precisamente campeones del multiculturalismo y la inmigración— están reconociendo que un Estados unidos que envejece necesitará inmigrantes por razones económicas. De lo contrario, nos enfrentaremos a los problemas del envejecimiento de la población que vemos en países como Japón, Portugal, Italia y España.

Irónicamente, Portugal, Italia y España se están volviendo dependientes de una migración de adinerados europeos del norte y jubilados británicos que se están estableciendo en ciudades pequeñas —y cuyos jóvenes se han trasladado a centros urbanos como Roma, Milán, Barcelona, Madrid y Lisboa. Una similar migración inversa, aunque todavía menor, aumenta a medida que los estadounidenses y canadienses se jubilan en México y América Central.

La combinación de la necesidad estadounidense de inmigrantes, aunado a la situación desesperada de tanta gente en Guatemala, Honduras, El Salvador y el sur de México, será irresistible. Es tentador para nosotros ver a Estados unidos en algo así como la víctima pasiva de hordas humanas pregonando que se igot off the Greyhound bus in downtown Stockton 57 years ago as an entering freshman at uoP’s Raymond College, the first of the university’s new cluster colleges. i had never been to the campus. Heck, I had never been 100 miles west of my home in San Antonio, Texas. I had never seen a mountain! i was not only the only Latino in my freshman class, I was the only Hispanic in the college. it wasn’t until my sophomore year that the college enrolled its first African American student. not only was I the only Latino, but I was “imported” from texas. in other words, the college had no Hispanics from san Joaquin County or even from

California. Perhaps equally amazing, at the time I did not find any of this remarkable. I didn’t expect there would be other Latino stu-

van a “El Norte”, pero esto es un error. Estados Unidos ha contribuido a la marginación y represión de los pobres en Centroamérica con todo: desde la política comercial hasta el apoyo militar a dictaduras brutales. Compartimos un pasado común y un destino común con la gente al sur de nuestra frontera.

Los más marginados de Centroamérica y el sur de México son los pueblos indígenas, los mayas. A la opresión histórica del colonialismo que se remonta a 500 años atrás, hoy le sumamos los efectos del cambio climático que provoca sequías que arruinan cultivos y huracanes que derriban viviendas.

Estados unidos se volverá más cobrizo en los próximos 50 años. También lo es California y el Valle de san Joaquín. El desafío fundamental para todos nosotros es si podemos aprovechar las oportunidades que brinda este cambio —o si participaremos en un esfuerzo de resistencia desesperado y autodestructivo de retaguardia: construyendo muros fronterizos y arrojando a los migrantes a prisiones con fines de lucro.

Las incógnitas de política pública en este inminente cambio de- continúa a la vuelta dents. Today UOP’s website reports 23 percent Hispanic enrollment and 21 percent white non-Hispanic! (I find it amusing how the words next to my ethnicity box have changed over the decades: Mexican American, Hispanic, Chicano, Latino, white Hispanic, Latinx.)

UOP’s ethnic mix represents remarkable social change. Despite the racism, white supremacy culture and anti-immigrant feeling we are witnessing in America, most of our major institutions continue to become more diverse. We are certain to become more diverse in the coming years, as the elderly who will die are mostly white and the majority of the young are what we now call “people of color.” beyond these demographics of people already here and who will be born here, we are certain to see continued immigration from Mexico and Central America. Even conservative commentators who are not champions of multiculturalism and immigration are recognizing that an aging America will need immigrants for economic reasons. otherwise we will face the problems of an aging population that we see in countries like Japan, Portugal, italy and spain.

Ironically, Portugal, Italy and Spain are becoming dependent on a migration of affluent northern Europeans and british retirees who are settling in smaller towns whose young people have moved to urban centers like Rome, Milan, Barcelona, Madrid and Lisbon. A similar, though still small, reverse migration is occurring as Americans and Canadians retire in Mexico and Central America. the combination of America’s need for immigrants and the desperate situation of so many people in Guatemala, Honduras, El Salvador and southern Mexico will be irresistible. it is tempting for us to see the united states as somehow the passive victim of hordes of people clamoring to go to “El Norte,” but this a mistake. The United States has contributed to the marginalization of and suppression of poor people in Central America with everything from trade policy to military support for brutal dictatorships. We share a common past and a common destiny with people south of our border. continued on next page

A Trailblazing Mix

continued from last page the most marginalized of Central America and southern Mexico are the indigenous peoples, the Maya. In addition to the historic oppression of colonialism going back 500 years, today we add the effects of climate change that causes droughts that ruin crops and hurricanes that demolish homes.

America is going to become browner in the next 50 years. So is California and the San Joaquin Valley. the critical challenge for all of us is whether we can embrace the opportunities this change brings or whether we will engage in a hopeless, self-destructive rear guard effort of resistance—building border walls and throwing migrants into for-profit prisons. the public policy questions of this coming demographic shift will be many: immigration, education, health care, economics, citizenship, criminal justice, etc. The decisions we make about all of these policy issues, however, are founded upon a cultural and moral foundation. Public policy is ultimately an expression of what we believe is good, of what we think is fair, of our sense of our tribal identity and our vision of what we aspire to become. the values that can shape a thriving future are all classic virtues: empathy, respect, compassion. the cognitive foundation is pretty simple, too: a realization that we are all human and that we are in this together. It’s all simple, but not easy. it will require leadership—both from the rich and dominant north American culture, but also from the marginalized people of Meso America.

I am chair of the board of a tiny nonprofit organization that seeks to support indigenous as they struggle for human rights and to preserve cultural heritage. We named the organization “Digno” (you can check it out at digno. org). in spanish “digno” means “worthy” and “honorable.” We formed our organization because we have seen, in our case in Guatemala, how a group of indigenous people can hold a corrupt government accountable and create new opportunities for the young. this is not the place to plug our nonprofit. My point is that cooperation based on mutual respect and common goals can make a difference. It will take the work of hundreds of institutions, led by people committed to a vision of a diverse, compassionate and just society.

I believe it is a profound mistake to see the coming demographic changes primarily as public policy challenges. our challenges are not technical. Heck, we have long had the technical ability to do things like end global warming and provide universal health care. We have chosen not to. our greatest challenges are moral, emotional and even spiritual.

Fifty odd years from now a new freshman class will enter uoP. (i hope none of them stagger sleepily out of a Greyhound bus after 48 hours on the road.) it will be more diverse than the UOP and Stockton that i encountered. it will be more diverse that the san Joaquin Valley we know Peter Morales sequim, Wa today. i hope each one of these finds an environment where he or she can thrive.

Crisol Pionero

viene de la vuelta mográfico serán muchas: inmigración, educación, atención médica, economía, ciudadanía, justicia penal, etc. Sin embargo, las decisiones que tomamos sobre todas estas cuestiones de política se basan en una base cultural y moral. La política pública es, en última instancia, una expresión de lo que creemos que es bueno, de lo que creemos que es justo, de nuestro sentido de nuestra identidad tribal y nuestra visión de lo que aspiramos a convertirnos.

Los valores que pueden dar forma a un futuro próspero son todas virtudes clásicas: empatía, respeto, compasión. La base cognitiva también es bastante simple: darnos cuenta de que todos somos humanos y que estamos juntos en esto. Todo es simple, pero no fácil. Requerirá liderazgo, tanto de la rica y dominante cultura norteamericana como de la gente marginada de Mesoamérica. soy presidente de la directiva de una pequeña organización sin fines de lucro que

NOTES

1.i did not realize before i got to Pacific that they had just started another cluster, elbert covell college, in which just over half the students were from latin america or that Pacific had been a pioneer of ethnic integration since the 1800s when it welcomed asian students in the era of the asian exclusion act and that the campus was racially integrated in 1924 when it moved from san Jose to the still segregated city of stockton. 2 Pacific again provides a model of such institutional innovation as new president chris callahan has recently announced the creation of a Vice presidency for diversity, equity and inclusion that will be added to his cabinet.

NOTAS

1. antes de llegar al Pacífico, no me di cuenta de que acababan de comenzar otro grupo, elbert covell college, en el que poco más de la mitad de los estudiantes eran de américa latina o que el Pacífico había sido un pionero de la integración étnica desde el siglo xix, cuando recibió a estudiantes asiáticos. en la era de la ley de exclusión asiática y que el campus se integró racialmente en 1924 cuando se mudó de san José a la ciudad todavía segregada de stockton. 2 Pacific proporciona nuevamente un modelo de innovación institucional, ya que el nuevo presidente chris callahan anunció recientemente la creación de una Vicepresidencia de diversidad, equidad e inclusión que se agregará a su gabinete.

busca apoyar a los indígenas en su lucha por los derechos humanos y preservar su patrimonio cultural. Nombramos a la organización “Digno” (pueden consultarla en digno.org). En español, “digno” puede ser “merecedor de respeto” y “honorable”. Formamos nuestra organización porque hemos visto —en nuestro caso en Guatemala— cómo un grupo de indígenas puede hacer que un gobierno corrupto rinda cuentas… y crear nuevas oportunidades para los jóvenes. Este no es el lugar para establecer nuestra organización sin fines de lucro. Mi punto es que la cooperación basada en el respeto mutuo y objetivos comunes puede marcar la diferencia. requerirá el trabajo de cientos de instituciones, lideradas por personas comprometidas con una visión de una sociedad diversa, compasiva y justa.

Creo que es un profundo error ver los próximos cambios demográficos como nada más que desafíos de política pública. Nuestros desafíos no son técnicos. ¡Qué va! durante mucho tiempo hemos tenido la capacidad técnica para hacer cosas como poner fin al calentamiento global y brindar atención médica universal. Hemos elegido no hacerlo. nuestros mayores desafíos son morales, emocionales e incluso espirituales.

Dentro de cincuenta años y un resto, una nueva clase de primer año ingresará a la uoP. (Espero que ninguno de ellos se baje somnoliento de un Greyhound después de 48 horas en la carretera). será más diverso que el uoP y Stockton que yo encontré. Será más diverso que el Valle de san Joaquín que conocemos hoy. Espero que cada uno de ellos encuentre un entorno en el que pueda prosperar

This article is from: