RESEARCH & DEVELOPMENT
Intelligent Nanomaterials in Pharmaceutical Analysis A vision of future
Materials in nano-scale appeared as one of the phenomenal and unique materials to the modern world due to their excellent features such as high surface area, small size, high stability, high reactivity and versatile chemistry for the surface functionalisation. The physicochemical features of these materials in the range between 1 and 100 nm are completely different compared to the same materials at macroscale. These unique and great characteristics of intelligent nanomaterials make them sexcellent candidates for pharmaceutical analysis which basically determines the quality of pharmaceutical products through analytical chemistry. In this review paper, intelligent nanomaterials and their applications in pharmaceutical analysis is discussed. Innovative techniques for the application of intelligent nanomaterials in the analysis of pharmaceutical compounds in terms of various economic drawbacks, safety and health concerns of nanomaterials and life cycle assessment within pharma industry are also described. Finally, the drawbacks, challenges and new opportunities for the future design and development of intelligent nanomaterials for pharmaceutical analysis are discussed.. Rßstem Keçili, Anadolu University Yunus Emre Vocational School of Health Services, Department of Medical Services and Techniques Chaudhery Ghazanfar Hussain, Research Scholar, Computer science and Technology, Dept. of Education Lahore Chaudhery Mustansar Hussain, Department of Chemistry and Environmental Science, New Jersey Institute of Technology
32
P H A RM A F O C U S A S I A
ISSUE 39 - 2020
N
anotechnology has brought a revolution in the area of medicine and an exponential development was reported in the nanotechnology related-patents for the pharmaceutical applications in the past twenty years. The pharmaceutical companies are deeply focused on the nanotechnology to overcome the drawbacks and find out the solutions for the challenges in the production of pharmaceutical compounds and come up with safe, cheap and highly sensitive approaches and techniques for drug development. The tools in nanotechnology are adding great value to the existing commercial products thereby providing new opportunities in the various segments of R&D in pharmaceutical companies. On the other side, process development refers to both design and synthesis of pharmaceutical compounds, their intermediates, and the development of the efficient analytical techniques for diagnostic applications. A miniaturised automation platform provides the design and development of efficient high-throughput synthetic routes for the drug discovery or synthesis processes. The studies for break-
