BELGIAN RESEARCH 2020

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The Innovation Fund, the first Belgian investment fund dedicated to innovative projects in chemistry and life sciences

€3 million, with a maximum of 10% of our portfolio. We also offer start-ups professional assistance by facilitating access to our main shareholders who can be represented on their boards of directors.

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hat are the key figures and partners of The Innovation Fund? The Innovation Fund was created in 2015 with the help of shareholders sharing the same longterm vision. This fund is unique in its structure, shareholding and ambition, and far away from the mindset of financial funds: it is scheduled to operate until 2027. Since 2015 we have raised €35 million and invested an average of €5 to 7 million per year. A total of 28 investments have been made and two have already been resold. Today, we still have some 15 million euros to invest. Our aim is to achieve 50 investments, about twenty of which are to be resold, in order to build up a portfolio of some thirty holdings. To do so, we can count on our partners who include all the major European chemical companies, the main Belgian universities, and federal and regional investment companies. As an Evergreen fund we have agreed to meet again in 2027: the dividends and unpaid capital gains, by mutual agreement with our partners, are accumulated in equity in order to buy out the holdings of those who would like to opt out of the adventure at that date.

© The Innovation Fund

Could you give us some examples of companies supported by The Innovation Fund? We have made significant investments in materials, processes and life sciences. The first start-up to benefit was InOpsys, specialised in the treatment of industrial process water in the pharmaceutical industry: it developed units installed in containers in order to offer a more ecological alternative to incineration. We also support REIN4CED, which specialises in the development of carbon fibre and steel alloys, shaped by thermoplastics and robotised to produce bicycle frames. This project to reintroduce an activity that has long been relocated to China is in the scale-up phase. Another example is Tools4Patient, which develops algorithms to help predict individual placebo behaviour in clinical studies. I would also like to mention PharmaFluidics, a spin-off of Ghent University that focuses on the production of high-precision chromatographs based on microcomputer technology. To conclude, I would like to mention Spentys: this start-up is developing the scanning, modelling and 3D printing of more flexible, more airy and more suitable splints to replace the standard ones.

What support services and funding mechanisms do you offer to start-ups and innovative companies in chemistry and life sciences? We offer free assistance to start-ups in the form of equity or convertible loans representing 1 to 40% of their capital. This investment is often matched by local investment companies or university-based investment companies. It generally takes place in one or two rounds for an amount between €500,000 and

© The Innovation Fund

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Interview with Mr François CORNELIS, President of The Innovation Fund, Creator of The Innovation Circle

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What do you see as the future challenges for the financing of chemical and life sciences companies? As a seed fund The Innovation Fund is dedicated to the financing of start-ups that are still difficult to finance. Indeed they have acquired proof of concept but are still without a client or in the scale-up phase from laboratory work. It is therefore risky to finance them at this stage and even more risky to find partners willing to take this risk with us. Moreover, it is sometimes tricky to convince the manager of a start-up to raise enough funds and to favour long-term financing which gives him more respite. It is better to become rich in a company where you own 30% of the capital than to vegetate in a company where you lose 70%! There is a third challenge not to be underestimated: that of moving from inventor to entrepreneur, manager and technical director. There is a whole human resources management system to be set in motion. That said, the current opportunities are immense: we are in the midst of an intellectual renaissance and our pipeline of new projects is always full. It’s a really exciting job that ours is! And even if the choice is not always easy, we are betting more than ever on our support and consulting mission. That’s what The Innovation Circle is all about (see next page).


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True proximity between clinicians and researchers at the heart of the Charleroi CHU (University Hospital Centre

3min
page 190

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3min
pages 184-185

Alternative methods to deal with new toxins

3min
page 188

185

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pages 186-187

INFOPOLE Cluster TIC The Walloon network of digital stakeholders at the service of innovation

2min
page 181

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3min
pages 182-183

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13min
pages 174-177

CREMAN - Nuclear Magnetic Resonance Centre A well-informed partner of the industrial innovations of tomorrow

3min
pages 179-180

Aerospace and Mechanical Engineering Department – ULiège Cutting-edge research and industrial applications join forces

2min
page 178

Liège Space Centre – CSL Developing space technologies

2min
page 173

Chemical Engineering Research Unit – Liege University (ULiège) Working towards sustainable transformation processes

2min
page 167

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9min
pages 168-172

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6min
pages 164-165

Center for Education and Research on Macromolecules - CERM Polymers to serve coatings, biomaterials and energy

3min
page 166

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pages 160-163

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pages 152-155

StratiCELL Smart science dedicated to healthcare

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page 146

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pages 156-159

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pages 148-151

SOWALFIN, a key innovation stakeholder in Wallonia

2min
page 147

PDC*line Pharma Your partner in immuno-oncology

3min
page 144

Quality Assistance Analytical expertise for tomorrow’s innovative medicines

3min
page 145

Medi-Line A medical devices expert

1min
page 140

GSK Vaccines An amazing place to create the future

3min
page 139

Miracor Medical SA Cutting-edge cardiac care

3min
page 141

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pages 142-143

AbbVie Transforming patients' lives

2min
page 137

Dendrogenix A new family of molecules that fight deafness and cancer

3min
page 138

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pages 134-135

The leading expert in the tumour microenvironment

3min
page 136

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pages 132-133

Interview with Mr Julien Compère, CEO of University Hospital of Liege (CHU Liège

2min
page 127

Accessia Pharma Provide efficient tools to grow

2min
page 124

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pages 128-131

Maximising the participation of Walloon stakeholders in European research programmes

2min
page 122

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7min
pages 118-119

Sizeable investments for the life sciences

3min
page 123

SRIW, a key partner in the regional strategy for plastic recycling & circular economy

2min
page 126

Bridge2Health - B2H Providing solutions leveraging excellence

2min
page 125

Agoria Wallonia brings the technology industry into the 4.0 era

2min
page 121

Industry as the main source of technological progress

3min
page 120

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pages 112-113

Pro-Rector for Research at UCLouvain

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page 117

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pages 114-116

Haute Ecole Lucia de Brouckère Bachelor’s in medical electronics: a cutting-edge course as a response to the increasing demand for specialist technicians

2min
page 108

Haute Ecole Lucia de Brouckère Master’s in Industrial Engineering Sciences: a highly practical course that integrates research and the needs of the industrial world

3min
pages 109-111

Breast International Group (BIG): the power of international collaboration in cancer research

3min
page 105

A widely recognized expertise in interdisciplinarity

4min
page 107

Queen Fabiola Children’s University Hospital – HUDERF Ensuring optimal development of young children

3min
page 106

The central nervous system and neuroprotection as weapons in the fight against multiple sclerosis

3min
page 102

The Center for Research in Cognition & Neurosciences

3min
page 97

Recognised expert in aquaporins in Sjögren’s syndrome

3min
page 100

treatment of Alzheimer’s disease

3min
page 101

Teresinha Leal’s research on the identification of biomarkers in the sweat gland to evaluate the efficacy of treatment of Cystic Fibrosis

3min
page 104

Regenerative medicine to treat liver diseases

3min
page 103

Sabine Costagliola Lab (IRIBHM-ULB) Expert in thyroid development disorders

3min
page 99

RNA epigenetics in the battle against cancer

3min
page 98

Brussels Polytechnic School – EPB A well-renowned training course to reflect proven global standing

2min
pages 95-96

The 4MAT Department The Specialist in Inorganic Materials

2min
page 94

Vrije Universiteit Brussel - VUB Research and innovation for health

3min
pages 92-93

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pages 86-87

Université Libre de Bruxelles - ULB Interdisciplinary and interregional research for the benefit of health

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page 90

Interview with Prof. Alban de KERCHOVE d’EXAERDE, Research Director at the Laboratory of Neurophysiology of the Faculty of Medicine of the Université Libre of Brussels, President of the Belgian Society of Neuroscience, Vice-President of the Brussels Commissionon Animal Experimentation

3min
page 91

Bayer A pharmaceutical company focusing on innovation to improve patient’s quality of life and answer unmet medical needs

2min
page 85

Alcon A global leader in eye care

2min
page 84

Bolstering the appeal of ULB research centres at a global level

3min
page 89

NVS Consulting Your consultancy partner in clinical research on medicines and medical devices

2min
page 88

Nestlé Strong environmental responsibility

2min
page 83

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Towards a more open and innovative Brussels’ economy

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page 77

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pages 80-81

Nestlé Health Sciences A strong player in medical nutrition and consumer care

3min
page 82

pharma.be: Belgium, an innovative pharmavalley in Europe

3min
page 79

Accelerating innovation in medical devices and e-health for patients and healthcare providers

3min
page 76

MedTech Accelerator® Stimulating innovation in medical technologies

3min
page 78

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AZ Groeninge implements new care model from a holistic approach

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pages 64-65

Better measure the heterogeneity of inflammatory breast cancer

2min
page 61

AZ Jan Palfijn Gent Already two pregnancies after brand new Corona test at IVF

3min
page 63

Clinical research at UZ Gent: a focus on patient-oriented, personalized medicine

3min
page 57

Biotronik A leader in the field of cardiovascular devices

3min
page 56

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pages 54-55

Arseus Medical Group Innovative solutions for health professionals

2min
page 53

Fujirebio Europe A pioneer in the field of Alzheimer diagnostics

3min
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ProDigest Specialists in intestinal research

3min
page 52

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pages 48-49

PharmAbs The KU Leuven Antibody Center

3min
page 47

VAXXIUM Your partner for the development of new vaccines

2min
page 45

ECSOR Expertise at the service of clinical research

2min
page 44

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VIB: Excellence-driven basic research in life sciences with a strong societal impact

3min
page 42

Ecosynth NV Your partner for sustainable molecule and process development

2min
page 43

UZ Leuven - University Hospitals Leuven High-level research

3min
page 38

Becetel: high-performance materials research for industry and the public sector

2min
page 37

imec, a world-leading research and innovation hub in nanoelectronics and digital technologies

3min
page 39

Becetel: Belgian research centre for pipes and fittings

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VITO Reducing the risk of sustainable innovation for companies

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page 33

Flemish universities must get the necessary means to remain appealing

3min
page 31

VLAIO: a one-stop-shop for entrepreneurs in Flanders

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page 30

Improving everyone’s quality of life

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page 19

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