2021 Ingenium: Journal of Undergraduate Research

Page 111

Finite element analysis of stents under radial compression boundary conditions with different material properties Yaoyao Xua , Jonathan P. Vande Geestb

a

Department of Mechanical Engineering and Material Science, Department of Bioengineering and Department of Mechanical Engineering and Material Science b

Yaoyao Xu is a mechanical engineering undergraduate at Swanson School of Engineering. Her current interests are control, finite element analysis, and computational modeling. She plans to pursue a master’s degree in control after graduation. Yaoyao Xu

Dr. Jonathan Vande Geest is a Professor in the Department of Bioengineering, Department of Mechanical Engineering and Material Science, the Department of Ophthalmology, the McGowan Institute for Regenerative Medicine, the Louis J. Fox Center for Vision Restoration, and the Vascular Medicine Institute at the Jonathan P. Vande University of Pittsburgh. He received his Geest, Ph.D. BS in Biomedical Engineering from the University of Iowa in 2000 and his PhD in Bioengineering from the University of Pittsburgh in 2005. Dr. Vande Geest began his career at the University of Arizona in the Department of Aerospace and Mechanical Engineering and joined the University of Arizona’s Department of Biomedical Engineering in 2009. Dr. Vande Geest returned to the University of Pittsburgh in January of 2016.

Significance statement

By simulating the reactions of the cardiovascular stents in-vivo with radial compression acts as the boundary conditions, the relationships between the displacements, material stiffness, and the maximum principal stress could be found, which provides references to the stent design when large deformation causes problems to the performance of the stent.

Ingenium 2021

Abstract

The purpose of this work is to begin to establish a computational testing platform to assess the compressive behavior of magnesium alloy stents. This provides references to the stent design when large deformation causes problems to the performance of the stent. According to the results, the sensitivity of peak maximum principal stress to changes in imposed displacement increased as the stiffness of the stent increased. This sensitivity became nearly linear in both stiffness and imposed displacement when these values were near their maximum imposed values.

1. Introduction

The incidence of the cardiovascular and cerebrovascular disease has become higher and higher in recent years and has become the main threat to human life and health [1]. About 80% of patients with the cerebrovascular disease have the ischemic stroke, the main cause of which is the narrowing of blood vessels [2]. A cardiac stent is used to treat narrowed or blocked coronary arteries. Stent restenosis is a major problem resulting in device and treatment failure and often requires subsequent reintervention. The method of finite elements analyzes the structural characteristics that affect the support strength and safety of vascular stents. Through mechanical simulation and numerical study of the releasing and operating process of vascular stents in the stenosis model, the relevant factors that influence the effect of stent expansion can be identified, which can be provided to the physician when using stent implantation as a valuable reference. Previous research has found that restenosis within balloon-expandable endovascular stents may occur as a result of radial compression [3], and radial compression acts as one of the common boundary conditions for cardiovascular stents in-vivo [4]. Based on Hooke’s law, we assume that the maximum principal stress of the stent is inversely proportional to material stiffness with the same displacement, and as the displacement increases, the stress will also increase. The purpose of this work is to begin to establish a computational testing platform to assess the compressive behavior of magnesium alloy stents. This provides references to the stent design when large deformation causes problems to the performance of the stent.

Category: Computational Research Keywords: Simulation, Stent, Abaqus, Radial compression, Stiffness

111


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Index

2min
pages 114-115

u Neural Network-based approximation of model predictive control applied to a flexible shaft servomechanism

13min
pages 107-110

Department of Bioengineering, McGowan Institute for Regenerative Medicine, Renerva, LLC

15min
pages 102-106

u Finite element analysis of stents under radial compression boundary conditions with different material properties

8min
pages 111-113

Analysis of stride segmentation methods to identify heel strike

14min
pages 98-101

Joseph Sukinik, Rosh Bharthi, Sarah Hemler, Kurt Beschorner

13min
pages 94-97

Human Movement and Balance Laboratory, Department of Bioengineering; Falls, Balance, and Injury Research Centre, Neuroscience Research Australia

10min
pages 90-93

u Topological descriptor selection for a quantitative structure-activity relationship (QSAR) model to assess PAH mutagenicity

12min
pages 81-84

Department of Bioengineering, Department of Electrical Engineering, Department of Mechanical Engineering, Innovation, Product Design, and Entrepreneurship Program

12min
pages 85-89

Department of Chemical Engineering, Heart, Lung, Blood, and Vascular Medicine Institute Division of Pulmonary, Allergy and Critical Care Medicine

14min
pages 76-80

u Demonstrating the antibiofouling property of the Clanger cicada wing with ANSYS Fluent simulations

13min
pages 72-75

u Levator Ani muscle dimension changes with gestational and maternal age

11min
pages 64-67

u Bioinformatic analysis of fibroblast-mediated therapy resistance in HER2+ breast cancer

11min
pages 60-63

Department of Bioengineering, Department of Psychiatry, Department of Neurology, Physician Scientist Training Program, University of Pittsburgh School of Medicine

15min
pages 55-59

u Fluid flow simulation of microphysiological knee joint-on-a-chip

14min
pages 49-54

Department of Bioengineering, Division of Vascular Surgery, University of Pittsburgh Medical Center, Department of Surgery, Department of Cardiothoracic Surgery, and Department of Chemical and Petroleum Engineering, McGowan Institute for Regenerative Medicine, and Center for Vascular Remodeling and Regeneration

16min
pages 44-48

Testing the compressive stiffness of endovascular devices

11min
pages 40-43

Department of Bioengineering, Carnegie Mellon University, McGowan Institute of Regenerative Medicine

15min
pages 35-39

Physical Metallurgy & Materials Design Laboratory, Department of Mechanical Engineering & Material Science

13min
pages 25-29

Hardware acceleration of k-means clustering for satellite image compression

15min
pages 20-24

Visualization and Image Analysis (VIA) Laboratory, Department of Bioengineering

16min
pages 30-34

Spike decontamination in local field potential signals from the primate superior colliculus

10min
pages 16-19

u Simulating the effect of different structures and materials on OLED extraction efficiency

8min
pages 13-15

u Representations of population activity during sensorimotor transformation for visually guided eye movements

14min
pages 7-12

Message from the Coeditors in Chief

2min
page 5

A Message from the Associate Dean for Research

3min
page 4
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